TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Larue, H.
A1  - Zimmermann, E.
A1  - Ziemons, Karl
A1  - Halling, H.
T1  - Pulse recording by free-running sampling
JF  - 2000 IEEE Nuclear Science Symposium Conference Record, Vol. 2
N2  - Pulses from a position-sensitive photomultiplier (PS-PMT) are recorded by free running ADCs at a sampling rate of 40 MHz. A four-channel acquisition-board has been developed which is equipped with four 12 bit-ADCs connected to one FPGA (field programmable gate array). The FPGA manages data acquisition and the transfer to the host computer. It can also work as a digital trigger, so a separate hardware-trigger can be omitted. The method of free running sampling provides a maximum of information, besides the pulse charge and amplitude also pulse shape and starting time are contained in the sampled data. These informations are crucial for many tasks such as distinguishing between different scintillator materials, determination of radiation type, pile-up recovery, coincidence detection or time-of-flight applications. The absence of an analog integrator allows coping with very high count rates. Since this method is going to be employed in positron emission tomography (PET), the position of an event is another important information. The simultaneous readout of four channels allows localization by means of center-of-gravity weighting. First results from a test setup with LSO-scintillators coupled to the PS-PMT are presented
Y1  - 2000
SN  - 1082-3654
SP  - 9/179
EP  - 9/181
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Larue, H.
A1  - Zimmermann, E.
A1  - Ziemons, Karl
A1  - Halling, H.
T1  - Pulse recording by free-running sampling
JF  - IEEE Transactions on Nuclear Science
N2  - Pulses from a position-sensitive photomultiplier (PS-PMT) are recorded by free-running ADCs at a sampling rate of 40 MHz. A four-channel acquisition board has been developed which is equipped with four 12-bit ADCs connected to one field programmable gate array (FPGA). The FPGA manages data acquisition and the transfer to the host computer. It can also work as a digital trigger, so a separate hardware trigger can be omitted. The method of free-running sampling provides a maximum of information, besides the pulse charge and amplitude also pulse shape and starting time are contained in the sampled data. This information is crucial for many tasks such as distinguishing between different scintillator materials, determination of radiation type, pile-up recovery, coincidence detection or time-of-flight applications. The absence of an analog integrator allows very high count rates to be dealt with. Since this method is to be employed in positron emission tomography (PET), the position of an event is also important. The simultaneous readout of four channels allows localization by means of center-of-gravity weighting. First results from a test setup with LSO scintillators coupled to the PS-PMT are presented here
Y1  - 2001
SN  - 0018-9499
VL  - 48
IS  - 3
SP  - 524
EP  - 526
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Larue, H.
A1  - Zimmermann, E.
A1  - Ziemons, Karl
A1  - Halling, H.
T1  - A PET system with free running ADCs
JF  - Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
N2  - A small PET system has been built up with two multichannel photomultipliers, which are attached to a matrix of 64 single LSO crystals each. The signal from each multiplier is being sampled continuously by a 12 bit ADC at a sampling frequency of 40 MHz. In case of a scintillation pulse a subsequent FPGA sends the corresponding set of samples together with the channel information and a time mark to the host computer. The data transfer is performed with a rate of 20 MB/s. On the host all necessary information is extracted from the data. The pulse energy is determined, coincident events are detected and multiple hits within one matrix can be identified. In order to achieve a narrow time window the pulse starting time is refined further than the resolution of the time mark (=25 ns) would allow. This is possible by interpolating between the pulse samples. First data obtained from this system will be presented. The system is part of developments for a much larger system and has been created to study the feasibility and performance of the technique and the hardware architecture.
Y1  - 2002
SN  - 0168-9002
N1  - Proceedings of the 6th International Conference on Inorganic Scin tillators and their Use in Scientific and Industrial Applications
VL  - 486
IS  - 1-2
SP  - 18
EP  - 21
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Larue, H.
A1  - Zimmermann, E.
A1  - Ziemons, Karl
A1  - Halling, H.
T1  - Coincidence detection by digital processing of free-running sampled pulses
JF  - Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
N2  - Coincident events in two scintillator crystals coupled to photomultipliers (PMT) are detected by processing just the digital data of the recorded pulses. For this purpose the signals from both PMTs are continuously sampled by free-running ADCs at a sampling rate of 40 MHz. For each sampled pulse the starting time is determined by processing the pulse data. Even a fairly simple interpolating algorithm results in a FWHM of about 2 ns.
Y1  - 2002
SN  - 0168-9002
VL  - 487
IS  - 3
SP  - 530
EP  - 534
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Larue, H.
A1  - Zimmermann, E.
A1  - Ziemons, Karl
A1  - Halling, H.
T1  - A PET system based on data processing of free-running sampled pulses
JF  - 2001 IEEE Nuclear Science Symposium Conference Record, Vol. 2
N2  - Within the developments for the Crystal Clear small animal PET project (CLEARPET) a dual head PET system has been established. The basic principle is the early digitization of the detector pulses by free running ADCs. The determination of the γ-energy and also the coincidence detection is performed by data processing of the sampled pulses on the host computer. Therefore a time mark is attached to each pulse identifying the current cycle of the 40 MHz sampling clock. In order to refine the time resolution the pulse starting time is interpolated from the samples of the pulse rise. The detector heads consist of multichannel PMTs with a single LSO scintillator crystal coupled to each channel. For each PMT only one ADC is required. The position of an event is obtained separately from trigger signals generated for each single channel. An FPGA is utilized for pulse buffering, generation of the time mark and for the data transfer to the host via a fast I/O-interface.
Y1  - 2002
SN  - 1082-3654
SP  - 693
EP  - 694
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Larue, H.
A1  - Saleh, H.
A1  - Zimmermann, E.
A1  - Ziemons, Karl
A1  - Halling, H.
T1  - Pulse shape discrimination of LSO and LuYAP scintillators for depth of interaction detection in PET
JF  - 2002 IEEE Nuclear Science Symposium Conference Record, Vol. 3
N2  - A feasible way to gain the depth of interaction information in a PET scanner is the use of phoswich detectors. In general the layer of interaction is identified front the pulse shape of the corresponding scintillator material. In this work pulses from LSO and LuYAP crystals were investigated in order to find a practical method of distinguishing. It turned out that such a pulse processing could he kept simple due to an additional slow component in the light decay of the LuYAP pulse. At the same time the short decay time guarantees that the major amount of the light output is still collected within a short pulse recording time.
Y1  - 2003
SN  - 1082-3654
SP  - 1636
EP  - 1639
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Larue, H.
A1  - Saleh, H.
A1  - Zimmermann, E.
A1  - Ziemons, Karl
A1  - Halling, H.
T1  - Pulse shape discrimination of LSO and LuYAP scintillators for depth of interaction detection in PET
JF  - IEEE Transactions on Nuclear Science
N2  - A feasible way to gain the depth of interaction information in a positron emission tomography scanner is the use of phoswich detectors. In general, the layer of interaction is identified from the pulse shape of the corresponding scintillator material. In this work, pulses from LSO and LuYAP crystals were investigated in order to find a practical method of distinguishing. It turned out that such a pulse processing could be kept simple because of an additional slow component in the light decay of the LuYAP pulse. At the same time, the short decay time guarantees that the major amount of the light output is still collected within a short pulse recording time.
Y1  - 2003
SN  - 0018-9499
VL  - 50
IS  - 3
SP  - 344
EP  - 347
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Larue, H.
A1  - Parl, C.
