TY  - CHAP
A1  - Knott, Thomas C.
A1  - Sofronia, Raluca E.
A1  - Gerressen, Marcus
A1  - Law, Yuen
A1  - Davidescu, Arjana
A1  - Savii, George G.
A1  - Gatzweiler, Karl-Heinz
A1  - Staat, Manfred
A1  - Kuhlen, Torsten W.
T1  - Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy
T2  - Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)
N2  - Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted.
KW  - Bone sawing
KW  - virtual reality
KW  - training simulator
Y1  - 2014
SN  - 978-3-319-12057-7 (Online)
SN  - 978-3-319-12056-0 (Print)
U6  - http://dx.doi.org/10.1007/978-3-319-12057-7_1
SP  - 1
EP  - 10
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Konstantinidis, Konstantinos
A1  - Flores Martinez, Claudio
A1  - Dachwald, Bernd
A1  - Ohndorf, Andreas
A1  - Dykta, Paul
A1  - Bowitz, Pascal
A1  - Rudolph, Martin
A1  - Digel, Ilya
A1  - Kowalski, Julia
A1  - Voigt, Konstantin
A1  - Förstner, Roger
T1  - A lander mission to probe subglacial water on Saturn's moon enceladus for life
JF  - Acta astronautica
Y1  - 2015
SN  - 1879-2030 (E-Journal); 0094-5765 (Print)
VL  - Vol. 106
SP  - 63
EP  - 89
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Goßmann, Matthias
A1  - Raatschen, Hans-Jürgen
A1  - Temiz Artmann, Aysegül
A1  - Staat, Manfred
T1  - Simulation of cardiac cell-seeded membranes using the edge-based smoothed FEM
T2  - Shell and membrane theories in mechanics and biology. (Advanced structured materials ; 45)
N2  - We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.
Y1  - 2015
SN  - 978-3-319-02534-6 ; 978-3-319-02535-3
SP  - 187
EP  - 212
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - CHAP
A1  - Voronkova, Eva B.
A1  - Bauer, Svetlana M.
A1  - Kotliar, Konstantin
T1  - Computer simulation of the cornea-scleral shell as applied to pressure-volume relationship in the human eye
T2  - 2014 International Conference on Computer Technologies in Physical and Engineering Applications :  ICCTPEA 2014 : proceedings : June 30 2014-July 4 2014, St. Petersburg
Y1  - 2014
SN  - 978-1-4799-5315-8
SP  - 204
EP  - 205
ER  - 
TY  - JOUR
A1  - Dachwald, Bernd
A1  - Mikucki, Jill
A1  - Tulaczyk, Slawek
A1  - Digel, Ilya
A1  - Espe, Clemens
A1  - Feldmann, Marco
A1  - Francke, Gero
A1  - Kowalski, Julia
A1  - Xu, Changsheng
T1  - IceMole : A maneuverable probe for clean in situ analysis and sampling of subsurface ice and subglacial aquatic ecosystems
JF  - Annals of Glaciology
N2  - There is significant interest in sampling subglacial environments for geobiological studies, but they are difficult to access. Existing ice-drilling technologies make it cumbersome to maintain microbiologically clean access for sample acquisition and environmental stewardship of potentially fragile subglacial aquatic ecosystems. The IceMole is a maneuverable subsurface ice probe for clean in situ analysis and sampling of glacial ice and subglacial materials. The design is based on the novel concept of combining melting and mechanical propulsion. It can change melting direction by differential heating of the melting head and optional side-wall heaters. The first two prototypes were successfully tested between 2010 and 2012 on glaciers in Switzerland and Iceland. They demonstrated downward, horizontal and upward melting, as well as curve driving and dirt layer penetration. A more advanced probe is currently under development as part of the Enceladus Explorer (EnEx) project. It offers systems for obstacle avoidance, target detection, and navigation in ice. For the EnEx-IceMole, we will pay particular attention to clean protocols for the sampling of subglacial materials for biogeochemical analysis. We plan to use this probe for clean access into a unique subglacial aquatic environment at Blood Falls, Antarctica, with return of a subglacial brine sample.
KW  - Antarctic Glaciology
KW  - Extraterrestrial Glaciology
KW  - Glaciological instruments and methods
KW  - Subclacial exploration
KW  - Subglacial lakes
Y1  - 2014
U6  - http://dx.doi.org/10.3189/2014AoG65A004
SN  - 1727-5644
VL  - 55
IS  - 65
SP  - 14
EP  - 22
PB  - Cambridge University Press
CY  - Cambridge
ER  - 
TY  - CHAP
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - Uncertainty multimode failure and shakedown analysis of shells
T2  - Direct methods for limit and shakedown analysis of structures / eds. Paolo Fuschi ...
N2  - This paper presents a numerical procedure for reliability analysis of thin plates and shells with respect to plastic collapse or to inadaptation. The procedure involves a deterministic shakedown analysis for each probabilistic iteration, which is based on the upper bound approach and the use of the exact Ilyushin yield surface. Probabilistic shakedown analysis deals with uncertainties originated from the loads, material strength and thickness of the shell. Based on a direct definition of the limit state function, the calculation of the failure probability may be efficiently solved by using the First and Second Order Reliability Methods (FORM and SORM). The problem of reliability of structural systems (series systems) is handled by the application of a special technique which permits to find all the design points corresponding to all the failure modes. Studies show, in this case, that it improves considerably the FORM and SORM results.
KW  - Limit analysis
KW  - Shakedown analysis
KW  - Reliability analysis
KW  - Multimode failure
KW  - Non-linear optimization
Y1  - 2015
SN  - 978-3-319-12927-3 (print) ; 978-3-319-12928-0 (online)
U6  - http://dx.doi.org/10.1007/978-3-319-12928-0_14
SP  - 279
EP  - 298
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Seifarth, Volker
A1  - Goßmann, Matthias
A1  - Grosse, J. O.
A1  - Becker, C.
A1  - Heschel, I.
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Development of a Bioreactor to Culture Tissue Engineered Ureters Based on the Application of Tubular OPTIMAIX 3D Scaffolds
JF  - Urologia Internationalis
Y1  - 2015
U6  - http://dx.doi.org/10.1159/000368419
SN  - 0042-1138
VL  - 2015
IS  - 95
SP  - 106
EP  - 113
PB  - Karger
CY  - Basel
ER  - 
TY  - JOUR
A1  - Martin-Gonzalez, Anabel
A1  - Kotliar, Konstantin
A1  - Rios-Martinez, Jorge
A1  - Lanzl, Ines
A1  - Navab, Nassir
T1  - Mediated-reality magnification for macular degeneration rehabilitation
JF  - Journal of Modern Optics
Y1  - 2014
U6  - http://dx.doi.org/10.1080/09500340.2014.936110
SN  - 1362-3044
VL  - 61
IS  - 17
SP  - 1400
EP  - 1408
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment.
 Part I. Ocular blood circulation and its quantitative estimation
JF  - National journal Glaucoma
Y1  - 2006
SN  - 2078-4104
VL  - Vol. 5
IS  - No. 3
SP  - 62
EP  - 73
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Biomechanical modeling of the aqueous humor outflow after non-penetrating glaucoma filtration surgery in the human eye
JF  - Acta of bioengineering and biomechanics
Y1  - 2002
SN  - 1509-409X
VL  - Vol. 4
IS  - Suppl. 1
SP  - 728
EP  - 729
ER  - 
TY  - THES
A1  - Kotliar, Konstantin
T1  - Dynamische retinale Gefäßanalyse für die Diagnostik und Früherkennung von System- und Augenerkrankungen vaskulärer Genese
Y1  - 2013
N1  - München, Techn. Univ., Habil.-Schrift, 2013
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Kharoubi, A.
A1  - Schmidt-Trucksäß, A.
A1  - Halle, M.
A1  - Lanzl, I.
T1  - Does internal longitudinal microstructure of retinal veins change with age in medically healthy persons?
JF  - Acta Ophthalmologica
Y1  - 2009
SN  - 1600-0420 (E-Journal); 1755-3768 (E-Journal); 0001-639X (Print); 1395-3907 (Print); 1755-375X (Print)
VL  - Vol. 87
IS  - Suppl. S244
SP  - 0
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Kappmeyer, K.
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Spielen von Blasinstrumenten und Augeninnendruck
JF  - Zeitschrift für praktische Augenheilkunde & augenärztliche Fortbildung : ZPA
Y1  - 2009
SN  - 1436-0322
VL  - Bd. 30
SP  - 169
EP  - 171
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part III. Non-invasive methods of assessment of ocular blood flow. 2. Static and dynamic assessment of retinal vessel reaction to stimuli
JF  - National Journal Glaucoma
Y1  - 2007
SN  - 2078-4104
VL  - Vol. 6
IS  - No. 2
SP  - 64
EP  - 71
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part III. Non-invasive methods of assessment of ocular blood flow. 1. Assessment of blood cell velocities and flow rates in intraocular vessels and vascular beds
JF  - Journal of Glaucoma
Y1  - 2007
SN  - 2078-4104
VL  - Vol. 6
IS  - 1
SP  - 61
EP  - 68
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part II. Invasive methods of assessment of ocular blood flow
JF  - National Journal Glaucoma
Y1  - 2006
SN  - 2078-4104
VL  - Vol. 5
IS  - No. 4
SP  - 37
EP  - 49
ER  - 
TY  - JOUR
A1  - Frotscher, Ralf
A1  - Koch, Jan-Peter
A1  - Staat, Manfred
T1  - Computational investigation of drug action on human-induced stem cell derived cardiomyocytes
JF  - Journal of biomechanical engineering
Y1  - 2015
U6  - http://dx.doi.org/10.1115/1.4030173
SN  - 1528-8951 (E-Journal); 0148-0731 (Print)
VL  - Vol. 137
IS  - iss. 7
SP  - 071002-1
EP  - 071002-7
PB  - ASME
CY  - New York
ER  - 
TY  - JOUR
A1  - Duong, Minh Tuan
A1  - Nguyen, Nhu Huynh
A1  - Tran, Thanh Ngoc
A1  - Tolba, R. H.
