TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - "High-order” hybrid FET module for (bio)chemical and physical sensing
JF  - Integrated analytical systems / ed. by Salvador Alegret
Y1  - 2003
SN  - 0-444-51037-0
SP  - 587
EP  - 623
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - "Playing around“ with field-effect sensors on the basis of EIS structures, LAPS and ISFETs
JF  - Sensors. 5 (2005), H. 3
Y1  - 2005
SN  - 1424-8220
SP  - 126
EP  - 138
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
T1  - "Voltohmmetry" – a new transducer principle for electrochemical sensors
JF  - Ultrathin electrochemical chemo- and biosensors : technology and performance / Vladimir M. Mirsky
Y1  - 2004
SN  - 3-540-21285-X
SP  - 117
EP  - 140
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Buniatyan, V. V.
A1  - Matirosyan, N. W.
A1  - Abouzar, Maryam H.
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
A1  - Schubert, J.
A1  - Khachatryan, V. R.
A1  - Soukiassyan, G. R.
T1  - (Ba,Sr)TiO3 based electrolyte-insulator-semiconductor pHsensors: comparitive study
JF  - Semiconductor micro- and nanoelectronics : Proceedings of the Seventh International Conference , Tsakhcadzor, Armenia July 3-5 2009
Y1  - 2009
SP  - 71
EP  - 74
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Lüth, H.
A1  - Schultze, J. W.
A1  - Schöning, Michael Josef
T1  - (Bio-)chemical and physical microsensor array using an identical transducer principle
JF  - Scaling down in electrochemistry : electrochemical micro- and nanosystem technology ; proceedings of the 3rd International Symposium on Electrochemical Microsystem Technologies, Garmisch-Patenkirchen, Germany, 11 - 15 September 2000 / ed. by J. W. Schultz
Y1  - 2001
SN  - 0-08-044014-2
SP  - 243
EP  - 249
PB  - Elsevier [u.a.]
CY  - Amsterdam [u.a.]
ER  - 
TY  - CHAP
A1  - Yoshinobu, Tatsuo
A1  - Krause, Steffi
A1  - Miyamoto, Ko-ichiro
A1  - Werner, Frederik
A1  - Poghossian, Arshak
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
T1  - (Bio-)chemical Sensing and Imaging by LAPS and SPIM
T2  - Label-free biosensing: advanced materials, devices and applications
N2  - The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.
KW  - Chemical imaging
KW  - Field-effect device
KW  - Light-addressable potentiometric sensor
KW  - Potentiometry
Y1  - 2018
SN  - 978-3-319-75219-8
SP  - 103
EP  - 132
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Muschallik, Lukas
A1  - Molinnus, Denise
A1  - Bongaerts, Johannes
A1  - Pohl, Martina
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Siegert, Petra
A1  - Selmer, Thorsten
T1  - (R,R)-Butane-2,3-diol Dehydrogenase from Bacillus clausii DSM 8716T: Cloning and Expression of the bdhA-Gene, and Initial Characterization of Enzyme
JF  - Journal of Biotechnology
N2  - The gene encoding a putative (R,R)-butane-2,3-diol dehydrogenase (bdhA) from Bacillus clausii DSM 8716T was isolated, sequenced and expressed in Escherichia coli. The amino acid sequence of the encoded protein is only distantly related to previously studied enzymes (identity 33–43%) and exhibited some uncharted peculiarities. An N-terminally StrepII-tagged enzyme variant was purified and initially characterized. The isolated enzyme catalyzed the (R)-specific oxidation of (R,R)- and meso-butane-2,3-diol to (R)- and (S)-acetoin with specific activities of 12 U/mg and 23 U/mg, respectively. Likewise, racemic acetoin was reduced with a specific activity of up to 115 U/mg yielding a mixture of (R,R)- and meso-butane-2,3-diol, while the enzyme reduced butane-2,3-dione (Vmax 74 U/mg) solely to (R,R)-butane-2,3-diol via (R)-acetoin. For these reactions only activity with the co-substrates NADH/NAD+ was observed. The enzyme accepted a selection of vicinal diketones, α-hydroxy ketones and vicinal diols as alternative substrates. Although the physiological function of the enzyme in B. clausii remains elusive, the data presented herein clearly demonstrates that the encoded enzyme is a genuine (R,R)-butane-2,3-diol dehydrogenase with potential for applications in biocatalysis and sensor development.
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.jbiotec.2017.07.020
SN  - 0168-1656
VL  - 258
SP  - 41
EP  - 50
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Roderburg, Katharina
A1  - Schöning, Michael Josef
T1  - 1. Graduierten-Tagung : 9. September 2008 / [Hrsg.: K. Roderburg ; M. J. Schöning]
T1  - 1st Graduate Symposium
N2  - Tagungsband der Graduiertentagung der FH Aachen, in dem Doktorandinnen und Doktoranden und ihre Forschungsbereiche vorgestellt werden
T3  - Graduiertentagung / FH Aachen - 1 
KW  - Aachen / Fachhochschule Aachen
KW  - Graduierter
KW  - Promotionsstudium
KW  - Graduiertentagung
KW  - Graduate symposium
Y1  - 2008
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-3125
ER  - 
TY  - CHAP
A1  - Schubert, Nicole
A1  - Schöning, Michael Josef
T1  - 3. Graduiertentagung der FH Aachen
T1  - 3rd Graduate Symposium
N2  - Doktoranden der FH Aachen stellen ihre wissenschaftlichen Arbeiten aus verschiedenen Fachdisziplinen vor.
T3  - Graduiertentagung / FH Aachen - 3 
KW  - Graduiertentagung
Y1  - 2010
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-3386
ER  - 
TY  - JOUR
A1  - Achtsnicht, Stefan
A1  - Tödter, Julia
A1  - Niehues, Julia
A1  - Telöken, Matthias
A1  - Offenhäusser, Andreas
A1  - Krause, Hans-Joachim
A1  - Schröper, Florian
T1  - 3D printed modular immunofiltration columns for frequency mixing-based multiplex magnetic immunodetection
JF  - Sensors
N2  - For performing point-of-care molecular diagnostics, magnetic immunoassays constitute a promising alternative to established enzyme-linked immunosorbent assays (ELISA) because they are fast, robust and sensitive. Simultaneous detection of multiple biomolecular targets from one body fluid sample is desired. The aim of this work is to show that multiplex magnetic immunodetection based on magnetic frequency mixing by means of modular immunofiltration columns prepared for different targets is feasible. By calculations of the magnetic response signal, the required spacing between the modules was determined. Immunofiltration columns were manufactured by 3D printing and antibody immobilization was performed in a batch approach. It was shown experimentally that two different target molecules in a sample solution could be individually detected in a single assaying step with magnetic measurements of the corresponding immobilization filters. The arrangement order of the filters and of a negative control did not influence the results. Thus, a simple and reliable approach to multi-target magnetic immunodetection was demonstrated.
Y1  - 2019
U6  - http://dx.doi.org/10.3390/s19010148
SN  - 1424-8220
VL  - 19
IS  - 1
PB  - MDPI
CY  - Basel
ER  - 
TY  - CHAP
A1  - Schusser, Sebastian
A1  - Vaeßen, Christiane
A1  - Schöning, Michael Josef
T1  - 4. Graduiertentagung der FH Aachen 24. November 2011
T1  - 4th Graduate Symposium FH Aachen - University of Applied Sciences  November  24th, 2011
N2  - Tagungsband der 4. Graduiertentagung der FH Aachen am 24. November 2011 Proceedings from the 4th Graduate Symposium, FH Aachen, Germany, November 24th, 2011 Aachen, November 2011. 62 Seiten
N2  - Proceedings from the 4th Graduate Symposium, FH Aachen, Germany, November 24th, 2011
T3  - Graduiertentagung / FH Aachen - 4 
KW  - Graduiertentagung
Y1  - 2011
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-3530
ER  - 
TY  - CHAP
A1  - Schusser, Sebastian
A1  - Vaeßen, Christiane
A1  - Schöning, Michael Josef
T1  - 5. Graduiertentagung der FH Aachen 15. November 2012
T1  - 5th Graduate Symposium FH Aachen - University of Applied Sciences November 15th, 2012
N2  - Tagungsband der 5. Graduiertentagung der FH Aachen am 15. November 2012
N2  - Proceedings from the 5th Graduate Symposium, FH Aachen, Germany, November 15th, 2012
T3  - Graduiertentagung / FH Aachen - 5 
KW  - Graduiertentagung
Y1  - 2012
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-50425
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Arzdorf, M.
A1  - Mulchandani, P.
A1  - Chen, W.
A1  - Mulchandani, A.