A1  - Ziemons, Karl
T1  - The data acquisition system of ClearPET neuro - a small animal PET scanner
JF  - IEEE Transactions on Nuclear Science
N2  - The Crystal Clear Collaboration has developed a modular system for a small animal PET scanner (ClearPET). The modularity allows the assembly of scanners of different sizes and characteristics in order to satisfy the specific needs of the individual member institutions. The system performs depth of interaction detection by using a phoswich arrangement combining LSO and LuYAP scintillators which are coupled to Multichannel Photomultipliers (PMTs). For each PMT a free running 40 MHz ADC digitizes the signal and the complete scintillation pulse is sampled by an FPGA and sent with 20 MB/s to a PC for preprocessing. The pulse provides information about the gamma energy and the scintillator material which identifies the interaction layer. Furthermore, the exact pulse starting time is obtained from the sampled data. This is important as no hardware coincidence detection is implemented. All single events are recorded and coincidences are identified by software. The system in Jülich (ClearPET Neuro) is equipped with 10240 crystals on 80 PMTs. The paper will present an overview of the data acquisition system.
Y1  - 2006
SN  - 0018-9499
VL  - 53
IS  - 3
SP  - 700
EP  - 703
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Khodaverdi, M.
A1  - Larue, H.
A1  - Parl, C.
A1  - Ziemons, Karl
T1  - Timemark correction for the ClearPET™ scanners
JF  - 2005 IEEE Nuclear Science Symposium Conference Record, Vol. 4
N2  - The small animal PET scanners developed by the Crystal Clear Collaboration (ClearPETtrade) detect coincidences by analyzing timemarks which are attached to each event. The scanners are able to save complete single list mode data which allows analysis and modification of the timemarks after data acquisition. The timemarks are obtained from the digitally sampled detector pulses by calculating the baseline crossing of the rising edge of the pulse which is approximated as a straight line. But the limited sampling frequency causes a systematic error in the determination of the timemark. This error depends on the phase of the sampling clock at the time of the event. A statistical method that corrects these errors will be presented
Y1  - 2006
SN  - 1082-3654
SP  - 2057
EP  - 2060
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Brandenburg, G.
A1  - Brökel, M.
A1  - Fuss, L.
A1  - Larue, H.
A1  - Parl, C.
A1  - Zimmermann, E.
A1  - Ziemons, Karl
A1  - Halling, H.
T1  - The ClearPET data acquisition
JF  - 2003 IEEE Nuclear Science Symposium Conference Record, Vol. 5
N2  - Within the Crystal Clear Collaboration a modular system for a small animal PET scanner (ClearPET™) has been developed. The modularity allows the assembly of scanners of different sizes and characteristics in order to fit the specific needs of the individual member institutions. Now a first demonstrator is being completed in Julich. The system performs depth of interaction detection by using a phoswich arrangement combining LSO and LuYAP scintillators which are coupled to multi-channel photomultipliers (PMTs). A free-running ADC digitizes the signal from the PMT and the complete scintillation pulses are sampled by an FPGA and sent with 20 MB/S to a PC for preprocessing. The pulse provides information about the gamma energy and the scintillator material which identifies the interaction layer. Furthermore, the exact pulse starting time is obtained from the sampled data. This is important as no hardware coincidence detection is implemented. All single events are recorded and coincidences are identified by software. An advantage of that is that the coincidence window and the dimensions of the field of view can be adjusted easily. The ClearPET™ demonstrator is equipped with 10240 crystals on 80 PMTs. This paper presents an overview of the data acquisition system.
Y1  - 2004
SN  - 1082-3654
SP  - 3097
EP  - 3100
ER  - 
TY  - JOUR
A1  - Streun, M.
A1  - Beer, S.
A1  - Hombach, T.
A1  - Jahnke, S.
A1  - Khodaverdi, M.
A1  - Larue, H.
A1  - Minwuyelet, S.
A1  - Parl, C.
A1  - Roeb, G.
A1  - Schurr, U.
A1  - Ziemons, Karl
T1  - PlanTIS: A positron emission tomograph for imaging 11C transport in plants
JF  - 2007 IEEE Nuclear Science Symposium Conference Record, Vol. 6
N2  - Plant growth and transport processes are highly dynamic. They are characterized by plant-internal control processes and by strong interactions with the spatially and temporally varying environment. Analysis of structure- function relations of growth and transport in plants will strongly benefit from the development of non-invasive techniques. PlanTIS (Plant Tomographic Imaging System) is designed for non-destructive 3D-imaging of positron emitting radiotracers. It will permit functional analysis of the dynamics of carbon distribution in plants including bulky organs. It will be applicable for screening transport properties of plants to evaluate e.g. temperature adaptation of genetically modified plants. PlanTIS is a PET scanner dedicated to monitor the dynamics of the 11C distribution within a plant while or after assimilation of 11CO2. Front end electronics and data acquisition architecture of the scanner are based on the ClearPETTM system [1]. Four detector modules form one of two opposing detector blocks. Optionally, a hardware coincidence detection between the blocks can be applied. In general the scan duration is rather long (~ 1 hour) compared to the decay time of 11C (20 min). As a result the count rates can vary over a wide range and accurate dead time correction is necessary.
Y1  - 2008
SN  - 1082-3654
SP  - 4110
EP  - 4112
ER  - 
TY  - CHAP
A1  - Streun, M.
A1  - Al-Kaddoum, R.
A1  - Parl, C.
A1  - Pietrzyk, U.
A1  - Ziemons, Karl
A1  - Waasen, S. van
T1  - Simulation studies of optical photons in monolithic block scintillators
T2  - 2011 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)
N2  - The interest in PET detectors with monolithic block scintillators is growing. In order to obtain high spatial resolutions dedicated positioning algorithms are required. But even an ideal algorithm can only deliver information which is provided by the detector. In this simulation study we investigated the light distribution on one surface of cuboid LSO scintillators of different size. Scintillators with a large aspect ratio (small footprint and large height) showed significant position information only for a minimum interaction depth of the gamma particle. The results allow a quantitative estimate for a useful aspect ratio.
Y1  - 2012
SN  - 978-1-4673-0120-6 (electronic ISBN)
SN  - 978-1-4673-0118-3 (print ISBN)
U6  - http://dx.doi.org/10.1109/NSSMIC.2011.6154621
SP  - 1380
EP  - 1382
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Streese, Lukas
A1  - Kotliar, Konstantin
A1  - Deiseroth, Arne
A1  - Infanger, Denis
A1  - Gugleta, Konstantin
A1  - Schmaderer, Christoph
A1  - Hanssen, Henner
T1  - Retinal endothelial function in cardiovascular risk patients: A randomized controlled exercise trial
JF  - Scandinavian Journal of Medicine and Science in Sports
N2  - The aim of this study was to investigate, for the first time, the effects of high-intensity interval training (HIIT) on retinal microvascular endothelial function in cardiovascular (CV) risk patients. In the randomized controlled trial, middle-aged and previously sedentary patients with increased CV risk (aged 58 ± 6 years) with ≥ two CV risk factors were randomized into a 12-week HIIT (n = 33) or control group (CG, n = 36) with standard physical activity recommendations. A blinded examiner measured retinal endothelial function by flicker light-induced maximal arteriolar (ADmax) and venular (VDmax) dilatation as well as the area under the arteriolar (AFarea) and venular (VFarea) flicker curve using a retinal vessel analyzer. Standardized assessments of CV risk factors, cardiorespiratory fitness, and retinal endothelial function were performed before and after HIIT. HIIT reduced body mass index, fat mass, and low-density lipoprotein and increased muscle mass and peak oxygen uptake (VO2peak). Both ADmax (pre: 2.7 ± 2.1%, post: 3.0 ± 2.2%, P = .018) and AFarea (pre: 32.6 ± 28.4%*s, post: 37.7 ± 30.6%*s, P = .016) increased after HIIT compared with CG (ADmax, pre: 3.2 ± 1.8%, post: 2.9 ± 1.8%, P = .254; AFarea, pre: 41.6 ± 28.5%*s, post: 37.8 ± 27.0%*s, P = .186). Venular function remained unchanged after HIIT. There was a significant association between ∆-change VO2peak and ∆-changes ADmax and AFarea (P = .026, R² = 0.073; P = .019, R² = 0.081, respectively). 12-weeks of HIIT improved retinal endothelial function in middle-aged patients with increased CV risk independent of the reduction in classical CV risk factors. Exercise has the potential to reverse or at least postpone progression of small vessel disease in older adults with increased CV risk under standard medication. Dynamic retinal vessel analysis seems to be a sensitive tool to detect treatment effects of exercise interventions on retinal microvascular endothelial function in middle-aged individuals with increased CV risk.
