TY  - JOUR
A1  - Sawada, Kazuaki
A1  - Nakazawa, Hirokazu
A1  - Takenaga, Shoko
A1  - Hizawa, Takeshi
A1  - Futagawa, Masato
A1  - Dasai, Fumihiro
A1  - Sakurai, Takashi
A1  - Okumura, Koichi
A1  - Hattori, Toshiaki
A1  - Ishida, Makoto
T1  - Multimodal bioimage sensor
JF  - IEICE transactions on fundamentals of electronics, communidations and computer sciences
N2  - To visualize the biochemical distribution two-dimensionally, we invented a solid-state-type ion image sensor that indicates the chemical activity of solutions and cells. The device, which consists of a CCD array covered with a functionalized membrane to detect charge accumulation, is highly sensitive to changes in the concentration and two-dimensional distribution of ions and biomaterials.
Y1  - 2014
U6  - http://dx.doi.org/10.1587/transfun.E97.A.726
SN  - 0916-8508 (Print) ; 1745-1337 (Online)
VL  - E97-A (2014)
IS  - 3
SP  - 726
EP  - 733
PB  - IEICE
CY  - Tokyo
ER  - 
TY  - JOUR
A1  - Werner, Frederik
A1  - Takenaga, Shoko
A1  - Taki, Hidenori
A1  - Sawada, Kazuaki
A1  - Schöning, Michael Josef
T1  - Comparison of label-free ACh-imaging sensors based on CCD and LAPS
JF  - Sensors and  Actuators B: Chemical (2012)
N2  - Semiconductor-based chemical imaging sensors, like the light-addressable potentiometric sensor (LAPS) or the pH-imaging sensor based on a charge-coupled device (CCD), are becoming a powerful tool for label-free imaging of biological phenomena. We have proposed a polyion-based enzymatic membrane to develop an acetylcholine (ACh) imaging sensor for neural cell-activity observations. In this study, a CCD-type ACh-imaging sensor and a LAPS-type ACh-imaging sensor were fabricated and the prospect of both sensors was clarified by making a comparison of their basic characteristics.
Y1  - 2013
SN  - 0925-4005
VL  - 177
SP  - 745
EP  - 752
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Takenaga, Shoko
A1  - Werner, Frederik
A1  - Sawada, Kazuaki
A1  - Schöning, Michael Josef
T1  - Comparison of label-free ACh image sensors based on CCD and LAPS
Y1  - 2012
SN  - 978-3-9813484-2-2
U6  - http://dx.doi.org/10.5162/IMCS2012/4.2.6
SP  - 356
EP  - 359
ER  -