TY  - JOUR
A1  - Karschuck, T. L.
A1  - Filipov, Y.
A1  - Bollella, P.
A1  - Schöning, Michael Josef
A1  - Katz, E.
T1  - Not-XOR (NXOR) logic gate based on an enzyme-catalyzed reaction
JF  - International Journal of Unconventional Computing
N2  - Enzyme-catalyzed reactions have been designed to mimic various Boolean logic gates in the general framework of unconventional biomolecular computing. While some of the logic gates, particularly OR, AND, are easy to realize with biocatalytic reactions and have been reported in numerous publications, some other, like NXOR, are very challenging and have not been realized yet with enzyme reactions. The paper reports on a novel approach to mimicking the NXOR logic gate using the bell-shaped enzyme activity dependent on pH values. Shifting pH from the optimum value to the acidic or basic values by using acid or base inputs (meaning 1,0 and 0,1 inputs) inhibits the enzyme reaction, while keeping the optimum pH (assuming 0,0 and 1,1 input combinations) preserves a high enzyme activity. The challenging part of the present approach is the selection of an enzyme with a well-demonstrated bell-shape activity dependence on the pH value. While many enzymes can satisfy this condition, we selected pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenase as this enzyme has the optimum pH center-located on the pH scale allowing the enzyme activity change by the acidic and basic pH shift from the optimum value corresponding to the highest activity. The present NXOR gate is added to the biomolecular “toolbox” as a new example of Boolean logic gates based on enzyme reactions.
Y1  - 2019
SN  - 1548-7199
VL  - 14
IS  - 3-4
SP  - 235
EP  - 242
PB  - Old City Publishing
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Wilbring, Daniela
A1  - Enning, Manfred
T1  - Stromversorgung auf Güterwagen - Aktuelle Bemühungen zur Standardisierung
JF  - ETR - Eisenbahntechnische Rundschau
Y1  - 2019
SN  - 0013-2845
VL  - 68
IS  - 11
SP  - 64
EP  - 67
PB  - DVV Media Group
CY  - Hamburg
ER  - 
TY  - JOUR
A1  - Valero, Daniel
A1  - Viti, Nicolo
A1  - Gualtieri, Carlo
T1  - Numerical Simulation of Hydraulic Jumps. Part 1: Experimental Data for Modelling Performance Assessment
JF  - Water
Y1  - 2019
U6  - https://doi.org/10.3390/w11010036
SN  - 2073-4441
VL  - 11
IS  - 1
SP  - Art. Nr. 36
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Viti, Nicolo
A1  - Valero, Daniel
A1  - Gualtieri, Carlo
T1  - Numerical Simulation of Hydraulic Jumps. Part 2: Recent Results and Future Outlook
JF  - Water
Y1  - 2019
U6  - https://doi.org/10.3390/w11010028
SN  - 2073-4441
VL  - 11
IS  - 1
SP  - Art. Nr. 28
ER  - 
TY  - JOUR
A1  - Bleilevens, Christian
A1  - Hill, Aileen
A1  - Grzanna, Tim
A1  - Fechter, Tamara
A1  - Bohnen, Melanie
A1  - Weber, Hans-Joachim
A1  - Beckers, Christian
A1  - Borosch, Sebastian
A1  - Zayat, Rashad
A1  - Benstoem, Carin
A1  - Rossaint, Rolf
A1  - Goetzenich, Andreas
T1  - In vitro head-to-head comparison of anticoagulation properties of two heparin brands in a human blood miniature mock loop
JF  - Interactive cardiovascular and thoracic surgery
Y1  - 2019
U6  - https://doi.org/10.1093/icvts/ivy206
SN  - 1569-9285
VL  - 28
IS  - 1
SP  - 120
EP  - 127
ER  - 
TY  - JOUR
A1  - Dotzauer, Martin
A1  - Pfeiffer, Diana
A1  - Lauer, Markus
A1  - Pohl, Marcel
A1  - Mauky, Eric
A1  - Bär, Katharina
A1  - Sonnleitner, Matthias
A1  - Zörner, Wilfried
A1  - Hudde, Jessica
A1  - Schwarz, Björn
A1  - Faßauer, Burkhardt
A1  - Dahmen, Markus
A1  - Rieke, Christian
A1  - Herbert, Johannes
A1  - Thrän, Daniela
T1  - How to measure flexibility – Performance indicators for demand driven power generation from biogas plants
JF  - Renewable Energy
Y1  - 2019
U6  - https://doi.org/10.1016/j.renene.2018.10.021
SN  - 0960-1481
SP  - 135
EP  - 146
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Hüning, Felix
A1  - Hillgärtner, Michael
A1  - Reke, Michael
T1  - Rolling Labs – Teaching Vehicle Electronics from the Beginning
JF  - International Journal of Engineering Pedagogy (iJEP)
Y1  - 2019
U6  - https://doi.org/10.3991/ijep.v9i1.9241
SN  - 2192-4880
VL  - 9
IS  - 1
SP  - 34
EP  - 49
ER  - 
TY  - JOUR
A1  - Arreola, Julio
A1  - Keusgen, Michael
A1  - Schöning, Michael Josef
T1  - Toward an immobilization method for spore-based biosensors in oxidative environment
JF  - Electrochimica Acta
Y1  - 2019
U6  - https://doi.org/10.1016/j.electacta.2019.01.148
VL  - 302
SP  - 394
EP  - 401
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Delaittre, Guillaume
T1  - Telechelic Poly(2-Oxazoline)s
JF  - European Polymer Journal
Y1  - 2019
U6  - https://doi.org/10.1016/j.eurpolymj.2019.109281
SN  - 0014-3057
IS  - In Press, Journal Pre-proof, 109281
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Mennicken, Max
A1  - Peter, Sophia Katharina
A1  - Kaulen, Corinna
A1  - Simon, Ulrich
A1  - Karthäuser, Silvia
T1  - Controlling the Electronic Contact at the Terpyridine/Metal Interface
JF  - The Journal of Physical Chemistry C
Y1  - 2019
U6  - https://doi.org/10.1021/acs.jpcc.9b05865
SN  - 1932-7455
VL  - 123
IS  - 35
SP  - 21367
EP  - 21375
ER  -