TY - CHAP A1 - Reisgen, Uwe A1 - Schleser, Markus A1 - Schoene, Jens A1 - Hegger, Josef A1 - Gallwoszus, Jörg A1 - Feldmann, Markus A1 - Kopp, Maik A1 - Gündel, Max ED - Cairns, John W. T1 - Investigation on bond mechanisms of innovative small-scale shear connectors between steel and concrete T2 - Bond in concrete 2012. Vol. 2. Bond in new materials and under severe conditions Y1 - 2012 SN - 978-88-907078-3-4 SP - 893 EP - 898 PB - Publisher creations CY - Manerbio, Brescia ER - TY - CHAP A1 - Schopp, Christoph A1 - Heuermann, Holger A1 - Holtrup, S. T1 - Investigation on efficacy optimization of RF-driven automotive D-lamps T2 - 44th European Microwave Conference (EuMC),2014, Rome Y1 - 2014 U6 - https://doi.org/10.1109/EuMC.2014.6986645 SP - 1154 EP - 1157 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Trzewik, J. A1 - Schmid-Schönbein, G. W. T1 - Investigation on lymphatic endothelial microvalves / Trzewik, J. ; Artmann, G. M. ; Schmid-Schönbein, G. W. JF - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1 Y1 - 2000 SN - 1862-278X SP - 521 EP - 522 ER - TY - JOUR A1 - Helsper, Christoph A1 - Wiedensohler, A. A1 - Lütkemeier, E. A1 - Feldpausch, M. T1 - Investigation on the Bipolar Charge Distribution at Various Gas Conditions / Wiedensohler, A.; Lütkemeier, E.; Feldpausch, M. ; Helsper, C. JF - Journal of Aerosol Science. 17 (1986), H. 3 Y1 - 1986 SN - 0021-8502 SP - 413 EP - 416 ER - TY - CHAP A1 - Weiss, Christian A1 - Heslenfeld, Jonas A1 - Saewe, Jasmin Kathrin A1 - Bremen, Sebastian A1 - Häfner, Constantin Leon T1 - Investigation on the influence of powder humidity in Laser Powder Bed Fusion (LPBF) T2 - Procedia CIRP 12th CIRP Conference on Photonic Technologies [LANE 2022] N2 - In the Laser Powder Bed Fusion (LPBF) process, parts are built out of metal powder material by exposure of a laser beam. During handling operations of the powder material, several influencing factors can affect the properties of the powder material and therefore directly influence the processability during manufacturing. Contamination by moisture due to handling operations is one of the most critical aspects of powder quality. In order to investigate the influences of powder humidity on LPBF processing, four materials (AlSi10Mg, Ti6Al4V, 316L and IN718) are chosen for this study. The powder material is artificially humidified, subsequently characterized, manufactured into cubic samples in a miniaturized process chamber and analyzed for their relative density. The results indicate that the processability and reproducibility of parts made of AlSi10Mg and Ti6Al4V are susceptible to humidity, while IN718 and 316L are barely influenced. KW - LPBF KW - Additive Manufacturing KW - Powder Material KW - Humidity Y1 - 2022 U6 - https://doi.org/10.1016/j.procir.2022.08.102 SN - 2212-8271 N1 - 12th CIRP Conference on Photonic Technologies [LANE 2022], 04. September 2022 bis 08. September 2022, Fürth VL - 111 SP - 115 EP - 120 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Zhubanova, A. A. T1 - Investigation the Influence of Carbonized Material Based On Rice Husk on Viability and Migration of Fibroblasts in T3B3 Cell Culture JF - KazNU Bulletin. Biology series Y1 - 2013 SN - 1563-0218 N1 - Original in russischer Sprache VL - 59 IS - 3/1 SP - 20 EP - 23 ER - TY - JOUR A1 - Feuerriegel, Uwe A1 - Klose, W. T1 - Investigations into the Mechanism of the Deactivation of a Palladium-Supported Catalyst by Hydrogen Sulfide Poisoning. Klose, W. ; Feuerriegel, U. JF - Chemical engineering & technology. 21 (1998), H. 7 Y1 - 1998 SN - 0930-7516 N1 - gleicher Artikel in Deutsch In: Chem.Ing.Tech 70(1998) No S. 449-452 u.d.T.: Untersuchungen zum Mechanismus der Desaktivierung eines Palladium-Trägerkatalysators durch Vergiftung mit Schwefelwasserstoff SP - 562 EP - 564 ER - TY - JOUR A1 - Krause, Gregor A1 - Neubert, R. A1 - Pietsch, R. T1 - Investigations of Electrical Aging in Polymers under High AC-Field Strength JF - 1990 annual report : October 28 - October 31, 1990 / sponsored by the IEEE Dielectrics and Electrical Insulation Society Y1 - 1990 N1 - Conference on Electrical Insulation and Dielectric Phenomena ; (59, 1990, Pocono Manor, Pa.) PB - IEEE Service Center CY - Piscataway, N.J ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Haenni, D. R. T1 - Investigations of high spin states in ¹³⁸,¹³⁹ Nd JF - Annual report 1978 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 36) Y1 - 1979 SP - 24 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Savitkaya, I.S. A1 - Zhubanova, A.A. A1 - Tastambek, K.T. T1 - Investigations of LPS endotoxin elimination in the flowing column conditions with the sorbent on the basis of carbonized rice husk JF - KazNU Bulletin. Biology series Y1 - 2013 SN - 1563-0218 N1 - Original in russischer Sprache VL - 57 IS - 1 SP - 124 EP - 127 ER - TY - JOUR A1 - Anik, Sabri A1 - Frohberg, Martin G. T1 - Investigations of the thermodynamics of oxygen and the determination of the miscibility gap in the system copper-oxygen-lead at 12000C JF - Zeitschrift für Metallkunde Y1 - 1984 SN - 0044-3093 VL - 75 IS - 8 SP - 586 EP - 589 ER - TY - CHAP A1 - Heinz, G. A1 - Oertel, Mario A1 - Bung, Daniel Bernhard ED - Janssen, Robert T1 - Investigations on a cooling water system for a gas tubine facility concerning air vortexes and sediment transport T2 - Hydraulic structures: useful water harvesting systems or relics? : Third International Junior Researcher and Engineer Workshop on Hydraulic Structures (IJREWHS'10) : Edinburgh, Scotland, U.K., 2-3 May 2010 Y1 - 2010 SN - 9781742720159 SP - 109 EP - 116 PB - School of Civil Engineering, The University of Queensland CY - Brisbane ER - TY - JOUR A1 - Helsper, Christoph A1 - Mölter, W. A1 - Löffler, F. A1 - Wadenpohl, C. T1 - Investigations on a New Aerosol Generator for the Production of Carbon Aggregate Particles / Helsper, C. ; Mölter, W. ; Löffler, F. ; Wadenpohl, C. ; Kaufmann, S. ; Wenninger, G. JF - Atmospheric Environment. Part A. General Topics. 27 A (1993), H. 8 Y1 - 1993 SN - 1352-2310 SP - 1271 EP - 1275 ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Crott, M. A1 - Ronkel, F. A1 - Thust, M. A1 - Schultze, J. W. A1 - Kordos, P. A1 - Lüth, H. T1 - Investigations on porous silicon layers with regard to chemical microsensor applications JF - Third International Conference on Intelligent Materials : Lyon, 3-4-5 June 1996, Center of Congress "L'Espace Tête d'Or" / [publ. by SPIE, the International Society for Optical Engineering]. General chair/ed. by: P. F. Gobin Y1 - 1996 SN - 0819421650 N1 - International Conference on Intelligent Materials ; (3, 1996, Lyon) SP - 275 EP - 280 PB - SPIE CY - Bellingham, Wash. ER - TY - CHAP A1 - Sauerborn, Markus T1 - Investigations to the influence of clouds and aerosols to the haze of the sunshape T2 - SolarPACES 2011 : concentrating solar power and chemical energy systems : 20 - 23 September, 2011, Granada, Spain Y1 - 2011 CY - Granada ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Bruns, M. A1 - Hoffmann, W. A1 - Hoffmann, B. (u.a.) T1 - Iodide ion-sensitive field-effect structures JF - Sensors and Actuators B. 15 (1993), H. 1-3 Y1 - 1993 SN - 0925-4005 SP - 192 EP - 194 ER - TY - JOUR A1 - Weckesser, Martin A1 - Grießmeier, Martin A1 - Schmidt, Daniela A1 - Sonnenberg, Frank A1 - Ziemons, Karl A1 - Kemna, Lars A1 - Holschbach, Marcus A1 - Langen, Karl-J. A1 - Müller-Gärtner, Hans-W. T1 - Iodine-123 α-methyl tyrosine single-photon emission tomography of cerebral gliomas: standardised evaluation of tumour uptake and extent JF - European Journal of Nuclear Medicine N2 - Single-photon emission tomography (SPET) with the amino acid analogue l-3-[123I]iodo-α-methyl tyrosine (IMT) is helpful in the diagnosis and monitoring of cerebral gliomas. Radiolabelled amino acids seem to reflect tumour infiltration more specifically than conventional methods like magnetic resonance imaging and computed tomography. Automatic tumour delineation based on maximal tumour uptake may cause an overestimation of mean tumour uptake and an underestimation of tumour extension in tumours with circumscribed peaks. The aim of this study was to develop a program for tumour delineation and calculation of mean tumour uptake which takes into account the