TY - JOUR A1 - Dachwald, Bernd A1 - Baturkin, Volodymyr A1 - Coverstone, Victoria L. A1 - Dietrich, Benjamin A1 - Garbe, Gregory P. A1 - Görlich, Marianne A1 - Leipold, Manfred A1 - Lura, Franz A1 - Macdonald, Malcolm A1 - McInnes, Colin R. A1 - Mengali, Giovanni A1 - Quatra, Alessandro A. A1 - Rios-Reyes, Leonel A1 - Scheeres, Daniel J. A1 - Seboldt, Wolfgang A1 - Wie, Bong T1 - Potential Effects of Optical Solar Sail Degradation on Interplanetary Trajectory Design JF - Astrodynamics 2005 : proceedings of the AAS/AIAA astrodynamics conference held August 7 - 11, 2005, South Lake Tahoe, California / ed. by Bobby G. Williams. - Pt. 3. - (Advances in the astronautical sciences ; 123,3) Y1 - 2006 UR - http://www.spacesailing.net/paper/200508_LakeTahoe_Dachwald+.pdf SN - 0-87703-527-X N1 - Astrodynamics Conference <2005, South Lake Tahoe, Calif.> ; American Astronautical Society ; Number: AAS-05-413 SP - 2569 EP - 2592 PB - Univelt CY - San Diego, Calif. ER - TY - JOUR A1 - Tran, Thanh Ngoc A1 - Kreißig, R. A1 - Vu, Duc Khoi A1 - Staat, Manfred T1 - Upper bound limit and shakedown analysis of shells using the exact Ilyushin yield surface JF - Computer & Structures. 86 (2008) Y1 - 2008 SN - 0045-7949 SP - 1683 EP - 1695 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, W. T1 - Optimization of Interplanetary Rendezvous Trajectories for Solar Sailcraft Using a Neurocontroller JF - A collection of technical papers / AIAA Astrodynamics Specialist Conference : Monterey, California, 5 - 8 August 2002. - Vol. 2 Y1 - 2002 SN - 1-56347-549-9 N1 - Astrodynamics Specialist Conference <2002, Monterey, Calif.> American Institute of Aeronautics and Astronautics ; AIAA paper number: AIAA-2002-4989 SP - 1263 EP - 1270 PB - American Institute of Aeronautics and Astronautics CY - Reston, Va. ER - TY - JOUR A1 - Staat, Manfred A1 - Tran, Thanh Ngoc A1 - Kreißig, R. T1 - Load bearing capacity of thin shell structures made of elastoplastic material by direct methods JF - Technische Mechanik. 28 (2008), H. 3-4 Y1 - 2008 SP - 299 EP - 309 ER - TY - JOUR A1 - Tran, Thanh Ngoc A1 - Kreißig, R. A1 - Staat, Manfred T1 - Probabilistic limit and shakedown analysis of thin plates and shells JF - Structural safety. 31 (2009), H. 1 Y1 - 2009 SN - 0167-4730 SP - 1 EP - 18 PB - - ER - TY - JOUR A1 - Dachwald, Bernd A1 - McDonald, Malcolm A1 - McInnes, Colin R. A1 - Mengali, Giovanni T1 - Impact of Optical Degradation on Solar Sail Mission Performance JF - Journal of Spacecraft and Rockets. 44 (2007), H. 4 Y1 - 2007 SN - 0022-4650 N1 - 2. ISSN: 1533-6794 SP - 740 EP - 749 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Wi, Bong T1 - Solar Sail Kinetic Energy Impactor Trajectory Optimization for an Asteroid-Deflection Mission JF - Journal of Spacecraft and Rockets. 44 (2007), H. 4 Y1 - 2007 SN - 0022-4650 N1 - 2. ISSN: 1533-6794 SP - 755 EP - 764 ER - TY - JOUR A1 - Dachwald, Bernd T1 - Minimum Transfer Times for Nonperfectly Reflecting Solar Sailcraft JF - Journal of Spacecraft and Rockets. 41 (2004), H. 4 Y1 - 2004 SN - 0022-4650 N1 - 2. ISSN: 1533-6794 SP - 693 EP - 695 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Mengali, Giovanni A1 - Quarta, Alessandrao A. A1 - Macdonald, Malcolm T1 - Parametric Model and Optimal Control of Solar Sails with Optical Degradation JF - Journal of guidance, control, and dynamics. 29 (2006), H. 5 Y1 - 2006 SN - 0162-3192 N1 - 2. ISSN: 0731-5090 SP - 1170 EP - 1178 ER - TY - JOUR A1 - Dachwald, Bernd T1 - Optimal Solar Sail Trajectories for Missions to the Outer Solar System JF - Journal of guidance, control, and dynamics. 28 (2005), H. 6 Y1 - 2005 SN - 0162-3192 N1 - 2. ISSN: 0162-3192. - 3. ISSN: 0731-5090 SP - 1187 EP - 1193 ER - TY - JOUR A1 - Dachwald, Bernd T1 - Optimization of Interplanetary Solar Sailcraft Trajectories Using Evolutionary Neurocontrol JF - Journal of guidance, control, and dynamics. 27 (2004), H. 1 Y1 - 2004 SN - 0162-3192 N1 - 2. ISSN: 0162-3192. - 3. ISSN: 0731-5090 SP - 66 EP - 72 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Ohndorf, A. A1 - Gill, E. T1 - Optimization of low-thrust Earth-Moon transfers using evolutionary neurocontrol / Ohndorf, A. ; Dachwald, B. ; Gill, E. JF - IEEE Congress on Evolutionary Computation, 2009. CEC '09. Y1 - 2009 SN - 978-1-4244-2958-5 SP - 358 EP - 364 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, W. A1 - Lämmerzahl, W. T1 - Solar Sail Propulsion: An Enabling Technology for Fundamental Physics Missions JF - Lasers, Clocks and Drag Free Control : Exploration of Relativistic Gravity in Space / by Hansjörg Dittus ..., eds. - ( Astrophysics and Space Science Library ; 349) Y1 - 2008 SN - 978-3-540-34376-9 SP - 379 EP - 398 PB - Springer CY - Berlin [u.a.] ER - TY - JOUR A1 - Stadler, Andreas M. A1 - Garvey, G. J. A1 - Bocahut, A. A1 - Sacquin-Mora, S. A1 - Digel, Ilya A1 - Schneider, G. J. A1 - Natali, F. A1 - Artmann, Gerhard A1 - Zaccai, G. T1 - Thermal fluctuations of haemoglobin from different species : adaptation to temperature via conformational dynamics JF - Journal of the Royal Society Interface N2 - Thermodynamic stability, configurational motions and internal forces of haemoglobin (Hb) of three endotherms (platypus, Ornithorhynchus anatinus; domestic chicken, Gallus gallus domesticus and human, Homo sapiens) and an ectotherm (salt water crocodile, Crocodylus porosus) were investigated using circular dichroism, incoherent elastic neutron scattering and coarse-grained Brownian dynamics simulations. The experimental results from Hb solutions revealed a direct correlation between protein resilience, melting temperature and average body temperature of the different species on the 0.1 ns time scale. Molecular forces appeared to be adapted to permit conformational fluctuations with a root mean square displacement close to 1.2 Å at the corresponding average body temperature of the endotherms. Strong forces within crocodile Hb maintain the amplitudes of motion within a narrow limit over the entire temperature range in which the animal lives. In fully hydrated powder samples of human and chicken, Hb mean square displacements and effective force constants on the 1 ns time scale showed no differences over the whole temperature range from 10 to 300 K, in contrast to the solution case. A complementary result of the study, therefore, is that one hydration layer is not sufficient to activate all conformational fluctuations of Hb in the pico- to nanosecond time scale which might be relevant for biological function. Coarse-grained Brownian dynamics simulations permitted to explore residue-specific effects. They indicated that temperature sensing of human and chicken Hb occurs mainly at residues lining internal cavities in the β-subunits. Y1 - 2012 U6 - https://doi.org/10.1098/rsif.2012.0364 SN - 1742-5689 VL - 9 IS - 76 SP - 2845 EP - 2855 PB - The Royal Society CY - London ER - TY - JOUR A1 - Demirci, Taylan A1 - Kurulgan Demirci, Eylem A1 - Trzewik, Jürgen A1 - Linder, Peter A1 - Digel, Ilya A1 - Artmann, Gerhard A1 - Sakizli, Meral A1 - Temiz Artmann, Aysegül T1 - Gene expression profile analysis of 3T3/NIH fibroblasts after one hour mechanical stress JF - IUBMB Life. 61 (2009), H. 3 Y1 - 2009 SN - 1521-6543 N1 - Abstracts: Turkish Society of Molecular Medicine, Third International Congress of Molecular Medicine, May 5-8, 2009, Istanbul, Turkey SP - 311 EP - 312 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Becker, C. A1 - Wallang, C. A1 - Artmann, Gerhard A1 - Jakse, G. T1 - Mechanotransduction-bioreactor for tissue