TY - JOUR A1 - Artmann, Gerhard A1 - Schmid-Schönbein, H. A1 - Schröder, Susanne A1 - Grebe, R. [u.a.] T1 - Influence of Moxaverine-HCL on Membrane Curvature and Microsieve Filterability of Red Cells after Exposure to Hyperosmolarity and Lactacidosis. Schmid-Schönbein, H.; Schröder, Susanne; Grebe, R.; Artmann, Gerhard Michael, Eschweiler, H; Teitel, P. JF - Arzneimittelforschung. 38 (1988), H. 5 Y1 - 1988 SN - 0004-4172 SP - 710 EP - 716 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Shi, Young de A1 - Agosti, R. A1 - Longhini, E. T1 - A modified casson equation to characterize blood rheology for hypertension. Shi, Young de; Artmann, Gerhard Michael; Agosti, R.; Longhini, E. JF - Clinical Hemorheology Microcirculation. 19 (1998), H. 2 Y1 - 1998 SN - 1386-0291 SP - 115 EP - 127 ER - TY - CHAP A1 - Artmann, Gerhard A1 - Stadler, Andreas M. A1 - Embs, Jan P. A1 - Zaccai, Giuseppe A1 - Büldt, Georg A1 - Digel, Ilya A1 - Temiz Artmann, Aysegül T1 - The crucial role of water in a phase transition of hemoglobin at body temperature : [abstract] N2 - The observation of a temperature transition of hemoglobin occurring at a critical temperature close to body temperature KW - Hämoglobin KW - Erythrozyt KW - Körpertemperatur Y1 - 2010 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Sung, K.-L. Paul A1 - Horn, Thomas A1 - Whittemore, Darren [u.a.] T1 - Micropipette aspiration of human erythrocytes induces echinocytes via membrane phospholipid translocation. Artmann, Gerhard Michael; Sung, K.-L. Paul; Horn, Thomas; Whittemore, Darren; Norwich, Gerald; Chien, Shu JF - Biophysical journal. 72 (1997), H. 3 Y1 - 1997 SN - 1542-0086 SP - 1434 EP - 1441 ER - TY - BOOK A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül A1 - Zhubanova, Azhar A. A1 - Digel, Ilya ED - Artmann, Gerhard ED - Temiz Artmann, Aysegül ED - Zhubanova, Azhar A. ED - Digel, Ilya T1 - Biological, physical and technical basics of cell engineering Y1 - 2018 SN - 978-981-10-7903-0 PB - Springer CY - Singapore ER - TY - JOUR A1 - Artmann, Gerhard A1 - Trzewik, J. A1 - Schmid-Schönbein, G. W. T1 - Investigation on lymphatic endothelial microvalves / Trzewik, J. ; Artmann, G. M. ; Schmid-Schönbein, G. W. JF - Biomedizinische Technik = Biomedical Engineering. 45 (2000), H. s1 Y1 - 2000 SN - 1862-278X SP - 521 EP - 522 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Trzewik, Jürgen A1 - Ates, M. T1 - A novel method to quantify mechanical tension in cell monolayers. Trzewik, Jürgen; Ates, M., Artmann, Gerhard Michael JF - Biomedizinische Technik. 47 (2002), H. Suppl. 1. Pt. 1 Y1 - 2002 SN - 0013-5585 N1 - Druckausgabe unter 63 Z 47 vorhanden SP - 379 EP - 381 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Trzewik, Jürgen A1 - Mallipattu, S. K. A1 - Delano, F. A. [u.a.] T1 - Evidence for a second valve system in Lymphatics: Endothelial Microvalves. Trzewik, Jürgen; Mallipattu, S. K.; Artmann, Gerhard Michael; Delano, F. A.; Schmid-Schonbein, G. W JF - The FASEB Journal. 15 (2001) Y1 - 2001 SN - 1530-6860 SP - 1711 EP - 1717 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Zang, Werner T1 - Fully automatic measurement of rheologic parameters of red blood cells = Laborautomat zur Messung mechanischer Eigenschaften roter Blutzellen JF - Biomedizinische Technik = Biomedical engineering. 35 (1990), H. Suppl. 3 Y1 - 1990 SN - 0013-5585 SP - 94 EP - 96 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Zerlin, Kay A1 - Digel, Ilya T1 - Hemoglobin Senses Body Temperature JF - Bioengineering in Cell and Tissue Research / Artmann, Gerhard M. ; Chien, Shu (Eds.) Y1 - 2008 SN - 978-3-540-75408-4 SP - 415 EP - 447 PB - Springer CY - Berlin ER - TY - JOUR A1 - Artmann, Gerhard A1 - Zerlin, Kay A1 - Digel, Ilya A1 - Stadler, Andreas M. T1 - Physical discontinuities at body temperature in human red blood cells / Artmann, GM ; Zerlin, K ; Digel, I ; Stadler, A ; Zaccai, G ; Temiz, AA JF - Tissue Engineering. 13 (2007), H. 7 Y1 - 2007 SN - 1076-3279 N1 - TERMIS-EU Meeting Abstracts London, UK September 4–7, 2007 SP - 1778 EP - 1778 ER - TY - JOUR A1 - Artmann, Gerhard A1 - Zhou-Stache, J. A1 - Buettner, R. A1 - Mittermayer, C. [u.a.] T1 - Inhibition of TNF-alpha induced cell death in HUVEC and Jurkat cells by protocatechuic acid. Zhou-Stache, J.; Buettner, R.; Artmann, Gerhard Michael; Mittermayer, C.; Bosserhoff, A. K. JF - Medical and Biological Engineering and Computing. 40 (2002), H. 6 Y1 - 2002 SN - 0140-0118 SP - 698 EP - 703 ER - TY - JOUR A1 - Atlas, Glen A1 - Brealey, David A1 - Dhar, Sunil A1 - Dikta, Gerhard A1 - Singer, Meryvn T1 - Additional hemodynamic measurements with an esophageal Doppler monitor: a preliminary report of compliance, force, kinetic energy, and afterload in the clinical setting JF - Journal of clinical monitoring and computing N2 - The esophageal Doppler monitor (EDM) is a minimally-invasive hemodynamic device which evaluates both cardiac output (CO), and fluid status, by estimating stroke volume (SV) and calculating heart rate (HR). The measurement of these parameters is based upon a continuous and accurate approximation of distal thoracic aortic blood flow. Furthermore, the peak velocity (PV) and mean acceleration (MA), of aortic blood flow at this anatomic location, are also determined by the EDM. The purpose of this preliminary report is to examine additional clinical hemodynamic calculations of: compliance (C), kinetic energy (KE), force (F), and afterload (TSVRi). These data were derived using both velocity-based measurements, provided by the EDM, as well as other contemporaneous physiologic parameters. Data were obtained from anesthetized patients undergoing surgery or who were in a critical care unit. A graphical inspection of these measurements is presented and discussed with respect to each patient’s clinical situation. When normalized to each of their initial values, F and KE both consistently demonstrated more discriminative power than either PV or MA. The EDM offers additional applications for hemodynamic monitoring. Further research regarding the accuracy, utility, and limitations of these parameters is therefore indicated. KW - Acceleration KW - Velocity KW - Kinetic energy KW - Force KW - Compliance KW - Afterload KW - Contractility KW - Volume status KW - Esophageal Doppler monitor Y1 - 2012 SN - 1573-2614 U6 - http://dx.doi.org/10.1007/s10877-012-9386-5 IS - 26 SP - 473 EP - 482 PB - Springer Nature CY - London ER - TY - JOUR A1 - Attar, Mandana Hossein Zadeh A1 - Merk, Hans F. A1 - Kotliar, Konstantin A1 - Wurpts, Gerda A1 - Röseler, Stefani A1 - Moll-Slodowy, Silke A1 - Plange, Johann A1 - Baron, Jens Malte A1 - Balakirski, Galina T1 - The CD63 basophil activation test as a diagnostic tool for assessing autoimmunity in patients with chronic spontaneous urticaria JF - European Journal of Dermatology Y1 - 2019 U6 - http://dx.doi.org/10.1684/ejd.2019.3680 VL - 29 IS - 6 SP - 614 EP - 618 ER - TY - JOUR A1 - Auffray, E. A1 - Bruyndonckx, P. A1 - Devroede, O. A1 - Fedorov, A. A1 - Ziemons, Karl T1 - The ClearPET project JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment N2 - The Crystal Clear Collaboration has designed and is building a high-resolution small animal PET scanner. The design is based on the use of the Hamamatsu R7600-M64 multi-anode photomultiplier tube and a LSO/LuYAP phoswich matrix with one to one coupling between the crystals and the photo-detector. The complete system will have 80 PM tubes in four rings with an inner diameter of 137 mm and an axial field of view of 110 mm. The PM pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. Simulations, and measurements a 2×4 module test set-up predict a spatial resolution of 1.5 mm in the centre of the field of view and a sensitivity of 5.9% for a point source in the centre of the field of view. Y1 - 2004 SN - 0168-9002 N1 - Proceedings of the 2nd International Conference on Imaging Technologies in Biomedical Sciences VL - 527 IS - 1-2 SP - 171 EP - 174 ER - TY - CHAP A1 - Augenstein, Eckardt A1 - Herbergs, S. A1 - Kuperjans, Isabel A1 - Lucas, K. ED - Kjelstrup, Signe T1 - Simulation of industrial energy supply systems with integrated cost optimization T2 - Proceedings of ECOS 2005, the 18th International Conference on Efficiency, Cost, Optimization, Simulation, and Environmental Impact of Energy Systems : Trondheim, Norway, June 20 - 22, 2005. - Vol. 2 Y1 - 2005 SN - 82-519-2041-8 N1 - CD-ROM-Ausg. u.d.T.: Shaping our future energy systems SP - 627 EP - 634 PB - Tapir Academic Press CY - Trondheim ER - TY - CHAP A1 - Augenstein, Eckardt A1 - Kuperjans, Isabel A1 - Lucas, K. ED - Tsatsaronis,, Georgios T1 - EUSEBIA - Decision-Support-System for Technical, Economical and Ecological Design and Evaluation of Industrial Energy Systems T2 - ECOS 2002 : proceedings of the 15th International Conference on Efficiency, Costs, Optimization, Simulation and Environmental Impact of Energy