Y1  - 2020
U6  - http://dx.doi.org/10.1111/sms.13560
SN  - 1600-0838
VL  - 30
IS  - 2
SP  - 272
EP  - 280
PB  - Wiley
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Steinseifer, Ulrich
A1  - Kashefi, Ali
A1  - Hormes, Marcus
A1  - Schoberer, Mark
A1  - Orlikowsky, Thorsten
A1  - Behbahani, Mehdi
A1  - Behr, Marek
A1  - Schmitz-Rode, Thomas
T1  - Miniaturization of ECMO Systems : Engineering Challenges and Methods
JF  - Artificial Organs. 33 (2009), H. 5
Y1  - 2009
SN  - 1525-1594
N1  - Fifth International Conference on Pediatric Mechanical Circulatory Support Systems and Pediatric Cardiopulmonary Perfusion Abstracts <May 28, 2009>
SP  - A55
EP  - A55
ER  - 
TY  - JOUR
A1  - Stadler, Andreas M.
A1  - Zerlin, Kay
A1  - Digel, Ilya
A1  - Büldt, Georg
A1  - Zaccai, Guiseppe
A1  - Artmann, Gerhard
T1  - Dynamics and interactions of hemoglobin in red blood cells
JF  - Tissue Engineering Part A. 14 (2008), H. 5
Y1  - 2008
SN  - 1937-3341
N1  - TERMIS EU 2008 Porto Meeting June 22–26, 2008 Porto Congress Center–Alfândega Portugal
SP  - 724
EP  - 724
ER  - 
TY  - JOUR
A1  - Stadler, Andreas M.
A1  - Garvey, G. J.
A1  - Bocahut, A.
A1  - Sacquin-Mora, S.
A1  - Digel, Ilya
A1  - Schneider, G. J.
A1  - Natali, F.
A1  - Artmann, Gerhard
A1  - Zaccai, G.
T1  - Thermal fluctuations of haemoglobin from different species : adaptation to temperature via conformational dynamics
JF  - Journal of the Royal Society Interface
N2  - Thermodynamic stability, configurational motions and internal forces of haemoglobin (Hb) of three endotherms (platypus, Ornithorhynchus anatinus; domestic chicken, Gallus gallus domesticus and human, Homo sapiens) and an ectotherm (salt water crocodile, Crocodylus porosus) were investigated using circular dichroism, incoherent elastic neutron scattering and coarse-grained Brownian dynamics simulations. The experimental results from Hb solutions revealed a direct correlation between protein resilience, melting temperature and average body temperature of the different species on the 0.1 ns time scale. Molecular forces appeared to be adapted to permit conformational fluctuations with a root mean square displacement close to 1.2 Å at the corresponding average body temperature of the endotherms. Strong forces within crocodile Hb maintain the amplitudes of motion within a narrow limit over the entire temperature range in which the animal lives. In fully hydrated powder samples of human and chicken, Hb mean square displacements and effective force constants on the 1 ns time scale showed no differences over the whole temperature range from 10 to 300 K, in contrast to the solution case. A complementary result of the study, therefore, is that one hydration layer is not sufficient to activate all conformational fluctuations of Hb in the pico- to nanosecond time scale which might be relevant for biological function. Coarse-grained Brownian dynamics simulations permitted to explore residue-specific effects. They indicated that temperature sensing of human and chicken Hb occurs mainly at residues lining internal cavities in the β-subunits.
Y1  - 2012
U6  - http://dx.doi.org/10.1098/rsif.2012.0364
SN  - 1742-5689
VL  - 9
IS  - 76
SP  - 2845
EP  - 2855
PB  - The Royal Society
CY  - London
ER  - 
TY  - JOUR
A1  - Stadler, Andreas M.
A1  - Embs, Jan P.
A1  - Digel, Ilya
A1  - Artmann, Gerhard
A1  - Unruh, Tobias
A1  - Büldt, Georg
A1  - Zaccai, Guiseppe
T1  - Cytoplasmic water and hydration layer dynamics in human red blood cells
JF  - Journal of the American Chemical Society. 50 (2008), H. 130
Y1  - 2008
SN  - 1520-5126
SP  - 16852
EP  - 16853
ER  - 
TY  - JOUR
A1  - Stadler, Andreas M.
A1  - Digel, Ilya
A1  - Embs, Jan P.
A1  - Unruh, Tobias
A1  - Tehei, M.
A1  - Zaccai, G.
A1  - Büldt, G.
A1  - Artmann, Gerhard
T1  - From powder to solution : Hydration dependence of human hemoglobin dynamics correlated to body temperature
JF  - Biophysical Journal. 96 (2009), H. 12
Y1  - 2009
SN  - 0006-3495
SP  - 5073
EP  - 5081
PB  - Cell Press
CY  - Cambridge, Mass.
ER  - 
TY  - JOUR
A1  - Stadler, A.  M.
A1  - Digel, Ilya
A1  - Artmann, Gerhard
A1  - Embs, Jan P.
A1  - Zaccai, Joe
A1  - Büldt, Georg
T1  - Hemoglobin Dynamics in Red Blood Cells: Correlation to Body Temperature
JF  - Biophysical Journal. 95 (2008), H. 11
Y1  - 2008
SN  - 1542-0086
SP  - 5449
EP  - 5461
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Khoi Duc
T1  - Limit loads of circumferentially flawed pipes and cylindrical vessels under internal pressure
JF  - International Journal of Pressure Vessels and Piping. 83 (2006), H. 3
Y1  - 2006
SN  - 0308-0161
SP  - 188
EP  - 196
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Duc-Khoi
T1  - An Algorithm for Shakedown Analysis for Materials with Temperature Dependent Yield Stress
JF  - Proceedings in Applied Mathematics and Mechanics (PAMM). 4 (2004), H. 1
Y1  - 2004
SN  - 1617-7061
SP  - 231
EP  - 233
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Duc-Khoi
T1  - Limit analysis of flaws in pressurized pipes and cylindrical vessels. Part I: Axial defects
JF  - Engineering Fracture Mechanics. 74 (2007), H. 3
Y1  - 2007
SN  - 0013-7944
SP  - 431
EP  - 450
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Vu, Duc Khoi
T1  - Limit analysis of flaws in pressurized pipes and cylindrical vessels Part II: Circumferential defects
JF  - Engineering Fracture Mechanics ; 97(2013), H. 1
N2  - Upper and lower bound theorems of limit analyses have been presented in part I of the paper. Part II starts with the finite element discretization of these theorems and demonstrates how both can be combined in a primal–dual optimization problem. This recently proposed numerical method is used to guide the development of a new class of closed-form limit loads for circumferential defects, which show that only large defects contribute to plastic collapse with a rapid loss of strength with increasing crack sizes. The formulae are compared with primal–dual FEM limit analyses and with burst tests. Even closer predictions are obtained with iterative limit load solutions for the von Mises yield function and for the Tresca yield function. Pressure loading of the faces of interior cracks in thick pipes reduces the collapse load of circumferential defects more than for axial flaws. Axial defects have been treated in part I of the paper.
