TY - CHAP A1 - Pieper, Martin A1 - Wählisch, Georg T1 - Mehrwert von E-Learning durch fächerübergreifenden Einsatz T2 - Teaching is Touching the Future & ePS 2016 - Kompetenzorientiertes Lehren, Lernen und Prüfen Y1 - 2017 SN - 978-3-946017-05-9 SP - 193 EP - 196 PB - UVW Universitätsverlag Webler CY - Bielefeld ER - TY - CHAP A1 - Hebel, Christoph T1 - Mehrwert T2 - Unser Dorf hat Zukunft Y1 - 2014 SP - 6 EP - 7 PB - StädteRegion Aachen CY - Aachen ER - TY - CHAP A1 - Fabo, Sabine A1 - Eisenbeis, Manfred ED - Weber, Hermann T1 - Medienkultur : die mediale Konstruktion von Wirklichkeit T2 - Globalisierung der Zivilisation und überlieferte Kulturen : 28. - 30. April 1995 Y1 - 1995 SN - 3-926288-10-8 N1 - Jahresakademie / Katholischer Akademischer Ausländer-Dienst, KAAD ; [9] PB - Katholischer Akademischer Ausländer-Dienst CY - Bonn ER - TY - CHAP A1 - Bhattarai, Aroj A1 - Staat, Manfred ED - Artmann, Gerhard ED - Temiz Artmann, Aysegül ED - Zhubanova, Azhar A. ED - Digel, Ilya T1 - Mechanics of soft tissue reactions to textile mesh implants T2 - Biological, Physical and Technical Basics of Cell Engineering N2 - For pelvic floor disorders that cannot be treated with non-surgical procedures, minimally invasive surgery has become a more frequent and safer repair procedure. More than 20 million prosthetic meshes are implanted each year worldwide. The simple selection of a single synthetic mesh construction for any level and type of pelvic floor dysfunctions without adopting the design to specific requirements increase the risks for mesh related complications. Adverse events are closely related to chronic foreign body reaction, with enhanced formation of scar tissue around the surgical meshes, manifested as pain, mesh erosion in adjacent structures (with organ tissue cut), mesh shrinkage, mesh rejection and eventually recurrence. Such events, especially scar formation depend on effective porosity of the mesh, which decreases discontinuously at a critical stretch when pore areas decrease making the surgical reconstruction ineffective that further augments the re-operation costs. The extent of fibrotic reaction is increased with higher amount of foreign body material, larger surface, small pore size or with inadequate textile elasticity. Standardized studies of different meshes are essential to evaluate influencing factors for the failure and success of the reconstruction. Measurements of elasticity and tensile strength have to consider the mesh anisotropy as result of the textile structure. An appropriate mesh then should show some integration with limited scar reaction and preserved pores that are filled with local fat tissue. This chapter reviews various tissue reactions to different monofilament mesh implants that are used for incontinence and hernia repairs and study their mechanical behavior. This helps to predict the functional and biological outcomes after tissue reinforcement with meshes and permits further optimization of the meshes for the specific indications to improve the success of the surgical treatment. Y1 - 2018 SN - 978-981-10-7904-7 U6 - http://dx.doi.org/10.1007/978-981-10-7904-7_11 SP - 251 EP - 275 PB - Springer CY - Singapore ER - TY - CHAP A1 - Butenweg, Christoph A1 - Bollenbeck, S. T1 - Mauerwerksbauten unter Erdbebenbelastung T2 - Bauwerke und Erdbeben Y1 - 2003 SN - 3-528-02574-3 SP - 385 EP - 397 PB - Vieweg CY - Wiesbaden ER - TY - CHAP A1 - Butenweg, Christoph A1 - Bollenbeck, S. T1 - Mauerwerksbauten T2 - Bauwerke und Erdbeben / Konstantin Meskouris ; Klaus-G. Hinzen Y1 - 2003 SN - 3-528-02574-3 (Print) ; 978-3-322-96831-9 (E-Book) U6 - http://dx.doi.org/10.1007/978-3-322-96831-9_7 SP - 385 EP - 397 PB - Vieweg + Teubner CY - Wiesbaden ER - TY - CHAP A1 - Geisler, Simon A1 - Pieper, Martin T1 - Mathematik PLuS als E-Book. Kann ein E-Book zur Ingenieursmathematik alle Lerntypen ansprechen? T2 - Das elektronische Schulbuch 2016 Y1 - 2017 SN - 978-3-643-13475-2 SP - 99 EP - 111 PB - LIT Verlag CY - Berlin ER - TY - CHAP A1 - Matcha, Heike A1 - Barczik, Günter ED - Valena, Tomas ED - Avermaete, Tom ED - Vrachliotis, Georg T1 - Mass Diversity: Individualized housing via parametric typology T2 - Structuralism Reloaded? Rule-Based Design in Architecture and Urbanism Y1 - 2011 SN - 978-3-936681-47-5 SP - 354 EP - 358 PB - Edition Axel Menges CY - Fellbach ER - TY - CHAP A1 - Engelmann, Ulrich M. A1 - Shasha, Carolyn A1 - Slabu, Ioana T1 - Magnetic nanoparticle relaxation in biomedical application: focus on simulating nanoparticle heating T2 - Magnetic nanoparticles in human health and medicine Y1 - 2021 SN - 978-1-119-75467-1 SP - 327 EP - 354 PB - Wiley-Blackwell CY - Hoboken, New Jeersey ER - TY - CHAP A1 - Stenger, David A1 - Altherr, Lena A1 - Abel, Dirk T1 - Machine learning and metaheuristics for black-box optimization of product families: a case-study investigating solution quality vs. computational overhead T2 - Operations Research Proceedings 2018 N2 - In product development, numerous design decisions have to be made. Multi-domain virtual prototyping provides a variety of tools to assess technical feasibility of design options, however often requires substantial computational effort for just a single evaluation. A special challenge is therefore the optimal design of product families, which consist of a group of products derived from a common platform. Finding an optimal platform configuration (stating what is shared and what is individually designed for each product) and an optimal design of all products simultaneously leads to a mixed-integer nonlinear black-box optimization model. We present an optimization approach based on metamodels and a metaheuristic. To increase computational efficiency and solution quality, we compare different types of Gaussian process regression metamodels adapted from the domain of machine learning, and combine them with a genetic algorithm. We illustrate our approach on the example of a product family of electrical drives, and investigate the trade-off between solution quality and computational overhead. KW - Product family optimization KW - Mixed-integer nonlinear black-box optimization KW - Engineering optimization KW - Machine learning Y1 - 2019 SN - 978-3-030-18499-5 (Print) SN - 978-3-030-18500-8 (Online) U6 - http://dx.doi.org/10.1007/978-3-030-18500-8_47 SP - 379 EP - 385 PB - Springer CY - Cham ER -