TY - CHAP A1 - Jung, Alexander A1 - Staat, Manfred ED - Erni, Daniel T1 - Computing olympic gold: Ski jumping as an example T2 - 1st YRA MedTech Symposium 2016 : April 8th / 2016 / University of Duisburg-Essen Y1 - 2016 SN - 978-3-940402-06-6 U6 - https://doi.org/10.17185/duepublico/40821 SP - 54 EP - 55 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - JOUR A1 - Wulfhorst, Helene A1 - Duwe, Anna-Maria A1 - Merseburg, Johannes A1 - Tippkötter, Nils T1 - Compositional analysis of pretreated (beech) wood using differential scanning calorimetry and multivariate data analysis JF - Tetrahedron N2 - The composition of plant biomass varies depending on the feedstock and pre-treatment conditions and influences its processing in biorefineries. In order to ensure optimal process conditions, the quantitative proportion of the main polymeric components of the pre-treated biomass has to be determined. Current standard procedures for biomass compositional analysis are complex, the measurements are afflicted with errors and therefore often not comparable. Hence, new powerful analytical methods are urgently required to characterize biomass. In this contribution, Differential Scanning Calorimetry (DSC) was applied in combination with multivariate data analysis (MVA) to detect the cellulose content of the plant biomass pretreated by Liquid Hot Water (LHW) and Organosolv processes under various conditions. Unlike conventional techniques, the developed analytic method enables the accurate quantification of monosaccharide content of the plant biomass without any previous sample preparation. It is easy to handle and avoids errors in sample preparation. Y1 - 2016 U6 - https://doi.org/10.1016/j.tet.2016.04.029 VL - 72 IS - 46 SP - 7329 EP - 7334 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Funke, Harald A1 - Beckmann, Nils A1 - Keinz, Jan A1 - Abanteriba, Sylvester T1 - Comparison of Numerical Combustion Models for Hydrogen and Hydrogen-Rich Syngas Applied for Dry-Low-NOx-Micromix-Combustion JF - ASME Turbo Expo 2016: Turbomachinery Technical Conference and Exposition Volume 4A: Combustion, Fuels and Emissions Seoul, South Korea, June 13–17, 2016 N2 - The Dry-Low-NOₓ (DLN) Micromix combustion technology has been developed as low emission combustion principle for industrial gas turbines fueled with hydrogen or syngas. The combustion process is based on the phenomenon of jet-in-crossflow-mixing. Fuel is injected perpendicular into the air-cross-flow and burned in a multitude of miniaturized, diffusion-like flames. The miniaturization of the flames leads to a significant reduction of NOₓ emissions due to the very short residence time of reactants in the flame. In the Micromix research approach, CFD analyses are validated towards experimental results. The combination of numerical and experimental methods allows an efficient design and optimization of DLN Micromix combustors concerning combustion stability and low NOₓ emissions. The paper presents a comparison of several numerical combustion models for hydrogen and hydrogen-rich syngas. They differ in the complexity of the underlying reaction mechanism and the associated computational effort. For pure hydrogen combustion a one-step global reaction is applied using a hybrid Eddy-Break-up model that incorporates finite rate kinetics. The model is evaluated and compared to a detailed hydrogen combustion mechanism derived by Li et al. including 9 species and 19 reversible elementary reactions. Based on this mechanism, reduction of the computational effort is achieved by applying the Flamelet Generated Manifolds (FGM) method while the accuracy of the detailed reaction scheme is maintained. For hydrogen-rich syngas combustion (H₂-CO) numerical analyses based on a skeletal H₂/CO reaction mechanism derived by Hawkes et al. and a detailed reaction mechanism provided by Ranzi et al. are performed. The comparison between combustion models and the validation of numerical results is based on exhaust gas compositions available from experimental investigation on DLN Micromix combustors. The conducted evaluation confirms that the applied detailed combustion mechanisms are able to predict the general physics of the DLN-Micromix combustion process accurately. The Flamelet Generated Manifolds method proved to be generally suitable to reduce the computational effort while maintaining the accuracy of detailed chemistry. Especially for reaction mechanisms with a high number of species accuracy and computational effort can be balanced using the FGM model. Y1 - 2016 SN - 978-0-7918-4975-0 U6 - https://doi.org/10.1115/GT2016-56430 PB - ASME CY - New York, NY ER - TY - CHAP A1 - Finger, Felix T1 - Comparative Performance and Benefit Assessment of VTOL and CTOL UAVs T2 - Deutscher Luft- und Raumfahrtkongress (DLRK) 2016, 13.-15.9.2016 Y1 - 2016 ER - TY - JOUR A1 - Zhang, Jin A1 - Heimbach, Tycho A1 - Scheer, Nico A1 - Barve, Avantika A1 - Li, Wenkui A1 - Lin, Wen A1 - He, Handan T1 - Clinical Exposure Boost Predictions by Integrating Cytochrome P450 3A4–Humanized Mouse Studies With PBPK Modeling JF - Journal of Pharmaceutical Sciences N2 - NVS123 is a poorly water-soluble protease 56 inhibitor in clinical development. Data from in vitro hepatocyte studies suggested that NVS123 is mainly metabolized by CYP3A4. As a consequence of limited solubility, NVS123 therapeutic plasma exposures could not be achieved even with high doses and optimized formulations. One approach to overcome NVS123 developability issues was to increase plasma exposure by coadministrating it with an inhibitor of CYP3A4 such as ritonavir. A clinical boost effect was predicted by using physiologically based pharmacokinetic (PBPK) modeling. However, initial boost predictions lacked sufficient confidence because a key parameter, fraction of drug metabolized by CYP3A4 (ƒₘCYP3A4), could not be estimated with accuracy on account of disconnects between in vitro and in vivo preclinical data. To accurately estimate ƒₘCYP3A4 in human, an in vivo boost effect study was conducted using CYP3A4-humanized mouse model which showed a 33- to 56-fold exposure boost effect. Using a top-down approach, human ƒₘCYP3A4 for NVS123 was estimated to be very high and included in the human PBPK modeling to support subsequent clinical study design. The combined use of the in vivo boost study in CYP3A4-humanized mouse model mice along with PBPK modeling accurately predicted the clinical outcome and identified a significant NVS123 exposure boost (∼42-fold increase) with ritonavir. Y1 - 2016 U6 - https://doi.org/doi.org/10.1016/j.xphs.2016.01.021 SN - 0022-3549 VL - Volume 105 IS - Issue 4 SP - 1398 EP - 1404 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Weber, Tobias A1 - Tellis, Jane J. A1 - Duhovic, Miro T1 - Characterization of tool-part-interaction an interlaminar friction for manufacturing process simulation T2 - ECCM 17, 17th European Conference on Composite Materials, München, DE, Jun 26-30, 2016 Y1 - 2016 SN - 978-3-00-053387-7 SP - 1 EP - 7 ER - TY - CHAP A1 - Roth, J. A1 - Möhring, S. A1 - Tippkötter, Nils T1 - Characterization and evaluation of lignocellulosic biomass 130 hydrolysates for ABE fermentation T2 - New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany Y1 - 2016 SP - 130 PB - DECHEMA CY - Frankfurt am Main ER - TY - JOUR A1 - Ayed, Anis Haj A1 - Kusterer, Karsten A1 - Funke, Harald A1 - Keinz, Jan T1 - CFD Based Improvement of the DLN Hydrogen Micromix Combustion Technology at Increased Energy Densities JF - American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS) N2 - Combined with the use of renewable energy sources for its production, Hydrogen represents a possible alternative gas turbine fuel within future low emission power generation. Due to the large difference in the physical properties of Hydrogen compared to other fuels such