T1  - A capacitive field-effect sensor for the direct determination of organophosphorus pesticides
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 92
EP  - 97
ER  - 
TY  - JOUR
A1  - Haeger, Gerrit
A1  - Bongaerts, Johannes
A1  - Siegert, Petra
T1  - A convenient ninhydrin assay in 96-well format for amino acid-releasing enzymes using an air-stable reagent
JF  - Analytical Biochemistry
N2  - An improved and convenient ninhydrin assay for aminoacylase activity measurements was developed using the commercial EZ Nin™ reagent. Alternative reagents from literature were also evaluated and compared. The addition of DMSO to the reagent enhanced the solubility of Ruhemann's purple (RP). Furthermore, we found that the use of a basic, aqueous buffer enhances stability of RP. An acidic protocol for the quantification of lysine was developed by addition of glacial acetic acid. The assay allows for parallel processing in a 96-well format with measurements microtiter plates.
Y1  - 2022
U6  - http://dx.doi.org/10.1016/j.ab.2022.114819
SN  - 1096-0309
IS  - 624
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Bohrn, Ulrich
A1  - Mucha, Andreas
A1  - Werner, Frederik
A1  - Trattner, Barbara
A1  - Bäcker, Matthias
A1  - Krumbe, Christoph
A1  - Schienle, Meinrad
A1  - Stütz, Evamaria
A1  - Schmitt-Landsiedel, Doris
A1  - Fleischer, Maximilian
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - A critical comparison of cell-based sensor systems for the detection of Cr (VI) in aquatic environment
JF  - Sensors and actuators. B: Chemical
Y1  - 2013
SN  - 1873-3077 (E-Journal); 0925-4005 (Print)
VL  - Vol. 182
SP  - 58
EP  - 65
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Krause, R.
A1  - Block, K.
A1  - Musameh, M.
A1  - Mulchandani, A.
A1  - Wang, J.
T1  - A dual amperometric / potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 76
EP  - 79
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Krause, R.
A1  - Block, K.
A1  - Musahmeh, M.
A1  - Mulchandani, A.
A1  - Wang, J.
T1  - A dual amperometric/potentiometric FIA-based biosensor for the distinctive detection of organophosphorus pesticides
JF  - Sensors and Actuators B. 95 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 291
EP  - 296
ER  - 
TY  - JOUR
A1  - Schiffels, Johannes
A1  - Selmer, Thorsten
T1  - A flexible toolbox to study protein-assisted metalloenzyme assembly in vitro
JF  - Biotechnology and Bioengineering
Y1  - 2015
U6  - http://dx.doi.org/10.1002/bit.25658
SN  - 1097-0290
VL  - 112
IS  - 11
SP  - 2360
EP  - 2372
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Otto, R.
A1  - Yoshinobu, T.
T1  - A handheld 16 channel pen-type LAPS as a platform for (bio-)electrochemical sensing
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 996
EP  - 997
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, K.
A1  - Schöning, Michael Josef
A1  - Yoshinobu, T.
T1  - A high-density multi-point LAPS set-up using a VCSEL array and FPGA control
JF  - Procedia Chemistry. 1 (2009), H. 1
Y1  - 2009
SN  - 1876-6196
N1  - Proceedings of the Eurosensors XXIII conference ; Eurosensors 23
SP  - 1483
EP  - 1486
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Werner, Frederik
A1  - Miyamoto, Ko-Ichiro
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - A high-density multi-point LAPS set-up using a VCSEL array and FPGA control
JF  - Sensors and Actuators B: Chemical. 154 (2011), H. 2
Y1  - 2011
SN  - 1873-3077
N1  - EUROSENSORS XXIII
SP  - 124
EP  - 128
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Miyamoto, Ko-ichiro
A1  - Hayashi, Kosuke
A1  - Sakamoto, Azuma
A1  - Werner, Frederik
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - A high-Q resonance-mode measurement of EIS capacitive sensor by elimination of series resistance
JF  - Sensor and Actuators B: Chemical
N2  - An EIS capacitive sensor is a semiconductor-based potentiometric sensor, which is sensitive to the ion concentration or pH value of the solution in contact with the sensing surface. To detect a small change in the ion concentration or pH, a small capacitance change must be detected. Recently, a resonance-mode measurement was proposed, in which an inductor was connected to the EIS capacitive sensor and the resonant frequency was correlated with the pH value. In this study, the Q factor of the resonant circuit was enhanced by canceling the internal resistance of the reference electrode and the internal resistance of the inductor coil with the help of a bypass capacitor and a negative impedance converter, respectively. 1% variation of the signal in the developed system corresponded to a pH change of 3.93 mpH, which was about 1/12 of the conventional method, suggesting a better performance in detection of a small pH change.
KW  - Negative impedance convertor
KW  - Resonance-mode measurement
KW  - Chemical sensor
KW  - EIS capacitive sensor
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.snb.2017.03.002
SN  - 0925-4005
VL  - 248
SP  - 1006
EP  - 1010
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Dantism, Shahriar
A1  - Röhlen, Desiree
A1  - Wagner, Torsten
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - A LAPS-based differential sensor for parallelized metabolism monitoring of various bacteria
JF  - Sensors
N2  - Monitoring the cellular metabolism of bacteria in (bio)fermentation processes is crucial to control and steer them, and to prevent undesired disturbances linked to metabolically inactive microorganisms. In this context, cell-based biosensors can play an important role to improve the quality and increase the yield of such processes. This work describes the simultaneous analysis of the metabolic behavior of three different types of bacteria by means of a differential light-addressable potentiometric sensor (LAPS) set-up. The study includes Lactobacillus brevis, Corynebacterium glutamicum, and Escherichia coli, which are often applied in fermentation processes in bioreactors. Differential measurements were carried out to compensate undesirable influences such as sensor signal drift, and pH value variation during the measurements. Furthermore, calibration curves of the cellular metabolism were established as a function of the glucose concentration or cell number variation with all three model microorganisms. In this context, simultaneous (bio)sensing with the multi-organism LAPS-based set-up can open new possibilities for a cost-effective, rapid detection of the extracellular acidification of bacteria on a single sensor chip. It can be applied to evaluate the metabolic response of bacteria populations in a (bio)fermentation process, for instance, in the biogas fermentation process.
Y1  - 2019
U6  - http://dx.doi.org/10.3390/s19214692
SN  - 1424-8220
VL  - 19
IS  - 21
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Molina, R.
A1  - Biselli, Manfred
A1  - Canzoneri, Michele
A1  - Schnitzler, Thomas
A1  - Yoshinobu, Tatsuo
A1  - Schöning, Michael Josef
T1  - A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells
JF  - Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.)
Y1  - 2007
SN  - 1-4244-0841-5
N1  - Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon
SP  - 1107
EP  - 1110
PB  - IEEE
CY  - Piscataway
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Ruge, C.
A1  - Müller-Veggian, Mattea
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - A long-term stable macroporoustype EIS structure for electrochemical sensor applications
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 21
EP  - 25
ER  - 
TY  - JOUR
A1  - Moreno i Codinachs, L.
A1  - Birkenstock, C.
A1  - Garma, T.
A1  - Zierold, R.
A1  - Bachmann, J.
A1  - Nielsch, K.
A1  - Schöning, Michael Josef
A1  - Fontcuberta i Morral, A.
T1  - A micron-sized nanoporous multifunction sensing device
JF  - physica status solidi (a) . 206 (2009), H. 3
Y1  - 2009
SN  - 1862-6319
N1  - Special Issue: Engineering of Functional Interfaces (EnFI 08)
SP  - 435
EP  - 441
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Näther, Niko
A1  - Auger, V.
A1  - Poghossian, Arshak
A1  - Koudelka-Hep, M.
A1  - Schöning, Michael Josef
T1  - A miniaturized flow-through cell in SU-8 technique for EIS sensors
JF  - Biomedizinische Technik. 49 (2004), H. 2
Y1  - 2004
SN  - 0932-4666
SP  - 994
EP  - 995
ER  - 
TY  - CHAP
A1  - Ermelenko, Y.
A1  - Yoshinobu, T.
A1  - Mourzina, Y.
A1  - Schöning, Michael Josef
A1  - Vlasov, Y.
A1  - Iwasaki, H.
T1  - A multisensor based on laser scanned silicon transducer (LSST): development and properties
T2  - Eurosensors XVII : the 17th European Conference on Solid-State Transducers ; University of Minho, Guimarães, Portugal, September 21 - 24, 2003
Y1  - 2003
SP  - 72
EP  - 73
ER  - 
TY  - CHAP
A1  - Bäcker, Matthias
A1  - Koch, C.
A1  - Geiger, F.
A1  - Eber, F.
A1  - Gliemann, H.
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - A New Class of Biosensors Based on Tobacco Mosaic Virus and Coat Proteins as Enzyme Nanocarrier
T2  - Procedia Engineering
Y1  - 2016
U6  - http://dx.doi.org/10.1016/j.proeng.2016.11.228
SN  - 1877-7058
N1  - Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary
VL  - Vol. 168
SP  - 618
EP  - 621
ER  - 
TY  - JOUR
A1  - Mourzina, Y.G.
A1  - Schöning, Michael Josef
A1  - Schubert, J.
A1  - Zander, W.
