TY - CHAP A1 - Kapoor, Hrshi A1 - Braun, Carsten A1 - Boller, Christian ED - Casciati, Fabio T1 - Modelling and optimisation of maintenance intervals to realize structural health monitoring applications on aircraft T2 - Structural health monitoring 2010 : proceedings of the Fifth European Workshop on Structural Health Monitoring held at Sorrento, Naples, Italy, June 28 - July 4, 2010 ; [EWSHM] Y1 - 2010 SN - 978-1-60595-024-2 SP - 55 EP - 63 PB - DEStech Publ. CY - Lancaster, Pa. ER - TY - CHAP A1 - Kapoor, Hrshi A1 - Boller, Christian A1 - Giljohann, Sebastian A1 - Braun, Carsten T1 - Strategies for structural health monitoring implementation potential assessment in aircraft operational life extension considerations T2 - 2nd International Symposium on NDT in Aerospace : November 22-24, 2010 Hamburg, Germany Y1 - 2010 SN - 978-3-940283-28-3 PB - Dt. Gesellschaft für Zerstörungsfreie Prüfung CY - Berlin ER - TY - JOUR A1 - Kapelyukh, Yury A1 - Henderson, Colin James A1 - Scheer, Nico A1 - Rode, Anja A1 - Wolf, Charles Roland T1 - Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice JF - Drug Metabolism and Disposition Y1 - 2019 U6 - https://doi.org/10.1124/dmd.119.087718 IS - Early view ER - TY - JOUR A1 - Kaminsky, Randolph A1 - Weber, Hans-Joachim A1 - Simons, Antoine A1 - Kallweit, Stephan A1 - Kramm, K. A1 - Verdonck, Pascale T1 - Comparison of the flow downstream two prototypes of a new monoleaflet artificial aortic heart valve by means of PIV visualization JF - Computer methods in biomechanics and biomedical engineering. 8 (2005), H. 4, Suppl. 1 Y1 - 2005 SN - 1476-8259 SP - 159 EP - 160 ER - TY - JOUR A1 - Kaminsky, Randolph A1 - Simons, Antoine A1 - Gatzweiler, Karl-Heinz A1 - Weber, Hans-Joachim T1 - Flow visualization by means of PIV of an artificial aortic heart valve fixed into a mock aorta JF - Acta Mechanica Slovaka 2-A. 9 (2005) Y1 - 2005 SP - 343 EP - 348 ER - TY - BOOK A1 - Kaminsky, Radoslav A1 - Kallweit, Stephan A1 - Weber, Hans-Joachim A1 - Simons, Antoine A1 - Verdonck, Pascal T1 - Stereo high speed PIV measurements behind two different artificial heart valves Y1 - 2006 N1 - International Symposium on Applications of Laser Techniques to Fluid Mechanics <13, 2006, Lisboa> ER - TY - JOUR A1 - Kaminsky, Radoslav A1 - Kallweit, Stephan A1 - Weber, Hans-Joachim A1 - Simons, Antoine A1 - Kramm, K. A1 - Jazwik, K. A1 - Moll, J. A1 - Verdonck, P. T1 - 3D high speed piv assessment of a new aortic heart valve prototype JF - Journal of biomechanics. 39 (2006), H. Supplement 1 Y1 - 2006 SN - 0021-9290 N1 - World Congress of Biomechanics <5, 2006, München>: Abstracts of the 5th World Congress of Biomechanics SP - S304 EP - S305 PB - - ER - TY - JOUR A1 - Kaminsky, Radoslav A1 - Kallweit, Stephan A1 - Weber, Hans-Joachim A1 - Claessens, Tom A1 - Jozwik, Krzystof A1 - Verdonck, Pascal T1 - Flow visualization through two types of aortic prosthetic heart valves using stereoscopic high-speed particle image velocimetry JF - Artificial organs. 31 (2007), H. 12 Y1 - 2007 SN - 1525-1594 SP - 869 EP - 879 ER - TY - JOUR A1 - Kaminsky, Radoslav A1 - Dumont, K. A1 - Weber, Hans-Joachim A1 - Schroll, M. A1 - Verdonck, P. T1 - PIV validation of blood-heart valve leaflet interaction modelling JF - The International journal of artificial organs. 30 (2007), H. 7 Y1 - 2007 SP - 640 EP - 648 PB - - ER - TY - JOUR A1 - Kallweit, Stephan A1 - Willert, Chris A1 - Dues, Michael A1 - Müller, Ulrich T1 - PIV for Volume Flow Metering / Kallweit, Stephan ; Willert, Chris ; Dues, Michael ; Müller, Ulrich ; Lederer, Thomas Y1 - 2008 N1 - 14th International Symposium on Applications of Laser Techniques to Fluid Mechanics, 2008-07-07 - 2008-07-10, Lisbon (Portugal) SP - 6 S. ER - TY - JOUR A1 - Kallweit, Stephan A1 - Vanlanduit, S. A1 - Vanherzeele, J. A1 - Brouns, M. T1 - Time resolved PIV reconstruction of periodic flows / Vanlanduit, S. ; Vanherzeele, J. ; Kallweit, S. ; Brouns, M. ; Guillaume, P. JF - PIV'07, 7th International Symposium on Particle Image Velocimetry, Roma, IT, Sep 11-14, 2007 Y1 - 2007 N1 - PIV, Internional Symposium on Particle Image Velocimetry, 7 ; Datei: Vanlanduit.pdf SP - 1 EP - 14 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Uchiyama, R. A1 - Siekmann, H. T1 - Fault Diagnostic Method for Pump Running Conditions Based on Process Modeling and Neural Network / Uchiyama, R. ; Kallweit, S. ; Siekmann, H. JF - International Journal of Rotating Machinery. 4 (1998), H. 1 Y1 - 1998 SN - 1542-3034 SP - 49 EP - 59 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Schimpf, Axel T1 - Photogrammetric Particle Image Velocimetry / Schimpf, Axel ; Kallweit, Stephan JF - Particle image velocimetry : recent improvements; proceedings of the Europiv 2 Workshop held in Zaragoza, Spain, March 31 - April 1, 2003 / edited by M. Stanislas ... Y1 - 2003 SN - 3-540-21423-2 SP - 295 PB - Springer CY - Berlin ER - TY - JOUR A1 - Kallweit, Stephan A1 - Kaminsky, Radoslav A1 - Rossi, Massimiliano A1 - Morbiducci, Umberto T1 - PIV Measurements of Flows in Artificial Heart Valves / Kaminsky, Radoslav ; Kallweit, Stephan ; Rossi, Massimiliano ; Morbiducci, Umberto ; Scalise, Lorenzo JF - Particle Image Velocimetry - New Developments and Recent Applications Y1 - 2008 SN - 978-3-540-73528-1 N1 - Topics in Applied Physics SP - 55 EP - 72 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Kaminsky, R. A1 - Rossi, M. A1 - Scalise, L. T1 - PIV Measurements with high temporal Resolution behind Artificial Heart Valves / Kaminsky, R. ; Rossi, M. ; Scalise, L. ; Kallweit, S. ; Verdonck, P. JF - Proceedings of the 6th International Symposium on Particle Image Velocimetry Y1 - 2005 N1 - link zum abstract PB - Caltech CY - Pasadena, CA ER - TY - JOUR A1 - Kallweit, Stephan A1 - Kaminsky, R. A1 - Rossi, M. A1 - Morbiducci, U. T1 - Time resolved PIV technique for high temporal resolution measurements of prosthetic heart valves fluid dynamics / Kaminsky, R. ; Rossi, M. ; Morbiducci, U. ; Scalise, L. ; Catellini, P. ; Kallweit, S. ; Verdonck, P. ; Grigioni, M. JF - The International Journal of Artificial Organs. 28 (2005), H. 9 Y1 - 2005 SN - 1724-6040 N1 - Abstracts: XXXII Annual ESAO Congress, 5-8 October 2005, Bologna - Italy SP - 946 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Kaminsky, R. A1 - Rossi, M. A1 - Morbiducci, U. T1 - 2D PIV Study of the flow downstream : Two prototypes of a ney monoleaflet artificial aortic heart valve prosthesis / Kaminsky, R. ; Kramm, K. ; Weber, H. J. ; Simons, A. P. ; Kallweit, S. ; Verdonck, P. R. JF - The International Journal of Artificial Organs. 28 (2005), H. 9 Y1 - 2005 SN - 1724-6040 N1 - Abstracts: XXXII Annual ESAO Congress, 5-8 October 2005, Bologna - Italy SP - 921 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Kaminsky, R. A1 - Rossi, M. A1 - Morbiducci, U. T1 - 3D PIV measurements of prosthetic heart valve dynamics / Kaminsky, R. ; Rossi, M. ; Morbiducci, U. ; Scalise, L. ; Castellini, P. ; Kallweit, S. ; Verdonck, P. ; Grigioni, M. JF - The International Journal of Artificial Organs. 