engineering of a ureter prosthesis JF - International Journal of Artificial Organs, The Y1 - 2008 SN - 0391-3988 N1 - Abstracts from the XXXV Congress of the European Society for Artificial Organs: 'Towards Future Biomedical Technologies' - ORAL PRESENTATIONS VL - 31 IS - 7 SP - 583 EP - 583 ER - TY - JOUR A1 - Erbayraktar, Zubeyde A1 - Yilmaz, Osman A1 - Temiz Artmann, Aysegül A1 - Cehreli, Ruksan A1 - Coker, Canan T1 - Effects of Selenium Supplementation on Antioxidant Defense and Glucose Homeostasis in Experimental Diabetes Mellitus JF - Biological Trace Element Research Y1 - 2007 SN - 1559-0720 VL - 118 IS - 3 SP - 217 EP - 226 ER - TY - JOUR A1 - Demirci, T. A1 - Trzewik, J. A1 - Linder, Peter A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül T1 - Mechanical Stimulation of 3T3 Fibroblasts Activates Genes: Real Time PCR Products and Suppliers by Comparison JF - Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2 Y1 - 2004 SN - 0932-4666 SP - 1046 EP - 1047 ER - TY - JOUR A1 - Demirci, T. A1 - Trzewik, J. A1 - Linder, Peter A1 - Digel, Ilya A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül T1 - Mechanical Stimulation of 3T3 Fibroblasts Activates Genes: ITGB5 and p53 Responses as Quantified on the mRNA Level JF - Biomedizinische Technik . 49 (2004), H. Erg.-Bd. 2 Y1 - 2004 SN - 0932-4666 SP - 1030 EP - 1031 ER - TY - JOUR A1 - Sadykov, Rustam A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül A1 - Porst, Dariusz A1 - Linder, Peter A1 - Kayser, Peter A1 - Artmann, Gerhard A1 - Savitskaya, Irina A1 - Zhubanova, Azhar T1 - Oral lead exposure induces dysbacteriosis in rats JF - Journal of Occupational Health. 51 (2009) (2009), H. 1 Y1 - 2009 SN - 1348-9585 SP - 64 EP - 73 ER - TY - JOUR A1 - Temiz Artmann, Aysegül A1 - Saklamaz, Ali A1 - Comlekci, Abdurrahman A1 - Caliskan, Sezer T1 - The beneficial effects of lipid-lowering drugs beyond lipid-lowering effects: A comparative study with pravastatin, atorvastatin, and fenofibrate in patients with type IIa and type IIb hyperlipidemia / Saklamaz, Ali ; Comlekci, Abdurrahman ; Temiz, Aysegu JF - Metabolism. 54 (2005), H. 5 Y1 - 2005 SN - 0026-0495 SP - 677 EP - 681 ER - TY - BOOK A1 - Digel, Ilya A1 - Zhubanova, Azhar Ahmetovna A1 - Akimbekov, Nuraly S. T1 - Visual Virology Y1 - 2012 SN - 978-601-247-298-1 N1 - Text kasachisch, russisch, englisch CY - Almaty ER - TY - JOUR A1 - Staat, Manfred A1 - Vu, Duc Khoi T1 - Limit analysis of flaws in pressurized pipes and cylindrical vessels Part II: Circumferential defects JF - Engineering Fracture Mechanics ; 97(2013), H. 1 N2 - Upper and lower bound theorems of limit analyses have been presented in part I of the paper. Part II starts with the finite element discretization of these theorems and demonstrates how both can be combined in a primal–dual optimization problem. This recently proposed numerical method is used to guide the development of a new class of closed-form limit loads for circumferential defects, which show that only large defects contribute to plastic collapse with a rapid loss of strength with increasing crack sizes. The formulae are compared with primal–dual FEM limit analyses and with burst tests. Even closer predictions are obtained with iterative limit load solutions for the von Mises yield function and for the Tresca yield function. Pressure loading of the faces of interior cracks in thick pipes reduces the collapse load of circumferential defects more than for axial flaws. Axial defects have been treated in part I of the paper. Y1 - 2012 U6 - https://doi.org/10.1016/j.engfracmech.2012.05.017 SN - 0013-7944 VL - 97 SP - 314 EP - 333 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Doorschodt, B. M. A1 - Schreinemachers, M. C. J. M. A1 - Behbahani, Mehdi A1 - Florquin, S. A1 - Weis, J. A1 - Staat, Manfred A1 - Tolba, R. H. T1 - Hypothermic machine perfusion of kidney grafts: which pressure is preferred JF - Annals of Biomedical Engineering. 39 (2011), H. 3 Y1 - 2011 SN - 1573-9686 SP - 1051 EP - 1059 PB - Springer CY - Berlin ER - TY - JOUR A1 - Amin, Rashid A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard A1 - Lazarovici, Philip A1 - Lelkes, Peter I. T1 - Permeability of an In Vitro Model of Blood Brain Barrier (BBB) JF - 13th International Conference on Biomedical Engineering / Lim, Chwee Teck [Ed.] Y1 - 2009 SN - 978-3-540-92841-6 N1 - IFMBE Proceedings ; 23, Track 1 ; ICBME 2008 3–6 December 2008 Singapore SP - 81 EP - 84 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Tran, L. A1 - Jockenhövel, S. A1 - Behr, M. A1 - Mottaghy, K. T1 - Numerical prediction of thrombocyte reactions for application to a vascular flow model JF - British Journal of Surgery Y1 - 2011 SN - 1365-2168 N1 - 46th Congress of the European Society for Surgical Research, Aachen, Germany, 25-28 May 2011 ; ESSR Abstracts 2011 ; Oral Sessions OP10-5 VL - 98 IS - S5 SP - S17 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Tran, L. A1 - Waluga, C. A1 - Behr, M. A1 - Oedekoven, B. A1 - Mottaghy, K. T1 - Model-based Numerical Analysis of Platelet Adhesion, Thrombus Growth and Aggregation for Assist Devices JF - The International Journal of Artificial Organs. 32 (2009), H. 7 Y1 - 2009 SN - 0391-3988 N1 - Abstracts - Oral Presentations: XXXVI Annual ESAO Congress, 2-5 September 2009, Compiègne - France; European Society of Artificial Organs (ESAO), Compiegne, France, September 2-5, 2009 SP - 398 EP - 398 ER - TY - JOUR A1 - Leimena, W. A1 - Artmann, Gerhard A1 - Dachwald, Bernd A1 - Temiz Artmann, Aysegül A1 - Gossmann, Matthias A1 - Digel, Ilya T1 - Feasibility of an in-situ microbial decontamination of an ice-melting probe JF - Eurasian Chemico-Technological Journal. 12 (2010), H. 2 Y1 - 2010 SN - 1562-3920 SP - 145 EP - 150 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Nam, J. A1 - Waluga, C. A1 - Behr, M. A1 - Pasquali, M. A1 - Mottaghy, K. T1 - Modeling and Numerical Analysis of Platelet Activation, Adhesion and Aggregation in Artificial Organs Y1 - 2010 U6 - https://doi.org/10.1097/01.mat.0000369377.65122.a3 N1 - Posterpresentation American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 ER - TY - JOUR A1 - Jansen, S. V. A1 - Behbahani, Mehdi A1 - Laumen, M. A1 - Kaufmann, T. A1 - Hormes, M. A1 - Behr, M. A1 - Schmitz-Rode, T. A1 - Steinseifer, U. T1 - Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation Y1 - 2010 N1 - Posterpresentation ; American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 ER - TY - JOUR A1 - Nam, J. A1 - Arora, D. A1 - Behbahani, Mehdi A1 - Probst, M. A1 - Benkowski, R. A1 - Behr, M. A1 - Pasquali, M. T1 - New computational method in hemolysis analysis for artificial heart pump Y1 - 2010 N1 - Posterpresentation ; American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Probst, M. A1 - Mai, A. A1 - Behr, M. A1 - Tran, L. A1 - Vonderstein, K. A1 - Mottaghy, K. T1 - Numerical Prediction of Blood Damage in Biomedical Devices Y1 - 2010 N1 - Posterpresentation ; Biomedica Congress, Aachen, March 17-18, 2010 ER - TY - JOUR A1 - Probst, M. A1 - Behbahani, Mehdi A1 - Borrmann, E. A1 - Elgeti, S. A1 - Nicolai, M. A1 - Behr, M. T1 - Hemodynamic Modeling for Numerical Analysis and Design of Medical Devices Y1 - 2010 N1 - Posterpresentation ; NIC Symposium 2010 ; 24 - 25 February 2010 Jülich, Germany ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Waluga, C. A1 - Stock, S. A1 - Mai, A. A1 - Bergmann, B. A1 - Behr, M. A1 - Tran, L. A1 - Vonderstein, K. A1 - Scheidt, H. A1 - Oedekoven, B. A1 - Mottaghy, K. T1 - Modelling and Numerical Analysis of Platelet Reactions and Surface Thrombus Growth Y1 - 2009 N1 - Posterpresentation ; European Society of Biomaterials (ESB), Lausanne, Switzerland, September 7-10, 2009 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Mai, A. A1 - Bergmann, B. A1 - Waluga, C. A1 - Behr, M. A1 - Tran, L. A1 - Vonderstein, K. A1 - Mottaghy, K. T1 - Modeling and Numerical Simulation of Blood Damage Y1 - 2010 N1 - Posterpresentation ; Umbrella Symposium "Modelling and Simulation in Medicine, Engineering and Sciences", Forschungszentrum Jülich, January 18-20, 2010 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Waluga, C. A1 - Arlt, S. A1 - Behr, M. A1 - Mottaghy, K. T1 - Computational Analysis of Platelet Aggregation in a Taylor-Couette System JF - The International Journal of Artificial Organs. 