A1  - Staat, Manfred
T1  - Influence of refrigerated storage on tensile mechanical properties of porcine liver and spleen
JF  - International biomechanics
Y1  - 2015
U6  - http://dx.doi.org/10.1080/23335432.2015.1049295
SN  - 2333-5432
VL  - Vol. 2
IS  - Iss. 1
SP  - 79
EP  - 88
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - CHAP
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - An electromechanical model for cardiac tissue constructs
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, 20.07.2015 - 23.07.2015  / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  - 
TY  - CHAP
A1  - Bhattarai, Aroj
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - Biomechanical study of the female pelvic floor dysfunction using the finite element method
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen , Germany, 20.07.2015 - 23.07.2015  / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  - 
TY  - CHAP
A1  - Duong, Minh Tuan
A1  - Nguyen, N. H.
A1  - Staat, Manfred
T1  - Modeling and simulation of a growing mass by the Smoothed Finite Element Method (SFEM)
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen, Germany, 20.07.2015 - 23.07.2015  / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  - 
TY  - CHAP
A1  - Pham, Phu Tinh
A1  - Staat, Manfred
T1  - A simplification for shakedown analysis of hardening structures
T2  - Conference proceedings of the YIC GACM 2015 : 3rd ECCOMAS Young Investigators Conference and 6th GACM Colloquium on Computational Mechanics , Aachen , Germany, 20.07.2015 - 23.07.2015 / ed.: Stefanie Elgeti ; Jaan-Willem Simon
Y1  - 2015
SP  - 1
EP  - 4
PB  - RWTH Aachen University
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Duong, Minh Tuan
A1  - Nguyen, Nhu Huynh
A1  - Staat, Manfred
T1  - Physical response of hyperelastic models for composite materials and soft tissues
JF  - Asia pacific journal on computational engineering
Y1  - 2015
U6  - http://dx.doi.org/10.1186/s40540-015-0015-x
SN  - 2196-1166
VL  - 2
IS  - 3 (December 2015)
SP  - 1
EP  - 18
ER  - 
TY  - CHAP
A1  - Peloni, Alessandro
A1  - Ceriotti, Matteo
A1  - Dachwald, Bernd
T1  - Solar-Sailing Trajectory Design for Close-up NEA Observations Mission
T2  - 4th IAA Planetary Defense Conference - PDC 2015, 13-17 April 2015, Frascati, Roma, Italy
Y1  - 2015
N1  - IAA-PDC-15-P-19
ER  - 
TY  - JOUR
A1  - Cehreli, Ruksan
A1  - Akpinar, Hale
A1  - Temiz Artmann, Aysegül
A1  - Sagol, Ozgul
T1  - Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis
JF  - Gastroenterology Research
Y1  - 2015
U6  - http://dx.doi.org/10.14740/gr683w
SN  - 1918-2813
VL  - 8
IS  - 5
SP  - 265
EP  - 273
ER  - 
TY  - JOUR
A1  - Kowalski, Julia
A1  - Linder, Peter
A1  - Zierke, S.
A1  - Wulfen, B. van
A1  - Clemens, J.
A1  - Konstantinidis, K.
A1  - Ameres, G.
A1  - Hoffmann, R.
A1  - Mikucki, J.
A1  - Tulaczyk, S.
A1  - Funke, O.
A1  - Blandfort, D.
A1  - Espe, Clemens
A1  - Feldmann, Marco
A1  - Francke, Gero
A1  - Hiecker, S.
A1  - Plescher, Engelbert
A1  - Schöngarth, Sarah
A1  - Dachwald, Bernd
A1  - Digel, Ilya
A1  - Artmann, Gerhard
A1  - Eliseev, D.
A1  - Heinen, D.
A1  - Scholz, F.
A1  - Wiebusch, C.
A1  - Macht, S.
A1  - Bestmann, U.
A1  - Reineking, T.
A1  - Zetzsche, C.
A1  - Schill, K.
A1  - Förstner, R.
A1  - Niedermeier, H.
A1  - Szumski, A.
A1  - Eissfeller, B.
A1  - Naumann, U.
A1  - Helbing, K.
T1  - Navigation technology for exploration of glacier ice with maneuverable melting probes
JF  - Cold Regions Science and Technology
N2  - The Saturnian moon Enceladus with its extensive water bodies underneath a thick ice sheet cover is a potential candidate for extraterrestrial life. Direct exploration of such extraterrestrial aquatic ecosystems requires advanced access and sampling technologies with a high level of autonomy. A new technological approach has been developed as part of the collaborative research project Enceladus Explorer (EnEx). The concept is based upon a minimally invasive melting probe called the IceMole. The force-regulated, heater-controlled IceMole is able to travel along a curved trajectory as well as upwards. Hence, it allows maneuvers which may be necessary for obstacle avoidance or target selection. Maneuverability, however, necessitates a sophisticated on-board navigation system capable of autonomous operations. The development of such a navigational system has been the focal part of the EnEx project. The original IceMole has been further developed to include relative positioning based on in-ice attitude determination, acoustic positioning, ultrasonic obstacle and target detection integrated through a high-level sensor fusion. This paper describes the EnEx technology and discusses implications for an actual extraterrestrial mission concept.
Y1  - 2016
U6  - http://dx.doi.org/10.1016/j.coldregions.2015.11.006
SN  - 0165-232X
IS  - 123
SP  - 53
EP  - 70
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Grundmann, Jan Thimo
A1  - Dachwald, Bernd
A1  - Grimm, Christian D.
A1  - Kahle, Ralph
A1  - Koch, Aaron Dexter
A1  - Krause, Christian
A1  - Lange, Caroline
A1  - Quantius, Dominik
A1  - Ulamec, Stephan
T1  - Spacecraft for Hypervelocity Impact Research – An Overview of Capabilities, Constraints and the Challenges of Getting There
JF  - Procedia Engineering
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.proeng.2015.04.021
SN  - 1877-7058
N1  - Proceedings of the 2015 Hypervelocity Impact Symposium (HVIS 2015)
VL  - Vol. 103
SP  - 151
EP  - 158
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Grundmann, Jan Thimo
A1  - Bauer, Waldemar
A1  - Biele, Jens
A1  - Cordero, Frederico
A1  - Dachwald, Bernd
A1  - Koncz, Alexander
A1  - Krause, Christian
A1  - Mikschl, Tobias
A1  - Montenegro, Sergio
A1  - Quantius, Dominik
A1  - Ruffer, Michael
A1  - Sasaki, Kaname
A1  - Schmitz, Nicole
A1  - Seefeldt, Patric
A1  - Tóth, Norbert
A1  - Wejmo, Elisabet
T1  - From Sail to Soil – Getting Sailcraft Out of the Harbour on a Visit to One of Earth’s Nearest Neighbours
T2  - 4th IAA Planetary Denfense Conference - PDC 2015,  13-17 April 2015, Frascati, Roma, Italy
Y1  - 2015
ER  - 
TY  - CHAP
A1  - Pirovano, Laura
A1  - Seefeldt, Patric
A1  - Dachwald, Bernd
A1  - Noomen, Ron
T1  - Attitude and Orbital Dynamics Modeling for an Uncontrolled Solar-Sail Experiment in Low-Earth Orbit
T2  - 25th International Symposium on Spaceflight Dynamics, 2015, Munich, Germany
Y1  - 2015
ER  - 
TY  - CHAP
A1  - Digel, Ilya
A1  - Sadykov, R.
A1  - Temiz Artmann, Aysegül
A1  - Artmann, Gerhard
T1  - Changes in intestinal microflora in rats induced by oral exposure to low lead (II) concentrations
T2  - Lead Exposure and Poisoning: Clinical Symptoms, Medical Management and Preventive Strategies
Y1  - 2015
SN  - 9781634826990
SP  - 75
EP  - 99
PB  - Nova Science Publ.
ER  - 
TY  - JOUR
A1  - Goßmann, Matthias
A1  - Frotscher, Ralf
A1  - Linder, Peter
A1  - Bayer, Robin
A1  - Epple, U.
A1  - Staat, Manfred
A1  - Temiz Artmann, Aysegül
A1  - Artmann, Gerhard
T1  - Mechano-pharmacological characterization of cardiomyocytes derived from human induced pluripotent stem cells
JF  - Cellular physiology and biochemistry
N2  - Background/Aims: Common systems for the quantification of cellular contraction rely on animal-based models, complex experimental setups or indirect approaches. The herein presented CellDrum technology for testing mechanical tension of cellular monolayers and thin tissue constructs has the potential to scale-up mechanical testing towards medium-throughput analyses. Using hiPS-Cardiac Myocytes (hiPS-CMs) it represents a new perspective of drug testing and brings us closer to personalized drug medication. Methods: In the present study, monolayers of self-beating hiPS-CMs were grown on ultra-thin circular silicone membranes and deflect under the weight of the culture medium. Rhythmic contractions of the hiPS-CMs induced variations of the membrane deflection. The recorded contraction-relaxation-cycles were analyzed with respect to their amplitudes, durations, time integrals and frequencies. Besides unstimulated force and tensile stress, we investigated the effects of agonists and antagonists acting on Ca²⁺ channels (S-Bay K8644/verapamil) and Na⁺ channels (veratridine/lidocaine). Results: The measured data and simulations for pharmacologically unstimulated contraction resembled findings in native human heart tissue, while the pharmacological dose-response curves were highly accurate and consistent with reference data. Conclusion: We conclude that the combination of the CellDrum with hiPS-CMs offers a fast, facile and precise system for pharmacological, toxicological studies and offers new preclinical basic research potential.