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.engfracmech.2012.05.017
SN  - 0013-7944
VL  - 97
SP  - 314
EP  - 333
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Trenz, Eva
A1  - Lohmann, Philipp
A1  - Frotscher, Ralf
A1  - Klinge, Uwe
A1  - Tabaza, Ruth
A1  - Kirschner-Hermanns, Ruth
T1  - New measurements to compare soft tissue anchoring systems in pelvic floor surgery
JF  - Journal of Biomedical Materials Research Part B: Applied Biomaterials
N2  - Suburethral slings as well as different meshes are widely used treating stress urinary incontinence and prolaps in women. With the development of MiniSlings and special meshes using less alloplastic material anchorage systems become more important to keep devices in place and to put some tension especially on the MiniSlings. To date, there are many different systems of MiniSlings of different companies on the market which differ in the structure of the used meshes and anchors. A new objective measurement method to compare different properties of MiniSling systems (mesh and anchor) is presented in this article. Ballistic gelatine acts as soft tissue surrogate. Significant differences in parameters like pull-out strength of anchors or shrinkage of meshes under loading conditions have been determined. The form and size of the anchors as well as the structural stability of the meshes are decisive for a proper integration. The tested anchorings sytems showed markedly different mechanical function at their respective load bearing capacity. As the stable fixation of the device in tissue is a prerequisite for a permanet reinforcement, the proposed test system permits further optimisation of anchor and mesh devices to improve the success of the surgical treatment
Y1  - 2012
U6  - http://dx.doi.org/10.1002/jbm.b.32654
SN  - 1552-4981
VL  - 100B
IS  - 4
SP  - 924
EP  - 933
PB  - Wiley
CY  - Hoboken, NJ
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Tran, Thanh Ngoc
A1  - Kreißig, R.
T1  - Load bearing capacity of thin shell structures made of elastoplastic material by direct methods
JF  - Technische Mechanik. 28 (2008), H. 3-4
Y1  - 2008
SP  - 299
EP  - 309
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Tran, Ngoc Trinh
T1  - Strain based brittle failure criteria for rocks
T2  - Proceedings of (NACOME2022) The 11th National Conference on Mechanics, Vol. 1. Solid Mechanics, Rock Mechanics, Artificial Intelligence, Teaching and Training, Hanoi, December 2-3, 2022
N2  - When confining pressure is low or absent, extensional fractures are typical, with fractures occurring on unloaded planes in rock. These “paradox” fractures can be explained by a phenomenological extension strain failure criterion. In the past, a simple empirical criterion for fracture initiation in brittle rock has been developed. But this criterion makes unrealistic strength predictions in biaxial compression and tension. A new extension strain criterion overcomes this limitation by adding a weighted principal shear component. The weight is chosen, such that the enriched extension strain criterion represents the same failure surface as the Mohr–Coulomb (MC) criterion. Thus, the MC criterion has been derived as an extension strain criterion predicting failure modes, which are unexpected in the understanding of the failure of cohesive-frictional materials. In progressive damage of rock, the most likely fracture direction is orthogonal to the maximum extension strain. The enriched extension strain criterion is proposed as a threshold surface for crack initiation CI and crack damage CD and as a failure surface at peak P. Examples show that the enriched extension strain criterion predicts much lower volumes of damaged rock mass compared to the simple extension strain criterion.
KW  - Extension fracture
KW  - Extension strain criterion
KW  - Mohr–Coulomb criterion
KW  - Evolution of damage
Y1  - 2023
SN  - 978-604-357-084-7
SP  - 500
EP  - 509
PB  - Nha xuat ban Khoa hoc tu nhien va Cong nghe (Verlag Naturwissenschaft und Technik)
CY  - Hanoi
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Sponagel, Stefan
A1  - Nguyen, Nhu Huynh
T1  - Experiment and material model for soft tissue materials
JF  - Constitutive  models for rubber VI : proceedings of the sixth European Conference on Constitutive Models for Rubber, Dresden, Germany, 7 - 10 September 2009 / eds. Gert Heinrich ...
Y1  - 2010
SN  - 978-0-415-56327-7
SP  - 465
EP  - 470
PB  - CRC Press
CY  - Boca Raton [u.a.]
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Schwartz, M.
A1  - Lang, H.
A1  - Wirtz, K.
A1  - Heitzer, M.
T1  - Design by Analysis of Pressure Components by non-linear Optimization
JF  - The 10th International Conference on Pressure Vessel Technology, July 7-10, 2003, Vienna, Austria, Proceedings ICPVT-10 / Zeman, J. L. [ed]
Y1  - 2003
SN  - 3950152814
SP  - 59
EP  - 65
PB  - ÖGS, Österreichische Gesellschaft für Schweißtechnik
CY  - Wien
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Heitzer, Michael
ED  - Staat, Manfred
ED  - Heitzer, Michael
T1  - Probabilistic limit and shakedown problems
T2  - Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems
Y1  - 2003
SN  - 3-00-010001-6
N1  - NIC Series
VL  - 15
SP  - 217
EP  - 268
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - BOOK
A1  - Staat, Manfred
A1  - Heitzer, Michael
T1  - Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems.
Y1  - 2003
SN  - 3-00-010001-6
N1  - NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - BOOK
A1  - Staat, Manfred
A1  - Heitzer, M.
A1  - Yan, Ai-Min
A1  - Khoi, Vu Duc
A1  - Nguyen, Dang Hung
A1  - Valdoire, F.
A1  - Lahousse, A.
T1  - Limit Analysis of Defects
Y1  - 2000
SN  - 0944-2952
N1  - Bericht des Forschungszentrums, Jül-3746, Jülich (2000)
PB  - Forschungszentrum Jülich
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
A1  - Reiners, H.
A1  - Schubert, F.
T1  - Shakedown and ratchetting under tension–torsion loadings: analysis and experiments
JF  - Nuclear Engineering and Design. 225 (2003), H. 1
Y1  - 2003
SN  - 0029-5493
SP  - 11
EP  - 26
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
A1  - Lang, H.
A1  - Wirtz, K.
T1  - Direct Finite Element Route for Design-by-Analysis of Pressure Components
JF  - International Journal of Pressure Vessels and Piping. 82 (2005), H. 1
Y1  - 2005
SN  - 0308-0161
SP  - 61
EP  - 67
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Limit and Shakedown Analysis for Plastic Safety of Complex Structures
JF  - Transactions of the 14th International Conference on Structural Dynamics in Reactor Technology (SMiRT-14) / Livolant, M. [ed]
Y1  - 1997
N1  - Vol. B, Paper B02/2
SP  - 33
EP  - 40
CY  - Lyon
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Reliability Analysis of Elasto-Plastic Structures under Variable Loads
JF  - Inelastic analysis of structures under variable loads : theory and engineering applications / Maier, G.; Weichert, D. [ed]
Y1  - 2000
SN  - 0-7923-6645-X
SP  - 269
EP  - 288
PB  - Kluwer Academic Publ.
CY  - Dordrecht
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Structural Reliability Analysis of Elasto-Plastic Structures
JF  - Safety and reliability : proceedings of ESREL '99, the Tenth European Conference on Safety and Reliability, Munich-Garching, Germany, 13 - 17 September 1999 / Schuëller, G. I.; Kafka, P. [eds]
Y1  - 1999
SN  - 90-5809-109-0
SP  - 513
EP  - 518
PB  - Balkema
CY  - Rotterdam
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Limit and Shakedown Analysis with Uncertain Data
JF  - Stochastic optimization techniques : numerical methods and technical applications / Marti, K. [ed]
Y1  - 2002
SN  - 3-540-42889-5
SP  - 241
EP  - 254
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Probabilistic limit and shakedown problems
JF  - Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M; Heitzer, M.
