TY - JOUR A1 - Bialonski, Stephan A1 - Allefeld, C. A1 - Wellmer, J. A1 - Elger, C. A1 - Lehnertz, K. T1 - An approach to identify synchronization clusters within the epileptic network JF - Klinische Neurophysiologie Y1 - 2008 U6 - http://dx.doi.org/10.1055/s-2008-1072881 VL - 39 IS - 1 SP - A79 ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Pedraza, A. M. A1 - Gandhi, D. A1 - Ingebrandt, S. A1 - Moritz, W. A1 - Schöning, Michael Josef T1 - An array of field-effect nanoplate SOI capacitors for (bio-)chemical sensing JF - Biosensors and Bioelectronics. 26 (2011), H. 6 Y1 - 2011 SN - 0956-5663 SP - 3023 EP - 3028 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tran, Thanh Ngoc A1 - Staat, Manfred T1 - An Edge-Based Smoothed Finite Element Method for Primal-Dual Shakedown Analysis of Structures Under Uncertainties JF - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.) Y1 - 2013 SN - 978-94-007-5424-9 SP - 89 EP - 102 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Colombo, Daniele A1 - Drira, Slah A1 - Frotscher, Ralf A1 - Staat, Manfred T1 - An element-based formulation for ES-FEM and FS-FEM models for implementation in standard solid mechanics finite element codes for 2D and 3D static analysis JF - International Journal for Numerical Methods in Engineering N2 - Edge-based and face-based smoothed finite element methods (ES-FEM and FS-FEM, respectively) are modified versions of the finite element method allowing to achieve more accurate results and to reduce sensitivity to mesh distortion, at least for linear elements. These properties make the two methods very attractive. However, their implementation in a standard finite element code is nontrivial because it requires heavy and extensive modifications to the code architecture. In this article, we present an element-based formulation of ES-FEM and FS-FEM methods allowing to implement the two methods in a standard finite element code with no modifications to its architecture. Moreover, the element-based formulation permits to easily manage any type of element, especially in 3D models where, to the best of the authors' knowledge, only tetrahedral elements are used in FS-FEM applications found in the literature. Shape functions for non-simplex 3D elements are proposed in order to apply FS-FEM to any standard finite element. KW - distorted element KW - ES-FEM KW - FS-FEM KW - non-simplex S-FEM elements KW - S-FEM Y1 - 2022 U6 - http://dx.doi.org/10.1002/nme.7126 SN - 1097-0207 VL - 124 IS - 2 SP - 402 EP - 433 PB - Wiley CY - Chichester ER - TY - JOUR A1 - Moseley, Fiona A1 - Halamek, Jan A1 - Kramer, Friederike A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny T1 - An enzyme-based reversible CNOT logic gate realized in a flow system JF - Analyst N2 - An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications. Y1 - 2014 U6 - http://dx.doi.org/10.1039/C4AN00133H SN - 1364-5528 (E-Journal) ; 0003-2654 (Print) VL - 139 IS - 8 SP - 1839 EP - 1842 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Honarvarfard, Elham A1 - Gamella, Maria A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny T1 - An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer JF - Applied Materials Today N2 - An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte–insulator–semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications. KW - Electrolyte–insulator–semiconductor KW - Capacitive field-effect KW - CNOT KW - XOR KW - Enzyme logic gate Y1 - 2017 U6 - http://dx.doi.org/10.1016/j.apmt.2017.08.003 SN - 2352-9407 VL - 9 SP - 266 EP - 270 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tran, Linda A1 - Mottaghy, K. A1 - Arlt-Körfer, Sabine A1 - Waluga, Christian A1 - Behbahani, Mehdi T1 - An experimental study of shear-dependent human platelet adhesion and underlying protein-binding mechanisms in a cylindrical Couette system JF - Biomedizinische Technik Y1 - 2017 U6 - http://dx.doi.org/10.1515/bmt-2015-0034 SN - 0013-5585 VL - 62 IS - 4 SP - 383 EP - 392 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Schütz, S. A1 - Schöning, Michael Josef A1 - Schroth, P. A1 - Weißbecker, B. A1 - Kordos, P. A1 - Lüth, H. A1 - Hummel, Hans E. T1 - An insectbased BioFET as a bioelectronic nose JF - Sensors and Actuators B. 65 (2000), H. 1-3 Y1 - 2000 SN - 0925-4005 SP - 291 EP - 295 ER - TY - JOUR A1 - Schütz, S. A1 - Schöning, Michael Josef A1 - Schroth, P. A1 - Weißbecker, B. A1 - Kordos, P. A1 - Lüth, H. A1 - Hummel, Hans E. T1 - An insectbased BioFET as a bioelectronic nose JF - Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou Y1 - 1998 N1 - International Meeting on Chemical Sensors ; (7, 1998, Beijing) ; International Meeting on Chemical Sensors (IMCS) ; (7 : ; 1998.07.27-30 : ; Beijing) SP - 314 EP - 316 PB - Elsevier CY - Amsterdam [u.a.] ER - TY - JOUR A1 - Staat, Manfred A1 - Kühn, R. A1 - Hauger, W. A1 - Sponagel, Stefan T1 - An Interpretation of Wolff’s Law JF - Biomedizinische Technik. 49 (2004) Y1 - 2004 SN - 0932-4666 N1 - Ergänzungsband 2, Teil 2 SP - 1020 EP - 1021 ER - TY - JOUR A1 - Ziemons, Karl T1 - An investigation of the spin structure of the proton in deep inelastic scattering of polarised muons and polarised protons JF - Nuclear Physics B N2 - The spin asymmetry in deep inelastic scattering of longitudinally polarised muons by longitudinally polarised protons has been measured in the range 0.01<×<0.7. The spin dependent structure function g1(x) for the proton has been determined and, combining the data with earlier SLAC measurements, its integral over x found to be 0.126±0.010(stat.)±0.015(syst.), in disagreement with the Ellis-Jaffe sum rule. Assuming the validity of the Biorken sum rule, this result implies a significant negative value for the integral of g1 for the neutron. These integrals lead to the conclusion, in the naïve quark parton model, that the total quark spin constitutes a rather small fraction of the spin of the nucleon. Results are also presented on the asymmetries in inclusive hadron production which are consistent with the above picture. Y1 - 1989 SN - 0550-3213 N1 - European Muon Collaboration VL - 328 IS - 1 SP - 1 EP - 35 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Schroth, P. A1 - Simonis, A. A1 - Lüth, H. T1 - An ISFET-based penicillin sensor with high sensitivity, low detection limit and long lifetime JF - Sensors and Actuators B. 76 (2001), H. 1-3 Y1 - 2001 SN - 0925-4005 SP - 519 EP - 526 ER - TY - JOUR A1 - Abel, Alexander A1 - Kahmann, Stephanie Lucina A1 - Mellon, Stephen A1 - Staat, Manfred A1 - Jung, Alexander T1 - An open-source tool for the validation of finite element models using three-dimensional full-field measurements JF - Medical Engineering & Physics N2 - Three-dimensional (3D) full-field measurements provide a comprehensive and accurate validation of finite element (FE) models. For the validation, the result of the model and measurements are compared based on two respective point-sets and this requires the point-sets to be registered in one coordinate system. Point-set registration is a non-convex optimization problem that has widely been solved by the ordinary iterative closest point algorithm. However, this approach necessitates a good initialization without which it easily returns a local optimum, i.e. an erroneous registration. The globally optimal iterative closest point (Go-ICP) algorithm has overcome this drawback and forms the basis for the presented open-source tool that can be used for the validation of FE models using 3D full-field measurements. The capability of the tool is demonstrated using an application example from the field of biomechanics. Methodological problems that arise in real-world data and the respective implemented solution approaches are discussed. Y1 - 2020 U6 - http://dx.doi.org/10.1016/j.medengphy.2019.10.015 SN - 1350-4533 VL - 77 SP - 125 EP - 129 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Stulpe, Werner A1 - Gudder, S. A1 - Hagler, J. T1 - An Uncertainty Relation for Joint Position-Momentum Measurements JF - Foundations of Physics Letters. 