A1  - Legin, A. V.
A1  - Vlasov, Y. G.
A1  - Kordos, P.
A1  - Lüth, H.
T1  - A new thin film Pb microsensor based on chalcogenide glasses
JF  - Sensors and Actuators B. 71 (2000), H. 1-2
Y1  - 2000
SN  - 0925-4005
SP  - 13
EP  - 18
ER  - 
TY  - JOUR
A1  - Näther, Niko
A1  - Emmerich, Rüdiger
A1  - Berger, Jörg
A1  - Friedrich, Peter
A1  - Henkel, Hartmut
A1  - Schneider, Andreas
A1  - Schöning, Michael Josef
T1  - A novel gas-phase hydrogen peroxide sensor basing on a combined physical/chemical transduction mechanism
JF  - Nanofunctional materials, nanostructures, and novel devices for biological and chemical detection : November 27 - December 1, 2006, Boston, Massachusetts, USA ; [at the 2006 MRS Fall Meeting].
Y1  - 2006
SN  - 978-1-60423-407-7
N1  - Materials Research Society symposium proceedings ; 951 ; MRS fall meeting ; (2006.11.27-12.01 : ; Boston, Mass.)
SP  - 63
EP  - 68
PB  - Materials Research Soc.
CY  - Warrendale, Pa.
ER  - 
TY  - JOUR
A1  - Hodel, U.
A1  - Orzati, A.
A1  - Marso, M.
A1  - Homann, O.
A1  - Fox, A.
A1  - Hart, A. v. d.
A1  - Förster, Arnold
A1  - Kordos, P.
A1  - Lüth, H.
T1  - A novel InAlAs/InGaAs layer structure for monolithically integrated photoreceiver
JF  - Conference Proceedings: 2000 International Conference on Indium Phosphide and related materials
Y1  - 2000
SN  - 0-7803-6320-5
N1  - International Conference on Indium Phosphide and Related Materials <12, 2000, Williamsburg, Va.>
SP  - 466
EP  - 469
PB  - IEEE Service Center
CY  - Piscataway, NJ
ER  - 
TY  - JOUR
A1  - Arida, Hassan
A1  - Turek, Monika
A1  - Rolka, David
A1  - Schöning, Michael Josef
T1  - A Novel Thin-Film Copper Array Based on an Organic/Inorganic Sensor Hybrid: Microfabrication, Potentiometric Characterization, and Flow-Injection Analysis Application
JF  - Electroanalysis. 21 (2009), H. 10
Y1  - 2009
SN  - 1040-0397
SP  - 1145
EP  - 1151
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Schöning, Michael Josef
A1  - Abouzar, Maryam H.
A1  - Wagner, Torsten
A1  - Näther, Niko
A1  - Rolka, David
A1  - Yoshinobu, Tatsuo
A1  - Kloock, Joachim P.
A1  - Turek, Monika
A1  - Ingebrandt, Sven
A1  - Poghossian, Arshak
T1  - A semiconductor-based field-effect platform for (bio-)chemical and physical sensors: From capacitive EIS sensors and LAPS over ISFETs to nano-scale devices
T2  - MRS Proceedings
Y1  - 2006
U6  - http://dx.doi.org/10.1557/PROC-0952-F08-02
N1  - Vol. 952 - Symposium F - Integrated Nanosensors
SP  - 1
EP  - 9
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Buß, G.
A1  - Faßbender, F.
A1  - Glück, O.
A1  - Schmitt, G.
A1  - Schultze, J. W.
A1  - Lüth, H.
T1  - A silicon-based microelectrode array for chemical analysis
JF  - Sensors and Actuators B. 65 (2000), H. 1-3
Y1  - 2000
SN  - 0925-4005
SP  - 284
EP  - 287
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Pouyeshman, S.
A1  - Schnitzler, Thomas
A1  - Poghossian, Arshak
A1  - Wagner, Patrick
A1  - Biselli, Manfred
A1  - Schöning, Michael Josef
T1  - A silicon-based multi-sensor chip for monitoring of fermentation processes
JF  - Physica status solidi (a) : applications and material science. 208 (2011), H. 6
Y1  - 2011
SN  - 1862-6319
SP  - 1364
EP  - 1369
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Stock, J.
A1  - Malindretos, J.
A1  - Indlekofer, K.M.
A1  - Pöttgens, Michael
A1  - Förster, Arnold
A1  - Lüth, Hans
T1  - A Vertical Resonant Tunneling Transistor for Application in Digital Logic Circuits
JF  - IEEE Transactions on Electron Devices (T-ED). 48 (2001), H. 6
Y1  - 2001
SN  - 0018-9383
SP  - 1028
EP  - 1032
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Krings, T.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - A „hybrid“ thin-film pH sensor with integrated thick-film reference
JF  - Sensors. 1 (2001), H. 6
Y1  - 2001
SN  - 1424-8220
SP  - 183
EP  - 192
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Kloock, Joachim P.
T1  - About 20 years of silicon-based thin-film sensors with chalcogenide glass materials for heavy metal analysis: Technological aspects of fabrication and miniaturization
JF  - Electroanalysis. 19 (2007), H. 19-20
Y1  - 2007
SN  - 1040-0397
SP  - 2029
EP  - 2038
ER  - 
TY  - RPRT
A1  - Haeger, Gerrit
A1  - Bongaerts, Johannes
A1  - Siegert, Petra
T1  - Abschlussbericht Teil II: Eingehende Darstellung Neue biobasierte Lipopeptide aus nachhaltiger Produktion (LipoPep)
Y1  - 2023
N1  - Förderkennzeichen: 13FH256PA6

Titel: FHprofUnt 2016: Neue biobasierte Lipopeptide aus nachhaltiger Produktion

Laufzeit: 01.02.2019 – 31.10.2022
ER  - 
TY  - RPRT
A1  - Siegert, Petra
A1  - Bongaerts, Johannes
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Selmer, Thorsten
T1  - Abschlussbericht zum Projekt zur Überwachung biotechnologischer Prozesse mittels Diacetyl-/Acetoin-Biosensor und Evaluierung von Acetoin-Reduktasen zur Verwendung in Biotransformationen
Y1  - 2022
N1  - Laufzeit: 01.01.2016 – 31.12.2019 (verlängert bis 31.12.2020)

Förderkennzeichen: 322-8.03.04.02-FH-Struktur 2016/02

Gefördert durch: Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Yoshinobu, T.
A1  - Ecken, H.
A1  - Poghossian, Arshak
A1  - Lüth, H.
A1  - Iwasaki, H.
A1  - Schöning, Michael Josef
T1  - Alternative sensor materials for light-addressable potentiometric sensors
JF  - Sensors and Actuators B. 76 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 388
EP  - 392
ER  - 
TY  - CHAP
A1  - Moritz, Werner
A1  - Yoshinobu, Tatsuo
A1  - Finger, Friedhelm
A1  - Krause, Steffi
A1  - Schöning, Michael Josef
T1  - Amorphous silicon as semiconductor material for high resolution LAPS
T2  - Eurosensors XVII : the 17th European Conference on Solid-State Transducers ; University of Minho, Guimarães, Portugal, September 21 - 24, 2003
Y1  - 2003
SP  - 48
EP  - 49
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Wang, J.
A1  - Jacobs, M.
A1  - Knobbe, D.-T.
A1  - Muck, A.
T1  - Amperometric PDMS-glass capillary electrophoresis-based biosensor microchip for catechol and dopamine detection
JF  - Technical digest of the 10th International Meeting on Chemical Sensors, July 11 - 14, 2004, Tsukuba, Japan / Japan Association of Chemical Sensors
Y1  - 2004
N1  - Chemical sensors ; 20.2004 Suppl. B. IMCS ; (10, 2004, Tsukuba) ; International Meeting on Chemical Sensors ; (10 : ; 2004.07.11-14 : ; Tsukuba)
SP  - 566
EP  - 567
PB  - Japan Association of Chemical Sensors
CY  - Fukuoka
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Jacobs, M.
A1  - Muck, A.
A1  - Knobbe, D.-T.
A1  - Wang, J.
A1  - Chatrathi, M.
A1  - Spillmann, S.
T1  - Amperometric PDMS/glass capillary electrophoresis-based biosensor microchip for catechol and dopamin detection
JF  - Sensors and Actuators B. 108 (2005), H. 1-2
Y1  - 2005
SN  - 0925-4005
N1  - Proceedings of the Tenth International Meeting on Chemical Sensors — IMCS - 10 2004
SP  - 688
EP  - 694
ER  - 
TY  - CHAP
A1  - Wu, Chunsheng
A1  - Poghossian, Arshak
A1  - Werner, Frederik
A1  - Bronder, Thomas
A1  - Bäcker, Matthias
A1  - Wang, Ping
A1  - Schöning, Michael Josef
T1  - An application of a scanning light-addressable potentiometric sensor for label-free DNA detection
T2  - 11. Dresdner Sensor-Symposium : 9.-11.12.2013
Y1  - 2013
SN  - 978-3-9813484-5-3
SP  - 164
EP  - 168
ER  - 
TY  - JOUR
A1  - Schusser, Sebastian
A1  - Poghossian, Arshak
A1  - Bäcker, Matthias
A1  - Krischer, M.
