TY - JOUR A1 - Biselli, Manfred A1 - Thömmes, J. A1 - Born, C. A1 - Wandrey, C. T1 - Purification of monoclonal antibodies by fluidized bed adsorption / Thömmes, J. ; Born, C. Biselli, M. ; Wandrey, C. ; Kula, M.-R. JF - Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery Y1 - 1995 SN - 0-7923-3736-0 N1 - Meeting "Animal Cell Technology, Developments towards the 21st Century" ; <1994.09.12-16 : ; Veldhoven> SP - 515 EP - 519 PB - Kluwer Acad. Press CY - Dordrecht ER - TY - JOUR A1 - Biselli, Manfred A1 - Born, C. A1 - Wandrey, C. T1 - Production of monoclonal antibodies in a pilot scale fluidized bed bioreactor / Born, C.; Biselli, M.; Wandrey, C. JF - Animal cell technology : developments towards the 21st century / edited by E. C. Beuvery Y1 - 1995 SN - 0-7923-3736-0 N1 - Meeting "Animal Cell Technology, Developments towards the 21st Century" ; <1994.09.12-16 : ; Veldhoven> SP - 515 EP - 519 PB - Kluwer Acad. Press CY - Dordrecht ER - TY - JOUR A1 - Biselli, Manfred A1 - Born, C. A1 - Thömmes, J. A1 - Wandrey, C. T1 - An approach to integrated antibody production: Coupling of fluidized bed cultivation and fluidized bed adsorption / Born, C. ; Thömmes, J. ; Biselli, M. ; Wandrey, C. ; Kula, M.-R. JF - Bioprocess Engineering. 15 (1996), H. 1 Y1 - 1996 SN - 1615-7591 SP - 21 EP - 29 ER - TY - JOUR A1 - Biselli, Manfred A1 - Noll, T. A1 - Wandrey, C. T1 - On-line biomass monitoring of immobilized hybridoma cells by dielectrical measurements / Noll, T. ; Biselli, M. ; Wandrey, C. JF - Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo Y1 - 1997 SN - 0-7923-4321-2 SP - 289 EP - 294 PB - Kluwer CY - Dordrecht ER - TY - JOUR A1 - Biselli, Manfred A1 - Schröder, B. A1 - Herfurth, C. A1 - Meißner, P. T1 - Differentiation of bone marrow cells immobilized on microcarriers in a fluidized bed reactor / Schröder, B. ; Herfurth, C. ; Meißner, P. ; Biselli, M. ; Link, H. ; Wandrey, C. JF - Animal cell technology : from vaccines to genetic medicine ; [Vilamoura, Portugal, May 1996] / ed. by Manuel J. T. Carrondo Y1 - 1997 SN - 0-7923-4321-2 SP - 589 EP - 593 PB - Kluwer CY - Dordrecht ER - TY - JOUR A1 - Biselli, Manfred A1 - Van der Pol, Jens J. A1 - De Gooijer, Cornelis D. A1 - Wandrey, Christian T1 - Automation of selective assays for on-line bioprocess monitoring by flow-injection analysis / van der Pol, Jens J. ; de Gooijer, Cornelis D. ; Biselli, Manfred ; Wandrey, Christian ; Tramper, Johannes JF - Trends in Biotechnology. 14 (1996), H. 12 Y1 - 1996 SN - 0167-7799 SP - 471 EP - 477 ER - TY - JOUR A1 - Baumann, Marcus A1 - Goeyens, L. A1 - Semeneh, M. A1 - Elskens, M. T1 - Phytoplankton nutrient utilisation and nutrient signature in the Southern Ocean / Goeyens, L. ; Semeneh, M. ; Baumann, M.E.M. ; Elskens, M. ; Shopova, D. ; Dehairs, F. JF - Journal of Marine Systems. 17 (1998), H. 1-4 Y1 - 1998 SN - 0924-7963 SP - 143 EP - 157 ER - TY - JOUR A1 - Baumann, Marcus A1 - Semeneh, M. A1 - Dehairs, F. A1 - Elskens, M. T1 - Nitrogen uptake regime and phytoplankton community structure in the Southern Ocean / Semeneh, M. ; Dehairs, F. ; Elskens, M. ; Baumann, M.E.M. ; Kopczynska, E.E. ; Lancelot, C. ; Goeyens, L. JF - Journal of Marine Systems. 17 (1998), H. 1-4 Y1 - 1998 SN - 0924-7963 SP - 159 EP - 177 ER - TY - BOOK A1 - Lauth, Jakob A1 - Dingerdissen, Uwe A1 - Steuerle, Ulrich T1 - Cup catalyst and process for producing aziridines : [Internationale Pantentanmeldung WO9633018] ; Veröffentlichungsdatum: 1996-10-24 / Anmelder: BASF AG ; Dingerdissen, Uwe ; Lauth, Guenther ; Steuerle, Ulrich. Erfinder: Dingerdissen, Uwe ; Lauth, Guenther ; Steuerle, Ulrich Y1 - 1996 PB - [Weltorganisation für geistiges Eigentum] CY - [Genf] ER - TY - PAT A1 - Lauth, Jakob T1 - Preparation of O-(2-hydroxyalkyl) oximes : patent application CA 2196452 ; filing date: 1995-07-28 ; national entry: 1997-01-30 / applicants: BASF Aktiengesellschaft. Inventors: Harreus, Albrecht ; Gotz, Norbert ; Rang, Harald ... Lauth, Guenther ... Y1 - 1995 N1 - International publication number: WO1996/004238 PB - Canadian International Property Office CY - [Gatineau, Quebec] ER - TY - PAT A1 - Lauth, Jakob A1 - Harreus, Albrecht A1 - Goetz, Norbert A1 - Rang, Harald T1 - Preparation of O-(2-hydroxyalkyl) oximes : [South African Patent ] publication number: ZA9506402 ; publication date: 1997-02-03 / applicant: BASF AG. Inventor: Harreus, Albrecht ; Goetz, Norbert ; Rang, Harald .... Lauth, Guenter ... Y1 - 1997 N1 - Also published as WO9604238 PB - [South African Companies and Intellectual Property Registration Office] CY - [Pretoria] ER - TY - PAT A1 - Lauth, Jakob A1 - Müller, Ulrich A1 - Hoelderich, Wolfgang T1 - Colored crystalline aluminophosphates and/or silicoaluminophosphates of the AEL or VFI type : United States Patent ; patent number 5,360,474 ; date of patent: Nov. 1, 1994 / assignee: BASF Aktiengesellschaft Y1 - 1994 N1 - Barcode: US005360474A ; Volltext über Datenbank: http://www.google.com/patents PB - [United States Trademark and Patent Office] CY - [Alexandria, VA] ER - TY - PAT A1 - Lauth, Jakob A1 - Wolf, Gerhard A1 - Burkhart, Bernd T1 - Preparation of alkoxylation products in the presence of mixed hydroxides modified with additives : United States Patent ; patent number 5,741,947 ; date of patent: Apr. 21, 1998 / assignee: BASF Aktiengesellschaft. Inventors: Gerhard Wolf ; Bernd Burkhart ; Guenter Lauth ... Y1 - 1998 N1 - Barcode: US005741947A ; Volltext über Datenbank: http://www.google.com/patents PB - [United States Trademark and Patent Office] CY - [Alexandria, VA] ER - TY - PAT A1 - Lauth, Jakob A1 - Hoelderich, Wolfgang A1 - Wagenblast, Gerhard T1 - Molecular sieves containing azo dyes : United States Patent ; patent number 5,573,585 ; date of patent: Nov. 12, 1996 / assignee: Wolfgang Hoelderich. Inventors: Guenter Lauth ; Wolfgang Hoelderich ; Gerhard Wagenblast ... Y1 - 1996 N1 - Barcode: US005573585A ; Volltext über Datenbank: http://www.google.com/patents PB - [United States Trademark and Patent Office] CY - [Alexandria, VA] ER - TY - PAT A1 - Lauth, Jakob A1 - Dingerdissen, Uwe A1 - Henne, Andreas T1 - Preparation of amines : United States Patent ; patent number 5,817,871 ; date of patent: Oct. 6, 1998 / Assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Andreas Henne .... Y1 - 1998 N1 - Barcode: US005817871A ; Volltext über Datenbank: http://www.google.com/patents ; Falsche Namensansetzung: Gunter ... PB - [United States Trademark and Patent Office] CY - [Alexandria, VA] ER - TY - PAT A1 - Lauth, Jakob A1 - Dingerdissen, Uwe A1 - Trübenbach, Peter A1 - Steuerle, Ulrich T1 - Preparation of aziridines : United States Patent ; patent number 5,693,825 ; date of patent: Dec. 2, 1997 / assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Peter Trubenbach ; Ulrich Steuerle Y1 - 1997 N1 - Barcode: US005324493A ; Volltext über Datenbank: http://www.google.com/patents ; Falsche Namensansetzung in Datenbank: Gunter ... PB - United States Patent and Trademark Office CY - [Alexandria, VA] ER - TY - PAT A1 - Lauth, Jakob A1 - Trübenbach, Peter A1 - Hagemeyer, Alfred T1 - Monomodal and polymodal catalyst supports and catalysts having narrow pore size distributions and their production : United States Patent ; patent number 5,935,898 ; date of patent: Aug. 10, 1999 / assignee: BASF Aktiengesellschaft. Inventors: Peter Trubenbach ; Alfred Hagemeyer ; Gunter Lauth ... Y1 - 1999 N1 - Barcode: US005935898A ; Volltext über Datenbank: http://www.google.com/patents ; Falsche Namensansetzung in Datenbank: Gunter ... PB - [United States Patent and Trademark Office] CY - [Alexandria, VA] ER - TY - JOUR A1 - Baumann, Marcus A1 - Tillmann, U. A1 - Aletsee, L. T1 - Distribution of Carbon Among Photosynthetic End Products in the Bloom-Forming Arctic Diatom Thalassiosira antarctica COMBER / Tillmann, U. ; Baumann, M.E.M. ; Aletsee, L. JF - Polar Biology. 10 (1989), H. 3 Y1 - 1989 SN - 0722-4060 SP - 231 EP - 238 ER - TY - JOUR A1 - Baumann, Marcus A1 - Gradinger, R. T1 - Distribution of Phytoplankton Communities in Relation to the Large Scale Hydrographical Regime in the Fram Strait 1984 / Gradinger, R. ; Baumann, M.E.M. JF - Marine Biology. 111 (1991), H. 2 Y1 - 1991 SN - 0025-3162 SP - 311 EP - 321 ER - TY - JOUR A1 - Baumann, Marcus A1 - Hirche, H.-J. A1 - Kattner, G. A1 - Gradinger, R. T1 - Plankton distribution and the impact of copepod grazing on primary production in Fram Strait, Greenland Sea / Hirche, H.-J. ; Baumann, M.E.M. ; Kattner, G.; Gradinger, R. JF - Journal of Marine Systems. 2 (1991), H. 3-4 Y1 - 1991 SN - 0924-7963 SP - 477 EP - 494 ER - TY - JOUR A1 - Baumann, Marcus A1 - Thomas, D. A1 - Gleitz, M. T1 - Efficiency of carbon assimilation and photoacclimation in a small unicellular Chaetoceros species from the Weddel Sea (Antarctica): Influence of temperature and irridiance / Thomas, D. ; Baumann, M.E.M. ; Gleitz, M. JF - Journal of Experimental Marine Biology and Ecology. 157 (1992), H. 2 Y1 - 1992 SN - 0022-0981 SP - 195 EP - 209 ER - TY - JOUR A1 - Baumann, Marcus A1 - Brandini, Frederico A1 - Staubes, Regina T1 - The influence of light and temperature on carbonspecific DMS release by cultures of Phaeocystis antarctica and three antarctic diatoms / Baumann, Marcus E.M. ; Brandini, Frederico ; Staubes, Regina JF - Marine Chemistry. 45 (1994), H. 1-2 Y1 - 1994 SN - 0304-4203 SP - 129 EP - 136 ER - TY - JOUR A1 - Baumann, Marcus A1 - Lancelot, C. A1 - Brandini, F. A1 - Sakshaug, E. T1 - The taxonomic identity of the cosmopolitan prymnesiophyte Phaeocystis, a morphological and ecophysiological approach / Baumann, M.E.M. ; Lancelot, C. ; Brandini, F. ; Sakshaug, E. ; John M. JF - Journal of Marine Systems. 5 (1994), H. 1 Y1 - 1994 SN - 0924-7963 SP - 5 EP - 22 ER - TY - JOUR A1 - Baumann, Marcus A1 - Rousseau, V. A1 - Vaulot, D. A1 - Casotti, R. T1 - The life cycle of Phaeocystis (Prymnesiophycae): evidence and hypotheses / Rousseau, V. ; Vaulot, D. ; Casotti, R. ; Cariou, V. ; Lenz, J. ; Gunkel, J. ; Baumann, M. JF - Journal of Marine Systems. 5 (1994), H. 1 Y1 - 1994 SN - 0924-7963 SP - 23 EP - 39 ER - TY - JOUR A1 - Baumann, Marcus A1 - Lara, R.J. A1 - Hubberten, D.N. A1 - Thomas, D.N. T1 - Dissolved organic matter studies in enclosed systems: Application of hydophobic fractionation for the assessment of organic nitrogen dynamics / Lara, R.J. ; Hubberten, U. ; Thomas, D.N. ; Baumann, M.E.M. ; Kattner, G. JF - Journal of Marine Systems. 13 (1997), H. 1-4 Y1 - 1997 SN - 0924-7963 SP - 155 EP - 161 ER - TY - JOUR A1 - Baumann, Marcus A1 - Jahnke, J. T1 - Chemical and Physical Effects on the Shape and Growth of the Diatom Biddulphia sinensis GREVILLE in Batch Cultures: A Contribution to Bioindication in Plankton Ecology / Jahnke, J. ; Baumann, M. JF - Hydrobiological Bulletin . 