1 (1988), H. 3 Y1 - 1988 SN - 1572-9524 SP - 287 EP - 292 ER - TY - JOUR A1 - Pham, Phu Tinh A1 - Staat, Manfred T1 - An Upper Bound Algorithm for Limit and Shakedown Analysis of Bounded Linearly Kinematic Hardening Structures JF - Limit State of Materials and Structures : Direct Methods 2. Saxcé, Géry de (Hrsg.) Y1 - 2013 SN - 978-94-007-5424-9 SP - 71 EP - 87 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Grüters, Hugo A1 - Savvidis, E. A1 - Löer, F. A1 - Wiesener, C. H. T1 - Analyse der Beanspruchung des proximalen Femur bei verschiedenen Arten der Belastung mit Hilfe der Finite-Element-Methode / Savvidis, E. ; Löer, F. ; Grüters, Hugo ; Wiesener, C. H. JF - Zeitschrift für Orthopädie und ihre Grenzgebiete. 129 (1991), H. 3 Y1 - 1991 SN - 1615-9586 SP - 268 EP - 277 ER - TY - JOUR A1 - Levers, A. A1 - Staat, Manfred A1 - Laack, Walter van T1 - Analyse der Langzeitwirkung der MBST® KernspinResonanzTherapie bei Gonarthrose T1 - Analysis of the Long-term Effect of the MBST® Nuclear Magnetic Resonance Therapy on Gonarthrosis N2 - Originalausgabe: Orthopädische Praxis Jg. 47. 2011 H. 11; S. 536-543. Mit freundlicher Genehmigung des Verlags Zusammenfassung: Auf der Basis von Patientenabfragen mittels Fragebogen zum Schmerzempfinden und zur Einschränkung bei Aktivitäten des alltäglichen Lebens wird die Langzeitwirkung der MBST® KernspinResonanz-Therapie bei Gonarthrose untersucht. An der Studie nahmen 39 Patienten teil, bei denen die Therapie bis zu vier Jahre zurückliegt. Neben einer Gesamtbetrachtung wird der Erfolg auch in Abhängigkeit von Alter, Geschlecht und sportlicher Aktivität analysiert. Insgesamt weist die Studie auf eine anhaltende Verbesserung des Gesundheitszustands mit zum Teil deutlicher Schmerzlinderung auch noch nach vier Jahren hin, jedoch mit einer leichten Schmerzzunahme gegen Ende des Untersuchungszeitraums von vier Jahren. Eine tendenziell positivere Wirkung bei Frauen, älteren Menschen oder auch sportlich nicht-aktiven Patienten lässt auf eine mögliche Beeinflussung des Erfolgs der Therapie durch (Über-)Belastung im Alltag schließen. Ein zusätzlich positiver Effekt der Therapie auf die Knochendichte ist ebenfalls denkbar, dies bleibt jedoch offen. N2 - Original edition: Orthopädische Praxis Vol. 47. 2011 Issue 11; P. 536-543. On the friendly authority of the publisher. Abstract: Based upon a questionnaire for patient-queries regarding pain-sensation and activity-restrictions during everyday task, the long-term effect of MBST® nuclear magnetic resonance therapy is studied in osteoarthritis of the knee. 39 patients, whose therapy dates back up to four years, participated in the study. In addition to an overall view, the success of this therapy is also analyzed regarding age, gender and physical activities. Overall, the study pointed out a sustained improvement in the patients´ local health-status with a significant pain-relief even after four years, but also with a slight increase in pain towards the end of that four-year period. There tends to be more positive effect on women, on elderly of also on even non-sports-active patients which suggest a possible influence by daily (over)-stressing on the success of the therapy. An additional positive effect of the therapy on bone density is also conceivable, however, this remains open. KW - Kniegelenkarthrose KW - Gonarthrose KW - MBST KW - Arthosetherapie KW - gonarthrosis KW - MBST KW - arthrosis therapy Y1 - 2011 ER - TY - JOUR A1 - Murib, Mohammed S. A1 - Tran, Anh Quang A1 - Ceuninck, Ward de A1 - Schöning, Michael Josef A1 - Nesladek, Milos A1 - Serpengüzel, Ali A1 - Wagner, Patrick T1 - Analysis of an optical biosensor based on elastic light scattering from diamond-, glass-, and sapphire microspheres JF - Physica Status Solidi A N2 - Deoxyribonucleic acid (DNA) and protein recognition are now standard tools in biology. In addition, the special optical properties of microsphere resonators expressed by the high quality factor (Q-factor) of whispering gallery modes (WGMs) or morphology dependent resonances (MDRs) have attracted the attention of the biophotonic community. Microsphere-based biosensors are considered as powerful candidates to achieve label-free recognition of single molecules due to the high sensitivity of their WGMs. When the microsphere surface is modified with biomolecules, the effective refractive index and the effective size of the microsphere change resulting in a resonant wavelength shift. The transverse electric (TE) and the transverse magnetic (TM) elastic light scattering intensity of electromagnetic waves at 600 and 1400 nm are numerically calculated for DNA and unspecific binding of proteins to the microsphere surface. The effect of changing the optical properties was studied for diamond (refractive index 2.34), glass (refractive index 1.50), and sapphire (refractive index 1.75) microspheres with a 50 µm radius. The mode spacing, the linewidth of WGMs, and the shift of resonant wavelength due to the change in radius and refractive index, were analyzed by numerical simulations. Preliminary results of unspecific binding of biomolecules are presented. The calculated shift in WGMs can be used for biomolecules detection. Y1 - 2012 U6 - http://dx.doi.org/10.1002/pssa.201100795 SN - 1862-6319 N1 - Special Issue: "Fundamentals and Applications of Diamond" VL - 209 IS - 9 SP - 1804 EP - 1810 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Heiden, W. A1 - Turek, M. A1 - Schöning, Michael Josef T1 - Analysis of chemical sensor data JF - Proceedings of the 4th Russian-German Workshop "Innovation Information Technologies: Theory and practice" : Ufa, Russia, April 8-13, 2011 / eds. Yupsova, Nafisa ... Y1 - 2011 SN - 978-5-4221-0159-7 SP - 76 EP - 81 PB - State Aviation Technical Univ. CY - Ufa ER - TY - JOUR A1 - Vu, Duc Khoi A1 - Staat, Manfred A1 - Tran, Ich Thinh T1 - Analysis of pressure equipment by application of the primal-dual theory of shakedown JF - Communications in Numerical Methods in Engineering. 23 (2007), H. 3 Y1 - 2007 SN - 1069-8299 SP - 213 EP - 225 ER - TY - JOUR A1 - Levers, A. A1 - Staat, Manfred A1 - Laack, Walter van T1 - Analysis of the long-term effect of the MBST® nuclear magnetic resonance therapy on gonarthrosis JF - Orthopedic Practice Y1 - 2016 VL - 47 IS - 11 SP - 521 EP - 528 ER - TY - JOUR A1 - Ayala, Rafael Ceja A1 - Harris, Isaac A1 - Kleefeld, Andreas A1 - Pallikarakis, Nikolaos T1 - Analysis of the transmission eigenvalue problem with two conductivity parameters JF - Applicable Analysis N2 - In this paper, we provide an analytical study of the transmission eigenvalue problem with two conductivity parameters. We will assume that the underlying physical model is given by the scattering of a plane wave for an isotropic scatterer. In previous studies, this eigenvalue problem was analyzed with one conductive boundary parameter whereas we will consider the case of two parameters. We prove the existence and discreteness of the transmission eigenvalues as well as study the dependence on the physical parameters. We are able to prove monotonicity of the first transmission eigenvalue with respect to the parameters and consider the limiting procedure as the second boundary parameter vanishes. Lastly, we provide extensive numerical experiments to validate the theoretical work. KW - Transmission Eigenvalues KW - Conductive Boundary Condition KW - Inverse Scattering Y1 - 2023 U6 - http://dx.doi.org/10.1080/00036811.2023.2181167 SN - 0003-6811 PB - Taylor & Francis ER - TY - JOUR A1 - Sponagel, Stefan T1 - Analytische Berechnung von Gummi- Metall- Verbindungen JF - Konstruktion : Zeitschrift für Produktentwicklung. 