28 (2005), H. 9 Y1 - 2005 SN - 1724-6040 N1 - Abstracts: XXXII Annual ESAO Congress, 5-8 October 2005, Bologna - Italy SP - 868 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Helbing, M. A1 - Orglmeister, R. A1 - Siekmann, H. E. T1 - Image Processing Techniques with Neural Networks for Flow Visualization in Rotating Machinery / Helbing, M. ; Orgimeiste, R. [Orglmeister, R.] ; Kallweit, S. ; Siekmann, H. E. ; Dues, M. ; Cronemeyer, J. JF - FLUCOME '94 : the 4th Triennial International Symposium on Fluid Control, Measurement and Visualization; August 29 - September 1, 1994, Toulouse, France, International Congress Centre, DIGORA-Labège / CERT/ONERA. General chairman Patrick Hebrard Y1 - 1994 SP - 87 EP - 94 CY - Toulouse ER - TY - CHAP A1 - Kallweit, Stephan A1 - Gottschalk, Michael A1 - Walenta, Robert T1 - ROS based safety concept for collaborative robots in industrial applications T2 - Advances in robot design and intelligent control : proceedings of the 24th International Conference on Robotics in Alpe-Adria-Danube Region (RAAD). (Advances in intelligent systems and computing ; 371) N2 - The production and assembly of customized products increases the demand for flexible automation systems. One approach is to remove the safety fences that separate human and industrial robot to combine their skills. This collaboration possesses a certain risk for the human co-worker, leading to numerous safety concepts to protect him. The human needs to be monitored and tracked by a safety system using different sensors. The proposed system consists of a RGBD camera for surveillance of the common working area, an array of optical distance sensors to compensate shadowing effects of the RGBD camera and a laser range finder to detect the co-worker when approaching the work cell. The software for collision detection, path planning, robot control and predicting the behaviour of the co-worker is based on the Robot Operating System (ROS). A first prototype of the work cell shows that with advanced algorithms from the field of mobile robotics a very flexible safety concept can be realized: the robot not simply stops its movement when detecting a collision, but plans and executes an alternative path around the obstacle. KW - Collaborative robot KW - Human-Robot interaction KW - Safety concept KW - Workspace monitoring KW - Path planning Y1 - 2016 SN - 978-3-319-21289-0 (Print) ; 978-3-319-21290-6 (E-Book) U6 - https://doi.org/10.1007/978-3-319-21290-6_3 SP - 27 EP - 35 PB - Springer CY - Cham ER - TY - JOUR A1 - Kallweit, Stephan A1 - Dues, M. W. A1 - Siekmann, H. E. T1 - Spectral Analysis of Pressure Fluctuations and Velocity Fields as Investigated on Propeller Pumps / Dues, M. W. ; Kallweit, S. D. ; Siekmann, H. E. JF - Preprints : Fifth International Symposium on Transport Phenomena and Dynamics of Rotating Machinery (ISROMAC-5) : May 8 - 11, 1994, Maui Marriott Hotel, Kaanapali, Maui, Hawaii, U.S.A / sponsored by Pacific Center of Thermal-Fluids Engineering. [W.-J. Yang, chairman] / Vol. B. Y1 - 1994 N1 - International Symposium on Transport Phenomena and Dynamics of Rotating Machinery 5, 1994, Kaanapali, Hawaii SP - 98 EP - 112 ER - TY - JOUR A1 - Kallweit, Stephan A1 - Dues, M. A1 - Siekmann, H. T1 - Particle-Image-Velocimetry (PIV) in rotierenden Maschinen / Dues, M. ; Kallweit, S. ; Siekmann, H. JF - Lasermethoden in der Strömungsmesstechnik, 3. Fachtagung der Deutschen Gesellschaft für Laser-Anemometrie (GALA), Bremen, DE, 5.-7. Sep, 1994 Y1 - 1994 SN - 3-8265-0162-4 N1 - Lasermethoden in der Strömungsmesstechnik, Fachtagung, 3 SP - 19.1 EP - 19-5 PB - Shaker CY - Aachen ER - TY - CHAP A1 - Kalker, Ines A1 - Toll, B. A1 - Holler, Stefan A1 - Butenweg, Christoph A1 - Topping, B. H. V. A1 - Mota Soares, C. A. T1 - Capacity analysis of textile retrofitted unreinforced masonry T2 - Proceedings of the Seventh International Conference on Computational Structures Technology : [Lisbon, Portugal, 7 - 9 September 2004] / ed. by B. H. V. Topping ... Y1 - 2004 SN - 0-948749-95-4 U6 - https://doi.org/10.4203/ccp.79.194 SP - 431 EP - 432 PB - Civil-Comp Press CY - Stirling ER - TY - CHAP A1 - Kalker, Ines A1 - Neumann, M. A1 - Butenweg, Christoph A1 - Holler, Stefan T1 - Modelling of textile strengthened masonry T2 - Proceedings of the Tenth International Conference on Civil, Structural and Environmental Engineering Computing : [Rome, Italy, 30. August - 2. September 2005] / ed. by B. H. V. Topping Y1 - 2005 SN - 1-905088-00-0 U6 - https://doi.org/10.4203/ccp.81.184 SP - 447 EP - 448 PB - Civil-Comp Press CY - Stirling ER - TY - CHAP A1 - Kalbe, Jochen A1 - Kuropka, Rolf A1 - Meyer-Stork, L. Sebastian A1 - Lauter, S. L. A1 - Höcker, Hartwig A1 - Berndt, Heinz ED - Körner, Andrea T1 - Identification of fine animal hair via DNA analysis T2 - Proceedings of the 1st International Symposium on Specialty Animal Fibers : Aachen, October 26 - 27, 1987 ; [scientific, technological and economical aspects] . - (Schriftenreihe des Deutschen Wollforschungsinstitutes an der Technischen Hochschule Aachen e.V. ; 103) Y1 - 1988 SN - 0930-3723 SP - 221 EP - 227 PB - Dt. Wollforschungsinst. CY - Aachen ER - TY - JOUR A1 - Kalbe, Jochen A1 - Kuropka, Rolf A1 - Meyer-Stork, L. Sebastian A1 - Berndt, Heinz A1 - Sauter, Sybille L. A1 - Loss, Peter A1 - Hendo, Karsten A1 - Riesner, Detlev A1 - Höcker, Hartwig T1 - Isolation and characterization of high-molecular mass DNA from hair shafts JF - Biological chemistry Y1 - 1988 SN - 0177-3593 U6 - https://doi.org/10.1515/bchm3.1988.369.1.413 VL - 369 IS - 1 SP - 413 EP - 416 ER - TY - JOUR A1 - Kalbe, Jochen A1 - Höcker, Hartwig A1 - Berndt, Heinz T1 - Design of enzyme reactors as chromatographic columns for racemic resolution of amino acid esters JF - Chromatographia Y1 - 1989 SN - 0009-5893 U6 - https://doi.org/10.1007/BF02319646 VL - 28 IS - 3-4 SP - 193 EP - 196 ER - TY - CHAP A1 - Kahra, Marvin A1 - Breuß, Michael A1 - Kleefeld, Andreas A1 - Welk, Martin ED - Brunetti, Sara ED - Frosini, Andrea ED - Rinaldi, Simone T1 - An Approach to Colour Morphological Supremum Formation Using the LogSumExp Approximation T2 - Discrete Geometry and Mathematical Morphology N2 - Mathematical morphology is a part of image processing that has proven to be fruitful for numerous applications. Two main operations in mathematical morphology are dilation and erosion. These are based on the construction of a supremum or infimum with respect to an order over the tonal range in a certain section of the image. The tonal ordering can easily be realised in grey-scale morphology, and some morphological methods have been proposed for colour morphology. However, all of these have certain limitations. In this paper we present a novel approach to colour morphology extending upon previous work in the field based on the Loewner order. We propose to consider an approximation of the supremum by means of a log-sum exponentiation introduced by Maslov. We apply this to the embedding of an RGB image in a field of symmetric 2x2 matrices. In this way we obtain nearly isotropic matrices representing colours and the structural advantage of transitivity. In numerical experiments we highlight some remarkable properties of the proposed approach. Y1 - 2024 SN - 978-3-031-57793-2 U6 - https://doi.org/10.1007/978-3-031-57793-2_25 N1 - Third International Joint Conference, DGMM 2024, Florence, Italy, April 15–18, 2024 SP - 325 EP - 337 PB - Springer CY - Cham ER - TY - CHAP A1 - Kahmann, Stephanie Lucina A1 - Uschok, Stephan A1 - Wegmann, Kilian A1 - Müller, Lars-P. A1 - Staat, Manfred T1 - Biomechanical multibody model with refined kinematics of the elbow T2 - 6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK N2 - The overall objective of this study is to develop a new external fixator, which closely maps the native kinematics of the elbow to decrease the joint force resulting in reduced rehabilitation time and pain. An experimental setup was designed to determine the native kinematics of the elbow during flexion of cadaveric arms. As a preliminary study, data from literature was used to modify a published biomechanical model for the calculation of the joint and muscle forces. They were compared to the original model and the effect of the kinematic refinement was evaluated. Furthermore, the obtained muscle forces were determined in order to apply them in the experimental setup. The joint forces in the modified model differed slightly from the forces in the original model. The muscle force curves changed particularly for small flexion angles but their magnitude for larger angles was consistent. Y1 - 2018 ER - TY - JOUR A1 - Kahmann, Stephanie L. A1 - Rausch, Valentin A1 - Plümer, Jonathan A1 - Müller, Lars P. A1 - Pieper, Martin A1 - Wegmann, Kilian T1 - The