KW  - Inotropic compounds
KW  - Pharmacology
KW  - Ion channels
KW  - CellDrum
KW  - Heart tissue culture
KW  - Induced pluripotent stem cells
KW  - Cardiac myocytes
Y1  - 2016
U6  - http://dx.doi.org/10.1159/000443124
SN  - 1421-9778 (Online)
SN  - 1015-8987 (Print)
VL  - 38
IS  - 3
SP  - 1182
EP  - 1198
PB  - Karger
CY  - Basel
ER  - 
TY  - JOUR
A1  - Frotscher, Ralf
A1  - Muanghong, Danita
A1  - Dursun, Gözde
A1  - Goßmann, Matthias
A1  - Temiz Artmann, Aysegül
A1  - Staat, Manfred
T1  - Sample-specific adaption of an improved electro-mechanical model of in vitro cardiac tissue
JF  - Journal of Biomechanics
N2  - We present an electromechanically coupled computational model for the investigation of a thin cardiac tissue construct consisting of human-induced pluripotent stem cell-derived atrial, ventricular and sinoatrial cardiomyocytes. The mechanical and electrophysiological parts of the finite element model, as well as their coupling are explained in detail. The model is implemented in the open source finite element code Code_Aster and is employed for the simulation of a thin circular membrane deflected by a monolayer of autonomously beating, circular, thin cardiac tissue. Two cardio-active drugs, S-Bay K8644 and veratridine, are applied in experiments and simulations and are investigated with respect to their chronotropic effects on the tissue. These results demonstrate the potential of coupled micro- and macroscopic electromechanical models of cardiac tissue to be adapted to experimental results at the cellular level. Further model improvements are discussed taking into account experimentally measurable quantities that can easily be extracted from the obtained experimental results. The goal is to estimate the potential to adapt the presented model to sample specific cell cultures.
KW  - hiPS cardiomyocytes
KW  - Homogenization
KW  - Hodgkin–Huxley models
KW  - Frequency adaption
KW  - Electromechanical modeling
KW  - Drug simulation
KW  - Computational biomechanics
KW  - Cardiac tissue
Y1  - 2016
U6  - http://dx.doi.org/10.1016/j.jbiomech.2016.01.039
SN  - 0021-9290 (Print)
SN  - 1873-2380 (Online)
VL  - 49
IS  - 12
SP  - 2428
EP  - 2435
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Jung, Alexander
A1  - Staat, Manfred
A1  - Müller, Wolfram
T1  - Effect of wind on flight style optimisation in ski jumping
T2  - 15th International Symposium on Computer Simulation in Biomechanics ; July 9th-11th 2015, Edinburgh, UK
Y1  - 2016
SP  - 53
EP  - 54
PB  - The University of Edinburgh ; Loughborough University
CY  - Edinburgh
ER  - 
TY  - JOUR
A1  - Hauser, C.
A1  - Kotliar, Konstantin
A1  - Tholen, S.
A1  - Hasenau, A.
A1  - Suttmann, Y.
A1  - Renders, L.
A1  - Heemann, U.
A1  - Baumann, M.
A1  - Schmaderer, C.
T1  - Dynamische retinale Gefäßreaktion bei Hämodialysepatienten
JF  - Nieren- und Hochdruckkrankheiten
Y1  - 2015
U6  - http://dx.doi.org/10.5414/NHX01743a
SN  - 0300-5224
VL  - 44
IS  - 11
SP  - 480
EP  - 480
PB  - Dustri-Verlag
CY  - Oberhaching
ER  - 
TY  - CHAP
A1  - Peloni, A.
A1  - Ceriotti, M.
A1  - Dachwald, Bernd
T1  - Preliminary trajectory design of a multiple NEO rendezvous mission through solar sailing
T2  - Proceedings of the International Astronautical Congress, IAC, Vol. 8, 2014
Y1  - 2015
SN  - 978-1-63439-986-9
SP  - 5352
EP  - 5366
PB  - Curran
CY  - Red Hook, NY
ER  - 
TY  - JOUR
A1  - Hackl, Michael
A1  - Müller, Lars-Peter
A1  - Staat, Manfred
A1  - Kahmann, Stephanie Lucina
A1  - Wegmann, Kilian
T1  - Proximal phalangeal neck fractures of the hand — a biomechanical comparison of three fixation techniques
JF  - Knee surgery, sports traumatology, arthroscopy
N2  - Plate osteosynthesis of displaced proximal phalangeal neck fractures of the hand allows early mobilization due to a stable internal fixation. Nevertheless, joint stiffness—because of soft tissue irritation—represents a common complication leading to high complication rates. Del Pinal et al. recently reported promising clinical results for a new, minimally invasive fixation technique with a cannulated headless intramedullary compression screw. Hence, the aim of this study was to compare plate fixation of proximal phalangeal neck fractures to less two less invasive techniques: Crossed k-wire fixation and intramedullary screw fixation. We hypothesized that these fixation techniques provide inferior stability when compared to plate osteosynthesis.
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s00167-016-4080-7
SN  - 0942-2056
VL  - Volume 24
IS  - Supplement 1
SP  - 148
EP  - 149
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Hackl, Michael
A1  - Kahmann, Stephanie Lucina
A1  - Wegmann, Kilian
A1  - Ries, Christian
A1  - Staat, Manfred
A1  - Müller, Lars-Peter
T1  - Shortening osteotomy of the proximal radius — a treatment option for isolated osteoarthritis of the lateral column of the elbow joint?
JF  - Knee surgery, sports traumatology, arthroscopy
N2  - Treatment of posttraumatic osteoarthritis of the radial column of the elbow joint remains a challenging yet common issue.
While partial joint replacement leads to high revision rates, radial head excision has shown to severely increase joint instability. Shortening osteotomy of the radius could be an option to decrease the contact pressure of the radiohumeral joint and thereby pain levels without causing valgus instability. Hence, the aim of this biomechanical study was to evaluate the effects of radial shortening on axial load distribution and valgus stability of the elbow joint.
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s00167-016-4080-7
SN  - 0942-2056
VL  - Volume 24
IS  - Supplement 1
SP  - 128
EP  - 129
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Hackl, Michael
A1  - Leschinger, T.
A1  - Staat, Manfred
A1  - Müller, Lars-Peter
A1  - Wegmann, Kilian
T1  - Reconstruction of the interosseous membrane in the Essex Lopresti lesion — a biomechanical evaluation
JF  - Knee surgery, sports traumatology, arthroscopy
N2  - Surgical reconstruction of the interosseous membrane (IOM) could restore longitudinal forearm stability to avoid persisting disability due to capituloradial and ulnocarpal impingement in Essex Lopresti lesions. This biomechanical study aimed to assess longitudinal forearm stability of intact specimens, after sectioning of the IOM and after reconstruction with a TightRope construct using either a single or double bundle technique.
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s00167-016-4080-7
SN  - 0942-2056
VL  - Volume 24
IS  - Supplement 1
SP  - 130
EP  - 131
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Wegmann, Kilian
A1  - Hackl, Michael
A1  - Staat, Manfred
A1  - Mayer, Katharina
A1  - Müller, Lars-Peter
T1  - Double plate osteosynthesis of proximal ulna fractures: biomechanical and clinical results
JF  - Knee surgery, sports traumatology, arthroscopy
N2  - While plate fixation of proximal ulna fractures might lead to superior clinical results compared to tension band wiring, regular plates represent an established risk factor for wound complications. The olecranon double plates (Medartis, Basel, CH) might decrease complications related to the osteosynthesis because of their low profile and better anatomical fit. This study aimed to evaluate the biomechanical performance and clinical results of the olecranon double plates.
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s00167-016-4079-0
SN  - 0942-2056
VL  - Volume 24
IS  - Supplement 1
SP  - 58
EP  - 59
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Pookhalil, Ali
A1  - Amoabediny, Ghassem
A1  - Tabesh, Hadi
A1  - Behbahani, Mehdi
A1  - Mottaghy, Khosrow
T1  - A new approach for semiempirical modeling of mechanical blood trauma
JF  - The international journal of artificial organs
N2  - Purpose
Two semi-empirical models were recently published, both making use of existing literature data, but each taking into account different physical phenomena that trigger hemolysis. In the first model, hemoglobin (Hb) release is described as a permeation procedure across the membrane, assuming a shear stress-dependent process (sublethal model). The second model only accounts for hemoglobin release that is caused by cell membrane breakdown, which occurs when red blood cells (RBC) undergo mechanically induced shearing for a period longer than the threshold time (nonuniform threshold model). In this paper, we introduce a model that considers the hemolysis generated by both these possible phenomena.
Methods
Since hemolysis can possibly be caused by permeation of hemoglobin through the RBC functional membrane as well as by release of hemoglobin from RBC membrane breakdown, our proposed model combines both these models. An experimental setup consisting of a Couette device was utilized for validation of our proposed model.
Results
A comparison is presented between the damage index (DI) predicted by the proposed model vs. the sublethal model vs. the nonthreshold model and experimental datasets. This comparison covers a wide range of shear stress for both human and porcine blood. An appropriate agreement between the measured DI and the DI predicted by the present model was obtained.