as natural gas, well established gas turbine combustion systems cannot be directly applied for Dry Low NOx (DLN) Hydrogen combustion. Thus, the development of DLN combustion technologies is an essential and challenging task for the future of Hydrogen fuelled gas turbines. The DLN Micromix combustion principle for hydrogen fuel has been developed to significantly reduce NOx-emissions. This combustion principle is based on cross-flow mixing of air and gaseous hydrogen which reacts in multiple miniaturized diffusion-type flames. The major advantages of this combustion principle are the inherent safety against flash-back and the low NOx-emissions due to a very short residence time of reactants in the flame region of the micro-flames. The Micromix Combustion technology has been already proven experimentally and numerically for pure Hydrogen fuel operation at different energy density levels. The aim of the present study is to analyze the influence of different geometry parameter variations on the flame structure and the NOx emission and to identify the most relevant design parameters, aiming to provide a physical understanding of the Micromix flame sensitivity to the burner design and identify further optimization potential of this innovative combustion technology while increasing its energy density and making it mature enough for real gas turbine application. The study reveals great optimization potential of the Micromix Combustion technology with respect to the DLN characteristics and gives insight into the impact of geometry modifications on flame structure and NOx emission. This allows to further increase the energy density of the Micromix burners and to integrate this technology in industrial gas turbines. Y1 - 2016 SN - 2313-4402 VL - 26 IS - 3 SP - 290 EP - 303 PB - GSSRR ER - TY - JOUR A1 - Schopp, Christoph A1 - Doll, Timo A1 - Gräser, Ulrich A1 - Harzheim, Thomas A1 - Heuermann, Holger A1 - Kling, Rainer A1 - Marso, Michael T1 - Capacitively Coupled High-Pressure Lamp Using Coaxial Line Networks JF - IEEE Transactions on Microwave Theory and Techniques N2 - This paper describes the development of a capacitively coupled high-pressure lamp with input power between 20 and 43 W at 2.45 GHz, using a coaxial line network. Compared with other electrodeless lamp systems, no cavity has to be used and a reduction in the input power is achieved. Therefore, this lamp is an alternative to the halogen incandescent lamp for domestic lighting. To serve the demands of domestic lighting, the filling of the lamp is optimized over all other resulting requirements, such as high efficacy at low induced powers and fast startups. A workflow to develop RF-driven plasma applications is presented, which makes use of the hot S-parameter technique. Descriptions of the fitting process inside a circuit and FEM simulator are given. Results of the combined ignition and operation network from simulations and measurements are compared. An initial prototype is built and measurements of the lamp's lighting properties are presented along with an investigation of the efficacy optimizations using large signal amplitude modulation. With this lamp, an efficacy of 135 lmW -1 is achieved. Y1 - 2016 U6 - https://doi.org/10.1109/TMTT.2016.2600326 SN - 0018-9480 VL - 64 IS - 10 SP - 3363 EP - 3368 PB - IEEE CY - New York, NY ER - TY - JOUR A1 - Belavy, Daniel L. A1 - Albracht, Kirsten A1 - Bruggemann, Gert-Peter A1 - Vergroesen, Pieter-Paul A. A1 - Dieen, Jaap H. van T1 - Can exercise positively influence the intervertebral disc? JF - Sports Medicine N2 - To better understand what kinds of sports and exercise could be beneficial for the intervertebral disc (IVD), we performed a review to synthesise the literature on IVD adaptation with loading and exercise. The state of the literature did not permit a systematic review; therefore, we performed a narrative review. The majority of the available data come from cell or whole-disc loading models and animal exercise models. However, some studies have examined the impact of specific sports on IVD degeneration in humans and acute exercise on disc size. Based on the data available in the literature, loading types that are likely beneficial to the IVD are dynamic, axial, at slow to moderate movement speeds, and of a magnitude experienced in walking and jogging. Static loading, torsional loading, flexion with compression, rapid loading, high-impact loading and explosive tasks are likely detrimental for the IVD. Reduced physical activity and disuse appear to be detrimental for the IVD. We also consider the impact of genetics and the likelihood of a ‘critical period’ for the effect of exercise in IVD development. The current review summarises the literature to increase awareness amongst exercise, rehabilitation and ergonomic professionals regarding IVD health and provides recommendations on future directions in research. KW - Intradiscal Pressure KW - Annulus Fibrosus KW - Disc Degeneration KW - Nucleus Pulposus KW - Intervertebral Disc Y1 - 2016 U6 - https://doi.org/10.1007/s40279-015-0444-2 SN - 1179-2035 VL - 46 IS - 4 SP - 473 EP - 485 PB - Springer CY - Berlin ER - TY - JOUR A1 - Becker, Jörg A1 - Delfmann, Patrick A1 - Dietrich, Hanns-Alexander A1 - Steinhorst, Matthias A1 - Eggert, Mathias T1 - Business Process Compliance Checking — Applying and Evaluating a Generic Pattern Matching Approach for Conceptual Models in the Financial Sector JF - Information Systems Frontiers N2 - Given the strong increase in regulatory requirements for business processes the management of business process compliance becomes a more and more regarded field in IS research. Several methods have been developed to support compliance checking of conceptual models. However, their focus on distinct modeling languages and mostly linear (i.e., predecessor-successor related) compliance rules may hinder widespread adoption and application in practice. Furthermore, hardly any of them has been evaluated in a real-world setting. We address this issue by applying a generic pattern matching approach for conceptual models to business process compliance checking in the financial sector. It consists of a model query language, a search algorithm and a corresponding modelling tool prototype. It is (1) applicable for all graph-based conceptual modeling languages and (2) for different kinds of compliance rules. Furthermore, based on an applicability check, we (3) evaluate the approach in a financial industry project setting against its relevance for decision support of audit and compliance management tasks. Y1 - 2016 U6 - https://doi.org/10.1007/s10796-014-9529-y SN - 1572-9419 VL - 18 IS - 2 SP - 359 EP - 405 PB - Springer CY - Berlin ER - TY - JOUR A1 - Olbertz, Klaus T1 - Bundesregierung beschließt Flexi-Rente JF - NWB - Steuer- und Wirtschaftsrecht N2 - Das Bundeskabinett hat sich am 14.9.2016 mit der sog. Flexi-Rente befasst und eine sog. Formulierungshilfe verabschiedet, der ein aus den Regierungsfraktionen des Bundestages einzubringender entsprechender Gesetzesentwurf zur „Flexibilisierung des Übergangs vom Erwerbsleben in den Ruhestand und zur Stärkung von Prävention und Rehabilitation im Erwerbsleben (Flexirentengesetz)“ folgen soll. Eine entsprechende Vorabfassung des Gesetzesentwurfs liegt bereits vor (BT-Drucks. 