TY  - JOUR
A1  - Mikielewicz, Marek
A1  - Kotliar, Konstantin
A1  - Barraquer, Rafael I.
A1  - Michael, Ralph
T1  - Air-pulse corneal applanation signal curve parameters for the characterisation of keratoconus
JF  - British Journal of Ophthalmology (eBJO)
Y1  - 2011
SN  - 1468-2079
VL  - 95
IS  - 6
SP  - 793
EP  - 798
PB  - BMJ Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Morat, Mareike
A1  - Faude, Oliver
A1  - Hanssen, Henner
A1  - Ludyga, Sebastian
A1  - Zacher, Jonas
A1  - Eibl, Angi
A1  - Albracht, Kirsten
A1  - Donath, Lars
T1  - Agility Training to Integratively Promote Neuromuscular, Cognitive, Cardiovascular and Psychosocial Function in Healthy Older Adults: A Study Protocol of a One-Year Randomized-Controlled Trial
JF  - International Journal of Environmental Research and Public Health
N2  - Exercise training effectively mitigates aging-induced health and fitness impairments. Traditional training recommendations for the elderly focus separately on relevant physiological fitness domains, such as balance, flexibility, strength and endurance. Thus, a more holistic and functional training framework is needed. The proposed agility training concept integratively tackles spatial orientation, stop and go, balance and strength. The presented protocol aims at introducing a two-armed, one-year randomized controlled trial, evaluating the effects of this concept on neuromuscular, cardiovascular, cognitive and psychosocial health outcomes in healthy older adults. Eighty-five participants were enrolled in this ongoing trial. Seventy-nine participants completed baseline testing and were block-randomized to the agility training group or the inactive control group. All participants undergo pre- and post-testing with interim assessment after six months. The intervention group currently receives supervised, group-based agility training twice a week over one year, with progressively demanding perceptual, cognitive and physical exercises. Knee extension strength, reactive balance, dual task gait speed and the Agility Challenge for the Elderly (ACE) serve as primary endpoints and neuromuscular, cognitive, cardiovascular, and psychosocial meassures serve as surrogate secondary outcomes. Our protocol promotes a comprehensive exercise training concept for older adults, that might facilitate stakeholders in health and exercise to stimulate relevant health outcomes without relying on excessively time-consuming physical activity recommendations.
KW  - agility
KW  - prevention
KW  - healthy aging
KW  - community dwelling
KW  - psychosocial
Y1  - 2020
U6  - http://dx.doi.org/10.3390/ijerph17061853
SN  - 1660-4601
VL  - 17
IS  - 6
SP  - 1
EP  - 14
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Akimbekov, N. Sh.
A1  - Digel, Ilya
A1  - Zhubanova, A. A.
T1  - Advantages of creation of e-books in training of specialists biologists and biotechnologists
JF  - KazNU Bulletin. Biology series.
N2  - The necessity of e-books as a primary of learning, its opportunities for realization of competence during training biologist and biotechnologist specialists are determined. Definitions and requirements to the e-books, its advantages in comparison with traditional textbooks, and the ways of creation of e-books in the SunRav BookEditor program are considered.
KW  - SunRav BookEditor
KW  - softs
KW  - distance learning
KW  - e-issues
KW  - e-books
Y1  - 2014
SN  - 1563-0218
VL  - 60
IS  - 1
SP  - 249
EP  - 252
PB  - Al-Farabi Kazakh National University
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Müller, Wolfram
A1  - Jung, Alexander
A1  - Ahammer, Helmut
T1  - Advantages and problems of nonlinear methods applied to analyze physiological time signals: human balance control as an example
JF  - Scientific Reports
Y1  - 2017
SN  - 2045-2322
U6  - http://dx.doi.org/10.1038/s41598-017-02665-5
VL  - 7
IS  - Article number 2464
SP  - 1
EP  - 11
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Mandekar, Swati
A1  - Holland, Abigail
A1  - Thielen, Moritz
A1  - Behbahani, Mehdi
A1  - Melnykowycz, Mark
T1  - Advancing towards Ubiquitous EEG, Correlation of In-Ear EEG with Forehead EEG
JF  - Sensors
N2  - Wearable EEG has gained popularity in recent years driven by promising uses outside of clinics and research. The ubiquitous application of continuous EEG requires unobtrusive form-factors that are easily acceptable by the end-users. In this progression, wearable EEG systems have been moving from full scalp to forehead and recently to the ear. The aim of this study is to demonstrate that emerging ear-EEG provides similar impedance and signal properties as established forehead EEG. EEG data using eyes-open and closed alpha paradigm were acquired from ten healthy subjects using generic earpieces fitted with three custom-made electrodes and a forehead electrode (at Fpx) after impedance analysis. Inter-subject variability in in-ear electrode impedance ranged from 20 kΩ to 25 kΩ at 10 Hz. Signal quality was comparable with an SNR of 6 for in-ear and 8 for forehead electrodes. Alpha attenuation was significant during the eyes-open condition in all in-ear electrodes, and it followed the structure of power spectral density plots of forehead electrodes, with the Pearson correlation coefficient of 0.92 between in-ear locations ELE (Left Ear Superior) and ERE (Right Ear Superior) and forehead locations, Fp1 and Fp2, respectively. The results indicate that in-ear EEG is an unobtrusive alternative in terms of impedance, signal properties and information content to established forehead EEG.
