TY  - CHAP
A1  - Koch, Claudia
A1  - Poghossian, Arshak
A1  - Wege, Christina
A1  - Schöning, Michael Josef
ED  - Wege, Christina
T1  - TMV-Based Adapter Templates for Enhanced Enzyme Loading in Biosensor Applications
T2  - Virus-Derived Nanoparticles for Advanced Technologies
N2  - Nanotubular tobacco mosaic virus (TMV) particles and RNA-free lower-order coat protein (CP) aggregates have been employed as enzyme carriers in different diagnostic layouts and compared for their influence on biosensor performance. In the following, we describe a label-free electrochemical biosensor for improved glucose detection by use of TMV adapters and the enzyme glucose oxidase (GOD). A specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CP aggregates was achieved via bioaffinity binding. Glucose sensors with adsorptively immobilized [SA]-GOD, and with [SA]-GOD cross-linked with glutardialdehyde, respectively, were tested in parallel on the same sensor chip. Comparison of these sensors revealed that TMV adapters enhanced the amperometric glucose detection remarkably, conveying highest sensitivity, an extended linear detection range and fastest response times. These results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for applications in biosensorics and biochips. Here, we describe the fabrication and use of amperometric sensor chips combining an array of circular Pt electrodes, their loading with GOD-modified TMV nanotubes (and other GOD immobilization methods), and the subsequent investigations of the sensor performance.
KW  - Tobacco mosaic virus (TMV)
KW  - Coat protein
KW  - Enzyme nanocarrier
KW  - Glucose biosensor
KW  - Glucose oxidase
Y1  - 2018
SN  - 978-1-4939-7808-3
U6  - https://doi.org/10.1007/978-1-4939-7808-3
N1  - Methods in Molecular Biology, vol 1776
SP  - 553
EP  - 568
PB  - Humana Press
CY  - New York, NY
ER  - 
TY  - CHAP
A1  - Pieronek, Lukas
A1  - Kleefeld, Andreas
ED  - Constanda, Christian
ED  - Harris, Paul
T1  - The Method of Fundamental Solutions for Computing Interior Transmission Eigenvalues of Inhomogeneous Media
T2  - Integral Methods in Science and Engineering: Analytic Treatment and Numerical Approximations
N2  - The method of fundamental solutions is applied to the approximate computation of interior transmission eigenvalues for a special class of inhomogeneous media in two dimensions. We give a short approximation analysis accompanied with numerical results that clearly prove practical convenience of our alternative approach.
Y1  - 2019
SN  - 978-3-030-16077-7
U6  - https://doi.org/10.1007/978-3-030-16077-7_28
SP  - 353
EP  - 365
PB  - Birkhäuser
CY  - Cham
ER  - 
TY  - CHAP
A1  - Stollenwerk, Dominik
A1  - Franzke, Till
A1  - Maurer, Florian
A1  - Reinkensmeier, Sebastian
A1  - Kim, Franken
A1  - Tambornino, Philipp
A1  - Haas, Florian
A1  - Rieke, Christian
A1  - Hermanuz, Andreas
A1  - Borchert, Jörg
A1  - Ritz, Thomas
A1  - Sander, Volker
ED  - Proff, Heike
T1  - Smarte Ladesäulen : Netz- und Marktdienliches öffentliches Laden
T2  - Towards the New Normal in Mobility : Technische und betriebswirtschaftliche Aspekte
N2  - Stand 01.01.2022 sind in Deutschland 618.460 elektrisch angetriebene KFZ zugelassen. Insgesamt sind derzeit 48.540.878 KFZ zugelassen, was einer Elektromobilitätsquote von ca. 1,2 % entspricht. Derzeit werden Elektromobile über Ladestationen oder Steckdosen mit dem Stromnetz verbunden und üblicherweise mit der vollen Ladekapazität des Anschlusses aufgeladen, bis das Batteriemanagementsystem des Fahrzeugs abhängig vom Ladezustand der Batterie die Ladeleistung reduziert.
Y1  - 2023
SN  - 978-3-658-39437-0 (Print)
SN  - 978-3-658-39438-7 (Online)
U6  - https://doi.org/10.1007/978-3-658-39438-7_18
SP  - 287
EP  - 304
PB  - Springer Gabler
CY  - Wiesbaden
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Goßmann, Matthias
A1  - Raatschen, Hans-Jürgen
A1  - Temiz Artmann, Aysegül
A1  - Staat, Manfred
T1  - Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM
T2  - Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)
N2  - We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.
Y1  - 2015
SN  - 978-3-319-02534-6 ; 978-3-319-02535-3
SP  - 187
EP  - 212
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Silicon-based chemical and biological field-effect sensors
T2  - Encyclopedia of Sensors. Vol. 9 S - Sk
Y1  - 2006
SN  - 1-58883-065-9
SP  - 463
EP  - 534
PB  - ASP, American Scientific Publ.
CY  - Stevenson Ranch, Calif.