mean background activity and is thus optimised to the problem of tumour definition in IMT SPET. Using the frequency distribution of pixel intensities of the tomograms a program was developed which automatically detects a reference brain region and draws an isocontour region around the tumour taking into account mean brain radioactivity. Tumour area and tumour/brain ratios were calculated. A three-compartment phantom was simulated to test the program. The program was applied to IMT SPET studies of 20 patients with cerebral gliomas and was compared to the results of manual analysis by three different investigators. Activity ratios and chamber extension of the phantom were correctly calculated by the automatic analysis. A method based on image maxima alone failed to determine chamber extension correctly. Manual region of interest analysis in patient studies resulted in a mean inter-observer standard deviation of 8.7%±6.1% (range 2.7%–25.0%). The mean value of the results of the manual analysis showed a significant correlation to the results of the automatic analysis (r = 0.91, P<0.0001 for the uptake ratio; r = 0.87, P<0.0001 for the tumour area). We conclude that the algorithm proposed simplifies the calculation of uptake ratios and may be used for observer-independent evaluation of IMT SPET studies. Three-dimensional tumour recognition and transfer to co-registered morphological images based on this program may be useful for the planning of surgical and radiation treatment. Y1 - 1998 SN - 1619-7089 VL - 25 IS - 2 SP - 150 EP - 156 ER - TY - JOUR A1 - Mourzina, Y. G. A1 - Yoshinobu, T. A1 - Schubert, J. A1 - Lüth, H. A1 - Iwasaki, H. A1 - Schöning, Michael Josef T1 - Ion-selective lightaddressable potentiometric sensor (LAPS) with chalcogenide thin film by pulsed laser deposition JF - Sensors and Actuators B. 80 (2001), H. 2 Y1 - 2001 SN - 0925-4005 SP - 136 EP - 140 ER - TY - CHAP A1 - Beging, Stefan A1 - Poghossian, Arshak A1 - Mlynek, D. A1 - Hataihimakul, S. A1 - Pedraza, A. A1 - Dhawan, S. A1 - Laube, N. A1 - Kleinen, L. A1 - Baldsiefen, G. A1 - Busch, H. A1 - Schöning, Michael Josef T1 - Ion-selective sensors for the determination of the risk of urinary stone formation T2 - Micro- and Nanosystems in biochemical diagnosis : Principles and applications Y1 - 2010 SP - 74 EP - 80 CY - Warsaw ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Sauke, M. A1 - Steffen, A. A1 - Marso, M. (u.a.) T1 - Ion-sensitive field-effect transistors with ultrathin Langmuir-Blodgett membranes JF - Sensors and Actuators B. 27 (1995), H. 1-3 Y1 - 1995 SN - 0925-4005 SP - 325 EP - 328 ER - TY - JOUR A1 - Alhwarin, Faraj A1 - Ferrein, Alexander A1 - Scholl, Ingrid T1 - IR stereo kinect: improving depth images by combining structured light with IR stereo Y1 - 2014 SP - 1 EP - 9 ER - TY - CHAP A1 - Alhwarin, Faraj A1 - Ferrein, Alexander A1 - Scholl, Ingrid T1 - IR stereo kinect: improving depth images by combining structured light with IR stereo T2 - PRICAI 2014: Trends in artificial intelligence : 13th Pacific Rim International Conference on Artificial Intelligence : Gold Coast, QLD, Australia, December 1-5, 2014 : proceedings. (Lecture notes in computer science ; vol. 8862) N2 - RGB-D sensors such as the Microsoft Kinect or the Asus Xtion are inexpensive 3D sensors. A depth image is computed by calculating the distortion of a known infrared light (IR) pattern which is projected into the scene. While these sensors are great devices they have some limitations. The distance they can measure is limited and they suffer from reflection problems on transparent, shiny, or very matte and absorbing objects. If more than one RGB-D camera is used the IR patterns interfere with each other. This results in a massive loss of depth information. In this paper, we present a simple and powerful method to overcome these problems. We propose a stereo RGB-D camera system which uses the pros of RGB-D cameras and combine them with the pros of stereo camera systems. The idea is to utilize the IR images of each two sensors as a stereo pair to generate a depth map. The IR patterns emitted by IR projectors are exploited here to enhance the dense stereo matching even if the observed objects or surfaces are texture-less or transparent. The resulting disparity map is then fused with the depth map offered by the RGB-D sensor to fill the regions and the holes that appear because of interference, or due to transparent or reflective objects. Our results show that the density of depth information is increased especially for transparent, shiny or matte objects. Y1 - 2014 SN - 978-3-319-13559-5 (Print) ; 978-3-319-13560-1 (E-Book) U6 - https://doi.org/10.1007/978-3-319-13560-1_33 SP - 409 EP - 421 PB - Springer CY - München ER - TY - JOUR A1 - Leschinger, Tim A1 - Besch, Katharina A1 - Aydin, Cansu A1 - Staat, Manfred A1 - Scaal, Martin A1 - Müller, Lars Peter A1 - Wegmann, Kilian T1 - Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique JF - The Orthopaedic Journal of Sports Medicine Y1 - 2019 U6 - https://doi.org/10.1177/2325967119864590 VL - 7 IS - 8 SP - 1 EP - 5 ER - TY - CHAP A1 - Diekmann, Julian A1 - Eggert, Mathias T1 - Is a Progressive Web App an Alternative for Native App Development? T2 - 3. Wissenschaftsforum: Digitale Transformation (WiFo21) (Lecture Notes in Informatics ; P-319) N2 - The existence of several mobile operating systems, such as Android and iOS, is a challenge for developers because the individual platforms are not compatible with each other and require separate app developments. For this reason, cross-platform approaches have become popular but lack in cloning the native behavior of the different operating systems. Out of the plenty cross-platform approaches, the progressive web app (PWA) approach is perceived as promising but needs further investigation. Therefore, the paper at hand aims at investigating whether PWAs are a suitable alternative for native apps by developing a PWA clone of an existing app. Two surveys are conducted in which potential users test and evaluate the PWA prototype with regard to its usability. The survey results indicate that PWAs have great potential, but cannot be treated as a general alternative to native apps. For guiding developers when and how to use PWAs, four design guidelines for the development of PWA-based apps are derived based on the results. KW - Progressive Web App KW - PWA KW - Cross-platform KW - Evaluation KW - Mobile web Y1 - 2021 SN - 978-3-88579-713-5 SP - 35 EP - 48 PB - Gesellschaft für Informatik CY - Darmstadt ER - TY - CHAP A1 - Brockmann, Carsten A1 - Sultanow, Eldar A1 - Czarnecki, Christian ED - Draude, Claude ED - Lange, Martin ED - Sick, Bernhard T1 - Is enterprise architecture still relevant in the digital age? T2 - GI Edition Proceedings Band 295 INFORMATIK 2019, Workshop-Beiträge KW - Preface KW - Enterprise Architecture KW - Digital Age Y1 - 2019 SN - 9783885796893 U6 - https://doi.org/10.18420/inf2019_ws01 SN - 1617-5468 N1 - 50 Jahre Gesellschaft für Informatik – Informatik für Gesellschaft. 