automized fracture edge detection and generation of three-dimensional fracture probability heat maps JF - Medical Engineering & Physics N2 - With proven impact of statistical fracture analysis on fracture classifications, it is desirable to minimize the manual work and to maximize repeatability of this approach. We address this with an algorithm that reduces the manual effort to segmentation, fragment identification and reduction. The fracture edge detection and heat map generation are performed automatically. With the same input, the algorithm always delivers the same output. The tool transforms one intact template consecutively onto each fractured specimen by linear least square optimization, detects the fragment edges in the template and then superimposes them to generate a fracture probability heat map. We hypothesized that the algorithm runs faster than the manual evaluation and with low (< 5 mm) deviation. We tested the hypothesis in 10 fractured proximal humeri and found that it performs with good accuracy (2.5 mm ± 2.4 mm averaged Euclidean distance) and speed (23 times faster). When applied to a distal humerus, a tibia plateau, and a scaphoid fracture, the run times were low (1–2 min), and the detected edges correct by visual judgement. In the geometrically complex acetabulum, at a run time of 78 min some outliers were considered acceptable. An automatically generated fracture probability heat map based on 50 proximal humerus fractures matches the areas of high risk of fracture reported in medical literature. Such automation of the fracture analysis method is advantageous and could be extended to reduce the manual effort even further. KW - Fracture classification KW - Shoulder KW - Probability distribution mapping KW - Morphing KW - Imaging Y1 - 2022 SN - 1350-4533 VL - 2022 IS - 110 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Kahmann, Stephanie A1 - Hackl, Michael A1 - Wegmann, Kilian A1 - Müller, Lars-Peter A1 - Staat, Manfred ED - Erni, Daniel T1 - Impact of a proximal radial shortening osteotomy on the distribution of forces and the stability of the elbow T2 - 1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen N2 - The human arm consists of the humerus (upper arm), the medial ulna and the lateral radius (forearm). The joint between the humerus and the ulna is called humeroulnar joint and the joint between the humerus and the radius is called humeroradial joint. Lateral and medial collateral ligaments stabilize the elbow. Statistically, 2.5 out of 10,000 people suffer from radial head fractures [1]. In these fractures the cartilage is often affected. Caused by the injured cartilage, degenerative diseases like posttraumatic arthrosis may occur. The resulting pain and reduced range of motion have an impact on the patient’s quality of life. Until now, there has not been a treatment which allows typical loads in daily life activities and offers good long-term results. A new surgical approach was developed with the motivation to reduce the progress of the posttraumatic arthrosis. Here, the radius is shortened by 3 mm in the proximal part [2]. By this means, the load of the radius is intended to be reduced due to a load shift to the ulna. Since the radius is the most important stabilizer of the elbow it has to be confirmed that the stability is not affected. In the first test (Fig. 1 left), pressure distributions within the humeroulnar and humeroradial joints a native and a shortened radius were measured using resistive pressure sensors (I5076 and I5027, Tekscan, USA). The humerus was loaded axially in a tension testing machine (Z010, Zwick Roell, Germany) in 50 N steps up to 400 N. From the humerus the load is transmitted through both the radius and the ulna into the hand which is fixed on the ground. In the second test (Fig. 1 right), the joint stability was investigated using a digital image correlation system to measure the displacement of the ulna. Here, the humerus is fixed with a desired flexion angle and the unconstrained forearm lies on the ground. A rope connects the load actuator with a hook fixed in the ulna. A guide roller is used so that the rope pulls the ulna horizontally when a tensile load is applied. This creates a moment about the elbow joint with a maximum value of 7.5 Nm. Measurements were performed with varying flexion angles (0°, 30°, 60°, 90°, 120°). For both tests and each measurement, seven specimens were used. Student ́s t-test was employed to determine whether the mean values of the measurements in native specimen and operated specimens differ significantly. Y1 - 2016 U6 - https://doi.org/10.17185/duepublico/40821 SP - 7 EP - 8 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram T1 - Corrigendum to “Flight style optimization in ski jumping on normal, large, and ski flying hills” [J. Biomech 47 (2014) 716–722] JF - Journals of Biomechanics Y1 - 2018 U6 - https://doi.org/10.1016/j.jbiomech.2018.02.001 SN - 0021-9290 N1 - refers to Journal of Biomechanics Vol 47, Issue 3, Pages 716-722: https://doi.org/10.1016/j.jbiomech.2013.11.021 SP - 313 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram T1 - Flight style optimization in ski jumping on normal, large, and ski flying hills JF - Journal of biomechanics Y1 - 2013 SN - 1873-2380 (E-Journal); 0021-9290 (Print) N1 - Corrigendum to “Flight style optimization in ski jumping on normal, large, and ski flying hills” [J. Biomech 47 (2014) 716-722] Journal of Biomechanics, 2018;71:313. VL - Vol. 47 IS - Iss. 3 SP - 716 EP - 722 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram ED - Onate, E. T1 - Optimization of the flight style in ski jumping T2 - 11th World Congress on Computational Mechanics (WCCM XI) ; 5th European Conference on Computational Mechanics (ECCM V) ; 6th European Conference on Computational Fluid Dynamics (ECFD VI) ; July 20 - 25, 2014, Barcelona Y1 - 2014 N1 - Das Paper wurde nach der Konferenz überarbeitet. SP - 799 EP - 810 ER - TY - CHAP A1 - Jung, Alexander A1 - Staat, Manfred A1 - Müller, Wolfram T1 - Effect of wind on flight style optimisation in ski jumping T2 - 15th International Symposium on Computer Simulation in Biomechanics ; July 9th-11th 2015, Edinburgh, UK Y1 - 2016 SP - 53 EP - 54 PB - The University of Edinburgh ; Loughborough University CY - Edinburgh ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred T1 - Erratum to "Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue" [GAMM-Mitteilungen, (2019), 42, 4, 10.1002/gamm.201900002] JF - GAMM-Mitteilungen Y1 - 2020 U6 - https://doi.org/10.1002/gamm.202000011 SN - 1522-2608 N1 - Refers to: Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue. Alexander Jung, Manfred Staat. Volume 42, Issue 4. GAMM-Mitteilungen, 2019. https://doi.org/10.1002/gamm.201900002 VL - 43 IS - 4 PB - Wiley-VCH GmbH CY - Weinheim ER - TY - CHAP A1 - Jung, Alexander A1 - Staat, Manfred ED - Erni, Daniel T1 - Computing olympic gold: Ski jumping as an example T2 - 1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen Y1 - 2016 SN - 978-3-940402-06-6 U6 - https://doi.org/10.17185/duepublico/40821 SP - 54 EP - 55 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - JOUR A1 - Jung, Alexander A1 - Staat, Manfred T1 - Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue JF - GAMM - Mitteilungen der Gesellschaft für Angewandte Mathematik und Mechanik Y1 - 2019 U6 - https://doi.org/10.1002/gamm.201900002 SN - 1522-2608 VL - 42 IS - 4 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Jung, Alexander A1 - Müller, Wolfram A1 - Staat, Manfred T1 - Wind and fairness in ski jumping: A computer modelling analysis JF - Journal of Biomechanics N2 - Wind is closely associated with the discussion of fairness in ski jumping. To counter-act its influence on the jump length, the International Ski Federation (FIS) has introduced a wind compensation approach. We applied three differently accurate computer models of the