18/9787). Mit der Flexi-Rente sollen im Wesentlichen zwei Ziele erreicht werden: Das flexible Arbeiten bis zum Erreichen der Regelaltersgrenze soll gefördert und das Weiterarbeiten über die Regelaltersgrenze hinaus attraktiver gemacht werden. Hierfür ist eine Reihe von gesetzlichen Änderungen geplant, insbesondere im SGB VI und SGB III. Teile des Gesetzes sollen schon zum 1.1.2017 in Kraft treten. Grund genug, sich bereits jetzt einen ersten Überblick über die geplanten Neuerungen zu verschaffen. Y1 - 2018 SN - 1860-9449 IS - 42 SP - 3145 EP - 3147 ER - TY - RPRT A1 - Sansom, M. A1 - Lawson, R.M. A1 - Tucho, R. A1 - Kendrick, C. A1 - Ogden, R. A1 - Resalati, S. A1 - Garay, R. A1 - Döring, Bernd A1 - Reger, V. A1 - Gilbert, J. A1 - Heikkinen, J. A1 - Hemmila, K. T1 - Building in active thermal mass into steel structures (BATIMASS) - EUR 28166EN N2 - The main objective of the BATIMASS project was to address how the energy balance in relatively lightweight steel buildings can be improved by building in ‘active thermal mass’ (ATM) into the building fabric. This was achieved through concept design, dynamic thermal modelling and testing of a number of potentially viable systems and concepts. A significant programme of thermal simulation modelling was undertaken utilising the thermally equivalent slab (TES) concept to model the passive thermal capacity effect of profiled, composite metal floor decks. It is apparent from the modelling results that thermal mass is a highly complex phenomenon which is highly dependent upon building type, occupancy patterns, climate and many other aspects of the building design and servicing strategy. The ATM systems developed, both conceptually and for prototype testing, focussed on water-cooled composite slabs, the Cofradal floor system and the phase change material (PCM) Energain. In addition to laboratory testing of prototypes, whole building monitoring was undertaken at the Kubik building in Spain and the RWTH test building in Germany. Advanced thermal modelling was also undertaken to estimate the likely benefits of the ATM concept designs developed and for comparison with the test results. In addition to thermal testing, structural tests were conducted on composite floor specimens incorporating embedded water pipes. This Final Report presents the results of the activities carried out under this RFCS contract RFSR CT 2012 00033. The work carried out is reported in six major sections corresponding to the technical Work Packages of the project. Only summaries of the work carried out are provided in this report; all work undertaken is fully reported in the formal project deliverables. KW - industrial research KW - iron and steel industry KW - research project KW - materials technology KW - resistance of materials KW - steel KW - metal structure KW - ingot KW - building industry KW - research report Y1 - 2016 SN - 978-92-79-63176-4 U6 - https://doi.org/10.2777/25999 SN - 1831-9424 PB - Publications Office of the European Union CY - Luxembourg ER - TY - CHAP A1 - Ulke, Bernd T1 - Boden, Baugrube, Verbau T2 - Zahlentafeln für den Baubetrieb N2 - Die Lösung den Baugrund betreffender Fragestellungen beginnen i. d. R. mit der Durchführung von Baugrunderkundungen, um alle notwendigen Parameter zu erhalten, die für die Planung und Durchführung von Bauvorhaben notwendig sind. Im Folgenden werden die wichtigsten Erkundungen in Abhängigkeit der erforderlichen Güteklasse der Proben beschrieben und vorgestellt. Y1 - 2016 SN - 978-3-658-02838-1 (Online) SN - 978-3-658-02837-4 (Print) U6 - https://doi.org/10.1007/978-3-658-02838-1_10 SP - 1165 EP - 1246 PB - Springer Vieweg CY - Wiesbaden ET - 9., überarb. und aktual. Aufl. ER - TY - JOUR A1 - Kern, Alexander T1 - Blitz- und Überspannungsschutz von Kernkraftwerken - Nachweisführung der ausreichenden Sicherheit für leittechnische Einrichtungen auch bei Blitzeinschlägen mit extremen Parametern JF - Atw. International Journal for Nuclear Power N2 - Für das Auftreten extremer Wetterereignisse werden für Kernkraftwerke Eintrittshäufigkeiten für nicht mehr beherrschbare Zustände von unter 10⁻⁴/a gefordert. Dies gilt auch für die Einwirkung von Blitzeinschlägen. Die bisherige Nachweisführung zu Blitz- und Überspannungsschutz eines KKW in Deutschland ist deterministisch. In diesem Bericht werden das Vorgehen für einen entsprechenden Nachweis für leittechnische Einrichtungen der Sicherheitstechnik von KKW, der zur geforderten Zielgröße der Eintrittshäufigkeit führt. Die Ergebnisse werden zusammenfassend bewertet. Y1 - 2016 SN - 1431-5254 VL - 61 IS - 8/9 SP - 534 EP - 543 PB - Inforum CY - Berlin ER - TY - THES A1 - Föckler, Nicole T1 - Biomarker zur Prognose von Frühgeburten : ein biomedizintechnischer Ansatz Y1 - 2016 U6 - https://doi.org/10.4126/FRL01-006401575 N1 - Dissertation, Köln, Universität zu Köln, 2016 PB - Deutsche Zentralbibliothek für Medizin CY - Köln ER - TY - CHAP A1 - Kasper, Katharina A1 - Schiffels, Johannes A1 - Krafft, Simone A1 - Kuperjans, Isabel A1 - Elbers, Gereon A1 - Selmer, Thorsten T1 - Biogas Production on Demand Regulated by Butyric Acid Addition T2 - IOP Conference Series: Earth and Environmental Science. Bd. 32 Y1 - 2016 U6 - https://doi.org/10.1088/1755-1315/32/1/012009 SN - 1755-1315 N1 - ICARET 2016, International Conference on Advances in Renewable Energy and Technologies, Putrajaya, MY, Feb 23-25, 2016 VL - 32 SP - 012009/1 EP - 012009/4 ER - TY - CHAP A1 - Stollenwerk, Dominik A1 - Rieke, C. A1 - Dahmen, Markus A1 - Pieper, Martin T1 - Biogas Production Modelling : A Control System Engineering Approach T2 - IOP Conference Series: Earth and Environmental Science. Bd. 32 Y1 - 2016 U6 - https://doi.org/10.1088/1755-1315/32/1/012008 SN - 1755-1315 N1 - ICARET 2016, International Conference on Advances in Renewable Energy and Technologies, Putrajaya, MY, Feb 23-25, 2016 SP - 012008/1 EP - 012008/4 ER - TY - CHAP A1 - Martin, Joachim T1 - Betriebsorganisation T2 - Zahlentafeln für den Baubetrieb N2 - Das Kapitel behandelt, ausgehend von Begriffen und Aufgaben der Betriebsorganisation, die Aufbau- und Ablauforganisation der Bauunternehmung sowie die Gestaltung einer Projekt-organisation. Es folgt eine Darstellung der Managementsysteme für Qualität, Umwelt und Arbeitsschutz, die sich zunehmend als sog. integrierte Managementsysteme (IMS) auch in Bauunternehmen etablieren. Grundlagen des Personalmanagements und des betrieblichen Rechnungswesens, die für eine(n) Baubetriebler(in) relevant sein können, ergänzen das Kap. Betriebsorganisation. Den Abschluss bilden Hinweise zum Berichtswesen der Baustelle. Y1 - 2016 SN - 978-3-658-02838-1 (Online) SN - 978-3-658-02837-4 (Print) U6 - https://doi.org/10.1007/978-3-658-02838-1_12 SP - 1297 EP - 1389 PB - Springer Vieweg CY - Wiesbaden ET - 9., überarb. und aktual. Aufl. ER - TY - CHAP A1 - Schlösser, Karl Helmut T1 - Bauwirtschaft und Baurecht T2 - Zahlentafeln für den Baubetrieb N2 - Die Leistungen der Bauwirtschaft und deren wirtschaftliche Bedeutung in Deutschland werden anhand einer Vielzahl statistischer Daten verdeutlicht. Die im Vergleich zu anderen Wirtschaftsbereichen auftretenden branchenspezifischen Besonderheiten der Bauwirtschaft werden anhand von verschiedenen Kriterien herausgearbeitet. Das Zusammenspiel der einzelnen Akteure des Sektors und die dabei sich ergebenden bzw. zu beachtenden Rechts- und Vertragsgrundlagen werden dargestellt. Aufgrund der meist erheblichen Höhe des eingesetzten Kapitals aufseiten der Auftraggeber, aber auch seitens der Bauunternehmen während der Bauausführung sowie der besonderen Verantwortung der Beratenden Ingenieure werden auch notwendige Formen der Risikoabsicherungen und der in der Branche üblichen und teilweise vorgeschriebenen Versicherungsmöglichkeiten angesprochen. Intensive Beachtung finden auch die Auswirkungen des Öffentlichen Baurechts (Baugesetzbuch, Bauordnung NRW, Baunutzungsverordnung) auf Planung, Bau und Betrieb baulicher Anlagen und der dabei verwendeten Bauprodukte. Y1 - 2016 SN - 978-3-658-02838-1 (Online) SN - 978-3-658-02837-4 (Print) U6 - https://doi.org/10.1007/978-3-658-02838-1_4 SP - 179 EP - 421 PB - Springer Vieweg CY - Wiesbaden ET - 9., überarb. und aktual. Aufl. ER - TY - CHAP A1 - Krause, Thomas A1 - Oettel, Britta T1 - Baumaschinen T2 - Zahlentafeln für den Baubetrieb N2 - Die Leistungsermittlung und Bemessung von Baumaschinen für die folgenden Bereiche