TY  - CHAP
A1  - Azat, Seitkhan
A1  - Kerimkulova, Almagul R.
A1  - Mansurov, Zulkhair A.
A1  - Adekenov, Sergazy
A1  - Artmann, Gerhard
T1  - The Use of Fusicoccin as Anticancer Compound
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - The problem of creation and use of sorption materials is of current interest for the practice of the modern medicine and agriculture. Practical importance is production of a biostimulant using a carbon sorbent for a significant increase in productivity, which is very relevant for the regions of Kazakhstan. It is known that a plant phytohormone—fusicoccin—in nanogram concentrations transforms cancer cells to the state of apoptosis. In this regard, there is a scientific practical interest in the development of a highly efficient method for producing fusicoccin from extract of germinated wheat seeds. According to the results of computer modeling, cleaning composite components of fusicoccin using microporous carbon adsorbents not suitable as the size of the molecule of fusicoccin more than micropores and the optimum pore size for purification of constituents of fusicoccin was determined by computer simulation.
Y1  - 2020
SN  - 978-0-429-42864-7
U6  - http://dx.doi.org/10.1201/9780429428647-8
SP  - 149
EP  - 172
PB  - Jenny Stanford Publishing
CY  - New York
ER  - 
TY  - CHAP
A1  - Zhubanova, Azhar A.
A1  - Mansurov, Zulkhair A.
A1  - Digel, Ilya
T1  - Use of Advanced Nanomaterials for Bioremediation of Contaminated Ecosystems
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - This chapter shows that nanomaterials obtained by high-temperature carbonization of inexpensive plant raw material such as rice husk, grape seeds, and walnut shells can serve as a basis for the production of highly efficient microbial drugs, biodestructors, biosorbents, and biocatalysts, which are promising for the remediation of the ecosystem contaminated with heavy and radioactive metals, oil and oil products. A strong interest in engineering zymology is dictated by the necessity to address the issues of monitoring enzymatic processes, treatment, and diagnosis of a number of common human diseases, environmental pollution, quality control of pharmaceuticals and food. Nanomaterials obtained by high-temperature carbonization of cheap plant raw material such as-rice husks, grape seeds and walnut shells, can serve as a basis for creating of highly effective microbial preparations-biodestructors, biosorbents and biocatalysts, which are promising for the use of contaminated ecosystems, and for restoration of human intestine microecology.
Y1  - 2020
SN  - 978-981-4800-27-3
U6  - http://dx.doi.org/10.1201/9780429428647-18
SP  - 353
EP  - 378
PB  - Jenny Stanford Publishing
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Mansurov, Zulkhair A.
A1  - Jandosov, Jakpar
A1  - Chenchik, D.
A1  - Azat, Seitkhan
A1  - Savitskaya, Irina S.
A1  - Kistaubaeva, Aida
A1  - Akimbekov, Nuraly
A1  - Digel, Ilya
A1  - Zhubanova, Azhar Achmet
T1  - Biocomposite Materials Based on Carbonized Rice Husk in Biomedicine and Environmental Applications
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - This chapter describes the prospects for biomedical and environmental engineering applications of heterogeneous materials based on nanostructured carbonized rice husk. Efforts in engineering enzymology are focused on the following directions: development and optimization of immobilization methods leading to novel biotechnological and biomedical applications; construction of biocomposite materials based on individual enzymes, multi-enzyme complexes and whole cells, targeted on realization of specific industrial processes. Molecular biological and biochemical studies on cell adhesion focus predominantly on identification, isolation and structural analysis of attachment-responsible biological molecules and their genetic determinants. The chapter provides a short overview of applications of the biocomposite materials based of nanostructured carbonized adsorbents. It emphasizes that further studies and better understanding of the interactions between CNS and microbial cells are necessary. The future use of living cells as biocatalysts, especially in the environmental field, needs more systematic investigations of the microbial adsorption phenomenon.
Y1  - 2020
SN  - 978-981-4800-27-3
U6  - http://dx.doi.org/10.1201/9780429428647-2
SP  - 3
EP  - 32
PB  - Jenny Stanford Publishing Pte. Ltd.
CY  - Singapore
ER  -