31 (2008), H. 7 Y1 - 2008 SN - 0391-3988 N1 - Posterpresentation ; European Society of Artificial Organs (ESAO), Geneva, Switzerland SP - 643 ER - TY - JOUR A1 - Behbahani, Mehdi A1 - Mai, A. A1 - Waluga, C. A1 - Bergmann, B. A1 - Tran, L. A1 - Vonderstein, K. A1 - Behr, M. A1 - Mottaghy, K. T1 - Numerical Modeling of Flow-Related Thrombus Formation under Physiological and Non-Physiological Flow Conditions JF - Acta Physiologica Y1 - 2010 SN - 1748-1716 N1 - Joint Congress of the Scandinavian and German Physiological Societies, Copenhagen, Denmark, March 27-30, 2010 VL - 198 IS - Supplement 677 SP - 185 ER - TY - JOUR A1 - Novacek, V. A1 - Tran, Thanh Ngoc A1 - Klinge, U. A1 - Tolba, R. H. A1 - Staat, Manfred A1 - Bronson, D. G. A1 - Miesse, A. M. A1 - Whiffen, J. A1 - Turquier, F. T1 - Finite element modelling of stapled colorectal end-to-end anastomosis : Advantages of variable height stapler design JF - Journal of Biomechanics N2 - The impact of surgical staplers on tissues has been studied mostly in an empirical manner. In this paper, finite element method was used to clarify the mechanics of tissue stapling and associated phenomena. Various stapling modalities and several designs of circular staplers were investigated to evaluate the impact of the device on tissues and mechanical performance of the end-to-end colorectal anastomosis. Numerical simulations demonstrated that a single row of staples is not adequate to resist leakage due to non-linear buckling and opening of the tissue layers between two adjacent staples. Compared to the single staple row configuration, significant increase in stress experienced by the tissue at the inner staple rows was observed in two and three rows designs. On the other hand, adding second and/or third staple row had no effect on strain in the tissue inside the staples. Variable height design with higher staples in outer rows significantly reduced the stresses and strains in outer rows when compared to the same configuration with flat cartridge. KW - Variable height stapler design KW - Anastomotic leakage KW - Finite element modelling KW - End-to-end colorectal anastomosis KW - Surgical staplers Y1 - 2012 U6 - https://doi.org/10.1016/j.jbiomech.2012.07.021 SN - 1873-2380 VL - 45 IS - 115 SP - 2693 EP - 2697 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Nguyen, Nhu Huynh A1 - Duong, Minh Tuan A1 - Tran, Thanh Ngoc A1 - Pham, Phu Tinh A1 - Grottke, O. A1 - Tolba, R. A1 - Staat, Manfred T1 - Influence of a freeze–thaw cycle on the stress–stretch curves of tissues of porcine abdominal organs JF - Journal of Biomechanics N2 - The paper investigates both fresh porcine spleen and liver and the possible decomposition of these organs under a freeze–thaw cycle. The effect of tissue preservation condition is an important factor which should be taken into account for protracted biomechanical tests. In this work, tension tests were conducted for a large number of tissue specimens from twenty pigs divided into two groups of 10. Concretely, the first group was tested in fresh state; the other one was tested after a freeze-thaw cycle which simulates the conservation conditions before biomechanical experiments. A modified Fung model for isotropic behavior was adopted for the curve fitting of each kind of tissues. Experimental results show strong effects of the realistic freeze–thaw cycle on the capsule of elastin-rich spleen but negligible effects on the liver which virtually contains no elastin. This different behavior could be explained by the autolysis of elastin by elastolytic enzymes during the warmer period after thawing. Realistic biomechanical properties of elastin-rich organs can only be expected if really fresh tissue is tested. The observations are supported by tests of intestines. KW - Autolysis KW - Decomposition KW - Freeze–thaw process KW - Spleen KW - Liver Y1 - 2012 U6 - https://doi.org/10.1016/j.jbiomech.2012.07.008 SN - 1873-2380 VL - 45 IS - 14 SP - 2382 EP - 2386 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. T1 - Can vascular function be assessed by the interpretation of retinal vascular diameter changes? JF - Investigative Ophthalmology & Visual Science, IOVS. 52 (2011), H. 1 Y1 - 2011 SN - 0146-0404 SP - 635 EP - 636 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Mücke, Bruno A1 - Vilser, Walthard A1 - Schilling, Rudolf T1 - Effect of aging on retinal artery blood column diameter measured along the vessel axis / Kotliar, Konstantin E. ; Mücke, Bruno ; Vilser, Walthard ; Schilling, Rudolf ; Lanzl, Ines M. JF - Investigative Ophthalmology & Visual Science, IOVS. 49 (2008), H. 5 Y1 - 2008 SN - 0146-0404 SP - 2094 EP - 2102 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Hanssen, Henner A1 - Eberhardt, Karla A1 - Vilser, Walthard A1 - Halle, Martin A1 - Heemann, Uwe A1 - Schmidt-Trucksäss, Arno A1 - Baumann, Marcus T1 - Does increased blood pressure rather than aging influence retinal pulse wave velocity? JF - Investigative Ophthalmology & Visual Science, IOVS N2 - Purpose: It was demonstrated previously that retinal pulse wave velocity (rPWV) as a measure of retinal arterial stiffness is increased in aged anamnestically healthy volunteers compared with young healthy subjects. Using novel methodology of rPWV assessment this finding was confirmed and investigated whether it might relate to the increased blood pressure usually accompanying the aging process, rather than to the aging itself. Methods: A total of 12 young 25.5-year-old (24.0–28.8) [median(1st quartile–3rd quartile)] and 12 senior 68.5-year-old (63.8–71.8) anamnestically healthy volunteers; and 12 senior 63.0-year-old (60.8–65.0) validated healthy volunteers and 12 young 33.0-year-old (29.5–35.0) hypertensive patients were examined. Time-dependent alterations of vessel diameter were assessed by the Dynamic Vessel Analyzer in a retinal artery of each subject. The data were filtered and processed using mathematical signal analysis and rPWVs were calculated. Results: rPWV amounted to 1200 (990-1470) RU (relative units)/s in the hypertensive group and to 1040 (700-2230) RU/s in anamnestically healthy seniors. These differed significantly from rPWVs in young healthy group (410 [280–500] RU/s) and in validated healthy seniors (400 [320–510] RU/s). rPWV associated with age and mean arterial pressure (MAP) in the pooled cohort excluded validated healthy seniors. In a regression model these associations remain when alternately adjusted for MAP and age. When including validated healthy seniors in the pooled cohort only association with MAP remains. Conclusions: Both aging (with not excluded cardiovascular risk factors) and mild hypertension are associated with elevated rPWV. rPWV increases to a