werden bearbeitet: Maschinen für den Betonbau, Hebezeuge, Maschinen für den Erdbau, Straßenbaumaschinen, Rückbaugeräte und Elemente der Baustelleneinrichtung Y1 - 2016 SN - 978-3-658-02838-1 (Online) SN - 978-3-658-02837-4 (Print) U6 - https://doi.org/10.1007/978-3-658-02838-1_9 SP - 1069 EP - 1163 PB - Springer Vieweg CY - Wiesbaden ET - 9., überarb. und aktual. Aufl. ER - TY - CHAP A1 - Schlösser, Karl Helmut T1 - Baukosten und Finanzierung T2 - Zahlentafeln für den Baubetrieb Y1 - 2016 SN - 978-3-658-02838-1 (Online) SN - 978-3-658-02837-4 (Print) U6 - https://doi.org/10.1007/978-3-658-02838-1_5 SP - 423 EP - 634 PB - Springer Vieweg CY - Wiesbaden ET - 9., überarb. und aktual. Aufl. ER - TY - CHAP A1 - Krause, Thomas T1 - Bauabrechnung und Mengenermittlung T2 - Zahlentafeln für den Baubetrieb N2 - In diesem Kapitel werden die Abrechnungsvorschriften wichtiger ATV kurz, aber umfassend zusammengestellt. Einigen Abrechnungsbestimmungen für Einzelleistungen, die keine Nebenleistungen sind ((siehe DIN 18299 und Abschnitt 4 der jeweiligen ATV), sind mit aufgenommen worden; die ATV enthalten jedoch weitergehende Festlegungen über Nebenleistungen und Besondere Leistungen. Im Anschluss folgen Hinweise zu den Toleranzen im Hochbau sowie im Straßenbau. Y1 - 2016 SN - 978-3-658-02838-1 (Online) SN - 978-3-658-02837-4 (Print) U6 - https://doi.org/10.1007/978-3-658-02838-1_7 SP - 963 EP - 1027 PB - Springer Vieweg CY - Wiesbaden ET - 9., überarb. und aktual. Aufl. ER - TY - GEN A1 - Wulfhorst, H. A1 - Merseburg, J. A1 - Tippkötter, Nils T1 - Batteriekomponenten aus nachwachsenden Rohstoffen T2 - Chemie Ingenieur Technik N2 - In diesem Beitrag geht es um die Integration von Stoffströmen einer Lignocellulose-Bioraffinerie in Verfahren zur Batterieherstellung. Pflanzliche Reststoffe aus der Biokraftstoffherstellung wie Lignin sollen zur Herstellung neuer Batteriematerialien verwendet werden. Hierbei wird das Lignin als Matrix für die vorgraphitischen C-haltigen Einlagerungsverbindungen in den Elektroden genutzt. Die Si-C-Komposite werden durch das Einbetten von Si in eine Ligninmatrix mit anschließender Carbonisierung hergestellt. Das Lignin hierfür wird durch die sequentielle hydrothermale Vorbehandlung von Buchenholz bei variablen Bedingungen gewonnen und mit Si-Nanopartikel sowie als Referenz ohne Si-Nanopartikel gefällt. Die Ergebnisse zeigen, dass die sequenzielle Vorbehandlung höhere Ausbeuten im Vergleich zum LHW- oder Organosolv-Aufschluss liefert. Um eine Anode herzustellen, wurde das resultierende Si–C-Kompositmaterial carbonisiert, auf einen Stromsammler aufgetragen und elektro-chemisch charakterisiert. Der Einfluss der Vorbehandlungsschritte auf den Herstellungsprozess und die ökonomische Bewertung des untersuchten Bioraffinerie-Prozesses wurde mithilfe eines Stoffstrommodells analysiert. Y1 - 2016 U6 - https://doi.org/10.1002/cite.201650333 SN - 0009-286X SN - 1522-2640 (eISSN) N1 - ProcessNet-Jahrestagung 2016 und 32. DECHEMA-Jahrestagung der Biotechnologen 2016, 12. - 15. September 2016, Eurogress Aachen VL - 88 IS - 9 SP - 1234 EP - 1235 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Kessler, Julia A1 - Balc, Nicolae A1 - Gebhardt, Andreas T1 - Basic research on lattice structures focused on the strut shape and welding beads T2 - Physics Procedia Y1 - 2016 U6 - https://doi.org/10.1016/j.phpro.2016.08.086 SN - 1875-3884 N1 - Laser Assisted Net Shape Engineering 9th International Conference on Photonic Technologies Proceedings of the LANE 2016 VL - Vol. 83 SP - 833 EP - 838 ER - TY - JOUR A1 - Neu, Eugen A1 - Janser, Frank A1 - Khatibi, Akbar A. A1 - Orifici, Adrian C. T1 - Automated modal parameter-based anomaly detection under varying wind excitation JF - Structural Health Monitoring N2 - Wind-induced operational variability is one of the major challenges for structural health monitoring of slender engineering structures like aircraft wings or wind turbine blades. Damage sensitive features often show an even bigger sensitivity to operational variability. In this study a composite cantilever was subjected to multiple mass configurations, velocities and angles of attack in a controlled wind tunnel environment. A small-scale impact damage was introduced to the specimen and the structural response measurements were repeated. The proposed damage detection methodology is based on automated operational modal analysis. A novel baseline preparation procedure is described that reduces the amount of user interaction to the provision of a single consistency threshold. The procedure starts with an indeterminate number of operational modal analysis identifications from a large number of datasets and returns a complete baseline matrix of natural frequencies and damping ratios that is suitable for subsequent anomaly detection. Mahalanobis distance-based anomaly detection is then applied to successfully detect the damage under varying severities of operational variability and with various degrees of knowledge about the present operational conditions. The damage detection capabilities of the proposed methodology were found to be excellent under varying velocities and angles of attack. Damage detection was less successful under joint mass and wind variability but could be significantly improved through the provision of the currently encountered operational conditions. Y1 - 2016 U6 - https://doi.org/10.1177/1475921716665803 SN - 1475-9217 VL - 15 IS - 6 SP - 1 EP - 20 PB - Sage CY - London ER - TY - GEN A1 - Olbertz, Klaus T1 - Ausschluss von Sozialplanabfindung und Klageverzichtsprämie T2 - Gesellschafts- und Wirtschaftsrecht : GWR Y1 - 2018 SN - 1868-1816 N1 - Anm. zu BAG: Entscheidungsbesprechung zum Urteil v. 08.12.2015 - 1 AZR 595/14 SP - 391 EP - 391 ER - TY - CHAP A1 - Butenweg, Christoph A1 - Roeser, W. T1 - Auslegung von Bauwerken gegen Erdbeben - Rechenbeispiele T2 - Stahlbetonbau aktuell 2016 : Praxishandbuch / herausgegeben von: Prof. Dr.-Ing. Josef Hegger, Prof. Dr.-Ing. habil. Peter Mark Y1 - 2016 SN - 978-3-410-25202-3 (Print) ; 978-3-410-25203-0 (E-Book) PB - Beuth Verlag GmbH CY - Berlin ; Wien ; Zürich ER - TY - CHAP A1 - Butenweg, Christoph A1 - Kubalski, Thomas A1 - Marinkovic, Marko A1 - Pfetzing, Thomas A1 - Ismail, Mohammed A1 - Fehling, Ekkehard T1 - Ausfachungen aus Ziegelmauerwerk T2 - Mauerwerk-Kalender 2016: Baustoffe, Sanierung, Eurocode-Praxis Y1 - 2016 SN - 978-3-433-03131-5 PB - Ernst & Sohn CY - Berlin ER - TY - JOUR A1 - Infantino, Angelo A1 - Paulßen, Elisabeth A1 - Mostacci, Domiziano A1 - Schaffer, Paul A1 - Trinczek, Michael A1 - Hoehr, Cornelia T1 - Assessment of the production of medical isotopes using the Monte Carlo code FLUKA: Simulations against experimental measurements JF - Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms N2 - The Monte Carlo code FLUKA is used to simulate the production of a number of positron emitting radionuclides, ¹⁸F, ¹³N, ⁹⁴Tc, ⁴⁴Sc, ⁶⁸Ga, ⁸⁶Y, ⁸⁹Zr, ⁵²Mn, ⁶¹Cu and ⁵⁵Co, on a small medical cyclotron with a proton beam energy of 13 MeV. Experimental data collected at the TR13 cyclotron at TRIUMF agree within a factor of 0.6 ± 0.4 with the directly simulated data, except for the production of ⁵⁵Co, where the simulation underestimates the experiment by a factor of 3.4 ± 0.4. The experimental data also agree within a factor of 0.8 ± 0.6 with the convolution of simulated proton fluence and cross sections from literature. Overall, this confirms the applicability of FLUKA to simulate radionuclide production at 13 MeV proton beam energy. Y1 - 2016 U6 - https://doi.org/10.1016/j.nimb.2015.10.067 SN - 1872-9584 VL - 366 SP - 117 EP - 123 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Bialonski, Stephan T1 - Are interaction clusters in epileptic networks predictive of seizures? T2 - Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics Y1 - 2016 SN - 