TY - JOUR A1 - Hagemann, Hans-Jürgen A1 - Hennings, D. T1 - Reversible Weight change of acceptor-doped BaTiO3. Hagemann, H. J.; Hennings, D. JF - Journal of the American Ceramic Society. 64 (1981) Y1 - 1981 SN - 0002-7820 SP - 590 EP - 594 ER - TY - JOUR A1 - Kämper, Klaus-Peter A1 - Pappas, D. P. A1 - Hopster, H. T1 - Reversible transition between perpendicular and in-plane magnetization in ultrathin films. Pappas, D. P.; Kämper, K.-P.; Hopster, H. JF - Physical Review Letters. 64 (1990), H. 26 Y1 - 1990 SN - 1079-7114 SP - 3179 EP - 3182 ER - TY - JOUR A1 - Seibler, Jost A1 - Kleinridders, Andre A1 - Küter-Luks, Birgit A1 - Niehaves, Sandra A1 - Brüning, Jens C. A1 - Schwenk, Frieder T1 - Reversible gene knockdown in mice using a tight, inducible shRNA expression system JF - Nucleic Acids Research Y1 - 2007 U6 - http://dx.doi.org/10.1093/nar/gkm122 SN - 1362-4962 VL - 35 IS - 7 SP - e54 ER - TY - JOUR A1 - Rhoden, Imke A1 - Ball, Christopher Stephen A1 - Grajewski, Matthias A1 - Kuckshinrich, Wilhelm T1 - Reverse engineering of stakeholder preferences – A multi-criteria assessment of the German passenger car sector JF - Renewable and Sustainable Energy Reviews N2 - Germany is a frontrunner in setting frameworks for the transition to a low-carbon system. The mobility sector plays a significant role in this shift, affecting different people and groups on multiple levels. Without acceptance from these stakeholders, emission targets are out of reach. This research analyzes how the heterogeneous preferences of various stakeholders align with the transformation of the mobility sector, looking at the extent to which the German transformation paths are supported and where stakeholders are located. Under the research objective of comparing stakeholders' preferences to identify which car segments require additional support for a successful climate transition, a status quo of stakeholders and car performance criteria is the foundation for the analysis. Stakeholders' hidden preferences hinder the derivation of criteria weightings from stakeholders; therefore, a ranking from observed preferences is used. This study's inverse multi-criteria decision analysis means that weightings can be predicted and used together with a recalibrated performance matrix to explore future preferences toward car segments. Results show that stakeholders prefer medium-sized cars, with the trend pointing towards the increased potential for alternative propulsion technologies and electrified vehicles. These insights can guide the improved targeting of policy supporting the energy and mobility transformation. Additionally, the method proposed in this work can fully handle subjective approaches while incorporating a priori information. A software implementation of the proposed method completes this work and is made publicly available. KW - Regionalization KW - Multi-criteria decision analysis KW - Preference assessment KW - E-Mobility KW - Mobility transition Y1 - 2023 U6 - http://dx.doi.org/10.1016/j.rser.2023.113352 SN - 1364-0321 VL - 181 IS - July 2023 SP - Article number: 113352 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Neumaier, Felix A1 - Kotliar, Konstantin A1 - Haeren, Roel Hubert Louis A1 - Temel, Yasin A1 - Lüke, Jan Niklas A1 - Seyam, Osama A1 - Lindauer, Ute A1 - Clusmann, Hans A1 - Hescheler, Jürgen A1 - Schubert, Gerrit Alexander A1 - Schneider, Toni A1 - Albanna, Walid T1 - Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA) JF - Frontiers in Neurology Y1 - 2021 U6 - http://dx.doi.org/10.3389/fneur.2021.659890 VL - 12 SP - 1 EP - 11 PB - Frontiers ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Vilser, Walthatd A1 - Nagel, Edgar A1 - Lanzl, Ines M. T1 - Retinal vessel reaction in response to chromatic flickering light / Kotliar, Konstantin E. ; Vilser, Walthard ; Nagel, Edgar ; Lanzl, Ines M. JF - Graefe's Archive for Clinical and Experimental Ophthalmology. 242 (2004), H. 5 Y1 - 2004 SN - 1435-702X SP - 377 EP - 392 PB - - ER - TY - JOUR A1 - Smith, Wayne A1 - Kotliar, Konstantin A1 - Lammertyn, Leandi A1 - Ramoshaba, Nthai E. A1 - Vilser, Walthard A1 - Huisman, Hugo W. A1 - Schutte, Aletta E. T1 - Retinal vessel caliber and caliber responses in true normotensive black and white adults: The African-PREDICT study JF - Microvascular Research N2 - Purpose Globally, a detrimental shift in cardiovascular disease risk factors and a higher mortality level are reported in some black populations. The retinal microvasculature provides early insight into the pathogenesis of systemic vascular diseases, but it is unclear whether retinal vessel calibers and acute retinal vessel functional responses differ between young healthy black and white adults. Methods We included 112 black and 143 white healthy normotensive adults (20–30 years). Retinal vessel calibers (central retinal artery and vein equivalent (CRAE and CRVE)) were calculated from retinal images and vessel caliber responses to flicker light induced provocation (FLIP) were determined. Additionally, ambulatory blood pressure (BP), anthropometry and blood samples were collected. Results The groups displayed similar 24 h BP profiles and anthropometry (all p > .24). Black participants demonstrated a smaller CRAE (158 ± 11 vs. 164 ± 11 MU, p < .001) compared to the white group, whereas CRVE was similar (p = .57). In response