TY  - JOUR
A1  - Huck, Christina
A1  - Jolly, Christina
A1  - Wagner, Patrick
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - One-chip integrated dual amperometric/field-effect sensor for the detection of dissolved hydrogen
JF  - Procedia Engineering. 25 (2011)
Y1  - 2011
SN  - 1877-7058
N1  - EurosensorsXXV ; Proc. Eurosensors XXV, September 4-7, 2011, Athens, Greece
SP  - 1161
EP  - 1164
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Grotendorst, Johannes
T1  - On calculating the rate of linear convergence of non-linear transformed sequences
JF  - Proceeding SNC '11 Proceedings of the 2011 International Workshop on Symbolic-Numeric Computation
Y1  - 2011
SN  - 978-1-4503-0515-0
SP  - 24
EP  - 33
PB  - ACM
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Jordan, Sabine D.
A1  - Krüger, Markus
A1  - Willmes, Diana M.
A1  - Redemann, Nora
A1  - Wunderlich, F. Thomas
A1  - Brönneke, Hella S.
A1  - Merkwirth, Carsten
A1  - Kashkar, Hamid
A1  - Olkkonen, Vesa M.
A1  - Böttger, Thomas
A1  - Braun, Thomas
A1  - Seibler, Jost
A1  - Brüning, Jens C.
T1  - Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
JF  - Nature Cell Biology
N2  - The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143–145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143–ORP8 pathway as a potential target for the treatment of obesity-associated diabetes.
Y1  - 2011
U6  - http://dx.doi.org/10.1038/ncb2211
SN  - 1465-7392
VL  - 13
IS  - 4
SP  - 434
EP  - 446
PB  - Nature
CY  - New York
ER  - 
TY  - CHAP
A1  - Reindl, Lukas
A1  - Butenweg, Christoph
A1  - Kubalski, Thomas
T1  - Numerical simulation of unreinforced masonry walls subject to dynamic out-of-plane loading
T2  - COMPDYN 2011 : ECCOMAS Thematic Conference ; Proceedings of the 3rd International Conference on Computational Methods in Structural Dynamics and Earthquake Engineering ; 25-28 May, 2011, Corfu, Greece / Eds.: M. Papadrakakis ...
Y1  - 2011
SN  - 978-960-99994-0-3
SP  - 1
EP  - 10
PB  - National Technical Univ. of Athens
CY  - Athen
ER  - 
TY  - JOUR
A1  - Behbahani, Mehdi
A1  - Tran, L.
A1  - Jockenhövel, S.
A1  - Behr, M.
A1  - Mottaghy, K.
T1  - Numerical prediction of thrombocyte reactions for application to a vascular flow model
JF  - British Journal of Surgery
Y1  - 2011
SN  - 1365-2168
N1  - 46th Congress of the European Society for Surgical Research, Aachen, Germany, 25-28 May 2011 ; ESSR Abstracts 2011 ; Oral Sessions OP10-5
VL  - 98
IS  - S5
SP  - S17
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - CHAP
A1  - Taddei, Francesca
A1  - Reindl, Lukas
A1  - Park, Jin
A1  - Butenweg, Christoph
A1  - Karadogan, Faruk
T1  - Numerical investigation of AAC wall panels based on the damage plasticity constitutive law
T2  - Cement, Wapno, Beton ; 2011, 7, Special issue: 5th International Conference on Autoclaved Aerated Concrete 'Securing a sustainable future' to be held at Bydgoszcz to celebrate 60 years of AAC experience in Poland, Bydgoszcz, September 14-17, 2011
Y1  - 2011
SN  - 1425-8129
SP  - 86
EP  - 91
PB  - Stowarzyszenie Producentów Cementu i Wapna
CY  - Krakow
ER  - 
TY  - JOUR
A1  - Reisgen, Uwe
A1  - Schleser, Markus
A1  - Mokrov, Oleg
A1  - Ahmed, Essam
T1  - Numerical and experimental investigation of tensile behavior of laser beam welded TRIP700 steel
JF  - ISIJ international
Y1  - 2011
SN  - 1347-5460 (E-Journal); 0915-1559 (Print)
VL  - Vol. 51
IS  - No. 3
SP  - 429
EP  - 434
PB  - ISIJ
CY  - Tōkyō
ER  - 
TY  - CHAP
A1  - Reisgen, Uwe
A1  - Schleser, Markus
A1  - Scheik, Sven
A1  - Michaeli, Walter
A1  - Grönlund, Oliver
A1  - Neuß, Andreas
A1  - Wunderle, Johannes
A1  - Poprawe, Reinhart
A1  - Rösner, A.
A1  - Bobzin, Kirsten
A1  - Schläfer, Thomas
A1  - Theiß, Sebastian
A1  - Kutschmann, Pia
A1  - Haberstroh, Edmund
A1  - Flock, Dustin
A1  - Bührig-Polaczek, Andreas
A1  - Jakob, M.
ED  - Thoben, Klaus-Dieter
T1  - Novel process chains for the production of plastics/metal-hybrids
T2  - 17th International Conference on Concurrent Enterprising (ICE 2011) : Aachen, Germany, 20 - 22 June 2011
Y1  - 2011
SN  - 978-1-457-70772-8 ; 978-3-943024-05-0
SP  - 596
EP  - 604
PB  - IEEE
CY  - Piscataway, NJ
ER  - 
TY  - JOUR
A1  - Dashevsky, Alexey V.
A1  - Lanzl, Ines M.
A1  - Kotliar, Konstantin
T1  - Non-penetrating intracanalicular partial trabeculectomy via the ostia of Schlemm's canal
JF  - Graefe's Archive for Clinical and Experimental Ophthalmology
Y1  - 2011
SN  - 0721-832x
VL  - 249
IS  - 4
SP  - 565
EP  - 573
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Bung, Daniel B.
T1  - Non-intrusive measuring of air-water flow properties in self-aerated stepped spillway flow
T2  - Balance and uncertainty - water in a changing world :  proceedings of the 34th IAHR world congress ; 33rd Hydrology and Water Resources Symposium ; 10th Conference on Hydraulics in Water Engineering ; 26 June - 1 July 2011, Brisbane, Australia
Y1  - 2011
SN  - 978-0-85825-868-6
SP  - 2380
EP  - 2387
ER  -