similar extent both in young mildly hypertensive subjects and in aged anamnestically healthy persons. Healthy aging is not associated with increased rPWV. Y1 - 2012 U6 - https://doi.org/10.1167/iovs.11-8815 SN - 0146-0404 VL - 53 IS - 4 SP - 2119 EP - 2126 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Nagel, Edgar A1 - Vilser, Walthard A1 - Seidova, Seid-Fatima A1 - Lanzl, Ines T1 - Microstructural alterations of retinal arterial blood column along the vessel axis in systemic hypertension JF - Investigative Ophthalmology & Visual Science, IOVS N2 - Purpose: Image analysis by the retinal vessel analyzer (RVA) observes retinal vessels in their dynamic state online noninvasively along a chosen vessel segment. It has been found that high-frequency diameter changes in the retinal artery blood column along the vessel increase significantly in anamnestically healthy volunteers with increasing age and in patients with glaucoma during vascular dilation. This study was undertaken to investigate whether longitudinal sections of the retinal artery blood column are altered in systemic hypertension. Methods: Retinal arteries of 15 untreated patients with essential arterial hypertension (age, 50.9 ± 11.9 years) and of 15 age-matched anamnestically healthy volunteers were examined by RVA. After baseline assessment, a monochromatic luminance flicker (530–600 nm; 12.5 Hz; 20 s) was applied to evoke retinal vasodilation. Differences in amplitude and frequency of spatial artery blood column diameter change along segments (longitudinal arterial profiles) of 1 mm in length were measured and analyzed using Fourier transformation. Results: In the control group, average reduced power spectra (ARPS) of longitudinal arterial profiles did not differ when arteries changed from constriction to dilation. In the systemic hypertension group, ARPS during constriction, baseline, and restoration were identical and differed from ARPS during dilation (P < 0.05). Longitudinal arterial profiles in both groups showed significant dissimilitude at baseline and restoration (P < 0.05). Conclusions: The retinal artery blood column demonstrates microstructural alterations in systemic hypertension and is less irregular along the vessel axis during vessel dilation. These microstructural changes may be an indication of alterations in vessel wall rigidity, vascular endothelial function, and smooth muscle cells in this disease, leading to impaired perfusion and regulation. Y1 - 2010 U6 - https://doi.org/10.1167/iovs.09-3649 SN - 0146-0404 VL - 51 IS - 4 SP - 2165 EP - 2172 PB - ARVO CY - Rockville, Md. ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Vilser, W. A1 - Schmidt-Trucksäss, A. A1 - Halle, M. A1 - Lanzl, I. M. T1 - Zeitliche Schwingungen retinaler Gefäßdurchmesser bei Gesunden unterschiedlichen Alters : Kreuz- und Autokorrelation für dynamische Gefäßanalyse JF - Der Ophthalmologe Y1 - 2009 SN - 1433-0423 VL - 106 IS - 7 SP - 609 EP - 618 PB - - ER - TY - JOUR A1 - Lanzl, Ines M. A1 - Seidova, Seid-Fatima A1 - Maier, Mathias A1 - Schmidt-Trucksäss, Arno A1 - Halle, Martin A1 - Kotliar, Konstantin T1 - Dynamic retinal vessel response to flicker in age-related macular degeneration patients before and after vascular endothelial growth factor inhibitor injection JF - Acta Ophthalmologica Y1 - 2011 SN - 1755-3768 VL - 89 IS - 5 SP - 472 EP - 479 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Maier, Mathias A1 - Bauer, Svetlana A1 - Feucht, Nikolaus A1 - Lohmann, Chris A1 - Lanzl, Ines T1 - Intravitreal injection of triamcinolone acetonide and intraocular pressure: author's reply JF - Acta Ophthalmologica Y1 - 2008 SN - 1755-3768 VL - 86 IS - 6 SP - 692 EP - 693 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Nagel, Edgar A1 - Vilser, Walthard A1 - Lanzl, Ines M. T1 - Functional in vivo assessment of retinal artery microirregularities in glaucoma / Kotliar, Konstantin E. ; Nagel, Edgar ; Vilser, Walthard ; Lanzl, Ines M. JF - Acta Ophthalmologica. 86 (2008), H. 4 Y1 - 2008 SN - 1755-3768 SP - 424 EP - 433 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Maier, Mathias A1 - Bauer, Svetlana A1 - Feucht, Nikolaus T1 - Effect of intravitreal injections and volume changes on intraocular pressure: clinical results and biomechanical model / Kotliar, Konstantin ; Maier, Mathias ; Bauer, Svetlana ; Feucht, Nikolaus ; Lohmann, Chris ; Lanzl, Ines JF - Acta Ophthalmologica Scandinavica. 85 (2007), H. 7 Y1 - 2007 SN - 1755-3768 SP - 777 EP - 781 PB - - ER - TY - JOUR A1 - Nurispahic, A. A1 - Kotliar, Konstantin A1 - Lanzl, I. T1 - Messung der Akkommodation mittels optischer Biometrie JF - Der Ophthalmologe Y1 - 2008 SN - 1433-0423 VL - 105 IS - 4 SP - 369 EP - 375 PB - - ER - TY - JOUR A1 - Lanzl, Ines M. A1 - Seidova, Seid-Fatima A1 - Erben, A. A1 - Thürmel, K. A1 - Kotliar, Konstantin T1 - Diffuse stromale Hornhauttrübungen und Veränderungen der Hände JF - Der Ophthalmologe N2 - Bilaterale stromale Hornhauttrübungen sind für den Augenarzt eine differenzialdiagnostische Herausforderung. Im folgenden Beitrag werden 2 Patieninnen (30 und 36 Jahre) mit unterschiedlich stark ausgeprägter stromaler diffuser Hornhauttrübung vorgestellt. Patientin 1 war kleinwüchsig (114 cm) und Patientin 2 normal groß (172 cm). Beide Patientinnen wiesen veränderte Gelenkstrukturen an Hand und Fußgelenken sowie diffuse stromale Hornhauttrübungen auf. Des Weiteren lagen eine Mitral- und Aorteninsuffizienz (Patientin 1) bzw. eine Aorteninsuffizienz (Patientin 2) vor. Die stromalen diffusen Hornhauttrübungen ließen im Zusammenhang mit den Gelenkveränderungen ein Scheie-Syndrom vermuten. Therapeutisch ist bei Patienten mit Visusminderung eine (lamelläre) Keratoplastik sinnvoll. Y1 - 2010 U6 - https://doi.org/10.1007/s00347-009-2066-2 SN - 1433-0423 VL - 107 IS - 4 SP - 363 EP - 365 PB - Springer CY - Berlin ER - TY - JOUR A1 - Wiescher, A. A1 - Kotliar, Konstantin A1 - Neuhann, T. A1 - Lanzl, Ines M. T1 - Rasch progrediente Visusminderung beider Augen bei einem jungen Patienten JF - Der Ophthalmologe N2 - Ein 34-jähriger männlicher Patient stellte sich zur Abklärung einer seit dem 9. Lebensjahr bestehenden und im letzten Jahr rasch progredienten Visusminderung beider Augen bei uns vor. Er beschrieb eine subjektiv zunehmende, im Spiegel für ihn selbst sichtbare, weißliche Trübung in der Pupille beidseits und eine starke Blendempfindlichkeit. Nebenbefundlich gab er rezidivierende Konjunktivitiden und morgens verklebte Lider an. Eine Allergie auf Gräserpollen und eine Unverträglichkeit auf Alkohol sowie mehrere Lebensmittel seien ebenfalls bekannt. Zusätzlich leidet der Patient an stark ausgeprägtem atopischem Ekzem. Dieses wurde nie systemisch, sondern nur bei Bedarf mit kortisonhaltiger Salbe therapiert. Y1 - 2010 U6 - https://doi.org/10.1007/s00347-007-1586-x SN - 1433-0423 VL - 105 IS - 4 SP - 389 EP - 392 PB - Springer CY - Berlin ER - TY - JOUR A1 - Menzel, C. A1 - Kotliar, Konstantin A1 - Lanzl, I. T1 - Retrospektive Untersuchung jahreszeitlich bedingter Einflussfaktoren auf den Augeninnendruck therapierter Glaukompatienten JF - Der Ophthalmologe Y1 - 2009 SN - 1433-0423 VL - 106 IS - 11 SP - 1006 EP - 1011 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Mogilevskiĭ, A. Ia. A1 - Shilo, A. V. A1 - Panchekha, A. P. T1 - [Chaotic non-linear dynamics of alpha-band of the EEg and organization of the cortical activity of P300 wave] / Mogilevskiĭ, A. Ia. ; Kotliar, K. E. ; Shilo, A. V. ; Panchekha, A. P. JF - Zhurnal vyssheĭ nervnoĭ deiatelnosti imeni I P Pavlova. 