Y1  - 2003
SN  - 3-00-010001-6
SP  - 217
EP  - 268
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Basis reduction technique for limit and shakedown problems
T2  - Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M.; Heitzer, M.
Y1  - 2003
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0001-2018112115
SN  - 3-00-010001-6
SP  - 1
EP  - 55
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - FEM-computation of load carrying capacity of highly loaded passive components by direct methods. Heitzer, M. ; Staat, M.
JF  - Nuclear Engineering and Design. 193 (1999), H. 3
Y1  - 1999
SN  - 0029-5493
SP  - 349
EP  - 358
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Fiorini, G. L.
A1  - Lensa, W. von
A1  - Burgazzi, L.
T1  - Reliability Methods for Passive Safety Functions
JF  - Proceedings of the SMiRT 14 Post Conference Seminar No 18 on Passive Safety Features in Nuclear Installations
Y1  - 1997
CY  - Pisa
ER  - 
TY  - BOOK
A1  - Staat, Manfred
A1  - Erni, Daniel
T1  - Symposium Proceedings; 3rd YRA MedTech Symposium 2019: May 24 / 2019 / FH Aachen
Y1  - 2019
SN  - 978-3-940402-22-6
U6  - http://dx.doi.org/10.17185/duepublico/48750
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - BOOK
A1  - Staat, Manfred
A1  - Digel, Ilya
A1  - Trzewik, Jürgen
A1  - Sielemann, Stefanie
A1  - Erni, Daniel
A1  - Zylka, Waldemar
T1  - Symposium Proceedings; 4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen
Y1  - 2024
SN  - 978-3-940402-65-3
U6  - http://dx.doi.org/10.17185/duepublico/81475
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Baroud, G.
A1  - Topcu, M.
A1  - Sponagel, Stefan
T1  - Soft Materials in Technology and Biology – Characteristics, Properties, and Parameter Identification
JF  - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.)
Y1  - 2008
SN  - 978-3-540-75408-4
SP  - 253
EP  - 315
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Ballmann, J.
T1  - Wave Propagation and Focussing in Plates
JF  - Impact loading and dynamic behaviour of materials : Papers presented at the International Conference on Impact Loading and Dynamic Behaviour of Materials, Vol. 2 /  Chiem, C. Y.; Kunze, L. (u.a.) [eds]
Y1  - 1988
PB  - DGM Informationsges.
CY  - Oberursel
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Problems and Chances for Probabilistic Fracture Mechanics in the Analysis of Steel Pressure Boundary Reliability
JF  - Technical feasibility and reliability of passive safety systems for nuclear power plants. Proceedings of an Advisory Group Meeting held in Jülich, 21-24 November 1994
Y1  - 1996
N1  - IAEA-TECDOC-920 ; Onlinezugriff erfolgt auf die überarb. Ausg. 2006
SP  - 43
EP  - 55
CY  - Vienna
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Sensitivity of and Influences on the Reliability of an HTR-Module Primary Circuit Pressure Boundary
JF  - Transactions of the 12th International Conference on Structural Mechanics in Reactor Technology (SMiRT-12) / Kussmaul, K. [ed]
Y1  - 1993
SN  - 0-444-81515-5
N1  - Vol. M, Paper MG10/2
SP  - 147
EP  - 152
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Reliability of the Primary Circuit Pressure Boundary of an HTR-Module under Accident Conditions
JF  - Safety and reliability assessment : an integral approach ; ESREL'93 ; proceedings of the European Safety and Reliability Conference, Munich, Germany, May 10th - 12th 1993 / Kafka, P. [ed]
Y1  - 1993
SN  - 0-444-81561-9
SP  - 331
EP  - 342
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Some Achievements of the European Project LISA for FEM Based Limit and Shakedown Analysis
JF  - Computational mechanics : developments and applications, 2002 : presented at the 2002 ASME Pressure Vessels and Piping Conference, Vancouver, British Columbia, Canada, August 5 - 9. / Badie, N. [ed]
Y1  - 2002
SN  - 0791846520
N1  - Serie PVP ; vol. 441.
SP  - 177
EP  - 185
PB  - American Society of Mechanical Engineers
CY  - New York
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Plastic collapse analysis of longitudinally flawed pipes and vessels
JF  - Nuclear Engineering and Design. 234 (2004), H. 1-3
Y1  - 2004
SN  - 0029-5493
SP  - 25
EP  - 43
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Local and global collapse pressure of longitudinally flawed pipes and cylindrical vessels
JF  - International Journal of Pressure Vessels and Piping. 82 (2005), H. 3
Y1  - 2005
SN  - 0308-0161
SP  - 217
EP  - 225
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Failure probabilities of the primary circuit pressure boundary of an HTR-Module for process heat generation under accident conditions for different failure modes
JF  - Nuclear Engineering and Design. 144 (1993), H. 1
Y1  - 1993
SN  - 0029-5493
SP  - 53
EP  - 67
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Reliability of an HTR-module primary circuit pressure boundary Influences, sensitivity, and comparison with a PWR
JF  - Nuclear Engineering and Design. 158 (1995), H. 2-3
Y1  - 1995
SN  - 0029-5493
SP  - 333
EP  - 340
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Probabilistic assessment of the fracture mechanics behaviour of an HTR-module primary circuit pressure boundary
JF  - Nuclear Engineering and Design. 160 (1996), H. 1-2
Y1  - 1996
SN  - 0029-5493
SP  - 221
EP  - 236
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Limit and shakedown analysis under uncertainty
JF  - International journal of computational methods : IJCM
Y1  - 2013
SN  - 0219-8762
SP  - Publ. online
PB  - World Scientific Publishing
CY  - Singapore
ER  - 
TY  - JOUR
A1  - Staat, Manfred
T1  - Limit and shakedown analysis under uncertainty
JF  - Tap chi Khoa hoc & ung dung - Dai hoc Ton Duc Thang
Y1  - 2012
N1  - = Journal of Applied Sciences - Ton Duc Thang University
VL  - 19
SP  - 45
EP  - 47
ER  - 
TY  - PAT
A1  - Sponagel, Stefan
A1  - Wachowitz, Waldemar
T1  - Shaft seal : United States Patent 5,143,385 ; date of patent: Sep. 1, 1992 / assignee: Firma Carl Freudenberg
Y1  - 1992
N1  - Barcode: US005143385A ; Volltext über Datenbank: http://www.google.com/patents
PB  - [United States Patent and Trademark Office]
CY  - [Alexandria, VA]
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Kilthau, G.
A1  - Spies, K. H.
T1  - Sealing mechanism of lip seals
JF  - Eleventh 11th International Conference on Fluid Sealing : proceedings of the 11th Internat. Conference on Fluid Sealing, held at Cannes, France 8 - 10 April, 1987 / organised and sponsored by BHRA, the Fluid Engineering Centre. Ed. B. S. Nau
Y1  - 1987
SN  - 3-540-51383-3
N1  - International Conference on Fluid Sealing <11, 1987, Cannes>
SP  - 748
EP  - 772
PB  - Elsevier
CY  - London
ER  - 
TY  - PAT
A1  - Sponagel, Stefan
A1  - Graf, Günter
A1  - Groß, Heinz
T1  - Method for manufacturing a sealing ring : United States Patent 4,861,536 ; date of patent: Aug. 12, 1989 / assignee: Firma Carl Freudenberg. Inventors: Gunter Graf ; Heinz Gross ; Stefan Sponagel
Y1  - 1989
N1  - Barcode: US004861536A ; Volltext über Datenbank: http://www.google.com/patents
PB  - [United States Patent and Trademark Office]
CY  - [Alexandria, VA]
ER  - 
TY  - PAT
A1  - Sponagel, Stefan
A1  - Graf, Günter
A1  - Groß, Heinz
T1  - Method for the manufacture of a sealing ring with a sealing lip having hydrodynamically acting return elements : United States Patent 4,850,097 ; date of patent: Jul. 25, 1989 / assignee: Firma Carl Freudenberg. Inventors: Gunter Graf ; Heinz Gross ; Stefan Sponagel
Y1  - 1989
N1  - Barcode: US004850097A ; Volltext über Datenbank: http://www.google.com/patents
PB  - [United States Patent and Trademark Office]
CY  - [Alexandria, VA]
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Baroud, G.
