TY  - JOUR
A1  - Doorschodt, B. M.
A1  - Schreinemachers, M. C. J. M.
A1  - Behbahani, Mehdi
A1  - Florquin, S.
A1  - Weis, J.
A1  - Staat, Manfred
A1  - Tolba, R. H.
T1  - Hypothermic machine perfusion of kidney grafts: which pressure is preferred
JF  - Annals of Biomedical Engineering. 39 (2011), H. 3
Y1  - 2011
SN  - 1573-9686
SP  - 1051
EP  - 1059
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Grotendorst, Johannes
T1  - IAS Winter School: Hierarchical Methods for Dynamics in Complex Molecular Systems
JF  - Innovatives Supercomputing in Deutschland : inSiDE
Y1  - 2012
VL  - 10
SP  - 104
EP  - 1
PB  - HLRS
CY  - Stuttgart
ER  - 
TY  - CHAP
A1  - Dachwald, Bernd
A1  - Ulamec, Stephan
A1  - Kowalski, Julia
A1  - Boxberg, Marc S.
A1  - Baader, Fabian
A1  - Biele, Jens
A1  - Kömle, Norbert
ED  - Badescu, Viorel
ED  - Zacny, Kris
ED  - Bar-Cohen, Yoseph
T1  - Ice melting probes
T2  - Handbook of Space Resources
N2  - The exploration of icy environments in the solar system, such as the poles of Mars and the icy moons (a.k.a. ocean worlds), is a key aspect for understanding their astrobiological potential as well as for extraterrestrial resource inspection. On these worlds, ice melting probes are considered to be well suited for the robotic clean execution of such missions. In this chapter, we describe ice melting probes and their applications, the physics of ice melting and how the melting behavior can be modeled and simulated numerically, the challenges for ice melting, and the required key technologies to deal with those challenges. We also give an overview of existing ice melting probes and report some results and lessons learned from laboratory and field tests.
KW  - Ice melting probe
KW  - Ice penetration
KW  - Icy moons
KW  - Ocean worlds
KW  - Mars
Y1  - 2023
SN  - 978-3-030-97912-6 (Print)
SN  - 978-3-030-97913-3 (Online)
U6  - https://doi.org/10.1007/978-3-030-97913-3_29
SP  - 955
EP  - 996
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Dachwald, Bernd
A1  - Mikucki, Jill
A1  - Tulaczyk, Slawek
A1  - Digel, Ilya
A1  - Espe, Clemens
A1  - Feldmann, Marco
A1  - Francke, Gero
A1  - Kowalski, Julia
A1  - Xu, Changsheng
T1  - IceMole : A maneuverable probe for clean in situ analysis and sampling of subsurface ice and subglacial aquatic ecosystems
JF  - Annals of Glaciology
N2  - There is significant interest in sampling subglacial environments for geobiological studies, but they are difficult to access. Existing ice-drilling technologies make it cumbersome to maintain microbiologically clean access for sample acquisition and environmental stewardship of potentially fragile subglacial aquatic ecosystems. The IceMole is a maneuverable subsurface ice probe for clean in situ analysis and sampling of glacial ice and subglacial materials. The design is based on the novel concept of combining melting and mechanical propulsion. It can change melting direction by differential heating of the melting head and optional side-wall heaters. The first two prototypes were successfully tested between 2010 and 2012 on glaciers in Switzerland and Iceland. They demonstrated downward, horizontal and upward melting, as well as curve driving and dirt layer penetration. A more advanced probe is currently under development as part of the Enceladus Explorer (EnEx) project. It offers systems for obstacle avoidance, target detection, and navigation in ice. For the EnEx-IceMole, we will pay particular attention to clean protocols for the sampling of subglacial materials for biogeochemical analysis. We plan to use this probe for clean access into a unique subglacial aquatic environment at Blood Falls, Antarctica, with return of a subglacial brine sample.
KW  - Antarctic Glaciology
KW  - Extraterrestrial Glaciology
KW  - Glaciological instruments and methods
KW  - Subclacial exploration
KW  - Subglacial lakes
Y1  - 2014
U6  - https://doi.org/10.3189/2014AoG65A004
SN  - 1727-5644
VL  - 55
IS  - 65
SP  - 14
EP  - 22
PB  - Cambridge University Press
CY  - Cambridge
ER  - 
TY  - CHAP
A1  - Dachwald, Bernd
A1  - Xu, Changsheng
A1  - Feldmann, Marco
A1  - Plescher, Engelbert
T1  - IceMole : Development of a novel subsurface ice probe and testing of the first prototype on the Morteratsch Glacier
T2  - EGU General Assembly 2011 Vienna | Austria | 03 – 08 April 2011
N2  - We present the novel concept of a combined drilling and melting probe for subsurface ice research. This probe, named “IceMole”, is currently developed, built, and tested at the FH Aachen University of Applied Sciences’ Astronautical Laboratory. Here, we describe its first prototype design and report the results of its field tests on the Swiss Morteratsch glacier. Although the IceMole design is currently adapted to terrestrial glaciers and ice shields, it may later be modified for the subsurface in-situ investigation of extraterrestrial ice, e.g., on Mars, Europa, and Enceladus. If life exists on those bodies, it may be present in the ice (as life can also be found in the deep ice of Earth).
Y1  - 2011
ER  - 
TY  - JOUR
A1  - Hillen, Walter
A1  - Lehmann, T.
A1  - Horn, H.
A1  - Schmitt, W.
T1  - IDEFIX - Identification of Dental Fixtures. Lehmann, T.; Hillen, W.; Horn, H.; Schmitt, W.