flight phase with wind (M1, M2, and M3) to study the jump length effects of various wind scenarios. The previously used model M1 is accurate for wind blowing in direction of the flight path, but inaccuracies are to be expected for wind directions deviating from the tangent to the flight path. M2 considers the change of airflow direction, but it does not consider the associated change in the angle of attack of the skis which additionally modifies drag and lift area time functions. M3 predicts the length effect for all wind directions within the plane of the flight trajectory without any mathematical simplification. Prediction errors of M3 are determined only by the quality of the input data: wind velocity, drag and lift area functions, take-off velocity, and weight. For comparing the three models, drag and lift area functions of an optimized reference jump were used. Results obtained with M2, which is much easier to handle than M3, did not deviate noticeably when compared to predictions of the reference model M3. Therefore, we suggest to use M2 in future applications. A comparison of M2 predictions with the FIS wind compensation system showed substantial discrepancies, for instance: in the first flight phase, tailwind can increase jump length, and headwind can decrease it; this is opposite of what had been anticipated before and is not considered in the current wind compensation system in ski jumping. Y1 - 2018 U6 - https://doi.org/10.1016/j.jbiomech.2018.05.001 SN - 0021-9290 IS - 75 SP - 147 EP - 153 PB - Elsevier CY - Amsterdam ER - TY - GEN A1 - Jung, Alexander A1 - Müller, Wolfram A1 - Staat, Manfred T1 - Corrigendum to “Wind and fairness in ski jumping: A computer modelling analysis” [J. Biomech. 75 (2018) 147–153] T2 - Journal of Biomechanics Y1 - 2021 U6 - https://doi.org/10.1016/j.jbiomech.2021.110690 SN - 0021-9290 N1 - Refers to: Alexander Jung, Wolfram Müller, Manfred Staat: Wind and fairness in ski jumping: A computer modelling analysis. Journal of Biomechanics, Volume 75. 25 June 2018. Pages 147-153. https://doi.org/10.1016/j.jbiomech.2018.05.001 VL - 128 IS - Article number: 110690 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jung, Alexander A1 - Müller, Wolfram A1 - Staat, Manfred T1 - Optimization of the flight technique in ski jumping: the influence of wind Y1 - 2019 U6 - https://doi.org/10.1016/j.jbiomech.2019.03.023 IS - Early view PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Jung, Alexander A1 - Frotscher, Ralf A1 - Staat, Manfred T1 - Electromechanical model of hiPSC-derived ventricular cardiomyocytes cocultured with fibroblasts T2 - 6th European Conference on Computational Mechanics (ECCM 6), 7th European Conference on Computational Fluid Dynamics (ECFD 7), 11-15 June 2018, Glasgow, UK N2 - The CellDrum provides an experimental setup to study the mechanical effects of fibroblasts co-cultured with hiPSC-derived ventricular cardiomyocytes. Multi-scale computational models based on the Finite Element Method are developed. Coupled electrical cardiomyocyte-fibroblast models (cell level) are embedded into reaction-diffusion equations (tissue level) which compute the propagation of the action potential in the cardiac tissue. Electromechanical coupling is realised by an excitation-contraction model (cell level) and the active stress arising during contraction is added to the passive stress in the force balance, which determines the tissue displacement (tissue level). Tissue parameters in the model can be identified experimentally to the specific sample. Y1 - 2018 ER - TY - THES A1 - Jung, Alexander T1 - Electromechanical modelling and simulation of hiPSC-derived cardiac cell cultures Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?https://nbn-resolving.org/urn:nbn:de:hbz:464-20210624-134942-7 SN - 978-3-9821811-1-0 N1 - Dissertation, Universität Duisburg-Essen, 2021 PB - Universität Duisburg-Essen ER - TY - JOUR A1 - Jossek, Ralf A1 - Bongaerts, Johannes A1 - Sprenger, Georg A. T1 - Characterization of a new feedback-resistant 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase AroF of Escherichia coli JF - FEMS microbiology letters Y1 - 2001 SN - 1574-6968 VL - Vol. 202 IS - Iss. 1 SP - 145 EP - 148 ER - TY - JOUR A1 - Jordan, Sabine D. A1 - Krüger, Markus A1 - Willmes, Diana M. A1 - Redemann, Nora A1 - Wunderlich, F. Thomas A1 - Brönneke, Hella S. A1 - Merkwirth, Carsten A1 - Kashkar, Hamid A1 - Olkkonen, Vesa M. A1 - Böttger, Thomas A1 - Braun, Thomas A1 - Seibler, Jost A1 - Brüning, Jens C. T1 - Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism JF - Nature Cell Biology N2 - The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143–145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143–ORP8 pathway as a potential target for the treatment of obesity-associated diabetes. Y1 - 2011 U6 - https://doi.org/10.1038/ncb2211 SN - 1465-7392 VL - 13 IS - 4 SP - 434 EP - 446 PB - Nature CY - New York ER - TY - CHAP A1 - Jockwer, R. A1 - Kleiber, M. A1 - Uibel, Thomas ED - Görlacher, Rainer T1 - Criteria for Evaluating the Simplification of Design Rules for Dowel-type Fasteners T2 - International Network on Timber Engineering Research, INTER : proceedings, meeting 51, 10 - 13 August 2016, Tallinn, Estonia Y1 - 2018 SP - 461 EP - 466 PB - Timber Scientific Publishing, KIT Holzbau und Baukonstruktionen CY - Karlsruhe ER - TY - JOUR A1 - Jochim, Haldor E. T1 - Charging rail operators for delays – how not to do it JF - Networks for mobility : International Symposium, September 18 - 20, 2002, Stuttgart, Germany ; proceedings / University of Stuttgart, Centre of Transporation Research (FOVUS). W. Möhlenbrink ... (eds.) Y1 - 2002 SN - 3893010858 N1 - International Symposium ; (2002.09.18-20 : ; Stuttgart) PB - FOVUS CY - Stuttgart ER - TY - JOUR A1 - Jochim, Haldor E. T1 - A traffic resistance model of long-distance travel JF - Networks for mobility : 2nd international symposium, September 29 - October 1, 2004, Stuttgart, Germany ; proceedings ; abstracts and CD-ROM / [2nd International Symposium on Networks for Mobility]. FOVUS, Centre of Transportation Research, University of Y1 - 2004 SN - 3-89301-180-3 N1 - International Symposium on Networks for Mobility (2, 2004, Stuttgart) PB - FOVUS CY - Stuttgart ER - TY - JOUR A1 - Jiminez German, Salvador A1 - Behbahani, Mehdi A1 - Miettinen, Susanna A1 - Grijpma, Dirk W. A1 - Haimi, Suvi P. T1 - Proliferation and differentiation of adipose stem cells towards smooth muscle cells on poly(trimethylene carbonate) membranes JF - Macromolecular symposia Y1 - 2013 SN - 0258-0322 VL - Vol. 334 IS - Iss. 1 SP - 133 EP - 142 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Wagner, Torsten A1 - Schöning, Michael Josef A1 - Pieper, Martin T1 - Simulating the electromagnetic‐thermal treatment of thin aluminium layers for adhesion improvement JF - Physica status solidi (a) N2 - A composite layer material used in packaging industry is made from joining layers of different materials using an adhesive. An important processing step in the production of aluminium-containing composites is the surface treatment and consequent coating of adhesive material on the aluminium surface. To increase adhesion strength between aluminium layer and the adhesive material, the foil is heat treated. For efficient heating, induction heating was considered as state-of-the-art treatment process. Due to the complexity of the heating process and the unpredictable nature of the heating source, the control of the process is not yet optimised. In this work, a finite element analysis of the process was established and various process parameters were studied. The process was simplified and modelled in 3D. The numerical model contains an air domain, an aluminium layer and a copper coil fitted with a magnetic field concentrating material. The effect of changing the speed of the aluminium foil (or rolling speed) was studied with