16. September, Kassel SP - 21 EP - 21 PB - Köllen CY - Bonn ER - TY - JOUR A1 - Egli, Simon A1 - Ayer, François A1 - Peter, Martina A1 - Eilmann, Britta A1 - Rigling, Andreas T1 - Is forest mushroom productivity driven by tree growth? Results from a thinning experiment JF - Annals of Forest Science N2 - • Most of the edible forest mushrooms are mycorrhizal and depend on carbohydrates produced by the associated trees. Fruiting patterns of these fungi are not yet fully understood since climatic factors alone do not completely explain mushroom occurrence. • The objective of this study was to retrospectively find out if changing tree growth following an increment thinning has influenced the diversity patterns and productivity of associated forest mushrooms in the fungus reserve La Chanéaz, Switzerland. • The results reveal a clear temporal relationship between the thinning, the growth reaction of trees and the reaction of the fungal community, especially for the ectomycorrhizal species. The tree-ring width of the formerly suppressed beech trees and the fruit body number increased after thinning, leading to a significantly positive correlation between fruit body numbers and tree-ring width. • Fruit body production was influenced by previous annual tree growth, the best accordance was found between fruit body production and the tree-ring width two years previously. • The results support the hypothesis that ectomycorrhizal fruit body production must be linked with the growth of the associated host trees. Moreover, the findings indicate the importance of including mycorrhizal fungi as important players when discussing a tree as a carbon source or sink. Y1 - 2010 U6 - https://doi.org/10.1051/forest/2010011 SN - 1286-4560 (Print) SN - 1297-966X (Online) VL - 67 IS - 5 SP - 509 PB - Springer CY - Paris ER - TY - JOUR A1 - Burmistrova, Natalia A. A1 - Soboleva, Polina M. A1 - Monakhova, Yulia T1 - Is infrared spectroscopy combined with multivariate analysis a promising tool for heparin authentication? JF - Journal of Pharmaceutical and Biomedical Analysis N2 - The investigation of the possibility to determine various characteristics of powder heparin (n = 115) was carried out with infrared spectroscopy. The evaluation of heparin samples included several parameters such as purity grade, distributing company, animal source as well as heparin species (i.e. Na-heparin, Ca-heparin, and heparinoids). Multivariate analysis using principal component analysis (PCA), soft independent modelling of class analogy (SIMCA), and partial least squares – discriminant analysis (PLS-DA) were applied for the modelling of spectral data. Different pre-processing methods were applied to IR spectral data; multiplicative scatter correction (MSC) was chosen as the most relevant. Obtained results were confirmed by nuclear magnetic resonance (NMR) spectroscopy. Good predictive ability of this approach demonstrates the potential of IR spectroscopy and chemometrics for screening of heparin quality. This approach, however, is designed as a screening tool and is not considered as a replacement for either of the methods required by USP and FDA. KW - IR spectroscopy KW - Heparin KW - Authenticity KW - Principal component analysis KW - Soft independent modeling of class analogy Y1 - 2021 SN - 0731-7085 U6 - https://doi.org/10.1016/j.jpba.2020.113811 VL - 194 IS - Article number: 113811 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Burger, René A1 - Rumpf, Jessica A1 - Do, Xuan Tung A1 - Monakhova, Yulia A1 - Diehl, Bernd W. K. A1 - Rehahn, Matthias A1 - Schulze, Margit T1 - Is NMR combined with multivariate regression applicable for the molecular weight determination of randomly cross-linked polymers such as lignin? JF - ACS Omega N2 - The molecular weight properties of lignins are one of the key elements that need to be analyzed for a successful industrial application of these promising biopolymers. In this study, the use of 1H NMR as well as diffusion-ordered spectroscopy (DOSY NMR), combined with multivariate regression methods, was investigated for the determination of the molecular weight (Mw and Mn) and the polydispersity of organosolv lignins (n = 53, Miscanthus x giganteus, Paulownia tomentosa, and Silphium perfoliatum). The suitability of the models was demonstrated by cross validation (CV) as well as by an independent validation set of samples from different biomass origins (beech wood and wheat straw). CV errors of ca. 7–9 and 14–16% were achieved for all parameters with the models from the 1H NMR spectra and the DOSY NMR data, respectively. The prediction errors for the validation samples were in a similar range for the partial least squares model from the 1H NMR data and for a multiple linear regression using the DOSY NMR data. The results indicate the usefulness of NMR measurements combined with multivariate regression methods as a potential alternative to more time-consuming methods such as gel permeation chromatography. Y1 - 2021 U6 - https://doi.org/10.1021/acsomega.1c03574 SN - 2470-1343 VL - 6 IS - 44 SP - 29516 EP - 29524 PB - ACS Publications CY - Washington, DC ER - TY - JOUR A1 - Lindner, Simon A1 - Burger, René A1 - Rutledge, Douglas N. A1 - Do, Xuan Tung A1 - Rumpf, Jessica A1 - Diehl, Bernd W. K. A1 - Schulze, Margit A1 - Monakhova, Yulia T1 - Is the calibration transfer of multivariate calibration models between high- and low-field NMR instruments possible? A case study of lignin molecular weight JF - Analytical chemistry N2 - Although several successful applications of benchtop nuclear magnetic resonance (NMR) spectroscopy in quantitative mixture analysis exist, the possibility of calibration transfer remains mostly unexplored, especially between high- and low-field NMR. This study investigates for the first time the calibration transfer of partial least squares regressions [weight average molecular weight (Mw) of lignin] between high-field (600 MHz) NMR and benchtop NMR devices (43 and 60 MHz). For the transfer, piecewise direct standardization, calibration transfer based on canonical correlation analysis, and transfer via the extreme learning machine auto-encoder method are employed. Despite the immense resolution difference between high-field and low-field NMR instruments, the results demonstrate that the calibration transfer from high- to low-field is feasible in the case of a physical property, namely, the molecular weight, achieving validation errors close to the original calibration (down to only 1.2 times higher root mean square errors). These results introduce new perspectives for applications of benchtop NMR, in which existing calibrations from expensive high-field instruments can be transferred to cheaper benchtop instruments to economize. Y1 - 2022 SN - 1520-6882 U6 - https://doi.org/10.1021/acs.analchem.1c05125 VL - 94 IS - 9 SP - 3997 EP - 4004 PB - ACS Publications CY - Washington, DC ER - TY - JOUR A1 - Havermann, Marc A1 - Moeglin, J.-P. T1 - ISL's Research on Systems with Controlled Effects for Non-Lethal Applications / Moeglin, J.-P. ; Havermann, M. et al. JF - Non-lethal options enhancing security and stability : 3rd European Symposium on Non-Lethal Weapons, May 10 - 12, 2005, Ettlingen, Germany / ICT, Fraunhofer-Institut Chemische Technologie; European Working Group Non-Lethal Weapons Y1 - 2005 N1 - European Symposium on Non-Lethal Weapons ; (3 ; 2005.5.10-12 ; Ettlingen); P 35 PB - ICT CY - Pfinztal ER - TY - JOUR A1 - Kalbe, Jochen A1 - Kuropka, Rolf A1 - Meyer-Stork, L. Sebastian A1 - Berndt, Heinz A1 - Sauter, Sybille L. A1 - Loss, Peter A1 - Hendo, Karsten A1 - Riesner, Detlev A1 - Höcker, Hartwig T1 - Isolation and characterization of high-molecular mass DNA from hair shafts JF - Biological chemistry Y1 - 1988 SN - 0177-3593 U6 - https://doi.org/10.1515/bchm3.1988.369.1.413 VL - 369 IS - 1 SP - 413 EP - 416 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Beuscher, H. A1 - Gono, Y. T1 - Isomeric 10⁺ states in nuclei with N=78 JF - Proceedings of the International Conference on Nuclear Structure : Tokyo, Sept. 5 - 10, 1977 / ed. by T. Marumori. - Journal of the Physical Society of Japan ; Vol. 44, 1978 : Suppl. Y1 - 1978 N1 - International Conference on Nuclear Structure <1977, Tokyo> SP - 861 PB - Physical Soc. of Japan CY - Tokyo ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Bochev, B. A1 - Kutsarova, T. T1 - Isomeric state in ¹³⁴ La JF - Annual report 1980 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: F. Grümmer. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 99) Y1 - 1981 SP - 47 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Bochev, B. A1 - Kutsarova, T. T1 - Isomeric state in ¹³⁶ La JF - Annual report 1980 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: F. Grümmer. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 99) Y1 - 1981 SP - 48 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Beuscher, H. A1 - Bochev, B. T1 - Isomeric states in ¹³⁴ Ba JF - Zeitschrift für Physik / A, Hadrons and nuclei. 