A1  - Steffen, T.
A1  - Wu, J.
T1  - Parameter identification for cement infiltration of osteoporotic bone
JF  - Poromechanics II : Proceedings of the Second Biot Conference on Poromechanics Grenoble, France 26 - 28 August 2002 / ed. by J.-L. Auriault ...
Y1  - 2002
SN  - 90-5809-394-8
SP  - 55
EP  - 58
PB  - Balkema
CY  - Lisse [u.a.]
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Baroud, G.
A1  - Falk, R.
A1  - Crookshank, M.
T1  - Experimental and theoretical investigation of directional permeability of human vertebral cancellous bone for cement infiltration. G. Baroud, R. Falk, M. Crookshank, S. Sponagel, T. Steffen
JF  - Journal of Biomechanics. 37 (2004), H. 2
Y1  - 2004
SN  - 0021-9290
SP  - 189
EP  - 196
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Baroud, G.
A1  - Falk, R.
A1  - Crookshank, M.
T1  - Corrigendum to “Experimental and theoretical investigation of directional permeability of human vertebral cancellous bone for cement infiltration”. Baroud, G.; Falk, R.; Crookshank, M.; Sponagel, S.; Steffen, T.
JF  - Journal of Biomechanics. 37 (2004), H. 2
Y1  - 2004
SN  - 0021-9290
SP  - 1802
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Akbay, U.
A1  - Becker, E.
A1  - Krozer, S.
T1  - Instability of slow viscometric flow
JF  - Mechanics Research Communications. 7 (1980), H. 4
Y1  - 1980
SN  - 0093-6413
SP  - 199
EP  - 204
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Akbay, U.
A1  - Becker, E.
T1  - Instability of plane Couette flow of viscoelastic liquids
JF  - Journal of non-Newtonian fluid mechanics. 18 (1985), H. 2
Y1  - 1985
SN  - 0377-0257
SP  - 123
EP  - 141
ER  - 
TY  - JOUR
A1  - Sponagel, Stefan
A1  - Adbay, U.
A1  - Becker, E.
A1  - Krozer, S.
T1  - A possible cause of viscoelastic turbulence
JF  - Rheology : proceedings of the 8th International Congress of Rheology, held in Naples, Italy, September 1 - 5, 1980 / Hrsg. von Giovanni Astarita, Vol. 2
Y1  - 1980
SN  - 0-306-40465-6
SP  - 79
EP  - 84
PB  - Plenum Pr.
CY  - New York
ER  - 
TY  - JOUR
A1  - Spelthahn, Heiko
A1  - Schubert, Jürgen
A1  - Schöning, Michael Josef
T1  - Dünnschichtsensoren für die Schwermetallanalytik
JF  - GIT : Labor-Fachzeitschrift
N2  - Die Detektion von Schadstoffen repräsentiert in der Umweltanalytik eine wichtige Aufgabenstellung. Gerade die Abwasser- bzw. Brauchwasseranalytik sowie die Prozesskontrolle haben einen hohen Stellenwert. Siliziumbasierte Dünnschichtsensoren bieten eine kostengünstige Möglichkeit, „online“-Messungen bzw. Vor-Ort-Messungen zeitnah durchzuführen. In dieser Arbeit wird ein potentiometrisches Sensorarray auf der Basis von Chalkogenidgläsern zur Detektion von Schwermetallen in wässrigen Medien vorgestellt.
Y1  - 2012
SN  - 0016-3538
VL  - 56
IS  - 4
SP  - 285
EP  - 287
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Spelthahn, Heiko
A1  - Schaffrath, Sophie
A1  - Coppe, Thomas
A1  - Rufi, Frederic
A1  - Schöning, Michael Josef
T1  - Development of an electrolyte-insulator-semiconductor (EIS) based capacitive heavy metal sensor for the detection of Pb2+ und Cd2+ ions
JF  - Physica status solidi (a) : applications and material science. 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 930
EP  - 934
ER  - 
TY  - JOUR
A1  - Spelthahn, Heiko
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Self-aligned nanogaps and nanochannels via conventional photolithography and pattern-size reduction technique
JF  - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI
Y1  - 2009
SN  - 0013-4686
SP  - 6010
EP  - 6014
ER  - 
TY  - JOUR
A1  - Spelthahn, Heiko
A1  - Kirsanov, Dmitry
A1  - Legin, Andrey
A1  - Osterrath, Thomas
A1  - Schubert, Jürgen
A1  - Zander, Willi
A1  - Schöning, Michael Josef
T1  - Development of a thin-film sensor array for analytical monitoring of heavy metals in aqueous solutions
JF  - Physica Status Solidi (a)
N2  - In industrial processes there is a variety of heavy metals (e.g., copper, zinc, cadmium, and lead) in use for wires, coatings, paints, alloys, batteries, etc. Since the application of these transition metals for industry is inevitable, it is a vital task to develop proper analytical techniques for their monitoring at low activity levels, especially because most of these elements are acutely toxic for biological organisms. The determination of ions in solution by means of a simple and inexpensive sensor array is, therefore, a promising task. In this work, a sensor array with heavy metal-sensitive chalcogenide glass membranes for the simultaneous detection of the four ions Ag⁺, Cu2⁺, Cd2⁺, and Pb2⁺ in solution is realized. The results of the physical characterization by means of microscopy, profilometry, Rutherford backscattering spectroscopy (RBS), and scanning electron microscopy (SEM) as well as the electrochemical characterization by means of potentiometric measurements are presented. Additionally, the possibility to expand the sensor array by polymeric sensor membranes is discussed.
Y1  - 2012
SN  - 1862-6319
U6  - http://dx.doi.org/10.1002/pssa.201100733
VL  - 209
IS  - 5
SP  - 885
EP  - 891
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Sousa, Marcos A. M.
A1  - Siqueira, Jose R. Jr.
A1  - Vercik, Andres
A1  - Schöning, Michael Josef
A1  - Oliveira, Osvaldo N. Jr.
T1  - Determining the optimized layer-by-layer film architecture with dendrimer/carbon nanotubes for field-effect sensors
JF  - IEEE Sensors Journal
N2  - The capacitive electrolyte–insulator–semiconductor (EIS) structure is a typical device based on a field-effect sensor platform. With a simple silicon-based structure, EIS have been useful for several sensing applications, especially with incorporation of nanostructured films to modulate the ionic transport and the flat-band potential. In this paper, we report on ion transport and changes in flat-band potential in EIS sensors made with layer-by-layer films containing poly(amidoamine) (PAMAM) dendrimer and single-walled carbon nanotubes (SWNTs) adsorbed on p-Si/SiO 2 /Ta 2 O 5 chips with an Al ohmic contact. The impedance spectra were fitted using an equivalent circuit model, from which we could determine parameters such as the double-layer capacitance. This capacitance decreased with the number of bilayers owing to space charge accumulated at the electrolyte–insulator interface, up to three PAMAM/SWNTs bilayers, after which it stabilized. The charge-transfer resistance was also minimum for three bilayers, thus indicating that this is the ideal architecture for an optimized EIS performance. The understanding of the influence of nanostructures and the fine control of operation parameters pave the way for optimizing the design and performance of new EIS sensors.