58 (2008), H. 5 Y1 - 2008 SN - 0044-4677 N1 - Original in Russisch ; English abstract SP - 562 EP - 575 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Svetlova, O. V. A1 - Makarov, F. N. A1 - Zaseeva, M. V. T1 - Morfologicheskie i funktsional'nye osobennosti resnichnogo poiaska khrustalika kak kliuchevogo ispolnitel'nogo zvena v mekhanizme akkommodatsii glaza cheloveka = Morpho-functional characteristics of lens ciliary body as a key mechanism of accommodation in JF - Morfologiia (Saint Petersburg, Russia). 123 (2003), H. 3 Y1 - 2003 SN - 1026-3543 N1 - Original in Russisch, English abstract SP - 7 EP - 16 PB - - ER - TY - JOUR A1 - Maier, M. M. A1 - Feucht, N. A1 - Winkler von Mohrenfels, C. A1 - Kotliar, Konstantin A1 - Fabian, E. A1 - Lohmann, C. P. T1 - Nahtlose Cerclage mit Skleratunnelfixation. Sutureless Encircling Band - Clinical Experience JF - Klinische Monatsblätter für Augenheilkunde Y1 - 2011 SN - 0344-6360 VL - 228 IS - 5 SP - 473 EP - 476 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Pressler, Axel A1 - Esefeld, Katrin A1 - Scherr, Johannes A1 - Ali, Mohammad A1 - Hanssen, Henner A1 - Kotliar, Konstantin A1 - Lanzl, Ines A1 - Halle, Martin A1 - Kaemmerer, Harald A1 - Schmidt-Trucksäss, Arno A1 - Hager, Alfred T1 - Structural alterations of retinal arterioles in adults late after repair of aortic isthmic coarctation JF - The American Journal of Cardiology N2 - Patients after coarctation repair still have an increased risk of cardiovascular or cerebrovascular events. This has been explained by the persisting hypertension and alterations in the peripheral vessels. However, involvement of the central vessels such as the retinal arteries is virtually unknown. A total of 34 patients after coarctation repair (22 men and 12 women; 23 to 58 years old, age range 0 to 32 years at surgical repair) and 34 nonhypertensive controls underwent structural and functional retinal vessel analysis. Using structural analysis, the vessel diameters were measured. Using functional analysis, the endothelium-dependent vessel dilation in response to flicker light stimulation was assessed. In the patients after coarctation repair, the retinal arteriolar diameter was significantly reduced compared to that of the controls (median 182 μm, first to third quartile 171 to 197; vs 197 μm, first to third quartile 193 to 206; p <0.001). These findings were independent of the peripheral blood pressure and age at intervention. No differences were found for venules. The functional analysis findings were not different between the patients and controls (maximum dilation 3.5%, first to third quartile 2.1% to 4.5% vs 3.6%, first to third quartile 2.2% to 4.3%; p = 0.81), indicating preserved autoregulative mechanisms. In conclusion, the retinal artery diameter is reduced in patients after coarctation repair, independent of their current blood pressure level and age at intervention. As a structural marker of chronic vessel damage associated with past, current, or future hypertension, retinal arteriolar narrowing has been linked to stroke incidence. These results indicate an involvement of cerebral microcirculation in aortic coarctation, despite timely repair, and might contribute to explain the increased rate of cerebrovascular events in such patients. Y1 - 2010 U6 - https://doi.org/10.1016/j.amjcard.2009.10.070 SN - 0002-9149 VL - 105 IS - 5 SP - 740 EP - 744 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Mikielewicz, Marek A1 - Kotliar, Konstantin A1 - Barraquer, Rafael I. A1 - Michael, Ralph T1 - Air-pulse corneal applanation signal curve parameters for the characterisation of keratoconus JF - British Journal of Ophthalmology (eBJO) Y1 - 2011 SN - 1468-2079 VL - 95 IS - 6 SP - 793 EP - 798 PB - BMJ Publ. Group CY - London ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Baumann, Marcus A1 - Vilser, Walthard A1 - Lanzl, Ines M. T1 - Pulse wave velocity in retinal arteries of healthy volunteers JF - British Journal of Ophthalmology (eBJO) Y1 - 2011 SN - 1468-2079 VL - 95 IS - 11 SP - 675 EP - 679 PB - BMJ Publ. Group CY - London ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Schmidt-Trucksäss, A. A1 - Sitnikova, Diana A1 - Ali, Mohammad A1 - Blume, Katharina A1 - Halle, Martin A1 - Hansser, Henner T1 - Dynamic retinal vessel response to flicker in obesity: A methodological approach JF - Microvascular Research Y1 - 2011 SN - 0026-2862 VL - 81 IS - 1 SP - 123 EP - 128 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dashevsky, Alexey V. A1 - Lanzl, Ines M. A1 - Kotliar, Konstantin T1 - Non-penetrating intracanalicular partial trabeculectomy via the ostia of Schlemm's canal JF - Graefe's Archive for Clinical and Experimental Ophthalmology Y1 - 2011 SN - 0721-832x VL - 249 IS - 4 SP - 565 EP - 573 PB - Springer CY - Berlin ER - TY - JOUR A1 - Baumann, Marcus A1 - Schwarz, Sonja A1 - Kotliar, Konstantin A1 - Eynatten, Maximilian von A1 - Trucksaess, Arno A1 - Burckhardt, Klaus A1 - Lutz, Jens A1 - Heemann, Uwe A1 - Lanzl, Ines T1 - Non-diabetic chronic kidney disease influences retinal microvasculature JF - Kidney and Blood Pressure Research Y1 - 2009 SN - 1423-0143 VL - 32 IS - 6 SP - 428 EP - 433 PB - - ER - TY - JOUR A1 - Hanssen, H. A1 - Nickel, T. A1 - Drexel, V. A1 - Hertel, G. A1 - Emslander, I. A1 - Sisic, Z. A1 - Lorang, D. A1 - Schuster, T. A1 - Kotliar, Konstantin A1 - Pressler, A. A1 - Schmidt-Trucksäss, A. A1 - Weis, M. A1 - Halle, M. T1 - Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity JF - Atherosclerosis Y1 - 2011 SN - 0021-9150 VL - 216 IS - 2 SP - 433 EP - 439 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Burkhardt, Klaus A1 - Schwarz, Sonja A1 - Pan, Chengrui A1 - Stelter, Felix A1 - Kotliar, Konstantin A1 - Eynatten, Maxilian von A1 - Sollinger, Daniel A1 - Lanzl, Ines A1 - Heemann, Uwe A1 - Baumann, Marcus T1 - Myeloid-related protein 8/14 complex describes microcirculatory alterations in patients with type 2 diabetes and nephropathy JF - Cardiovascular Diabetology Y1 - 2009 SN - 1475-2840 VL - 8 IS - 10 SP - 1 EP - 8 PB - - ER - TY - JOUR A1 - Garhofer, Gerhard A1 - Bek, Toke A1 - Boehm, Andreas G. A1 - Gherghel, Doina A1 - Grundwald, Juan A1 - Jeppesen, Peter A1 - Kergoat, Hélène A1 - Kotliar, Konstantin A1 - Lanzl, Ines A1 - Lovasik, John V. A1 - Nagel, Edgar A1 - Vilser, Walthard A1 - Orgul, Selim A1 - Schmetterer, Leopold T1 - Use of the retinal vessel analyzer in ocular blood flow research JF - Acta Ophthalmol N2 - The present article describes a standard instrument for the continuous online determination of retinal vessel diameters, the commercially available retinal vessel analyzer. This report is intended to provide informed guidelines for measuring ocular blood flow with this system. The report describes the principles underlying the method and the instruments currently available, and discusses clinical protocol and the specific parameters measured by the system. Unresolved questions and the possible limitations of the technique are also discussed. Y1 - 2010 U6 - https://doi.org/10.1111/j.1755-3768.2009.01587.x SN - 1755-3768 VL - 88 IS - 7 SP - 717 EP - 722 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Kozlova, Tatiana V. A1 - Lanzl, Ines M. T1 - Postoperative aqueous outflow in the human eye after glaucoma filtration surgery: biofluidmechanical considerations JF - Biomedizinische Technik = Biomedical Engineering Y1 - 2009 SN - 1862-278X VL - 54 IS - 1 SP - 14 EP - 22 PB - - ER - TY - JOUR A1 - Seidova, Seid-Fatima A1 - Kotliar, Konstantin A1 - Foerger, Frauke A1 - Klopfer, Matthias A1 - Lanzl, Ines T1 - Functional retinal changes in Gaucher disease JF - Documenta Ophthalmologica Y1 - 2009 SN - 1573-2622 VL - 118 IS - 2 SP - 151 EP - 154 PB - Springer CY - Berlin ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Lanzl, Ines M. A1 - Maier, Mathias A1 - Feucht, Nikolaus T1 - Intraocular pressure effects of pegaptanib (macugen) injections in patients with and without glaucoma / Lanzl, Ines M. ; Maier, Mathias ; Feucht, Nikolaus ; Lohmann, Chris P. ; Kotliar, Konstantin E. JF - American Journal of Ophthalmology . 