39 (1987), H. 4 Y1 - 1987 SN - 0373-3300 SP - 151 EP - 158 ER - TY - JOUR A1 - Mourzina, Y. G. A1 - Ermelenko, Y. E. A1 - Yoshinobu, T. A1 - Vlasov, Y. A1 - Iwasaki, H. A1 - Schöning, Michael Josef T1 - Anionselective light-addressable potentiometric sensors (LAPS) for the determination of nitrate and suphate ions JF - Sensors and Actuators B. 91 (2003), H. 1-3 Y1 - 2003 SN - 0925-4005 SP - 32 EP - 38 ER - TY - JOUR A1 - Staat, Manfred A1 - Ballmann, J. T1 - Anisotrope Ausbreitung und Fokussierung von Beschleunigungswellen in vorgespannten nichtlinearelastischen Scheiben JF - Wellenfokussierung, Kolloquium des SFB 27, RWTH Aachen Y1 - 1985 SP - 140 EP - 158 CY - Aachen ER - TY - JOUR A1 - Staat, Manfred T1 - Anisotrope Wellenausbreitung in isotropen hyperelastischen Scheiben JF - Zeitschrift für angewandte Mathematik und Mechanik : ZAMM. 67 (1987), H. 4 Y1 - 1987 SN - 0946-8463 SP - T241 EP - T243 ER - TY - JOUR A1 - Savitskaya, I.S. A1 - Kistaubayeva, A.S. A1 - Ignatova, L.V. A1 - Digel, Ilya T1 - Antimicrobial and wound healing properties of a bacterial cellulose based material containing B. subtilis cells JF - Heliyon Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.heliyon.2019.e02592 SN - 2405-8440 VL - 5 IS - 10 SP - Artikelnummer e02592 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Grüters, Hugo A1 - Müller, C. H. T1 - Anwendung der Cosseratschen Kontinuumstheorie auf den ebenen Verbundkörper JF - Zeitschrift für angewandte Mathematik und Mechanik : ZAMM. 61 (1981) Y1 - 1981 SN - 0044-2267 SP - T92 EP - T94 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schultze, J. W. A1 - Schöning, Michael Josef T1 - Application of a (bio-)chemical sensor (ISFET) for the detection of physical parameters in liquids JF - Electrochimica Acta. 48 (2003), H. 20-22 Y1 - 2003 SP - 3289 EP - 3297 ER - TY - JOUR A1 - Pilas, Johanna A1 - Yazici, Y. A1 - Selmer, Thorsten A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Application of a portable multi-analyte biosensor for organic acid determination in silage JF - Sensors N2 - Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at −21 °C, +4 °C, and room temperature) over a period of 140 days. After repeated and regular application, the individual sensing electrodes exhibited the best stability when stored at −21 °C. Furthermore, measurements in silage samples (maize and sugarcane silage) were conducted with the portable biosensor system. Comparison with a conventional photometric technique demonstrated successful employment for rapid monitoring of complex media. Y1 - 2018 U6 - http://dx.doi.org/10.3390/s18051470 SN - 1424-8220 VL - 18 IS - 5 PB - MDPI CY - Basel ER - TY - JOUR A1 - Miyamato, Ko-ichiro A1 - Sakakita, Sakura A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Yoshinobu, Tatsuo T1 - Application of chemical imaging sensor to in-situ pH imaging in the vicinity of a corroding metal surface JF - Electrochimica Acta N2 - The chemical imaging sensor was applied to in-situ pH imaging of the solution in the vicinity of a corroding surface of stainless steel under potentiostatic polarization. A test piece of polished stainless steel was placed on the sensing surface leaving a narrow gap filled with artificial seawater and the stainless steel was corroded under polarization. The pH images obtained during polarization showed correspondence between the region of lower pH and the site of corrosion. It was also found that the pH value in the gap became as low as 2 by polarization, which triggered corrosion. Y1 - 2015 U6 - http://dx.doi.org/10.1016/j.electacta.2015.07.184 SN - 0013-4686 VL - 183 SP - 137 EP - 142 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Poghossian, Arshak A1 - Baade, A. A1 - Emons, H. A1 - Schöning, Michael Josef T1 - Application of ISFET for pH measurements in rain droplets JF - Sensors and Actuators B. 76 (2001), H. 1-3 Y1 - 2001 SN - 0925-4005 SP - 634 EP - 638 ER - TY - JOUR A1 - Yoshinobu, Tatsuo A1 - Moritz, Werner A1 - Finger, Friedhelm A1 - Schöning, Michael Josef ED - Comini, Elisabetta T1 - Application of thin-film amorphous silicon to chemical imaging JF - Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A. Y1 - 2006 SN - 9781558998711 N1 - Materials Research Society symposia proceedings; v. 915 IS - Paper 0910-A-20-01 SP - 1 EP - 10 ER - TY - JOUR A1 - Schütz, S. A1 - Hummel, Hans E. A1 - Schöning, Michael Josef A1 - Schroth, P. A1 - Kordos, P. A1 - Lüth, H. A1 - Zimmermann, S. A1 - Schwarz, A. A1 - Kohl, C.-D. A1 - Koczan, D. T1 - Applications and perspectives of biosensors based on insect olfaction JF - Sensor 99 : proceedings / 9th International Fair and Conference for Sensors, Transducers & Systems, May 18 - 20, 1999, Exhibition Centre Nürnberg/Germany Y1 - 1999 N1 - Internationale Messe mit Kongreß für Sensoren, Meßaufnehmer & Systeme ; (9, 1999, Nürnberg) SP - 99 EP - 104 PB - AMA Service CY - Wunstorf ER - TY - JOUR A1 - Yoshinobu, T. A1 - Yasuhito, U. A1 - Iwasaki, H. A1 - Näther, Niko A1 - Schöning, Michael Josef A1 - Koudelka-Hep, M. T1 - Applications of the light-addressable potentiometric sensor to microfluidic devices JF - Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale]. Y1 - 2004 SN - 88-7621-282-5 N1 - Eurosensors ; (18, 2004, Roma) SP - 434 EP - 437 CY - Roma ER - TY - JOUR A1 - Grotendorst, Johannes T1 - Approximating functions by means of symbolic computation and a general extrapolation method JF - Computer Physics Communications. 59 (1990), H. 2 Y1 - 1990 SN - 0010-4655 SP - 289 EP - 301 ER - TY - JOUR A1 - Figueroa-Miranda, Gabriela A1 - Feng, Lingyan A1 - Shiu, Simon Chi-Chin A1 - Dirkzwager, Roderick Marshall A1 - Cheung, Yee-Wai A1 - Tanner, Julian Alexander A1 - Schöning, Michael Josef A1 - Offenhäusser, Andreas A1 - Mayer, Dirk T1 - Aptamer-based electrochemical biosensor for highly sensitive and selective malaria detection with adjustable dynamic response range and reusability JF - Sensor and Actuators B: Chemical N2 - Malaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a novel aptamer-based electrochemical biosensor (aptasensor) for malaria detection by impedance spectroscopy, through the specific recognition between a highly discriminatory DNA aptamer and its target Plasmodium falciparum lactate dehydrogenase (PfLDH). Interestingly, due to the isoelectric point (pI) of PfLDH, the aptasensor response showed an adjustable detection range based on the different protein net-charge at variable pH environments. The specific aptamer recognition allows sensitive protein detection with an expanded detection range and a low detection limit, as well as a high specificity for PfLDH compared to analogous proteins. The specific feasibility of the aptasensor is further demonstrated by detection of the target PfLDH in human serum. Furthermore, the aptasensor can be easily regenerated and thus applied for multiple usages. The robustness, sensitivity, and reusability of the presented aptasensor make it a promising candidate for point-of-care diagnostic systems. Y1 - 2018 U6 - http://dx.doi.org/10.1016/j.snb.2017.07.117 SN - 0925-4005 VL - 255 IS - P1 SP - 235 EP - 243 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hillen, Walter A1 - Unglauben, F. A1 - Wirtz, G. T1 - Architectures and Modeling of Distributed Image Information Systems. Unglauben, F.; Hillen, W.; Wirtz, G. JF - Proceedings : July 14 - 18, 2002, Orlando, Florida, USA ; [jointly with the 8th International Conference on Information Systems Analysis and Synthesis (ISAS 2002)] / organized by IIIS, International Institute of Informatics and Systemics. Ed. by Nagib Callaos Y1 - 2002 SN - 9800781501 N1 - World Multiconference on Systemics, Cybernetics and Informatics ; (6, 2002, Orlando, Fla.) ; International Conference on Information Systems, Analysis and Synthesis ; (8, 2002, Orlando, Fla.) ; International Institute of Informatics and Systemics ; World Multiconference on Systemics, Cybernetics and Informatics ; (6 : ; 2002.07.14-18 : ; Orlando, Fla.) ; SCI 2002 ; (6 : ; 2002.07.14-18 : ; Orlando, Fla.) ; International Conference on Information Systems Analysis and Synthesis ; (8 : ; 2002.07.14-18 : ; Orlando, Fla.) ; ISAS 2002 ; (8 : ; 2002.07.14-18 : ; Orlando, Fla.) PB - IIIS CY - Orlando, Fla. ER - TY - JOUR A1 - Murgan, Ilina A1 - Beyer, Sonja A1 - Kotliar, Konstantin A1 - Weber, Lutz A1 - Bechtold-Dalla Pozza, Susanne A1 - Dalla Pozza, Robert A1 - Wegner, Aharon A1 - Sitnikova, Diana A1 - Stock, Konrad A1 - Heemann, Uwe A1 - Schmaderer, Christoph A1 - Baumann, M. T1 - Arterial and Retinal Vascular Changes in Hypertensive and Prehypertensive Adolescents JF - American Journal of Hypertension Y1 - 2013 SN - 1941-7225 VL - 26 IS - 3 SP - 400 EP - 408 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Laack, Walter van A1 - Casser, H.