Systems, Berlin, Germany July 3 - 5, 2002. - Vol. 1 Y1 - 2002 SN - 3-00-009533-0 SP - 446 EP - 453 PB - Techn. Univ., Inst. for Energy Engineering CY - Berlin ER - TY - CHAP A1 - Auth, Gunnar A1 - Czarnecki, Christian A1 - Bensberg, Frank ED - Draude, Claude ED - Lange, Martin ED - Sick, Bernhard ED - Gesellschaft für Informatik e.V. (GI), T1 - Impact of robotic process automation on enterprise architectures T2 - GI Edition Proceedings Band 295 INFORMATIK 2019, Workshop-Beiträge N2 - The initial idea of Robotic Process Automation (RPA) is the automation of business processes through the presentation layer of existing application systems. For this simple emulation of user input and output by software robots, no changes of the systems and architecture is required. However, considering strategic aspects of aligning business and technology on an enterprise level as well as the growing capabilities of RPA driven by artificial intelligence, interrelations between RPA and Enterprise Architecture (EA) become visible and pose new questions. In this paper we discuss the relationship between RPA and EA in terms of perspectives and implications. As workin- progress we focus on identifying new questions and research opportunities related to RPA and EA. KW - Robotic Process Automation KW - Enterprise Architecture KW - Software Robots Y1 - 2019 SN - 9783885796893 U6 - http://dx.doi.org/10.18420/inf2019_ws05 SN - 1617-5468 N1 - 50 Jahre Gesellschaft für Informatik – Informatik für Gesellschaft. 16. September, Kassel SP - 59 EP - 65 PB - Köllen CY - Bonn ER - TY - JOUR A1 - Ayala, Rafael Ceja A1 - Harris, Isaac A1 - Kleefeld, Andreas A1 - Pallikarakis, Nikolaos T1 - Analysis of the transmission eigenvalue problem with two conductivity parameters JF - Applicable Analysis N2 - In this paper, we provide an analytical study of the transmission eigenvalue problem with two conductivity parameters. We will assume that the underlying physical model is given by the scattering of a plane wave for an isotropic scatterer. In previous studies, this eigenvalue problem was analyzed with one conductive boundary parameter whereas we will consider the case of two parameters. We prove the existence and discreteness of the transmission eigenvalues as well as study the dependence on the physical parameters. We are able to prove monotonicity of the first transmission eigenvalue with respect to the parameters and consider the limiting procedure as the second boundary parameter vanishes. Lastly, we provide extensive numerical experiments to validate the theoretical work. KW - Transmission Eigenvalues KW - Conductive Boundary Condition KW - Inverse Scattering Y1 - 2023 U6 - http://dx.doi.org/10.1080/00036811.2023.2181167 SN - 0003-6811 PB - Taylor & Francis ER - TY - JOUR A1 - Ayed, Anis Haj A1 - Kusterer, Karsten A1 - Funke, Harald A1 - Keinz, Jan T1 - CFD Based Improvement of the DLN Hydrogen Micromix Combustion Technology at Increased Energy Densities JF - American Scientific Research Journal for Engineering, Technology, and Sciences (ASRJETS) N2 - Combined with the use of renewable energy sources for its production, Hydrogen represents a possible alternative gas turbine fuel within future low emission power generation. Due to the large difference in the physical properties of Hydrogen compared to other fuels such as natural gas, well established gas turbine combustion systems cannot be directly applied for Dry Low NOx (DLN) Hydrogen combustion. Thus, the development of DLN combustion technologies is an essential and challenging task for the future of Hydrogen fuelled gas turbines. The DLN Micromix combustion principle for hydrogen fuel has been developed to significantly reduce NOx-emissions. This combustion principle is based on cross-flow mixing of air and gaseous hydrogen which reacts in multiple miniaturized diffusion-type flames. The major advantages of this combustion principle are the inherent safety against flash-back and the low NOx-emissions due to a very short residence time of reactants in the flame region of the micro-flames. The Micromix Combustion technology has been already proven experimentally and numerically for pure Hydrogen fuel operation at different energy density levels. The aim of the present study is to analyze the influence of different geometry parameter variations on the flame structure and the NOx emission and to identify the most relevant design parameters, aiming to provide a physical understanding of the Micromix flame sensitivity to the burner design and identify further optimization potential of this innovative combustion technology while increasing its energy density and making it mature enough for real gas turbine application. The study reveals great optimization potential of the Micromix Combustion technology with respect to the DLN characteristics and gives insight into the impact of geometry modifications on flame structure and NOx emission. This allows to further increase the energy density of the Micromix burners and to integrate this technology in industrial gas turbines. Y1 - 2016 SN - 2313-4402 VL - 26 IS - 3 SP - 290 EP - 303 PB - GSSRR ER - TY - JOUR A1 - Ayed, Anis Haj A1 - Kusterer, Karsten A1 - Funke, Harald A1 - Keinz, Jan A1 - Bohn, D. T1 - CFD based exploration of the dry-low-NOx hydrogen micromix combustion technology at increased energy densities JF - Propulsion and Power Research KW - Micromix combustion KW - Hydrogen gas turbine KW - Hydrogen combustion KW - High hydrogen combustion KW - Dry-low-NOx (DLN) combustion Y1 - 2017 SN - 2212-540X U6 - http://dx.doi.org/10.1016/j.jppr.2017.01.005 VL - 6 IS - 1 SP - 15 EP - 24 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Ayed, Anis Haj A1 - Striegan, Constantin J. D. A1 - Kusterer, Karsten A1 - Funke, Harald A1 - Kazari, M. A1 - Horikawa, Atsushi A1 - Okada, Kunio T1 - Automated design space exploration of the hydrogen fueled "Micromix" combustor technology N2 - Combined with the use of renewable energy sources for its production, Hydrogen represents a possible alternative gas turbine fuel for future low emission power generation. Due to its different physical properties compared to other fuels such as natural gas, well established gas turbine combustion systems cannot be directly applied for Dry Low NOx (DLN) Hydrogen combustion. This makes the development of new combustion technologies an essential and challenging task for the future of hydrogen fueled gas turbines. The newly developed and successfully tested “DLN Micromix” combustion technology offers a great potential to burn hydrogen in gas turbines at very low NOx emissions. Aiming to further develop an existing burner design in terms of increased energy density, a redesign is required in order to stabilise the flames at higher mass flows and to maintain low emission levels. For this purpose, a systematic design exploration has been carried out with the support of CFD and optimisation tools to identify the interactions of geometrical and design parameters on the combustor performance. Aerodynamic effects as well as flame and emission formation are observed and understood time- and cost-efficiently. Correlations between single geometric values, the pressure drop of the burner and NOx production have been identified as a result. This numeric methodology helps to reduce the effort of manufacturing and testing to few designs for single validation campaigns, in order to confirm the flame stability and NOx emissions in a wider operating condition field. Y1 - 2017 N1 - Proceedings of the 1st Global Power and Propulsion Forum GPPF 2017, Jan 16-18, 2017, Zurich, Switzerland SP - 1 EP - 8 ER - TY - CHAP A1 - Azar, Fouad A1 - Digel, Ilya ED - Staat, Manfred ED - Erni, Daniel T1 - Utilization of fluorescence spectroscopy and neural networks in clinical analysis T2 - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen N2 - Fluorescence topography of human urine in combination with learning algorithms can provide a variant pattern recognition method in analytical clinical chemistry and, eventually, diagnosis. Y1 - 2019 SN - 978-3-940402-22-6 U6 - http://dx.doi.org/10.17185/duepublico/48750 SP - 40 EP - 41 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - CHAP A1 - Azat, Seitkhan A1 - Kerimkulova, Almagul R. A1 - Mansurov, Zulkhair A. A1 - Adekenov, Sergazy A1 - Artmann, Gerhard T1 - The Use of Fusicoccin as Anticancer Compound T2 - Carbon Nanomaterials in Biomedicine and the Environment N2 - The problem of creation and use of sorption materials is of current interest for the practice of the modern medicine and agriculture. Practical importance is production of a biostimulant using a carbon sorbent for a significant increase in productivity, which is very relevant for the regions of Kazakhstan. It is known that a plant phytohormone—fusicoccin—in nanogram concentrations transforms cancer cells to the state of apoptosis. In this regard, there is a