145 (2008), H. 1 Y1 - 2008 SN - 1879-1891 SP - 185 EP - 185 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Vilser, Walthatd A1 - Nagel, Edgar A1 - Lanzl, Ines M. T1 - Retinal vessel reaction in response to chromatic flickering light / Kotliar, Konstantin E. ; Vilser, Walthard ; Nagel, Edgar ; Lanzl, Ines M. JF - Graefe's Archive for Clinical and Experimental Ophthalmology. 242 (2004), H. 5 Y1 - 2004 SN - 1435-702X SP - 377 EP - 392 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Bauer, S. M. A1 - Zamuraev, L. A. T1 - Model of the transversely isotropic spherical layer for estimation of intraocular pressure changes after intravitreal injections / Bauer, S. M. ; Zamuraev, L. A. ; Kotliar, K. E. JF - Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 10 (2006), H. 2 Y1 - 2006 SN - 1812-5123 SP - 41 EP - 47 PB - - ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Koshitz, I. N. A1 - Svetlova, O. V. A1 - Zaseeva, M. V. T1 - Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part I Initial theoretical presuppositions, hypotheses and facts / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotli JF - Glaukoma (2006) Y1 - 2006 N1 - Original in Russisch SP - 35 EP - 53 PB - - ER - TY - JOUR A1 - Maggakis-Kelemen, C. A1 - Bork, M. A1 - Kayser, Peter A1 - Biselli, Manfred A1 - Artmann, Gerhard T1 - Biological and mechanical quality of red blood cells cultured from human umbilical cord blood stem cells JF - Medical and biological engineering and computing. 41 (2003), H. 3 Y1 - 2003 SN - 0140-0118 SP - 350 EP - 356 ER - TY - JOUR A1 - Tran, Thanh Ngoc A1 - Pham, Phu Tinh A1 - Vu, D. K. A1 - Staat, Manfred T1 - Reliability Analysis of Inelastic Shell Structures Under Variable Loads JF - Limit States of Materials and Structures : Direct Methods / Hrsg. Dieter Weichert; Hrsg. Alan Ponter Y1 - 2009 SN - 978-1-4020-9633-4 SP - 135 EP - 156 PB - Springer Netherland CY - Berlin ER - TY - JOUR A1 - Artmann, Gerhard A1 - Digel, Ilya A1 - Zerlin, Kay A1 - Maggakis-Kelemen, Christina A1 - Linder, Peter A1 - Porst, Dariusz A1 - Kayser, Peter A1 - Stadler, David A1 - Dikta, Gerhard A1 - Temiz Artmann, Aysegül T1 - Hemoglobin senses body temperature JF - European Biophysics Journal Y1 - 2009 SN - 0175-7571 VL - 38 IS - 5 SP - 589 EP - 600 ER - TY - JOUR A1 - Kaul, D. K. A1 - Koshkaryev, A. A1 - Artmann, Gerhard A1 - Barshtein, G. A1 - Yedgar, S. T1 - Additive effect of red blood cell rigidity and adherence to endothelial cells in inducing vascular resistance JF - American Journal of Physiology : Heart and Circulation Physiology . 295 (2008), H. 4 Y1 - 2008 SN - 1522-1539 VL - 295 IS - 4 SP - H1788 EP - H1793 ER - TY - JOUR A1 - Stadler, A. M. A1 - Digel, Ilya A1 - Artmann, Gerhard A1 - Embs, Jan P. A1 - Zaccai, Joe A1 - Büldt, Georg T1 - Hemoglobin Dynamics in Red Blood Cells: Correlation to Body Temperature JF - Biophysical Journal. 95 (2008), H. 11 Y1 - 2008 SN - 1542-0086 SP - 5449 EP - 5461 ER - TY - JOUR A1 - Eschweiler, J. A1 - Laack, Walter van A1 - Staat, Manfred T1 - Elektromyographische Untersuchungen zur Kräftigung der Oberschenkelmuskulatur mit einem myoelektrischen Stimulator nach arthroskopischen Eingriffen am Kniegelenk JF - Orthopädische Praxis. 43 (2007), H. 10 Y1 - 2007 SN - 0030-588x SP - 539 EP - 542 ER - TY - JOUR A1 - Scholz, A. A1 - Ley, Wilfried A1 - Dachwald, Bernd A1 - Miau, J. J. A1 - Juang, J. C. T1 - Flight results of the COMPASS-1 picosatellite mission JF - Acta Astronautica. 67 (2010), H. 9-10 Y1 - 2010 SN - 0094-5765 SP - 1289 EP - 1298 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, Wolfgang T1 - Solar sailcraft of the first generation mission applications to near-earth asteroids Y1 - 2003 N1 - 54th International Astronautical Congress of the International Astronautical Federation, the International Academy of Astronautics, and the International Institute of Space Law 29 September - 3 October 2003, Bremen, Germany IAC-03-Q.5.06 ER - TY - JOUR A1 - Dachwald, Bernd A1 - Seboldt, Wolfgang T1 - Solar sailcraft of the first generation technology development / Seboldt, Wolfgang ; Dachwald, Bernd Y1 - 2003 N1 - 54th International Astronautical Congress of the International Astronautical Federation, the International Academy of Astronautics, and the International Institute of Space Law 29 September - 3 October 2003, Bremen, Germany IAC-03-S.03 ER - TY - JOUR A1 - Linden, A. A1 - Fischöder, M. A1 - Laack, Walter van A1 - Staat, Manfred T1 - Einschränkung von Taluskippung und -vorschub durch Sprunggelenkorthesen nach fibularer Bandruptur JF - OUP Zeitschrift für die orthopädische und unfallchirurgische Praxis N2 - Die fibulare Bandruptur zählt zu einer der am häufigsten auftretenden Verletzungen des Bewegungsapparats. In den meisten Fällen wird heute die konservativ frühfunktionelle Therapie mit Sprunggelenkorthesen allgemein bevorzugt. Im Rahmen der vorliegenden Studie wurden 14 verschiedene Sprunggelenkorthesen im Hinblick auf ihre Einschränkung von Taluskippung und Talusvorschub untersucht. Zur Simulation einer fibularen Bandruptur wurde ein Unterschenkelmodell aus Holz mit Fußteil, mit angelegten Orthesen in einen Scheuba-Halteapparat eingespannt und mit 150 N seitlich sowie anterior-posterior belastet. Anhand der erstellten "gehaltenen" Röntgenaufnahmen konnten Taluskippung und Talusvorschub jeder einzelnen Orthese eindeutig bestimmt werden. Die meisten Orthesen erreichten zufriedenstellende Ergebnisse. Es stellte sich heraus, dass vor allem eine eng anliegende, im Gelenkbereich anatomisch angepasste Form vorteilhaft zu sein scheint. N2 - The ankle sprain is actually one of the most common injuries. Nowadays the conservative pre-functional therapy with ankle braces is generally preferred. In the present study 14 different ankle braces were tested with regard to their ability to constrict the talar tilt and anterior drawer displacement. As part of the tests a wooden model of a foot was used in order to simulate an ankle sprain. This model was clamped in a Scheuba-device with different ankle braces and a force of 150 N was applied to it. The stress radiographs showed different talar tilts and anterior drawers of each brace. Most ankle braces achieved a satisfying result. It has become obvious that a tight fitting and an anatomically designed shape seem to be favourable. T2 - Constraint of talar tilt and anterior drawer by different ankle braces after the rupture of fibular ligaments KW - Sprunggelenkorthesen KW - fibulare Bandruptur KW - Distorsion des oberen Sprunggelenks KW - ankle sprain KW - rupture of the fibular ligament KW - ankle braces Y1 - 2013 SN - 2193-5785 U6 - https://doi.org/10.3238/oup.2013.0306-0309 VL - 2 IS - 6 SP - 306 EP - 309 PB - Deutscher Ärzte-Verl. CY - Köln ER - TY - JOUR A1 - Staat, Manfred T1 - Limit and shakedown analysis under uncertainty JF - International journal of computational methods : IJCM Y1 - 2013 SN - 0219-8762 SP - Publ. online PB - World Scientific Publishing CY - Singapore ER - TY - CHAP A1 - Frotscher, Ralf A1 - Goßmann, Matthias A1 - Temiz Artmann, Aysegül A1 - Staat, Manfred T1 - Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM T2 - 1st International Conference "Shell and Membrane Theories in Mechanics and Biology: From Macro- to Nanoscale Structures", Minsk, Belarus, Sept. 16-20, 2013 Y1 - 2013 SN - 978-985-553-135-8 SP - 165 EP - 167 PB - Verl. d. Weißruss. Staatl. Univ. CY - Minsk ER - TY - CHAP A1 - Tran, Thanh Ngoc A1 - Staat, Manfred T1 - Shakedown analysis of Reissner-Mindlin plates using the edge-based smoothed finite element method T2 - Direct methods for limit states in structures and materials / Dieter Weichert ; Alan Ponter, ed. N2 - This paper concerns the development of a primal-dual algorithm for limit and shakedown analysis of Reissner-Mindlin plates made of von Mises material. At each optimization iteration, the lower bound of the shakedown load multiplier is calculated simultaneously with the upper bound using the duality theory. An edge-based smoothed finite element method (ES-FEM) combined with the discrete shear gap (DSG) technique is used to improve the accuracy of the solutions and to avoid the transverse shear locking behaviour. The method not only possesses all inherent features of convergence and accuracy from ES-FEM, but also ensures that the total number of variables in the optimization problem is kept to a minimum compared with the standard finite element formulation. Numerical examples are presented to demonstrate the effectiveness of the present method. Y1 - 2014 SN - 978-94-007-6826-0 (Print) 978-94-007-6827-7 (Online) U6 - https://doi.org/10.1007/978-94-007-6827-7_5 SP - 101 EP - 117 PB - Springer CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram T1 - Flight style optimization in ski jumping on normal, large, and ski flying hills JF - Journal of biomechanics Y1 - 2013 SN - 1873-2380 (E-Journal); 0021-9290 (Print) N1 - Corrigendum to “Flight style optimization in ski jumping on normal, large, and ski flying hills” [J. Biomech 47 (2014) 716-722] Journal of Biomechanics, 2018;71:313. VL - Vol. 47 IS - Iss. 3 SP - 716 EP - 722 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Kotliar, Konstantin T1 - Pathophysiologische Beurteilung und hämodynamische Analyse von mikrostrukturellen Veränderungen des retinalen Gefäßlängsschnittsprofils Y1 - 2012 N1 - Moskau, Habil.-Schr. ,Russ. Univ., Med. Fakultät, 2012. Originaltitel in Russisch. ER - TY - CHAP A1 - Lanzl, I. A1 - Seidova, S.-F. A1 - Dühring, C. von A1 - Kotliar, Konstantin ED - Erb, Carl T1 - Befunde der dynamischen Gefäßanalyse am Auge bei Gesunden und Glaukom-Patienten mit praxisrelevanter Bedeutung T2 - Mikrozirkulation beim Glaukom Y1 - 2009 N1 - Search on Glaucoma SP - 33 EP - 39 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Krämer, Stefan A1 - Daab, Dominique Jonas A1 - Müller, Brigitte A1 - Wagner, Tobias A1 - Baader, Fabian A1 - Hessel, Joana A1 - Gdalewitsch, Georg A1 - Plescher, Engelbert A1 - Dachwald, Bernd A1 - Wahle, Michael A1 - Gierse, Andreas A1 - Vetter, Rudolf A1 - Pfützenreuter, Lysan T1 - Development and flight-testing of a system to isolate vibrations for microgravity experiments on sounding rockets JF - 21st ESA Symposium on Rocket and Balloon Research Y1 - 2013 SP - 1 EP - 8 ER - TY - JOUR A1 - Jiminez German, Salvador A1 - Behbahani, Mehdi A1 - Miettinen, Susanna A1 - Grijpma, Dirk W. A1 - Haimi, Suvi P. T1 - Proliferation and differentiation of adipose stem cells towards smooth muscle cells on poly(trimethylene carbonate) membranes JF - Macromolecular symposia Y1 - 2013 SN - 0258-0322 VL - Vol. 334 IS - Iss. 1 SP - 133 EP - 142 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Pham, Phu Tinh A1 - Staat, Manfred T1 - FEM-based shakedown analysis of hardening structures JF - Asia Pacific journal on computational engineering N2 - This paper develops a new finite element method (FEM)-based upper bound algorithm for limit and shakedown analysis of hardening structures by a direct plasticity method. The hardening model is a simple two-surface model of plasticity with a fixed bounding surface. The initial yield surface can translate inside the bounding surface, and it is bounded by one of the two equivalent conditions: (1) it always stays inside the bounding surface or (2) its centre cannot move outside the back-stress surface. The algorithm gives an effective tool to analyze the problems with a very high number of degree of freedom. Our numerical results are very close to the analytical solutions and numerical solutions in literature. Y1 - 2014 U6 - https://doi.org/10.1186/2196-1166-1-4 SN - 2196-1166 (E-Journal) IS - 1 SP - Article No. 4 PB - SpringerOpen CY - Berlin ER - TY - JOUR A1 - Fuest, Matthias A1 - Kotliar, Konstantin A1 - Walter, Peter A1 - Plange, Niklas T1 - Monitoring intraocular pressure changes after intravitreal Ranibizumab injection using rebound tonometry JF - Ophthalmic and physiological optics Y1 - 2014 U6 - https://doi.org/10.1111/opo.12134 SN - 1475-1313 (E-Journal); 0275-5408 (Print) N1 - Special Issue: The Ageing Visual System VL - 34 IS - 4 SP - 438 EP - 444 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Turaliyeva, M. A1 - Yeshibaev, A. A1 - Digel, Ilya A1 - Elibayeva, G. A1 - Sydykova, A. A1 - Uspabayeva, A. A1 - Dosybayeva, G. A1 - Zhylysbayeva, A. A1 - Lakhanova, K. T1 - Molecular-genetic identification of emerged novel invasive pathogens of Asiatic Elm Ulmus pumila L JF - Life science journal N2 - The dwarf elm Ulmus pumila L. (Ulmaceae) is one of indigenous species of flora in Kazakhstan and forms a basis of dendroflora in virtually all settlements of the region. In the past decade, multiple outbreaks of previously unknown diseases of the small-leaved elm have been registered. In our study, by the molecular-genetic analysis it was found that the pathogens responsible for the outbreaks are microfungi belonging to the genus Fusarium – F. solani and F. oxysporum. The nucleotide sequences (ITS regions) isolated from the diseased trees showed very high similarity with the GenBank control numbers EU625403.1 and FJ478128.1 (100.0 and 99.0 % respectively). Oncoming research will focus on the search of natural microbial antagonists of the discovered phytopathogens. Y1 - 2014 U6 - https://doi.org/10.7537/marslsj1105s14.33 SN - 1097-8135 VL - 11 IS - Spec. iss. 5s SP - 171 EP - 175 PB - Marsland Press CY - New York ER - TY - JOUR A1 - Mansurov, Z. A. A1 - Jandosov, J. M. A1 - Kerimkulova, A. R. A1 - Azat, S. A1 - Zhubanova, A. A. A1 - Digel, Ilya A1 - Savistkaya, I. S. A1 - Akimbekov, Nuraly S. A1 - Kistaubaeva, A. S. T1 - Nanostructured carbon materials for biomedical use JF - Eurasian chemico-technological journal : quarterly journal of the International Higher Education Academy of Sciences N2 - One of the priority trends of carbon nanotechnology is creation of nanocomposite systems. Such carbon nanostructured composites were produced using - raw materials based on the products of agricultural waste, such as grape stones, apricot stones, rice husk. These products have a - wide spectrum of application and can be obtained in large quantities. The Institute of Combustion Problems has carried out the work on synthesis of the nanostructured carbon sorbents for multiple applications including the field of biomedicine. The article presents the data on the synthesis and physico-chemical properties of carbonaceous sorbents using physicochemical methods of investigation: separation and purification of