TY - JOUR A1 - Murib, M. S. A1 - Yeap, W. S. A1 - Eurlings, Y. A1 - Grinsven, B. van A1 - Boyen, H.-G. A1 - Conings, B. A1 - Michiels, L. A1 - Ameloot, Marcel A1 - Carleer, R. A1 - Warmer, J. A1 - Kaul, P. A1 - Haenen, K. A1 - Schöning, Michael Josef A1 - Ceuninck, W. de A1 - Wagner, P. T1 - Heat-transfer based characterization of DNA on synthetic sapphire chips JF - Sensors and Actuators B: Chemical N2 - In this study, we show that synthetic sapphire (Al₂O₃), an established implant material, can also serve as a platform material for biosensors comparable to nanocrystalline diamond. Sapphire chips, beads, and powder were first modified with (3-aminopropyl) triethoxysilane (APTES), followed by succinic anhydride (SA), and finally single-stranded probe DNA was EDC coupled to the functionalized layer. The presence of the APTES-SA layer on sapphire powders was confirmed by thermogravimetric analyis and Fourier-transform infrared spectroscopy. Using planar sapphire chips as substrates and X-ray photoelectron spectroscopy (XPS) as surface-sensitive tool, the sequence of individual layers was analyzed with respect to their chemical state, enabling the quantification of areal densities of the involved molecular units. Fluorescence microscopy was used to demonstrate the hybridization of fluorescently tagged target DNA to the probe DNA, including denaturation- and re-hybridization experiments. Due to its high thermal conductivity, synthetic sapphire is especially suitable as a chip material for the heat-transfer method, which was employed to distinguish complementary- and non-complementary DNA duplexes containing single-nucleotide polymorphisms. These results indicate that it is possible to detect mutations electronically with a chemically resilient and electrically insulating chip material. Y1 - 2016 U6 - https://doi.org/10.1016/j.snb.2016.02.027 SN - 0925-4005 VL - 230 IS - 230 SP - 260 EP - 271 PB - Elsevier CY - Amsterdam ER - TY - BOOK A1 - Stapenhorst, Carolin T1 - Concept : a dialogic instrument in architectural design N2 - Concept - this is a key term in architectural discourse. However, all too often it is used imprecisely or merely for marketing purposes. What is a concept actually? This publication moves between design theory and design practice and follows the history of the definition of concept in architecture, leading to the formulation of a specifically instrumental and operative definition. It bases concept in architecture on its strategic potential in design decision-making processes. In the changing profession of the designing architect, decisions are increasingly made in multidisciplinary groups. Concept can serve as a dialogic instrument in the process, making it possible to process heterogeneous information from a range of spheres of knowledge. The effective presentation of selected information becomes a relevant interface in the design process, which has a significant influence on the quality of the design. Y1 - 2016 SN - 978-3-86859-364-8 PB - Jovis CY - Berlin ER - TY - CHAP A1 - Stapenhorst, Carolin ED - Schmitz, Thomas H. ED - Häußling, Roger ED - Mareis, Claudia ED - Groninger, Hannah T1 - Grids. Projektdokumentationen als Denkinstrument T2 - Manifestationen im Entwurf Y1 - 2016 SN - 978-3-8394-3160-3 U6 - https://doi.org/10.1515/9783839431603-009 SP - 185 EP - 216 PB - Transcript CY - Bielefeld ER - TY - JOUR A1 - Chwallek, Constanze A1 - Frohn, Sandra T1 - Den Mitarbeitern den Rücken stärken JF - Personalwirtschaft N2 - Ein Drittel der Mitarbeiter der Saint-Gobain Glass Deutschland GmbH hat drei Jahre lang regelmäßig seinen Rücken trainiert. Mit Erfolg, wie eine abschließende