TY - JOUR A1 - Murib, Mohammed Sharif A1 - Yeap, Weng-Siang A1 - Martens, Daan A1 - Bienstman, Peter A1 - Ceuninck, Ward de A1 - Grinsven, Bart van A1 - Schöning, Michael Josef A1 - Michiels, Luc A1 - Haenen, Ken A1 - Ameloot, Marcel A1 - Serpengüzel, Ali A1 - Wagner, Patrick T1 - Photonic detection and characterization of DNA using sapphire microspheres JF - Journal of biomedical optics N2 - A microcavity-based deoxyribonucleic acid (DNA) optical biosensor is demonstrated for the first time using synthetic sapphire for the optical cavity. Transmitted and elastic scattering intensity at 1510 nm are analyzed from a sapphire microsphere (radius 500  μm, refractive index 1.77) on an optical fiber half coupler. The 0.43 nm angular mode spacing of the resonances correlates well with the optical size of the sapphire sphere. Probe DNA consisting of a 36-mer fragment was covalently immobilized on a sapphire microsphere and hybridized with a 29-mer target DNA. Whispering gallery modes (WGMs) were monitored before the sapphire was functionalized with DNA and after it was functionalized with single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). The shift in WGMs from the surface modification with DNA was measured and correlated well with the estimated thickness of the add-on DNA layer. It is shown that ssDNA is more uniformly oriented on the sapphire surface than dsDNA. In addition, it is shown that functionalization of the sapphire spherical surface with DNA does not affect the quality factor (Q≈104) of the sapphire microspheres. The use of sapphire is especially interesting because this material is chemically resilient, biocompatible, and widely used for medical implants. Y1 - 2014 U6 - http://dx.doi.org/10.1117/1.JBO.19.9.097006 SN - 1560-2281 (E-Journal); 1083-3668 (Print) VL - 19 IS - 9 SP - 097006 PB - SPIE CY - Bellingham ER - TY - JOUR A1 - Heiligers, Jeannette A1 - Schoutetens, Frederic A1 - Dachwald, Bernd T1 - Photon-sail equilibria in the alpha centauri system JF - Journal of Guidance, Control, and Dynamics Y1 - 2021 U6 - http://dx.doi.org/10.2514/1.G005446 SN - 1533-3884 SN - 0731-5090 SN - 0162-3192 VL - 44 IS - 5 SP - 1053 EP - 1061 ER - TY - JOUR A1 - Mikulics, M. A1 - Marso, M. A1 - Cámara Mayorga, I. A1 - Gusten, R. A1 - Stancek, S. A1 - Michael, E. A. A1 - Schieder, R. A1 - Wolter, M. A1 - Buca, D. A1 - Förster, Arnold A1 - Kordos, P. A1 - Lüth, H. T1 - Photomixers fabricated on nitrogen-ion-implanted GaAs JF - Applied physics letters. 87 (2005) Y1 - 2005 SP - 041106-1 EP - 041106-3 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Schimpf, Axel T1 - Photogrammetric Particle Image Velocimetry / Schimpf, Axel ; Kallweit, Stephan JF - Particle image velocimetry : recent improvements; proceedings of the Europiv 2 Workshop held in Zaragoza, Spain, March 31 - April 1, 2003 / edited by M. Stanislas ... Y1 - 2003 SN - 3-540-21423-2 SP - 295 PB - Springer CY - Berlin ER - TY - JOUR A1 - Ermelenko, Y. A1 - Yoshinobu, T A1 - Mourzina, Y. A1 - Levichev, S. A1 - Furuichi, K. A1 - Vlasov, Y. A1 - Schöning, Michael Josef A1 - Iwasaki, H. T1 - Photocurable membranes for ion-selective light-addressable potentiometric sensors JF - Sensors and Actuators B. 85 (2002), H. 1-2 Y1 - 2002 SN - 0925-4005 SP - 79 EP - 85 ER - TY - JOUR A1 - Hagemann, Hans-Jürgen A1 - Gudat, W. A1 - Kunz, C. T1 - Photoabsorption of alloys of Al with transition metals V, Fe, Ni and Cu and Pr near the Al L₂,₃-edge JF - Solid State Communications N2 - The onset of Al 2p transitions of VAl₃, FeAl, NiAl, NiAl₃, CuAl₂, PrAl₂ and the disordered alloys V-Al (16 at % Al, 28%, 41%), Fe-Al (11%) is shifted up to 1.1 eV. New pronounced structure develops close to the onset which for NiAl agrees with a density of states calculation by Connolly and Johnson. Y1 - 1974 SN - 0038-1098 U6 - http://dx.doi.org/10.1016/0038-1098(74)91165-X VL - 15 IS - 3 SP - 655 EP - 658 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hagemann, Hans-Jürgen A1 - Gudat, W. A1 - Kunz, C. T1 - Photoabsorption coefficient of alloys of Al with transition metals V, Fe, Ni and Cu and Pr from 30 to 150 eV photon energy JF - Physica status solidi b N2 - The absorption coefficient of VAI3, FeAI, NiAI, NiAl2, CuAI2, PrAl2, and of disordered V–AI (16 at% AI, 28%, 41%) and Fe–AI (11%) alloys has been measured in the region of the M₂,₃ absorption of the transition metals and the Labsorption of AI. The strong changes of the AI spectrum in the region of the 100 eV maximum upon alloying are explained as another evidence of the EXAFS (extended X-ray absorption fine structure) nature of these structures. The broad, prominent absorption peaks from the 3p excitations in V and Fe and from the 4d excitations in Pr are influenced only little on allyoing and thus appear to be of atomic origin. The fine structure at the onset of the Pr 4d transitions is