A1  - Leinhos, Marcel
A1  - Wagner, P.
A1  - Schöning, Michael Josef
T1  - An application of field-effect sensors for in-situ monitoring of degradation of biopolymers
JF  - Sensors and actuators B: Chemical
N2  - The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al–p-Si–SiO2–Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13).
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.snb.2014.10.058
SN  - 1873-3077 (E-Journal); 0925-4005 (Print)
VL  - 207, Part B
SP  - 954
EP  - 959
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Pedraza, A. M.
A1  - Gandhi, D.
A1  - Ingebrandt, S.
A1  - Moritz, W.
A1  - Schöning, Michael Josef
T1  - An array of field-effect nanoplate SOI capacitors for (bio-)chemical sensing
JF  - Biosensors and Bioelectronics. 26 (2011), H. 6
Y1  - 2011
SN  - 0956-5663
SP  - 3023
EP  - 3028
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Welden, Rene
A1  - Buniatyan, Vahe V.
A1  - Schöning, Michael Josef
T1  - An Array of On-Chip Integrated, Individually Addressable Capacitive Field-Effect Sensors with Control Gate: Design and Modelling
JF  - Sensors
N2  - The on-chip integration of multiple biochemical sensors based on field-effect electrolyte-insulator-semiconductor capacitors (EISCAP) is challenging due to technological difficulties in realization of electrically isolated EISCAPs on the same Si chip. In this work, we present a new simple design for an array of on-chip integrated, individually electrically addressable EISCAPs with an additional control gate (CG-EISCAP). The existence of the CG enables an addressable activation or deactivation of on-chip integrated individual CG-EISCAPs by simple electrical switching the CG of each sensor in various setups, and makes the new design capable for multianalyte detection without cross-talk effects between the sensors in the array. The new designed CG-EISCAP chip was modelled in so-called floating/short-circuited and floating/capacitively-coupled setups, and the corresponding electrical equivalent circuits were developed. In addition, the capacitance-voltage curves of the CG-EISCAP chip in different setups were simulated and compared with that of a single EISCAP sensor. Moreover, the sensitivity of the CG-EISCAP chip to surface potential changes induced by biochemical reactions was simulated and an impact of different parameters, such as gate voltage, insulator thickness and doping concentration in Si, on the sensitivity has been discussed.
KW  - equivalent circuit
KW  - multianalyte detection
KW  - control gate
KW  - on-chip integrated addressable EISCAP sensors
KW  - capacitive field-effect sensor
Y1  - 2021
U6  - http://dx.doi.org/10.3390/s21186161
SN  - 1424-8220
N1  - This article belongs to the Special Issue "Field-Effect Sensors: From pH Sensing to Biosensing"
VL  - 21
IS  - 18
SP  - 17
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Spiess, Elmar
A1  - Wilfried, Reichardt
A1  - Alvarez, Gerardo
A1  - Gottrup, Marcus
A1  - Öhlschläger, Peter
T1  - An Artificial PAP Gene Breaks Self-tolerance and Promotes Tumor Regression in the TRAMP Model for Prostate Carcinoma
JF  - Molecular Therapy
Y1  - 2011
SN  - 1525-0016
VL  - 20
IS  - 3
SP  - 555
EP  - 564
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Vahidpour, Farnoosh
A1  - Alghazali, Yousef
A1  - Akca, Sevilay
A1  - Hommes, Gregor
A1  - Schöning, Michael Josef
T1  - An Enzyme-Based Interdigitated Electrode-Type Biosensor for Detecting Low Concentrations of H₂O₂ Vapor/Aerosol
JF  - Chemosensors
N2  - This work introduces a novel method for the detection of H₂O₂ vapor/aerosol of low concentrations, which is mainly applied in the sterilization of equipment in medical industry. Interdigitated electrode (IDE) structures have been fabricated by means of microfabrication techniques. A differential setup of IDEs was prepared, containing an active sensor element (active IDE) and a passive sensor element (passive IDE), where the former was immobilized with an enzymatic membrane of horseradish peroxidase that is selective towards H₂O₂. Changes in the IDEs’ capacitance values (active sensor element versus passive sensor element) under H₂O₂ vapor/aerosol atmosphere proved the detection in the concentration range up to 630 ppm with a fast response time (<60 s). The influence of relative humidity was also tested with regard to the sensor signal, showing no cross-sensitivity. The repeatability assessment of the IDE biosensors confirmed their stable capacitive signal in eight subsequent cycles of exposure to H₂O₂ vapor/aerosol. Room-temperature detection of H₂O₂ vapor/aerosol with such miniaturized biosensors will allow a future three-dimensional, flexible mapping of aseptic chambers and help to evaluate sterilization assurance in medical industry.
Y1  - 2022
U6  - http://dx.doi.org/10.3390/chemosensors10060202
SN  - 2227-9040
N1  - This article belongs to the Special Issue "Bioinspired Chemical Sensors and Micro-Nano Devices"
VL  - 10
IS  - 6
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Moseley, Fiona
A1  - Halamek, Jan
A1  - Kramer, Friederike
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
T1  - An enzyme-based reversible CNOT logic gate realized in a flow system
JF  - Analyst
N2  - An enzyme system organized in a flow device was used to mimic a reversible Controlled NOT (CNOT) gate with two input and two output signals. Reversible conversion of NAD⁺ and NADH cofactors was used to perform a XOR logic operation, while biocatalytic hydrolysis of p-nitrophenyl phosphate resulted in an Identity operation working in parallel. The first biomolecular realization of a CNOT gate is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.
Y1  - 2014
U6  - http://dx.doi.org/10.1039/C4AN00133H
SN  - 1364-5528 (E-Journal) ; 0003-2654 (Print)
VL  - 139
IS  - 8
SP  - 1839
EP  - 1842
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Honarvarfard, Elham
A1  - Gamella, Maria
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
T1  - An enzyme-based reversible Controlled NOT (CNOT) logic gate operating on a semiconductor transducer
JF  - Applied Materials Today
N2  - An enzyme-based biocatalytic system mimicking operation of a logically reversible Controlled NOT (CNOT) gate has been interfaced with semiconductor electronic transducers. Electrolyte–insulator–semiconductor (EIS) structures have been used to transduce chemical changes produced by the enzyme system to an electronically readable capacitive output signal using field-effect features of the EIS device. Two enzymes, urease and esterase, were immobilized on the insulating interface of EIS structure producing local pH changes performing XOR logic operation controlled by various combinations of the input signals represented by urea and ethyl butyrate. Another EIS transducer was functionalized with esterase only, thus performing Identity (ID) logic operation for the ethyl butyrate input. Both semiconductor devices assembled in parallel operated as a logically reversible CNOT gate. The present system, despite its simplicity, demonstrated for the first time logically reversible function of the enzyme system transduced electronically with the semiconductor devices. The biomolecular realization of a CNOT gate interfaced with semiconductors is promising for integration into complex biomolecular networks and future biosensor/biomedical applications.
KW  - Electrolyte–insulator–semiconductor
KW  - Capacitive field-effect
KW  - CNOT
KW  - XOR
KW  - Enzyme logic gate
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.apmt.2017.08.003
SN  - 2352-9407
VL  - 9
SP  - 266
EP  - 270
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schiffels, Johannes
A1  - Pinkenburg, Olaf
A1  - Schelden, Maximilian
A1  - Aboulnaga, El-Hussiny A. A.
A1  - Baumann, Marcus
A1  - Selmer, Thorsten
T1  - An innovative cloning platform enables large-scale production and maturation of an oxygen-tolerant [NiFe]-hydrogenase from cupriavidus necator in Escherichia coli
JF  - PLOS one. 2013
Y1  - 2013
U6  - http://dx.doi.org/10.1371/journal.pone.0068812
SN  - 1932-6203
PB  - Public Library of Science
CY  - San Francisco, California
ER  - 
TY  - JOUR
A1  - Schütz, S.
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Kordos, P.
A1  - Lüth, H.
A1  - Hummel, Hans E.
T1  - An insectbased BioFET as a bioelectronic nose
JF  - Sensors and Actuators B. 65 (2000), H. 1-3
Y1  - 2000
SN  - 0925-4005
SP  - 291
EP  - 295
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Simonis, A.
A1  - Lüth, H.
T1  - An ISFET-based penicillin sensor with high sensitivity, low detection limit and long lifetime
JF  - Sensors and Actuators B. 76 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 519
EP  - 526
ER  - 
TY  - JOUR
A1  - Brahma, Aischarya
A1  - Musio, Biagia
A1  - Ismayilova, Uliviya
A1  - Nikbin, Nikzad
A1  - Kamptmann, Sonja B.