Evaluation in Zusammenarbeit mit der FH Aachen zeigt. Die Fehltage der Trainingsteilnehmer sind enorm zurückgegangen, während die untrainierten Kollegen weiterhin unter Rückenbeschwerden leiden. Y1 - 2016 SN - 0341-4698 IS - 5 SP - 46 EP - 48 PB - F.A.Z. Business Media CY - Frankfurt a.M. ER - TY - JOUR A1 - Stapenhorst, Carolin A1 - Dutto, Andrea Alberto T1 - Notes on conceptual learning in architecture JF - Cartha - The Form of Form Y1 - 2016 N1 - Auch enthalten in der Buchausgabe "CARTHA – On the Form of Form", ISBN 978-3-03860-070-1, Park Books, 2019 CY - Basel ER - TY - BOOK A1 - Stapenhorst, Carolin T1 - Cento Tavole BT - Referenzen als Werkzeuge des Entwurfs Y1 - 2016 N1 - Katalog zur Ausstellung im Reiff-Museum Aachen, 05/12/16 - 12/12/16 PB - RWTH Aachen CY - Aachen ER - TY - CHAP A1 - Stapenhorst, Carolin ED - Palma, Riccardo ED - Dutto, Andrea Alberto T1 - La Land Art come forma di cartografia applicata / Land Art as a Form of Applied Cartography T2 - Tracciare piani, disegnare carte / Sketching plans, drawing maps Y1 - 2016 SN - 978-88-99982-24-9 SP - 195 PB - Accademia University Press CY - Turin ER - TY - JOUR A1 - Enning, Manfred A1 - Pfaff, Raphael T1 - Digitalisierung bringt mehr Güter auf die Schiene JF - Sonderprojekte ATM/MTZ Y1 - 2016 U6 - https://doi.org/10.1007/s41491-016-0570-7 SN - 2509-4610 VL - 21 IS - 6 (suppl.) SP - 34 EP - 37 PB - Springer Fachmedien CY - Wiesbaden ER - TY - RPRT A1 - Stapenhorst, Carolin A1 - Van Den Bergh, Wim A1 - Goliasch, Simon A1 - Kühnle, Christian A1 - Läufer, Jonas A1 - Ring, Jana A1 - Schmalt, Nicola T1 - Roman traces for cross-border identification T2 - Design Strategies for Transforming Cross-Border Regions N2 - The research group focuses on the characteristics in the land-and cityscapes of the Drielanden-zone, which contribute to generate common identities, as well as on those features that trigger differences and specificities of the adjacent countries that enrich the perception of the zone. In this research, the instruments of cartography and land survey system serve to detect and localize the fragmented appearance of relevant historic elements. These analytic procedures help to develop strategies for infrastructures and processes that gradually initiate local forms of cross-border tourism. The architectural research displays how top-down and bottom-up interventions can be combined in order to guarantee a sustainable use and development of the considered area. KW - Building Culture KW - Archeology KW - Cartography KW - Land Survey and Measurement Systems KW - Infrastructures Y1 - 2016 SP - 5 ER - TY - CHAP A1 - Becker, Sebastian A1 - Höfken, Hans-Wilhelm A1 - Schütz, Philip A1 - Schuba, Marko ED - Schartner, P. T1 - IT-forensische Erkennung modifizierter Android-Apps T2 - Proceedings of DACH Security 2016, Klagenfurt, Austria, September 2016 N2 - Malware auf Smartphones ist ein Problem, dem auch Strafverfolgungsbehörden immer häufiger gegenüberstehen. Insbesondere Telefone, bei denen potentiell schadhafte Apps zu einem finanziellen Schaden geführt haben, finden sich auf den Schreibtischen der Polizei wieder. Dabei müssen die Ermittler möglichst schnell und gezielt erkennen können, ob eine App tatsächlich schadhaft manipuliert wurde, was manipuliert wurde und mit wem die App kommuniziert. Klassische Malware-Erkennungsverfahren helfen zwar bei der generellen Erkennung schadhafter Software, sind aber für die polizeiliche Praxis nicht geeignet. Dieses Paper stellt ein Programm vor, welches gerade die forensischen Fragestellungen berücksichtigt und so für den Einsatz in der Strafverfolgung in Frage kommt. Y1 - 2016 SP - 120 EP - 125 ER -