Conclusions
The semiempirical hemolysis model introduced in this paper aims for significantly enhanced conformity with experimental data. Two phenomenological outcomes become possible with the proposed approach: an estimation of the average time after which cell membrane breakdown occurs under the applied conditions, and a prediction of the ratio between the phenomena involved in hemolysis.
Y1  - 2016
U6  - http://dx.doi.org/10.5301/ijao.5000474
SN  - 1724-6040
VL  - 39
IS  - 4
SP  - 171
EP  - 177
PB  - Sage
CY  - London
ER  - 
TY  - CHAP
A1  - Bhattarai, Aroj
A1  - Staat, Manfred
ED  - Erni, Daniel
T1  - Female pelvic floor dysfunction: progress weakening of the support system
T2  - 1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen
N2  - The structure of the female pelvic floor (PF) is an inter-related system of bony pelvis,muscles, pelvic organs, fascias, ligaments, and nerves with multiple functions. Mechanically, thepelvic organ support system are of two types: (I) supporting system of the levator ani (LA) muscle,and (II) the suspension system of the endopelvic fascia condensation [1], [2]. Significantdenervation injury to the pelvic musculature, depolimerization of the collagen fibrils of the softvaginal hammock, cervical ring and ligaments during pregnancy and vaginal delivery weakens thenormal functions of the pelvic floor. Pelvic organ prolapse, incontinence, sexual dysfunction aresome of the dysfunctions which increases progressively with age and menopause due toweakened support system according to the Integral theory [3]. An improved 3D finite elementmodel of the female pelvic floor as shown in Fig. 1 is constructed that: (I) considers the realisticsupport of the organs to the pelvic side walls, (II) employs the improvement of our previous FEmodel [4], [5] along with the patient based geometries, (III) incorporates the realistic anatomy andboundary conditions of the endopelvic (pubocervical and rectovaginal) fascia, and (IV) considersvarying stiffness of the endopelvic fascia in the craniocaudal direction [3]. Several computationsare carried out on the presented computational model with healthy and damaged supportingtissues, and comparisons are made to understand the physiopathology of the female PF disorders.
Y1  - 2016
U6  - http://dx.doi.org/10.17185/duepublico/40821
SP  - 11
EP  - 12
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Jung, Alexander
A1  - Staat, Manfred
ED  - Erni, Daniel
T1  - Computing olympic gold: Ski jumping as an example
T2  - 1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen
Y1  - 2016
SN  - 978-3-940402-06-6
U6  - http://dx.doi.org/10.17185/duepublico/40821
SP  - 54
EP  - 55
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Kahmann, Stephanie
A1  - Hackl, Michael
A1  - Wegmann, Kilian
A1  - Müller, Lars-Peter
A1  - Staat, Manfred
ED  - Erni, Daniel
T1  - Impact of a proximal radial shortening osteotomy on the distribution of forces and the stability of the elbow
T2  - 1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen
N2  - The human arm consists of the humerus (upper arm), the medial ulna and the lateral radius (forearm). The joint between the humerus and the ulna is called humeroulnar joint and the joint between the humerus and the radius is called humeroradial joint. Lateral and medial collateral ligaments stabilize the elbow. Statistically, 2.5 out of 10,000 people suffer from radial head fractures [1]. In these fractures the cartilage is often affected. Caused by the injured cartilage, degenerative diseases like posttraumatic arthrosis may occur. The resulting pain and reduced range of motion have an impact on the patient’s quality of life. Until now, there has not been a treatment which allows typical loads in daily life activities and offers good long-term results. A new surgical approach was developed with the motivation to reduce the progress of the posttraumatic arthrosis. Here, the radius is shortened by 3 mm in the proximal part [2]. By this means, the load of the radius is intended to be reduced due to a load shift to the ulna. Since the radius is the most important stabilizer of the elbow it has to be confirmed that the stability is not affected. In the first test (Fig. 1 left), pressure distributions within the humeroulnar and humeroradial joints a native and a shortened radius were measured using resistive pressure sensors (I5076 and I5027, Tekscan, USA). The humerus was loaded axially in a tension testing machine (Z010, Zwick Roell, Germany) in 50 N steps up to 400 N. From the humerus the load is transmitted through both the radius and the ulna into the hand which is fixed on the ground. In the second test (Fig. 1 right), the joint stability was investigated using a digital image correlation system to measure the displacement of the ulna. Here, the humerus is fixed with a desired flexion angle and the unconstrained forearm lies on the ground. A rope connects the load actuator with a hook fixed in the ulna. A guide roller is used so that the rope pulls the ulna horizontally when a tensile load is applied. This creates a moment about the elbow joint with a maximum value of 7.5 Nm. Measurements were performed with varying flexion angles (0°, 30°, 60°, 90°, 120°). For both tests and each measurement, seven specimens were used. Student ́s t-test was employed to determine whether the mean values of the measurements in native specimen and operated specimens differ significantly.
Y1  - 2016
U6  - http://dx.doi.org/10.17185/duepublico/40821
SP  - 7
EP  - 8
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - BOOK
A1  - Iomdina, E. N.
A1  - Bauer, S. M.
A1  - Kotliar, Konstantin
T1  - БИОМЕХАНИКА ГЛАЗА: ТЕОРЕТИЧЕСКИЕ АСПЕКТЫ И КЛИНИЧЕСКИЕ ПРИЛОЖЕНИЯ
T2  - Eye biomechanics : theoretical aspects and clinical applications
Y1  - 2015
SN  - 978-5-903025-57-2
PB  - Real Time
CY  - Moscow
ER  - 
TY  - CHAP
A1  - Tran, Ngoc Trinh
A1  - Tran, Thanh Ngoc
A1  - Matthies, Hermann G.
A1  - Stavroulakis, Georgios Eleftherios
A1  - Staat, Manfred
T1  - FEM Shakedown of uncertain structures by chance constrained programming
T2  - PAMM Proceedings in Applied Mathematics and Mechanics
Y1  - 2016
U6  - http://dx.doi.org/10.1002/pamm.201610346
SN  - 1617-7061
N1  - Special Issue:
Joint 87th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM) and Deutsche Mathematiker-Vereinigung
VL  - 16
IS  - 1
SP  - 715
EP  - 716
ER  - 
TY  - JOUR
A1  - Levers, A.
A1  - Staat, Manfred
A1  - Laack, Walter van
T1  - Analysis of the long-term effect of the MBST® nuclear magnetic resonance therapy on gonarthrosis
JF  - Orthopedic Practice
Y1  - 2016
VL  - 47
IS  - 11
SP  - 521
EP  - 528
ER  - 
TY  - JOUR
A1  - Niedermeyer, Angela
A1  - Zhou, Bei
A1  - Dursun, Gözde
A1  - Temiz Artmann, Aysegül
A1  - Markert, Bernd
T1  - An examination of tissue engineered scaffolds in a bioreactor
JF  - Proceedings in Applied Mathematics and Mechanics PAMM
N2  - Replacement tissues, designed to fill in articular cartilage defects, should exhibit the same properties as the native material. The aim of this study is to foster the understanding of, firstly, the mechanical behavior of the material itself and, secondly, the influence of cultivation parameters on cell seeded implants as well as on cell migration into acellular implants. In this study, acellular cartilage replacement material is theoretically, numerically and experimentally investigated regarding its viscoelastic properties, where a phenomenological model for practical applications is developed. Furthermore, remodeling and cell migration are investigated.
Y1  - 2016
U6  - http://dx.doi.org/10.1002/pamm.201610038
SN  - 1617-7061
N1  - Joint Annual Meeting of DMV and GAMM 2016, 87th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM) and Deutsche Mathematiker-Vereinigung (DMV), Braunschweig, DE, Mar 7-11, 2016
VL  - 16
IS  - 1
SP  - 99
EP  - 100
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Tran, Ngoc Trinh
A1  - Tran, Thanh Ngoc
A1  - Matthies, H. G.
A1  - Stavroulakis, G. E.
A1  - Staat, Manfred
ED  - Papadrakakis, M.
T1  - Shakedown analysis of plate bending analysis under stochastic uncertainty by chance constrained programming
T2  - ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5–10 June 2016
Y1  - 2016
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Mit Statistik gemeistert: perfekte Augentropfen und idealer Screeningtest : Möglichkeiten und Grenzen statistischer Methoden beim Glaukom
JF  - Der Ophthalmologe: Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
N2  - Hintergrund
Die Anwendung und das Verständnis von Statistik sind sehr wichtig für die biomedizinische Forschung und für die klinische Praxis. Dies gilt insbesondere auch zur Abschätzung der Möglichkeiten unterschiedlichster Diagnostik- und Therapieoptionen beim Glaukom. Die scheinbare Komplexität der Statistik, die zum Teil dem „gesunden Menschenverstand“ zu widersprechen scheint, zusammen mit der nur vorsichtigen Akzeptanz der Statistik bei vielen Medizinern können zu bewussten und unbewussten Manipulationen bei der Datendarstellung und -interpretation führen.

Ziel der Arbeit
Ziel ist die verständliche Darstellung einiger typischer Fehler in der medizinisch-statistischen Datenbehandlung.

Material und Methoden
Anhand hypothetischer Beispiele aus der Glaukomdiagnostik erfolgen die Darstellung der Wirkung eines hypotensiven Medikamentes sowie die Beurteilung der Ergebnisse eines diagnostischen Tests. Es werden die typischsten statistischen Einsatzbereiche und Irrtumsquellen ausführlich und verständlich analysiert

Ergebnisse
Mechanismen von Datenmanipulation und falscher Dateninterpretation werden aufgeklärt. Typische Irrtumsquellen bei der statistischen Auswertung und Datendarstellung werden dabei erläutert.