A1  - Siegert, Petra
A1  - Jeromin, Günter Erich
A1  - Ley, Steven
A1  - Pohl, Martina
T1  - An orthogonal biocatalytic approach for the safe generation and use of HCN in a multi-step continuous preparation of chiral O-acetylcyanohydrins
JF  - Synlett
Y1  - 2015
U6  - http://dx.doi.org/10.1055/s-0035-1560644
SN  - 0936-5214 (Print) ; 1437-2096 (e-Journal)
IS  - Publ. online 29.09.2015
PB  - Thieme
CY  - Stuttgart
ER  - 
TY  - JOUR
A1  - Murib, Mohammed S.
A1  - Tran, Anh Quang
A1  - Ceuninck, Ward de
A1  - Schöning, Michael Josef
A1  - Nesladek, Milos
A1  - Serpengüzel, Ali
A1  - Wagner, Patrick
T1  - Analysis of an optical biosensor based on elastic light scattering from diamond-, glass-, and sapphire microspheres
JF  - Physica Status Solidi A
N2  - Deoxyribonucleic acid (DNA) and protein recognition are now standard tools in biology. In addition, the special optical properties of microsphere resonators expressed by the high quality factor (Q-factor) of whispering gallery modes (WGMs) or morphology dependent resonances (MDRs) have attracted the attention of the biophotonic community. Microsphere-based biosensors are considered as powerful candidates to achieve label-free recognition of single molecules due to the high sensitivity of their WGMs. When the microsphere surface is modified with biomolecules, the effective refractive index and the effective size of the microsphere change resulting in a resonant wavelength shift. The transverse electric (TE) and the transverse magnetic (TM) elastic light scattering intensity of electromagnetic waves at 600 and 1400 nm are numerically calculated for DNA and unspecific binding of proteins to the microsphere surface. The effect of changing the optical properties was studied for diamond (refractive index 2.34), glass (refractive index 1.50), and sapphire (refractive index 1.75) microspheres with a 50 µm radius. The mode spacing, the linewidth of WGMs, and the shift of resonant wavelength due to the change in radius and refractive index, were analyzed by numerical simulations. Preliminary results of unspecific binding of biomolecules are presented. The calculated shift in WGMs can be used for biomolecules detection.
Y1  - 2012
U6  - http://dx.doi.org/10.1002/pssa.201100795
SN  - 1862-6319
N1  - Special Issue: "Fundamentals and Applications of Diamond"
VL  - 209
IS  - 9
SP  - 1804
EP  - 1810
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Heiden, W.
A1  - Turek, M.
A1  - Schöning, Michael Josef
T1  - Analysis of chemical sensor data
JF  - Proceedings of the 4th Russian-German Workshop "Innovation Information Technologies: Theory and practice" : Ufa, Russia, April 8-13, 2011 / eds. Yupsova, Nafisa ...
Y1  - 2011
SN  - 978-5-4221-0159-7
SP  - 76
EP  - 81
PB  - State Aviation Technical Univ.
CY  - Ufa
ER  - 
TY  - JOUR
A1  - Mourzina, Y. G.
A1  - Ermelenko, Y. E.
A1  - Yoshinobu, T.
A1  - Vlasov, Y.
A1  - Iwasaki, H.
A1  - Schöning, Michael Josef
T1  - Anionselective light-addressable potentiometric sensors (LAPS) for the determination of nitrate and suphate ions
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 32
EP  - 38
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schultze, J. W.
A1  - Schöning, Michael Josef
T1  - Application of a (bio-)chemical sensor (ISFET) for the detection of physical parameters in liquids
JF  - Electrochimica Acta. 48 (2003), H. 20-22
Y1  - 2003
SP  - 3289
EP  - 3297
ER  - 
TY  - JOUR
A1  - Pilas, Johanna
A1  - Yazici, Y.
A1  - Selmer, Thorsten
A1  - Keusgen, M.
A1  - Schöning, Michael Josef
T1  - Application of a portable multi-analyte biosensor for organic acid determination in silage
JF  - Sensors
N2  - Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at −21 °C, +4 °C, and room temperature) over a period of 140 days. After repeated and regular application, the individual sensing electrodes exhibited the best stability when stored at −21 °C. Furthermore, measurements in silage samples (maize and sugarcane silage) were conducted with the portable biosensor system. Comparison with a conventional photometric technique demonstrated successful employment for rapid monitoring of complex media.
Y1  - 2018
U6  - http://dx.doi.org/10.3390/s18051470
SN  - 1424-8220
VL  - 18
IS  - 5
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Miyamato, Ko-ichiro
A1  - Sakakita, Sakura
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Application of chemical imaging sensor to in-situ pH imaging in the vicinity of a corroding metal surface
JF  - Electrochimica Acta
N2  - The chemical imaging sensor was applied to in-situ pH imaging of the solution in the vicinity of a corroding surface of stainless steel under potentiostatic polarization. A test piece of polished stainless steel was placed on the sensing surface leaving a narrow gap filled with artificial seawater and the stainless steel was corroded under polarization. The pH images obtained during polarization showed correspondence between the region of lower pH and the site of corrosion. It was also found that the pH value in the gap became as low as 2 by polarization, which triggered corrosion.
Y1  - 2015
U6  - http://dx.doi.org/10.1016/j.electacta.2015.07.184
SN  - 0013-4686
VL  - 183
SP  - 137
EP  - 142
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Baade, A.
A1  - Emons, H.
A1  - Schöning, Michael Josef
T1  - Application of ISFET for pH measurements in rain droplets
JF  - Sensors and Actuators B. 76 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 634
EP  - 638
ER  - 
TY  - JOUR
A1  - Yoshinobu, Tatsuo
A1  - Moritz, Werner
A1  - Finger, Friedhelm
A1  - Schöning, Michael Josef
ED  - Comini, Elisabetta
T1  - Application of thin-film amorphous silicon to chemical imaging
JF  - Nanostructured materials and hybrid composites for gas sensors and biomedical applications : symposium held April 18-20, 2006, San Francisco , California, U.S.A.
Y1  - 2006
SN  - 9781558998711
N1  - Materials Research Society symposia proceedings; v. 915
IS  - Paper 0910-A-20-01
SP  - 1
EP  - 10
ER  - 
TY  - JOUR
A1  - Yoshinobu, T.
A1  - Yasuhito, U.
A1  - Iwasaki, H.
A1  - Näther, Niko
A1  - Schöning, Michael Josef
A1  - Koudelka-Hep, M.
T1  - Applications of the light-addressable potentiometric sensor to microfluidic devices
JF  - Digest of technical papers : September 12 - 15, 2004, Rome, Italy, Pontificia Universitas Sancto Thoma Aquinate in Urbe / [conference chairperson: C. Di Natale].
Y1  - 2004
SN  - 88-7621-282-5
N1  - Eurosensors ; (18, 2004, Roma)
SP  - 434
EP  - 437
CY  - Roma
ER  - 
TY  - JOUR
A1  - Figueroa-Miranda, Gabriela
A1  - Feng, Lingyan
A1  - Shiu, Simon Chi-Chin
A1  - Dirkzwager, Roderick Marshall
A1  - Cheung, Yee-Wai
A1  - Tanner, Julian Alexander
A1  - Schöning, Michael Josef
A1  - Offenhäusser, Andreas
A1  - Mayer, Dirk
T1  - Aptamer-based electrochemical biosensor for highly sensitive and selective malaria detection with adjustable dynamic response range and reusability
JF  - Sensor and Actuators B: Chemical
N2  - Malaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a novel aptamer-based electrochemical biosensor (aptasensor) for malaria detection by impedance spectroscopy, through the specific recognition between a highly discriminatory DNA aptamer and its target Plasmodium falciparum lactate dehydrogenase (PfLDH). Interestingly, due to the isoelectric point (pI) of PfLDH, the aptasensor response showed an adjustable detection range based on the different protein net-charge at variable pH environments. The specific aptamer recognition allows sensitive protein detection with an expanded detection range and a low detection limit, as well as a high specificity for PfLDH compared to analogous proteins. The specific feasibility of the aptasensor is further demonstrated by detection of the target PfLDH in human serum. Furthermore, the aptasensor can be easily regenerated and thus applied for multiple usages. The robustness, sensitivity, and reusability of the presented aptasensor make it a promising candidate for point-of-care diagnostic systems.
Y1  - 2018
U6  - http://dx.doi.org/10.1016/j.snb.2017.07.117
SN  - 0925-4005
VL  - 255
IS  - P1
SP  - 235
EP  - 243
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Turek, M.
A1  - Heiden, W.
A1  - Riesen, A.
A1  - Chhabda, T. A.
A1  - Schubert, J.
A1  - Krüger, P.
A1  - Keusgen, M.
T1  - Artificial intelligence/fuzzy logic method for analysis of combined signals from heavy metal chemical sensors
JF  - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI
Y1  - 2009
SN  - 0013-4686
SP  - 6082
EP  - 6088
PB  - Elsevier
CY  - New York
ER  - 
TY  - JOUR
A1  - Vahidpour, Farnoosh
A1  - Guthman, Eric
A1  - Arreola, Julia
A1  - Alghazali, Yousef H. M.
