TY  - CHAP
A1  - Lei, Yu
A1  - Mulchandani, Priti
A1  - Chen, Wilfred
A1  - Mulchandani, Ashok
T1  - Biosensor for direct determination of fenitrothion and EPN using recombinant Pseudomonas putida JS444 with surface expressed organophosphorus hydrolase. 1. modified clark oxygen electrode
N2  - This paper reports a first microbial biosensor for rapid and cost-effective determination of organophosphorus pesticides fenitrothion and EPN. The biosensor consisted of recombinant PNP-degrading/oxidizing bacteria Pseudomonas putida JS444 anchoring and displaying organophosphorus hydrolase (OPH) on its cell surface as biological sensing element and a dissolved oxygen electrode as the transducer. Surfaceexpressed OPH catalyzed the hydrolysis of fenitrothion and EPN to release 3-methyl-4-nitrophenol and p-nitrophenol, respectively, which were oxidized by the enzymatic machinery of Pseudomonas putida JS444 to carbon dioxide while consuming oxygen, which was measured and correlated to the concentration of organophosphates. Under the optimum operating conditions, the biosensor was able to measure as low as 277 ppb of fenitrothion and 1.6 ppm of EPN without interference from phenolic compounds and other commonly used pesticides such as carbamate pesticides, triazine herbicides and organophosphate pesticides without nitrophenyl substituent. The applicability of the biosensor to lake water was also demonstrated.
KW  - Biosensor
KW  - Organophosphorus
KW  - fenitrothion
KW  - EPN
KW  - biosensor
KW  - Pseudomonas putida
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1573
ER  - 
TY  - JOUR
A1  - Lehnertz, Klaus
A1  - Mormann, Florian
A1  - Osterhage, Hannes
A1  - Andy, Müller
A1  - Prusseit, Jens
A1  - Chernihovskyi, Anton
A1  - Staniek, Matthäus
A1  - Krug, Dieter
A1  - Bialonski, Stephan
A1  - Elger, Christian E.
T1  - State-of-the-art of seizure prediction
JF  - Journal of Clinical Neurophysiology
Y1  - 2007
U6  - http://dx.doi.org/10.1097/WNP.0b013e3180336f16
SN  - 1537-1603
VL  - 24
IS  - 2
SP  - 147
EP  - 153
ER  - 
TY  - CHAP
A1  - Lehnertz, Klaus
A1  - Bialonski, Stephan
A1  - Horstmann, Marie-Therese
A1  - Krug, Dieter
A1  - Rothkegel, Alexander
A1  - Staniek, Matthäus
A1  - Wagner, Tobias
T1  - Epilepsy
T2  - Reviews of Nonlinear Dynamics and Complexity, Volume 2
Y1  - 2010
SN  - 9783527628001
U6  - http://dx.doi.org/10.1002/9783527628001.ch5
SP  - 159
EP  - 200
PB  - Wiley-VCH
ER  - 
TY  - JOUR
A1  - Lehnertz, Klaus
A1  - Bialonski, Stephan
A1  - Horstmann, Marie-Therese
A1  - Krug, Dieter
A1  - Rothkegel, Alexander
A1  - Staniek, Matthäus
A1  - Wagner, Tobias
T1  - Synchronization phenomena in human epileptic brain networks
JF  - Journal of neuroscience methods
Y1  - 2009
U6  - http://dx.doi.org/10.1016/j.jneumeth.2009.05.015
SN  - 0165-0270
VL  - 183
IS  - 1
SP  - 42
EP  - 48
ER  - 
TY  - JOUR
A1  - Lehnertz, Klaus
A1  - Ansmann, Gerrit
A1  - Bialonski, Stephan
A1  - Dickten, Henning
A1  - Geier, Christian
A1  - Porz, Stephan
T1  - Evolving networks in the human epileptic brain
JF  - Physica D: Nonlinear Phenomena
N2  - Network theory provides novel concepts that promise an improved characterization of interacting dynamical systems. Within this framework, evolving networks can be considered as being composed of nodes, representing systems, and of time-varying edges, representing interactions between these systems. This approach is highly attractive to further our understanding of the physiological and pathophysiological dynamics in human brain networks. Indeed, there is growing evidence that the epileptic process can be regarded as a large-scale network phenomenon. We here review methodologies for inferring networks from empirical time series and for a characterization of these evolving networks. We summarize recent findings derived from studies that investigate human epileptic brain networks evolving on timescales ranging from few seconds to weeks. We point to possible pitfalls and open issues, and discuss future perspectives.