JF  - 5th European Congress on Dental and Maxillo-Facial Radiology : 30th Annual meeting of Working Group for Dental Radiology in the German Scientific Society for Dentistry, November 8-11, 1995, Cologne : abstracts
Y1  - 1995
N1  - European Congress on Dental and Maxillo-Facial Radiology <5, 1995, Köln>
ER  - 
TY  - JOUR
A1  - Werfel, Stanislas
A1  - Günthner, Roman
A1  - Hapfelmeier, Alexander
A1  - Hanssen, Henner
A1  - Kotliar, Konstantin
A1  - Heemann, Uwe
A1  - Schmaderer, Christoph
ED  - Guzik, Tomasz J.
T1  - Identification of cardiovascular high-risk groups from dynamic retinal vessel signals using untargeted machine learning
JF  - Cardiovascular Research
N2  - Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine learning on DVA in order to improve CV mortality prediction and identify corresponding response alterations.
KW  - Machine learning
KW  - Retinal vessels
KW  - Microcirculation
KW  - Haemodialysis
KW  - Myocardial infarction and cardiac death
Y1  - 2022
U6  - https://doi.org/10.1093/cvr/cvab040
SN  - 0008-6363
VL  - 118
IS  - 2
SP  - 612
EP  - 621
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Hillen, Walter
A1  - Lehmann, T.
A1  - Horn, H.
A1  - Schmitt, W.
T1  - Identification of Dental Fixtures in Intraoral X-rays. Lehmann, T.; Hillen, W.; Horn, H.; Schmitt, W.
JF  - Medical  imaging  1996 : image processing ; 12 - 15 February 1996, Newport Beach, California / Murray H. Loew ... chairs/ed.
Y1  - 1996
SN  - 0-8194-2085-9
N1  - Proceedings of SPIE; 2710
SP  - 584
EP  - 584
PB  - SPIE - The International Society for Optical Engineering
CY  - Bellingham, Wash.
ER  - 
TY  - JOUR
A1  - Lempiäinen, Harri
A1  - Couttet, Philippe
A1  - Bolognani, Federico
A1  - Müller, Arne
A1  - Dubost, Valérie
A1  - Luisier, Raphaëlle
A1  - Rio-Espinola, Alberto del
A1  - Vitry, Veronique
A1  - Unterberger, Elif B.
A1  - Thomson, John P.
A1  - Treindl, Fridolin
A1  - Metzger, Ute
A1  - Wrzodek, Clemens
A1  - Hahne, Florian
A1  - Zollinger, Tulipan
A1  - Brasa, Sarah
A1  - Kalteis, Magdalena
A1  - Marcellin, Magali
A1  - Giudicelli, Fanny
A1  - Braeuning, Albert
A1  - Morawiec, Laurent
A1  - Zamurovic, Natasa
A1  - Längle, Ulrich
A1  - Scheer, Nico
A1  - Schübeler, Dirk
A1  - Goodman, Jay
A1  - Chibout, Salah-Dine
A1  - Marlowe, Jennifer
A1  - Theil, Dietlinde
A1  - Heard, David J.
A1  - Grenet, Olivier
A1  - Zell, Andreas
A1  - Templin, Markus F.
A1  - Meehan, Richard R.
A1  - Wolf, Roland C.
A1  - Elcombe, Clifford R.
A1  - Schwarz, Michael
A1  - Moulin, Pierre
A1  - Terranova, Rémi
A1  - Moggs, Jonathan G.
T1  - Identification of Dlk1-Dio3 imprinted gene cluster non-coding RNAs as novel candidate biomarkers for liver tumor promotion
JF  - Toxicological Sciences
N2  - The molecular events during nongenotoxic carcinogenesis and their temporal order are poorly understood but thought to include long-lasting perturbations of gene expression. Here, we have investigated the temporal sequence of molecular and pathological perturbations at early stages of phenobarbital (PB) mediated liver tumor promotion in vivo. Molecular profiling (mRNA, microRNA [miRNA], DNA methylation, and proteins) of mouse liver during 13 weeks of PB treatment revealed progressive increases in hepatic expression of long noncoding RNAs and miRNAs originating from the Dlk1-Dio3 imprinted gene cluster, a locus that has recently been associated with stem cell pluripotency in mice and various neoplasms in humans. PB induction of the Dlk1-Dio3 cluster noncoding RNA (ncRNA) Meg3 was localized to glutamine synthetase-positive hypertrophic perivenous hepatocytes, sug- gesting a role for β-catenin signaling in the dysregulation of Dlk1-Dio3 ncRNAs. The carcinogenic relevance of Dlk1-Dio3 locus ncRNA induction was further supported by in vivo genetic dependence on constitutive androstane receptor and β-catenin pathways. Our data identify Dlk1-Dio3 ncRNAs as novel candidate early biomarkers for mouse liver tumor promotion and provide new opportunities for assessing the carcinogenic potential of novel compounds.
Y1  - 2012
U6  - https://doi.org/10.1093/toxsci/kfs303
SN  - 1094-2025
VL  - 131
IS  - 2
SP  - 375
EP  - 386
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - CHAP
A1  - Kalbe, Jochen
A1  - Kuropka, Rolf
A1  - Meyer-Stork, L. Sebastian
A1  - Lauter, S. L.
A1  - Höcker, Hartwig
A1  - Berndt, Heinz
ED  - Körner, Andrea
T1  - Identification of fine animal hair via DNA analysis
T2  - Proceedings of the 1st International Symposium on Specialty Animal Fibers : Aachen, October 26 - 27, 1987 ; [scientific, technological and economical aspects] . - (Schriftenreihe des Deutschen Wollforschungsinstitutes an der Technischen Hochschule Aachen e.V. ; 103)
Y1  - 1988
SN  - 0930-3723
SP  - 221
EP  - 227
PB  - Dt. Wollforschungsinst.
CY  - Aachen
ER  -