Schlussfolgerungen
Die erläuterten praktischen Beispiele zeigen die Notwendigkeit, die Grundlagen der Statistik zu verstehen und korrekt anwenden zu können. Fehlendes Grundlagenwissen und Halbwissen der medizinischen Statistik können zu folgenschweren Missverständnissen und falschen Entscheidungen in der medizinischen Forschung, aber auch in der klinischen Praxis führen.
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s00347-016-0312-y
SN  - 0941-293X
SN  - 1433-0423
N1  - Englischer Titel: Mastered with statistics: perfect eye drops and ideal screening test : possibilities and limits of statistical methods for glaucoma
IS  - 113
SP  - 838
EP  - 843
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Hackl, M.
A1  - Andermahr, J.
A1  - Staat, Manfred
A1  - Bremer, I.
A1  - Borggrefe, J.
A1  - Prescher, A.
A1  - Müller, L. P.
A1  - Wegmann, K.
T1  - Suture button reconstruction of the central band of the interosseous membrane in Essex-Lopresti lesions: a comparative biomechanical investigation
JF  - The Journal of Hand Surgery (European Volume)
Y1  - 2017
U6  - http://dx.doi.org/10.1177/1753193416665943
SN  - 2043-6289 (Online)
SN  - 1753-1934 (Print)
VL  - 42
IS  - 4
SP  - 370
EP  - 376
PB  - Sage
CY  - London
ER  - 
TY  - CHAP
A1  - Bhattarai, Aroj
A1  - Frotscher, Ralf
A1  - Staat, Manfred
ED  - Natal Jorge, Renato
T1  - Significance of fibre geometry on passive-active response of pelvic muscles to evaluate pelvic dysfunction
T2  - BioMedWomen: Proceedings of the international conference on clinical and bioengineering for women's health
Y1  - 2016
SN  - 978-1-138-02910-1
SP  - 185
EP  - 188
PB  - CRC Press
CY  - Boca Raton
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Limit and shakedown analysis under uncertainty
JF  - Tap chi Khoa hoc & ung dung - Dai hoc Ton Duc Thang
Y1  - 2012
N1  - = Journal of Applied Sciences - Ton Duc Thang University
VL  - 19
SP  - 45
EP  - 47
ER  - 
TY  - JOUR
A1  - Belavy, Daniel L.
A1  - Albracht, Kirsten
A1  - Bruggemann, Gert-Peter
A1  - Vergroesen, Pieter-Paul A.
A1  - Dieen, Jaap H. van
T1  - Can exercise positively influence the intervertebral disc?
JF  - Sports Medicine
N2  - To better understand what kinds of sports and exercise could be beneficial for the intervertebral disc (IVD), we performed a review to synthesise the literature on IVD adaptation with loading and exercise. The state of the literature did not permit a systematic review; therefore, we performed a narrative review. The majority of the available data come from cell or whole-disc loading models and animal exercise models. However, some studies have examined the impact of specific sports on IVD degeneration in humans and acute exercise on disc size. Based on the data available in the literature, loading types that are likely beneficial to the IVD are dynamic, axial, at slow to moderate movement speeds, and of a magnitude experienced in walking and jogging. Static loading, torsional loading, flexion with compression, rapid loading, high-impact loading and explosive tasks are likely detrimental for the IVD. Reduced physical activity and disuse appear to be detrimental for the IVD. We also consider the impact of genetics and the likelihood of a ‘critical period’ for the effect of exercise in IVD development. The current review summarises the literature to increase awareness amongst exercise, rehabilitation and ergonomic professionals regarding IVD health and provides recommendations on future directions in research.
KW  - Intradiscal Pressure
KW  - Annulus Fibrosus
KW  - Disc Degeneration
KW  - Nucleus Pulposus
KW  - Intervertebral Disc
Y1  - 2016
U6  - http://dx.doi.org/10.1007/s40279-015-0444-2
SN  - 1179-2035
VL  - 46
IS  - 4
SP  - 473
EP  - 485
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Yang, Peng-Fei
A1  - Kriechbaumer, Andreas
A1  - Albracht, Kirsten
A1  - Sanno, Maximilian
A1  - Ganse, Bergita
A1  - Koy, Timmo
A1  - Shang, Peng
A1  - Brüggemann, Gert-Peter
A1  - Müller, Lars Peter
A1  - Rittweger, Jörn
T1  - On the relationship between tibia torsional deformation and regional muscle contractions in habitual human exercises in vivo
JF  - Journal of Biomechanics
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.jbiomech.2014.12.031
SN  - 0021-9290
VL  - 48
IS  - 3
SP  - 456
EP  - 464
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Seynnes, O. R.
A1  - Bojsen-Moller, J.
A1  - Albracht, Kirsten
A1  - Arndt, A.
A1  - Cronin, N. J.
A1  - Finni, T.
A1  - Magnusson, S. P.
T1  - Ultrasound-based testing of tendon mechanical properties: a critical evaluation
JF  - Journal of Applied Physiology
Y1  - 2015
U6  - http://dx.doi.org/10.1152/japplphysiol.00849.2014
SN  - 8750-7587
VL  - 118
IS  - 2
SP  - 133
EP  - 141
ER  - 
TY  - JOUR
A1  - Albracht, Kirsten
A1  - Arampatzis, Adamantios
T1  - Exercise-induced changes in triceps surae tendon stiffness and muscle strength affect running economy in humans
JF  - European Journal of Applied Physiology
Y1  - 2013
U6  - http://dx.doi.org/10.1007/s00421-012-2585-4
SN  - 1439-6327
VL  - 113
IS  - 6
SP  - 1605
EP  - 1615
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Karamanidis, Kiros
A1  - Albracht, Kirsten
A1  - Braunstein, Bjoern
A1  - Catala, Maria Moreno
A1  - Goldmann, Jan-Peter
A1  - Brüggemann, Gert-Peter
T1  - Lower leg musculoskeletal geometry and sprint performance
JF  - Gait and Posture
N2  - The purpose of this study was to investigate whether sprint performance is related to lower leg musculoskeletal geometry within a homogeneous group of highly trained 100-m sprinters. Using a cluster analysis, eighteen male sprinters were divided into two groups based on their personal best (fast: N = 11, 10.30 ± 0.07 s; slow: N = 7, 10.70 ± 0.08 s). Calf muscular fascicle arrangement and Achilles tendon moment arms (calculated by the gradient of tendon excursion versus ankle joint angle) were analyzed for each athlete using ultrasonography. Achilles tendon moment arm, foot and ankle skeletal geometry, fascicle arrangement as well as the ratio of fascicle length to Achilles tendon moment arm showed no significant (p > 0.05) correlation with sprint performance, nor were there any differences in the analyzed musculoskeletal parameters between the fast and slow sprinter group. Our findings provide evidence that differences in sprint ability in world-class athletes are not a result of differences in the geometrical design of the lower leg even when considering both skeletal and muscular components.
Y1  - 2011
U6  - http://dx.doi.org/10.1016/j.gaitpost.2011.03.009
SN  - 0966-6362
VL  - 34
IS  - 1
SP  - 138
EP  - 141
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Arampatzis, Adamantios
A1  - Karamanidis, Kiros
A1  - Mademli, Lida
A1  - Albracht, Kirsten
T1  - Plasticity of the human tendon to short and long-term mechanical loading
JF  - Exercise and Sport Sciences Reviews
Y1  - 2009
U6  - http://dx.doi.org/10.1097/JES.0b013e31819c2e1d
SN  - 1538-3008
VL  - 37
IS  - 2
SP  - 66
EP  - 72
ER  - 
TY  - JOUR
A1  - Albracht, Kirsten
A1  - Arampatzis, A.
A1  - Baltzopoulos, V.
T1  - Assessment of muscle volume and physiological cross-sectional area of the human triceps surae muscle in vivo
JF  - Journal of Biomechanics
Y1  - 2008
U6  - http://dx.doi.org/10.1016/j.jbiomech.2008.04.020
SN  - 0021-9290
VL  - 41
SP  - 2211
EP  - 2218
ER  - 
TY  - JOUR
A1  - Arampatzis, Adamantios
A1  - Karamanidis, Kiros
A1  - Albracht, Kirsten
T1  - Adaptational responses of the human Achilles tendon by modulation of the applied cyclic strain magnitude
JF  - Journal of Experimental Biology
Y1  - 2007
U6  - http://dx.doi.org/10.1242/jeb.003814
SN  - 0022-0949
VL  - 210
IS  - 15
SP  - 2743
EP  - 2753
ER  - 
TY  - JOUR
A1  - Albracht, Kirsten
A1  - Arampatzis, Adamantios
T1  - Influence of the mechanical properties of the muscle-tendon unit on force generation in runners with different running economy
JF  - Biological Cybernetics
Y1  - 2006
U6  - http://dx.doi.org/10.1007/s00422-006-0070-z
SN  - 1432-0770
VL  - 95
IS  - 1
SP  - 87
EP  - 96
ER  - 
TY  - CHAP
A1  - Abel, Thomas
A1  - Bonin, Dominik
A1  - Albracht, Kirsten
A1  - Zeller, Sebastian
A1  - Burkett, Brendan
T1  - Kinematische Untersuchung der Kurbelbewegung im Handcycling: Entwicklung einer sportartspezifischen Methode
T2  - Behindertensport 1951-2011 : Historische und aktuelle Aspekte im nationalen und internationalen Dialog
Y1  - 2015
SN  - 9783898997249
SP  - 82
EP  - 91
PB  - Meyer & Meyer
CY  - Aachen
ER  - 
TY  - CHAP
A1  - Kolditz, Melanie
A1  - Albin, Thivaharan
A1  - Albracht, Kirsten
A1  - Brüggemann, Gert-Peter
A1  - Abel, Dirk
T1  - Isokinematic leg extension training with an industrial robot
T2  - 6th IEEE RAS/EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob) June 26-29, 2016. UTown, Singapore
Y1  - 2016
U6  - http://dx.doi.org/10.1109/BIOROB.2016.7523750
SP  - 950
EP  - 955
ER  - 
TY  - CHAP
A1  - Konstantinidis, K.
