TY  - CHAP
A1  - Yoshinobu, Tatsuo
A1  - Miyamoto, Ko-Ichiro
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
ED  - Yamaguchi, Takami
T1  - Miniaturized and high-speed chemical imaging systems
T2  - Nano-Biomedical Engineering 2012. Proceedings of the Tohoku University Global Centre of Excellence Programme, Sakura Hall, Tohoku University, Sendai Japan, 5 – 6 March 2012
Y1  - 2012
U6  - http://dx.doi.org/10.1142/9781848169067_0045
SP  - 386
EP  - 395
PB  - World Scientific
CY  - Singapur
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Trenz, Eva
A1  - Lohmann, Philipp
A1  - Frotscher, Ralf
A1  - Klinge, Uwe
A1  - Tabaza, Ruth
A1  - Kirschner-Hermanns, Ruth
T1  - New measurements to compare soft tissue anchoring systems in pelvic floor surgery
JF  - Journal of Biomedical Materials Research Part B: Applied Biomaterials
N2  - Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment
Y1  - 2012
U6  - http://dx.doi.org/10.1002/jbm.b.32654
SN  - 1552-4981
VL  - 100B
IS  - 4
SP  - 924
EP  - 933
PB  - Wiley
CY  - Hoboken, NJ
ER  - 
TY  - JOUR
A1  - Bergmann, Sandra
A1  - Demuth, Bastian
A1  - Sander, Volker
T1  - A Web Framework for Workflow Submission and Monitoring via UNICORE 6 based on Distributable Scientific Workflow Templates
JF  - UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.)
Y1  - 2011
SN  - 9783893367504
N1  - UNICORE Summit ; (2011 ; 2011.07.07-08 ; Torun) ; Schriften des Forschungszentrums Jülich IAS Series 9
SP  - 45
EP  - 50
PB  - Forschungszentrum Jülich
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Krott, Daniel
A1  - Gerhards, Michael
A1  - Skorupa, Sascha
A1  - Sander, Volker
T1  - NHiLA - Bridging the Gap Between .NET and UNICORE
JF  - UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.)
Y1  - 2011
SN  - 9783893367504
N1  - UNICORE Summit ; (2011 ; 2011.07.07-08 ; Torun) ; Schriften des Forschungszentrums Jülich IAS Series 9
SP  - 77
EP  - 86
PB  - Forschungszentrum Jülich
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Gerhards, M.
A1  - Skorupa, S.
A1  - Sander, Volker
A1  - Pfeiffer, P.
A1  - Belloum, A.
T1  - Towards a security framework for a WS-HumanTask processor
JF  - 7th International Conference on  Network and Service Management (CNSM), 2011 Paris
Y1  - 2011
SN  - 978-3-901882-44-9
SP  - 1
EP  - 5
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Raue, Markus
A1  - Schusser, Sebastian
A1  - Jeitner, C.
A1  - Breuer, L.
A1  - Wagner, P.
A1  - Poghossian, Arshak
A1  - Förster, Arnold
A1  - Mang, Thomas
A1  - Schöning, Michael Josef
T1  - Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films
JF  - Physica Status Solidi  (a)
N2  - Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3–12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off.
Y1  - 2012
U6  - http://dx.doi.org/10.1002/pssa.201100763
SN  - 1862-6319
VL  - 209
IS  - 5
SP  - 839
EP  - 845
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Spelthahn, Heiko
A1  - Schubert, Jürgen
A1  - Schöning, Michael Josef
T1  - Dünnschichtsensoren für die Schwermetallanalytik
JF  - GIT : Labor-Fachzeitschrift
N2  - Die Detektion von Schadstoffen repräsentiert in der Umweltanalytik eine wichtige Aufgabenstellung. Gerade die Abwasser- bzw. Brauchwasseranalytik sowie die Prozesskontrolle haben einen hohen Stellenwert. Siliziumbasierte Dünnschichtsensoren bieten eine kostengünstige Möglichkeit, „online“-Messungen bzw. Vor-Ort-Messungen zeitnah durchzuführen. In dieser Arbeit wird ein potentiometrisches Sensorarray auf der Basis von Chalkogenidgläsern zur Detektion von Schwermetallen in wässrigen Medien vorgestellt.