-R. T1 - Arthroskopische Behandlung der Osteochondrosis dissecans an der medialen Femurrolle JF - Arthroskopie. 2 (1989), H. 1 Y1 - 1989 SN - 0933-7946 SP - 16 EP - 18 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Turek, M. A1 - Heiden, W. A1 - Riesen, A. A1 - Chhabda, T. A. A1 - Schubert, J. A1 - Krüger, P. A1 - Keusgen, M. T1 - Artificial intelligence/fuzzy logic method for analysis of combined signals from heavy metal chemical sensors JF - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI Y1 - 2009 SN - 0013-4686 SP - 6082 EP - 6088 PB - Elsevier CY - New York ER - TY - JOUR A1 - Hunker, Jan L. A1 - Gossmann, Matthias A1 - Raman, Aravind Hariharan A1 - Linder, Peter T1 - Artificial neural networks in cardiac safety assessment: Classification of chemotherapeutic compound effects on hiPSC-derived cardiomyocyte contractility JF - Journal of Pharmacological and Toxicological Methods Y1 - 2021 U6 - http://dx.doi.org/10.1016/j.vascn.2021.107044 SN - 1056-8719 VL - 111 IS - Article number 107044 PB - Elsevier CY - New York ER - TY - JOUR A1 - Stulpe, Werner T1 - Aspects of the Quantum-Classical Connection Based on Statistical Maps JF - Foundations of Physics Y1 - 2019 U6 - http://dx.doi.org/10.1007/s10701-019-00269-9 VL - 49 IS - 6 SP - 677 EP - 692 PB - Springer CY - Berlin ER - TY - JOUR A1 - Ermolaev, AP A1 - Erichev, VP A1 - Antonov, AA A1 - Grigoryan, GL A1 - Kotliar, Konstantin A1 - Levitsky, YV A1 - Hderi, K A1 - Mazurova, YV T1 - Assessing retinal photosensitivity in patients with central vision impairment using a portable perimeter (a preliminary report) JF - Vestnik oftalmologii Y1 - 2019 U6 - http://dx.doi.org/10.17116/oftalma201913503146 N1 - Abstract in Englisch VL - 135 IS - 3 SP - 46 EP - 54 ER - TY - JOUR A1 - Bogoyavlenskiy, A. P. A1 - Digel, Ilya A1 - Berezin, V. E. T1 - Assessment of dot-blot ELISA sensitivity on membrane sorbent using various peroxidase substrates N2 - The sensitivity of the peroxidase reaction in dot-blot ELISA significantly depends on the substrate. The highest sensitivity is observed using benzidine and diamine- phenol combinations as the substrates due to the reaction of the coupled oxidation (NADI) KW - Enzyme-linked immunosorbent assay KW - Peroxidase KW - ELISA KW - phenols KW - naphtols KW - aromatic amines Y1 - 1997 ER - TY - JOUR A1 - Albracht, Kirsten A1 - Arampatzis, A. A1 - Baltzopoulos, V. T1 - Assessment of muscle volume and physiological cross-sectional area of the human triceps surae muscle in vivo JF - Journal of Biomechanics Y1 - 2008 U6 - http://dx.doi.org/10.1016/j.jbiomech.2008.04.020 SN - 0021-9290 VL - 41 SP - 2211 EP - 2218 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Spillner, Jan A1 - Kopp, Rüdiger A1 - Finocchiaro, Thomas T1 - Assistierte Zirkulation : ein Überblick aus klinischer Sicht = Assisted circulation: an overview from a clinical perspective / Spillner, Jan ; Kopp, Rüdiger ; Finocchiaro, Thomas ; Behbahani, Mehdi ; Rossaint, Rolf ; Steinseifer, Ulrich ; Behr, Marek ; Au JF - Biomedizinische Technik / Biomedical Engineering. 54 (2009), H. 5 Y1 - 2009 SN - 0013-5585 N1 - Printausgabe in der Bereichsbibliothek Jülich vorhanden : 63 Z 471 SP - 255 EP - 267 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Siqueira, José R. Jr. A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Zucolotto, Valtencir A1 - Oliveira, Osvaldo N. Jr. A1 - Schöning, Michael Josef T1 - Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices JF - Physica status solidi (a). 207 (2010), H. 4 Y1 - 2010 SN - 1862-6300 N1 - Special Issue: Engineering of Functional Interfaces EnFI 2009 SP - 781 EP - 786 ER - TY - JOUR A1 - Bialonski, Stephan A1 - Lehnertz, Klaus T1 - Assortative mixing in functional brain networks during epileptic seizures JF - Chaos: An Interdisciplinary Journal of Nonlinear Science Y1 - 2013 U6 - http://dx.doi.org/10.1063/1.4821915 VL - 23 IS - 3 SP - 033139 ER - TY - JOUR A1 - Dikta, Gerhard T1 - Asymptotic Normality Under the Koziol-Green Model JF - Communications in Statistics: Theory and Methods. 24 (1995), H. 6 Y1 - 1995 SN - 0361-0926 SP - 1537 EP - 1549 ER - TY - JOUR A1 - Dikta, Gerhard A1 - Kühlheim, René A1 - Mendonca, Jorge A1 - Una-Alcarez, Jacobo de T1 - Asymptotic representation of presmoothed Kaplan–Meier integrals with covariates in a semiparametric censorship model JF - Journal of Statistical Planning and Inference Y1 - 2015 U6 - http://dx.doi.org/10.1016/j.jspi.2015.12.001 SN - 0378-3758 VL - Vol. 171 SP - 10 EP - 37 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dikta, Gerhard T1 - Asymptotically efficient estimation under semi-parametric random censorship models JF - Journal of multivariate analysis N2 - We study the estimation of some linear functionals which are based on an unknown lifetime distribution. The observations are assumed to be generated under the semi-parametric random censorship model (SRCM), that is, a random censorship model where the conditional expectation of the censoring indicator given the observation belongs to a parametric family. Under this setup a semi-parametric estimator of the survival function was introduced by the author. If the parametric model assumption is correct, it is known that the estimated functional which is based on this semi-parametric estimator is asymptotically at least as efficient as the corresponding one which rests on the nonparametric Kaplan–Meier estimator. In this paper we show that the estimated functional which is based on this semi-parametric estimator is asymptotically efficient with respect to the class of all regular estimators under this semi-parametric model. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.jmva.2013.10.002 SN - 1095-7243 (E-Journal); 0047-259X (Print) VL - 124 SP - 10 EP - 24 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Grotendorst, Johannes A1 - Scott, Tony C. A1 - Aubert-Frécon, Monique A1 - Hadinger, Gisèle T1 - Asymptotically exact calculation of the exchange energies of one-active-electron diatomic ions with the surface integral method / Scott, Tony C. ; Aubert-Frécon, Monique ; Hadinger, Gisèle ; Andrae, Dirk ; Grotendorst, Johannes ; Morgan Ill, John D. JF - Journal of Physics B: Atomic, Molecular and Optival Physics. 