17 (1983), H. 1 Y1 - 1983 SN - 0165-1404 SP - 5 EP - 20 ER - TY - PAT A1 - Lauth, Jakob A1 - Hoelderich, Wolfgang A1 - Harth, Klaus A1 - Hibst, Hartmuth T1 - Coated catalysts : United States Patent ; patent number 5,559,065 ; date of patent: Sep. 24, 1996 / assignee: BASF Aktiengesellschaft Y1 - 1996 N1 - Barcode: US005559065A ; Volltext über Datenbank: http://www.google.com/patents PB - [United States Trademark and Patent Office] CY - [Alexandria, VA] ER - TY - PAT A1 - Lauth, Jakob A1 - Müller, Ulrich A1 - Hoelderich, Wolfgang T1 - Preparation of aluminophosphates and silicoaluminophosphates having the AEL structure using 1,2-bis-( 4-pyridyl)-ethane : United States Patent ; patent number 5,324,493 ; date of patent: Jun. 28, 1994 / assignee: BASF Aktiengesellschaft. Inventors: Ulrich Mueller ; Wolfgang Hoelderich ; Guenter Lauth Y1 - 1994 N1 - Barcode: US005324493A ; Volltext über Datenbank: http://www.google.com/patents PB - [United States Trademark and Patent Office] CY - [Alexandria, VA] ER - TY - JOUR A1 - Wagner, Torsten A1 - Molina, R. A1 - Biselli, Manfred A1 - Canzoneri, Michele A1 - Schnitzler, Thomas A1 - Yoshinobu, Tatsuo A1 - Schöning, Michael Josef T1 - A light-addressable potentiometric sensor system for fast, simultaneous and spatial detection of the metabolic activity of biological cells JF - Transducers '07 Eurosensors XXI : digest of technical papers ; the14th International Conference on Solid-State Sensors, Actuators and Microsystems, June 10-14, 2007, Lyon, France / Gilles Delapierre (Ed.) Y1 - 2007 SN - 1-4244-0841-5 N1 - Eurosensors 21, 2007, Lyon ; International Conference on Solid-State Sensors, Actuators and Microsystems 14, 2007, Lyon SP - 1107 EP - 1110 PB - IEEE CY - Piscataway ER - TY - JOUR A1 - Selmer, Thorsten A1 - Jennemann, Richard A1 - Bauer, Bernhard L. A1 - Bertalanffy, Helmut T1 - Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus / Jennemann, Richard ; Bauer, Bernhard, L. ; Bertalanffy, Helmut ; Geyer, Rudolf ; Gschwind, Ruth, M. ; Selmer, Thorsten ; Wiegandt, Herbert JF - European Journal of Biochemistry. 259 (1999), H. 1-2 Y1 - 1999 SN - 0014-2956 SP - 331 EP - 338 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Hallmann, Armin A1 - Schmidt, Bernhard A1 - Sumper, Manfred T1 - The Evolutionary Conservation of a Novel Protein Modification, the Conversion of Cysteine to Serinesemialdehyde in Arylsulfatase from Volvox carteri / Selmer, Thorsten ; Hallmann, Armin ; Schmidt, Bernhard ; Sumper, Manfred ; Figura, Kurt von JF - European Journal of Biochemistry. 238 (1996), H. 2 Y1 - 1996 SN - 0014-2956 SP - 341 EP - 345 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Scott, Richard A1 - Näser, Ulrike A1 - Friedrich, Peter T1 - Stereochemistry of hydrogen removal from the 'unactivated' C-3 position of 4-hydroxybutyryl-CoA catalysed by 4-hydroxybutyryl-CoA dehydratase / Scott, R. ; Näser, U. ; Friedrich, P. ; Selmer, T. ; Buckel, W. ; Golding, BT. JF - Chemical Communications : ChemCom (2004) Y1 - 2004 SN - 1364-548X SP - 1210 EP - 1211 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Thamer, Wiebke A1 - Cirpus, Irina A1 - Hans, Marcus T1 - A two [4Fe-4S]-cluster-containing ferredoxin as an alternative electron donor for 2-hydroxyglutaryl-CoA dehydratase from Acidaminococcus fermentans / Thamer, Wiebke ; Cirpus, Irina ; Hans, Marcus ; Pierik, Antonio, J. ; Selmer, Thorsten ; Bill, Eckhard ; JF - Archives of Microbiology. 179 (2003), H. 3 Y1 - 2003 SN - 1432-072X SP - 197 EP - 204 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Netz, Daili Jacqueline Aguilar A1 - Pohl, Regula A1 - Beck-Sickinger, Annette G. T1 - Biochemical characterisation and genetic analysis of aureocin A53, a new, atypical bacteriocin from Staphylococcus aureus / Netz, Daili Jacqueline Aguilar ; Pohl, Regula ; Beck-Sickinger, Annette G. ; Selmer, Thorsten ; Pierik, Antonio J. ; Carmo de Frei JF - Journal of Molecular Biology. 319 (2002), H. 3 Y1 - 2002 SN - 0022-2836 SP - 745 EP - 756 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Schmidt, Bernhard A1 - Ingendoh, Arnd A1 - Figura, Kurt von T1 - A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency / Schmidt, Bernhard ; Selmer, Thorsten ; Ingendoh, Arnd ; Figurat, Kurt von JF - Cell. 82 (1995), H. 2 Y1 - 1995 SN - 0092-8674 SP - 271 EP - 278 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Kahnt, Jörg A1 - Goubeaud, Marcel A1 - Shima, Seigo T1 - The biosynthesis of methylated amino acids in the active site region of methyl-coenzyme M reductase / Selmer, Thorsten ; Kahnt, Jörg ; Goubeaud, Marcel ; Shima, Seigo ; Grabarse, Wolfgang ; Ermler, Ulrich ; Thauer, Rudolf K. JF - Journal of Biological Chemistry. 275 (2000), H. 6 Y1 - 2000 SN - 1083-351X SP - 3775 EP - 3760 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Brüser, Thomas A1 - Dahl, Christiane T1 - ADP Sulfurylase" from Thiobacillus denitrificans Is an Adenylylsulfate:Phosphate Adenylyltransferase and Belongs to a New Family of Nucleotidyltransferases / Brüser, Thomas ; Selmer, Thorsten ; Dahl, Christiane JF - Journal of Biological Chemistry. 275 (2000), H. 3 Y1 - 2000 SN - 1083-351X SP - 1691 EP - 1690 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Buckel, Wolfgang T1 - Oxygen Exchange between Acetate and the Catalytic Glutamate Residue in Glutaconate CoA-transferase from Acidaminococcus fermentans. IMPLICATIONS FOR THE MECHANISM OF CoA-ESTER HYDROLYSIS JF - Journal of Biological Chemistry. 274 (1999), H. 30 Y1 - 1999 SN - 1083-351X SP - 20772 EP - 20778 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Recksiek, Michael A1 - Dierks, Thomas A1 - Schmidt, Bernhard T1 - Sulfatases, Trapping of the Sulfated Enzyme Intermediate by Substituting the Active Site Formylglycine / Recksiek, Michael ; Selmer, Thorsten ; Dierks, Thomas ; Schmidt, Bernhard ; Figura, Kurt von JF - Journal of Biological Chemistry. 