TY - JOUR A1 - Vorst, Phillip A1 - Ferrein, Alexander A1 - Lakemeyer, Gerhard T1 - AllemaniACs3D team description Y1 - 2006 SP - 1 EP - 6 ER - TY - CHAP A1 - Ferrein, Alexander A1 - Lakemeyer, Gerhard A1 - Schiffer, Stefan T1 - AllemaniACs@ home 2006 team description Y1 - 2006 SP - 1 EP - 6 ER - TY - JOUR A1 - Gaigall, Daniel ED - AitSahlia, Farid T1 - Allocating and forecasting changes in risk JF - Journal of risk N2 - We consider time-dependent portfolios and discuss the allocation of changes in the risk of a portfolio to changes in the portfolio’s components. For this purpose we adopt established allocation principles. We also use our approach to obtain forecasts for changes in the risk of the portfolio’s components. To put the approach into practice we present an implementation based on the output of a simulation. Allocation is illustrated with an example portfolio in the context of Solvency II. The quality of the forecasts is investigated with an empirical study. KW - portfolio risk KW - allocation KW - forecast KW - covariance principle KW - conditional expectation principle Y1 - 2023 U6 - http://dx.doi.org/10.21314/JOR.2022.048 SN - 1755-2842 SN - 1465-1211 VL - 25 IS - 3 SP - 1 EP - 24 PB - Infopro Digital Risk CY - London ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Mohr, P. A1 - Staudt, G. T1 - Alpha-cluster states of 212po in a realistic potential model JF - Physical review / C. 50 (1994), H. 5 Y1 - 1994 SN - 0556-2813 SP - 2631 EP - 2634 ER - TY - CHAP A1 - Ziolko, C. A1 - Schmitz, M. A1 - Sattler, Johannes, Christoph A1 - Khedim, Ahmed A1 - Hoffschmidt, Bernhard T1 - AlSol - the open volumetric receiver technology moves to Africa T2 - SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France Y1 - 2010 SP - 93 EP - 94 PB - Soc. OSC CY - Saint Maur ER - TY - JOUR A1 - Prielmeier, Franz A1 - Wick, Markus A1 - Nagatomo, Yasushi A1 - Frahm, Jens T1 - Alteration of Intracellular Metabolite Diffusion in Rat Brain In Vivo During Ischemia and Reperfusion / Markus Wick, Yasushi Nagatomo, Franz Prielmeier, Jens Frahm JF - Stroke. 26 (1995), H. 10 Y1 - 1995 SN - 0039-2499 SP - 1930 EP - 1934 ER - TY - JOUR A1 - Bassam, Rasha A1 - Artmann, Gerhard A1 - Hescheler, Jürgen A1 - Graef, T. A1 - Temiz Artmann, Aysegül A1 - Porst, Dariusz A1 - Linder, Peter A1 - Kayser, Peter A1 - Arinkin, Vladimir A1 - Gossmann, Matthias A1 - Digel, Ilya T1 - Alterations in human hemoglobin structure related to red blood cell storage N2 - The importance of the availability of stored blood or blood cells, respectively, for urgent transfusion cannot be overestimated. Nowadays, blood storage becomes even more important since blood products are used for epidemiological studies, bio-technical research or banked for transfusion purposes. Thus blood samples must not only be processed, stored, and shipped to preserve their efficacy and safety, but also all parameters of storage must be recorded and reported for Quality Assurance. Therefore, blood banks and clinical research facilities are seeking more accurate, automated means for blood storage and blood processing. KW - Hämoglobin KW - Hämoglobinstruktur KW - Blutzellenlagerung KW - Hemoglobin structure KW - Red blood cell storage Y1 - 2011 ER - TY - JOUR A1 - Stäudle, Benjamin A1 - Seynnes, Olivier A1 - Laps, Guido A1 - Brüggemann, Gert-Peter A1 - Albracht, Kirsten T1 - Altered gastrocnemius contractile behavior in former achilles tendon rupture patients during walking JF - Frontiers in Physiology N2 - Achilles tendon rupture (ATR) remains associated with functional limitations years after injury. Architectural remodeling of the gastrocnemius medialis (GM) muscle is typically observed in the affected leg and may compensate force deficits caused by a longer tendon. Yet patients seem to retain functional limitations during—low-force—walking gait. To explore the potential limits imposed by the remodeled GM muscle-tendon unit (MTU) on walking gait, we examined the contractile behavior of muscle fascicles during the stance phase. In a cross-sectional design, we studied nine former patients (males; age: 45 ± 9 years; height: 180 ± 7 cm; weight: 83 ± 6 kg) with a history of complete unilateral ATR, approximately 4 years