to FLIP, artery maximal dilation was greater in the black vs. white group (5.6 ± 2.1 vs. 3.3 ± 1.8%; p < .001). Conclusions Already at a young age, healthy black adults showed narrower retinal arteries relative to the white population. Follow-up studies are underway to show if this will be related to increased risk for hypertension development. The reason for the larger vessel dilation responses to FLIP in the black population is unclear and warrants further investigation. Y1 - 2020 U6 - http://dx.doi.org/10.1016/j.mvr.2019.103937 SN - 0026-2862 VL - 128 IS - Article 103937 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Albanna, W. A1 - Conzen, C. A1 - Weiss, M. A1 - Clusmann, H. A1 - Fuest, M. A1 - Mueller, M. A1 - Brockmann, M.A. A1 - Vilser, W. A1 - Schmidt-Trucksäss, A. A1 - Hoellig, A. A1 - Seiz, M. A1 - Thomé, C. A1 - Kotliar, Konstantin A1 - Schubert, G.A. T1 - Retinal Vessel Analysis (RVA) in the context of subarachnoid hemorrhage: A proof of concept study JF - PLoS ONE N2 - Background Timely detection of impending delayed cerebral ischemia after subarachnoid hemorrhage (SAH) is essential to improve outcome, but poses a diagnostic challenge. Retinal vessels as an embryological part of the intracranial vasculature are easily accessible for analysis and may hold the key to a new and non-invasive monitoring technique. This investigation aims to determine the feasibility of standardized retinal vessel analysis (RVA) in the context of SAH. Methods In a prospective pilot study, we performed RVA in six patients awake and cooperative with SAH in the acute phase (day 2–14) and eight patients at the time of follow-up (mean 4.6±1.7months after SAH), and included 33 age-matched healthy controls. Data was acquired using a manoeuvrable Dynamic Vessel Analyzer (Imedos Systems UG, Jena) for examination of retinal vessel dimension and neurovascular coupling. Results Image quality was satisfactory in the majority of cases (93.3%). In the acute phase after SAH, retinal arteries were significantly dilated when compared to the control group (124.2±4.3MU vs 110.9±11.4MU, p<0.01), a difference that persisted to a lesser extent in the later stage of the disease (122.7±17.2MU, p<0.05). Testing for neurovascular coupling showed a trend towards impaired primary vasodilation and secondary vasoconstriction (p = 0.08, p = 0.09 resp.) initially and partial recovery at the time of follow-up, indicating a relative improvement in a time-dependent fashion. Conclusion RVA is technically feasible in patients with SAH and can detect fluctuations in vessel diameter and autoregulation even in less severely affected patients. Preliminary data suggests potential for RVA as a new and non-invasive tool for advanced SAH monitoring, but clinical relevance and prognostic value will have to be determined in a larger cohort. Y1 - 2016 U6 - http://dx.doi.org/10.1371/journal.pone.0158781 SN - 1932-6203 VL - 11 IS - 7 PB - PLOS CY - San Francisco ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Hanssen, Henner A1 - Eberhardt, Karla A1 - Vilser, Walthard A1 - Schmaderer, Christoph A1 - Halle, Martin A1 - Heemann, Uwe A1 - Baumann, M. T1 - Retinal pulse wave velocity in young male normotensive and mildly hypertensive subjects JF - Microcirculation Y1 - 2013 SN - 1549-8719 N1 - Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.) PB - Wiley CY - Malden ER - TY - JOUR A1 - Ramoshaba, Nthai E. A1 - Huisman, Hugo W. A1 - Lammertyn, Leandi A1 - Kotliar, Konstantin A1 - Schutte, Aletta E. A1 - Smith, Wayne T1 - Retinal microvasculature and masked hypertension in young adults: the African-PREDICT study JF - Hypertension Research N2 - Masked hypertension is known to induce microvascular complications. However, it is unclear whether early microvascular changes are already occurring in young, otherwise healthy adults. We therefore investigated whether retinal microvascular calibers and acute responses to a flicker stimulus are related to masked hypertension. We used the baseline data of 889 participants aged 20–30 years who were taking part in the African Prospective study on the Early Detection and Identification of Cardiovascular Disease and Hypertension. Clinic and 24-h ambulatory blood pressure were measured. The central retinal artery equivalent (CRAE) and central retinal vein equivalent were calculated from fundus images, and retinal vessel dilation was determined in response to flicker light-induced provocation. A smaller CRAE was observed in those with masked hypertension vs. those with normotension (157.1 vs. 161.2 measuring units, P < 0.001). In forward multivariable-adjusted regression analysis, only CRAE was negatively related to masked hypertension [adjusted R² = 0.267, β = −0.097 (95% CI = −0.165; −0.029), P = 0.005], but other retinal microvascular parameters were not associated with masked hypertension. In multivariable logistic regression analyses, masked hypertension [OR = 2.333, (95% CI = 1.316; 4.241), P = 0.004] was associated with a narrower CRAE. In young healthy adults, masked hypertension was associated with retinal arteriolar narrowing, thereby reflecting early microvascular alterations known to predict cardiovascular outcomes in later life. Y1 - 2020 U6 - http://dx.doi.org/10.1038/s41440-020-0487-0 SN - 1348-4214 IS - 43 SP - 1231 EP - 1238 PB - Springer Nature CY - Osaka ER -