273 (1998), H. 11 Y1 - 1998 SN - 1083-351X SP - 6096 EP - 6103 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Miech, Claudia A1 - Dierks, Thomas A1 - Figura, Kurt von T1 - Arylsulfatase from Klebsiella pneumoniae Carries a Formylglycine Generated from a Serine / Miech, Claudia ; Dierks, Thomas ; Selmer, Thorsten ; Figura, Kurt von ; Schmidt, Bernd JF - Journal of Biological Chemistry. 273 (1998), H. 9 Y1 - 1998 SN - 1083-351X SP - 4835 EP - 4837 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Sommerlade, Hans-Jörg A1 - Ingendoh, Arnd A1 - Gieselmann, Volkmar T1 - Glycosylation and phosphorylation of arylsulfatase A / Sommerlade, Hans-Jörg. ; Selmer, Thomas. ; Ingendoh, Arnd ; Gieselmann, Volkmar ; Figura, Kurt von ; Neifer, Klaus ; Schmidt, Bernhard JF - Journal of Biological Chemistry. 269 (1994), H. 33 Y1 - 1994 SN - 1083-351X SP - 20977 EP - 20981 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Jennemann, Richard A1 - Bauer, Bernhard L. A1 - Bertalanffy, Helmut T1 - Basidiolipids from Agaricus are novel immune adjuvants / Jennemann, R. ; Bauer, BL. ; Bertalanffy, H. ; Selmer, T. ; Wiegandt, H. JF - Immunobiology. 200 (1999), H. 2 Y1 - 1999 SN - 0171-2985 N1 - PMID: 10416134 SP - 277 EP - 289 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Figura, Kurt von A1 - Schmidt, Bernhard A1 - Dierks, T. T1 - A novel protein modification generating an aldehyde group in sulfatases: its role in catalysis and disease / Figura, Kurt von ; Schmidt, Bernhard ; Selmer, Thorsten ; Dierks, Thomas JF - Bioessays. 20 (1998), H. 6 Y1 - 1998 SN - 1521-1878 SP - 505 EP - 510 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Lukatela, G. A1 - Krauss, N. A1 - Theis, K. T1 - Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis / Lukatela, G. ; Krauss, N. ; Theis, K. ; Selmer, T. ; Gieselmann, V. ; Figura, K. von ; Saenger, JF - Biochemistry. 37 (1998), H. 11 Y1 - 1998 SP - 3654 EP - 3664 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Kim, Jihoe A1 - Darley, Daniel A1 - Buckel, Wolfgang T1 - Characterization of (R)-2-hydroxyisocaproate dehydrogenase and a family III coenzyme A transferase involved in reduction of L-leucine to isocaproate by Clostridium difficile / Kim, J. ; Darley, D. ; Selmer, T. ; Buckel, W. JF - Applied and Environmental Microbiology. 72 (2006), H. 9 Y1 - 2006 SN - 0099-2240 N1 - PMID: 16957230 SP - 6062 EP - 6069 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Yu, Lihua A1 - Blaser, Martin A1 - Andrei, Paula I. T1 - 4-Hydroxyphenylacetate decarboxylases: properties of a novel subclass of glycyl radical enzyme systems / Yu, L. ; Blaser, M. ; Andrei, PI. ; Pierik, AJ. Selmer, T. JF - Biochemistry. 31 (2006), H. 45 Y1 - 2006 N1 - PMID: 16878993 SP - 9584 EP - 9592 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Pierik, Antonio J. A1 - Heider, Johann T1 - New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria JF - Biological Chemistry. 386 (2005), H. 10 Y1 - 2005 SN - 1431-6730 SP - 981 EP - 988 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Achebach, Stephanie A1 - Unden, Gottfried T1 - Properties and significance of apoFNR as a second form of air-inactivated [4Fe-4S]·FNR of Escherichia coli / Achebach, S. ; Selmer, T. ; Unden, G. JF - The FEBS Journal. 272 (2005), H. 16 Y1 - 2005 SN - 1742-464X SP - 4260 EP - 4269 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Hermann, Gloria A1 - Jessen, Holly A1 - Gokarn, Ravi R. T1 - Two beta-alanyl-CoA:ammonia lyases in Clostridium propionicum / Herrmann , G. ; Selmer, T. ; Jessen, HJ. ; Gokarn, RR. ; Selifonova, O. ; Gort , SJ. ; , Buckel, W. JF - The FEBS Journal. 272 (2005), H. 3 Y1 - 2005 SN - 1742-464X SP - 813 EP - 821 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Andrei, Paula I. A1 - Pierik, Antonio J. A1 - Zauner, Stefan T1 - Subunit composition of the glycyl radical enzyme p-hydroxyphenylacetate decarboxylase. A small subunit, HpdC, is essential for catalytic activity / Andrei, PI. ; Pierik, AJ. ; Zauner , S. ; Andrei-Selmer, LC. ; Selmer, T. JF - European Journal of Biochemistry. 271 (2004), H. 11 Y1 - 2004 SN - 0014-2956 SP - 2225 EP - 2230 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Hetzel, Marc A1 - Brock, Matthias A1 - Pierik, Antonio J. T1 - Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein / Hetzel, Marc ; Brock, Matthias ; Selmer, Thorsten, Pierik, Antonio J. ; Golding, Bernard T. ; Buckel, Wolfgang JF - European Journal of Biochemistry. 270 (2003), H. 5 Y1 - 2003 SN - 0014-2956 SP - 902 EP - 910 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Willanzheimer, Angela A1 - Hetzel, Marc T1 - Propionate CoA-transferase from Clostridium propionicum. Cloning of the gene and identification of glutamate 324 at the active site JF - European Journal of Biochemistry. 269 (2002), H. 1 Y1 - 2002 SN - 0014-2956 SP - 372 EP - 380 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Andrei, Paula I. T1 - p-Hydroxyphenylacetate decarboxylase from Clostridium difficile. A novel glycyl radical enzyme catalysing the formation of p-cresol JF - European Journal of Biochemistry. 268 (2001), H. 5 Y1 - 2001 SN - 0014-2956 SP - 1363 EP - 1372 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Darley, Dan J. A1 - Clegg, William A1 - Harrington, Ross W. T1 - Stereocontrolled Synthesis of (2R,3S)-2-Methylisocitrate, a Central Intermediate in the Methylcitrate Cycle / Darley, Dan J. ; Selmer, Thorsten ; Clegg, William ; Harrington, Ross W. ; Buckel, Wolfgang ; Golding, Bernardt JF - Helvetica chimica acta. 86 (2003), H. 12 Y1 - 2003 SN - 1522-2675 SP - 3991 EP - 3999 ER - TY - JOUR A1 - Jeromin, Günter Erich A1 - Zoor, Annegreth T1 - A new irreversible enzyme-aided esterification method in organic solvents JF - Biotechnology letters. 