the change of the coil current. Statistical analysis was used for generating a general control equation of coil current with changing rolling speed. Y1 - 2015 U6 - https://doi.org/10.1002/pssa.201431893 SN - 1862-6319 VL - Vol. 212 IS - 6 SP - 1234 EP - 1241 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Sterilization of Objects, Products, and Packaging Surfaces and Their Characterization in Different Fields of Industry: The Status in 2020 JF - physica status solidi (a) applications and materials science N2 - The treatment method to deactivate viable microorganisms from objects or products is termed sterilization. There are multiple forms of sterilization, each intended to be applied for a specific target, which depends on—but not limited to—the thermal, physical, and chemical stability of that target. Herein, an overview on the currently used sterilization processes in the global market is provided. Different sterilization techniques are grouped under a category that describes the method of treatment: radiation (gamma, electron beam, X-ray, and ultraviolet), thermal (dry and moist heat), and chemical (ethylene oxide, ozone, chlorine dioxide, and hydrogen peroxide). For each sterilization process, the typical process parameters as defined by regulations and the mode of antimicrobial activity are summarized. Finally, the recommended microorganisms that are used as biological indicators to validate sterilization processes in accordance with the rules that are established by various regulatory agencies are summarized. KW - bioburdens KW - sterility tests KW - sterilization efficacy KW - sterilization methods KW - validation methods Y1 - 2021 U6 - https://doi.org/10.1002/pssa.202000732 SN - 1862-6319 N1 - Corresponding author: Michael J. Schöning VL - 218 IS - 13 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Thermocatalytic Behavior of Manganese (IV) Oxide as Nanoporous Material on the Dissociation of a Gas Mixture Containing Hydrogen Peroxide JF - Nanomaterials N2 - In this article, we present an overview on the thermocatalytic reaction of hydrogen peroxide (H₂O₂) gas on a manganese (IV) oxide (MnO₂) catalytic structure. The principle of operation and manufacturing techniques are introduced for a calorimetric H₂O₂ gas sensor based on porous MnO₂. Results from surface analyses by X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) of the catalytic material provide indication of the H₂O₂ dissociation reaction schemes. The correlation between theory and the experiments is documented in numerical models of the catalytic reaction. The aim of the numerical models is to provide further information on the reaction kinetics and performance enhancement of the porous MnO₂ catalyst. Y1 - 2018 U6 - https://doi.org/10.3390/nano8040262 SN - 2079-4991 VL - 8 IS - 4 PB - MDPI CY - Basel ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Oberländer, Jan A1 - Kirchner, Patrick A1 - Keusgen, Michael A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Experimental and Numerical Analyzes of a Sensor Based on Interdigitated Electrodes for Studying Microbiological Alterations JF - physica status solidi (a): applications and materials science N2 - In this work, a cell-based biosensor to evaluate the sterilization efficacy of hydrogen peroxide vapor sterilization processes is characterized. The transducer of the biosensor is based on interdigitated gold electrodes fabricated on an inert glass substrate. Impedance spectroscopy is applied to evaluate the sensor behavior and the alteration of test microorganisms due to the sterilization process. These alterations are related to changes in relative permittivity and electrical conductivity of the bacterial spores. Sensor measurements are conducted with and without bacterial spores (Bacillus atrophaeus), as well as after an industrial sterilization protocol. Equivalent two-dimensional numerical models based on finite element method of the periodic finger structures of the interdigitated gold electrodes are designed and validated using COMSOL® Multiphysics software by the application of known dielectric properties. The validated models are used to compute the electrical properties at different sensor states (blank, loaded with spores, and after sterilization). As a final result, we will derive and tabulate the frequency-dependent electrical parameters of the spore layer using a novel model that combines experimental data with numerical optimization techniques. Y1 - 2018 U6 - https://doi.org/10.1002/pssa.201700920 SN - 1862-6319 VL - 215 IS - 15 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Vahidpour, Farnoosh A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Development of a package-sterilization process for aseptic filling machines: A numerical approach and validation for surface treatment with hydrogen peroxide JF - Sensor and Actuators A: Physical N2 - Within the present work a sterilization process by a heated gas mixture that contains hydrogen peroxide (H₂O₂) is validated by experiments and numerical modeling techniques. The operational parameters that affect the sterilization efficacy are described alongside the two modes of sterilization: gaseous and condensed H₂O₂. Measurements with a previously developed H₂O₂ gas sensor are carried out to validate the applied H₂O₂ gas concentration during sterilization. We performed microbiological tests at different H₂O₂ gas concentrations by applying an end-point method to carrier strips, which contain different inoculation loads of Geobacillus stearothermophilus spores. The analysis of the sterilization process of a pharmaceutical glass vial is performed by numerical modeling. The numerical model combines heat- and advection-diffusion mass transfer with vapor–pressure equations to predict the location of condensate formation and the concentration of H₂O₂ at the packaging surfaces by changing the gas temperature. For a sterilization process of 0.7 s, a H₂O₂ gas concentration above 4% v/v is required to reach a log-count reduction above six. The numerical results showed the location of H₂O₂ condensate formation, which decreases with increasing sterilant-gas temperature. The model can be transferred to different gas nozzle- and packaging geometries to assure the absence of H₂O₂ residues. Y1 - 2020 U6 - https://doi.org/10.1016/j.sna.2019.111691 SN - 0924-4247 VL - 303 IS - 111691 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Kremers, Alexander A1 - Wagner, Torsten A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - FEM-based modeling of a calorimetric gas sensor for hydrogen peroxide monitoring JF - physica status solidi a : applications and materials sciences N2 - A physically coupled finite element method (FEM) model is developed to study the response behavior of a calorimetric gas sensor. The modeled sensor serves as a monitoring device of the concentration of gaseous hydrogen peroxide (H2 O2) in a high temperature mixture stream in aseptic sterilization processes. The principle of operation of a calorimetric H2 O2 sensor is analyzed and the results of the numerical model have been validated by using previously published sensor experiments. The deviation in the results between the FEM model and experimental data are presented and discussed. Y1 - 2017 U6 - https://doi.org/10.1002/pssa.201600912 SN - 1862-6319 IS - Early View PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Kirchner, Patrick A1 - Baltes, Klaus A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - Development of an in-line evaporation unit for the production of gas mixtures containing hydrogen peroxide – numerical modeling and experimental results JF - International Journal of Heat and Mass Transfer N2 - Hydrogen peroxide (H2O2) is a typical surface sterilization agent for packaging materials used in the pharmaceutical, food and beverage industries. We use the finite-elements method to analyze the