298 (1980), H. 4 Y1 - 1980 SN - 1431-5831 SP - 267 EP - 271 ER - TY - JOUR A1 - Müller-Veggian, Mattea A1 - Morek, T. A1 - Beuscher, H. A1 - Bochev, B. T1 - Isomeric states in ¹³⁴ Ba JF - Annual report 1979 / Kernforschungsanlage Jülich Institut für Kernphysik / Hrsg.: A. Fässler. - (Spezielle Berichte der Kernforschungsanlage Jülich ; 72) Y1 - 1980 SP - 44 PB - Kernforschungsanlage CY - Jülich ER - TY - JOUR A1 - Pietsch, Wolfram T1 - IT Service Deployment JF - QFD : transactions from International Symposium on QFD 2007 - Williamsburg, the Nineteenth Symposium on Quality Function Deployment ; September 7 - 8, 2007, Williamsburg, VA ; [companion document to the Thirteenth International and Nineteenth North American Symposium on Quality Function Deployment (ISQFD'07)] / [organized and hosted by the QFD Institute] Y1 - 2007 SN - 1-889477-19-2 N1 - QFD 2007, 19th Symposium on Quality Function Deployment, Williamsburg, VA, US, Sep 7-8, 2007 SP - 203 EP - 212 PB - QFD Inst. CY - Ann Arbor, Mich. ER - TY - JOUR A1 - Ziemons, Karl A1 - Herzog, H. A1 - Feinendegen, L. E. T1 - Iterative image reconstruction with weighted pixel contribution to projection element JF - European Journal of Nuclear Medicine Y1 - 1990 SN - 1619-7089 N1 - Abstracts of the European Association of Nuclear Medicine Congress ; V52 VL - 16 IS - 7 SP - 403 EP - 403 ER - TY - JOUR A1 - Ziemons, Karl A1 - Herzog, H. A1 - Bosetti, P. A1 - Feinendegen, L. E. T1 - Iterative image reconstruction with weighted pixel contribution to projection elements JF - European Journal of Nuclear Medicine Y1 - 1992 SN - 1619-7089 N1 - Abstracts of the European Association of Nuclear Medicine Congress 23–26 August 1992 Lisboa, Portugal ; V143-2 VL - 19 IS - 8 SP - 588 EP - 588 ER - TY - CHAP A1 - Ketelhut, Maike A1 - Göll, Fabian A1 - Braunstein, Bjoern A1 - Albracht, Kirsten A1 - Abel, Dirk T1 - Iterative learning control of an industrial robot for neuromuscular training T2 - 2019 IEEE Conference on Control Technology and Applications N2 - Effective training requires high muscle forces potentially leading to training-induced injuries. Thus, continuous monitoring and controlling of the loadings applied to the musculoskeletal system along the motion trajectory is required. In this paper, a norm-optimal iterative learning control algorithm for the robot-assisted training is developed. The algorithm aims at minimizing the external knee joint moment, which is commonly used to quantify the loading of the medial compartment. To estimate the external knee joint moment, a musculoskeletal lower extremity model is implemented in OpenSim and coupled with a model of an industrial robot and a force plate mounted at its end-effector. The algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee. The results show that the algorithm is able to minimize the external knee joint moment in all three cases and converges after less than seven iterations. KW - Knee KW - Training KW - Load modeling KW - Force KW - Iterative learning control Y1 - 2019 SN - 978-1-7281-2767-5 (ePub) SN - 978-1-7281-2766-8 (USB) SN - 978-1-7281-2768-2 (PoD) U6 - https://doi.org/10.1109/CCTA.2019.8920659 N1 - 2019 IEEE Conference on Control Technology and Applications (CCTA) Hong Kong, China, August 19-21, 2019 PB - IEEE CY - New York ER - TY - JOUR A1 - Moosdorf, Andreas T1 - It’s not just the Talent, it’s the Knowledge Transfer Method JF - GC Ticker Y1 - 2009 IS - 1 SP - 16 EP - 16 ER - TY - JOUR A1 - Ziemons, Karl T1 - Jet production and fragmentation properties in deep inelastic muon scattering JF - Zeitschrift für Physik C : Particles and Fields Y1 - 1987 SN - 0170-9739 N1 - European Muon Collaboration VL - 36 IS - 4 SP - 527 EP - 543 ER - TY - JOUR A1 - Berghoff, G. A1 - Lanske, D. A1 - Schultze, K. A1 - Ziemons, Karl T1 - Jets and QCD-effects in muon-nuclean scattering JF - Verhandlungen der Deutschen Physikalischen Gesellschaft Y1 - 1988 SN - 0420-0195 VL - 23 IS - 5 ER - TY - CHAP A1 - Fateri, Miranda A1 - Gebhardt, Andreas T1 - Jewelry fabrication via selective laser melting of glass T2 - ASME 2014 12th Biennial Conference on Engineering Systems Design and Analysis Volume 1: Applied Mechanics; Automotive Systems; Biomedical Biotechnology Engineering; Computational Mechanics; Design; Digital Manufacturing; Education; Marine and Aerospace Applications N2 - Selective Laser Melting (SLM) is one of the Additive Manufacturing (AM) technologies applicable for producing complex geometries which are typically expensive or difficult to fabricate using conventional methods. This process has been extensively investigated experimentally for various metals and the fabrication process parameters have been established for different applications; however, fabricating 3D glass objects using SLM technology has remained a challenge so far although it could have many applications. This paper presents a summery on various experimental evaluations of a material database incorporating the build parameters of glass powder using the SLM process for jewelry applications. Y1 - 2014 SN - 978-0-7918-4583-7 U6 - https://doi.org/10.1115/ESDA2014-20380 SP - V001T06A005 ER - TY - JOUR A1 - Gligorevic, Snjezana T1 - Joint channel estimation and equalisation of fast time-varying frequency-selective channels JF - European transactions on telecommunications Y1 - 2008 SN - 1541-8251; 2161-3915; 1120-3862; 1124-318X VL - Vol. 19 IS - Iss. 1 SP - 1 EP - 13 ER - TY - CHAP A1 - Gligorevic, Snjezana T1 - Joint channel estimation and equalization for fast time-variant multipath channels T2 - Proceedings / 13th IEEE International Symposium on Personal, Indoor and Mobile Radio Communications : PIMRC 2002 : Lisboa, Portugal, September 15 - 18, 2002 Y1 - 2002 SN - 0-7803-7589-0 SP - 1127 EP - 1130 ER - TY - CHAP A1 - Hadinejad-Mahram, Hafez A1 - Gligorevic, Snjezana A1 - Ritscher, Matthias T1 - Joint iterative channel estimation and parallel interference cancellation for coded DS-CDMA T2 - Proceeding of the International Conference on Telecommunications 2002 : [Beijing, 23 - 26 June 2002]. Vol. 2 Y1 - 2002 SP - 566 EP - 570 ER - TY - CHAP A1 - Braunstein, Bjoern A1 - Goldmann, Jan-Peter A1 - Albracht, Kirsten A1 - Sanno, Maximilian A1 - Willwacher, Steffen A1 - Heinrich, Kai A1 - Herrmann, Volker A1 - Brüggemann, Gert-Peter T1 - Joint specific contribution of mechanical power and work during acceleration and top speed in elite sprinters T2 - 31 International Conference on Biomechanics in Sports, Taipei, Taiwan, July 07 - July 22, 2013 Y1 - 2013 SN - 1999-4168 ER - TY - CHAP A1 - Goldmann, Jan-Peter A1 - Braunstein, Bjoern A1 - Heinrich, Kai A1 - Sanno, Maximilian A1 - Stäudle, Benjamin A1 - Ritzdorf, Wolfgang A1 - Brüggemann, Gert-Peter A1 - Albracht, Kirsten T1 - Joint work of the take-off leg during elite high jump T2 - Proceedings of the 33th International Conference on Biomechanics in Sports (ISBS) Y1 - 2015 ER - TY - BOOK A1 - Thielemann, Frank A1 - Staudt, Erich A1 - Kriegesmann, Bernd T1 - Joint-ventures. Staudt, Erich; Kriegesmann, Bernd; Thielemann, Frank Y1 - 1994 N1 - Berichte aus der angewandten Innovationsforschung ; 133 PB - Inst. für Angewandte Innovationsforschung e.V. CY - Bochum ER - TY - CHAP A1 - Uibel, Thomas A1 - Blaß, Hans-Joachim T1 - Joints with Dowel Type Fasteners in CLT structures T2 - Focus solid timber solutions : European Conference on Cross Laminated Timber (CLT); May 21-22, 2013, Graz University of Technology, Austria Y1 - 2013 SN - 978-1-85790-181-8 ; 1-85790-181-9 SP - 119 EP - 134 ER - TY - JOUR A1 - Kempt, Hendrik A1 - Freyer, Nils A1 - Nagel, Saskia K. T1 - Justice and the normative standards of explainability in healthcare JF - Philosophy & Technology N2 - Providing healthcare services frequently involves cognitively demanding tasks, including diagnoses and analyses as well as complex decisions about treatments and therapy. From a global perspective, ethically significant inequalities exist between regions where the expert knowledge required for these tasks is scarce or abundant. One possible strategy to diminish such inequalities and increase healthcare opportunities in expert-scarce settings is to provide healthcare solutions involving digital technologies that do not necessarily require the presence of a human expert, e.g., in the form of artificial intelligent decision-support systems (AI-DSS). Such algorithmic decision-making, however, is mostly developed in resource- and expert-abundant settings to support healthcare experts in their work. As a practical consequence, the normative standards and requirements for such algorithmic decision-making in healthcare require the technology to be at least as explainable as the decisions made by the experts