ER  - 
TY  - CHAP
A1  - Tran, N. T.
A1  - Tran, Thanh Ngoc
A1  - Matthies, M. G.
A1  - Stavroulakis, G. E.
A1  - Staat, Manfred
T1  - Shakedown Analysis Under Stochastic Uncertainty by Chance Constrained Programming
T2  - Advances in Direct Methods for Materials and Structures
N2  - In this paper we propose a stochastic programming method to analyse limit and shakedown of structures under uncertainty condition of strength. Based on the duality theory, the shakedown load multiplier formulated by the kinematic theorem is proved actually to be the dual form of the shakedown load multiplier formulated by static theorem. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) with three-node linear triangular elements is used for structural analysis.
Y1  - 2017
SN  - 978-3-319-59810-9
U6  - https://doi.org/10.1007/978-3-319-59810-9_6
SP  - 85
EP  - 103
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - Shakedown analysis of Reissner-Mindlin plates using the edge-based smoothed finite element method
T2  - Direct methods for limit states in structures and materials / Dieter Weichert ; Alan Ponter, ed.
N2  - This paper concerns the development of a primal-dual algorithm for limit and shakedown analysis of Reissner-Mindlin plates made of von Mises material. At each optimization iteration, the lower bound of the shakedown load multiplier is calculated simultaneously with the upper bound using the duality theory. An edge-based smoothed finite element method (ES-FEM) combined with the discrete shear gap (DSG) technique is used to improve the accuracy of the solutions and to avoid the transverse shear locking behaviour. The method not only possesses all inherent features of convergence and accuracy from ES-FEM, but also ensures that the total number of variables in the optimization problem is kept to a minimum compared with the standard finite element formulation. Numerical examples are presented to demonstrate the effectiveness of the present method.
Y1  - 2014
SN  - 978-94-007-6826-0 (Print) 978-94-007-6827-7 (Online)
U6  - https://doi.org/10.1007/978-94-007-6827-7_5
SP  - 101
EP  - 117
PB  - Springer
CY  - Dordrecht [u.a.]
ER  - 
TY  - CHAP
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Razzaque, Mohammed S.
T1  - Role of vitamins in maintaining structure and function of intestinal microbiome
T2  - Comprehensive Gut Microbiota
N2  - The recent advances in microbiology have shed light on understanding the role of vitamins beyond the nutritional range. Vitamins are critical in contributing to healthy biodiversity and maintaining the proper function of gut microbiota. The sharing of vitamins among bacterial populations promotes stability in community composition and diversity; however, this balance becomes disturbed in various pathologies. Here, we overview and analyze the ability of different vitamins to selectively and specifically induce changes in the intestinal microbial community. Some schemes and regularities become visible, which may provide new insights and avenues for therapeutic management and functional optimization of the gut microbiota.
KW  - Vitamin A
KW  - Vitamin B
KW  - Thiamine
KW  - Riboflavin
KW  - Niacin
Y1  - 2022
SN  - 978-0-12-822036-8
U6  - https://doi.org/10.1016/B978-0-12-819265-8.00043-7
SP  - 320
EP  - 334
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Poghossian, Arshak
A1  - Schusser, Sebastian
A1  - Bäcker, M.
A1  - Leinhos, Marcel
A1  - Schöning, Michael Josef
T1  - Real-time in-situ electrical monitoring of the degradation of biopolymers using semiconductor field-effect devices
T2  - Biodegradable biopolymers. Vol. 1
Y1  - 2015
SN  - 978-1-63483-632-6
SP  - 135
EP  - 153
PB  - Nova Science Publ.
CY  - Hauppauge
ER  - 
TY  - CHAP
A1  - Savitskaya, Irina S.
A1  - Kistaubayeva, Aida S.
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Shokatayeva, Dina
A1  - Zhubanova, Azhar Achmet
T1  - Prospective Use of Probiotics Immobilized on Sorbents with Nanostructured Surfaces
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - Activated carbons are known as excellent adsorbents. Their applications include the adsorptive removal of color, odor, taste, undesirable organic and inorganic pollutants from drinking and waste water; air purification in inhabited spaces; purification of many chemicals, pharmaceutical products and many others. This chapter elucidates the role of normal microflora in the maintenance of human health and presents materials on possible clinical displays of microecological infringements and ways of their correction. It presents new developments concerning new probiotics with immobilized Lactobacillus and Bacillus. The chapter considers the mechanisms of the intestine disbacteriosis correction by sorbed probiotics. It demonstrates the advantages and creation prospects of immobilized probiotics developed on the basis of carbonized rice husk. There are great prospects for the development of medical biotechnology due to use of carbon sorbents with a nanostructured surface. Microbial communities form a biocenosis of the biotope and together with the host organism create permanent or temporary ecosystems.
Y1  - 2020
SN  - 978-981-4800-27-3
U6  - https://doi.org/10.1201/9780429428647-12
SP  - 229
EP  - 267
PB  - Jenny Stanford Publishing
CY  - Singapore
ER  -