scientific practical interest in the development of a highly efficient method for producing fusicoccin from extract of germinated wheat seeds. According to the results of computer modeling, cleaning composite components of fusicoccin using microporous carbon adsorbents not suitable as the size of the molecule of fusicoccin more than micropores and the optimum pore size for purification of constituents of fusicoccin was determined by computer simulation. Y1 - 2020 SN - 978-0-429-42864-7 U6 - http://dx.doi.org/10.1201/9780429428647-8 SP - 149 EP - 172 PB - Jenny Stanford Publishing CY - New York ER - TY - JOUR A1 - Baader, Fabian A1 - Boxberg, Marc S. A1 - Chen, Qian A1 - Förstner, Roger A1 - Kowalski, Julia A1 - Dachwald, Bernd T1 - Field-test performance of an ice-melting probe in a terrestrial analogue environment JF - Icarus N2 - Melting probes are a proven tool for the exploration of thick ice layers and clean sampling of subglacial water on Earth. Their compact size and ease of operation also make them a key technology for the future exploration of icy moons in our Solar System, most prominently Europa and Enceladus. For both mission planning and hardware engineering, metrics such as efficiency and expected performance in terms of achievable speed, power requirements, and necessary heating power have to be known. Theoretical studies aim at describing thermal losses on the one hand, while laboratory experiments and field tests allow an empirical investigation of the true performance on the other hand. To investigate the practical value of a performance model for the operational performance in extraterrestrial environments, we first contrast measured data from terrestrial field tests on temperate and polythermal glaciers with results from basic heat loss models and a melt trajectory model. For this purpose, we propose conventions for the determination of two different efficiencies that can be applied to both measured data and models. One definition of efficiency is related to the melting head only, while the other definition considers the melting probe as a whole. We also present methods to combine several sources of heat loss for probes with a circular cross-section, and to translate the geometry of probes with a non-circular cross-section to analyse them in the same way. The models were selected in a way that minimizes the need to make assumptions about unknown parameters of the probe or the ice environment. The results indicate that currently used models do not yet reliably reproduce the performance of a probe under realistic conditions. Melting velocities and efficiencies are constantly overestimated by 15 to 50 % in the models, but qualitatively agree with the field test data. Hence, losses are observed, that are not yet covered and quantified by the available loss models. We find that the deviation increases with decreasing ice temperature. We suspect that this mismatch is mainly due to the too restrictive idealization of the probe model and the fact that the probe was not operated in an efficiency-optimized manner during the field tests. With respect to space mission engineering, we find that performance and efficiency models must be used with caution in unknown ice environments, as various ice parameters have a significant effect on the melting process. Some of these are difficult to estimate from afar. Y1 - 2023 U6 - http://dx.doi.org/10.1016/j.icarus.2023.115852 N1 - Forschungsdaten hierzu: "Performance data of an ice-melting probe from field tests in two different ice environments" (https://opus.bibliothek.fh-aachen.de/opus4/frontdoor/index/index/docId/10890) IS - 409 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Baader, Fabian A1 - Keller, Denis A1 - Lehmann, Raphael A1 - Gerber, Lukas A1 - Reiswich, Martin A1 - Dachwald, Bernd A1 - Förstner, Roger T1 - Operating melting probes for ice penetration under sublimation conditions and in reduced gravity on a sounding rocket T2 - Proceedings of the 24th ESA Symposium on European Rocket and Balloon Programmes and related Research Y1 - 2019 SN - 0379-6566 N1 - 24th PAC Symposium 2019 ER - TY - CHAP A1 - Baader, Fabian A1 - Reiswich, M. A1 - Bartsch, M. A1 - Keller, D. A1 - Tiede, E. A1 - Keck, G. A1 - Demircian, A. A1 - Friedrich, M. A1 - Dachwald, Bernd A1 - Schüller, K. A1 - Lehmann, R. A1 - Chojetzki, R. A1 - Durand, C. A1 - Rapp, L. A1 - Kowalski, Julia A1 - Förstner, R. T1 - VIPER - Student research on extraterrestrical ice penetration technology T2 - Proceedings of the 2nd Symposium on Space Educational Activities N2 - Recent analysis of scientific data from Cassini and earth-based observations gave evidence for a global ocean under a surrounding solid ice shell on Saturn's moon Enceladus. Images of Enceladus' South Pole showed several fissures in the ice shell with plumes constantly exhausting frozen water particles, building up the E-Ring, one of the outer rings of Saturn. In this southern region of Enceladus, the ice shell is considered to be as thin as 2 km, about an order of magnitude thinner than on the rest of the moon. Under the ice shell, there is a global ocean consisting of liquid water. Scientists are discussing different approaches the possibilities of taking samples of water, i.e. by melting through the ice using a melting probe. FH Aachen UAS developed a prototype of maneuverable melting probe which can navigate through the ice that has already been tested successfully in a terrestrial environment. This means no atmosphere and or ambient pressure, low ice temperatures of around 100 to 150K (near the South Pole) and a very low gravity of 0,114 m/s^2 or 1100 μg. Two of these influencing measures are about to be investigated at FH Aachen UAS in 2017, low ice temperature and low ambient pressure below the triple point of water. Low gravity cannot be easily simulated inside a large experiment chamber, though. Numerical simulations of the melting process at RWTH Aachen however are showing a gravity dependence of melting behavior. Considering this aspect, VIPER provides a link between large-scale experimental simulations at FH Aachen UAS and numerical simulations at RWTH Aachen. To analyze the melting process, about 90 seconds of experiment time in reduced gravity and low ambient pressure is provided by the REXUS rocket. In this time frame, the melting speed and contact force between ice and probes are measured, as well as heating power and a two-dimensional array of ice temperatures. Additionally, visual and infrared cameras are used to observe the melting process. Y1 - 2018 SP - 1 EP - 6 ER - TY - CHAP A1 - Bagheri, Mohsen A1 - Schleupen, Josef A1 - Dahmann, Peter A1 - Kallweit, Stephan T1 - A multi-functional device applying for the safe maintenance at high-altitude on wind turbines T2 - 20th International Conference on Composite Materials : Copenhagen, 19 - 24th July 2015 Y1 - 2015 SP - 1 EP - 6 ER - TY - CHAP A1 - Baier, Ralph A1 - Brauner, Philipp A1 - Brillowski, Florian A1 - Dammers, Hannah A1 - Liehner, Luca A1 - Pütz, Sebastian A1 - Schneider, Sebastian A1 - Schollemann, Alexander A1 - Steuer-Dankert, Linda A1 - Vervier, Luisa A1 - Gries, Thomas A1 - Leicht-Scholten, Carmen A1 - Mertens, Alexander A1 - Nagel, Saskia K. A1 - Schuh, Günther A1 - Ziefle, Martina A1 - Nitsch, Verena ED - Brecher, Christian ED - Schuh, Günther ED - van der Alst, Wil ED - Jarke, Matthias ED - Piller, Frank T. ED - Padberg, Melanie T1 - Human-centered work design for the internet of production T2 - Internet of production - fundamentals, applications and proceedings N2 - Like all preceding transformations of the manufacturing industry, the large-scale usage of production data will reshape the role of humans within the sociotechnical production ecosystem. To ensure that this transformation creates work systems in which employees are empowered, productive, healthy, and motivated, the transformation must be guided by principles of and research on human-centered work design. Specifically, measures must be taken at all levels of work design, ranging from (1) the work tasks to (2) the working conditions to (3) the organizational level and (4) the supra-organizational level. We present selected research across all four levels that showcase the opportunities and requirements that surface when striving for human-centered work design for the Internet of Production (IoP). (1) On the work task level, we illustrate the user-centered design of human-robot collaboration (HRC) and process planning in the composite industry as well as user-centered design factors for cognitive assistance systems. (2) On the working conditions level, we present a newly developed framework for the classification of HRC workplaces. (3) Moving to the organizational level, we show how corporate data can be used to facilitate best practice sharing in production networks, and we discuss the implications of the IoP for new leadership