TY - JOUR A1 - Öhlschläger, Peter A1 - Osen, Wolfram A1 - Peiler, Tanja A1 - Caldeira, Sandra T1 - A DNA vaccine based on a shuffled E7 oncogene of the human papillomavirus type 16 (HPV 16) induces E7-specific cytotoxic T cells but lacks transforming activity / Osen, Wolfram ; Peiler, Tanja ; Öhlschläger, Peter ; Caldeira, Sandra ; Faath, Stefan ; Mich JF - Vaccine. 19 (2001), H. 20 Y1 - 2001 SN - 0264-410X SP - 4276 EP - 4286 ER - TY - JOUR A1 - Sildatke, Michael A1 - Karwanni, Hendrik A1 - Kraft, Bodo A1 - Zündorf, Albert T1 - A distributed microservice architecture pattern for the automated generation of information extraction pipelines JF - SN Computer Science N2 - Companies often build their businesses based on product information and therefore try to automate the process of information extraction (IE). Since the information source is usually heterogeneous and non-standardized, classic extract, transform, load techniques reach their limits. Hence, companies must implement the newest findings from research to tackle the challenges of process automation. They require a flexible and robust system that is extendable and ensures the optimal processing of the different document types. This paper provides a distributed microservice architecture pattern that enables the automated generation of IE pipelines. Since their optimal design is individual for each input document, the system ensures the ad-hoc generation of pipelines depending on specific document characteristics at runtime. Furthermore, it introduces the automated quality determination of each available pipeline and controls the integration of new microservices based on their impact on the business value. The introduced system enables fast prototyping of the newest approaches from research and supports companies in automating their IE processes. Based on the automated quality determination, it ensures that the generated pipelines always meet defined business requirements when they come into productive use. KW - Architectural design KW - Model-driven software engineering KW - Software and systems modeling KW - Enterprise information systems KW - Information extraction Y1 - 2023 U6 - https://doi.org/10.1007/s42979-023-02256-4 SN - 2661-8907 N1 - Corresponding authors: Michael Sildatke, Hendrik Karwanni IS - 4, Article number: 833 PB - Springer Singapore CY - Singapore ER - TY - JOUR A1 - Sander, Volker A1 - Foster, Ian A1 - Roy, Alain A1 - Winkler, Linda T1 - A differentiated services implementation for high-performance TCP flows JF - Computer Networks. 34 (2000), H. 6 Y1 - 2000 SN - 1389-1286 SP - 915 EP - 929 ER - TY - JOUR A1 - Harder, Jörn T1 - A crystallographic model for the study of local deformation processes in polycrystals JF - International journal of plasticity. 15 (1999), H. 6 Y1 - 1999 SN - 0749-6419 N1 - Online: http://opus.tu-bs.de/opus/volltexte/1999/10/pdf/10_1.pdf SP - 605 EP - 624 ER - TY - JOUR A1 - Bohrn, Ulrich A1 - Mucha, Andreas A1 - Werner, Frederik A1 - Trattner, Barbara A1 - Bäcker, Matthias A1 - Krumbe, Christoph A1 - Schienle, Meinrad A1 - Stütz, Evamaria A1 - Schmitt-Landsiedel, Doris A1 - Fleischer, Maximilian A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - A critical comparison of cell-based sensor systems for the detection of Cr (VI) in aquatic environment JF - Sensors and actuators. B: Chemical Y1 - 2013 SN - 1873-3077 (E-Journal); 0925-4005 (Print) VL - Vol. 182 SP - 58 EP - 65 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Luft, Angela A1 - Bremen, Sebastian A1 - Luft, Nils T1 - A cost/benefit and flexibility evaluation framework for additive technologies in strategic factory planning JF - Processes N2 - There is a growing demand for more flexibility in manufacturing to counter the volatility and unpredictability of the markets and provide more individualization for customers. However, the design and implementation of flexibility within manufacturing systems are costly and only economically viable if applicable to actual demand fluctuations. To this end, companies are considering additive manufacturing (AM) to make production more flexible. This paper develops a conceptual model for the impact quantification of AM on volume and mix flexibility within production systems in the early stages of the factory-planning process. Together with the model, an application guideline is presented to help planners with the flexibility quantification and the factory design process. Following the development of the model and guideline, a case study is presented to indicate the potential impact additive technologies can have on manufacturing flexibility Within the case study, various scenarios with different production system configurations and production programs are analyzed, and the impact of the additive technologies on volume and mix flexibility is calculated. This work will allow factory planners to determine the potential impacts of AM on manufacturing flexibility in an early planning stage and design their production systems accordingly. KW - additive manufacturing KW - factory planning KW - manufacturing flexibility KW - volume flexibility KW - mix flexibility Y1 - 2023 U6 - https://doi.org/10.3390/pr11071968 SN - 2227-9717 VL - 11 IS - 7 PB - MDPI CY - Basel ER - TY - JOUR A1 - Pietsch, Wolfram A1 - Kurbel, Karl T1 - A Cooperative Work Environment for Evolutionary Software Development / Kurbel, K., Pietsch, W. JF - Multi-user interfaces and applications : proceedings of the IFIP WG 8.4 Conference on Multi-User Interfaces and Applications, Heraklion, Crete, Greece, 24 - 26 September, 1990 / ed. by Simon Gibbs ... Y1 - 1990 SN - 0-444-88760-1 N1 - Conference on Multi-User Interfaces and Applications <1990, Hērakleion> SP - 115 EP - 127 PB - North-Holland Publ. CY - Amsterdam [u.a.] ER - TY - JOUR A1 - Haeger, Gerrit A1 - Bongaerts, Johannes A1 - Siegert, Petra T1 - A convenient ninhydrin assay in 96-well format for amino acid-releasing enzymes using an air-stable reagent JF - Analytical Biochemistry N2 - An improved and convenient ninhydrin assay for aminoacylase activity measurements was developed using the commercial EZ Nin™ reagent. Alternative reagents from literature were also evaluated and compared. The addition of DMSO to the reagent enhanced the solubility of Ruhemann's purple (RP). Furthermore, we found that the use of a basic, aqueous buffer enhances stability of RP. An acidic protocol for the quantification of lysine was developed by addition of glacial acetic acid. The assay allows for parallel processing in a 96-well format with measurements microtiter plates. Y1 - 2022 U6 - https://doi.org/10.1016/j.ab.2022.114819 SN - 1096-0309 IS - 624 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Gerling, Ulrich A1 - Pool, M. J. A1 - Predel, Bruno T1 - A contribution to the associate model for binary liquid alloys = Ein Beitrag zum Assoziat-Modell für binäre flüssige Legierungen JF - Zeitschrift für Metallkunde : international journal of materials research and advanced techniques. Bd. 74, H. 9 Y1 - 1983 SN - 0044-3093 ; 0179-4841 SP - 616 EP - 619 ER - TY - JOUR A1 - Breitbach, Gerd A1 - Schubert, F. T1 - A contribution to stress prediction in coatings for gas turbine blades JF - Archive of applied mechanics. 73 (2004), H. 9-10 Y1 - 2004 SN - 0939-1533 N1 - 2. ISSN (Druck-Ausg.): 1432-0681 SP - 682 EP - 689 ER -