KW  - in-ear EEG
KW  - correlation
KW  - forehead EEG
KW  - impedance spectroscopy
KW  - biopotential electrodes
Y1  - 2022
U6  - http://dx.doi.org/10.3390/s22041568
SN  - 1424-8220
VL  - 22
IS  - 4
SP  - 1
EP  - 19
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Zhantlessova, Sirina
A1  - Savitskaya, Irina
A1  - Kistaubayeva, Aida
A1  - Ignatova, Ludmila
A1  - Talipova, Aizhan
A1  - Pogrebnjak, Alexander
A1  - Digel, Ilya
T1  - Advanced “Green” prebiotic composite of bacterial cellulose/pullulan based on synthetic biology-powered microbial coculture strategy
JF  - Polymers
N2  - Bacterial cellulose (BC) is a biopolymer produced by different microorganisms, but in biotechnological practice, Komagataeibacter xylinus is used. The micro- and nanofibrillar structure of BC, which forms many different-sized pores, creates prerequisites for the introduction of other polymers into it, including those synthesized by other microorganisms. The study aims to develop a cocultivation system of BC and prebiotic producers to obtain BC-based composite material with prebiotic activity. In this study, pullulan (PUL) was found to stimulate the growth of the probiotic strain Lactobacillus rhamnosus GG better than the other microbial polysaccharides gellan and xanthan. BC/PUL biocomposite with prebiotic properties was obtained by cocultivation of Komagataeibacter xylinus and Aureobasidium pullulans, BC and PUL producers respectively, on molasses medium. The inclusion of PUL in BC is proved gravimetrically by scanning electron microscopy and by Fourier transformed infrared spectroscopy. Cocultivation demonstrated a composite effect on the aggregation and binding of BC fibers, which led to a significant improvement in mechanical properties. The developed approach for “grafting” of prebiotic activity on BC allows preparation of environmentally friendly composites of better quality.
KW  - coculture
KW  - pullulan
KW  - exopolysaccharides
KW  - prebiotic
KW  - bacterial cellulose
Y1  - 2022
U6  - http://dx.doi.org/10.3390/polym14153224
SN  - 2073-4360
N1  - This article belongs to the Special Issue "Cellulose Based Composites"
VL  - 14
IS  - 15
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Kozhalakova, A. A.
A1  - Zhubanova, Azhar A.
A1  - Mansurov, Z. A.
A1  - Digel, Ilya
A1  - Tazhibayeva, S. M.
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Adsorption of bacterial lipopolysaccharides on carbonized rice shell
JF  - Science of Central Asia (2010)
Y1  - 2010
SP  - 50
EP  - 54
ER  - 
TY  - JOUR
A1  - Akimbekov, N.Sh.
A1  - Digel, Ilya
A1  - O´Heras, C.
A1  - Tastambek, K.T.
A1  - Savitskaya, I.S.
A1  - Ualyeva, P.S.
A1  - Mansurov, Z.A.
A1  - Zhubanova, A.A.
T1  - Adsorption of bacterial lipopolysaccharides on carbonized rice husks obtained in the batch experiments
JF  - Experimental Biology
N2  - The  scope  of  this  study  is  the  measurement  of  endotoxin  adsorption  rate  for  carbonized  rice  husk.  It  showed  good  adsorption properties for LPS. During the batch experiments, several techniques were used and optimized for improving the  material’s  adsorption  behavior.  Also,  with  the  results  obtained  it  was  possible  to  differentiate  the  materials  according to their adsorption capacity and kinetic characteristics.
KW  - surface modification
KW  - adsorption
KW  - carbonized rice husk
KW  - lipopolysaccharide
Y1  - 2014
SN  - 1563-0218
N1  - Original in russischer Sprache
VL  - 60
IS  - 1/2
SP  - 144
EP  - 148
PB  - Al-Farabi Kazakh National University
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Zhubanova, Azhar A.
A1  - Aknazarov, S. K.
A1  - Mansurov, Zulkhair
A1  - Digel, Ilya
A1  - Kozhalakova, A. A.
A1  - Akimbekov, Nuraly Shardarbekovich
A1  - O'Heras, Carlos
A1  - Tazhibayeva, S.
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Adsorption of bacterial Lipopolysaccharides and blood plasma proteins on modified carbonized materials
N2  - Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment.
KW  - Kohlenstofffaser
KW  - Lipopolysaccharide
KW  - nanostrukturierte carbonisierte Pflanzenteile
KW  - lipopolysaccharides
KW  - nanostructured carbonized plant parts
Y1  - 2010
ER  - 
TY  - JOUR
A1  - Akimbekov, N.Sh.
A1  - Digel, Ilya
A1  - O’Heras, C.
A1  - Tastambek, K.T.
A1  - Savitskaya, I.S.
A1  - Ualyeva, P.S.
A1  - Mansurov, Z.A.
A1  - Zhubanova, A.A.
T1  - Adsorption of bacterial lipopol ysaccharides on carbonized ri ce husks obtained in the batch  experiments
JF  - KazNU Bulletin. Biology series
Y1  - 2015
SN  - 1563-0218
VL  - 60
IS  - No 1/2
SP  - 144
EP  - 148
ER  -