themselves. The goal of providing healthcare in settings where resources and expertise are scarce might come with a normative pull to lower the normative standards of using digital technologies in order to provide at least some healthcare in the first place. We scrutinize this tendency to lower standards in particular settings from a normative perspective, distinguish between different types of absolute and relative, local and global standards of explainability, and conclude by defending an ambitious and practicable standard of local relative explainability. KW - Clinical decision support systems KW - Justice KW - Medical AI KW - Explainability KW - Normative standards Y1 - 2022 U6 - https://doi.org/10.1007/s13347-022-00598-0 VL - 35 IS - Article number: 100 SP - 1 EP - 19 PB - Springer Nature CY - Berlin ER - TY - JOUR A1 - Mourzina, Y. A1 - Mai, T. A1 - Poghossian, Arshak A1 - Ermolenko, Y. A1 - Yoshinobu, T. A1 - Vlasov, Y. A1 - Iwasaki, H. A1 - Schöning, Michael Josef T1 - K+-selective field-effect sensors as transducers for bioelectronic applications JF - Electrochimica Acta. 48 (2003), H. 20-22 Y1 - 2003 SN - 0013-4686 SP - 3333 EP - 3339 ER - TY - JOUR A1 - Hillen, Walter T1 - K0 production in e+e− annihilations at 30 GeV center of mass energy. TASSO Collaboration JF - Physics Letters B. 94 (1980), H. 1 Y1 - 1980 SN - 0370-2693 SP - 91 EP - 95 ER - TY - BOOK A1 - Wolf, Martin R. A1 - Foltz, Christian A1 - Killich, S. T1 - K3 User Guide Y1 - 2000 SP - 1 EP - 13 PB - RWTH CY - Aachen ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Simsek, Beril A1 - Shalaby, Ahmed A1 - Krause, Hans-Joachim T1 - Key contributors to signal generation in frequency mixing magnetic detection (FMMD): an in silico study JF - Sensors N2 - Frequency mixing magnetic detection (FMMD) is a sensitive and selective technique to detect magnetic nanoparticles (MNPs) serving as probes for binding biological targets. Its principle relies on the nonlinear magnetic relaxation dynamics of a particle ensemble interacting with a dual frequency external magnetic field. In order to increase its sensitivity, lower its limit of detection and overall improve its applicability in biosensing, matching combinations of external field parameters and internal particle properties are being sought to advance FMMD. In this study, we systematically probe the aforementioned interaction with coupled Néel–Brownian dynamic relaxation simulations to examine how key MNP properties as well as applied field parameters affect the frequency mixing signal generation. It is found that the core size of MNPs dominates their nonlinear magnetic response, with the strongest contributions from the largest particles. The drive field amplitude dominates the shape of the field-dependent response, whereas effective anisotropy and hydrodynamic size of the particles only weakly influence the signal generation in FMMD. For tailoring the MNP properties and parameters of the setup towards optimal FMMD signal generation, our findings suggest choosing large particles of core sizes dc > 25 nm nm with narrow size distributions (σ < 0.1) to minimize the required drive field amplitude. This allows potential improvements of FMMD as a stand-alone application, as well as advances in magnetic particle imaging, hyperthermia and magnetic immunoassays. KW - key performance indicators KW - magnetic biosensing KW - coupled Néel–Brownian relaxation dynamics KW - frequency mixing magnetic detection KW - magnetic relaxation KW - micromagnetic simulation KW - magnetic nanoparticles Y1 - 2024 U6 - https://doi.org/10.3390/s24061945 SN - 1424-8220 N1 - This article belongs to the Special Issue "Advances in Magnetic Sensors and Their Applications" VL - 24 IS - 6 PB - MDPI CY - Basel ER - TY - BOOK A1 - Laack, Walter van T1 - Key to Eternity / Walter van Laack. [Transl. by Anneliese Wolstenholme] Y1 - 2000 SN - 978-3-8311-0344-7 N1 - Schlüssel zur Ewigkeit PB - van Laack CY - Aachen ER - TY - CHAP A1 - Abel, Thomas A1 - Bonin, Dominik A1 - Albracht, Kirsten A1 - Zeller, Sebastian A1 - Brüggemann, Gert-Peter A1 - Burkett, Brendan A1 - Strüder, Heiko K. T1 - Kinematic profile of the elite handcyclist T2 - 28th International Conference on Biomechanics in Sports, Marquette, Michigan, USA, July 19 – 23, 2010 Y1 - 2017 SN - 1999-4168 SP - 140 EP - 141 ER - TY - CHAP A1 - Scheer, Nico A1 - Chu, Xiaoyan A1 - Salphati, Laurent A1 - Zamek-Gliszczynski, Maciej J. ED - Nicholls, Glynis T1 - Knockout and humanized animal models to study membrane transporters in drug development T2 - Drug Transporters: Volume 1: Role and Importance in ADME and Drug Development Y1 - 2016 SN - 978-1-78262-379-3 U6 - https://doi.org/10.1039/9781782623793-00298 SP - 298 EP - 332 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Pietschmann, Bernd P. A1 - Ruhtz, Vanessa T1 - Knowledge Management JF - Personal : Zeitschrift für Human Resource Management. 53 (2001), H. 5 Y1 - 2001 SN - 0031-5605 SP - 242 EP - 249 ER - TY - BOOK A1 - Janz, Norbert A1 - Goedhuys, Micheline A1 - Mohnen, Pierre T1 - Knowledge-based productivity in "low-tech" industries : evidence from firms in developing countries / Goedhuys, Micheline ; Janz, Norbert ; Mohnen, Pierre Y1 - 2008 N1 - Working paper series // United Nations University, UNU-MERIT ; 2008,007 PB - UNU-MERIT CY - Maastricht ER - TY - JOUR A1 - Goedhuys, Micheline A1 - Janz, Norbert A1 - Mohnen, Pierre T1 - Knowledge-based productivity in “low-tech” industries: evidence from firms in developing countries JF - Industrial and corporate change N2 - Using firm-level data from five developing countries—Brazil, Ecuador, South Africa, Tanzania, and Bangladesh—and three industries—food processing, textiles, and the garments and leather products—this article examines the importance of various sources of knowledge for explaining productivity and formally tests whether sector- or country-specific characteristics dominate these relationships. Knowledge sources driving productivity appear mainly sector specific. Also differences in the level of development affect the effectiveness of knowledge sources. In the food processing sector, firms with higher educated managers are more productive, and in least-developed countries, additionally those with technology licenses and imported machinery and equipment. In the capital-intensive textiles sector, productivity is higher in firms that conduct R&D. In the garments and leather products sector, higher education of the managers, licensing, and R&D raise productivity. Y1 - 2014 U6 - https://doi.org/10.1093/icc/dtt006 SN - 1464-3650 (E-Journal); 0960-6491 (Print) VL - 23 IS - 1 SP - 1 EP - 23 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Hoyler, Friedrich A1 - Corminboeuf, F. A1 - Jolie, J. T1 - Kp=4+ double-gvibration in 164Dy / F. Corminboeuf ; J. Jolie ... F. Hoyler ... JF - Physical review / C. 56 (1997), H. 3 Y1 - 1997 SN - 0556-2813 SP - R1201 ER - TY - JOUR A1 - Svaneborg, Carsten A1 - Karimi-Varzaneh, Hossein Ali A1 - Hojdis, Nils A1 - Fleck, Franz A1 - Everaers, Ralf T1 - Kremer-Grest Models for Universal Properties of Specific Common Polymer Species JF - Soft Condensed Matter N2 - The Kremer-Grest (KG) bead-spring model is a near standard in Molecular Dynamic simulations of generic polymer properties. It owes its popularity to its computational efficiency, rather than its ability to represent specific polymer species and conditions. Here we investigate how to adapt the model to match the universal properties of a wide range of chemical polymers species. For this purpose we vary a single parameter originally introduced by Faller and Müller-Plathe, the chain stiffness. Examples include polystyrene, polyethylene, polypropylene, cis-polyisoprene, polydimethylsiloxane, polyethyleneoxide and styrene-butadiene rubber. We do this by matching the number of Kuhn segments per chain and the number of Kuhn segments per cubic Kuhn volume for the polymer species and for the Kremer-Grest model. We also derive mapping relations for converting KG model units back to physical units, in particular we obtain the entanglement time for the KG model as function of stiffness allowing for a time mapping. To test these relations, we generate large equilibrated well entangled polymer