978-143983886-0 SP - 349 EP - 355 PB - CRC Press ER - TY - JOUR A1 - Olbertz, Klaus T1 - Arbeitszeit und Vergütungspflicht des Arbeitgebers - Entstehung des Lohnanspruchs und arbeitsvertragliche Gestaltungsmöglichkeiten JF - NWB - Steuer- und Wirtschaftsrecht N2 - Kaum ein anderer Begriff hält so viele Varianten und Facetten bereit wie die Arbeitszeit. Für die betriebliche Praxis stellt sich dabei regelmäßig die Frage, was überhaupt zur Arbeitszeit gehört, entsprechend als solche zu vergüten ist und welche Optionen bei der Gestaltung der Arbeitsverträge bestehen. Der folgende Praxisleitfaden gibt einen Überblick über die aktuelle Rechtslage und enthält zugleich Hinweise für die Vertragsgestaltung. Die hierzu insbesondere in den letzten Jahren ergangenen zahlreichen aktuellen Gerichtsentscheidungen werden besonders berücksichtigt. Y1 - 2018 SN - 1860-9449 IS - 14 SP - 1026 EP - 1037 ER - TY - CHAP A1 - Schlösser, Karl Helmut T1 - Arbeitsvorbereitung und Ablaufplanung T2 - Zahlentafeln für den Baubetrieb N2 - Kosten- und Verfahrensvergleiche können dabei zur Ermittlung des für die Aufgabe geeignetsten Bauverfahren führen. Für die sich daran anschließende Ablaufplanung werden die verschiedenen graphischen sowie rechnerischen Instrumente (Terminliste und Taktplan, Balkenplan, Weg-Zeit-Diagramm und Netzplan) erläutert und anhand von Beispielen vertieft. Schließlich wird ein im Rahmen der Arbeits- und Nachkalkulation vorzunehmender Soll-Ist-Vergleich mit Hilfe des Bauarbeitsschlüssels (BAS) zur Überprüfung der Aufwands- und Leistungswerte dargestellt. Y1 - 2016 SN - 978-3-658-02838-1 (Online) SN - 978-3-658-02837-4 (Print) U6 - https://doi.org/10.1007/978-3-658-02838-1_8 SP - 1029 EP - 1067 PB - Springer Vieweg CY - Wiesbaden ET - 9., überarb. und aktual. Aufl. ER - TY - JOUR A1 - Olbertz, Klaus A1 - Groth, Alexandra T1 - Arbeitnehmerüberlassung: Neue gesetzliche Spielregeln ab dem 1.1.2017 JF - Gesellschafts- und Wirtschaftsrecht : GWR N2 - Die bereits mit Koalitionsvertrag vom 16.12.2013 in Aussicht genommene Neuregulierung der Leiharbeit steht nunmehr kurz bevor. Nach diversen Korrekturen des ursprünglichen Referentenentwurfes des Bundesministeriums für Arbeit und Soziales liegt seit dem 20.7.2016 der endgültige Entwurf des Gesetzes zur Änderung des Arbeitnehmerüberlassungsgesetzes und anderer Gesetze vor (AÜG-E). Die Änderungen sollen zum 1.1.2017 in Kraft treten. Von größeren Änderungen des Gesetzesentwurfs wird allgemein nicht mehr ausgegangen. Für die betriebliche Praxis sollte dies Anlass sein, sich bereits jetzt mit den sich abzeichnenden wichtigsten Neuerungen vertraut zu machen und diese entsprechend umzusetzen, um nachteilige Konsequenzen zu vermeiden. Y1 - 2018 SN - 1868-1816 SP - 371 EP - 374 ER - TY - JOUR A1 - Al-Kaidy, Huschyar A1 - Kuthan, Kai A1 - Hering, Thomas A1 - Tippkötter, Nils T1 - Aqueous droplets used as enzymatic microreactors and their electromagnetic actuation JF - Journal of Visualized Experiments N2 - For the successful implementation of microfluidic reaction systems, such as PCR and electrophoresis, the movement of small liquid volumes is essential. In conventional lab-on-a-chip-platforms, solvents and samples are passed through defined microfluidic channels with complex flow control installations. The droplet actuation platform presented here is a promising alternative. With it, it is possible to move a liquid drop (microreactor) on a planar surface of a reaction platform (lab-in-a-drop). The actuation of microreactors on the hydrophobic surface of the platform is based on the use of magnetic forces acting on the outer shell of the liquid drops which is made of a thin layer of superhydrophobic magnetite particles. The hydrophobic surface of the platform is needed to avoid any contact between the liquid core and the surface to allow a smooth movement of the microreactor. On the platform, one or more microreactors with volumes of 10 µL can be positioned and moved simultaneously. The platform itself consists of a 3 x 3 matrix of electrical double coils which accommodate either neodymium or iron cores. The magnetic field gradients are automatically controlled. By variation of the magnetic field gradients, the microreactors' magnetic hydrophobic shell can be manipulated automatically to move the microreactor or open the shell reversibly. Reactions of substrates and corresponding enzymes can be initiated by merging the microreactors or bringing them into contact with surface immobilized catalysts. Y1 - 2016 U6 - https://doi.org/10.3791/54643 SN - 1940-087X IS - Issue 126 ER - TY - CHAP A1 - Bung, Daniel Bernhard A1 - Valero, Daniel ED - Crookston, B. ED - Tullis, B. T1 - Application of the optical flow method to velocity determination in hydraulic structure models BT - Session 11: Fish passage and shiplocks T2 - Hydraulic Structures and Water System Management. 6th IAHR International Symposium on Hydraulic Structures, Portland, OR, 27-30 June 2016 Y1 - 2016 SN - 978-1-884575-75-4 U6 - https://doi.org/10.15142/T3150628160853 SP - 223 EP - 232 ER - TY - GEN A1 - Hering, T. A1 - Ulber, Roland A1 - Tippkötter, Nils T1 - Antimikrobielle Oberflächenmodifikation durch Mikropartikel T2 - Chemie Ingenieur Technik N2 - Die Ausbildung von Biofilmen in technischen Anlagen, wie z. B. Kühlkreisläufen, Wasseraufbereitungssystemen und Bioreaktoren, führen zu Materialschäden (Biofouling) und stark erhöhtem Energieaufwand. Im Rahmen der aktuellen Forschungsarbeiten erfolgen aktive sowie passive Bio-Modifikationen auf funktionalisierten magnetischen Mikropartikelober-flächen. Um die verschiedenen funktionalisierten magnetischen Mikropartikel zu analysieren und ihre antimikrobielle Wirkung zu testen, wird der Einsatz einer 3D-gedruckten, magnetischen Plattform für ein Fluoreszenz-basiertes Screening-System untersucht. Für den Oberflächenschutz wurden verschiedene, antimikrobiell funktionalisierte Partikelkombinationen mit dem Mikroorganismus Escherichia coli GFPmut2 in Bezug auf aktiven Oberflächenschutz verglichen. Um die antimikrobielle Oberflächeneffekte von synergistischen Kombinationen unterschiedlich funktionalisierter Partikel zu bestimmen, werden Oberflächen einem Magnetfeld ausgesetzt, das die Mikropartikel als definierte Schicht auf ihnen zurück hält. Diese modifizierten Oberflächen können sowohl durch Fluoreszenzspektroskopie als auch -mikroskopie analysiert werden. Y1 - 2016 U6 - https://doi.org/10.1002/cite.201650084 N1 - ProcessNet-Jahrestagung 2016 und 32. DECHEMA-Jahrestagung der Biotechnologen 2016, 12. - 15. September 2016, Eurogress Aachen VL - 88 IS - 9 SP - 1302 PB - Wiley-VCH CY - Weinheim ER - TY - GEN A1 - Olbertz, Klaus T1 - Annahmeverzugslohn bei Rückkehrrecht des Arbeitnehmers T2 - Gesellschafts- und Wirtschaftsrecht : GWR Y1 - 2018 SN - 1868-1816 N1 - Anmerkung zum BAG, Urteil vom 27.1.2016 – 5 AZR 9/15 (LAG Sachsen) SP - 408 EP - 408 ER - TY - JOUR A1 - Kroll-Ludwigs, Kathrin T1 - Anmerkung zu EuGH, Urt. v. 9.9.2015, Rs. C-4/14 Christophe Bohez v. Ingrid Wiertz JF - GRP : Zeitschrift für das Privatrecht der Europäischen Union N2 - Die Entscheidung in der Rechtssache Bohez /Wiertz bot dem EuGH Gelegenheit, zur Abgrenzung der Anwendungsbereiche von Brüssel I-(jetzt: Brüssel Ia-) und Brüssel IIa-VO Stellung zu nehmen. Den Ausgangspunkt bildete dabei ein familienrechtlicher Sachverhalt, nämlich die zwangsweise Durchsetzung des Umgangsrechts eines Vaters im Hinblick auf seine beiden Kinder. Auf den ersten Blick lag daher eine Anwendung der auf Verfahren betreffend die elterliche Verantwortung bezogenen Brüssel IIa-VO nahe. Andererseits schien auch eine Argumentation denkbar, wonach es sich bei dem zu vollstreckenden Anspruch auf Zahlung des Zwangsgeldes um eine Geldforderung handele, deren Vollstreckung nach der Brüssel I-VO zu erfolgen habe. Was vordergründig die Ermittlung des einschlägigen