30 (2008), H. 5 Y1 - 2008 SN - 1573-6776 SP - 925 EP - 928 ER - TY - JOUR A1 - Mang, Thomas A1 - Hodenius, M. A. J. A1 - Schmitz-Rode, T. A1 - Baumann, M. T1 - Absorption of 10-hydroxycamptothecin into the coat of magnetoliposomes / Hodenius, M. A. J. ; Schmitz-Rode, T. ; Baumann, M. ; Ivoanova, G. ; Wong, J. E. ; Mang, T. ; Haulena, F. ; Soenen, S. J. H. ; De Cuyper, M. JF - Colloids and Surfaces A: Physicochemical and Engineering Aspects. 343 (2009), H. 1-3 Y1 - 2009 SN - 0927-7757 N1 - Colloid and Surface Science for Nanotechnology SP - 20 EP - 23 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Mang, Thomas A1 - Kolz, J. A1 - Goga, N. A1 - Casanova, F. T1 - Spatial localization with single-sided NMR sensors / Kolz, J. ; Goga, N. ; Casanova, F. ; Mang, T. ; Blümich, B. JF - Applied Magnetic Resonance. 32 (2007), H. 1-2 Y1 - 2007 SN - 0937-9347 SP - 171 EP - 184 ER - TY - JOUR A1 - Scherer, Ulrich W. A1 - Jacobi, M. A1 - Castillo, J. A1 - Foerstel, D. H. T1 - Ultra-low-level measurements of 3H and 14C in wines and champagne / Scherer, U. W. ; Jacobi, M. ; Castillo, J. ; Foerstel, D. H. JF - Radiation effects and defects in solids. 164 (2009), H. 5-6 Y1 - 2009 SN - 1042-0150 SP - 382 EP - 385 ER - TY - JOUR A1 - Scherer, Ulrich W. A1 - Santana, H. H. S. A1 - Maier, G. A1 - Rodenas, J. T1 - Analysis of mechanical strength in ceramic pellets of nuclear fuel / Santana, H. H. S. ; Maier, G. ; Scherer, U. W. ; Rodenas, J. JF - Radiation effects and defects in solids. 164 (2009), H. 5-6 Y1 - 2009 SN - 1042-0150 SP - 313 EP - 318 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Balakrishnan, Karthikeyan A1 - Andrei-Selmer, Luminita-Cornelia A1 - Selmer, Thorsten A1 - Bacher, Michael A1 - Dodel, Richard T1 - Comparison of Intravenous Immunoglobulins for Naturally Occurring Autoantibodies against Amyloid-β JF - Journal of Alzheimer's Disease Y1 - 2010 SN - 1387-2877 VL - 20 IS - 1 SP - 135 EP - 143 ER - TY - JOUR A1 - Selmer, Thorsten A1 - Pinkenburg, Olaf T1 - Method of cloning at least one nucleic acid molecule of interest using type IIS restriction endonucleases, and corresponding cloning vectors, kits and system using type IIS restriction endonucleases / Selmer, Thorsten ; Pinkenburg, Olaf Y1 - 2008 N1 - Patent No. WO 2008095927 A1 Aug 14, 2008 ER - TY - JOUR A1 - Elbers, Gereon T1 - Identification of marker peptides in hair for discrimination with regard to species and breed / Koerner, Andrea ; Ring, Maike ; Fabry, Marlies ; Elbers, Gereon ; Moeller, Martin JF - Proceedings of the Aachen-Dresden International Textile Conference, 3rd, Aachen, Germany, Nov. 26-27, 2009 Y1 - 2009 N1 - Aachen-Dresden International Textile Conference ; (3 : ; 2009.11.26-27 : ; Aachen) PB - DWI CY - Aachen ER - TY - JOUR A1 - Mang, Thomas A1 - Kolz, J. A1 - Hunger, K. A1 - Rath, S. T1 - Investigation of self-diffusion processes in ionic hydrogels with a single-sided sensor / Kolz, J. ; Hunger, K. ; Rath, S. ; Mang, T. ; Blümich, B. JF - Magnetic Resonance Imaging. 25 (2007), H. 4 Y1 - 2007 SN - 0730-725X N1 - Proceedings of the Eighth International Bologna Conference on Magnetic Resonance in Porous Media SP - 566 EP - 567 ER - TY - JOUR A1 - Bäcker, Matthias A1 - Beging, Stefan A1 - Biselli, Manfred A1 - Poghossian, Arshak A1 - Wang, J. A1 - Zang, Werner A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Concept for a solid-state multi-parameter sensor system for cell-culture monitoring JF - Electrochimica Acta. 54 (2009), H. 25 Sp. Iss. SI Y1 - 2009 SN - 0013-4686 SP - 6107 EP - 6112 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jeromin, Günter Erich T1 - Superabsorbed alcohol dehydrogenase—a new catalyst for asymmetric reductions JF - Biotechnology Letters. 31 (2009), H. 11 Y1 - 2009 SN - 0141-5492 SP - 1717 EP - 1721 ER - TY - JOUR A1 - Werner, Frederik A1 - Krumbe, Christoph A1 - Schumacher, Katharina A1 - Groebel, Simone A1 - Spelthahn, Heiko A1 - Stellberg, Michael A1 - Wagner, Torsten A1 - Yoshinobu, Tatsuo A1 - Selmer, Thorsten A1 - Keusgen, Michael A1 - Baumann, Marcus A1 - Schöning, Michael Josef T1 - Determination of the extracellular acidification of Escherichia coli by a light-addressable potentiometric sensor JF - Physica status solidi (a) : applications and material science. 208 (2011), H. 6 Y1 - 2011 SN - 1862-6319 SP - 1340 EP - 1344 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Martins, Berta M. A1 - Blaser, Martin A1 - Feliks, Mikolaj A1 - Ullmann, Matthias G. A1 - Buckel, Wolfgang A1 - Selmer, Thorsten T1 - Structural basis for a Kolbe-type decarboxylation catalyzed by a glycyl radical enzyme JF - Journal of the American Chemical Society Y1 - 2011 N1 - Just accepted manuscript SP - 1 EP - 33 PB - ACS Publications CY - Washington, DC ER - TY - JOUR A1 - Schiffels, Johannes A1 - Baumann, Marcus A1 - Selmer, Thorsten T1 - Facile analysis of short-chain fatty acids as 4-nitrophenyl esters in complex anaerobic fermentation samples by high performance liquid chromatography JF - Journal of Chromatography A. 1218 (2011), H. 34 Y1 - 2011 SN - 0021-9673 SP - 5848 EP - 5851 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Srivastava, A. A1 - Singh, V. A1 - Aggarwal, P. A1 - Schneeweiss, F. A1 - Scherer, Ulrich W. A1 - Friedrich, W. T1 - Optical studies of insulating polymers for radiation dose monitoring JF - Indian