models. Finally, (4) on the supra-organizational level, we examine overarching ethical dimensions, investigating, e.g., how the new work contexts affect our understanding of responsibility and normative values such as autonomy and privacy. Overall, these interdisciplinary research perspectives highlight the importance and necessary scope of considering the human factor in the IoP. KW - Responsibility KW - Privacy KW - Digital leadership KW - Best practice sharing KW - Cognitive assistance system KW - Human-robot collaboration KW - Human-centered work design Y1 - 2023 SN - 978-3-030-98062-7 U6 - http://dx.doi.org/10.1007/978-3-030-98062-7_19-1 N1 - Part of the book series: Interdisciplinary Excellence Accelerator Series (IDEAS) SP - 1 EP - 23 PB - Springer CY - Cham ER - TY - JOUR A1 - Balakirski, Galina A1 - Kotliar, Konstantin A1 - Pauly, Karolin J. A1 - Krings, Laura K. A1 - Rübben, Albert A1 - Baron, Jens M. A1 - Schmitt, Laurenz T1 - Surgical Site Infections After Dermatologic Surgery in Immunocompromised Patients: A Single-Center Experience JF - Dermatologic Surgery N2 - BACKGROUND Immunosuppression is often considered as an indication for antibiotic prophylaxis to prevent surgical site infections (SSI) while performing skin surgery. However, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. PATIENTS AND METHODS All patients of the Department of Dermatology and Allergology at the University Hospital of RWTH Aachen in Aachen, Germany, who underwent hospitalization for a dermatologic surgery between June 2016 and January 2017 (6 months), were followed up after surgery until completion of the wound healing process. The follow-up addressed the occurrence of SSI and the need for systemic antibiotics after the operative procedure. Immunocompromised patients were compared with immunocompetent patients. The investigation was conducted as a retrospective analysis of patient records. RESULTS The authors performed 284 dermatologic surgeries in 177 patients. Nineteen percent (54/284) of the skin surgery was performed on immunocompromised patients. The most common indications for surgical treatment were nonmelanoma skin cancer and malignant melanomas. Surgical site infections occurred in 6.7% (19/284) of the cases. In 95% (18/19), systemic antibiotic treatment was needed. Twenty-one percent of all SSI (4/19) were seen in immunosuppressed patients. CONCLUSION According to the authors' data, immunosuppression does not represent a significant risk factor for SSI after dermatologic surgery. However, larger prospective studies are needed to make specific recommendations on the use of antibiotic prophylaxis while performing skin surgery in these patients. The available data on complications after dermatologic surgery have improved over the past years. Particularly, additional risk factors have been identified for surgical site infections (SSI). Purulent surgical sites, older age, involvement of head, neck, and acral regions, and also the involvement of less experienced surgeons have been reported to increase the risk of the SSI after dermatologic surgeries.1 In general, the incidence of SSI after skin surgery is considered to be low.1,2 However, antibiotics in dermatologic surgeries, especially in the perioperative setting, seem to be overused,3,4 particularly regarding developing antibiotic resistances and side effects. Immunosuppression has been recommended to be taken into consideration as an additional indication for antibiotic prophylaxis to prevent SSI after skin surgery in special cases.5,6 However, these recommendations do not specify the exact dermatologic surgeries, and were not specifically developed for dermatologic surgery patients and treatments, but adopted from other surgical fields.6 According to the survey conducted on American College of Mohs Surgery members in 2012, 13% to 29% of the surgeons administered antibiotic prophylaxis to immunocompromised patients to prevent SSI while performing dermatologic surgery on noninfected skin,3 although this was not recommended by Journal of the American Academy of Dermatology Advisory Statement. Indeed, the data on the risk of developing SSI after dermatologic surgery in immunosuppressed patients are limited. However, it is possible that due to the insufficient evidence on the risk of SSI occurrence in this patient group, dermatologic surgeons tend to overuse perioperative antibiotic prophylaxis. To make specific recommendations on the use of antibiotic prophylaxis in immunosuppressed patients in the field of skin surgery, more information about the incidence of SSI after dermatologic surgery in these patients is needed. The aim of this study was to fill this data gap by investigating whether there is an increased risk of SSI after skin surgery in immunocompromised patients compared with immunocompetent patients. Y1 - 2018 U6 - http://dx.doi.org/10.1097/DSS.0000000000001615 IS - 44 (12) SP - 1525 EP - 1536 PB - Wolters Kluwer ER - TY - JOUR A1 - Balakrishnan, Karthikeyan A1 - Andrei-Selmer, Luminita-Cornelia A1 - Selmer, Thorsten A1 - Bacher, Michael A1 - Dodel, Richard T1 - Comparison of Intravenous Immunoglobulins for Naturally Occurring Autoantibodies against Amyloid-β JF - Journal of Alzheimer's Disease Y1 - 2010 SN - 1387-2877 VL - 20 IS - 1 SP - 135 EP - 143 ER - TY - CHAP A1 - Balaskas, Georgios A1 - Hoffmeister, Benno A1 - Butenweg, Christoph A1 - Pilz, Marco A1 - Bauer, Anna ED - Papadrakakis, Manolis ED - Fragiadakis, Michalis T1 - Earthquake early warning and response system based on intelligent seismic and monitoring sensors embedded in a communication platform and coupled with BIM models T2 - 8th ECCOMAS Thematic Conference on Computational Methods in Structural Dynamics and Earthquake Engineering N2 - This paper describes the concept of an innovative, interdisciplinary, user-oriented earthquake warning and rapid response system coupled with a structural health monitoring system (SHM), capable to detect structural damages in real time. The novel system is based on interconnected decentralized seismic and structural health monitoring sensors. It is developed and will be exemplarily applied on critical infrastructures in Lower Rhine Region, in particular on a road bridge and within a chemical industrial facility. A communication network is responsible to exchange information between sensors and forward warnings and status reports about infrastructures’health condition to the concerned recipients (e.g., facility operators, local authorities). Safety measures such as emergency shutdowns are activated to mitigate structural damages and damage propagation. Local monitoring systems of the infrastructures are integrated in BIM models. The visualization of sensor data and the graphic representation of the detected damages provide spatial content to sensors data and serve as a useful and effective tool for the decision-making processes after an earthquake in the region under consideration. KW - early warning and response system KW - interconnected sensor systems KW - seismic structural damage detection via SHM KW - integration SHM in BIM Y1 - 2021 SN - 978-618-85072-5-8 U6 - http://dx.doi.org/10.7712/120121.8539.18855 SN - 2623-3347 N1 - COMPDYN 2021 28-30 June 2021, Streamed from Athens, Greece SP - 987 EP - 998 PB - National Technical University of Athens CY - Athen ER - TY - JOUR A1 - Balewski, J. A1 - Brauksiepe, S. A1 - Hardt, Arno T1 - Threshold measurements at the internal experimental facility COSY-11 / J. Balewski [u.a.] JF - Nuclear physics A. Vol. 626, iss. 1-2 Y1 - 1997 SN - 1873-1554 (E-Journal) ; 0375-9474 (Print) SP - 85 EP - 92 ER - TY - JOUR A1 - Ball, Christopher Stephen A1 - Vögele, Stefan A1 - Grajewski, Matthias A1 - Kuckshinrichs, Wilhelm T1 - E-mobility from a multi-actor point of view: Uncertainties and their impacts JF - Technological Forecasting and Social Change Y1 - 2021 SN - 0040-1625 U6 - http://dx.doi.org/10.1016/j.techfore.2021.120925 VL - 170 IS - Art. 120925 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Ballmann, J. A1 - Raatschen, Hans-Jürgen A1 - Staat, Manfred T1 - High stress intensities in focussing zones of waves N2 - The propagation of mechanical waves in plates of isotropic elastic material is investigated. After a short introduction to the understanding of focussing of stress waves in a plate with a curved boundary the method of characteristics is applied to a plate of hyperelastic material. Using this method the propagation of acceleration waves is discussed. Based on this a numerical difference scheme is developed for solving initial-boundary-value problems and applied to two examples: propagation of a point disturbance in a homogeneously finitely strained non-linear elastic plate and geometrical focussing in al linear elastic plate. KW - Technische Mechanik KW - Wellen KW - mechanical waves Y1 - 1985 U6 - http://dx.doi.org/10.1016/B978-0-444-42520-1.50015-3 ER - TY - CHAP A1 - Ballmann, Josef A1 - Boucke, Alexander A1 - Braun, Carsten T1 - Aeroelastic sensitivity in the transonic regime T2 - Symposium Transsonicum IV : proceedings of the IUTAM symposium held in Göttingen, Germany, 2 - 6 September 2002 / ed. by Helmut Sobieczky. Fluid mechanics and its applications. Vol. 73 Y1 - 2003 SN - 978-94-010-3998-7 SP - 225 EP - 236 PB - Kluwer Academic CY - Dordrecht ER - TY - CHAP A1 - Ballmann, Josef A1 - Dafnis, Athanasios A1 - Braun, Carsten A1 - Korsch, Helge A1 - Reimerdes, Hans-Günther A1 - Braun, Carsten A1 - Ballmann, Josef T1 - The HIRENASD project: High Reynolds number aerostructural dynamics experiments in the European Transonic Wind Tunnel (ETW) T2 - ICAS 2006 proceedings : 25th Congress of the International Council of the Aeronautical Sciences ; Hamburg, Germany, 3 - 8 September, 2006 : 25th International Congress of Aeronautical Sciences Y1 - 2006 SN - 0-9533991-7-6 SP - Paper No. 2006-5.11.2 PB - Optimage CY - Edinburgh ER - TY - JOUR A1 - Bandodkar, Amay J. A1 - Molinnus, Denise A1 - Mirza, Omar A1 - Guinovart, Tomas A1 - Windmiller, Joshua R. A1 - Valdes-Ramirez, Gabriela A1 - Andrade, Francisco J. A1 - Schöning, Michael Josef A1 - Wang, Joseph T1 - Epidermal tattoo potentiometric sodium sensors with wireless signal transduction for continuous non-invasive sweat monitoring JF - Biosensors and bioelectronics N2 - This article describes the fabrication, characterization and application of an epidermal temporary-transfer tattoo-based potentiometric sensor, coupled with a miniaturized wearable wireless transceiver, for real-time monitoring of sodium in the human perspiration. Sodium excreted during perspiration is an excellent marker for electrolyte imbalance and provides valuable information regarding an individual's physical and mental wellbeing. The realization of the new skin-worn non-invasive tattoo-like sensing device has been realized by amalgamating several state-of-the-art thick film, laser printing, solid-state potentiometry, fluidics and wireless technologies. The resulting tattoo-based potentiometric sodium sensor displays a rapid near-Nernstian response with negligible carryover effects, and good resiliency against various mechanical deformations experienced by the human epidermis. On-body testing of the tattoo sensor coupled to a wireless transceiver during exercise activity demonstrated its ability to continuously monitor sweat sodium dynamics. The real-time sweat sodium concentration was transmitted wirelessly via a body-worn transceiver from the sodium tattoo sensor to a notebook while the subjects perspired on a stationary cycle. The favorable analytical performance along with the wearable nature of the wireless transceiver makes the new epidermal potentiometric sensing system attractive for continuous monitoring the sodium dynamics in human perspiration during diverse activities relevant to the healthcare, fitness, military, healthcare and skin-care domains. Y1 - 2014 U6 - http://dx.doi.org/10.1016/j.bios.2013.11.039 SN - 1873-4235 (E-Journal); 0956-5663 (Print) VL - 54 SP - 603 EP - 609 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bank, Bart L. van de A1 - Orzada, Stephan A1 - Smits, Frits A1 - Lagemaat, Miriam W. A1 - Rodgers, Christopher T. A1 - Bitz, Andreas A1 - Scheenen, Tom W. J. T1 - Optimized (31) P MRS in the human brain at 7 T with a dedicated RF coil setup JF - NMR in Biomedicine Y1 - 2015 U6 - http://dx.doi.org/10.1002/nbm.3422 SN - 1099-1492 VL - 28 IS - 11 SP - 1570 EP - 1578 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Bansal, N. K. A1 - Müller, C. A1 - Vieira, M. E. A1 - Faber, Christian A1 - Schwarzer, Klemens T1 - Thermal performance of a rock bed storage system JF - Proceedings : University of Stuttgart, Germany, August 28th until September 1st, 2000 / Terrastock 2000, 8th International Conference on Thermal Energy Storage. Ed.: M. Benner ... - Vol. 1 Y1 - 2000 SN - 3-9805274-1-7 N1 - Terrastock <2000, Stuttgart> ; Institut für Thermodynamik und Wärmetechnik SP - 433 EP - 439 PB - Inst. für Thermodynamik und Wärmetechnik CY - Stuttgart ER - TY - BOOK A1 - Bansal, Narenda K. A1 - Kleemann, Manfred A1 - Meliß, Michael T1 - Renewable energy sources and conversion technology Y1 - 1990 SN - 0-07-460023-0 PB - Tata McGraw-Hill CY - New Delhi [u.a.] ER - TY - JOUR A1 - Barbazán, Paula A1 - Hagenbach, Adelheid A1 - Paulßen, Elisabeth A1 - Abram, Ulrich A1 - Carballo, Rosa A1 - Rodriguez-Hermida, Sabina A1 - Vázquez-López, Ezequiel M. T1 - Tricarbonyl Rhenium(I) and Technetium(I) Complexes with Hydrazones Derived from 4,5-Diazafluoren-9-one and 1,10-Phenanthroline-5,6-dione JF - European Journal of Inorganic Chemistry N2 - Tricarbonylrhenium(I) and -technetium(I) halide (halide = Cl and Br) complexes of ligands derived from 4,5-diazafluoren-9-one (df) and 1,10-phenanthroline-5,6-dione (phen) derivatives of benzoic and 2-hydroxybenzoic acid hydrazides have been prepared. The complexes have been characterized by elemental analysis, MS, IR, 1H NMR and absorption and emission UV/Vis spectroscopic methods. The metal centres (ReI and TcI) are coordinated through the nitrogen imine atoms and establish five-membered chelate rings, whereas the hydrazone groups stand uncoordinated. The 1H NMR spectra suggest the same behaviour in solution on the basis of only marginal variations in the chemical shifts of the hydrazine protons. Y1 - 2010 U6 - http://dx.doi.org/10.1002/ejic.201000522 SN - 1099-0682 IS - 29 SP - 4622 EP - 4630 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Barek, Jiri A1 - Fischer, Jan A1 - Navratil, Tomas A1 - Peckova, Karolina A1 - Yosypchuk, Bogdan T1 - Silver solid amalgam electrodes as sensors for chemical carcinogens N2 - The applicability of differential pulse voltammetry (DPV) and adsorptive stripping voltammetry (AdSV) at a non-toxic meniscus-modified silver solid amalgam electrode (m-AgSAE) for the determination of trace amounts of genotoxic substances was demonstrated on the determination of micromolar and submicromolar concentrations of 3-nitrofluoranthene using methanol - 0.01 mol L-1 NaOH (9:1) mixture as a base electrolyte and of Ostazine Orange using 0.01 mol L-1 NaOH as a base electrolyte. KW - Biosensor KW - Solid amalgam electrodes KW - voltammetry KW - carcinogens KW - 3-nitrofluoranthene KW - Ostazine Orange Y1 - 2006 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1554 ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel T1 - A goodness-of-fit test for the compound Poisson exponential model JF - Journal of Multivariate Analysis N2 - On the basis of bivariate data, assumed to be observations of independent copies of a random vector (S,N), we consider testing the hypothesis that the distribution of (S,N) belongs to the parametric class of distributions that arise with the compound Poisson exponential model. Typically, this model is used in stochastic hydrology, with N as the number of raindays, and S as total rainfall amount during a certain time period, or in actuarial science, with N as the number of losses, and S as total loss expenditure during a certain time period. The compound Poisson exponential model is characterized in the way that a specific transform associated with the distribution of (S,N) satisfies a certain differential equation. Mimicking the function part of this equation by substituting the empirical counterparts of the transform we obtain an expression the weighted integral of the square of which is used as test statistic. We deal with two variants of the latter, one of which being invariant under scale transformations of the S-part by fixed positive constants. Critical values are obtained by using a parametric bootstrap procedure. The asymptotic behavior of the tests is discussed. A simulation study demonstrates the performance of the tests in the finite sample case. The procedure is applied to rainfall data and to an actuarial dataset. A multivariate extension is also discussed. KW - Bootstrapping KW - Collective risk model Y1 - 2022 U6 - http://dx.doi.org/10.1016/j.jmva.2022.105154 SN - 0047-259X SN - 1095-7243 VL - 195 IS - Article 105154 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel T1 - On Hotelling’s T² test in a special paired sample case JF - Communications in Statistics - Theory and Methods N2 - In a special paired sample case, Hotelling’s T² test based on the differences of the paired random vectors is the likelihood ratio test for testing the hypothesis that the paired random vectors have the same mean; with respect to a special group of affine linear transformations it is the uniformly most powerful invariant test for the general alternative of a difference in mean. We present an elementary straightforward proof of this result. The likelihood ratio test for testing the hypothesis that the covariance structure is of the assumed special form is derived and discussed. Applications to real