melts, and measure the entanglement moduli using a static primitive-path analysis of the entangled melt structure as well as by simulations of step-strain deformation of the model melts. The obtained moduli for our model polymer melts are in good agreement with the experimentally expected moduli. Y1 - 2018 IS - 1606.05008 ER - TY - JOUR A1 - Everaers, Ralf A1 - Karimi-Varzaneh, Hossein Ali A1 - Fleck, Franz A1 - Hojdis, Nils A1 - Svaneborg, Carsten T1 - Kremer–Grest Models for Commodity Polymer Melts: Linking Theory, Experiment, and Simulation at the Kuhn Scale JF - Macromolecules N2 - The Kremer–Grest (KG) polymer model is a standard model for studying generic polymer properties in molecular dynamics simulations. It owes its popularity to its simplicity and computational efficiency, rather than its ability to represent specific polymers species and conditions. Here we show that by tuning the chain stiffness it is possible to adapt the KG model to model melts of real polymers. In particular, we provide mapping relations from KG to SI units for a wide range of commodity polymers. The connection between the experimental and the KG melts is made at the Kuhn scale, i.e., at the crossover from the chemistry-specific small scale to the universal large scale behavior. We expect Kuhn scale-mapped KG models to faithfully represent universal properties dominated by the large scale conformational statistics and dynamics of flexible polymers. In particular, we observe very good agreement between entanglement moduli of our KG models and the experimental moduli of the target polymers. Y1 - 2020 U6 - https://doi.org/10.1021/acs.macromol.9b02428 SN - 1520-5835 VL - 53 IS - 6 SP - 1901 EP - 1916 PB - ACS Publications CY - Washington, DC ER - TY - JOUR A1 - Schulte-Zurhausen, Manfred A1 - Poznanska, K. T1 - Kryteria klasyfikacji malych i srednich przedsiebiorstw = Kriterien zur Klassifizierung von kleinen und mittleren Unternehmen JF - Przeglad Organizacji (1994) Y1 - 1994 SP - 24 EP - 27 ER - TY - JOUR A1 - Mischke, Winfried T1 - Kurzkommentierung der §§ 433, 436, 446 - 453, 474 - 479 BGB JF - LexisNexis : Elektronische Ressource / Recht (2009) Y1 - 2009 ER - TY - JOUR A1 - Meyer, Carolin A1 - Gaalen, Kerstin van A1 - Leschinger, Tim A1 - Scheyerer, Max J. A1 - Neiss, Wolfram F. A1 - Staat, Manfred A1 - Müller, Lars P. A1 - Wegmann, Kilian T1 - Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement JF - BioMed Research International Y1 - 2019 U6 - https://doi.org/10.1155/2019/9232813 SP - Article ID 9232813 ER - TY - JOUR A1 - Mayer, Claudia T1 - L'Estétique et le pouvoir: Le discours chaotique de l'Allemagne unifiée JF - Canadian review of comparative literature : CRCL = Revue canadienne de littérature comparée : RCLC / Canadian Comparative Literature Association. 24 (1997), H. 2 Y1 - 1997 SN - 0319-051X SP - 297 EP - 317 ER - TY - CHAP A1 - Schneckenburger, N. A1 - Franzen, N. A1 - Gligorevic, Snjezana A1 - Schnell, M. T1 - L-band compatibility of LDACS1 T2 - IEEE/AIAA 30th Digital Avionics Systems Conference (DASC) : 16 - 20 Oct. 2011, Seattle, Wash. Y1 - 2011 SN - 978-1-61284-797-9 SN - 2155-7195 SP - 4C3-1 EP - 4C3-11 ER - TY - CHAP A1 - Gligorevic, Snjezana A1 - Schneckenburger, N. A1 - Franzen, N. A1 - Schnell, Michael A1 - Müller, S. A1 - Günzel, H. T1 - L-Band compatibility of LDACS1 T2 - 3rd CEAS Air and Space Conference, 24 - 28 October 2011, Venezia, Italy Y1 - 2011 SP - 1 EP - 8 ER - TY - CHAP A1 - Schnell, Michael A1 - Franzen, Nico A1 - Gligorevic, Snjezana T1 - L-DACS1 laboratory demonstrator development and compatibility measurement set-up T2 - IEEE/AIAA 29th Digital Avionics Systems Conference (DASC) : 3 - 7 Oct. 2010, Salt Lake City, Utah Y1 - 2010 SN - 9781424466160 ; 9781424466184 SP - 3E3-1 EP - 3E3-11 ER - TY - BOOK A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - Label-free biosensing: advanced materials, devices and applications Y1 - 2018 SN - 978-3-319-75219-8 PB - Springer CY - Cham ER - TY - JOUR A1 - Poghossian, Arshak A1 - Ingebrandt, S. A1 - Abouzar, Maryam H. A1 - Schöning, Michael Josef T1 - Label-free detection of charged macromolecules by using a field-effect-based sensor platform: Experiments and possible mechanisms of signal generation JF - Applied Physics A: Materials Science & Processing. 87 (2007), H. 3 Y1 - 2007 SN - 0947-8396 N1 - Special Issue “From Surface Science to Nanoscale Devices” SP - 517 EP - 524 ER - TY - JOUR A1 - Bronder, Thomas A1 - Wu, Chunsheng A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Label-free detection of DNA hybridization with light-addressable potentiometric sensors: comparison of various DNA-immobilization strategies JF - Procedia Engineering N2 - Light-addressable potentiometric sensors (LAPS) consisting of a p-Si-SiO2 and p-Si-SiO2-Au structure, respectively, have been tested for a label-free electrical detection of DNA (deoxyribonucleic acid) hybridization. Three different strategies for immobilizing single-stranded probe DNA (ssDNA) molecules on a LAPS surface have been studied and compared: (a) immobilization of thiol-modified ssDNA on the patterned Au surface via gold-thiol bond, (b) covalent immobilization of amino-modified ssDNA onto the SiO2 surface functionalized with 3-aminopropyltriethoxysilane and (c) layer-by-layer adsorption of negatively charged ssDNA on a positively charged weak polyelectrolyte layer of poly(allylamine hydrochloride). KW - LAPS KW - lable-free detection KW - DNA hybridization KW - field-effect sensor Y1 - 2014 U6 - https://doi.org/10.1016/j.proeng.2014.11.647 SN - 1877-7058 N1 - EUROSENSORS 2014 ; European Conference on Solid-State Transducers <28, 2014> VL - 87 SP - 755 EP - 758 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Wu, Chunsheng A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Schöning, Michael Josef T1 - Label-free detection of DNA using light-addressable potentiometric sensor modified with a positively charged polyelectrolyte layer JF - Nanoscale N2 - A multi-spot (16 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al–p-Si–SiO2 structure modified with a weak polyelectrolyte layer of PAH (poly(allylamine hydrochloride)) was applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. To achieve a preferentially flat orientation of DNA strands and thus, to reduce the distance between the DNA charge and MLAPS surface, the negatively charged probe single-stranded DNAs (ssDNA) were electrostatically adsorbed onto the positively charged PAH layer using a simple layer-by-layer (LbL) technique. In this way, more DNA charge can be positioned within the Debye length, yielding a higher sensor signal. The surface potential changes in each spot induced due to the surface modification steps (PAH adsorption, probe ssDNA immobilization, hybridization with complementary target DNA (cDNA), non-specific adsorption of mismatched ssDNA) were determined from the shifts of photocurrent–voltage curves along the voltage axis. A high sensor signal of 83 mV was registered after immobilization of probe ssDNA onto the PAH layer. The hybridization signal increases from 5 mV to 32 mV with increasing the concentration of cDNA from 0.1 nM to 5 μM. In contrast, a small signal of 5 mV was recorded in the case of non-specific adsorption of fully mismatched ssDNA (5 μM). The obtained results demonstrate the potential of the MLAPS in combination with the simple and rapid LbL immobilization technique as a promising platform for the future development of multi-spot light-addressable label-free DNA chips with direct electrical readout. Y1 - 2015 U6 - https://doi.org/10.1039/C4NR07225A VL - 14 IS - 7 SP - 6143 EP - 6150 PB - Royal Society of Chemistry (RSC) CY - Cambridge ER - TY - JOUR A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Label-free detection of double-stranded DNA molecules with polyelectrolyte-modified capacitive field-effect sensors T1 - Markierungsfreie Detektion doppelsträngiger DNA Moleküle mit Hilfe von Polyelektrolyt-modifizierten kapazitiven Feldeffekt-Sensoren JF - tm - Technisches Messen N2 - In this study, polyelectrolyte-modified field-effect-based electrolyte-insulator-semiconductor (EIS) devices have been used for the label-free electrical detection of double-stranded deoxyribonucleic acid (dsDNA)molecules. The sensor-chip functionalization with a positively charged polyelectrolyte layer provides the possibility of direct adsorptive binding of negatively charged target DNA oligonucleotides onto theSiO2-chip surface.EIS sensors can be utilized as a tool to detect surface-charge changes; the electrostatic adsorption of oligonucleotides onto the polyelectrolyte layer leads to a measureable surface-potential change. Signals of 39mV have been recorded after the incubation with the oligonucleotide solution. Besides the electrochemical experiments, the successful adsorption of dsDNA onto the polyelectrolyte layer has been verified via fluorescence microscopy. The presented results demonstrate that the signal recording of EISchips, which are modified with a polyelectrolyte layer, canbe used as a favorable approach for a fast, cheap and simple detection method for dsDNA. Y1 - 2017 U6 - https://doi.org/10.1515/teme-2017-0015 VL - 84 IS - 10 SP - 628 EP - 634 PB - De Gruyter CY - Oldenbourg ER - TY - JOUR A1 - Ingebrandt, S. A1 - Han, Y. A1 - Nakamura, F. A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Offenhäusser, A. T1 - Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors JF - Biosensors and Bioelectronics. 