conceptual design of an in-line thermal evaporation unit to produce a heated gas mixture of air and evaporated H2O2 solution. For the numerical model, the required phase-transition variables of pure H2O2 solution and of the aerosol mixture are acquired from vapor-liquid equilibrium (VLE) diagrams derived from vapor-pressure formulations. This work combines homogeneous single-phase turbulent flow with heat-transfer physics to describe the operation of the evaporation unit. We introduce the apparent heat-capacity concept to approximate the non-isothermal phase-transition process of the H2O2-containing aerosol. Empirical and analytical functions are defined to represent the temperature- and pressure-dependent material properties of the aqueous H2O2 solution, the aerosol and the gas mixture. To validate the numerical model, the simulation results are compared to experimental data on the heating power required to produce the gas mixture. This shows good agreement with the deviations below 10%. Experimental observations on the formation of deposits due to the evaporation of stabilized H2O2 solution fits the prediction made from simulation results. Y1 - 2019 U6 - https://doi.org/10.1016/j.ijheatmasstransfer.2019.118519 SN - 0017-9310 VL - 143 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Zoor, Annegreth T1 - A new irreversible enzyme-aided esterification method in organic solvents JF - Biotechnology letters. 30 (2008), H. 5 Y1 - 2008 SN - 1573-6776 SP - 925 EP - 928 ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Welsch, Volker T1 - Diketene a New Esterification Reagent in the Enzyme-Aided Synthesis of Chiral Alcohols and Chiral Acetoacetic Acid Esters JF - Tetrahedron Letters . 36 (1995), H. 37 Y1 - 1995 SN - 0040-4039 N1 - ISSN der E-Ausg.: 1359-8562 SP - 6663 EP - 6664 ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Scheidt, Annette T1 - Aliphatic optically active alcohols by enzyme-aided synthesis JF - Tetrahedron Letters . 32 (1991), H. 48 Y1 - 1991 SN - 0040-4039 N1 - ISSN der E-Ausg.: 1359-8562 SP - 7021 EP - 7024 ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Albertz, Michael T1 - Optically active α-acetoxycarboxylic acids and α-hydroxycarboxylic acids by enzyme-aided syntheses JF - Journal für Praktische Chemie / Chemiker-Zeitung. 334 (1992), H. 6 Y1 - 1992 SN - 1436-9966 N1 - ISSN der E-Ausg.: 1521-3897 ; In der Bibliothek (Jülich) vorhanden unter 63 ZS 024-1992 SP - 526 EP - 528 ER - TY - JOUR A1 - Jeromin, Günter Erich T1 - Superabsorbed alcohol dehydrogenase—a new catalyst for asymmetric reductions JF - Biotechnology Letters. 31 (2009), H. 11 Y1 - 2009 SN - 0141-5492 SP - 1717 EP - 1721 ER - TY - JOUR A1 - Jeromin, Günter Erich T1 - Tetrabenzo[a,c,h,j]phenoxazine-18-yl a new stable neutral radical JF - Tetrahedron Letters . 42 (2001), H. 10 Y1 - 2001 SN - 0040-4039 N1 - ISSN der E-Ausg.: 1359-8562 SP - 1863 EP - 1865 ER - TY - JOUR A1 - Jens, Otto A1 - Kaldenhoff, E. A1 - Kirschner-Hermanns, R. A1 - Mühl, Thomas A1 - Klinge, Uwe T1 - Elongation of textile pelvic floor implants under load is related to complete loss of effective porosity, thereby favoring incorporation in scar plates JF - Journal of biomedical materials research. Part A N2 - Use of textile structures for reinforcement of pelvic floor structures has to consider mechanical forces to the implant, which are quite different to the tension free conditions of the abdominal wall. Thus, biomechanical analysis of textile devices has to include the impact of strain on stretchability and effective porosity. Prolift® and Prolift + M®, developed for tension free conditions, were tested by measuring stretchability and effective porosity applying mechanical strain. For comparison, we used Dynamesh-PR4®, which was designed for pelvic floor repair to withstand mechanical strain. Prolift® at rest showed moderate porosity with little stretchability but complete loss of effective porosity at strain of 4.9 N/cm. Prolift + M® revealed an increased porosity at rest, but at strain showed high stretchability, with subsequent loss of effective porosity at strain of 2.5 N/cm. Dynamesh PR4® preserved its high porosity even under strain, but as consequence of limited stretchability. Though in tension free conditions Prolift® and Prolift + M® can be considered as large pore class I meshes, application of mechanical strain rapidly lead to collapse of pores. The loss of porosity at mechanical stress can be prevented by constructions with high structural stability. Assessment of porosity under strain was found helpful to define requirements for pelvic floor devices. Clinical studies have to prove whether devices with high porosity as well as high structural stability can improve the patients' outcome. Y1 - 2014 U6 - https://doi.org/10.1002/jbm.a.34767 SN - 1552-4965 VL - 102 IS - 4 SP - 1079 EP - 1084 PB - Wiley CY - New York ER - TY - CHAP A1 - Jean-Pierre P., de Vera A1 - Baque, Mickael A1 - Billi, Daniela A1 - Böttger, Ute A1 - Bulat, Sergey A1 - Czupalla, Markus A1 - Dachwald, Bernd A1 - de la Torre, Rosa A1 - Elsaesser, Andreas A1 - Foucher, Frédéric A1 - Korsitzky, Hartmut A1 - Kozyrovska, Natalia A1 - Läufer, Andreas A1 - Moeller, Ralf A1 - Olsson-Francis, Karen A1 - Onofri, Silvano A1 - Sommer, Stefan A1 - Wagner, Dirk A1 - Westall, Frances T1 - The search for life on Mars and in the Solar System - strategies, logistics and infrastructures T2 - 69th International Astronautical Congress (IAC) N2 - The question "Are we alone in the Universe?" is perhaps the most fundamental one that affects mankind. How can we address the search for life in our Solar System? Mars, Enceladus and Europa are the focus of the search for life outside the terrestrial biosphere. While it is more likely to find remnants of life (fossils of extinct life) on Mars because of its past short time window of the surface habitability, it is probably more likely to find traces of extant life on the icy moons and ocean worlds of Jupiter and Saturn. Nevertheless, even on Mars there could still be a chance to find extant life in niches near to the surface or in just discovered subglacial lakes beneath the South Pole ice cap. Here, the different approaches for the detection of traces of life in the form of biosignatures including pre-biotic molecules will be presented. We will outline the required infrastructure for this enterprise and give examples of future mission concepts to investigate the presence of life on other planets and moons. Finally, we will provide suggestions on methods, techniques, operations and strategies for preparation and realization of future life detection missions. KW - life detection KW - Mars KW - icy moons KW - habitability KW - space missions Y1 - 2018 N1 - 69th International Astronautical Congress (IAC), Bremen, Germany, 1-5 October 2018. SP - 1 EP - 8 ER - TY - JOUR A1 - Jayaraman, Chandrasekaran A1 - Mummidisetty, Chaitanya Krishna A1 - Loesch, Alexandra A1 - Kaur, Sandi A1 - Hoppe-Ludwig, Shenan A1 - Staat, Manfred A1 - Jayaraman, Arun T1 - Postural and metabolic benefits of using a forearm support walker in older adults with impairments JF - Archives of Physical Medicine and Rehabilitation Y1 - 2019 U6 - https://doi.org/10.1016/j.apmr.2018.10.001 SN - 0003-9993 VL - Volume 100 IS - Issue 4 SP - 638 EP - 647 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Jarke, Matthias A1 - Gebhardt, Michael A1 - Jacobs, Stephan A1 - Nissen, Hans W. T1 - Conflict analysis across heterogeneous viewpoints: formalization and visualization T2 - Proceedings of the 29th Annual Hawaii International Conference on System Sciences Y1 - 1996 SN - 0-8186-7324-9 U6 - https://doi.org/10.1109/HICSS.1996.493191 SP - 199 EP - 208 ER - TY - BOOK A1 - Janz, Norbert A1 - Peters, Bettina T1 - Innovation and Innovation Success in the German Manufacturing Sector. Econometric Evidence at Firm Level / Janz, N. and Peters, B. Y1 - 2002 ER - TY - JOUR A1 - Janz, Norbert A1 - Lööf, Hans A1 - Peters, Bettina T1 - Firm Level Innovation and Productivity, Is there a Common Story Across Countries? JF - Problems and Perspectives in Management (2004) Y1 - 2004 SN - ISSN 1727-7051 N1 - online download: http://businessperspectives.org/files/ppm/PPM_EN_2004_02_Janz.pdf SP - 184 EP - 204 ER - TY - BOOK A1 - Janz, Norbert A1 - Lööf, Hans A1 - Peters, Bettina T1 - Firm Level Innovation and Productivity, Is there a Common Story Across Countries? Y1 - 2003 SN - ISSN 1727-7051 N1 - ZEW Diskussion Paper. No 03-26 Online : ftp://ftp.zew.de/pub/zew-docs/dp/dp0326.pdf PB - Zentrum für Europäische Wirtschaftsforschung ZEW CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Licht, Georg A1 - Ebling, Günther A1 - Niggemann, Hiltrud T1 - Innovation in the Service Sector. Selected Facts and Some Policy Conclusions / Licht, G., G. Ebling, N. Janz, H. Niggemann Y1 - 1999 PB - European Commission CY - Luxembourg ER - TY - BOOK A1 - Janz, Norbert A1 - Licht, Georg T1 - Innovation Activities and European Patenting of German Firms. A Panel Data Analysis / Janz, N., G. Licht Y1 - 2002 ER - TY - BOOK A1 - Janz, Norbert A1 - Gottschalk, Sandra A1 - Hempell, Thomas A1 - Peters, Bettina T1 - Innovation Activities in the German Economy. Report on Indicators from the Innovation Survey 2000 (English translation) / Janz, N., S. Gottschalk, T. Hempell, B. Peters, G. Ebling und H. Niggemann Y1 - 2002 PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Gottschalk, Sandra T1 - Innovation Dynamics and Endogenours Market Structue. An Econometric Investigation with Aggregated Innovation Survey Data / Gottschalk, S. und N. Janz Y1 - 2001 N1 - ZEW-Discussion Paper 01-39 online unter ftp://ftp.zew.de/pub/zew-docs/dp/dp0139.pdf PB - ZEW Zentrum für Europäische Wirtschaftsförderung CY - Mannheim ER - TY - JOUR A1 - Janz, Norbert A1 - Goedhuys, Micheline A1 - Mohnen, Pierre T1 - What drives productivity in Tanzanian manufacturing firms: technology or business environment? / Goedhuys, Micheline ; Janz, Norbert ; Mohnen, Pierre JF - The European Journal of Development Research. 20 (2008), H. 2 Y1 - 2008 SN - 1743-9728 SP - 199 EP - 218 ER - TY - BOOK A1 - Janz, Norbert A1 - Goedhuys, Micheline A1 - Mohnen, Pierre T1 - Knowledge-based productivity in "low-tech" industries : evidence from firms in developing countries / Goedhuys, Micheline ; Janz, Norbert ; Mohnen, Pierre Y1 - 2008 N1 - Working paper series // United Nations University, UNU-MERIT ; 2008,007 PB - UNU-MERIT CY - Maastricht ER - TY - BOOK A1 - Janz, Norbert A1 - Goedhuys, Micheline A1 - Mohnen, Pierre T1 - What drives productivity in Tanzanian manufacturing firms: technology or institutions? / Goedhuys, Micheline ; Janz, Norbert ; Mohnen, Pierre Y1 - 2006 N1 - Working paper series // United Nations University, UNU-MERIT ; 2006,037 PB - UnU-MERIT CY - Maastricht ER - TY - JOUR A1 - Janz, Norbert A1 - Goedhuys, Micheline A1 - Mairesse, Jacques A1 - Mohnen, Pierre T1 - Micro-evidence on innovation and development (MEIDE): an introduction / Goedhuys, Micheline ; Janz, Norbert ; Mairesse, Jacques ; Mohnen, Pierre JF - The European Journal of Development Research. 20 (2008), H. 2 Y1 - 2008 SN - 1743-9728 SP - 167 EP - 171 ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Niggemann, Hiltrud A1 - Stahl, Harald T1 - 2nd Community Innovation Survey. 1st Interim Report. Report prepared for Eurostat / Ebling, G., N. Janz, H. Niggemann und H. Stahl Y1 - 1998 PB - ZEW Zentrum für Europäische Wirtschaftsförderung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Göggerle, J. A1 - Licht, Georg T1 - The Longitudinal Aspect of Innovation Surveys / G. Ebling, J. Göggerle, N. Janz, G. Licht und H. Stahl Y1 - 1998 PB - ZEW Zentrum für Europäische Wirtschaftsförderung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Gottschalk, Sandra A1 - Peters, Bettina T1 - Innovation Activities in the German Economy: Report on indicators from the Innovation Survey 2001 (english translation) / Janz, N., G. Ebling, S. Gottschalk, B. Peters und T. Schmidt Y1 - 2002 PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - JOUR A1 - Janz, Norbert A1 - Ebling, Günther A1 - Gottschalk, Sandra A1 - Niggemann, Hiltrud T1 - The Mannheim Innovation Panels (MIP and MIP-S) of the Centre for European Economic Research (ZEW) / Janz, N., G. Ebling, S. Gottschalk und H. Niggemann JF - Schmollers Jahrbuch : Zeitschrift für Wirtschafts- und Sozialwissenschaften ; journal of applied social science studies. 121 (2001) Y1 - 2001 SN - 0342-1783 SP - 123 EP - 129 ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Gottschalk, Sandra A1 - Niggemann, Hiltrud T1 - Prospects of the German Economy: Innovation Activities in the Manufacturing Sector. Sur­vey 1999 Report to the Federal Ministry of Education and Research (English translation) / Janz, N., G. Ebling, S. Gottschalk und H. Niggemann Y1 - 2000 PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Gottschalk, Sandra A1 - Niggemann, Hiltrud T1 - Services in the Fu­ture: Innovation Activities in the Service Sector. Survey 1999 (English translation) / Janz, N., G. Ebling, S. Gottschalk und H. Niggemann Y1 - 2000 PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Gottschalk, Sandra A1 - Niggemann, Hiltrud T1 - 2nd Community Innovation Survey. Final Report. Report prepared for Eurostat / Ebling, G. , S. Gottschalk, N. Janz und H. Niggemann Y1 - 1999 PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Gottschalk, Sandra A1 - Niggemann, Hiltrud T1 - 2nd Community Innovation Survey. 2nd Interim Report. Report prepared for Eurostat / Ebling, G. , S. Gottschalk, N. Janz und H. Niggemann Y1 - 1999 PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Gottschalk, Sandra A1 - Licht, Georg T1 - Prospects of the German Economy: Innovation Activities in the Manufacturing Sector. Survey 1998 (English translation) / Janz, N., G. Ebling, S. Gottschalk, G. Licht und H. Niggemann Y1 - 1999 PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther A1 - Gottschalk, Sandra A1 - Licht, Georg T1 - Services in the Future. Innovation Activities in the Service Sector. Survey 1998 (English translation) / Janz, N., G. Ebling, S. Gottschalk, G. Licht und H. Niggemann Y1 - 1999 PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - BOOK A1 - Janz, Norbert A1 - Ebling, Günther T1 - Export and Innovation Activities in the German Service Sector. Empirical Evidence at the Firm Level / Ebling, G.. und N. Janz Y1 - 1999 N1 - ZEW-Discussion Paper 99-53 online unter ftp://ftp.zew.de/pub/zew-docs/dp/dp5399.pdf PB - ZEW Zentrum für Europäische Wirtschaftsförderung CY - Mannheim ER - TY - JOUR A1 - Janz, Norbert T1 - Outlier Robust Estimation of an Euler Equation Investment Model with German Firm Level Panel Data JF - Contributions to modern econometrics : from data analysis to economic policy ; [dedicated to Gerd Hansen on the occasion of his 65th Birthday] / ed. by Ingo Klein and Stefan Mittnik Y1 - 2002 SN - 1402073348 N1 - Dynamic modeling in econometrics in economics and finance ; 4 SP - 87 EP - 103 PB - Kluwer Academic Publ. CY - Dordrecht [u.a.] ER - TY - JOUR A1 - Janz, Norbert T1 - Innovative Power of German Manufacturing Industry Slows Down JF - ZEW news. English edition. 