A1  - Kowalski, Julia
A1  - Martinez, C. F.
A1  - Dachwald, Bernd
A1  - Ewerhart, D.
A1  - Förstner, R.
T1  - Some necessary technologies for in-situ astrobiology on enceladus
T2  - Proceedings of the International Astronautical Congress
Y1  - 2015
SN  - 978-151081893-4
N1  - 6th International Astronautical Congress 2015: Space - The Gateway for Mankind's Future, IAC 2015; Jerusalem; Israel; 12 October 2015 through 16 October 2015
SP  - 1354
EP  - 1372
ER  - 
TY  - CHAP
A1  - Goldmann, Jan-Peter
A1  - Braunstein, Bjoern
A1  - Heinrich, Kai
A1  - Sanno, Maximilian
A1  - Stäudle, Benjamin
A1  - Ritzdorf, Wolfgang
A1  - Brüggemann, Gert-Peter
A1  - Albracht, Kirsten
T1  - Joint work of the take-off leg during elite high jump
T2  - Proceedings of the 33th International Conference on Biomechanics in Sports (ISBS)
Y1  - 2015
ER  - 
TY  - CHAP
A1  - Droszez, Anna
A1  - Sanno, Maximilian
A1  - Goldmann, Jan-Peter
A1  - Albracht, Kirsten
A1  - Brüggemann, Gerd-Peter
A1  - Braunstein, Bjoern
T1  - Differences between take-off behavior during vertical jumps and two artistic elements
T2  - 34th International Conference of Biomechanics in Sport, Tsukuba, Japan, July 18-22, 2016
Y1  - 2016
SN  - 1999-4168
SP  - 577
EP  - 580
ER  - 
TY  - CHAP
A1  - Abel, Thomas
A1  - Bonin, Dominik
A1  - Albracht, Kirsten
A1  - Zeller, Sebastian
A1  - Brüggemann, Gert-Peter
A1  - Burkett, Brendan
A1  - Strüder, Heiko K.
T1  - Kinematic profile of the elite handcyclist
T2  - 28th  International Conference on Biomechanics in Sports, Marquette, Michigan, USA, July 19 – 23, 2010
Y1  - 2017
SN  - 1999-4168
SP  - 140
EP  - 141
ER  - 
TY  - CHAP
A1  - Braunstein, Bjoern
A1  - Goldmann, Jan-Peter
A1  - Albracht, Kirsten
A1  - Sanno, Maximilian
A1  - Willwacher, Steffen
A1  - Heinrich, Kai
A1  - Herrmann, Volker
A1  - Brüggemann, Gert-Peter
T1  - Joint specific contribution of mechanical power and work during acceleration and top speed in elite sprinters
T2  - 31 International Conference on Biomechanics in Sports, Taipei, Taiwan, July 07 - July 22, 2013
Y1  - 2013
SN  - 1999-4168
ER  - 
TY  - JOUR
A1  - Lanzl, I.
A1  - Kotliar, Konstantin
T1  - Können Anti-VEGF-Injektionen Glaukom oder okuläre Hypertension verursachen?
T1  - Can Anti-VEGF Injections Cause Glaucoma or Ocular Hypertension?
JF  - Klinische Monatsblätter für Augenheilkunde
Y1  - 2017
U6  - http://dx.doi.org/10.1055/s-0043-101819
SN  - 0023-2165
VL  - 234
IS  - 2
SP  - 191
EP  - 193
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Hackl, Michael
A1  - Wegmann, Kilian
A1  - Kahmann, Stephanie Lucina
A1  - Heinze, Nicolai
A1  - Staat, Manfred
A1  - Neiss, Wolfram F.
A1  - Scaal, Martin
A1  - Müller, Lars P.
T1  - Radial shortening osteotomy reduces radiocapitellar contact pressures while preserving valgus stability of the elbow
JF  - Knee Surgery, Sports Traumatology, Arthroscopy
Y1  - 2017
U6  - http://dx.doi.org/10.1007/s00167-017-4468-z
SN  - 1433-7347
VL  - 25
IS  - 7
SP  - 2280
EP  - 2288
PB  - Springer
CY  - Berlin
ER  - 
TY  - THES
A1  - Albracht, Kirsten
T1  - Influence of mechanical properties of the leg extensor muscletendon units on running economy
Y1  - 2010
N1  - Cologne, German Sport Univ., Diss., 2010
PB  - Deutsche Sporthochschule Köln
CY  - Köln
ER  - 
TY  - JOUR
A1  - Kolditz, Melanie
A1  - Albin, Thivaharan
A1  - Brüggemann, Gert-Peter
A1  - Abel, Dirk
A1  - Albracht, Kirsten
T1  - Robotergestütztes System für ein verbessertes neuromuskuläres Aufbautraining der Beinstrecker
JF  - at - Automatisierungstechnik
N2  - Neuromuskuläres Aufbautraining der Beinstrecker ist ein wichtiger Bestandteil in der Rehabilitation und Prävention von Muskel-Skelett-Erkrankungen. Effektives Training erfordert hohe Muskelkräfte, die gleichzeitig hohe Belastungen von bereits geschädigten Strukturen bedeuten. Um trainingsinduzierte Schädigungen zu vermeiden, müssen diese Kräfte kontrolliert werden. Mit heutigen Trainingsgeräten können diese Ziele allerdings nicht erreicht werden. Für ein sicheres und effektives Training sollen durch den Einsatz der Robotik, Sensorik, eines Regelkreises sowie Muskel-Skelett-Modellen Belastungen am Zielgewebe direkt berechnet und kontrolliert werden. Auf Basis zweier Vorstudien zu möglichen Stellgrößen wird der Aufbau eines robotischen Systems vorgestellt, das sowohl für Forschungszwecke als auch zur Entwicklung neuartiger Trainingsgeräte verwendet werden kann.
Y1  - 2016
U6  - http://dx.doi.org/10.1515/auto-2016-0044
SN  - 2196-677X
VL  - 64
IS  - 11
SP  - 905
EP  - 914
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Kolditz, Melanie
A1  - Albracht, Kirsten
A1  - Fasse, Alessandro
A1  - Albin, Thivaharan
A1  - Brüggemann, Gert-Peter
A1  - Abel, Dirk
T1  - Evaluation of an industrial robot as a leg press training device
T2  - XV International Symposium on Computer Simulation in Biomechanics July 9th – 11th 2015, Edinburgh, UK
Y1  - 2015
SP  - 41
EP  - 42
ER  - 
TY  - CHAP
A1  - Kolditz, Melanie
A1  - Albin, Thivaharan
A1  - Fasse, Alessandro
A1  - Brüggemann, Gert-Peter
A1  - Abel, Dirk
A1  - Albracht, Kirsten
T1  - Simulative Analysis of Joint Loading During Leg Press Exercise for Control Applications
T2  - IFAC-PapersOnLine
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.ifacol.2015.10.179
N1  - IFAC-PapersOnLine 48-20;
Conference Paper Archive
VL  - 48
IS  - 20
SP  - 435
EP  - 440
ER  - 
TY  - JOUR
A1  - Zange, Jochen
A1  - Schopen, Kathrin
A1  - Albracht, Kirsten
A1  - Gerlach, Darius A.
A1  - Frings-Meuthen, Petra
A1  - Maffiuletti, Nicola A.
A1  - Bloch, Wilhelm
A1  - Rittweger, Jörn
T1  - Using the Hephaistos orthotic device to study countermeasure effectiveness of neuromuscular electrical stimulation and dietary lupin protein supplementation, a randomised controlled trial
JF  - Plos one
Y1  - 2017
U6  - http://dx.doi.org/10.1371/journal.pone.0171562
VL  - 12
IS  - 2
ER  - 
TY  - JOUR
A1  - Ciritsis, Alexander
A1  - Horbach, Andreas
A1  - Staat, Manfred
A1  - Kuhl, Christiane K.
A1  - Kraemer, Nils Andreas
T1  - Porosity and tissue integration of elastic mesh implants evaluated in vitro and in vivo
JF  - Journal of Biomedical Materials Research: Part B:  Applied Biomaterials
N2  - Purpose
In vivo, a loss of mesh porosity triggers scar tissue formation and restricts functionality. The purpose of this study was to evaluate the properties and configuration changes as mesh deformation and mesh shrinkage of a soft mesh implant compared with a conventional stiff mesh implant in vitro and in a porcine model.

Material and Methods
Tensile tests and digital image correlation were used to determine the textile porosity for both mesh types in vitro. A group of three pigs each were treated with magnetic resonance imaging (MRI) visible conventional stiff polyvinylidene fluoride meshes (PVDF) or with soft thermoplastic polyurethane meshes (TPU) (FEG Textiltechnik mbH, Aachen, Germany), respectively. MRI was performed with a pneumoperitoneum at a pressure of 0 and 15 mmHg, which resulted in bulging of the abdomen. The mesh-induced signal voids were semiautomatically segmented and the mesh areas were determined. With the deformations assessed in both mesh types at both pressure conditions, the porosity change of the meshes after 8 weeks of ingrowth was calculated as an indicator of preserved elastic properties. The explanted specimens were examined histologically for the maturity of the scar (collagen I/III ratio).