22 (2007), H. 12 Y1 - 2007 SN - 0956-5663 SP - 2834 EP - 2840 ER - TY - THES A1 - Bronder, Thomas T1 - Label-free detection of tuberculosis DNA with capacitive field-effect biosensors Y1 - 2020 U6 - https://doi.org/10.17192/z2021.0056 N1 - Dissertation, Universität, Marburg 2020 PB - Philipps-Universität Marburg CY - Marburg ER - TY - JOUR A1 - Schöning, Michael Josef A1 - Bronder, Thomas A1 - Wu, Chunsheng A1 - Scheja, Sabrina A1 - Jessing, Max A1 - Metzger-Boddien, Christoph A1 - Keusgen, Michael A1 - Poghossian, Arshak T1 - Label-Free DNA Detection with Capacitive Field-Effect Devices—Challenges and Opportunities JF - Proceedings N2 - Field-effect EIS (electrolyte-insulator-semiconductor) sensors modified with a positively charged weak polyelectrolyte layer have been applied for the electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge. The EIS sensors are able to detect the existence of target DNA amplicons in PCR (polymerase chain reaction) samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Due to their miniaturized setup, compatibility with advanced micro- and nanotechnologies, and ability to detect biomolecules by their intrinsic molecular charge, those sensors can serve as possible platform for the development of label-free DNA chips. Possible application fields as well as challenges and limitations will be discussed. Y1 - 2017 U6 - https://doi.org/10.3390/proceedings1080719 SN - 2504-3900 N1 - This article belongs to the Proceedings of "Proceedings of the 5th International Symposium on Sensor Science (I3S 2017)" VL - 1 IS - 8 SP - Artikel 719 PB - MDPI CY - Basel ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Pedraza, A. M. A1 - Schöning, Michael Josef A1 - Poghossian, Arshak T1 - Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles JF - Procedia Engineering. 5 (2010) Y1 - 2010 SN - 1877-7058 N1 - Proc. Eurosensors XXIV, September 5–8, 2010, Linz, Austria SP - 918 EP - 921 ER - TY - JOUR A1 - Abouzar, Maryam H. A1 - Poghossian, Arshak A1 - Cherstvy, Andrey G. A1 - Pedraza, Angela M. A1 - Ingebrandt, Sven A1 - Schöning, Michael Josef T1 - Label-free electrical detection of DNA by means of field-effect nanoplate capacitors: Experiments and modeling JF - Physica Status Solidi (a) N2 - Label-free electrical detection of consecutive deoxyribonucleic acid (DNA) hybridization/denaturation by means of an array of individually addressable field-effect-based nanoplate silicon-on-insulator (SOI) capacitors modified with gold nanoparticles (Au-NP) is investigated. The proposed device detects charge changes on Au-NP/DNA hybrids induced by the hybridization or denaturation event. DNA hybridization was performed in a high ionic-strength solution to provide a high hybridization efficiency. On the other hand, to reduce the screening of the DNA charge by counter ions and to achieve a high sensitivity, the sensor signal induced by the hybridization and denaturation events was measured in a low ionic-strength solution. High sensor signals of about 120, 90, and 80 mV were registered after the DNA hybridization, denaturation, and re-hybridization events, respectively. Fluorescence microscopy has been applied as reference method to verify the DNA immobilization, hybridization, and denaturation processes. An electrostatic charge-plane model for potential changes at the gate surface of a nanoplate field-effect sensor induced by the DNA hybridization has been developed taking into account both the Debye length and the distance of the DNA charge from the gate surface. Y1 - 2012 U6 - https://doi.org/10.1002/pssa.201100710 SN - 1862-6319 VL - 209 SP - 925 EP - 934 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Wu, Chunsheng A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Bäcker, Matthias A1 - Schöning, Michael Josef T1 - Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips JF - Physica status solidi A : Applications and materials science N2 - A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al–p-Si–SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent–voltage (I–V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I–V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge. Y1 - 2014 U6 - https://doi.org/10.1002/pssa.201330442 SN - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print) VL - 211 IS - 6 SP - 1423 EP - 1428 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Poghossian, Arshak A1 - Bronder, Thomas A1 - Scheja, S. A1 - Wu, Chunsheng A1 - Metzger-Boddien, C. A1 - Keusgen, M. A1 - Schöning, Michael Josef T1 - Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices T2 - Procedia Engineering N2 - A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process. Y1 - 2016 U6 - https://doi.org/10.1016/j.proeng.2016.11.512 SN - 1877-7058 N1 - Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary VL - Vol. 168 SP - 514 EP - 517 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Poghossian, Arshak A1 - Bronder, Thomas A1 - Wu, Chunsheng A1 - Schöning, Michael Josef T1 - Label-free sensing of biomolecules by their intrinsic molecular charge using field-effect devices T2 - Semiconductor Micro- and Nanoelectonics : Proceedings of the tenth international conference, Yerevan, Armenia, September 11-13 Y1 - 2015 SN - 978-5-8084-1991-9 SP - 61 EP - 63 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Label-free sensing of biomolecules with field-effect devices for clinical applications JF - Electroanalysis N2 - Among the variety of transducer concepts proposed for label-free detection of biomolecules, the semiconductor field-effect device (FED) is one of the most attractive platforms. As medical techniques continue to progress towards diagnostic and therapies based on biomarkers, the ability of FEDs for a label-free, fast and real-time detection of multiple pathogenic and physiologically relevant molecules with high specificity and sensitivity offers very promising prospects for their application in point-of-care and personalized medicine for an early diagnosis and treatment of diseases. The presented paper reviews recent advances and current trends in research and development of different FEDs for label-free, direct electrical detection of charged biomolecules by their intrinsic molecular charge. The authors are mainly focusing on the detection of the DNA hybridization event, antibody-antigen affinity reaction as well as clinically relevant biomolecules such as cardiac and cancer biomarkers. Y1 - 2014 U6 - https://doi.org/10.1002/elan.201400073 SN - 1521-4109 (E-Journal); 1040-0397 (Print) VL - 26 IS - 6 SP - 1197 EP - 1213 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Bung, Daniel Bernhard ED - Rowinski, Pawel T1 - Laboratory models of free-surface flows T2 - Rivers - physical, fluvial and environmental processes N2 - Hydraulic modeling is the classical approach to investigate and describe complex fluid motion. Many empirical formulas in the literature used for the hydraulic design of river training measures and structures have been developed using experimental