data are given. KW - complete block symmetry KW - Hotelling’s T² test KW - likelihood ratio test KW - uniformly most powerful invariant test Y1 - 2017 U6 - http://dx.doi.org/10.1080/03610926.2017.1408828 SN - 1532-415X VL - 48 IS - 2 SP - 257 EP - 267 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel T1 - Hotelling’s T² tests in paired and independent survey samples: An efficiency comparison JF - Journal of Multivariate Analysis N2 - Hotelling’s T² tests in paired and independent survey samples are compared using the traditional asymptotic efficiency concepts of Hodges–Lehmann, Bahadur and Pitman, as well as through criteria based on the volumes of corresponding confidence regions. Conditions characterizing the superiority of a procedure are given in terms of population canonical correlation type coefficients. Statistical tests for checking these conditions are developed. Test statistics based on the eigenvalues of a symmetrized sample cross-covariance matrix are suggested, as well as test statistics based on sample canonical correlation type coefficients. Y1 - 2017 U6 - http://dx.doi.org/10.1016/j.jmva.2016.11.004 SN - 0047-259X VL - 2017 IS - 154 SP - 177 EP - 198 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel T1 - On an independence test approach to the goodness-of-fit problem JF - Journal of Multivariate Analysis N2 - Let X₁,…,Xₙ be independent and identically distributed random variables with distribution F. Assuming that there are measurable functions f:R²→R and g:R²→R characterizing a family F of distributions on the Borel sets of R in the way that the random variables f(X₁,X₂),g(X₁,X₂) are independent, if and only if F∈F, we propose to treat the testing problem H:F∈F,K:F∉F by applying a consistent nonparametric independence test to the bivariate sample variables (f(Xᵢ,Xⱼ),g(Xᵢ,Xⱼ)),1⩽i,j⩽n,i≠j. A parametric bootstrap procedure needed to get critical values is shown to work. The consistency of the test is discussed. The power performance of the procedure is compared with that of the classical tests of Kolmogorov–Smirnov and Cramér–von Mises in the special cases where F is the family of gamma distributions or the family of inverse Gaussian distributions. KW - Goodness-of-fit test KW - Independence test KW - Parametric bootstrap KW - Vapnik–Čhervonenkis class KW - Gamma distribution Y1 - 2015 U6 - http://dx.doi.org/10.1016/j.jmva.2015.05.013 SN - 0047-259X VL - 2015 IS - 140 SP - 193 EP - 208 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel T1 - On an asymptotic relative efficiency concept based on expected volumes of confidence regions JF - Statistics - A Journal of Theoretical and Applied Statistic N2 - The paper deals with an asymptotic relative efficiency concept for confidence regions of multidimensional parameters that is based on the expected volumes of the confidence regions. Under standard conditions the asymptotic relative efficiencies of confidence regions are seen to be certain powers of the ratio of the limits of the expected volumes. These limits are explicitly derived for confidence regions associated with certain plugin estimators, likelihood ratio tests and Wald tests. Under regularity conditions, the asymptotic relative efficiency of each of these procedures with respect to each one of its competitors is equal to 1. The results are applied to multivariate normal distributions and multinomial distributions in a fairly general setting. KW - Volume of confidence regions KW - asymptotic relative efficiency KW - likelihood ratio test KW - multivariate normal distribution KW - multinomial distribution Y1 - 2019 U6 - http://dx.doi.org/10.1080/02331888.2019.1683560 SN - 1029-4910 VL - 53 IS - 6 SP - 1396 EP - 1436 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel A1 - Thiele, Jan Philipp T1 - Statistical inference for L²-distances to uniformity JF - Computational Statistics N2 - The paper deals with the asymptotic behaviour of estimators, statistical tests and confidence intervals for L²-distances to uniformity based on the empirical distribution function, the integrated empirical distribution function and the integrated empirical survival function. Approximations of power functions, confidence intervals for the L²-distances and statistical neighbourhood-of-uniformity validation tests are obtained as main applications. The finite sample behaviour of the procedures is illustrated by a simulation study. KW - Integrated empirical distribution (survival) function KW - Goodness-of-fit tests for uniformity KW - Numerical inversion of Laplace transforms KW - Coverage probability KW - Equivalence test Y1 - 2018 U6 - http://dx.doi.org/10.1007/s00180-018-0820-0 SN - 1613-9658 VL - 2018 IS - 33 SP - 1863 EP - 1896 PB - Springer CY - Berlin ER - TY - CHAP A1 - Barnat, Miriam A1 - Bosse, Elke T1 - The challenge of creating meta-inferences: Combining data representing institutional and individual perspectives on first-year support in higher education T2 - 9th Conference on Social Science Methodology of the International Sociological Association, Leicester, UK Y1 - 2016 N1 - RC33 Conference 2016 SP - 1 EP - 20 ER - TY - CHAP A1 - Barnat, Miriam A1 - Bosse, Elke A1 - Tight, Malcolm T1 - The Guiding Role of Theory in Mixed-Methods Research: Combining Individual and Institutional Perspectives on the Transition to Higher Education T2 - Theory and Method in Higher Education Research. Vol 3 N2 - The methodological discourse of mixed-methods research offers general procedures to combine quantitative and qualitative methods for investigating complex fields of research such as higher education. However, integrating different methods still poses considerable challenges. To move beyond general recommendations for mixed-methods research, this chapter proposes to discuss methodological issues with respect to a particular research domain. Taking current studies on the transition to higher education as an example, the authors first provide an overview of the potentials and limitations of quantitative and qualitative methods in the research domain. Second, they show the need for a conceptual framework grounded in the theory of the research object to guide the integration of different methods and findings. Finally, an example study that investigates transition with regard to the interplay of the individual student and the institutional context serves to illustrate the guiding role of theory. The framework integrates different theoretical perspectives on transition, informs the selection of the research methods, and defines the nexus of the two strands that constitute the mixed-methods design. As the interplay of individual and context is of concern for teaching and learning in general, the example presented may be fruitful for the wider field of higher education research. KW - Quantitative research KW - Mixed-Methods Research KW - Transition KW - Students KW - Higher education Y1 - 2017 SN - 978-1-78743-222-2 U6 - http://dx.doi.org/10.1108/S2056-375220170000003001 SP - 1 EP - 19 PB - Emerald Publishing Limited ER - TY - CHAP A1 - Baronas, Romas A1 - Ivanauskas, Feliksas A1 - Kulys, Juozas T1 - Mathematical modeling of biosensors based on an array of enzyme microreactors N2 - This paper presents a two-dimensional-in-space mathematical model of biosensors based on an array of enzyme microreactors immobilised on a single electrode. The modeling system acts under amperometric conditions. The microreactors were modeled by particles and by strips. The model is based on the diffusion equations containing a nonlinear term related to the Michaelis-Menten kinetics of the enzymatic reaction. The model involves three regions: an array of enzyme microreactors where enzyme reaction as well as mass transport by diffusion takes place, a diffusion limiting region where only the diffusion takes place, and a convective region, where the analyte concentration is maintained constant. Using computer simulation, the influence of the geometry of the microreactors and of the diffusion region on the biosensor response was investigated. The digital simulation was carried out using the finite difference technique. KW - Biosensor KW - Reaction-diffusion KW - modeling biosensor KW - microreactor Y1 - 2006 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1569 ER - TY - JOUR A1 - Baroud, G. A1 - Wu, J.Z. A1 - Bohner, M A1 - Sponagel, Stefan A1 - Steffen, T. T1 - How to determine the permeability for cement infiltration into osteoporotic cancellous bone JF - Medical Engineering & Physics. 