biomolecules; isolation of phytohormone - fusicoccin; adsorbent INGO-1 in the form of an adsorption column for blood detoxification, oral (entero) sorbent - INGO-2; the study of efferent and probiotic properties and sorption activity in regard to the lipopolysaccharide (LPS), new biocomposites - based on carbonized rice husk (CRH) and cellular microorganisms; the use of CRH in wound treatment. A new material for blood detoxication (INGO-1) has been obtained. Adsorption of p-cresyl sulfate and indoxyl sulfate has shown that active carbon adsorbent can remove clinically significant level of p-cresyl sulfate and indoxyl sulfate from human plasma. Enterosorbent INGO-2 possesses high adsorption activity in relation to Gram-negative bacteria and their endotoxins. INGO-2 slows down the growth of conditionally pathogenic microorganisms, without having a negative effect on bifido and lactobacteria. The use of enterosorbent INGO-2 for sorption therapy may provide a solution to a complex problem - detoxication of the digestive tract and normalization of the intestinal micro ecology. The immobilized probiotic called "Riso-lact" was registered at the Ministry of Health of the Republic of Kazakhstan as a biologically active food additive. The developed technology is patented and provides production of the medicine in the form of freeze-dried biomass immobilized in vials. Y1 - 2014 U6 - https://doi.org/10.18321/ectj224 SN - 1562-3920 VL - 15 (2013) IS - 3 SP - 209 EP - 217 PB - Institute of Combustion Problems CY - Almaty ER - TY - JOUR A1 - Ciobanu, Octavian A1 - Staat, Manfred A1 - Rahimi, Alireza T1 - The use of open source software in biomechanical finite element analysis JF - Buletinul Institutului Politehnic din Iaşi / Universitatea Tehnică Gh. Asachi, Iaşi Secţia 5, Construcţii de maşini = Machine construction = Bulletin of the Polytechnic Institute of Jassy = Izvestija Jasskogo Politechničeskogo Instituta Y1 - 2008 SN - 1011-2855 VL - 54 IS - 7/8 SP - 213 EP - 220 ER - TY - JOUR A1 - Cehreli, Ruksan A1 - Akpinar, Hale A1 - Temiz Artmann, Aysegül A1 - Sagol, Ozgul T1 - Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis JF - Gastroenterology Research Y1 - 2015 U6 - https://doi.org/10.14740/gr683w SN - 1918-2813 VL - 8 IS - 5 SP - 265 EP - 273 ER - TY - CHAP A1 - Peloni, Alessandro A1 - Ceriotti, Matteo A1 - Dachwald, Bernd T1 - Solar-Sailing Trajectory Design for Close-up NEA Observations Mission T2 - 4th IAA Planetary Defense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy Y1 - 2015 N1 - IAA-PDC-15-P-19 ER - TY - JOUR A1 - Duong, Minh Tuan A1 - Nguyen, Nhu Huynh A1 - Staat, Manfred T1 - Physical response of hyperelastic models for composite materials and soft tissues JF - Asia pacific journal on computational engineering Y1 - 2015 U6 - https://doi.org/10.1186/s40540-015-0015-x SN - 2196-1166 VL - 2 IS - 3 (December 2015) SP - 1 EP - 18 ER - TY - JOUR A1 - Frotscher, Ralf A1 - Muanghong, Danita A1 - Dursun, Gözde A1 - Goßmann, Matthias A1 - Temiz Artmann, Aysegül A1 - Staat, Manfred T1 - Sample-specific adaption of an improved electro-mechanical model of in vitro cardiac tissue JF - Journal of Biomechanics N2 - We present an electromechanically coupled computational model for the investigation of a thin cardiac tissue construct consisting of human-induced pluripotent stem cell-derived atrial, ventricular and sinoatrial cardiomyocytes. The mechanical and electrophysiological parts of the finite element model, as well as their coupling are explained in detail. The model is implemented in the open source finite element code Code_Aster and is employed for the simulation of a thin circular membrane deflected by a monolayer of autonomously beating, circular, thin cardiac tissue. Two cardio-active drugs, S-Bay K8644 and veratridine, are applied in experiments and simulations and are investigated with respect to their chronotropic effects on the tissue. These results demonstrate the potential of coupled micro- and macroscopic electromechanical models of cardiac tissue to be adapted to experimental results at the cellular level. Further model improvements are discussed taking into account experimentally measurable quantities that can easily be extracted from the obtained experimental results. The goal is to estimate the potential to adapt the presented model to sample specific cell cultures. KW - hiPS cardiomyocytes KW - Homogenization KW - Hodgkin–Huxley models KW - Frequency adaption KW - Electromechanical modeling KW - Drug simulation KW - Computational biomechanics KW - Cardiac tissue Y1 - 2016 U6 - https://doi.org/10.1016/j.jbiomech.2016.01.039 SN - 0021-9290 (Print) SN - 1873-2380 (Online) VL - 49 IS - 12 SP - 2428 EP - 2435 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram T1 - Effect of wind on flight style optimisation in ski jumping T2 - 15th International Symposium on Computer Simulation in Biomechanics ; July 9th-11th 2015, Edinburgh, UK Y1 - 2016 SP - 53 EP - 54 PB - The University of Edinburgh ; Loughborough University CY - Edinburgh ER - TY - CHAP A1 - Dachwald, Bernd A1 - Boehnhardt, Herrmann A1 - Broj, Ulrich A1 - Geppert, Ulrich R. M. E. A1 - Grundmann, Jan-Thimo A1 - Seboldt, Wolfgang A1 - Seefeldt, Patric A1 - Spietz, Peter A1 - Johnson, Les A1 - Kührt, Ekkehard A1 - Mottola, Stefano A1 - Macdonald, Malcolm A1 - McInnes, Colin R. A1 - Vasile, Massimiliano A1 - Reinhard, Ruedeger T1 - Gossamer roadmap technology reference study for a multiple NEO Rendezvous Mission T2 - Advances in solar sailing N2 - A technology reference study for a multiple near-Earth object (NEO) rendezvous mission with solar sailcraft is currently carried out by the authors of this paper. The investigated mission builds on previous concepts, but adopts a strong micro-spacecraft philosophy based on the DLR/ESA Gossamer technology. The main scientific objective of the mission is to explore the diversity of NEOs. After direct interplanetary insertion, the solar sailcraft should—within less than 10 years—rendezvous three NEOs that are not only scientifically interesting, but also from the point of human spaceight and planetary defense. In this paper, the objectives of the study are outlined and a preliminary potential mission profile is presented. Y1 - 2014 SN - 978-3-642-34906-5 (Print) ; 978-3-642-34907-2 (E-Book) SP - 211 EP - 226 PB - Springer CY - Berlin [u.a.] ER - TY - CHAP A1 - McInnes, Colin R. A1 - Bothmer, Volker A1 - Dachwald, Bernd A1 - Geppert, Ulrich R. M. E. A1 - Heiligers, Jeannette A1 - Hilgers, Alan A1 - Johnson, Les A1 - Macdonald, Malcolm A1 - Reinhard, Ruedeger A1 - Seboldt, Wolfgang A1 - Spietz, Peter T1 - Gossamer roadmap technology reference study for a Sub-L1 Space Weather Mission T2 - Advances in solar sailing N2 - A technology reference study for a displaced Lagrange point space weather mission is presented. The mission builds on previous concepts, but adopts a strong micro-spacecraft philosophy to deliver a low mass platform and payload which can be accommodated on the DLR/ESA Gossamer-3 technology demonstration mission. A direct escape from Geostationary Transfer Orbit is assumed with the sail deployed after the escape burn. The use of a miniaturized, low mass platform and payload then allows the Gossamer-3 solar sail to potentially double the warning time of space weather events. The mission profile and mass budgets will be presented to achieve these ambitious goals. Y1 - 2014 SN - 978-3-642-34906-5 (Print) ; 978-3-642-34907-2 (E-Book) SP - 227 EP - 242 PB - Springer CY - Berlin [u.a.] ER -