EU-Rechtsaktes betraf, erwies sich bei genauerer Betrachtung als Bestimmung der dogmatischen Rechtsnatur des Zwangsgeldes. Y1 - 2016 U6 - https://doi.org/10.9785/gpr-2016-0509 SN - 2193-9519 IS - 5 SP - 255 EP - 258 PB - Verlag Dr. Otto Schmidt CY - Köln ER - TY - GEN A1 - Olbertz, Klaus T1 - Angemessenheit eines Nachtarbeitszuschlags bei dauerhafter Nachtarbeit T2 - Gesellschafts- und Wirtschaftsrecht : GWR Y1 - 2018 SN - 1868-1816 N1 - Anm. zu BAG: Entscheidungsbesprechung zum Urteil v. 09.12.2015 - 10 AZR 423/14 SP - 151 EP - 151 ER - TY - JOUR A1 - Levers, A. A1 - Staat, Manfred A1 - Laack, Walter van T1 - Analysis of the long-term effect of the MBST® nuclear magnetic resonance therapy on gonarthrosis JF - Orthopedic Practice Y1 - 2016 VL - 47 IS - 11 SP - 521 EP - 528 ER - TY - CHAP A1 - Wulfhorst, H. A1 - Duwe, A. A1 - Möhring, S. A1 - Jurca, O. A1 - Tippkötter, Nils T1 - Analysis of pretreated biomass by differential scanning 132 calorimetry and multivariate data analysis T2 - New frontiers of biotech-processes (Himmelfahrtstagung) : 02-04 May 2016, Rhein-Mosel-Halle, Koblenz/Germany Y1 - 2016 SP - 132 PB - DECHEMA CY - Frankfurt am Main ER - TY - JOUR A1 - Ghosch, S. A1 - Baier, M. A1 - Schütz, J. A1 - Schneider, Felix A1 - Scherer, Ulrich W. T1 - Analysis of electronic autoradiographs by mathematical post-processing JF - Radiation Effects and Defects in Solids: Incorporating plasma science and plasma technology N2 - Autoradiography is a well-established method of nuclear imaging. When different radionuclides are present simultaneously, additional processing is needed to distinguish distributions of radionuclides. In this work, a method is presented where aluminium absorbers of different thickness are used to produce images with different cut-off energies. By subtracting images pixel-by-pixel one can generate images representing certain ranges of β-particle energies. The method is applied to the measurement of irradiated reactor graphite samples containing several radionuclides to determine the spatial distribution of these radionuclides within pre-defined energy windows. The process was repeated under fixed parameters after thermal treatment of the samples. The greyscale images of the distribution after treatment were subtracted from the corresponding pre-treatment images. Significant changes in the intensity and distribution of radionuclides could be observed in some samples. Due to the thermal treatment parameters the most significant differences were observed in the ³H and ¹⁴C inventory and distribution. Y1 - 2016 U6 - https://doi.org/10.1080/10420150.2016.1155587 SN - 1029-4953 VL - 171 IS - 1-2 SP - 161 EP - 172 PB - Taylor & Francis CY - London ER - TY - CHAP A1 - Heuermann, Holger A1 - Sadeghfam, Arash T1 - Analog Amplitude-Locked Loop Circuit to Support RF Energy Solutions T2 - IEEE MTT-S International Microwave Symposium Digest Y1 - 2016 SN - 978-150900698-4 U6 - https://doi.org/10.1109/MWSYM.2016.7540092 ER - TY - JOUR A1 - Niedermeyer, Angela A1 - Zhou, Bei A1 - Dursun, Gözde A1 - Temiz Artmann, Aysegül A1 - Markert, Bernd T1 - An examination of tissue engineered scaffolds in a bioreactor JF - Proceedings in Applied Mathematics and Mechanics PAMM N2 - Replacement tissues, designed to fill in articular cartilage defects, should exhibit the same properties as the native material. The aim of this study is to foster the understanding of, firstly, the mechanical behavior of the material itself and, secondly, the influence of cultivation parameters on cell seeded implants as well as on cell migration into acellular implants. In this study, acellular cartilage replacement material is theoretically, numerically and experimentally investigated regarding its viscoelastic properties, where a phenomenological model for practical applications is developed. Furthermore, remodeling and cell migration are investigated. Y1 - 2016 U6 - https://doi.org/10.1002/pamm.201610038 SN - 1617-7061 N1 - Joint Annual Meeting of DMV and GAMM 2016, 87th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM) and Deutsche Mathematiker-Vereinigung (DMV), Braunschweig, DE, Mar 7-11, 2016 VL - 16 IS - 1 SP - 99 EP - 100 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Harzheim, Thomas A1 - Heuermann, Holger A1 - Marso, Michel T1 - An Adaptive Biasing Method for SRD Comb Generators T2 - 2016 German Microwave Conference (GeMiC) Y1 - 2016 U6 - https://doi.org/10.1109/GEMIC.2016.7461613 N1 - GeMiC 2016 ; March 14–16, 2016, Bochum, Germany SP - 289 EP - 292 PB - IEEE ER - TY - BOOK A1 - Altherr, Lena T1 - Algorithmic System Design under Consideration of Dynamic Processes N2 - Nach Stand von Wissenschaft und Technik werden Komponenten hinsichtlich ihrer Eigenschaften, wie Lebensdauer oder Energieeffizienz, optimiert. Allerdings können selbst hervorragende Komponenten zu ineffizienten oder instabilen Systemen führen, wenn ihr Zusammenspiel nur unzureichend berücksichtigt wird. Eine Systembetrachtung schafft ein größeres Optimierungspotential - dem erhöhten Potential steht jedoch auch ein erhöhter Komplexitätsgrad gegenüber. Die vorliegende Arbeit ist im Rahmen des Sonderforschungsbereichs 805 entstanden, dessen Ziel die Beherrschung von Unsicherheit in Systemen des Maschinenbaus ist. Die Arbeit zeigt anhand eines realen Systems aus dem Bereich der Hydraulik, wie Unsicherheit in der Entwicklungsphase beherrscht werden kann. Hierbei ist neu, dass die durch den späteren Betrieb zu erwartende Systemdegradation eines jeden möglichen Systemvorschlags antizipiert werden kann. Dadurch können Betriebs- und Wartungskosten vorausgesagt und minimiert werden und durch eine optimale Betriebs- und Wartungsstrategie die Verfügbarkeit des Systems garantiert werden. Wesentliche Fragen bei der optimalen Auslegung des betrachteten hydrostatischen Getriebes sind dessen physikalische Modellierung, die Darstellung des Optimierungsproblems als gemischt-ganzzahliges lineares Programm, und dessen algorithmische Behandlung zur Lösungsfindung. Hierzu werden Heuristiken zum schnelleren Auffinden sinnvoller Systemtopologien vorgestellt und mittels mathematischer Dekomposition eine Bewertung des dynamischen Verschleiß- und Wartungsverlaufs möglicher Systemvorschläge vorgenommen. Die Arbeit stellt die Optimierung technischer Systeme an der Schnittstelle von Mathematik, Informatik und Ingenieurwesen sowohl gründlich als auch anschaulich und nachvollziehbar dar. KW - Mixed Integer Programming KW - Technical Operations Research KW - Optimization KW - System Design Y1 - 2016 SN - 978-3-8440-4848-3 PB - Shaker CY - Aachen ER - TY - JOUR A1 - Rösch, C. A1 - Kratz, F. A1 - Hering, T. A1 - Trautmann, S. A1 - Umanskaya, N. A1 - Tippkötter, Nils A1 - Müller-Renno, C.M. A1 - Ulber, Roland A1 - Hannig, M. A1 - Ziegler, C. T1 - Albumin-lysozyme interactions: cooperative adsorption on titanium and enzymatic activity JF - Colloids and Surfaces B: Biointerfaces N2 - The interplay of albumin (BSA) and lysozyme (LYZ) adsorbed simultaneously on titanium was analyzed by gel electrophoresis and BCA assay. It was found that BSA and lysozyme adsorb cooperatively. Additionally, the isoelectric point of the respective protein influences the adsorption. Also, the enzymatic activity of lysozyme and amylase (AMY) in mixtures with BSA was considered with respect to a possible influence of protein-protein interaction on enzyme activity. Indeed, an increase of lysozyme activity in the presence of BSA could be observed. In contrast, BSA does not influence the activity of amylase. Y1 - 2016 U6 - https://doi.org/10.1016/j.colsurfb.2016.09.048 VL - 149 IS - 1 SP - 115 EP - 121 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Otten, D. A1 - Schmidt, M. A1 - Weber, Tobias T1 - Advances in Determination of Material Parameters for Functional Simulations Based on Process Simulations T2 - SAMPE Europe Conference 