4 (2002), H. 2002 Y1 - 2002 SP - 5 EP - 5 ER - TY - JOUR A1 - Janz, Norbert T1 - Innovations in Germany: Market Novelties Gain Greater Importance JF - ZEW news. English edition (2001) Y1 - 2001 SP - 3 EP - 3 ER - TY - BOOK A1 - Janz, Norbert T1 - Interpreting Estimation Result of Euler Equation Investment Models when Factor Markets are Imperfectly Competitive Y1 - 1997 N1 - ZEW-Discussion Paper 97-29 online unter ftp://ftp.zew.de/pub/zew-docs/dp/dp2997.pdf PB - ZEW Zentrum für Europäische Wirtschaftsforschung CY - Mannheim ER - TY - JOUR A1 - Janus, Kevin Alexander A1 - Achtsnicht, Stefan A1 - Tempel, Laura A1 - Drinic, Aleksaner A1 - Kopp, Alexander A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Influence of fibroin membrane composition and curing parameters on the performance of a biodegradable enzymatic biosensor manufactured from Silicon-Free Carbon JF - Physica status solidi : pss. A, Applications and materials science N2 - Herein, fibroin, polylactide (PLA), and carbon are investigated for their suitability as biocompatible and biodegradable materials for amperometric biosensors. For this purpose, screen-printed carbon electrodes on the biodegradable substrates fibroin and PLA are modified with a glucose oxidase membrane and then encapsulated with the biocompatible material Ecoflex. The influence of different curing parameters of the carbon electrodes on the resulting biosensor characteristics is studied. The morphology of the electrodes is investigated by scanning electron microscopy, and the biosensor performance is examined by amperometric measurements of glucose (0.5–10 mM) in phosphate buffer solution, pH 7.4, at an applied potential of 1.2 V versus a Ag/AgCl reference electrode. Instead of Ecoflex, fibroin, PLA, and wound adhesive are tested as alternative encapsulation compounds: a series of swelling tests with different fibroin compositions, PLA, and Ecoflex has been performed before characterizing the most promising candidates by chronoamperometry. Therefore, the carbon electrodes are completely covered with the particular encapsulation material. Chronoamperometric measurements with H2O2 concentrations between 0.5 and 10 mM enable studying the leakage current behavior. KW - amperometric biosensors KW - biocompatible KW - biodegradabl KW - encapsulation materials KW - fibroin Y1 - 2023 U6 - https://doi.org/10.1002/pssa.202300081 SN - 1862-6300 (Print) SN - 1862-6319 (Online) N1 - Corresponding author: Michael J. Schöning VL - 220 IS - 22 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Janus, Kevin Alexander A1 - Achtsnicht, Stefan A1 - Drinic, Aleksander A1 - Kopp, Alexander A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Transient magnesium-based thin-film temperature sensor on a flexible, bioabsorbable substrate for future medical applications JF - Applied Research N2 - In this work, the bioabsorbable materials, namely fibroin, polylactide acid (PLA), magnesium and magnesium oxide are investigated for their application as transient, resistive temperature detectors (RTD). For this purpose, a thin-film magnesium-based meander-like electrode is deposited onto a flexible, bioabsorbable substrate (fibroin or PLA) and encapsulated (passivated) by additional magnesium oxide layers on top and below the magnesium-based electrode. The morphology of different layered RTDs is analyzed by scanning electron microscopy. The sensor performance and lifetime of the RTD is characterized both under ambient atmospheric conditions between 30°C and 43°C, and wet tissue-like conditions with a constant temperature regime of 37°C. The latter triggers the degradation process of the magnesium-based layers. The 3-layers RTDs on a PLA substrate could achieve a lifetime of 8.5 h. These sensors also show the best sensor performance under ambient atmospheric conditions with a mean sensitivity of 0.48 Ω/°C ± 0.01 Ω/°C. KW - Silk fibroin KW - Polylactide acid KW - Bioabsorbable KW - Resistive temperature detector Y1 - 2023 U6 - https://doi.org/10.1002/appl.202300102 SN - 2702-4288 (Print) N1 - Corresponding author: Michael Josef Schöning IS - Accepted manuscript PB - Wiley-VCH ER - TY - BOOK A1 - Janser, Frank A1 - Havermann, Marc T1 - Inkompressible Strömungen Y1 - 2012 SN - 978-3-86130-446-3 N1 - Strömungslehre und Aerodynamik PB - Mainz CY - Aachen ER - TY - JOUR A1 - Jansen, Sebastian A1 - Behbahani, Mehdi A1 - Laumen, Marco A1 - Kaufmann, Tim A1 - Hormes, Marcus A1 - Schmitz-Rode, Thomas A1 - Behr, Marek A1 - Steinseifer, Ulrich T1 - 3D Stereo-PIV Validation for CFD-Simulation of Steady Flow through the Human Aorta using Rapid-Prototyping techniques Y1 - 2010 N1 - abstract ; IV International Symposium on Modelling of Physiological Flows, Sardinia, Italy, June 02-05, 2010 ; MPF2010 ER - TY - JOUR A1 - Jansen, S. V. A1 - Behbahani, Mehdi A1 - Laumen, M. A1 - Kaufmann, T. A1 - Hormes, M. A1 - Behr, Marek A1 - Schmitz-Rode, T. A1 - Steinseifer, U. T1 - Investigation of Steady Flow Through a Realistic Model of the Thoracic Human Aorta Using 3D Stereo PIV and CFD-Simulation JF - ASAIO Journal Y1 - 2010 U6 - https://doi.org/10.1097/01.mat.0000369377.65122.a3 N1 - American Society of Artificial Organs (ASAIO), Baltimore, USA, May 27-29, 2010 VL - 56 IS - 2 SP - 98 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - CHAP A1 - Janotte, N. A1 - Feckler, G. A1 - Kötter, Jens A1 - Decker, Stefan A1 - Herrmann, Ulf A1 - Schmitz, Mark A1 - Lüpfert, E. T1 - Dynamic performance evaluation of the HelioTrough® collector demonstration loop : towards a new benchmark in parabolic trough qualification T2 - SolarPACES International Conference 2013, Las Vegas, Nevada, USA, 17 - 20 September 2013 : [proceedings]. - Pt. 1. - (Energy procedia ; 49) Y1 - 2014 SN - 978-1-63266-904-9 U6 - https://doi.org/10.1016/j.egypro.2014.03.012 SN - 1876-6102 N1 - Nebent.: Power and Chemical Energy Systems concentrating solar power SP - 109 EP - 117 PB - Curran CY - Red Hook, NY ER - TY - JOUR A1 - Jakob, Felix A1 - Martinez, Ronny A1 - Mandawe, John A1 - Hellmuth, Hendrik A1 - Siegert, Petra A1 - Maurer, Karl-Heinz A1 - Schwaneberg, Ulrich T1 - Surface charge engineering of a Bacillus gibsonii subtilisin protease JF - Applied microbiology and biotechnology Y1 - 2013 SN - 1432-0614 (E-Journal); 0171-1741 (Print); 0175-7598 (Print); 0340-2118 (Print) VL - Vol. 97 IS - Iss. 15 SP - 6793 EP - 6802 PB - Springer CY - Berlin ER - TY - JOUR A1 - Jahnke, Siegfried A1 - Roussel, Johanna A1 - Hombach, Thomas A1 - Kochs, Johannes A1 - Fischbach, Andreas A1 - Huber, Gregor A1 - Scharr, Hanno T1 - phenoSeeder - A robot system for automated handling and phenotyping of individual seeds JF - Plant physiology N2 - The enormous diversity of seed traits is an intriguing feature and critical for the overwhelming success of higher plants. In particular, seed mass is generally regarded to be key for seedling development but is mostly approximated by using scanning methods delivering only two-dimensional data, often termed seed size. However, three-dimensional traits, such as the volume or mass of single seeds, are very rarely determined in routine measurements. Here, we introduce a device named phenoSeeder, which enables the handling and phenotyping of individual seeds of very different sizes. The system consists of a pick-and-place robot and a modular setup of sensors that can be versatilely extended. Basic biometric traits detected for individual seeds are two-dimensional data from projections, three-dimensional data from volumetric measures, and mass, from which seed density is also calculated. Each seed is tracked by an identifier and, after phenotyping, can be planted, sorted, or individually stored for further evaluation or processing (e.g. in routine seed-to-plant tracking pipelines). By investigating seeds of Arabidopsis (Arabidopsis thaliana), rapeseed (Brassica napus), and barley (Hordeum vulgare), we observed that, even for apparently round-shaped seeds of rapeseed, correlations between the projected area and the mass of seeds were much weaker than between volume and mass. This indicates that simple projections may not deliver good proxies for seed mass. Although throughput is limited, we expect that automated seed phenotyping on a single-seed basis can contribute valuable information for applications in a wide range of wild or crop species, including seed classification, seed sorting, and assessment of seed quality. Y1 - 2016 U6 - https://doi.org/10.1104/pp.16.01122 SN - 0032-0889 VL - 172 IS - 3 SP - 1358 EP - 1370 PB - Oxford University Press CY - Oxford ER -