TY - JOUR A1 - Schöning, Michael Josef T1 - Silicon-based biochemical sensors JF - CNI - The Center of Nanoelectronic Systems for Information Technology Y1 - 2003 SP - 165 EP - 170 PB - Foschungszentrum Jülich ER - TY - JOUR A1 - Baroud, G. A1 - Wu, J.Z. A1 - Bohner, M A1 - Sponagel, Stefan A1 - Steffen, T. T1 - How to determine the permeability for cement infiltration into osteoporotic cancellous bone JF - Medical Engineering & Physics. 25 (2003), H. 4 N2 - Cement augmentation is an emerging surgical procedure in which bone cement is used to infiltrate and reinforce osteoporotic vertebrae. Although this infiltration procedure has been widely applied, it is performed empirically and little is known about the flow characteristics of cement during the injection process. We present a theoretical and experimental approach to investigate the intertrabecular bone permeability during the infiltration procedure. The cement permeability was considered to be dependent on time, bone porosity, and cement viscosity in our analysis. In order to determine the time-dependent permeability, ten cancellous bone cores were harvested from osteoporotic vertebrae, infiltrated with acrylic cement at a constant flow rate, and the pressure drop across the cores during the infiltration was measured. The viscosity dependence of the permeability was determined based on published experimental data. The theoretical model for the permeability as a function of bone porosity and time was then fit to the testing data. Our findings suggest that the intertrabecular bone permeability depends strongly on time. For instance, the initial permeability (60.89 mm4/N.s) reduced to approximately 63% of its original value within 18 seconds. This study is the first to analyze cement flow through osteoporotic bone. The theoretical and experimental models provided in this paper are generic. Thus, they can be used to systematically study and optimize the infiltration process for clinical practice. KW - Osteoporose KW - Permeabilität KW - Viskose Strömung KW - Viskosität KW - Vertebroplastie KW - Cement infiltration KW - Vertebroplasty KW - Osteoporosis KW - Permeability KW - Experiment KW - Analysis KW - Viscous flow Y1 - 2003 SN - 1350-4533 SP - 283 EP - 288 ER - TY - JOUR A1 - Kraft, Bodo T1 - Conceptual design mit ArchiCAD 8 : Forschungsprojekt an der RWTH Aachen N2 - Projektbericht in GraphisoftNews - Architektur und Bauen in einer vernetzten Welt 3/2003 4 Seiten KW - CAD KW - CAD KW - Bauingenieurwesen KW - Architektur KW - CAD KW - civil engineering KW - architecture Y1 - 2003 ER - TY - JOUR A1 - Keusgen, M. A1 - Jünger, M. A1 - Krest, I. A1 - Schöning, Michael Josef T1 - Development of a biosensor specific for cysteine sulfoxides JF - Biosensors & Bioelectronics. 18 (2003), H. 5-6 Y1 - 2003 SN - 0956-5663 SP - 805 EP - 812 ER - TY - JOUR A1 - Ermelenko, Y. A1 - Yoshinobu, T. A1 - Mourzina, Y. A1 - Schöning, Michael Josef A1 - Furuichi, K. A1 - Levichev, S. A1 - Vlasov, Y. A1 - Iwasaki, H. T1 - The double K+/Ca2+ sensor based on laser scanned silicon transducer (LSST) for multicomponent analysis JF - Talanta. 59 (2003), H. 4 Y1 - 2003 SN - 0039-9140 SP - 785 EP - 795 ER - TY - JOUR A1 - Wang, J. A1 - Krause, R. A1 - Block, K. A1 - Musameh, M. A1 - Mulchandani, A. A1 - Schöning, Michael Josef T1 - Flow injection amperometric detection of OP nerve agents based on organophosphorus-hydrolase biosensor detector JF - Biosensors & Bioelectronics. 18 (2003), H. 2-3 Y1 - 2003 SN - 0956-5663 SP - 255 EP - 260 ER - TY - JOUR A1 - Keusgen, Michael A1 - Jünger, Martina A1 - Krest, Ingo A1 - Schöning, Michael Josef T1 - Biosensoric detection of the cysteine sulphoxide alliin JF - Sensors and Actuators B. 95 (2003), H. 1-3 Y1 - 2003 SN - 0925-4005 SP - 297 EP - 302 ER - TY - JOUR A1 - Yoshinobu, T. A1 - Schöning, Michael Josef A1 - Otto, R. A1 - Furuichi, K. A1 - Mourzina, Y. A1 - Ermelenko, Y. A1 - Iwasaki, H. T1 - Portable light-addressable potentiometric sensor (LAPS) for multisensor applications JF - Sensors and Actuators B. 95 (2003), H. 1-3 Y1 - 2003 SN - 0925-4005 SP - 352 EP - 356 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Krause, R. A1 - Block, K. A1 - Musahmeh, M. A1 - Mulchandani, A. A1 - Wang, J. T1 - A dual amperometric/potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides JF - Sensors and Actuators B. 95 (2003), H. 1-3 Y1 - 2003 SN - 0925-4005 SP - 291 EP - 296 ER - TY - JOUR A1 - Bressel, A. A1 - Schultze, J.W. A1 - Khan, W. A1 - Wolfaardt, G. M. A1 - Rohns, H.-P. A1 - Irmscher, R. A1 - Schöning, Michael Josef T1 - High resolution gravimetric, optical and electrochemical investigations of microbial biofilm formation in aqueous systems JF - Electrochimica Acta. 48 (2003), H. 20-22 Y1 - 2003 SN - 0013-4686 SP - 3363 EP - 3372 ER -