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
T1  - Assessment of Various Process Parameters for Optimized Sterilization Conditions Using a Multi-Sensing Platform
JF  - Foods
N2  - In this study, an online multi-sensing platform was engineered to simultaneously evaluate various process parameters of food package sterilization using gaseous hydrogen peroxide (H₂O₂). The platform enabled the validation of critical aseptic parameters. In parallel, one series of microbiological count reduction tests was performed using highly resistant spores of B. atrophaeus DSM 675 to act as the reference method for sterility validation. By means of the multi-sensing platform together with microbiological tests, we examined sterilization process parameters to define the most effective conditions with regards to the highest spore kill rate necessary for aseptic packaging. As these parameters are mutually associated, a correlation between different factors was elaborated. The resulting correlation indicated the need for specific conditions regarding the applied H₂O₂ gas temperature, the gas flow and concentration, the relative humidity and the exposure time. Finally, the novel multi-sensing platform together with the mobile electronic readout setup allowed for the online and on-site monitoring of the sterilization process, selecting the best conditions for sterility and, at the same time, reducing the use of the time-consuming and costly microbiological tests that are currently used in the food package industry.
KW  - spore kill rate
KW  - sterility
KW  - aseptic parameters
KW  - multi-sensing platform
KW  - gaseous hydrogen peroxide
Y1  - 2022
U6  - http://dx.doi.org/10.3390/foods11050660
SN  - 2304-8158
N1  - This article belongs to the Special Issue "Sensors and Biosensors Application for Food Industries"
VL  - 11
IS  - 5
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Siqueira, José R. Jr.
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Zucolotto, Valtencir
A1  - Oliveira, Osvaldo N. Jr.
A1  - Schöning, Michael Josef
T1  - Associating biosensing properties with the morphological structure of multilayers containing carbon nanotubes on field-effect devices
JF  - Physica status solidi (a). 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 781
EP  - 786
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Wagner, H.
A1  - Schöning, Michael Josef
T1  - Automatisiertes „wafer level“-Testsystem zur Charakterisierung von siliziumbasierten Chemo- und Biosensoren
JF  - Sensoren und Messsysteme 2010 [Elektronische Ressource] : Vorträge der 15. ITG/GMA-Fachtagung vom 18. bis 19. Mai 2010 in Nürnberg / Informationstechnische Gesellschaft im VDE (ITG); VDI/VDE-Gesellschaft Mess- und Automatisierungstechnik (GMA)
Y1  - 2010
SN  - 978-3-8007-3260-9
N1  - Fachtagung Sensoren und Messsysteme 15, 2010, Nürnberg ; Gesellschaft Mess- und Automatisierungstechnik
SP  - 89
EP  - 92
PB  - VDE Verlag
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Buniatyan, V.
A1  - Huck, Christina
A1  - Poghossian, Arshak
A1  - Aroutiounian, V. M.
A1  - Schöning, Michael Josef
T1  - BaxSr1-x TiO3/pc-Si heterojunction
JF  - Armenian journal of physics
Y1  - 2013
SN  - 1829-1171
VL  - 6
IS  - 4
SP  - 177
EP  - 187
PB  - National Academy of Sciences of Armenia
CY  - Yerevan
ER  - 
TY  - JOUR
A1  - Buniatyan, V.
A1  - Huck, Christina
A1  - Poghossian, Arshak
A1  - Aroutiounian, V. M.
A1  - Schöning, Michael Josef
T1  - BaxSr1-x TiO3/pc-Si heterojunction capacitance
JF  - Armenian journal of physics
Y1  - 2013
SN  - 1829-1171
VL  - 6
IS  - 4
SP  - 188
EP  - 197
PB  - National Academy of Sciences of Armenia
CY  - Yerevan
ER  - 
TY  - JOUR
A1  - Darmo, J.
A1  - Schäffer, F.
A1  - Förster, Arnold
A1  - Kordos, P.
T1  - Beryllium doped low-temperature-grown MBE GaAs: material for photomixing in the THz frequency range
JF  - ASDAM 2000 : conference proceedings / edited by Jozef Osvald ... [et al.]
Y1  - 2000
SN  - 0780359399
N1  - International Conference on Advanced Semiconductor Devices and Microsystems ; (3rd : ; 2000 : ; Smolenice, Slovakia)
SP  - 147
EP  - 150
PB  - IEEE
CY  - Piscataway, NJ
ER  - 
TY  - JOUR
A1  - Werner, Frederik
A1  - Groebel, Simone
A1  - Schuhmacher, K.
A1  - Spelthahn, Heiko
A1  - Wagner, Torsten
A1  - Selmer, Thorsten
A1  - Baumann, Marcus
A1  - Schöning, Michael Josef
T1  - Bestimmung der metabolischen Aktivität von Mikroorganismen während des Biogasbildungsprozesses
JF  - 9. Dresdner Sensor-Symposium : Dresden, 07.-09. Dezember 2009 / Gerlach, Gerald ; Hauptmann, Peter [Hrsg.]
Y1  - 2009
SN  - 978-3-941298-44-6
N1  - Dresdner Sensor-Symposium ; (9, 2009, Dresden)
SP  - 201
EP  - 204
PB  - TUDpress
CY  - Dresden
ER  - 
TY  - JOUR
A1  - Kramer, Friederike
A1  - Halamkova, Lenka
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
A1  - Halamek, Jan
T1  - Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American
JF  - The analyst. August 2013
Y1  - 2013
SN  - 1364-5528 (E-Journal); 0003-2654 (Print)
VL  - Vol. 138
SP  - 6251
EP  - 6257
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Falkenberg, Fabian
A1  - Kohn, Sophie
A1  - Bott, Michael
A1  - Bongaerts, Johannes
A1  - Siegert, Petra
T1  - Biochemical characterisation of a novel broad pH spectrum subtilisin from Fictibacillus arsenicus DSM 15822ᵀ
JF  - FEBS Open Bio
N2  - Subtilisins from microbial sources, especially from the Bacillaceae family, are of particular interest for biotechnological applications and serve the currently growing enzyme market as efficient and novel biocatalysts. Biotechnological applications include use in detergents, cosmetics, leather processing, wastewater treatment and pharmaceuticals. To identify a possible candidate for the enzyme market, here we cloned the gene of the subtilisin SPFA from Fictibacillus arsenicus DSM 15822ᵀ (obtained through a data mining-based search) and expressed it in Bacillus subtilis DB104. After production and purification, the protease showed a molecular mass of 27.57 kDa and a pI of 5.8. SPFA displayed hydrolytic activity at a temperature optimum of 80 °C and a very broad pH optimum between 8.5 and 11.5, with high activity up to pH 12.5. SPFA displayed no NaCl dependence but a high NaCl tolerance, with decreasing activity up to concentrations of 5 m NaCl. The stability enhanced with increasing NaCl concentration. Based on its substrate preference for 10 synthetic peptide 4-nitroanilide substrates with three or four amino acids and its phylogenetic classification, SPFA can be assigned to the subgroup of true subtilisins. Moreover, SPFA exhibited high tolerance to 5% (w/v) SDS and 5% H₂O₂ (v/v). The biochemical properties of SPFA, especially its tolerance of remarkably high pH, SDS and H₂O₂, suggest it has potential for biotechnological applications.
KW  - Bacillaceae
KW  - Biotechnological application
KW  - Broad pH spectrum
KW  - Subtilases
KW  - Subtilisin
Y1  - 2023
U6  - http://dx.doi.org/10.1002/2211-5463.13701
SN  - 2211-5463
N1  - Corresponding author: Petra Siegert
VL  - 13
IS  - 11
SP  - 2035
EP  - 2046
PB  - Wiley
CY  - Hoboken, NJ
ER  - 
TY  - JOUR
A1  - Falkenberg, Fabian
A1  - Rahba, Jade
A1  - Fischer, David
A1  - Bott, Michael
A1  - Bongaerts, Johannes
A1  - Siegert, Petra
T1  - Biochemical characterization of a novel oxidatively stable, halotolerant, and high-alkaline subtilisin from Alkalihalobacillus okhensis Kh10-101T
JF  - FEBS Open Bio
N2  - Halophilic and halotolerant microorganisms represent a promising source of salt-tolerant enzymes suitable for various biotechnological applications where high salt concentrations would otherwise limit enzymatic activity. Considering the current growing enzyme market and the need for more efficient and new biocatalysts, the present study aimed at the characterization of a high-alkaline subtilisin from Alkalihalobacillus okhensis Kh10-101T. The protease gene was cloned and expressed in Bacillus subtilis DB104. The recombinant protease SPAO with 269 amino acids belongs to the subfamily of high-alkaline subtilisins. The biochemical characteristics of purified SPAO were analyzed in comparison with subtilisin Carlsberg, Savinase, and BPN'. SPAO, a monomer with a molecular mass of 27.1 kDa, was active over a wide range of pH 6.0–12.0 and temperature 20–80 °C, optimally at pH 9.0–9.5 and 55 °C. The protease is highly oxidatively stable to hydrogen peroxide and retained 58% of residual activity when incubated at 10 °C with 5% (v/v) H2O2 for 1 h while stimulated at 1% (v/v) H2O2. Furthermore, SPAO was very stable and active at NaCl concentrations up to 5.0 m. This study demonstrates the potential of SPAO for biotechnological applications in the future.