Results
In TPU, the in vitro porosity increased constantly, in PVDF, a loss of porosity was observed under mild stresses. In vivo, the mean mesh areas of TPU were 206.8 cm2 (± 5.7 cm2) at 0 mmHg pneumoperitoneum and 274.6 cm2 (± 5.2 cm2) at 15 mmHg; for PVDF the mean areas were 205.5 cm2 (± 8.8 cm2) and 221.5 cm2 (± 11.8 cm2), respectively. The pneumoperitoneum-induced pressure increase resulted in a calculated porosity increase of 8.4% for TPU and of 1.2% for PVDF. The mean collagen I/III ratio was 8.7 (± 0.5) for TPU and 4.7 (± 0.7) for PVDF.

Conclusion
The elastic properties of TPU mesh implants result in improved tissue integration compared to conventional PVDF meshes, and they adapt more efficiently to the abdominal wall. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 827–833, 2018.
Y1  - 2018
U6  - http://dx.doi.org/10.1002/jbm.b.33877
SN  - 1552-4981
VL  - 106
IS  - 2
SP  - 827
EP  - 833
PB  - Wiley
CY  - New York, NY
ER  - 
TY  - CHAP
A1  - Duong, Minh Tuan
A1  - Nguyen, Nhu Huynh
A1  - Staat, Manfred
T1  - Physical response of hyperelastic models for composite materials and soft tissues
T2  - Advances in Composite Material
Y1  - 2017
SN  - 978-1-61896-300-0 (Hardcover), 978-1-61896-299-7 (Paperback)
N1  - Chapter 5
PB  - Scientific Research Publishing
CY  - Wuhan
ER  - 
TY  - JOUR
A1  - Michael, Hackl
A1  - Mayer, Katharina
A1  - Weber, Mareike
A1  - Staat, Manfred
A1  - van Riet, Roger
A1  - Burkhart, Klau Josef
A1  - Müller, Lars Peter
A1  - Wegmann, Kilian
T1  - Plate osteosynthesis of proximal ulna fractures : a biomechanical micromotion analysis
JF  - The journal of hand surgery
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.jhsa.2017.05.014
SN  - 0363-5023
VL  - 42
IS  - 10
SP  - 834.e1
EP  - 834.e7
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Abel, Alexander
A1  - Pérez-Viana, Daniel
A1  - Ciritsis, Bernard
A1  - Staat, Manfred
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Prevention of femur neck fractures through femoroplasty
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
SP  - 114
EP  - 115
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Birgel, Stefan
A1  - Leschinger, Tim
A1  - Wegmann, Kilian
A1  - Staat, Manfred
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Calculation of muscle forces and joint reaction loads in shoulder area via an OpenSim based computer calculation
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
N1  - In der Druckausgabe des Abstractbandes ist dieser Beitrag lose als Erratum beigefügt.
SP  - 116
EP  - 117
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Jabbari, Medisa
A1  - Bhattarai, Aroj
A1  - Anding, Ralf
A1  - Staat, Manfred
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Biomechanical simulation of different prosthetic meshes for repairing uterine/vaginal vault prolapse
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
SP  - 118
EP  - 119
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Suryoputri, Nathania
A1  - Ghaderi, Aydin
A1  - Linder, Peter
A1  - Kotliar, Konstantin
A1  - Göttler, Jens
A1  - Sorg, Christian
A1  - Grimmer, Timo
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Does hemodynamic response function change in Alzheimer disease?
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
SP  - 92
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Schneider, Oliver
A1  - Al Hakim, Taher
A1  - Kayser, Peter
A1  - Digel, Ilya
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Development and trials of a test chamber for ultrasound-assisted sampling of living cells from solid surfaces
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
SP  - 96
EP  - 97
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Schlemmer, Katharina
A1  - Porst, Dariusz
A1  - Bassam, Rasha
A1  - Artmann, Gerhard
A1  - Digel, Ilya
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Effects of nitric oxide (NO) and ATP on red blood cell phenotype and deformability
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
SP  - 100
EP  - 101
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Kuhlen, Max
A1  - Digel, Ilya
ED  - Erni, Daniel
ED  - Fischerauer, Alice
ED  - Himmel, Jörg
ED  - Seeger, Thomas
ED  - Thelen, Klaus
T1  - Fluorescence signatures and detection limits of ubiquitous terrestrial bio-compounds
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
SP  - 102
EP  - 103
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - de Honde, Lukas
A1  - Porst, Dariusz
A1  - Digel, Ilya
ED  - Fischerauer, Alice
T1  - A randomized, observational thermographic study of the neck region before and after a physiotherapeutic intervention
T2  - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West
Y1  - 2017
SN  - 978-3-9814801-9-1
U6  - http://dx.doi.org/10.17185/duepublico/43984
N1  - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017
SP  - 122
EP  - 123
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - JOUR
A1  - Horbach, Andreas
A1  - Duong, Minh Tuan
A1  - Staat, Manfred
T1  - Modelling of compressible and orthotropic surgical mesh implants based on optical deformation measurement
JF  - Journal of the mechanical behavior of biomedical materials
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.jmbbm.2017.06.012
SN  - 1751-6161
VL  - 74
SP  - 400
EP  - 410
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Tran, Linda
A1  - Mottaghy, K.
A1  - Arlt-Körfer, Sabine
A1  - Waluga, Christian
A1  - Behbahani, Mehdi
T1  - An experimental study of shear-dependent human platelet adhesion and underlying protein-binding mechanisms in a cylindrical Couette system
JF  - Biomedizinische Technik
Y1  - 2017
U6  - http://dx.doi.org/10.1515/bmt-2015-0034
SN  - 0013-5585
VL  - 62
IS  - 4
SP  - 383
EP  - 392
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Tran, N. T.
A1  - Tran, Thanh Ngoc
A1  - Matthies, M. G.
A1  - Stavroulakis, G. E.
A1  - Staat, Manfred
T1  - Shakedown Analysis Under Stochastic Uncertainty by Chance Constrained Programming
T2  - Advances in Direct Methods for Materials and Structures
N2  - In this paper we propose a stochastic programming method to analyse limit and shakedown of structures under uncertainty condition of strength. Based on the duality theory, the shakedown load multiplier formulated by the kinematic theorem is proved actually to be the dual form of the shakedown load multiplier formulated by static theorem. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) with three-node linear triangular elements is used for structural analysis.
Y1  - 2017
SN  - 978-3-319-59810-9
U6  - http://dx.doi.org/10.1007/978-3-319-59810-9_6
SP  - 85
EP  - 103
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Albanna, Walid
A1  - Lueke, Jan Niklas
A1  - Sjapic, Volha
A1  - Kotliar, Konstantin
A1  - Hescheler, Jürgen
A1  - Clusmann, Hans
A1  - Sjapic, Sergej
A1  - Alpdogan, Serdan
A1  - Schneider, Toni
A1  - Schubert, Gerrit Alexander
A1  - Neumaier, Felix
T1  - Electroretinographic Assessment of Inner Retinal Signaling in the Isolated and Superfused Murine Retina
JF  - Current Eye Research
Y1  - 2017
U6  - http://dx.doi.org/10.1080/02713683.2017.1339807
SN  - 1460-2202
IS  - Article in press
SP  - 1
EP  - 9
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Seifarth, Volker
A1  - Grosse, Joachim O.
A1  - Grossmann, Matthias
A1  - Janke, Heinz Peter
A1  - Arndt, Patrick
A1  - Koch, Sabine
A1  - Epple, Matthias
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Mechanical induction of bi-directional orientation of primary porcine bladder smooth muscle cells in tubular fibrin-poly(vinylidene fluoride) scaffolds for ureteral and urethral repair using cyclic and focal balloon catheter stimulation
JF  - Journal of Biomaterials Applications
Y1  - 2017
U6  - http://dx.doi.org/10.1177/0885328217723178
SN  - 1530-8022
VL  - 32
IS  - 3
SP  - 321
EP  - 330
PB  - Sage
CY  - London
ER  - 
TY  - GEN
A1  - Hackl, Michael
A1  - Wegmann, Kilian
A1  - Kahmann, Stephanie Lucina
A1  - Heinze, Nicolai
A1  - Staat, Manfred
A1  - Neiss, Wolfram F.
A1  - Scaal, Martin
A1  - Müller, Lars P.
T1  - Reply to the letter to the editor: shortening osteotomy of the proximal radius
T2  - Knee Surgery, Sports Traumatology, Arthroscopy
Y1  - 2017
U6  - http://dx.doi.org/10.1007/s00167-017-4666-8
VL  - 25
IS  - 10
SP  - 3328
EP  - 3329
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Hauser, Christine
A1  - Ortner, Marion
A1  - Muggenthaler, Claudia
A1  - Diehl-Schmid, Janine
A1  - Angermann, Susanne
A1  - Hapfelmeier, Alexander
A1  - Schmaderer, Christoph
A1  - Grimmer, Timo
T1  - Altered neurovascular coupling as measured by optical imaging: a biomarker for Alzheimer’s disease
JF  - Scientific Reports
Y1  - 2017
U6  - http://dx.doi.org/10.1038/s41598-017-13349-5
SN  - 2045-2322
N1  - Article 12906
VL  - 7
IS  - 1
SP  - 1
EP  - 11
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Werkhausen, Amelie
A1  - Albracht, Kirsten
A1  - Cronin, Neil J.
A1  - Meier, Rahel
A1  - Mojsen-Moeller, Jens
A1  - Seynnes, Olivier R.