post-surgery. Using ultrasonography, GM tendon morphology, muscle architecture at rest, and fascicular behavior were assessed during walking at 1.5 m⋅s–1 on a treadmill. Walking patterns were recorded with a motion capture system. The unaffected leg served as control. Lower limbs kinematics were largely similar between legs during walking. Typical features of ATR-related MTU remodeling were observed during the stance sub-phases corresponding to series elastic element (SEE) lengthening (energy storage) and SEE shortening (energy release), with shorter GM fascicles (36 and 36%, respectively) and greater pennation angles (8° and 12°, respectively). However, relative to the optimal fascicle length for force production, fascicles operated at comparable length in both legs. Similarly, when expressed relative to optimal fascicle length, fascicle contraction velocity was not different between sides, except at the time-point of peak series elastic element (SEE) length, where it was 39 ± 49% lower in the affected leg. Concomitantly, fascicles rotation during contraction was greater in the affected leg during the whole stance-phase, and architectural gear ratios (AGR) was larger during SEE lengthening. Under the present testing conditions, former ATR patients had recovered a relatively symmetrical walking gait pattern. Differences in seen AGR seem to accommodate the profound changes in MTU architecture, limiting the required fascicle shortening velocity. Overall, the contractile behavior of the GM fascicles does not restrict length- or velocity-dependent force potentials during this locomotor task. KW - tendon rupture KW - muscle fascicle behavior KW - walking gait KW - force generation KW - ultrasound imaging Y1 - 2022 U6 - http://dx.doi.org/10.3389/fphys.2022.792576 SN - 1664-042X VL - 13 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Hauser, Christine A1 - Ortner, Marion A1 - Muggenthaler, Claudia A1 - Diehl-Schmid, Janine A1 - Angermann, Susanne A1 - Hapfelmeier, Alexander A1 - Schmaderer, Christoph A1 - Grimmer, Timo T1 - Altered neurovascular coupling as measured by optical imaging: a biomarker for Alzheimer’s disease JF - Scientific Reports Y1 - 2017 U6 - http://dx.doi.org/10.1038/s41598-017-13349-5 SN - 2045-2322 N1 - Article 12906 VL - 7 IS - 1 SP - 1 EP - 11 PB - Springer Nature CY - Cham ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Ortner, Marion A1 - Conradi, Anna A1 - Hacker, Patricia A1 - Hauser, Christine A1 - Günthner, Roman A1 - Moser, Michaela A1 - Muggenthaler, Claudia A1 - Diehl-Schmid, Janine A1 - Priller, Josef A1 - Schmaderer, Christoph A1 - Grimmer, Timo T1 - Altered retinal cerebral vessel oscillation frequencies in Alzheimer's disease compatible with impaired amyloid clearance JF - Neurobiology of Aging N2 - Retinal vessels are similar to cerebral vessels in their structure and function. Moderately low oscillation frequencies of around 0.1 Hz have been reported as the driving force for paravascular drainage in gray matter in mice and are known as the frequencies of lymphatic vessels in humans. We aimed to elucidate whether retinal vessel oscillations are altered in Alzheimer's disease (AD) at the stage of dementia or mild cognitive impairment (MCI). Seventeen patients with mild-to-moderate dementia due to AD (ADD); 23 patients with MCI due to AD, and 18 cognitively healthy controls (HC) were examined using Dynamic Retinal Vessel Analyzer. Oscillatory temporal changes of retinal vessel diameters were evaluated using mathematical signal analysis. Especially at moderately low frequencies around 0.1 Hz, arterial oscillations in ADD and MCI significantly prevailed over HC oscillations and correlated with disease severity. The pronounced retinal arterial vasomotion at moderately low frequencies in the ADD and MCI groups would be compatible with the view of a compensatory upregulation of paravascular drainage in AD and strengthen the amyloid clearance hypothesis. KW - Alzheimer's disease KW - Retinal vessel analysis KW - Vasomotions KW - Pulsations KW - Mild cognitive impairment Y1 - 2022 U6 - http://dx.doi.org/10.1016/j.neurobiolaging.2022.08.012 SN - 0197-4580 VL - 120 SP - 117 EP - 127 PB - Elsevier CY - Amsterdam ER -