37 (2004), H. 22 Y1 - 2004 SN - 0953-4075 SP - 4451 EP - 4469 ER - TY - JOUR A1 - Kleines, H. A1 - Erki, I. A1 - Ziemons, Karl A1 - Zwoll, K. ED - Lehmann, Thomas T1 - ATM- und Multimedia Pilotsystem im Rahmen des Projektes M-FIBRe Aufbau und Erfahrungen JF - Bildverarbeitung für die Medizin : Algorithmen - Systeme - Anwendungen Y1 - 1997 SN - 3-86073-519-5 N1 - Proceedings des Aachener Workshops am 8. u. 9. November 1996 ; PP_001 Posterpräsentation SP - 241 EP - 248 PB - Verl. der. Augustinus-Buchh. CY - Aachen ER - TY - JOUR A1 - Röth, A. A1 - Slabu, I. A1 - Kolvenbach, K. A1 - Engelmann, Ulrich M. A1 - Baumann, M. A1 - Schmitz-Rode, T. A1 - Trahms, L. A1 - Neumann, U. T1 - Aufnahmekinetik von magnetischen Nanopartikeln zur Tumortherapie in humanen Pankreaskarzinomzelllinien JF - Zeitschrift für Gastroenterologie Y1 - 2015 U6 - http://dx.doi.org/10.1055/s-0035-1559529 SN - 1439-7803 VL - 53 IS - 8 SP - KC139 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Schwabedal, Justus T. C. A1 - Sippel, Daniel A1 - Brandt, Moritz D. A1 - Bialonski, Stephan T1 - Automated Classification of Sleep Stages and EEG Artifacts in Mice with Deep Learning N2 - Sleep scoring is a necessary and time-consuming task in sleep studies. In animal models (such as mice) or in humans, automating this tedious process promises to facilitate long-term studies and to promote sleep biology as a data-driven f ield. We introduce a deep neural network model that is able to predict different states of consciousness (Wake, Non-REM, REM) in mice from EEG and EMG recordings with excellent scoring results for out-of-sample data. Predictions are made on epochs of 4 seconds length, and epochs are classified as artifactfree or not. The model architecture draws on recent advances in deep learning and in convolutional neural networks research. In contrast to previous approaches towards automated sleep scoring, our model does not rely on manually defined features of the data but learns predictive features automatically. We expect deep learning models like ours to become widely applied in different fields, automating many repetitive cognitive tasks that were previously difficult to tackle. Y1 - 2018 U6 - http://dx.doi.org/10.48550/arXiv.1809.08443 ER - TY - JOUR A1 - Grieger, Niklas A1 - Schwabedal, Justus T. C. A1 - Wendel, Stefanie A1 - Ritze, Yvonne A1 - Bialonski, Stephan T1 - Automated scoring of pre-REM sleep in mice with deep learning JF - Scientific Reports N2 - Reliable automation of the labor-intensive manual task of scoring animal sleep can facilitate the analysis of long-term sleep studies. In recent years, deep-learning-based systems, which learn optimal features from the data, increased scoring accuracies for the classical sleep stages of Wake, REM, and Non-REM. Meanwhile, it has been recognized that the statistics of transitional stages such as pre-REM, found between Non-REM and REM, may hold additional insight into the physiology of sleep and are now under vivid investigation. We propose a classification system based on a simple neural network architecture that scores the classical stages as well as pre-REM sleep in mice. When restricted to the classical stages, the optimized network showed state-of-the-art classification performance with an out-of-sample F1 score of 0.95 in male C57BL/6J mice. When unrestricted, the network showed lower F1 scores on pre-REM (0.5) compared to the classical stages. The result is comparable to previous attempts to score transitional stages in other species such as transition sleep in rats or N1 sleep in humans. Nevertheless, we observed that the sequence of predictions including pre-REM typically transitioned from Non-REM to REM reflecting sleep dynamics observed by human scorers. Our findings provide further evidence for the difficulty of scoring transitional sleep stages, likely because such stages of sleep are under-represented in typical data sets or show large inter-scorer variability. We further provide our source code and an online platform to run predictions with our trained network. Y1 - 2021 U6 - http://dx.doi.org/10.1038/s41598-021-91286-0 SN - 2045-2322 N1 - Corresponding author: Stephan Bialonski VL - 11 IS - Art. 12245 PB - Springer Nature CY - London ER - TY - JOUR A1 - Poghossian, Arshak A1 - Wagner, H. A1 - Schöning, Michael Josef T1 - Automatisiertes „wafer level“-Testsystem zur Charakterisierung von siliziumbasierten Chemo- und Biosensoren JF - Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA) Y1 - 2010 SN - 978-3-8007-3260-9 N1 - Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik SP - 89 EP - 92 PB - VDE Verlag CY - Berlin ER - TY - JOUR A1 - Pogorelova, Natalia A1 - Rogachev, Evgeniy A1 - Digel, Ilya A1 - Chernigova, Svetlana A1 - Nardin, Dmitry T1 - Bacterial Cellulose Nanocomposites: Morphology and Mechanical Properties JF - Materials N2 - Bacterial cellulose (BC) is a promising material for biomedical applications due to its unique properties such as high mechanical strength and biocompatibility. This article describes the microbiological synthesis, modification, and characterization of the obtained BC-nanocomposites originating from symbiotic consortium Medusomyces gisevii. Two BC-modifications have been obtained: BC-Ag and BC-calcium phosphate (BC-Ca3(PO4)2). Structure and physicochemical properties of the BC and its modifications were investigated by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), atomic force microscopy (AFM), and infrared Fourier spectroscopy as well as by measurements of mechanical and water holding/absorbing capacities. Topographic analysis of the surface revealed multicomponent thick fibrils (150–160 nm in diameter and about 15 µm in length) constituted by 50–60 nm nanofibrils weaved into a left-hand helix. Distinctive features of Ca-phosphate-modified BC samples were (a) the presence of 500–700 nm entanglements and (b) inclusions of Ca3(PO4)2 crystals. The samples impregnated with Ag nanoparticles exhibited numerous roundish inclusions, about 110 nm in diameter. The boundaries between the organic and inorganic phases were very distinct in both cases. The Ag-modified samples also showed a prominent waving pattern in the packing of nanofibrils. The obtained BC gel films possessed water-holding capacity of about 62.35 g/g. However, the dried (to a constant mass) BC-films later exhibited a low water absorption capacity (3.82 g/g). It was found that decellularized BC samples had 2.4 times larger Young’s modulus and 2.2 times greater tensile strength as compared to dehydrated native BC films. We presume that this was caused by molecular compaction of the BC structure. Y1 - 2020 SN - 1996-1944 U6 - http://dx.doi.org/10.3390/ma13122849 VL - 13 IS - 12 SP - 1 EP - 16 PB - MDPI CY - Basel ER - TY - JOUR A1 - Digel, Ilya A1 - Akimbekov, Nuraly A1 - Rogachev, Evgeniy A1 - Pogorelova, Natalia T1 - Bacterial cellulose produced by Medusomyces gisevii on glucose and sucrose: biosynthesis and structural properties JF - Cellulose N2 - In this work, the effects of carbon sources and culture media on the production and structural properties of bacterial cellulose (BC) synthesized by Medusomyces gisevii have been studied. The culture medium was composed of different initial concentrations of glucose or sucrose dissolved in 0.4% extract of plain green tea. Parameters of the culture media (titratable acidity, substrate conversion degree etc.) were monitored daily for 20 days of cultivation. The BC pellicles produced on different carbon sources were characterized in terms of biomass yield, crystallinity and morphology by field emission scanning electron microscopy (FE-SEM), atomic force microscopy and X-ray diffraction. Our results showed that Medusomyces gisevii had higher BC yields in media with sugar concentrations close to 10 g L−1 after a 18–20 days incubation period. Glucose in general lead to a higher BC yield (173 g L−1) compared to sucrose (163.5 g L−1). The BC crystallinity degree and surface roughness were higher in the samples synthetized from sucrose. Obtained FE-SEM micrographs show that the BC pellicles synthesized in the sucrose media contained densely packed tangles of cellulose fibrils whereas the BC produced in the glucose media displayed rather linear geometry of the BC fibrils without noticeable aggregates. KW - Bacterial cellulose KW - Medusomyces gisevi KW - Carbon sources KW - Culture media KW - Cellulose nanostructure Y1 - 2023 U6 - http://dx.doi.org/10.1007/s10570-023-05592-z SN - 1572-882X (Online) SN - 0969-0239 (Print) N1 - Corresponding author: Ilya Digel PB - Springer Science + Business Media CY - Dordrecht ER - TY - JOUR A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Nishikawa, K. A1 - Cook, M. T1 - Bactericidal effects of plasma-generated cluster ions JF - Medical and Biological Engineering and Computing. 