25 (2003), H. 4 N2 - Cement augmentation is an emerging surgical procedure in which bone cement is used to infiltrate and reinforce osteoporotic vertebrae. Although this infiltration procedure has been widely applied, it is performed empirically and little is known about the flow characteristics of cement during the injection process. We present a theoretical and experimental approach to investigate the intertrabecular bone permeability during the infiltration procedure. The cement permeability was considered to be dependent on time, bone porosity, and cement viscosity in our analysis. In order to determine the time-dependent permeability, ten cancellous bone cores were harvested from osteoporotic vertebrae, infiltrated with acrylic cement at a constant flow rate, and the pressure drop across the cores during the infiltration was measured. The viscosity dependence of the permeability was determined based on published experimental data. The theoretical model for the permeability as a function of bone porosity and time was then fit to the testing data. Our findings suggest that the intertrabecular bone permeability depends strongly on time. For instance, the initial permeability (60.89 mm4/N.s) reduced to approximately 63% of its original value within 18 seconds. This study is the first to analyze cement flow through osteoporotic bone. The theoretical and experimental models provided in this paper are generic. Thus, they can be used to systematically study and optimize the infiltration process for clinical practice. KW - Osteoporose KW - Permeabilität KW - Viskose Strömung KW - Viskosität KW - Vertebroplastie KW - Cement infiltration KW - Vertebroplasty KW - Osteoporosis KW - Permeability KW - Experiment KW - Analysis KW - Viscous flow Y1 - 2003 SN - 1350-4533 SP - 283 EP - 288 ER - TY - JOUR A1 - Barsov, S. A1 - Bechstedt, U. A1 - Hardt, Arno T1 - ANKE, a new facility for medium energy hadron physics at COSY-Jülich / S. Barsov [u.a.] JF - Nuclear instruments and methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. Vol. 462, iss. 3 Y1 - 2001 SN - 0167-5087 (Print) ; 0168-9002 (E-journal) SP - 364 EP - 381 ER - TY - JOUR A1 - Bartella, Alexander K. A1 - Kamal, Mohammad A1 - Scholl, Ingrid A1 - Schiffer, Stefan A1 - Steegmann, Julius A1 - Ketelsen, Dominik A1 - Hölzle, Frank W. A1 - Lethaus, Bernd T1 - Virtual reality in preoperative imaging in maxillofacial surgery: implementation of “the next level”? JF - British Journal of Oral and Maxillofacial Surgery Y1 - 2019 U6 - http://dx.doi.org/10.1016/j.bjoms.2019.02.014 SN - 0266-4356 VL - 57 IS - 7 SP - 644 EP - 648 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bassam, Rasha A1 - Artmann, Gerhard A1 - Hescheler, Jürgen A1 - Graef, T. A1 - Temiz Artmann, Aysegül A1 - Porst, Dariusz A1 - Linder, Peter A1 - Kayser, Peter A1 - Arinkin, Vladimir A1 - Gossmann, Matthias A1 - Digel, Ilya T1 - Alterations in human hemoglobin structure related to red blood cell storage N2 - The importance of the availability of stored blood or blood cells, respectively, for urgent transfusion cannot be overestimated. Nowadays, blood storage becomes even more important since blood products are used for epidemiological studies, bio-technical research or banked for transfusion purposes. Thus blood samples must not only be processed, stored, and shipped to preserve their efficacy and safety, but also all parameters of storage must be recorded and reported for Quality Assurance. Therefore, blood banks and clinical research facilities are seeking more accurate, automated means for blood storage and blood processing. KW - Hämoglobin KW - Hämoglobinstruktur KW - Blutzellenlagerung KW - Hemoglobin structure KW - Red blood cell storage Y1 - 2011 ER - TY - CHAP A1 - Bassam, Rasha A1 - Digel, Ilya A1 - Artmann, Gerhard T1 - Effect of nitric oxide on protein thermal stability : [abstract] N2 - As a deduction from these results, we can conclude that proteins mainly in vitro, denaturate totally at a temperature between 57°C -62°C, and they also affected by NO and different ions types. In which mainly, NO cause earlier protein denaturation, which means that, NO has a destabilizing effect on proteins, and also different ions will alter the protein denaturation in which, some ions will cause earlier protein denaturation while others not. KW - Stickstoffmonoxid KW - Proteine KW - Hämoglobin KW - nitric oxide gas KW - protein KW - hemoglobin Y1 - 2009 ER - TY - JOUR A1 - Bassam, Rasha A1 - Digel, Ilya A1 - Hescheler, Jürgen A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard T1 - Effects of spermine NONOate and ATP on protein aggregation: light scattering evidences JF - BMC Biophysics Y1 - 2013 U6 - http://nbn-resolving.de/urn/resolver.pl?10.1186/2046-1682-6-1 SN - 2046-1682 SP - 1 EP - 14 PB - BioMed Central CY - London ER - TY - JOUR A1 - Bassam, Rasha A1 - Hescheler, Jürgen A1 - Temiz Artmann, Aysegül A1 - Artmann, Gerhard A1 - Digel, Ilya T1 - Effects of spermine NONOate and ATP on the thermal stability of hemoglobin JF - BMC Biophysics N2 - Background Minor changes in protein structure induced by small organic and inorganic molecules can result in significant metabolic effects. The effects can be even more profound if the molecular players are chemically active and present in the cell in considerable amounts. The aim of our study was to investigate effects of a nitric oxide donor (spermine NONOate), ATP and sodium/potassium environment on the dynamics of thermal unfolding of human hemoglobin (Hb). The effect of these molecules was examined by means of circular dichroism spectrometry (CD) in the temperature range between 25°C and 70°C. The alpha-helical content of buffered hemoglobin samples (0.1 mg/ml) was estimated via ellipticity change measurements at a heating rate of 1°C/min. Results Major results were: 1) spermine NONOate persistently decreased the hemoglobin unfolding temperature T u irrespectively of the Na + /K + environment, 2) ATP instead increased the unfolding temperature by 3°C in both sodium-based and potassium-based buffers and 3) mutual effects of ATP and NO were strongly influenced by particular buffer ionic compositions. Moreover, the presence of potassium facilitated a partial unfolding of alpha-helical structures even at room temperature. Conclusion The obtained data might shed more light on molecular mechanisms and biophysics involved in the regulation of protein activity by small solutes in the cell. KW - Nitric Oxide Donor KW - NONOate KW - Circular Dichroism KW - Nitric Oxide Y1 - 2012 U6 - http://dx.doi.org/10.1186/2046-1682-5-16 SN - 2046-1682 VL - 5 PB - BioMed Central CY - London ER - TY - CHAP A1 - Baumann, Marcus ED - Hempel, G. T1 - Primary production and phytoplankton growth in the marginal ice zone of the Fram Strait and the interpretation of the field data with autecological experiments (Abstract) T2 - Oceanography and biology of Arctic seas : selected papers from the ICES Symposium on Marine Sciences of the Arctic and Subarctic Regions, held in Santander, 28 - 30 September 1987. (Rapports et procès-verbaux des réunions / Conseil International pour l'Exploration de la Mer ; 188) Y1 - 1989 SP - 128 PB - International Council for the Exploration of the Sea CY - Copenhagen ER - TY - JOUR A1 - Baumann, Marcus A1 - Brandini, Frederico A1 - Staubes, Regina T1 - The influence of light and temperature on carbonspecific DMS release by cultures of Phaeocystis antarctica and three antarctic diatoms / Baumann, Marcus E.M. ; Brandini, Frederico ; Staubes, Regina JF - Marine Chemistry. 45 (1994), H. 1-2 Y1 - 1994 SN - 0304-4203 SP - 129 EP - 136 ER - TY - JOUR A1 - Baumann, Marcus A1 - Goeyens, L. A1 - Semeneh, M. A1 - Elskens, M. T1 - Phytoplankton nutrient utilisation and nutrient signature in the Southern Ocean / Goeyens, L. ; Semeneh, M. ; Baumann, M.E.M. ; Elskens, M. ; Shopova, D. ; Dehairs, F. JF - Journal of Marine Systems. 17 (1998), H. 1-4 Y1 - 1998 SN - 0924-7963 SP - 143 EP - 157 ER - TY - JOUR A1 - Baumann, Marcus A1 - Gradinger, R. T1 - Distribution of Phytoplankton Communities in Relation to the Large Scale Hydrographical Regime in the Fram Strait 1984 / Gradinger, R. ; Baumann, M.E.M. JF - Marine Biology. 111 (1991), H. 2 Y1 - 1991 SN - 0025-3162 SP - 311 EP - 321 ER - TY - JOUR A1 - Baumann, Marcus A1 - Hirche, H.-J. A1 - Kattner, G. A1 - Gradinger, R. T1 - Plankton distribution and the impact of copepod grazing on primary production in Fram Strait, Greenland Sea / Hirche, H.-J. ; Baumann, M.E.M. ; Kattner, G.; Gradinger, R. JF - Journal of Marine Systems. 2 (1991), H. 3-4 Y1 - 1991 SN - 0924-7963 SP - 477 EP - 494 ER - TY - JOUR A1 - Baumann, Marcus A1 - Jahnke, J. T1 - Chemical and Physical Effects on the Shape and Growth of the Diatom Biddulphia sinensis GREVILLE in Batch Cultures: A Contribution to Bioindication in Plankton Ecology / Jahnke, J. ; Baumann, M. JF - Hydrobiological Bulletin . 17 (1983), H. 1 Y1 - 1983 SN - 0165-1404 SP - 5 EP - 20 ER - TY - JOUR A1 - Baumann, Marcus A1 - Lancelot, C. A1 - Brandini, F. A1 - Sakshaug, E. T1 - The taxonomic identity of the cosmopolitan prymnesiophyte Phaeocystis, a morphological and ecophysiological approach / Baumann, M.E.M. ; Lancelot, C. ; Brandini, F. ; Sakshaug, E. ; John M. JF - Journal of Marine Systems. 