16 Liege Y1 - 2016 SN - 978-1-5108-3800-0 SP - 570 EP - 577 ER - TY - BOOK A1 - Gebhardt, Andreas A1 - Hötter, Jan-Steffen T1 - Additive manufacturing : 3D printing for prototyping and manufacturing Y1 - 2016 SN - 978-1-56990-582-1 ; 978-1-56990-583-8 PB - Hanser Publishers CY - Munich ER - TY - BOOK A1 - Gebhardt, Andreas T1 - Additive Fertigungsverfahren : Additive Manufacturing und 3D-Drucken für Prototyping - Tooling - Produktion Y1 - 2016 SN - 978-3-446-44401-0 ; 978-3-446-44539-0 U6 - https://doi.org/10.3139/9783446445390 N1 - Verfügbar in der Bereichsbibliothek Eupener Straße unter 21 ZHU 25(5); verfügbar in der Bereichsbibliothek Jülich unter 61 ZHU 26(5) PB - Hanser CY - München ET - 5. aktualisierte und erweiterte Auflage ER - TY - GEN A1 - Olbertz, Klaus T1 - Abfindungsprogramm nach „Windhundprinzip“ ist zulässig T2 - Gesellschafts- und Wirtschaftsrecht : GWR Y1 - 2018 SN - 1868-1816 N1 - Anm. zu LAG Düsseldorf: Entscheidungsbesprechung zum Urteil v. 12.04.2016 - 14 Sa 1344/15 SP - 303 EP - 303 ER - TY - CHAP A1 - Neumann, Tobias A1 - Dülberg, Enno A1 - Schiffer, Stefan A1 - Ferrein, Alexander T1 - A rotating platform for swift acquisition of dense 3D point clouds T2 - Intelligent Robotics and Applications: 9th International Conference, ICIRA 2016, Tokyo, Japan, August 22-24, 2016, Proceedings, Part I Y1 - 2016 SN - 978-3-319-43505-3 (Print) SN - 978-3-319-43506-0 (Online) U6 - https://doi.org/10.1007/978-3-319-43506-0_22 N1 - Series: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) VL - 9834 SP - 257 EP - 268 PB - Springer ER - TY - JOUR A1 - Scheidweiler, Robert A1 - Triesch, Eberhard T1 - A note on the duality between matchings and vertex covers in balanced hypergraphs JF - Journal of Combinatorial Optimization N2 - We present a new Min-Max theorem for an optimization problem closely connected to matchings and vertex covers in balanced hypergraphs. The result generalizes Kőnig’s Theorem (Berge and Las Vergnas in Ann N Y Acad Sci 175:32–40, 1970; Fulkerson et al. in Math Progr Study 1:120–132, 1974) and Hall’s Theorem (Conforti et al. in Combinatorica 16:325–329, 1996) for balanced hypergraphs. KW - Hall’s Theorem KW - Koenig’s Theorem KW - Duality KW - Balanced hypergraph KW - Hypergraph KW - Vertex cover KW - Matching Y1 - 2016 U6 - https://doi.org/10.1007/s10878-015-9887-5 SN - 1573-2886 N1 - Lehrstuhl II für Mathematik RWTH Aachen VL - 32 IS - 2 SP - 639 EP - 644 PB - Springer CY - Berlin ER - TY - CHAP A1 - König, Johannes Alexander A1 - Wolf, Martin T1 - A new definition of competence developing games - and a framework to assess them T2 - ACHI 2016 : The Ninth International Conference on Advances in Computer-Human Interactions N2 - There are different types of games that try to make use of the motivation of a gaming situation in learning contexts. This paper introduces the new terminology ‘Competence Developing Game’ (CDG) as an umbrella term for all games with this intention. Based on this new terminology, an assessment framework has been developed and validated in scope of an empirical study. Now, all different types of CDGs can be evaluated according to a defined and uniform set of assessment criteria and, thus, are comparable according to their characteristics and effectiveness. KW - Serious Games KW - Gamification KW - Business Simulations KW - Assessment Y1 - 2016 SN - 978-1-61208-468-8 N1 - Proceeding of the Ninth International Conference on Advances in Computer-Human Interactions (ACHI 2016), Venice. SP - 95 EP - 97 ER - TY - CHAP A1 - Bäcker, Matthias A1 - Koch, C. A1 - Geiger, F. A1 - Eber, F. A1 - Gliemann, H. A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - A New Class of Biosensors Based on Tobacco Mosaic Virus and Coat Proteins as Enzyme Nanocarrier T2 - Procedia Engineering Y1 - 2016 U6 - https://doi.org/10.1016/j.proeng.2016.11.228 SN - 1877-7058 N1 - Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary VL - Vol. 168 SP - 618 EP - 621 ER - TY - JOUR A1 - Pookhalil, Ali A1 - Amoabediny, Ghassem A1 - Tabesh, Hadi A1 - Behbahani, Mehdi A1 - Mottaghy, Khosrow T1 - A new approach for semiempirical modeling of mechanical blood trauma JF - The international journal of artificial organs N2 - Purpose Two semi-empirical models were recently published, both making use of existing literature data, but each taking into account different physical phenomena that trigger hemolysis. In the first model, hemoglobin (Hb) release is described as a permeation procedure across the membrane, assuming a shear stress-dependent process (sublethal model). The second model only accounts for hemoglobin release that is caused by cell membrane breakdown, which occurs when red blood cells (RBC) undergo mechanically induced shearing for a period longer than the threshold time (nonuniform threshold model). In this paper, we introduce a model that considers the hemolysis generated by both these possible phenomena. Methods Since hemolysis can possibly be caused by permeation of hemoglobin through the RBC functional membrane as well as by release of hemoglobin from RBC membrane breakdown, our proposed model combines both these models. An experimental setup consisting of a Couette device was utilized for validation of our proposed model. Results A comparison is presented between the damage index (DI) predicted by the proposed model vs. the sublethal model vs. the nonthreshold model and experimental datasets. This comparison covers a wide range of shear stress for both human and porcine blood. An appropriate agreement between the measured DI and the DI predicted by the present model was obtained. Conclusions The semiempirical hemolysis model introduced in this paper aims for significantly enhanced conformity with experimental data. Two phenomenological outcomes become possible with the proposed approach: an estimation of the average time after which cell membrane breakdown occurs under the applied conditions, and a prediction of the ratio between the phenomena involved in hemolysis. Y1 - 2016 U6 - https://doi.org/10.5301/ijao.5000474 SN - 1724-6040 VL - 39 IS - 4 SP - 171 EP - 177 PB - Sage CY - London ER - TY - JOUR A1 - Orzada, Stephan A1 - Ladd, Mark E. A1 - Bitz, Andreas T1 - A method to approximate maximum local SAR in multichannel transmit MR systems without transmit phase information JF - Magnetic Resonance in Medicine N2 - Purpose To calculate local specific absorption rate (SAR) correctly, both the amplitude and phase of the signal in each transmit channel have to be known. In this work, we propose a method to derive a conservative upper bound for the local SAR, with a reasonable safety margin without knowledge of the transmit phases of the channels. Methods The proposed method uses virtual observation points (VOPs). Correction factors are calculated for each set of VOPs that prevent underestimation of local SAR when the VOPs are applied with the correct amplitudes but fixed phases. Results The proposed method proved to be superior to the worst-case calculation based on the maximum eigenvalue of the VOPs. The mean overestimation for six coil setups could be reduced, whereas no underestimation of the maximum local SAR occurred. In the best investigated case, the overestimation could be reduced from a factor of 3.3 to a factor of 1.7. Conclusion The upper bound for the local SAR calculated with the proposed method allows a fast estimation of the local SAR based on power measurements in the transmit channels and facilitates SAR monitoring in systems that do not have the capability to monitor transmit phases Y1 - 2016 U6 - https://doi.org/10.1002/mrm.26398 SN - 1522-2594 VL - 78 IS - 2 SP - 805 EP - 811 PB - International Society for Magnetic Resonance in Medicine ER - TY - JOUR A1 - Koster, Arie A1 - Scheidweiler, Robert A1 - Tieves, Martin T1 - A flow based pruning scheme for enumerative equitable