43 (2005), H. 6 Y1 - 2005 SN - 1741-0444 SP - 800 EP - 807 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Bochev, B. A1 - Lieder, R. M. A1 - Morek, T. T1 - Band crossing and blocking in side bands of ¹⁸⁰,¹⁸² Os JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1982) Y1 - 1982 N1 - Verhandlungen der Deutschen Physikalischen Gesellschaft ; 1982=6.R.17,6 SP - 1273 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Neskakis, A A1 - Gono, Y. T1 - Band structure in ¹⁹⁰,¹⁹² Au JF - Frühjahrstagung ... des Fachausschusses Kernphysik und Hochenergiephysik der DPG (Sektion A: Kernphysik) / Deutsche Physikalische Gesellschaft (1978) Y1 - 1978 SP - 796 PB - Physik-Verlag CY - Weinheim ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Neskakis, A A1 - Gono, Y. T1 - Band structure in ¹⁹⁰,¹⁹² Au JF - Annual report 1977 / Institut für Kernphysik Kernforschungsanlage Jülich Y1 - 1978 N1 - Spezielle Berichte der Kernforschungsanlage Jülich ; 15 SP - 46 EP - 47 PB - Verlag des Forschungszentrums Jülich CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Neskakis, A. A1 - Beuscher, H. A1 - Haenni, D. R. T1 - Band structure in ¹⁹⁴ Au JF - Annual report 1978 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 36) Y1 - 1979 SP - 36 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Staat, Manfred T1 - Basis Reduction for the Shakedown Problem for Bounded Kinematic Hardening Material N2 - Limit and shakedown analysis are effective methods for assessing the load carrying capacity of a given structure. The elasto–plastic behavior of the structure subjected to loads varying in a given load domain is characterized by the shakedown load factor, defined as the maximum factor which satisfies the sufficient conditions stated in the corresponding static shakedown theorem. The finite element dicretization of the problem may lead to very large convex optimization. For the effective solution a basis reduction method has been developed that makes use of the special problem structure for perfectly plastic material. The paper proposes a modified basis reduction method for direct application to the two-surface plasticity model of bounded kinematic hardening material. The considered numerical examples show an enlargement of the load carrying capacity due to bounded hardening. KW - Finite-Elemente-Methode KW - Einspielen KW - Basis Reduktion KW - konvexe Optimierung KW - FEM KW - Druckgeräte KW - Basis reduction KW - Convex optimization KW - FEM KW - Shakedown analysis Y1 - 2000 ER - TY - JOUR A1 - Buniatyan, V. A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Aroutiounian, V. M. A1 - Schöning, Michael Josef T1 - BaxSr1-x TiO3/pc-Si heterojunction JF - Armenian journal of physics Y1 - 2013 SN - 1829-1171 VL - 6 IS - 4 SP - 177 EP - 187 PB - National Academy of Sciences of Armenia CY - Yerevan ER - TY - JOUR A1 - Buniatyan, V. A1 - Huck, Christina A1 - Poghossian, Arshak A1 - Aroutiounian, V. M. A1 - Schöning, Michael Josef T1 - BaxSr1-x TiO3/pc-Si heterojunction capacitance JF - Armenian journal of physics Y1 - 2013 SN - 1829-1171 VL - 6 IS - 4 SP - 188 EP - 197 PB - National Academy of Sciences of Armenia CY - Yerevan ER - TY - JOUR A1 - Laack, Walter van A1 - Refisch, A. T1 - Beeinflussen Beinhalter die Knieseitenbandstabilität bei der Arthroskopie? JF - Orthopädische Praxis. 23 (1987) Y1 - 1987 SN - 0030-588x SP - 434 ER - TY - JOUR A1 - Grüters, Hugo T1 - Berechnung des Spannungszustandes in homogenen Scheiben aus anisotrop-elastischem Material JF - Zeitschrift für angewandte Mathematik und Mechanik : ZAMM Y1 - 1972 SN - 0044-2267 U6 - http://dx.doi.org/10.1002/zamm.19720521105 VL - 52 IS - 11 SP - T127 EP - T128 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Grüters, Hugo A1 - Hiemenz, C. T1 - Berechnung des Verzugs und der Schwindung von Profilen aus PUR-Strukturschaumstoff. Kriterien zur Herstellung von verzugsfreien Profilen JF - Kunststoffe. 70 (1980), H. 2 Y1 - 1980 SN - 0023-5563 SP - 102 EP - 107 ER - TY - JOUR A1 - Grüters, Hugo A1 - Hiemenz, C. T1 - Berechnung des Verzugs und der Schwindung von PUR-Strukturschaumplatten JF - Kunststoffe. 70 (1980), H. 4 Y1 - 1980 SN - 0023-5563 SP - 228 EP - 233 ER - TY - JOUR A1 - Werner, Frederik A1 - Groebel, Simone A1 - Schuhmacher, K. A1 - Spelthahn, Heiko A1 - Wagner, Torsten A1 - Selmer, Thorsten A1 - Baumann, Marcus A1 - Schöning, Michael Josef T1 - Bestimmung der metabolischen Aktivität von Mikroorganismen während des Biogasbildungsprozesses JF - 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.] Y1 - 2009 SN - 978-3-941298-44-6 N1 - Dresdner Sensor-Symposium ; (9, 2009, Dresden) SP - 201 EP - 204 PB - TUDpress CY - Dresden ER - TY - JOUR A1 - Reißel, Martin A1 - Jung, L. A1 - Köttgen, V. A1 - Mäscher, G. T1 - Betriebsfestigkeit eines PKW-Schwenklagers / Jung, L. ; Köttgen, V. ; Mäscher, G. ; Reißel, M. ; Zhang, G. JF - Materialprüfung : MP. 40 (1998), H. 10 Y1 - 1998 SN - 0025-5300 SP - 388 EP - 393 ER - TY - JOUR A1 - Reißel, Martin A1 - Bitsch, G. A1 - Kießling, A. A1 - Mawick, G. T1 - Betriebsfestigkeitsanalyse von Türschließvorgängen auf der Basis transienter FEM Simulationen / Bitsch, G. ; Kießling, A. ; Mawick, G. ; Reißel, M. ; Tokar, G. ; Wirth, C. JF - LS DYNA Forum, 2002; V25 Y1 - 2002 SP - 1 EP - 10 ER - TY - JOUR A1 - Ziemons, Karl A1 - Bruyndonckx, P. A1 - Perez, J. M. A1 - Pietrzyk, U. A1 - Rato, P. A1 - Tavernier, S. T1 - Beyond ClearPET: Next Aims JF - 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro Symposium Proceedings ISBI 2008 N2 - The CRYSTAL CLEAR collaboration, in short CCC, is a consortium of 12 academic institutions, mainly from Europe, joining efforts in the area of developing instrumentation for nuclear medicine and medical imaging. In the framework of the CCC a high performance small animal PET system, called ClearPET, was developed by using new technologies in electronics and crystals in a phoswich arrangement combining two types of lutetium- based scintillator materials: LSO:Ce and LuYAP:Ce. Our next aim will be the development of hybrid image systems. Hybrid MR-PET imaging has many unique advantages for brain research. This has sparked a new research line within CCC for the development of novel MR-PET compatible technologies. MRI is not as sensitive as PET but PET has poorer spatial resolution than MRI. Two major advantages of PET are sensitivity and its ability to acquire metabolic information. To assess these innovations, the development of a 9.4T hybrid animal MR-PET scanner is proposed based on an existing 9.4T MR scanner that will be adapted to enable simultaneous acquisition of MR and PET data using cutting- edge technology for both MR and PET. Y1 - 2008 SN - 978-1-4244-2003-2 SP - 1421 EP - 1424 ER - TY - JOUR A1 - Hillen, Walter T1 - Bildrestauration in der digitalen Radiographie mit Hilfe parallel arbeitender Signalprozessoren JF - Parallele Datenverarbeitung : Entwurfsmethoden, Bildverarbeitung, Simulation ; Workshop der Arbeitsgemeinschaft "Parallelverarbeitung an Fachhochschulen in NRW" am 19.6.1998 in Bochum / Jörg Krone ... (Hrsg.) Y1 - 1998 SN - 3-18-355310-4 N1 - Fortschritt-Berichte VDI : Reihe 10, Informatik, Kommunikationstechnik ; 553 SP - 78 EP - 87 PB - VDI-Verl. CY - Düsseldorf ER - TY - JOUR A1 - Mansurov, Z. A1 - Digel, Ilya A1 - Biisenbaev, M. A1 - Savistkaya, I. A1 - Kistaubaeva, A. A1 - Akimbekov, N. A1 - Zhubanova, A. T1 - Bio-composite material on the basis of carbonized rice husk in biomedicine and environmental applications JF - Eurasian Chemico-Technological Journal Y1 - 2012 U6 - http://dx.doi.org/10.18321/ectj105 SN - 2522-4867 VL - 14 IS - 2 SP - 115 EP - 131 PB - Institute of Combustion Problems CY - Almaty ER - TY - JOUR A1 - Uysal, Karya