data from the laboratory. Although computer capacities have increased to a high level which allows to run complex numerical simulations on standard workstation nowadays, non-standard design of structures may still raise the need to perform physical model investigations. These investigations deliver insight into details of flow patterns and the effect of varying boundary conditions. Data from hydraulic model tests may be used for calibration of numerical models as well. As the field of hydraulic modeling is very complex, this chapter intends to give a short overview on capacities and limits of hydraulic modeling in regard to river flows and hydraulic structures only. The reader shall get a first idea of modeling principles and basic considerations. More detailed information can be found in the references. KW - Physical modeling KW - Similitude KW - Open channels KW - Hydraulic structures Y1 - 2015 SN - 978-3-319-17718-2 ; 978-3-319-17719-9 U6 - https://doi.org/10.1007/978-3-319-17719-9_9 SP - 213 EP - 228 PB - Springer CY - Cham ER - TY - JOUR A1 - Zischank, Wolfgang J. A1 - Heidler, Fridolin A1 - Wiesinger, J. A1 - Metwally, I. A1 - Kern, Alexander A1 - Seevers, M. T1 - Laboratory simulation of direct lightning strokes to a modeled building : measurement of magnetic fields and included voltages JF - Journal of electrostatics. 60 (2004), H. 2 - 4 Y1 - 2004 SN - 0304-3886 N1 - ISSN der E-Ausg.: 0304-3886 SP - 223 EP - 232 ER - TY - JOUR A1 - Schwarzer, Klemens A1 - Werner, M. A1 - Hartz, T. T1 - Lacasa - an instrument for the energy analysis and optimisation of buildings including technical equipment JF - Proceedings / organised by: ISES Europe ... [Ed.: Deutsche Gesellschaft für Sonnenenergie e.V. - DGS, Munich ; PSE GmbH - Forschung Entwicklung Marketing, Freiburg]. - Vol. 2 Y1 - 2004 SN - 3-9809656-2-7 N1 - EuroSun <5, 2004, Freiburg, Breisgau> ; Internationales Sonnenforum <14, 2004, Freiburg, Breisgau> ; Deutsche Gesellschaft für Sonnenenergie ; CD-ROM-Ausg.: ISBN 3-9809656-4-3 SP - 2-489-2-494 PB - PSE CY - Freiburg [Breisgau] ER - TY - BOOK A1 - Schwarzer, Klemens T1 - Lacasa : Einsatz von MATLAB-Simulink zur energetischen Analyse und Optimierung von Alt- und Neubauten inklusive Heizungs-, Lüftungs- und Klimatechnik / Hrsg.: FIA-Projekt, Forschungs-Informations-Austausch im Fachinstitut Gebäude-Klima e.V. Projekt: Solar-Institut Jülich an der Fachhochschule Aachen Y1 - 2004 SN - 3-938210-07-9 PB - FIA-Projekt im Fachinst. Gebäude-Klima CY - Bietigheim-Bissingen ER - TY - JOUR A1 - Mertens, Josef T1 - Laminar flow for supersonic transports JF - Proceedings : March 16 - 18, 1992, Congress Centrum, Hamburg, Federal Republic of Germany / organized jointly by: Deutsche Gesellschaft für Luft- und Raumfahrt e.V. ... [Programme committee J. Szodruch ...] Y1 - 1992 SN - 3-922010-73-3 N1 - DGLR-Bericht ; 92,06 SP - 319 EP - 323 PB - DGLR CY - Bonn ER - TY - JOUR A1 - Wittmann, Klaus A1 - Ulamec, S A1 - Richter, L T1 - Lander Systems for Planetary Missions JF - Laboratory astrophysics and space research / ed. by P. Ehrenfreund Y1 - 1999 SN - 0-7923-5338-2 N1 - Serie Astrophysics and space science library 236 SP - 597 EP - 621 PB - Kluwer CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Ferrein, Alexander A1 - Beck, Daniel A1 - Lakemeyer, Gerhard T1 - Landmark-Based Representations for Navigating Holonomic Soccer Robots / Beck, Daniel ; Ferrein, Alexander ; Lakemeyer, Gerhard JF - RoboCup 2008 : robot soccer world cup XII / Luca Iocchi ... (eds.) Y1 - 2009 SN - 978-3-642-02921-9 N1 - Lecture Notes in Computer Science ; 5399 SP - 25 EP - 36 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Dantism, Shahriar A1 - Röhlen, Desiree A1 - Dahmen, Markus A1 - Wagner, Torsten A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - LAPS-based monitoring of metabolic responses of bacterial cultures in a paper fermentation broth JF - Sensors and Actuators B: Chemical N2 - As an alternative renewable energy source, methane production in biogas plants is gaining more and more attention. Biomass in a bioreactor contains different types of microorganisms, which should be considered in terms of process-stability control. Metabolically inactive microorganisms within the fermentation process can lead to undesirable, time-consuming and cost-intensive interventions. Hence, monitoring of the cellular metabolism of bacterial populations in a fermentation broth is crucial to improve the biogas production, operation efficiency, and sustainability. In this work, the extracellular acidification of bacteria in a paper-fermentation broth is monitored after glucose uptake, utilizing a differential light-addressable potentiometric sensor (LAPS) system. The LAPS system is loaded with three different model microorganisms (Escherichia coli, Corynebacterium glutamicum, and Lactobacillus brevis) and the effect of the fermentation broth at different process stages on the metabolism of these bacteria is studied. In this way, different signal patterns related to the metabolic response of microorganisms can be identified. By means of calibration curves after glucose uptake, the overall extracellular acidification of bacterial populations within the fermentation process can be evaluated. Y1 - 2020 U6 - https://doi.org/10.1016/j.snb.2020.128232 SN - 0925-4005 VL - 320 IS - Art. 128232 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Seefeldt, Patric A1 - Bauer, Waldemar A1 - Dachwald, Bernd A1 - Grundmann, Jan Thimo A1 - Straubel, Marco A1 - Sznajder, Maciej A1 - Tóth, Norbert A1 - Zander, Martin E. T1 - Large lightweight deployable structures for planetary defence: solar sail propulsion, solar concentrator payloads, large-scale photovoltaic power T2 - 4th IAA Planetary Defense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy Y1 - 2015 N1 - IAA-PDC-15-P-20 ER - TY - JOUR A1 - Roesner, Andreas A1 - Scheik, Sven A1 - Olowinsky, Alexander A1 - Gillner, Arnold A1 - Reisgen, Uwe A1 - Schleser, Markus T1 - Laser assisted joining of plastic metal hybrids JF - Lasers in manufacturing 2011 : proceedings of the sixth International WLT Conference on Lasers in Manufacturing, Munich, May 23 - 26 2011. (Physics procedia ; Vol. 12 (2011), Part B) Y1 - 2011 SN - 1875-3892 (E-Journal); 1875-3884 (Print) SP - 370 EP - 377 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reisgen, Uwe A1 - Olschok, Simon A1 - Jakobs, Stefan A1 - Schleser, Markus A1 - Mokrov, Oleg A1 - Rossiter, Eduardo T1 - Laser beam submerged arc hybrid welding JF - Physics procedia N2 - The laser beam-submerged arc hybrid welding method originates from the knowledge that, with increasing penetration depth, the laser beam process has a tendency to pore formation in the lower weld regions. The coupling with the energy-efficient submerged-arc process improves degassing and reduces the tendency to pore formation. The high deposition rate of the SA process in combination with the laser beam process offers, providing the appropriate choice of weld preparation, the possibility of welding plates with a thickness larger than 20° mm in a single pass, and also of welding thicker plates with the double-sided single pass technique. Y1 - 2012 U6 - https://doi.org/10.1016/j.phpro.2012.10.016 SN - 1875-3892 N1 - Part of special issue "Laser assisted net shape engineering 7 (LANE 2012)" VL - 39 SP - 75 EP - 83 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Ferrein, Alexander A1 - Strack, Andreas A1 - Lakemeyer, Gerhard T1 - Laser-Based Localization with Sparse Landmarks / Strack, Andreas ; Ferrein, Alexander ; Lakemeyer, Gerhard JF - RoboCup 2005: Robot Soccer World Cup IX Y1 - 2006 SN - 978-3-540-35437-6 N1 - Lecture Notes in Computer Science ; 4020 SP - 569 EP - 576 PB - Springer CY - Berlin ER - TY - JOUR A1 - Ermolenko, Y. E. A1 - Yoshinobu, T. A1 - Mourzina, Y. G. A1 - Vlasov, Y. G. A1 - Schöning, Michael Josef A1 - Iwasaki, H. T1 - Laserscanned transducer (LSST) as a multisensor system JF - Sensors and Actuators B. 103 (2004), H. 1-2 Y1 - 2004 SN - 0925-4005 SP - 457 EP - 462 ER - TY - JOUR A1 - Gebhardt, Andreas T1 - Laserwelding with fillerwire JF - LIA handbook of laser material processing / Laser Institute of America Y1 - 2001 SN - 3-540-41770-2 N1 - Chapter 11.2.12 CY - Orlando, Florida ER -