KW  - Alkalihalobacillus okhensis
KW  - detergent protease
KW  - halotolerant protease
KW  - high-alkaline subtilisin
KW  - oxidative stable protease
Y1  - 2022
U6  - http://dx.doi.org/10.1002/2211-5463.13457
SN  - 2211-5463
N1  - Corresponding author: Petra Siegert
VL  - 12
IS  - 10
SP  - 1729
EP  - 1746
PB  - Wiley
CY  - Hoboken, NJ
ER  - 
TY  - JOUR
A1  - Lüth, H.
A1  - Thust, M.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Schöning, Michael Josef
T1  - Biochemical sensors with structured and porous silicon capacitors
JF  - Materials Science and Engineering B. 69-70 (2000)
Y1  - 2000
SN  - 0921-5107
SP  - 104
EP  - 108
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Schütz, S.
A1  - Ecken, H.
A1  - Yoshinobu, T.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices
JF  - Lecture Notes of the ICB Seminars
Y1  - 2002
SP  - 28
EP  - 42
PB  - MCB
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Schroth, P.
A1  - Weißbecker, B.
A1  - Schütz, S.
A1  - Ecken, H.
A1  - Yoshinobu, T.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Bioelectronic signal processing - intact chemoreceptors coupled to field-effect devices
JF  - Biocybernetics and Biomedical Engineering. 21 (2001), H. 3
Y1  - 2001
SN  - 0208-5216
SP  - 27
EP  - 42
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
T1  - BioFEDs (field-effect devices) : State-of-the-art and new directions
JF  - Electroanalysis
Y1  - 2006
U6  - http://dx.doi.org/10.1002/elan.200603609
SN  - 1521-4109
VL  - 18
IS  - 19-20
SP  - 1893
EP  - 1900
ER  - 
TY  - CHAP
A1  - Kasper, Katharina
A1  - Schiffels, Johannes
A1  - Krafft, Simone
A1  - Kuperjans, Isabel
A1  - Elbers, Gereon
A1  - Selmer, Thorsten
T1  - Biogas Production on Demand Regulated by Butyric Acid Addition
T2  - IOP Conference Series: Earth and Environmental Science. Bd. 32
Y1  - 2016
U6  - http://dx.doi.org/10.1088/1755-1315/32/1/012009
SN  - 1755-1315
N1  - ICARET 2016, International Conference on Advances in Renewable Energy and Technologies, Putrajaya, MY, Feb 23-25, 2016
VL  - 32
SP  - 012009/1
EP  - 012009/4
ER  - 
TY  - JOUR
A1  - Oliveira, Danilo A.
A1  - Molinnus, Denise
A1  - Beging, Stefan
A1  - Siqueira Jr, José R.
A1  - Schöning, Michael Josef
T1  - Biosensor Based on Self-Assembled Films of Graphene Oxide and Polyaniline Using a Field-Effect Device Platform
JF  - physica status solidi (a) applications and materials science
N2  - A new functionalization method to modify capacitive electrolyte–insulator–semiconductor (EIS) structures with nanofilms is presented. Layers of polyallylamine hydrochloride (PAH) and graphene oxide (GO) with the compound polyaniline:poly(2-acrylamido-2-methyl-1-propanesulfonic acid) (PANI:PAAMPSA) are deposited onto a p-Si/SiO2 chip using the layer-by-layer technique (LbL). Two different enzymes (urease and penicillinase) are separately immobilized on top of a five-bilayer stack of the PAH:GO/PANI:PAAMPSA-modified EIS chip, forming a biosensor for detection of urea and penicillin, respectively. Electrochemical characterization is performed by constant capacitance (ConCap) measurements, and the film morphology is characterized by atomic force microscopy (AFM) and scanning electron microscopy (SEM). An increase in the average sensitivity of the modified biosensors (EIS–nanofilm–enzyme) of around 15% is found in relation to sensors, only carrying the enzyme but without the nanofilm (EIS–enzyme). In this sense, the nanofilm acts as a stable bioreceptor onto the EIS chip improving the output signal in terms of sensitivity and stability.
KW  - capacitive electrolyte–insulator–semiconductor sensors
KW  - graphene oxide
KW  - layer-by-layer technique
KW  - nanomaterials
KW  - polyaniline
Y1  - 2021
U6  - http://dx.doi.org/10.1002/pssa.202000747
SN  - 1862-6319
N1  - Corresponding author: José R. Siqueira Jr & Michael J. Schöning
VL  - 218
IS  - 13
SP  - 1
EP  - 9
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Keusgen, Michael
A1  - Jünger, Martina
A1  - Krest, Ingo
A1  - Schöning, Michael Josef
T1  - Biosensoric detection of the cysteine sulphoxide alliin
JF  - Sensors and Actuators B. 95 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 297
EP  - 302
ER  - 
TY  - JOUR
A1  - Keusgen, M.
A1  - Jünger, M.
A1  - Schöning, Michael Josef
T1  - Biosensoric detection of the cysteine sulphoxide alliin
JF  - Book of abstracts / ed. by J. Saneistr.
Y1  - 2002
SN  - 80-01-02576-4
N1  - Eurosensors ; (16, 2002, Praha)
SP  - 1175
EP  - 1178
PB  - Czech Technical University, Faculty of Electrical Engineering, Department of Measurement
CY  - Prague
ER  - 
TY  - JOUR
A1  - Paczkowski, Sebastian
A1  - Weißbecker, Bernhard
A1  - Schöning, Michael Josef
A1  - Schütz, Stefan
T1  - Biosensors on the Basis of Insect Olfaction
JF  - Insect biotechnology / Andreas Vilcinskas, ed.
Y1  - 2011
SN  - 978-90-481-9640-1
N1  - Biologically-inspired system ; 2
SP  - 225
EP  - 240
PB  - Springer
CY  - Dordrecht [u.a.]
ER  - 
TY  - JOUR
A1  - Ribitsch, D.
A1  - Karl, W.
A1  - Birner-Gruenberger, R.
A1  - Gruber, K.
A1  - Eiteljoerg, I.
A1  - Remler, P.
A1  - Wieland, S.
A1  - Siegert, Petra
A1  - Maurer, Karl-Heinz
A1  - Schwab, H.
T1  - C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli
JF  - Journal of biotechnology
N2  - Recently, a new alkaline protease named HP70 showing highest homology to extracellular serine proteases of Stenotrophomonas maltophilia and Xanthomonas campestris was found in the course of a metagenome screening for detergent proteases (Niehaus et al., submitted for publication). Attempts to efficiently express the enzyme in common expression hosts had failed. This study reports on the realization of overexpression in Escherichia coli after structural modification of HP70. Modelling of HP70 resulted in a two-domain structure, comprising the catalytic domain and a C-terminal domain which includes about 100 amino acids. On the basis of the modelled structure the enzyme was truncated by deletion of most of the C-terminal domain yielding HP70-C477.

This structural modification allowed effective expression of active enzyme using E. coli BL21-Gold as the host. Specific activity of HP70-C477 determined with suc-l-Ala-l-Ala-l-Pro-l-Phe-p-nitroanilide as the substrate was 30 ± 5 U/mg compared to 8 ± 1 U/mg of the native enzyme. HP70-C477 was most active at 40 °C and pH 7–11; these conditions are prerequisite for a potential application as detergent enzyme. Determination of kinetic parameters at 40 °C and pH = 9.5 resulted in KM = 0.23 ± 0.01 mM and kcat = 167.5 ± 3.6 s⁻¹. MS-analysis of peptide fragments obtained from incubation of HP70 and HP70-C477 with insulin B indicated that the C-terminal domain influences the cleavage preferences of the enzyme. Washing experiments confirmed the high potential of HP70-C477 as detergent protease.