T1  - Modulation of muscle-tendon interaction in the human triceps surae during an energy dissipation task
JF  - Journal of Experimental Biology
Y1  - 2017
U6  - http://dx.doi.org/10.1242/jeb.164111
SN  - 0022-0949
VL  - 220
IS  - 22
SP  - 4141
EP  - 4149
ER  - 
TY  - CHAP
A1  - Grundmann, Jan Thimo
A1  - Meß, Jan-Gerd
A1  - Biele, Jens
A1  - Seefeldt, Patric
A1  - Dachwald, Bernd
A1  - Spietz, Peter
A1  - Grimm, Christian D.
A1  - Spröwitz, Tom
A1  - Lange, Caroline
A1  - Ulamec, Stephan
T1  - Small spacecraft in small solar system body applications
T2  - IEEE Aerospace Conference 2017, Big Sky, Montana, USA
Y1  - 2017
SN  - 978-1-5090-1613-6
U6  - http://dx.doi.org/10.1109/AERO.2017.7943626
SP  - 1
EP  - 20
ER  - 
TY  - JOUR
A1  - Peloni, Alessandro
A1  - Dachwald, Bernd
A1  - Ceriotti, Matteo
T1  - Multiple near-earth asteroid rendezvous mission: Solar-sailing options
JF  - Advances in Space Research
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.asr.2017.10.017
SN  - 0273-1177
IS  - In Press, Corrected Proof
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bhattarai, Aroj
A1  - Jabbari, Medisa
A1  - Anding, Ralf
A1  - Staat, Manfred
T1  - Surgical treatment of vaginal vault prolapse using different prosthetic mesh implants: a finite element analysis
JF  - tm - Technisches Messen
N2  - Particularly multiparous elderly women may suffer from vaginal vault prolapse after hysterectomy due to weak support from lax apical ligaments. A decreased amount of estrogen and progesterone in older age is assumed to remodel the collagen thereby reducing tissue stiffness. Sacrocolpopexy is either performed as open or laparoscopic surgery using prosthetic mesh implants to substitute lax ligaments. Y-shaped mesh models (DynaMesh, Gynemesh, and Ultrapro) are implanted in a 3D female pelvic floor finite element model in the extraperitoneal space from the vaginal cuff to the first sacral (S1) bone below promontory. Numerical simulations are conducted during Valsalva maneuver with weakened tissues modeled by reduced tissue stiffness. Tissues are modeled as incompressible, isotropic hyperelastic materials whereas the meshes are modeled either as orthotropic linear elastic or as isotropic hyperlastic materials. The positions of the vaginal cuff and the bladder base are calculated from the pubococcygeal line for female pelvic floor at rest, for prolapse and after repair using the three meshes. Due to mesh mechanics and mesh pore deformation along the loaded direction, the DynaMesh with regular rectangular mesh pores is found to provide better mechanical support to the organs than the Gynemesh and the Ultrapro with irregular hexagonal mesh pores.

Insbesondere ältere, mehrgebährende Frauen leiden häufiger an einem Scheidenvorfall nach einer Hysterektomie aufgrund der schwachen Unterstützung durch laxe apikale Bänder. Es wird angenommen, dass eine verringerte Menge an Östrogen und Progesteron im höheren Alter das Kollagen umformt, wodurch die Gewebesteifigkeit reduziert wird. Die Sakrokolpopexie ist eine offene oder laparoskopische Operation, die mit prothetischen Netzimplantaten durchgeführt wird, um laxe Bänder zu ersetzen. Y-förmige Netzmodelle (DynaMesh, Gynemesh und Ultrapro) werden in einem 3D-Modell des weiblichen Beckenbodens im extraperitonealen Raum vom Vaginalstumpf bis zum Promontorium implantiert. Numerische Simulationen werden während des Valsalva-Manövers mit geschwächtem Gewebe durchgeführt, das durch eine reduzierte Gewebesteifigkeit modelliert wird. Die Gewebe werden als inkompressible, isotrop hyperelastische Materialien modelliert, während die Netze entweder als orthotrope linear elastische oder als isotrope hyperlastische Materialien modelliert werden. Die Positionen des Vaginalstumpfs, der Blase und der Harnröhrenachse werden anhand der Pubococcygeallinie aus der Ruhelage, für den Prolaps und nach der Reparatur unter Verwendung der drei Netze berechnet. Aufgrund der Netzmechanik und der Netzporenverformung bietet das DynaMesh mit regelmäßigen rechteckigen Netzporen eine bessere mechanische Unterstützung und eine Neupositionierung des Scheidengewölbes, der Blase und der Urethraachse als Gynemesh und Ultrapro mit unregelmäßigen hexagonalen Netzporen.
Y1  - 2018
U6  - http://dx.doi.org/10.1515/teme-2017-0115
SN  - 2196-7113
VL  - 85
IS  - 5
SP  - 331
EP  - 342
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Birgel, Stefan
A1  - Leschinger, Tim
A1  - Wegmann, Kilian
A1  - Staat, Manfred
T1  - Calculation of muscle forces and joint reaction loads in the shoulder area via an OpenSim based computer model
JF  - tm - Technisches Messen
N2  - Using the OpenSim software and verified anatomical data, a computer model for the calculation of biomechanical parameters is developed and used to determine the effect of a reattachment of the Supraspinatus muscle with a medial displacement of the muscle attachment point, which may be necessary for a rupture of the supraspinatus tendon. The results include the influence of the operation on basic biomechanical parameters such as the lever arm, as well as the calculated the muscle activations for the supraspinatus and deltoid. In addition, the influence on joint stability is examined by an analysis of the joint reaction force. The study provides a detailed description of the used model, as well as medical findings to a reattachment of the supraspinatus.

Mit der Software OpenSim und überprüften anatomischen Daten wird ein Computermodell zur Berechnung von biomechanischen Parametern entwickelt und genutzt, um den Effekt einer Refixierung des Supraspinatusmuskels mit einer medialen Verschiebung des Muskelansatzpunktes zu ermitteln, wie sie unter anderem nach einem Riss der Supraspinatussehne notwendig sein kann. Die Ergebnisse umfassen hierbei den Einfluss der Operation auf grundlegende biomechanische Parameter wie den Hebelarm sowie die berechneten Muskelaktivierungen für den Supraspinatus und Deltoideus. Zusätzlich wird der Einfluss auf die Gelenkstabilität betrachtet und durch eine Analyse der Gelenkreaktionskraft untersucht. Die Studie bietet eine detaillierte Beschreibung des genutzten Modells, sowie medizinische Erkenntnisse zu einer Refixierung des Supraspinatus.
Y1  - 2018
U6  - http://dx.doi.org/10.1515/teme-2017-0114
SN  - 2196-7113
VL  - 85
IS  - 5
SP  - 321
EP  - 330
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Bhattarai, Aroj
A1  - Frotscher, Ralf
A1  - Staat, Manfred
T1  - Computational Analysis of Pelvic Floor Dysfunction
T2  - Women's Health and Biomechanics
N2  - Pelvic floor dysfunction (PFD) is characterized by the failure of the levator ani (LA) muscle to maintain the pelvic hiatus, resulting in the descent of the pelvic organs below the pubococcygeal line. This chapter adopts the modified Humphrey material model to consider the effect of the muscle fiber on passive stretching of the LA muscle. The deformation of the LA muscle subjected to intra-abdominal pressure during Valsalva maneuver is compared with the magnetic resonance imaging (MRI) examination of a nulliparous female. Numerical result shows that the fiber-based Humphrey model simulates the muscle behavior better than isotropic constitutive models. Greater posterior movement of the LA muscle widens the levator hiatus due to lack of support from the anococcygeal ligament and the perineal structure as a consequence of birth-related injury and aging. Old and multiparous females with uncontrolled urogenital and rectal hiatus tend to develop PFDs such as prolapse and incontinence.
KW  - Pelvic muscle
KW  - Muscle fibers
KW  - Passive stretching
KW  - Pelvic floor dysfunction
Y1  - 2018
SN  - 978-3-319-71574-2
U6  - http://dx.doi.org/10.1007/978-3-319-71574-2_17
N1  - Lecture Notes in Computational Vision and Biomechanics, vol 29
SP  - 217
EP  - 230
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Bhattarai, Aroj
A1  - Staat, Manfred
T1  - Modelling of Soft Connective Tissues to Investigate Female Pelvic Floor Dysfunctions
JF  - Computational and Mathematical Methods in Medicine
N2  - After menopause, decreased levels of estrogen and progesterone remodel the collagen of the soft tissues thereby reducing their stiffness. Stress urinary incontinence is associated with involuntary urine leakage due to pathological movement of the pelvic organs resulting from lax suspension system, fasciae, and ligaments. This study compares the changes in the orientation and position of the female pelvic organs due to weakened fasciae, ligaments, and their combined laxity. A mixture theory weighted by respective volume fraction of elastin-collagen fibre compound (5%), adipose tissue (85%), and smooth muscle (5%) is adopted to characterize the mechanical behaviour of the fascia. The load carrying response (other than the functional response to the pelvic organs) of each fascia component, pelvic organs, muscles, and ligaments are assumed to be isotropic, hyperelastic, and incompressible. Finite element simulations are conducted during Valsalva manoeuvre with weakened tissues modelled by reduced tissue stiffness. A significant dislocation of the urethrovesical junction is observed due to weakness of the fascia (13.89 mm) compared to the ligaments (5.47 mm). The dynamics of the pelvic floor observed in this study during Valsalva manoeuvre is associated with urethral-bladder hypermobility, greater levator plate angulation, and positive Q-tip test which are observed in incontinent females.
Y1  - 2018
U6  - http://dx.doi.org/10.1155/2018/9518076
SN  - 1748-6718
VL  - 2018
IS  - Article ID 9518076
SP  - 1
EP  - 16
PB  - Hindawi
CY  - New York, NY
ER  -