A1 - Creutz, Till A1 - Firat, Ipek Seda A1 - Artmann, Gerhard A1 - Teusch, Nicole A1 - Temiz Artmann, Aysegül T1 - Bio-functionalized ultra-thin, large-area and waterproof silicone membranes for biomechanical cellular loading and compliance experiments JF - Polymers N2 - Biocompatibility, flexibility and durability make polydimethylsiloxane (PDMS) membranes top candidates in biomedical applications. CellDrum technology uses large area, <10 µm thin membranes as mechanical stress sensors of thin cell layers. For this to be successful, the properties (thickness, temperature, dust, wrinkles, etc.) must be precisely controlled. The following parameters of membrane fabrication by means of the Floating-on-Water (FoW) method were investigated: (1) PDMS volume, (2) ambient temperature, (3) membrane deflection and (4) membrane mechanical compliance. Significant differences were found between all PDMS volumes and thicknesses tested (p < 0.01). They also differed from the calculated values. At room temperatures between 22 and 26 °C, significant differences in average thickness values were found, as well as a continuous decrease in thicknesses within a 4 °C temperature elevation. No correlation was found between the membrane thickness groups (between 3–4 µm) in terms of deflection and compliance. We successfully present a fabrication method for thin bio-functionalized membranes in conjunction with a four-step quality management system. The results highlight the importance of tight regulation of production parameters through quality control. The use of membranes described here could also become the basis for material testing on thin, viscous layers such as polymers, dyes and adhesives, which goes far beyond biological applications. Y1 - 2022 SN - 2073-4360 VL - 14 IS - 11 SP - 2213 PB - MDPI CY - Basel ER - TY - JOUR A1 - Kramer, Friederike A1 - Halamkova, Lenka A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny A1 - Halamek, Jan T1 - Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American JF - The analyst. August 2013 Y1 - 2013 SN - 1364-5528 (E-Journal); 0003-2654 (Print) VL - Vol. 138 SP - 6251 EP - 6257 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Lüth, H. A1 - Thust, M. A1 - Steffen, A. A1 - Kordos, P. A1 - Schöning, Michael Josef T1 - Biochemical sensors with structured and porous silicon capacitors JF - Materials Science and Engineering B. 69-70 (2000) Y1 - 2000 SN - 0921-5107 SP - 104 EP - 108 ER - TY - JOUR A1 - Akimbekov, N. S. A1 - Digel, Ilya A1 - Tastambek, K. T. A1 - Zhubanova, A. A. T1 - Biocompatibility of carbonized rice husk with a rat heart cells line H9c2 JF - Experimental Biology Y1 - 2013 SN - 1563-0218 N1 - Original in russischer Sprache VL - 59 IS - 3/1 SP - 23 EP - 25 ER - TY - JOUR A1 - Schroth, P. A1 - Weißbecker, B. A1 - Schütz, S. A1 - Ecken, H. A1 - Yoshinobu, T. A1 - Lüth, H. A1 - Schöning, Michael Josef T1 - Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices JF - Lecture Notes of the ICB Seminars Y1 - 2002 SP - 28 EP - 42 PB - MCB CY - Warsaw ER - TY - JOUR A1 - Schroth, P. A1 - Weißbecker, B. A1 - Schütz, S. A1 - Ecken, H. A1 - Yoshinobu, T. A1 - Lüth, H. A1 - Schöning, Michael Josef T1 - Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices JF - Biocybernetics and Biomedical Engineering. 21 (2001), H. 3 Y1 - 2001 SN - 0208-5216 SP - 27 EP - 42 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - BioFEDs (field-effect devices) : State-of-the-art and new directions JF - Electroanalysis Y1 - 2006 U6 - http://dx.doi.org/10.1002/elan.200603609 SN - 1521-4109 VL - 18 IS - 19-20 SP - 1893 EP - 1900 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Rusowicz, Andreas A1 - Nguyen, Christoph A1 - Nour, Youness T1 - Biologische Auswertung von verschiedenen Bestrahlungsplanvarianten für Zielvolumina im Abdomenbereich mit einem hauseigenen Computerprogramm Y1 - 2007 N1 - TH.SS.A3.04 ; Dreiländertagung Medizinphysik 2007. Vom 25.-28. September 2007. Universität Bern, Schweiz. Abteilung für Medizinische Strahlenphysik SP - 6 EP - 7 ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Koshitz, I. N. A1 - Svetlowa, O. V. A1 - Makarov, F. N. T1 - Biomechanical analysis of traditional and contemporary conceptions on pathogenesis of the primary open angle glaucoma / Koshitz, I. N. ; Svetlova, O. V. ; Kotliar, K. E. ; Makarov, F. N. ; Smolnikov, B. A. JF - Glaukoma (2005) Y1 - 2005 N1 - Original in Russisch SP - 41 EP - 63 PB - - ER - TY - JOUR A1 - Horbach, Andreas A1 - Staat, Manfred A1 - Perez-Viana, Daniel A1 - Simmen, Hans-Peter A1 - Neuhaus, Valentin A1 - Pape, Hans-Christoph A1 - Prescher, Andreas A1 - Ciritsis, Bernhard T1 - Biomechanical in vitro examination of a standardized low-volume tubular femoroplasty JF - Clinical Biomechanics N2 - Background Osteoporosis is associated with the risk of fractures near the hip. Age and comorbidities increase the perioperative risk. Due to the ageing population, fracture of the proximal femur also proves to be a socio-economic problem. Preventive surgical measures have hardly been used so far. Methods 10 pairs of human femora from fresh cadavers were divided into control and low-volume femoroplasty groups and subjected to a Hayes fall-loading fracture test. The results of the respective localization and classification of the fracture site, the Singh index determined by computed tomography (CT) examination and the parameters in terms of fracture force, work to fracture and stiffness were evaluated statistically and with the finite element method. In addition, a finite element parametric study with different position angles and variants of the tubular geometry of the femoroplasty was performed. Findings Compared to the control group, the work to fracture could be increased by 33.2%. The fracture force increased by 19.9%. The used technique and instrumentation proved to be standardized and reproducible with an average poly(methyl methacrylate) volume of 10.5 ml. The parametric study showed the best results for the selected angle and geometry. Interpretation The cadaver studies demonstrated the biomechanical efficacy of the low-volume tubular femoroplasty. The numerical calculations confirmed the optimal choice of positioning as well as the inner and outer diameter of the tube in this setting. The standardized minimally invasive technique with the instruments developed for it could be used in further comparative studies to confirm the measured biomechanical results. Y1 - 2020 U6 - http://dx.doi.org/10.1016/j.clinbiomech.2020.105104 VL - 80 IS - Art. 105104 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, I. M. T1 - Biomechanical modeling of the aqueous humor outflow after non-penetrating glaucoma filtration surgery in the human eye JF - Acta of bioengineering and biomechanics Y1 - 2002 SN - 1509-409X VL - Vol. 4 IS - Suppl. 