Y1  - 2010
U6  - http://dx.doi.org/10.1016/j.jbiotec.2010.09.947
SN  - 1873-4863 (E-Journal); 0168-1656 (Print)
VL  - 150
IS  - 3
SP  - 408
EP  - 416
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Kirchner, Patrick
A1  - Reisert, Steffen
A1  - Schöning, Michael Josef
T1  - Calorimetric gas sensors for hydrogen peroxide monitoring in aseptic food processes
T2  - Gas sensing fundamentals. (Springer Series on Chemical Sensors and Biosensors ; 15)
N2  - For the sterilisation of aseptic food packages it is taken advantage of the microbicidal properties of hydrogen peroxide (H2O2). Especially, when applied in vapour phase, it has shown high potential of microbial inactivation. In addition, it offers a high environmental compatibility compared to other chemical sterilisation agents, as it decomposes into oxygen and water, respectively. Due to a lack in sensory detection possibilities, a continuous monitoring of the H2O2 concentration was recently not available. Instead, the sterilisation efficacy is validated using microbiological tests. However, progresses in the development of calorimetric gas sensors during the last 7 years have made it possible to monitor the H2O2 concentration during operation. This chapter deals with the fundamentals of calorimetric gas sensing with special focus on the detection of gaseous hydrogen peroxide. A sensor principle based on a calorimetric differential set-up is described. Special emphasis is given to the sensor design with respect to the operational requirements under field conditions. The state-of-the-art regarding a sensor set-up for the on-line monitoring and secondly, a miniaturised sensor for in-line monitoring are summarised. Furthermore, alternative detection methods and a novel multi-sensor system for the characterisation of aseptic sterilisation processes are described.
KW  - Calorimetric gas sensor
KW  - Hydrogen peroxide
KW  - Multi-sensor system
Y1  - 2014
SN  - 978-3-642-54518-4 (Print) ; 978-3-642-54519-1 (Online)
U6  - http://dx.doi.org/10.1007/5346_2013_51
SP  - 279
EP  - 309
PB  - Springer
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Mourzina, Y. G.
A1  - Schubert, J.
A1  - Zander, W.
A1  - Legin, A.
A1  - Vlasov, Y. G.
A1  - Lüth, H.
T1  - Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors?
JF  - Sensors and Actuators B. 78 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
N1  - Selected Papers form Eurosensors XIV
SP  - 273
EP  - 278
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Mourzina, Y. G.
A1  - Schubert, J.
A1  - Zander, W.
A1  - Legin, A.
A1  - Vlasov, Y. G.
A1  - Lüth, H.
T1  - Can pulsed laser deposition serve as an advanced technique in fabricating chemical sensors?
JF  - Proceedings : Copenhagen, Denmark, 27 - 30 August 2000 / [ed.: R. de Reus ...]
Y1  - 2000
SN  - 87-89935-50-0
N1  - Eurosensors ; (14, 2000, København) ; Eurosensors ; (14 : ; 2000.08.27-30 : ; Copenhagen) ; European Conference on Solid-State Transducers ; (14 : ; 2000.08.27-30 : ; Copenhagen)
SP  - 615
EP  - 618
PB  - MIC, Mikroelektronik Centret
CY  - Lyngby, Denmark
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Schöning, Michael Josef
T1  - Capacitance–voltage and impedance characteristics of field-effect EIS sensors functionalised with polyelectrolyte multilayers
JF  - IRBM. 29 (2008), H. 2-3
Y1  - 2008
SN  - 1959-0318
SP  - 149
EP  - 154
ER  - 
TY  - JOUR
A1  - Abouzar, Maryam H.
A1  - Werner, Moritz
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
T1  - Capacitance–voltage and impedance-spectroscopy characteristics of nanoplate EISOI capacitors
JF  - Physica status solidi (a) : applications and material science. 208 (2011), H. 6
Y1  - 2011
SN  - 1862-6319
SP  - 1327
EP  - 1332
PB  - Wiley-VCH
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Abouzar, Maryam H.
A1  - Poghossian, Arshak
A1  - Siqueira, José R. Jr.
A1  - Oliveira, Osvaldo N. Jr.
A1  - Moritz, Werner
A1  - Schöning, Michael Josef
T1  - Capacitive electrolyte-insulator-semiconductor structures functionalised with a polyelectrolyte/enzyme multilayer: New strategy for enhanced field-effect biosensing
JF  - Physica Status Solidi (A). 207 (2010), H. 4
Y1  - 2010
SN  - 1862-6300
N1  - Special Issue: Engineering of Functional Interfaces EnFI 2009
SP  - 884
EP  - 890
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Wenmackers, Sylvia
A1  - Janssens, Stoffel D.
A1  - Haenen, Ken
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films
JF  - Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.]
Y1  - 2010
N1  - MRS Proceedings Volume 1203 paper 1203-J17-31 ; Mater. Res. Soc. Sympos. Proc. Vol 1203 (2010) ; Materials Research Society
SP  - 1
EP  - 6
ER  - 
TY  - JOUR
A1  - Jablonski, Melanie
A1  - Poghossian, Arshak
A1  - Severin, Robin
A1  - Keusgen, Michael
A1  - Wege, Christian
A1  - Schöning, Michael Josef
T1  - Capacitive Field-Effect Biosensor Studying Adsorption of Tobacco Mosaic Virus Particles
JF  - Micromachines
N2  - Plant virus-like particles, and in particular, tobacco mosaic virus (TMV) particles, are increasingly being used in nano- and biotechnology as well as for biochemical sensing purposes as nanoscaffolds for the high-density immobilization of receptor molecules. The sensitive parameters of TMV-assisted biosensors depend, among others, on the density of adsorbed TMV particles on the sensor surface, which is affected by both the adsorption conditions and surface properties of the sensor. In this work, Ta₂O₅-gate field-effect capacitive sensors have been applied for the label-free electrical detection of TMV adsorption. The impact of the TMV concentration on both the sensor signal and the density of TMV particles adsorbed onto the Ta₂O₅-gate surface has been studied systematically by means of field-effect and scanning electron microscopy methods. In addition, the surface density of TMV particles loaded under different incubation times has been investigated. Finally, the field-effect sensor also demonstrates the label-free detection of penicillinase immobilization as model bioreceptor on TMV particles.
KW  - capacitive field-effect sensor
KW  - plant virus detection
KW  - tobacco mosaic virus (TMV)
KW  - TMV adsorption
KW  - Ta₂O₅ gate
Y1  - 2021
U6  - http://dx.doi.org/10.3390/mi12010057
VL  - 12
IS  - 1
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Capacitive field-effect eis chemical sensors and biosensors: A status report
JF  - Sensors
N2  - Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.
Y1  - 2020
U6  - http://dx.doi.org/10.3390/s20195639
SN  - 1424-8220
VL  - 20
IS  - 19
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Buniatyan, Vahe V.
A1  - Matirosyan, N.
A1  - Abouzar, Maryam H.
A1  - Schubert, J.
A1  - Zander, W.
A1  - Gevorgian, S.
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
T1  - Capacitive field-effect pH sensor based on an electrolyte-ferroelectric-insulator-semiconductor structure
JF  - SENSOR 2009 : : 14th International Conference on Sensors, Technologies, Electronics and Applications; Nürnberg, Germany, 26 - 28 May 2009; proceedings; [part of] Sensor + Test Conference 2009 / AMA, Fachverband für Sensorik e.V
Y1  - 2009
SN  - 9783981099355
N1  - AMA, Fachverband für Sensorik ; Sensor International Conference ; (14 : ; 2009.05.26-28 : ; Nürnberg)
SP  - 317
EP  - 322
PB  - AMA Service
CY  - Wunstorf
ER  - 
TY  - JOUR
A1  - Jablonski, Melanie
A1  - Münstermann, Felix
A1  - Nork, Jasmina
A1  - Molinnus, Denise
A1  - Muschallik, Lukas
A1  - Bongaerts, Johannes
A1  - Wagner, Torsten
A1  - Keusgen, Michael
A1  - Siegert, Petra
A1  - Schöning, Michael Josef
T1  - Capacitive field‐effect biosensor applied for the detection of acetoin in alcoholic beverages and fermentation broths
JF  - physica status solidi (a) applications and materials science
N2  - An acetoin biosensor based on a capacitive electrolyte–insulator–semiconductor (EIS) structure modified with the enzyme acetoin reductase, also known as butane-2,3-diol dehydrogenase (Bacillus clausii DSM 8716ᵀ), is applied for acetoin detection in beer, red wine, and fermentation broth samples for the first time. The EIS sensor consists of an Al/p-Si/SiO₂/Ta₂O₅ layer structure with immobilized acetoin reductase on top of the Ta₂O₅ transducer layer by means of crosslinking via glutaraldehyde. The unmodified and enzyme-modified sensors are electrochemically characterized by means of leakage current, capacitance–voltage, and constant capacitance methods, respectively.
KW  - acetoin
KW  - acetoin reductase
KW  - alcoholic beverages
KW  - biosensors
KW  - capacitive field-effect sensors
Y1  - 2021
U6  - http://dx.doi.org/10.1002/pssa.202000765
SN  - 1862-6319
VL  - 218
IS  - 13
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Kurowski, A.
A1  - Thust, M.
A1  - Kordos, P.
A1  - Schultze, J. W.
A1  - Lüth, H.
T1  - Capacitive microsensors for biochemical sensing on porous silicon technology
JF  - Sensors and Actuators B. 64 (2000), H. 1-3
Y1  - 2000
SN  - 0925-4005
SP  - 59
EP  - 64
ER  -