Journal of Pure & Applied Physics Y1 - 2010 SN - 0019-5596 N1 - Special Issue: SI VL - 48 IS - 11 SP - 782 EP - 786 ER - TY - JOUR A1 - Bäcker, Matthias A1 - Delle, L. A1 - Poghossian, Arshak A1 - Biselli, Manfred A1 - Zang, Werner A1 - Wagner, P. A1 - Schöning, Michael Josef T1 - Electrochemical sensor array for bioprocess monitoring JF - Electrochimica Acta (2011) Y1 - 2011 VL - 56 IS - 26 SP - 9673 EP - 9678 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Aggarwal, Prerna A1 - Singh, Virendra A1 - Singh, Arjun A1 - Scherer, Ulrich W. A1 - Singh, Tejvir A1 - Singla, Madan L. A1 - Srivastava, Alok T1 - Physico-chemical transformations in swift heavy ion modified poly(ethyleneterephthalate) JF - Radiation Physics and Chemistry Y1 - 2011 SN - 0969-806X N1 - In Press, Accepted Manuscript SP - 1 EP - 28 PB - Pergamon Press CY - Oxford ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Michel, Nico A1 - Osen, Wolfram A1 - Freyschmidt, Eva-Jasmin T1 - T cell response to human papillomavirus 16 E7 in mice: comparison of Cr release assay, intracellular IFN-gamma production, ELISPOT and tetramer staining / Michel, Nico ; Öhlschläger, Peter ; Osen, Wolfram ; Freyschmidt, Eva-Jasmin ; Gutöhrlein, Heidrun ; JF - Intervirology. 45 (2002) Y1 - 2002 SN - 1423-0100 SP - 290 EP - 299 ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Osen, Wolfram A1 - Dell, Kerstin A1 - Faath, Stefan T1 - Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6 mice / Öhlschläger, Peter ; Osen, Wolfram ; Dell, Kerstin ; Faath, Stefan ; Garcea Robert L: ; Jochmus, Ingrid ; Müller, Martin, Pawlita, JF - Journal of Virology. 77 (2003), H. 8 Y1 - 2003 SN - 1098-5514 SP - 4635 EP - 4645 ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Corvinus, Florian M. A1 - Orth, Carina A1 - Moriggl, Richard T1 - Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth / Corvinus, Florian, Moriggl, Richard ; Tsareva, Svetlana A. ; Wagner, Stefan ; Pfitzner, Edith B. ; Baus, Daniela ; Kaufmann, Roland : Huber, Luka JF - Neoplasia. 7 (2005), H. 6 Y1 - 2005 SN - 1476-5586 SP - 545 EP - 555 ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Quetting, Michael A1 - Alvarez, Gerardo A1 - Dürst, Matthias A1 - Gissmann, Lutz A1 - Kaufmann, Andreas M. T1 - Enhancement of immunogenicity of a therapeutic cervical cancer DNA-based vaccine by co-application of sequence-optimized genetic adjuvants JF - International Journal of Cancer Y1 - 2009 SN - 1097-0215 VL - 125 IS - 1 SP - 189 EP - 198 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Oosterhuis, Koen A1 - Öhlschläger, Peter A1 - Berg, Joost H. van den A1 - Toebes, Mireille A1 - Gomez, Raquel A1 - Schumacher, Ton N. A1 - Haanen, John B. T1 - Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7 JF - International Journal of Cancer Y1 - 2011 SN - 1097-0215 VL - 129 IS - 2 SP - 397 EP - 406 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Spies, Elmar A1 - Alvarez, Gerardo A1 - Quetting, Michael A1 - Groettrup, Marcus T1 - The combination of TLR-9 adjuvantation and electroporation-mediated delivery enhances in vivo antitumor responses after vaccination with HPV-16 E7 encoding DNA JF - International Journal of Cancer. 128 (2011), H. 2 Y1 - 2011 SN - 1097-0215 SP - 473 EP - 481 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Leurs, Ulrike A1 - Mezo, Gabor A1 - Öhlschläger, Peter A1 - Orban, Erika A1 - Marquard, Andrea A1 - Manea, Marilena T1 - Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety JF - Peptide Science N2 - Bioconjugates containing the GnRH-III hormone decapeptide as a targeting moiety are able to deliver chemotherapeutic agents specifically to cancer cells expressing GnRH receptors, thereby increasing their local efficacy while limiting the peripheral toxicity. However, the number of GnRH receptors on cancer cells is limited and they desensitize under continuous hormone treatment. A possible approach to increase the receptor mediated tumor targeting and consequently the cytostatic effect of the bioconjugates would be the attachment of more than one chemotherapeutic agent to one GnRH-III molecule. Here we report on the design, synthesis and biochemical characterization of multifunctional bioconjugates containing GnRH-III as a targeting moiety and daunorubicin as a chemotherapeutic agent. Two different drug design approaches were pursued. The first one was based on the bifunctional [4Lys]-GnRH-III (Glp-His-Trp-Lys-His-Asp-Trp-Lys-Pro-Gly-NH2) containing two lysine residues in positions 4 and 8, whose ϵ-amino groups were used for the coupling of daunorubicin. In the second drug design, the native GnRH-III (Glp-His-Trp-Ser-His-Asp-Trp-Lys-Pro-Gly-NH2) was used as a scaffold; an additional lysine residue was coupled to the ϵ-amino group of 8Lys in order to generate two free amino groups available for conjugation of daunorubicin. The in vitro stability/degradation of all synthesized compounds was investigated in human serum, as well as in the presence of rat liver lysosomal homogenate. Their cellular uptake was determined on human breast cancer cells and the cytostatic effect was evaluated on human breast, colon and prostate cancer cell lines. Compared with a monofunctional compound, both drug design approaches resulted in multifunctional bioconjugates with increased cytostatic effect. Y1 - 2012 U6 - http://dx.doi.org/10.1002/bip.21640 SN - 1097-0282 VL - 98 IS - 1 SP - 1 EP - 10 PB - Wiley CY - New York, NY ER - TY - JOUR A1 - Manea, Marilena A1 - Leurs, Ulrike A1 - Orban, Erika A1 - Baranyai, Zsuzsa A1 - Öhlschläger, Peter A1 - Marquardt, Andreas A1 - Schulcz, Akos A1 - Tejeda, Miguel T1 - Enhanced Enzymatic Stability and Antitumor Activity of Daunorubicin-GnRH-III Bioconjugates Modified in Position 4 JF - Bioconjugate Chemistry Y1 - 2011 SN - 1520-4812 VL - 22 IS - 7 SP - 1320 EP - 1329 PB - ACS CY - Washington, DC ER - TY - JOUR A1 - Spiess, Elmar A1 - Wilfried, Reichardt A1 - Alvarez, Gerardo A1 - Gottrup, Marcus A1 - Öhlschläger, Peter T1 - An Artificial PAP Gene Breaks Self-tolerance and Promotes Tumor Regression in the TRAMP Model for Prostate Carcinoma JF - Molecular Therapy Y1 - 2011 SN - 1525-0016 VL - 20 IS - 3 SP - 555 EP - 564 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Osen, Wolfram A1 - Peiler, Tanja A1 - Caldeira, Sandra T1 - A DNA vaccine based on a shuffled E7 oncogene of the human papillomavirus type 16 (HPV 16) induces E7-specific cytotoxic T cells but lacks transforming activity / Osen, Wolfram ; Peiler, Tanja ; Öhlschläger, Peter ; Caldeira, Sandra ; Faath, Stefan ; Mich JF - Vaccine. 19 (2001), H. 20 Y1 - 2001 SN - 0264-410X SP - 4276 EP - 4286 ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Steinberg, Thorsten A1 - Sehr, Peter A1 - Osen, Wolfram T1 - Modification of HPV 16 E7 genes: correlation between the level of protein expression and CTL response after immunization of C57BL/6 mice / Steinberg, Thorsten ; Öhlschläger, Peter ; Sehr, Peter ; Osen, Wolfram ; Gissmann, Lutz JF - Vaccine. 23 (2005), H. 9 Y1 - 2005 SN - 0264-410X SP - 1149 EP - 1157 ER - TY - JOUR A1 - Öhlschläger, Peter A1 - Pes, Michaela A1 - Osen, Wolfram A1 - Dürst, Matthias T1 - An improved rearranged Human Papillomavirus Type 16 E7 DNA vaccine candidate (HPV-16 E7SH) induces an E7 wildtype-specific T cell response / Öhlschläger, Peter ; Pes, Michaela ; Osen, Wolfram ; Dürst, Matthias ; Schneider, Achim ; Gissmann, Lutz ; Kaufman JF - Vaccine. 24 (2006), H. 15 Y1 - 2006 SN - 0264-410X SP - 2880 EP - 2893 ER - TY - JOUR A1 - Bäcker, Matthias A1 - Raue, Markus A1 - Schusser, Sebastian A1 - Jeitner, C. A1 - Breuer, L. A1 - Wagner, P. A1 - Poghossian, Arshak A1 - Förster, Arnold A1 - Mang, Thomas A1 - Schöning, Michael Josef T1 - Microfluidic chip with integrated microvalves based on temperature- and pH-responsive hydrogel thin films JF - Physica Status Solidi (a) N2 - Two types of microvalves based on temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and pH-responsive poly(sodium acrylate) (PSA) hydrogel films have been developed and tested. The PNIPAAm and PSA hydrogel films were prepared by means of in situ photopolymerization directly inside the fluidic channel of a microfluidic chip fabricated by combining Si and SU-8 technologies. The swelling/shrinking properties and height changes of the PNIPAAm and PSA films inside the fluidic channel were studied at temperatures of deionized water from 14 to 36 °C and different pH values (pH 3–12) of Titrisol buffer, respectively. Additionally, in separate experiments, the lower critical solution temperature (LCST) of the PNIPAAm hydrogel was investigated by means of a differential scanning calorimetry (DSC) and a surface plasmon resonance (SPR) method. Mass-flow measurements have shown the feasibility of the prepared hydrogel films to work as an on-chip integrated temperature- or pH-responsive microvalve capable to switch the flow channel on/off. Y1 - 2012 U6 - http://dx.doi.org/10.1002/pssa.201100763 SN - 1862-6319 VL - 209 IS - 5 SP - 839 EP - 845 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Aggarwal, P. A1 - Dhiman, S. A1 - Kumar, G. A1 - Scherer, Ulrich W. A1 - Singla, M. L. A1 - Srivastava, A. T1 - Optical study of poly(ethyleneterephthalate) modified by different ionizing radiation dose JF - Indian Journal of Pure and Applied Physics N2 - Thin films of poly(ethyleneterephthalate) [PET]were exposed to radiation dose ranging from 10 to 30 kGy by using gamma rays in the range 12.8-177.8 MGy using swift light ions of hydrogen. There was no effect of the radiation dose on the optical behaviour of PET as a result of exposure to radiation dose up to 30 kGy brought about by gamma rays but a significant decrease in the optical band gap values was observed when PET was exposed to swift light ions of hydrogen. The data obtained are discussed in terms of optical studies carried out on PET using swift heavy ions. Y1 - 2012 SN - 0019-5596 VL - 50 IS - 2 SP - 129 EP - 132 ER - TY - JOUR A1 - Werner, Frederik A1 - Groebel, Simone A1 - Krumbe, Christoph A1 - Wagner, Torsten A1 - Selmer, Thorsten A1 - Yoshinobu, Tatsuo A1 - Baumann, Marcus A1 - Schöning, Michael Josef T1 - Nutrient concentration-sensitive microorganism-based biosensor JF - Physica Status Solidi (a) Y1 - 2012 U6 - http://dx.doi.org/10.1002/pssa.201100801 SN - 1862-6319 VL - 209 IS - 5 SP - 900 EP - 904 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Schiffels, Johannes A1 - Pinkenburg, Olaf A1 - Schelden, Maximilian A1 - Aboulnaga, El-Hussiny A. A. A1 - Baumann, Marcus A1 - Selmer, Thorsten T1 - An innovative cloning platform enables large-scale production and maturation of an oxygen-tolerant [NiFe]-hydrogenase from cupriavidus necator in Escherichia coli JF - PLOS one. 2013 Y1 - 2013 U6 - http://dx.doi.org/10.1371/journal.pone.0068812 SN - 1932-6203 PB - Public Library of Science CY - San Francisco, California ER - TY - JOUR A1 - Abulnaga, El-Hussiny A1 - Pinkenburg, Olaf A1 - Schiffels, Johannes A1 - E-Refai, Ahmed A1 - Buckel, Wolfgang A1 - Selmer, Thorsten T1 - Effect of an Oxygen-Tolerant Bifurcating Butyryl Coenzyme A