Y1  - 2017
U6  - http://dx.doi.org/10.1109/JSEN.2017.2653238
SN  - 1558-1748
VL  - 17
IS  - 6
SP  - 1735
EP  - 1740
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Slabu, Ioana
A1  - Roeth, Anjali A.
A1  - Engelmann, Ulrich M.
A1  - Wiekhorst, Frank
A1  - Buhl, Eva M.
A1  - Neumann, Ulf P.
A1  - Schmitz-Rode, Thomas
T1  - Modeling of magnetoliposome uptake in human pancreatic tumor cells in vitro
JF  - Nanotechnology
Y1  - 2019
U6  - http://dx.doi.org/10.1088/1361-6528/ab033e
SN  - 1361-6528
VL  - 30
IS  - 18
SP  - 184004
ER  - 
TY  - JOUR
A1  - Siqueira, José R. Jr.
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Zucolotto, Valtencir
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices
JF  - Physica status solidi (a). 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 781
EP  - 786
ER  - 
TY  - JOUR
A1  - Siqueira, José R. Jr.
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Zucolotto, Valtencir
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Penicillin biosensor based on a capacitive field-effect structure functionalized with a dendrimer/carbon nanotube multilayer
JF  - Biosensors and Bioelectronics. 25 (2009), H. 2
Y1  - 2009
SN  - 0956-5663
SP  - 497
EP  - 501
ER  - 
TY  - JOUR
A1  - Siqueira, José R. Jr.
A1  - Abouzar, Maryam H.
A1  - Bäcker, Matthias
A1  - Zucolotto, Valtencir
A1  - Poghossian, Arshak
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Carbon nanotubes in nanostructured films: Potential application as amperometric and potentiometric field-effect (bio-)chemical sensors
JF  - physica status solidi (a) . 206 (2009), H. 3
Y1  - 2009
SN  - 1862-6319
N1  - Special Issue: Engineering of Functional Interfaces (EnFI 08)
SP  - 462
EP  - 467
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Siqueira, Jose R.
A1  - Werner, Frederik
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Zucolotto, Valtencir
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Layer-by-Layer Assembly of Carbon Nanotubes Incorporated in Light-Addressable Potentiometric Sensors
JF  - Journal of Physical Chemistry C. 113 (2009), H. 33
Y1  - 2009
SN  - 1932-7455
SP  - 14765
EP  - 14770
PB  - American Chemical Society
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Siqueira, Jose R.
A1  - Molinnus, Denise
A1  - Beging, Stefan
A1  - Schöning, Michael Josef
T1  - Incorporating a hybrid urease-carbon nanotubes sensitive nanofilm on capacitive field-effect sensors for urea detection
JF  - Analytical chemistry
N2  - The ideal combination among biomolecules and nanomaterials is the key for reaching biosensing units with high sensitivity. The challenge, however, is to find out a stable and sensitive film architecture that can be incorporated on the sensor’s surface. In this paper, we report on the benefits of incorporating a layer-by-layer (LbL) nanofilm of polyamidoamine (PAMAM) dendrimer and carbon nanotubes (CNTs) on capacitive electrolyte-insulator-semiconductor (EIS) field-effect sensors for detecting urea. Three sensor arrangements were studied in order to investigate the adequate film architecture, involving the LbL film with the enzyme urease: (i) urease immobilized directly onto a bare EIS [EIS-urease] sensor; (ii) urease atop the LbL film over the EIS [EIS-(PAMAM/CNT)-urease] sensor; and (iii) urease sandwiched between the LbL film and another CNT layer [EIS-(PAMAM/CNT)-urease-CNT]. The surface morphology of all three urea-based EIS biosensors was investigated by atomic force microscopy (AFM), while the biosensing abilities were studied by means of capacitance–voltage (C/V) and dynamic constant-capacitance (ConCap) measureaments at urea concentrations ranging from 0.1 mM to 100 mM. The EIS-urease and EIS-(PAMAM/CNT)-urease sensors showed similar sensitivity (∼18 mV/decade) and a nonregular signal behavior as the urea concentration increased. On the other hand, the EIS-(PAMAM/CNT)-urease-CNT sensor exhibited a superior output signal performance and higher sensitivity of about 33 mV/decade. The presence of the additional CNT layer was decisive to achieve a urea based EIS sensor with enhanced properties. Such sensitive architecture demonstrates that the incorporation of an adequate hybrid enzyme-nanofilm as sensing unit opens new prospects for biosensing applications using the field-effect sensor platform.
Y1  - 2014
U6  - http://dx.doi.org/10.1021/ac500458s
SN  - 1520-6882 (E-Journal); 0003-2700 (Print); 0096-4484 (Print)
VL  - 86
IS  - 11
SP  - 5370
EP  - 5375
PB  - ACS Publications
CY  - Columbus
ER  - 
TY  - JOUR
A1  - Siqueira, Jose R.
A1  - Maki, Rafael M.
A1  - Paulovich, Fernando V.
A1  - Werner, Frederik
A1  - Poghossian, Arshak
A1  - Oliveira, Maria C. F. de
A1  - Zucolotto, Valtencir
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Use of Information Visualization Methods Eliminating Cross Talk in Multiple Sensing Units Investigated for a Light-Addressable Potentiometric Sensor
JF  - Analytical Chemistry  (2010)
Y1  - 2010
SN  - 0003-2700
SP  - 61
EP  - 65
ER  - 
TY  - CHAP
A1  - Simsek, Beril
A1  - Krause, Hans-Joachim
A1  - Engelmann, Ulrich M.
ED  - Digel, Ilya
ED  - Staat, Manfred
ED  - Trzewik, Jürgen
ED  - Sielemann, Stefanie
ED  - Erni, Daniel
ED  - Zylka, Waldemar
T1  - Magnetic biosensing with magnetic nanoparticles: Simulative approach to predict signal intensity in frequency mixing magnetic detection
T2  - 4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen
N2  - Magnetic nanoparticles (MNP) are investigated with great interest for biomedical applications in diagnostics (e.g. imaging: magnetic particle imaging (MPI)), therapeutics (e.g. hyperthermia: magnetic fluid hyperthermia (MFH)) and multi-purpose biosensing (e.g. magnetic immunoassays (MIA)). What all of these applications have in common is that they are based on the unique magnetic relaxation mechanisms of MNP in an alternating magnetic field (AMF). While MFH and MPI are currently the most prominent examples of biomedical applications, here we present results on the relatively new biosensing application of frequency mixing magnetic detection (FMMD) from a simulation perspective. In general, we ask how the key parameters of MNP (core size and magnetic anisotropy) affect the FMMD signal: by varying the core size, we investigate the effect of the magnetic volume per MNP; and by changing the effective magnetic anisotropy, we study the MNPs’ flexibility to leave its preferred magnetization direction. From this, we predict the most effective combination of MNP core size and magnetic anisotropy for maximum signal generation.
Y1  - 2024
SN  - 978-3-940402-65-3
U6  - http://dx.doi.org/10.17185/duepublico/81475
SP  - 27
EP  - 28
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Ruge, C.