1 SP - 728 EP - 729 ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Svetlova, O. V. A1 - Sourjikov, A. V. A1 - Zaseeva, M. V. T1 - Biomechanical peculiarities of aqueous humor production system and outflow regulation system / Svetlova, O. V. ; Sourjikov, A. V. ; Kotliar, K. E. ; Zaseeva, M. V. ; Shukhaev, S. V. ; Koshitz, I. N. JF - Glaukoma (2004) Y1 - 2004 N1 - Original in Russisch SP - 66 EP - 76 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Svetlova, O. V. A1 - Stegaev, V. A. A1 - Parkhomov, S. D. T1 - Biomechanical substantiation of relatively low efficiency of recurrent laser trabeculoplasty / Svetlova, O. V. ; Stagaev, V. A. ; Parkhomov, S. D. ; Kotliar, K. E. ; Makarov, F. N. ; Smolnikov, B. A. ; Koshitz, I. N. JF - Glaukoma (2004) Y1 - 2004 N1 - Original in Russisch SP - 29 EP - 39 PB - - ER - TY - JOUR A1 - Quittmann, Oliver J. A1 - Abel, Thomas A1 - Albracht, Kirsten A1 - Strüder, Heiko K. T1 - Biomechanics of all-out handcycling exercise: kinetics, kinematics and muscular activity of a 15-s sprint test in able-bodied participants JF - Sports Biomechanics N2 - This study aims to quantify the kinematics, kinetics and muscular activity of all-out handcycling exercise and examine their alterations during the course of a 15-s sprint test. Twelve able-bodied competitive triathletes performed a 15-s all-out sprint test in a recumbent racing handcycle that was attached to an ergometer. During the sprint test, tangential crank kinetics, 3D joint kinematics and muscular activity of 10 muscles of the upper extremity and trunk were examined using a power metre, motion capturing and surface electromyography (sEMG), respectively. Parameters were compared between revolution one (R1), revolution two (R2), the average of revolution 3 to 13 (R3) and the average of the remaining revolutions (R4). Shoulder abduction and internal-rotation increased, whereas maximal shoulder retroversion decreased during the sprint. Except for the wrist angles, angular velocity increased for every joint of the upper extremity. Several muscles demonstrated an increase in muscular activation, an earlier onset of muscular activation in crank cycle and an increased range of activation. During the course of a 15-s all-out sprint test in handcycling, the shoulder muscles and the muscles associated to the push phase demonstrate indications for short-duration fatigue. These findings are helpful to prevent injuries and improve performance in all-out handcycling. KW - Handbike KW - sEMG KW - Paralympic sport KW - performance testing KW - high-intensity exercise Y1 - 2022 U6 - http://dx.doi.org/10.1080/14763141.2020.1745266 SN - 1752-6116 (Onlineausgabe) SN - 1476-3141 (Druckausgabe) VL - 21 IS - 10 SP - 1200 EP - 1223 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Quittmann, Oliver J. A1 - Abel, Thomas A1 - Albracht, Kirsten A1 - Meskemper, Joshua A1 - Foitschik, Tina A1 - Strüder, Heiko K. T1 - Biomechanics of handcycling propulsion in a 30-min continuous load test at lactate threshold: Kinetics, kinematics, and muscular activity in able-bodied participants JF - European Journal of Applied Physiology N2 - Purpose This study aims to investigate the biomechanics of handcycling during a continuous load trial (CLT) to assess the mechanisms underlying fatigue in upper body exercise. Methods Twelve able-bodied triathletes performed a 30-min CLT at a power output corresponding to lactate threshold in a racing recumbent handcycle mounted on a stationary ergometer. During the CLT, ratings of perceived exertion (RPE), tangential crank kinetics, 3D joint kinematics, and muscular activity of ten muscles of the upper extremity and trunk were examined using motion capturing and surface electromyography. Results During the CLT, spontaneously chosen cadence and RPE increased, whereas crank torque decreased. Rotational work was higher during the pull phase. Peripheral RPE was higher compared to central RPE. Joint range of motion decreased for elbow-flexion and radial-duction. Integrated EMG (iEMG) increased in the forearm flexors, forearm extensors, and M. deltoideus (Pars spinalis). An earlier onset of activation was found for M. deltoideus (Pars clavicularis), M. pectoralis major, M. rectus abdominis, M. biceps brachii, and the forearm flexors. Conclusion Fatigue-related alterations seem to apply analogously in handcycling and cycling. The most distal muscles are responsible for force transmission on the cranks and might thus suffer most from neuromuscular fatigue. The findings indicate that peripheral fatigue (at similar lactate values) is higher in handcycling compared to leg cycling, at least for inexperienced participants. An increase in cadence might delay peripheral fatigue by a reduced vascular occlusion. We assume that the gap between peripheral and central fatigue can be reduced by sport-specific endurance training. Y1 - 2020 U6 - http://dx.doi.org/10.1007/s00421-020-04373-x SN - 1439-6327 IS - 120 SP - 1403 EP - 1415 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Grüters, Hugo T1 - Biomechanisch begründete Stimulation postoperativer Knochenumbauvorgänge JF - Biomedizinische Technik . 37 (1992), H. 5 Y1 - 1992 SN - 0013-5585 SP - 94 EP - 98 ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Volkov, V. V. A1 - Koshits, I. N. A1 - Svetlova, O. V. T1 - Biomekhanicheskie osobennosti vzaimodeĭstviia drenazhno i akkomodatsionnoĭ reguliatornykh sistem glaza v norme i pri kontuzionnom podvyvikhe khrustalika / Volkov, V. V. ; Kotliar, K. E. ; Koshits, I. n. ; Svetlova, O. V. ; Smol´nikov, B. A. JF - Vestnik oftalmologii. 113 (1997), H. 3 Y1 - 1997 SN - 0042-465X N1 - Titelübersetzung: Biomechanical characteristics of interactions between the drainage and accommodation regulatory systems of the eye in health and in contusion lens subluxation ; Original in Russisch, English abstract SP - 5 EP - 7 PB - - ER - TY - JOUR A1 - Bork, M. A1 - Kelemen, C. A1 - Biselli, Manfred A1 - Artmann, Gerhard T1 - Biophysikalische Charakterisierung ex vivo kultivierter menschlicher Erythrozythen JF - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1 Y1 - 2000 SN - 1862-278X SP - 471 EP - 472 ER - TY - JOUR A1 - Oliveira, Danilo A. A1 - Molinnus, Denise A1 - Beging, Stefan A1 - Siqueira Jr, José R. A1 - Schöning, Michael Josef T1 - Biosensor Based on Self-Assembled Films of Graphene Oxide and Polyaniline Using a Field-Effect Device Platform JF - physica status solidi (a) applications and materials science N2 - A new functionalization method to modify capacitive electrolyte–insulator–semiconductor (EIS) structures with nanofilms is presented. Layers of polyallylamine hydrochloride (PAH) and graphene oxide (GO) with the compound polyaniline:poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PANI:PAAMPSA) are deposited onto a p-Si/SiO2 chip using the layer-by-layer technique (LbL). Two different enzymes (urease and penicillinase) are separately immobilized on top of a five-bilayer stack of the PAH:GO/PANI:PAAMPSA-modified EIS chip, forming a biosensor for detection of urea and penicillin, respectively. Electrochemical characterization is performed by constant capacitance (ConCap) measurements, and the film morphology is characterized by atomic force microscopy (AFM) and scanning electron microscopy (SEM). An increase in the average sensitivity of the modified biosensors (EIS–nanofilm–enzyme) of around 15% is found in relation to sensors, only carrying the enzyme but without the nanofilm (EIS–enzyme). In this sense, the nanofilm acts as a stable bioreceptor onto the EIS chip improving the output signal in terms of sensitivity and stability. KW - capacitive electrolyte–insulator–semiconductor sensors KW - graphene oxide KW - layer-by-layer technique KW - nanomaterials KW - polyaniline Y1 - 2021 U6 - http://dx.doi.org/10.1002/pssa.202000747 SN - 1862-6319 N1 - Corresponding author: José R. Siqueira Jr & Michael J. Schöning VL - 218 IS - 13 SP - 1 EP - 9 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Keusgen, Michael A1 - Jünger, Martina A1 - Krest, Ingo A1 - Schöning, Michael Josef T1 - Biosensoric detection of the cysteine sulphoxide alliin JF - Sensors and Actuators B. 95 (2003), H. 1-3 Y1 - 2003 SN - 0925-4005 SP - 297 EP - 302 ER - TY - JOUR A1 - Keusgen, M. A1 - Jünger, M. A1 - Schöning, Michael Josef T1 - Biosensoric detection of the cysteine sulphoxide alliin JF - Book of abstracts / ed. by J. Saneistr. Y1 - 2002 SN - 80-01-02576-4 N1 - Eurosensors ; (16, 2002, Praha) SP - 1175 EP - 1178 PB - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement CY - Prague ER - TY - JOUR A1 - Paczkowski, Sebastian A1 - Weißbecker, Bernhard A1 - Schöning, Michael Josef A1 - Schütz, Stefan T1 - Biosensors on the Basis of Insect Olfaction JF - Insect biotechnology / Andreas Vilcinskas, ed. Y1 - 2011 SN - 978-90-481-9640-1 N1 - Biologically-inspired system ; 2 SP - 225 EP - 240 PB - Springer CY - Dordrecht [u.a.] ER -