Dehydrogenase/Electron-Transferring Flavoprotein Complex from Clostridium difficile on Butyrate Production in Escherichia coli JF - Journal of bacteriology Y1 - 2013 SN - 1098-5530 [E-Journal] SN - 0021-9193 [Print] VL - 195 IS - 16 SP - 3704 EP - 3713 ER - TY - JOUR A1 - Winckler, Silvia A1 - Krueger, Rolf A1 - Schnitzler, Thomas A1 - Zang, Werner A1 - Fischer, Rainer A1 - Biselli, Manfred T1 - A sensitive monitoring system for mammalian cell cultivation processes: a PAT approach JF - Bioprocess and biosystems engineering N2 - Biopharmaceuticals such as antibodies are produced in cultivated mammalian cells, which must be monitored to comply with good manufacturing practice. We, therefore, developed a fully automated system comprising a specific exhaust gas analyzer, inline analytics and a corresponding algorithm to precisely determine the oxygen uptake rate, carbon dioxide evolution rate, carbon dioxide transfer rate, transfer quotient and respiratory quotient without interrupting the ongoing cultivation, in order to assess its reproducibility. The system was verified using chemical simulation experiments and was able to measure the respiratory activity of hybridoma cells and DG44 cells (derived from Chinese hamster ovary cells) with satisfactory results at a minimum viable cell density of ~2.0 × 10⁵ cells ml⁻¹. The system was suitable for both batch and fed-batch cultivations in bubble-aerated and membrane-aerated reactors, with and without the control of pH and dissolved oxygen. Y1 - 2014 U6 - http://dx.doi.org/10.1007/s00449-013-1062-8 SN - 1615-7591 (Print) 1615-7605 (Online) VL - 37 IS - 5 SP - 901 EP - 912 PB - Springer CY - Berlin, Heidelberg ER - TY - JOUR A1 - Meyer-Stork, L. Sebastian A1 - Höcker, Hartwig A1 - Berndt, Heinz T1 - Syntheses and reactions of urethanes of cellobiose and cellulose-containing uretdione groups JF - Journal of applied polymer science Y1 - 1992 SN - 1097-4628 VL - 44 IS - 6 SP - 1043 EP - 1049 ER - TY - JOUR A1 - Schnitzler, Thomas T1 - Cultivation of hybridoma cell line CF-10H5 (DSMZ ACC477) JF - Application notes / Sartorius stedim biotech Y1 - 2009 SP - 1 EP - 4 ER - TY - JOUR A1 - Hemmerling, H.-J. A1 - Merschenz-Quack, Angelika A1 - Wunderlich, H. T1 - Crystal structures of indeno[1,2-d]imidazoles. XIth European Crystallographic Meeting, Vienna 1988 JF - Zeitschrift für Kristallographie - Crystalline Materials Y1 - 1988 SN - 2196-7105 (E-Books); 2194-4946 (Print) VL - 185 IS - H. 1-4 SP - 256 ER - TY - JOUR A1 - Müller, Ulrike A1 - Bongaerts, Johannes A1 - Bovenberg, Roel A1 - Jossek, Ralf A1 - Krämer, Marco A1 - Linnemann, J. A1 - Müschen, S. A1 - Ritterbecks, S. A1 - Sprenger, G. A1 - Wubbolts, Marcel T1 - Metabolic engineering to produce fine chemicals in Escherichia coli JF - Mededelingen van de Faculteit Landbouwwetenschappen, Rijksuniversiteit Gent Y1 - 2001 SN - 0035-533x VL - 66 (3a) SP - 215 EP - 217 ER - TY - JOUR A1 - Jossek, Ralf A1 - Bongaerts, Johannes A1 - Sprenger, Georg A. T1 - Characterization of a new feedback-resistant 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase AroF of Escherichia coli JF - FEMS microbiology letters Y1 - 2001 SN - 1574-6968 VL - Vol. 202 IS - Iss. 1 SP - 145 EP - 148 ER - TY - JOUR A1 - Bongaerts, Johannes A1 - Krämer, Marco A1 - Müller, Ulrike A1 - Raeven, Leon A1 - Wubbolts, Marcel T1 - Metabolic engineering for microbial production of aromatic amino acids and derived compounds JF - Metabolic engineering Y1 - 2001 SN - 1096-7184 (E-Journal); 1096-7176 (Print) VL - Vol. 3 IS - Iss. 4 SP - 289 EP - 300 ER - TY - JOUR A1 - Schmitz, M. A1 - Hirsch, E. A1 - Bongaerts, Johannes A1 - Takors, Ralf T1 - Pulse experiments as a prerequisite for the quantification of in vivo enzyme kinetics in aromatic amino acid pathway of Eschericia coli JF - Biotechnology progress Y1 - 2002 SN - 1520-6033 (E-Journal); 8756-7938 (Print) VL - Vol. 18 IS - Iss. 5 SP - 935 EP - 941 ER - TY - JOUR A1 - Bongaerts, Johannes A1 - Bovenberg, Roel A1 - Krämer, Marco A1 - Müller, Ulrike A1 - Raeven, Leon A1 - Wubbolts, Marcel T1 - Metabolic engineering to produce fine chemicals in Escherichia coli JF - Chemie - Ingenieur - Technik (CIT) Y1 - 2002 SN - 1522-2640 (E-Journal); 0009-286X (Print) N1 - Printausg. in der Bibliothek vorhanden: 63 ZS 022 VL - Vol. 74 IS - Iss. 5 SP - 694 ER - TY - JOUR A1 - Gerigk, M. A1 - Bujnicki, R. A1 - Ganpo-Nkwenkwa, E. A1 - Bongaerts, Johannes A1 - Sprenger, G. A1 - Takors, Ralf T1 - Process control for enhanced L-phenylalanine production using different recombinant Escherichia coli strains JF - Biotechnology and bioengineering Y1 - 2002 SN - 1097-0290 (E-Journal); 0006-3592 (Print) VL - Vol. 80 IS - Iss. 7 SP - 746 EP - 754 ER - TY - JOUR A1 - Gerigk, M. A1 - Maaß, D. A1 - Kreutzer, A. A1 - Sprenger, G. A1 - Bongaerts, Johannes A1 - Wubbolts, Marcel A1 - Takors, Ralf T1 - Enhanced pilot-scale fed-batch L-phenylalanine production with recombinant Escherichia coli by fully integrated reactive extraction JF - Bioprocess and biosystems engineering Y1 - 2002 SN - 1432-0797 (E-Journal); 1615-7605 (E-Journal); 0178-515X (Print); 1615-7591 (Print) VL - Vol. 25 IS - Iss. 1 SP - 43 EP - 52 ER - TY - JOUR A1 - Krämer, Marco A1 - Bongaerts, Johannes A1 - Bovenberg, Roel A1 - Kremer, Susanne A1 - Müller, Ulrike A1 - Orf, Sonja A1 - Wubbolts, Marcel A1 - Raeven, Leon T1 - Metabolic engineering for microbial production of shikimic acid JF - Metabolic engineering Y1 - 2003 SN - 1096-7184 (E-Journal); 1096-7176 (Print) VL - Vol. 5 IS - Iss. 4 SP - 277 EP - 283 ER -