Y1  - 2014
U6  - http://dx.doi.org/10.1016/j.physd.2013.06.009
SN  - 0167-2789
VL  - 267
SP  - 7
EP  - 15
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Laura, C.O.
A1  - Drechsler, Klaus
A1  - Erdt, M.
A1  - Wesarg, S.
A1  - Bale, R.
T1  - Intervention assessment tool for primary tumors in the liver
JF  - Current Directions in Biomedical Engineering
N2  - After a liver tumor intervention the medical doctor has to compare both pre and postoperative CT acquisitions to ensure that all carcinogenic cells are destroyed. A correct assessment of the intervention is of vital importance, since it will reduce the probability of tumor recurrence. Some methods have been proposed to support the medical doctors during the assessment process, however, all of them focus on secondary tumors. In this paper a tool is presented that enables the outcome validation for both primary and secondary tumors. Therefore, a multiphase registration (preoperative arterial and portal phases) followed by a registration between the pre and postoperative CT images is carried out. The first registration is in charge of the primary tumors that are only visible in the arterial phase. The secondary tumors will be incorporated in the second registration step. Finally, the part of the tumor that was not covered by the necrosis is quantified and visualized. The method has been tested in 9 patients, with an average registration error of 1.41 mm.
Y1  - 2018
U6  - http://dx.doi.org/10.1515/cdbme-2018-0081
SN  - 2364-5504
VL  - 4
IS  - 1
SP  - 337
EP  - 340
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Lapitan, Denis G.
A1  - Rogatkin, Dmitrii A.
A1  - Persheyev, Sydulla K.
A1  - Kotliar, Konstantin
T1  - False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter
JF  - Biomedizinische Technik
N2  - Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise.
Y1  - 2018
U6  - http://dx.doi.org/10.1515/bmt-2017-0060
SN  - 0013-5585
VL  - 63
IS  - 4
SP  - 439
EP  - 444
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Lanzl, Ines M.
A1  - Seidova, Seid-Fatima
A1  - Maier, Mathias
A1  - Schmidt-Trucksäss, Arno
A1  - Halle, Martin
A1  - Kotliar, Konstantin
T1  - Dynamic retinal vessel response to flicker in age-related macular degeneration patients before and after vascular endothelial growth factor inhibitor injection
JF  - Acta Ophthalmologica
Y1  - 2011
SN  - 1755-3768
VL  - 89
IS  - 5
SP  - 472
EP  - 479
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Langen, Karl J.
A1  - Ziemons, Karl
A1  - Kiwit, Jürgen C. W.
A1  - Herzog, Hans
A1  - Kuwert, Torsten
A1  - Bock, Wolfgang
A1  - Stöcklin, Gerhard
A1  - Feinendegen, Ludwig E.
A1  - Müller-Gärtner, Hans-W.
T1  - 3-[123I]iodo-α-methyltyrosine and [methyl-11C]-L-methionine uptake in cerebral gliomas: a compara-tive study using SPECT and PET
JF  - Journal of Nuclear Medicine
Y1  - 1997
SN  - 0161-5505
VL  - 38
IS  - 4
SP  - 517
EP  - 522
ER  - 
TY  - JOUR
A1  - Laack, Walter van
A1  - Refisch, A.
T1  - Neuralgic amyotrophy of the lumbar area. Case Report / Refisch, A. ; Laack, W. van
JF  - Archives of Orthopaedic and Trauma Surgery. 108 (1989), H. 5
Y1  - 1989
SN  - 0936-8051
SP  - 329
EP  - 332
ER  -