identical in the metal and the alloy but differs from that of Pr oxide. The only M₂,₃ edge which is detectably shifted is that of Ni (up to 2.1 eV), whereas the onset of the AI L₂,₃ edge is shifted in all the alloys (up to 1.1 eV). The shifts are interpreted in accordance with X-ray fluorescence and nuclear resonance measurements as changes of the density of states in the valence band of the alloys. Y1 - 1976 SN - 0031-8957 U6 - http://dx.doi.org/10.1002/pssb.2220740211 N1 - weitere ISSN 0370-1972 VL - 74 IS - 2 SP - 507 EP - 521 PB - Wiley-VCH CY - Berlin ER - TY - JOUR A1 - Lagemaat, Miriam W. A1 - Vos, Eline K. A1 - Maas, Marnix C. A1 - Bitz, Andreas A1 - Orzada, Stephan A1 - Uden, Mark J. van A1 - Kobus, Thiele A1 - Heerschap, Arend A1 - Scheenen, Tom W. J. T1 - Phosphorus magnetic resonance spectroscopic imaging at 7 T in patients with prostate cancer JF - Investigative Radiology N2 - Objectives The aim of this study was to identify characteristics of phosphorus (³¹P) spectra of the human prostate and to investigate changes of individual phospholipid metabolites in prostate cancer through in vivo ³¹P magnetic resonance spectroscopic imaging (MRSI) at 7 T. Materials and Methods In this institutional review board–approved study, 15 patients with biopsy-proven prostate cancer underwent T₂-weighted magnetic resonance imaging and 3-dimensional ³¹P MRSI at 7 T. Voxels were selected at the tumor location, in normal-appearing peripheral zone tissue, normal-appearing transition zone tissue, and in the base of the prostate close to the seminal vesicles. Phosphorus metabolite ratios were determined and compared between tissue types. Results Signals of phosphoethanolamine (PE) and phosphocholine (PC) were present and well resolved in most ³¹P spectra in the prostate. Glycerophosphocholine signals were observable in 43% of the voxels in malignant tissue, but in only 10% of the voxels in normal-appearing tissue away from the seminal vesicles. In many spectra, independent of tissue type, 2 peaks resonated in the chemical shift range of inorganic phosphate, possibly representing 2 separate pH compartments. The PC/PE ratio in the seminal vesicles was highly elevated compared with the prostate in 5 patients. A considerable overlap of ³¹P metabolite ratios was found between prostate cancer and normal-appearing prostate tissue, preventing direct discrimination of these tissues. The only 2 patients with high Gleason scores tumors (≥4+5) presented with high PC and glycerophosphocholine levels in their cancer lesions. Conclusions Phosphorus MRSI at 7 T shows distinct features of phospholipid metabolites in the prostate gland and its surrounding structures. In this exploratory study, no differences in ³¹P metabolite ratios were observed between prostate cancer and normal-appearing prostate tissue possibly because of the partial volume effects of small tumor foci in large MRSI voxels. Y1 - 2014 U6 - http://dx.doi.org/10.1097/RLI.0000000000000012 SN - 1536-0210 VL - 49 IS - 5 SP - 363 EP - 372 PB - Lippincott Williams & Wilkins CY - Philadelphia, Pa. ER - TY - JOUR A1 - Hoffschmidt, Bernhard A1 - Riffelmann, K.-J. A1 - Krödel, M. A1 - Rietbrock, P. T1 - PHITREC - pressurized volumetric air receiver for high temperature solar applications / K.-J. Riffelmann ; B. Hofschmidt ... JF - Forschungsbericht : DLR FB. 10 (2001) Y1 - 2001 SN - 0939-2963 N1 - 2. ISSN: 1434-8454 ; Kölner Sonnenkolloquium <5, 2001, Köln> ; Solar thermal power plants and solar chemical processes : advances and perspectives for international cooperation SP - 73 EP - 74 ER - TY - JOUR A1 - Arinkin, Vladimir A1 - Digel, Ilya A1 - Porst, Dariusz A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard T1 - Phenotyping date palm varieties via leaflet cross-sectional imaging and artificial neural network application JF - BMC bioinformatics N2 - Background True date palms (Phoenix dactylifera L.) are impressive trees and have served as an indispensable source of food for mankind in tropical and subtropical countries for centuries. The aim of this study is to differentiate date palm tree varieties by analysing leaflet cross sections with technical/optical methods and artificial neural networks (ANN). Results Fluorescence microscopy images of leaflet cross sections have been taken from a set of five date palm tree cultivars (Hewlat al Jouf, Khlas, Nabot Soltan, Shishi, Um Raheem). After features extraction from images, the obtained data have been fed in a multilayer perceptron ANN with backpropagation learning algorithm. Conclusions Overall, an accurate result in prediction and differentiation of date palm tree cultivars was achieved with average prediction in tenfold cross-validation is 89.1% and reached 100% in one of the best ANN. Y1 - 2014 U6 - http://dx.doi.org/10.1186/1471-2105-15-55 SN - 1471-2105 VL - 15 IS - 55 SP - 1 EP - 8 ER -