A1  - Müller-Veggian, Mattea
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - A long-term stable macroporoustype EIS structure for electrochemical sensor applications
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 21
EP  - 25
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - New concepts of miniaturised reference electrodes in silicon technology for potentiometric sensor systems
JF  - Sensors and Actuators B. 103 (2004), H. 1-2
Y1  - 2004
SN  - 0925-4005
SP  - 429
EP  - 435
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - Strategies of miniaturised reference electrodes integrated in a silicon-based „one chip“ pH sensor
JF  - Sensors. 3 (2003), H. 9
Y1  - 2003
SN  - 1424-8220
SP  - 330
EP  - 339
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Krings, T.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - A „hybrid“ thin-film pH sensor with integrated thick-film reference
JF  - Sensors. 1 (2001), H. 6
Y1  - 2001
SN  - 1424-8220
SP  - 183
EP  - 192
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Dawgul, M.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Miniaturised reference electrodes for field-effect sensors compatible to silicon chip technology
JF  - Electrochimica Acta. 51 (2005), H. 5
Y1  - 2005
SN  - 0013-4686
U6  - http://dx.doi.org/10.1016/j.electacta.2005.04.063
SP  - 930
EP  - 937
ER  - 
TY  - CHAP
A1  - Sildatke, Michael
A1  - Karwanni, Hendrik
A1  - Kraft, Bodo
A1  - Schmidts, Oliver
A1  - Zündorf, Albert
T1  - Automated Software Quality Monitoring in Research Collaboration Projects
T2  - ICSEW'20: Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops
Y1  - 2020
U6  - http://dx.doi.org/10.1145/3387940.3391478
SP  - 603
EP  - 610
ER  - 
TY  - CHAP
A1  - Siebigteroth, Ines
A1  - Kraft, Bodo
A1  - Schmidts, Oliver
A1  - Zündorf, Albert
T1  - A Study on Improving Corpus Creation by Pair Annotation
T2  - Proceedings of the Poster Session of the 2nd Conference on Language, Data and Knowledge (LDK-PS 2019)
Y1  - 2019
SN  - 1613-0073
SP  - 40
EP  - 44
ER  - 
TY  - JOUR
A1  - Seynnes, O. R.
A1  - Bojsen-Moller, J.
A1  - Albracht, Kirsten
A1  - Arndt, A.
A1  - Cronin, N. J.
A1  - Finni, T.
A1  - Magnusson, S. P.
T1  - Ultrasound-based testing of tendon mechanical properties: a critical evaluation
JF  - Journal of Applied Physiology
Y1  - 2015
U6  - http://dx.doi.org/10.1152/japplphysiol.00849.2014
SN  - 8750-7587
VL  - 118
IS  - 2
SP  - 133
EP  - 141
ER  - 
TY  - THES
A1  - Seifarth, Volker
T1  - Ureteral tissue engineering : development of a bioreactor system and subsequent characterization of the generated biohybrids
Y1  - 2015
N1  - Duisburg, Essen, Universität Duisburg-Essen, Diss., 2015
PB  - Universitätsbibliothek Duisburg-Essen
CY  - Duisburg ; Essen
ER  - 
TY  - JOUR
A1  - Seidova, Seid-Fatima
A1  - Kotliar, Konstantin
A1  - Foerger, Frauke
A1  - Klopfer, Matthias
A1  - Lanzl, Ines
T1  - Functional retinal changes in Gaucher disease
JF  - Documenta Ophthalmologica
Y1  - 2009
SN  - 1573-2622
VL  - 118
IS  - 2
SP  - 151
EP  - 154
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Weißbecker, G.
A1  - Schroth, P.
A1  - Schöning, Michael Josef
T1  - Linkage of inanimate structures to biological systems – smart materials in biological micro- nanosystems
JF  - Smart materials : proceedings of the 1st Caesarium, Bonn, November 17 - 19, 1999 / Karl-Heinz Hoffmann ed.
Y1  - 2001
SN  - 3-540-67957-X
SP  - 149
EP  - 157
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Weißbecker, B.
A1  - Hummel, Hans E.
A1  - Schöning, Michael Josef
A1  - Riemer, A.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Field effect transistor-insect antenna junction
JF  - Naturwissenschaften
Y1  - 1997
SN  - 1432-1904
VL  - 84
SP  - 86
EP  - 88
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Hummel, Hans E.
T1  - An insectbased BioFET as a bioelectronic nose
JF  - Sensors and Actuators B. 65 (2000), H. 1-3
Y1  - 2000
SN  - 0925-4005
SP  - 291
EP  - 295
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Hummel, Hans E.
T1  - An insectbased BioFET as a bioelectronic nose
JF  - Proceedings of the Seventh International Meeting on Chemical Sensors : 27 - 30 July, 1998, Beijing, P. R. China / ed. Zhi-Gang Zhou
Y1  - 1998
N1  - International Meeting on Chemical Sensors ; (7, 1998, Beijing) ; International Meeting on Chemical Sensors (IMCS) ; (7 : ; 1998.07.27-30 : ; Beijing)
SP  - 314
EP  - 316
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Hummel, Hans E.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Zimmermann, S.
A1  - Schwarz, A.
A1  - Kohl, C.-D.
A1  - Koczan, D.
T1  - Applications and perspectives of biosensors based on insect olfaction
JF  - Sensor 99 : proceedings / 9th International Fair and Conference for Sensors, Transducers & Systems, May 18 - 20, 1999, Exhibition Centre Nürnberg/Germany
Y1  - 1999
N1  - Internationale Messe mit Kongreß für Sensoren, Meßaufnehmer & Systeme ; (9, 1999, Nürnberg)
SP  - 99
EP  - 104
PB  - AMA Service
CY  - Wunstorf
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Czynski, J.
A1  - Hummel, Hans E.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - Insect meets microelectronics: A BioFET as a first step to bioelectronic microsystems
JF  - Transducers '99 : proceedings of the Tenth International Conference on Solid-State Sensors and Actuators ; 7 - 10 June, 1999, Sendai, Japan / ed.: S. Middelhoek
Y1  - 2000
N1  - International Conference on Solid State Sensors and Actuators <10, 1999, Sendai, Miyagi-ken> ; Transducers '99 ; (10 : ; 1999.06.07-10 : ; Sendai)
SP  - 1104
EP  - 1107
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Weidenbrück, B.
A1  - Thust, M.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - A silicon-based sensor array with capacitive EIS structures
JF  - Proceedings of the 11th European Conference on Solid-State Transducers / Eurosensors XI, September 21 - 24, 1997, Warsaw, Poland. [Organised by] Warsaw University of Technology. Vol 2.
Y1  - 1997
SN  - 83-908335-0-6
N1  - Eurosensors ; (11, 1997, Warszawa) ; Eurosensors - European Conference on Solid-State Transducers ; (11 : ; 1997.09.21-24 : ; Warsaw)
SP  - 871
EP  - 874
PB  - Sensor Lab Sp.
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Wang, Josepf
A1  - Krause, Robin
A1  - Block, Kirstin
A1  - Musameh, Mustafa
A1  - Mulchandani, Ashok
A1  - Mulchandani, Priti
A1  - Chen, Wilfred
T1  - Dual amperometric-potentiometric biosensor detection system for monitoring organophosphorus neurotoxins
JF  - Analyica Chimica Acta. 469 (2002), H. 2
Y1  - 2002
SN  - 0378-4304
SP  - 197
EP  - 203
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Wang, J.
A1  - Jacobs, M.
A1  - Knobbe, D.-T.
A1  - Muck, A.
T1  - Amperometric PDMS-glass capillary electrophoresis-based biosensor microchip for catechol and dopamine detection
JF  - Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors
Y1  - 2004
N1  - Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba)
SP  - 566
EP  - 567
PB  - Japan Association of Chemical Sensors
CY  - Fukuoka
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Wagner, Torsten
A1  - Wang, C.
A1  - Otto, R.
A1  - Yoshinobu, T.
T1  - Development of a handheld 16 channel pen-type LAPS for electrochemical sensing
JF  - Sensors and Actuators B. 108 (2005)
Y1  - 2005
SN  - 0925-4005
SP  - 808
EP  - 814
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Wagner, Torsten
A1  - Wang, C.
A1  - Otto, R.
A1  - Yoshinobu, T.
T1  - Development of a handheld 16 channel pen-type LAPS for electrochemical sensing
JF  - Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors
Y1  - 2004
N1  - Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba)
SP  - 136
EP  - 137
PB  - Japan Association of Chemical Sensors
CY  - Fukuoka
ER  -