coloring algorithms JF - A flow based pruning scheme for enumerative equitable coloring algorithms N2 - An equitable graph coloring is a proper vertex coloring of a graph G where the sizes of the color classes differ by at most one. The equitable chromatic number is the smallest number k such that G admits such equitable k-coloring. We focus on enumerative algorithms for the computation of the equitable coloring number and propose a general scheme to derive pruning rules for them: We show how the extendability of a partial coloring into an equitable coloring can be modeled via network flows. Thus, we obtain pruning rules which can be checked via flow algorithms. Computational experiments show that the search tree of enumerative algorithms can be significantly reduced in size by these rules and, in most instances, such naive approach even yields a faster algorithm. Moreover, the stability, i.e., the number of solved instances within a given time limit, is greatly improved. Since the execution of flow algorithms at each node of a search tree is time consuming, we derive arithmetic pruning rules (generalized Hall-conditions) from the network model. Adding these rules to an enumerative algorithm yields an even larger runtime improvement. Y1 - 2016 U6 - https://doi.org/10.48550/arXiv.1607.08754 N1 - Lehrstuhl II für Mathematik, RWTH Aachen University SP - 1 EP - 30 ER - TY - JOUR A1 - Weber, Tobias A1 - Arent, Jan-Christoph A1 - Münch, Lukas A1 - Duhovic, Miro A1 - Balvers, Johannes M. T1 - A fast method for the generation of boundary conditions for thermal autoclave simulation JF - Composites Part A N2 - Manufacturing process simulation enables the evaluation and improvement of autoclave mold concepts early in the design phase. To achieve a high part quality at low cycle times, the thermal behavior of the autoclave mold can be investigated by means of simulations. Most challenging for such a simulation is the generation of necessary boundary conditions. Heat-up and temperature distribution in an autoclave mold are governed by flow phenomena, tooling material and shape, position within the autoclave, and the chosen autoclave cycle. This paper identifies and summarizes the most important factors influencing mold heat-up and how they can be introduced into a thermal simulation. Thermal measurements are used to quantify the impact of the various parameters. Finally, the gained knowledge is applied to develop a semi-empirical approach for boundary condition estimation that enables a simple and fast thermal simulation of the autoclave curing process with reasonably high accuracy for tooling optimization. Y1 - 2016 U6 - https://doi.org/10.1016/j.compositesa.2016.05.036 SN - 1359-835X VL - 88 SP - 216 EP - 225 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Rausch, Lea A1 - Leise, Philipp A1 - Ederer, Thorsten A1 - Altherr, Lena A1 - Pelz, Peter F. ED - Papadrakakis, M. ED - Ppadopoulos, V. ED - Stefanou, G. ED - Plevris, V. T1 - A comparison of MILP and MINLP solver performance on the example of a drinking water supply system design problem T2 - ECCOMAS Congress 2016 VII European Congress on Computational Methods in Applied Sciences and Engineering N2 - Finding a good system topology with more than a handful of components is a highly non-trivial task. The system needs to be able to fulfil all expected load cases, but at the same time the components should interact in an energy-efficient way. An example for a system design problem is the layout of the drinking water supply of a residential building. It may be reasonable to choose a design of spatially distributed pumps which are connected by pipes in at least two dimensions. This leads to a large variety of possible system topologies. To solve such problems in a reasonable time frame, the nonlinear technical characteristics must be modelled as simple as possible, while still achieving a sufficiently good representation of reality. The aim of this paper is to compare the speed and reliability of a selection of leading mathematical programming solvers on a set of varying model formulations. This gives us empirical evidence on what combinations of model formulations and solver packages are the means of choice with the current state of the art. KW - Technical Operations Research KW - Mixed-Integer Nonlinear Optimisation KW - Solver Per- formance KW - Drinking Water Supply KW - System Design Problem Y1 - 2016 SN - 978-618-82844-0-1 N1 - ECCOMAS Congress 2016 VII European Congress on Computational Methods in Applied Sciences and Engineering, 5–10 June 2016.Crete Island, Greece SP - 8509 EP - 8527 ER - TY - JOUR A1 - Scheer, Nico A1 - Wilson, Ian D. T1 - A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity JF - Drug Discovery Today N2 - Mice that have been genetically humanized for proteins involved in drug metabolism and toxicity and mice engrafted with human hepatocytes are emerging and promising in vivo models for an improved prediction of the pharmacokinetic, drug–drug interaction and safety characteristics of compounds in humans. The specific advantages and disadvantages of these models should be carefully considered when using them for studies in drug discovery and development. Here, an overview on the corresponding genetically humanized and chimeric liver humanized mouse models described to date is provided and illustrated with examples of their utility in drug metabolism and toxicity studies. We compare the strength and weaknesses of the two different approaches, give guidance for the selection of the appropriate model for various applications and discuss future trends and perspectives. Y1 - 2016 U6 - https://doi.org/10.1016/j.drudis.2015.09.002 SN - 1359-6446 VL - 21 IS - 2 SP - 250 EP - 263 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Duong, Minh Tuan A1 - Jung, Alexander A1 - Frotscher, Ralf A1 - Staat, Manfred ED - Papadrakakis, M. T1 - A 3D electromechanical FEM-based model for cardiac tissue T2 - ECCOMAS Congress 2016, VII European Congress on Computational Methods in Applied Sciences and Engineering. Crete Island, Greece, 5–10 June 2016 Y1 - 2016 N1 - revised after the conference P11367 ER - TY - BOOK A1 - Gebhardt, Andreas A1 - Kessler, Julia A1 - Thurn, Laura T1 - 3D-Drucken: Grundlagen und Anwendungen des additive manufacturing (AM) Y1 - 2016 SN - 978-3-446-44672-4 U6 - https://doi.org/10.3139/9783446448452 PB - Hanser CY - München ET - 2., neu bearbeitete und erweiterte Auflage ER - TY - JOUR A1 - Ferrein, Alexander A1 - Steinbauer, Gerald T1 - 20 Years of RoboCup - A Subjective Retrospection JF - KI - Künstliche Intelligenz N2 - This summer, RoboCup competitions were held for the 20th time in Leipzig, Germany. It was the second time that RoboCup took place in Germany, 10 years after the 2006 RoboCup in Bremen. In this article, we give an overview on the latest developments of RoboCup and what happened in the different leagues over the last decade. With its 20th edition, RoboCup clearly is a success story and a role model for robotics competitions. From our personal view point, we acknowledge this by giving a retrospection about what makes RoboCup such a success. Y1 - 2016 U6 - https://doi.org/10.1007/s13218-016-0449-5 SN - 1610-1987 VL - 30 IS - 3 SP - 225 EP - 232 PB - Springer CY - Berlin ER - TY - JOUR A1 - Steinbauer, Gerald A1 - Ferrein, Alexander T1 - 20 Years of RoboCup JF - KI - Künstliche Intelligenz Y1 - 2016 U6 - https://doi.org/10.1007/s13218-016-0442-z SN - 1610-1987 VL - 30 IS - 3-4 SP - 221 EP - 224 PB - Springer CY - Berlin ER - TY - CHAP A1 - Fissabre, Anke A1 - Wilson, Ariane ED - Feiglstorfer, Hubert T1 - "Lehmbaupropaganda" : On the tradition of earth building literature T2 - Earth Construction and Tradition. Vol. I Y1 - 2016 SN - 978-3-900265-34-2 SP - 47 EP - 69 PB - IVA Institut für vergleichende Architekturforschung CY - Wien ER -