Y1  - 2012
SN  - 0016-3538
VL  - 56
IS  - 4
SP  - 285
EP  - 287
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Gerhards, Michael
A1  - Sander, Volker
A1  - Belloum, Adam
ED  - Zimmermann, Wolf
ED  - Lee, Yong Woo
ED  - Demchenko, Yuri
T1  - About the flexible Migration of Workflow Tasks to Clouds : Combining on- and off-premise Executions of Applications
T2  - CLOUD COMPUTING 2012 : The Third International Conference on Cloud Computing, GRIDs, and Virtualization ; July 22-27, 2012 - Nice, France
N2  - An increasing number of applications target their executions on specific hardware like general purpose Graphics Processing Units. Some Cloud Computing providers offer this specific hardware so that organizations can rent such resources. However, outsourcing the whole application to the Cloud causes avoidable costs if only some parts of the application benefit from the specific expensive hardware. A partial execution of applications in the Cloud is a tradeoff between costs and efficiency. This paper addresses the demand for a consistent framework that allows for a mixture of on- and off-premise calculations by migrating only specific parts to a Cloud. It uses the concept of workflows to present how individual workflow tasks can be migrated to the Cloud whereas the remaining tasks are executed on-premise.
KW  - Workflow Orchestration
KW  - Workflow
KW  - Grid Computing
KW  - Cloud Service Broker
KW  - Cloud Computing
Y1  - 2012
SN  - 978-1-61208-216-5
SP  - 82
EP  - 87
PB  - IARIA Journals
ER  - 
TY  - JOUR
A1  - Novacek, V.
A1  - Tran, Thanh Ngoc
A1  - Klinge, U.
A1  - Tolba, R. H.
A1  - Staat, Manfred
A1  - Bronson, D. G.
A1  - Miesse, A. M.
A1  - Whiffen, J.
A1  - Turquier, F.
T1  - Finite element modelling of stapled colorectal end-to-end anastomosis : Advantages of variable height stapler design
JF  - Journal of Biomechanics
N2  - The impact of surgical staplers on tissues has been studied mostly in an empirical manner. In this paper, finite element method was used to clarify the mechanics of tissue stapling and associated phenomena. Various stapling modalities and several designs of circular staplers were investigated to evaluate the impact of the device on tissues and mechanical performance of the end-to-end colorectal anastomosis. Numerical simulations demonstrated that a single row of staples is not adequate to resist leakage due to non-linear buckling and opening of the tissue layers between two adjacent staples. Compared to the single staple row configuration, significant increase in stress experienced by the tissue at the inner staple rows was observed in two and three rows designs. On the other hand, adding second and/or third staple row had no effect on strain in the tissue inside the staples. Variable height design with higher staples in outer rows significantly reduced the stresses and strains in outer rows when compared to the same configuration with flat cartridge.
KW  - Variable height stapler design
KW  - Anastomotic leakage
KW  - Finite element modelling
KW  - End-to-end colorectal anastomosis
KW  - Surgical staplers
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.jbiomech.2012.07.021
SN  - 1873-2380
VL  - 45
IS  - 115
SP  - 2693
EP  - 2697
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Nguyen, Nhu Huynh
A1  - Duong, Minh Tuan
A1  - Tran, Thanh Ngoc
A1  - Pham, Phu Tinh
A1  - Grottke, O.
A1  - Tolba, R.
A1  - Staat, Manfred
T1  - Influence of a freeze–thaw cycle on the stress–stretch curves of tissues of porcine abdominal organs
JF  - Journal of Biomechanics
N2  - The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze–thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze–thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines.
KW  - Autolysis
KW  - Decomposition
KW  - Freeze–thaw process
KW  - Spleen
KW  - Liver
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.jbiomech.2012.07.008
SN  - 1873-2380
VL  - 45
IS  - 14
SP  - 2382
EP  - 2386
PB  - Elsevier
CY  - Amsterdam
ER  -