5 (1994), H. 1 Y1 - 1994 SN - 0924-7963 SP - 5 EP - 22 ER - TY - JOUR A1 - Baumann, Marcus A1 - Lara, R.J. A1 - Hubberten, D.N. A1 - Thomas, D.N. T1 - Dissolved organic matter studies in enclosed systems: Application of hydophobic fractionation for the assessment of organic nitrogen dynamics / Lara, R.J. ; Hubberten, U. ; Thomas, D.N. ; Baumann, M.E.M. ; Kattner, G. JF - Journal of Marine Systems. 13 (1997), H. 1-4 Y1 - 1997 SN - 0924-7963 SP - 155 EP - 161 ER - TY - JOUR A1 - Baumann, Marcus A1 - Rousseau, V. A1 - Vaulot, D. A1 - Casotti, R. T1 - The life cycle of Phaeocystis (Prymnesiophycae): evidence and hypotheses / Rousseau, V. ; Vaulot, D. ; Casotti, R. ; Cariou, V. ; Lenz, J. ; Gunkel, J. ; Baumann, M. JF - Journal of Marine Systems. 5 (1994), H. 1 Y1 - 1994 SN - 0924-7963 SP - 23 EP - 39 ER - TY - JOUR A1 - Baumann, Marcus A1 - Schwarz, Sonja A1 - Kotliar, Konstantin A1 - Eynatten, Maximilian von A1 - Trucksaess, Arno A1 - Burckhardt, Klaus A1 - Lutz, Jens A1 - Heemann, Uwe A1 - Lanzl, Ines T1 - Non-diabetic chronic kidney disease influences retinal microvasculature JF - Kidney and Blood Pressure Research Y1 - 2009 SN - 1423-0143 VL - 32 IS - 6 SP - 428 EP - 433 PB - - ER - TY - JOUR A1 - Baumann, Marcus A1 - Semeneh, M. A1 - Dehairs, F. A1 - Elskens, M. T1 - Nitrogen uptake regime and phytoplankton community structure in the Southern Ocean / Semeneh, M. ; Dehairs, F. ; Elskens, M. ; Baumann, M.E.M. ; Kopczynska, E.E. ; Lancelot, C. ; Goeyens, L. JF - Journal of Marine Systems. 17 (1998), H. 1-4 Y1 - 1998 SN - 0924-7963 SP - 159 EP - 177 ER - TY - JOUR A1 - Baumann, Marcus A1 - Thomas, D. A1 - Gleitz, M. T1 - Efficiency of carbon assimilation and photoacclimation in a small unicellular Chaetoceros species from the Weddel Sea (Antarctica): Influence of temperature and irridiance / Thomas, D. ; Baumann, M.E.M. ; Gleitz, M. JF - Journal of Experimental Marine Biology and Ecology. 157 (1992), H. 2 Y1 - 1992 SN - 0022-0981 SP - 195 EP - 209 ER - TY - JOUR A1 - Baumann, Marcus A1 - Tillmann, U. A1 - Aletsee, L. T1 - Distribution of Carbon Among Photosynthetic End Products in the Bloom-Forming Arctic Diatom Thalassiosira antarctica COMBER / Tillmann, U. ; Baumann, M.E.M. ; Aletsee, L. JF - Polar Biology. 10 (1989), H. 3 Y1 - 1989 SN - 0722-4060 SP - 231 EP - 238 ER - TY - CHAP A1 - Baumann, T. A1 - Teixeira Boura, Cristiano José A1 - Göttsche, Joachim A1 - Hoffschmidt, Bernhard A1 - O'Connell, B. A1 - Schmitz, S. A1 - Zunft, S. T1 - Air/Sand heat exchanger design and materials for solar thermal power plant applications T2 - SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France Y1 - 2010 SP - 146 EP - 147 PB - Soc. OSC CY - Saint Maur ER - TY - CHAP A1 - Baumann, Torsten A1 - Teixeira Boura, Cristiano José A1 - Eckstein, Julian A1 - Dabrowski, Jan A1 - Göttsche, Joachim A1 - Hoffschmidt, Bernhard A1 - Schmitz, Stefan A1 - Zunft, Stefan T1 - Properties of bulk materials for high-temperature air-sand heat exchangers T2 - 30th ISES Biennial Solar World Congress 2011 : Kassel, Germany, 28 August - 2 September 2011. Vol. 2 Y1 - 2012 SN - 978-1-61839-364-7 SP - 1270 EP - 1278 PB - Curran CY - Red Hook, NY ER - TY - CHAP A1 - Baumann, Torsten A1 - Teixeira Boura, Cristiano José A1 - Göttsche, Joachim A1 - Hoffschmidt, Bernhard A1 - Schmitz, Stefan A1 - Zunft, Stefan T1 - Air-sand heat exchanger: materials and flow properties T2 - SolarPACES 2011 : concentrating solar power and chemical energy systems : 20 - 23 September, 2011, Granada, Spain Y1 - 2011 CY - Granada ER - TY - GEN A1 - Baumgartner, Thomas A1 - Wunderlich, Florian A1 - Jaunich, Arthur A1 - Sato, Tomoo A1 - Bundy, Georg A1 - Grießmann, Nadine A1 - Kowalski, Julia A1 - Burghardt, Stefan A1 - Hanebrink, Jörg T1 - Lighting the way: Perspectives on the global lighting market Y1 - 2012 CY - McKinsey ET - 2nd ed. ER - TY - JOUR A1 - Baumgartner, Werner A1 - Fidler, Florian A1 - Weth, Agnes A1 - Habbecke, Martin A1 - Jakob, Peter A1 - Butenweg, Christoph A1 - Böhme, Wolfgang T1 - Investigating the locomotion of the sandfish in desert sand using NMR-Imaging JF - PLOS ONE N2 - The sandfish (Scincus scincus) is a lizard having the remarkable ability to move through desert sand for significant distances. It is well adapted to living in loose sand by virtue of a combination of morphological and behavioural specializations. We investigated the bodyform of the sandfish using 3D-laserscanning and explored its locomotion in loose desert sand using fast nuclear magnetic resonance (NMR) imaging. The sandfish exhibits an in-plane meandering motion with a frequency of about 3 Hz and an amplitude of about half its body length accompanied by swimming-like (or trotting) movements of its limbs. No torsion of the body was observed, a movement required for a digging-behaviour. Simple calculations based on the Janssen model for granular material related to our findings on bodyform and locomotor behaviour render a local decompaction of the sand surrounding the moving sandfish very likely. Thus the sand locally behaves as a viscous fluid and not as a solid material. In this fluidised sand the sandfish is able to “swim” using its limbs. KW - magnetic resonance imaging KW - body limbs KW - swimming KW - lizards KW - deserts Y1 - 2008 U6 - http://dx.doi.org/10.1371/journal.pone.0003309 SN - 1932-6203 VL - 3 IS - 10 PB - Plos CY - San Francisco, California, US ER - TY - THES A1 - Bayer, Robin T1 - Development of a novel in-vitro vascular model for determination of physiological and pathophysiological mechanobiology Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:38-362212 N1 - Dissertation, Universität zu Köln, 2021 PB - Universität zu Köln CY - Köln ER - TY - CHAP A1 - Bayer, Robin A1 - Hescheler, Jürgen A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül ED - Staat, Manfred ED - Erni, Daniel T1 - Treating arterial hypertension in a cell culture well T2 - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW N2 - Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the “Deutsche Bluthochdruck Liga” this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model. In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology. Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching. Y1 - 2019 SN - 978-3-940402-22-6 U6 - http://dx.doi.org/10.17185/duepublico/48750 SP - 5 EP - 6 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - JOUR A1 - Bayer, Robin A1 - Temiz Artmann, Aysegül A1 - Digel, Ilya A1 - Falkenstein, Julia A1 - Artmann, Gerhard A1 - Creutz, Till A1 - Hescheler, Jürgen T1 - Mechano-pharmacological testing of L-Type Ca²⁺ channel modulators via human vascular celldrum model JF - Cellular Physiology and Biochemistry N2 - Background/Aims: This study aimed to establish a precise and well-defined working model, assessing pharmaceutical effects on vascular smooth muscle cell monolayer in-vitro. It describes various analysis techniques to determine the most suitable to measure the biomechanical impact of vasoactive agents by using CellDrum technology. Methods: The so-called CellDrum technology was applied to analyse the biomechanical properties of confluent human aorta muscle cells (haSMC) in monolayer. The cell generated tensions deviations in the range of a few N/m² are evaluated by the CellDrum technology. This study focuses on the dilative and contractive effects of L-type Ca²⁺ channel agonists and antagonists, respectively. We analyzed the effects of Bay K8644, nifedipine and verapamil. Three different measurement modes were developed and applied to determine the most appropriate analysis technique for the study purpose. These three operation modes are called, particular time mode" (PTM), "long term mode" (LTM) and "real-time mode" (RTM). Results: It was possible to quantify the biomechanical response of haSMCs to the addition of vasoactive agents using CellDrum technology. Due to the supplementation of 100nM Bay K8644, the tension increased approximately 10.6% from initial tension maximum, whereas, the treatment with nifedipine and verapamil caused a significant decrease in cellular tension: 10nM nifedipine decreased the biomechanical stress around 6,5% and 50nM verapamil by 2,8%, compared to the initial tension maximum. Additionally, all tested measurement modes provide similar results while focusing on different analysis parameters. Conclusion: The CellDrum technology allows highly sensitive biomechanical stress measurements of cultured haSMC monolayers. The mechanical stress responses evoked by the application of vasoactive calcium channel modulators were quantified functionally (N/m²). All tested operation modes resulted in equal findings, whereas each mode features operation-related data analysis. Y1 - 2020 U6 - http://dx.doi.org/10.33594/000000225 SN - 1421-9778 VL - 54 SP - 371 EP - 383 PB - Cell Physiol Biochem Press CY - Düsseldorf ER - TY - JOUR A1 - Bayon, Arnau A1 - Valero, Daniel A1 - Garcia-Bartual, Rafael A1 - Vallés-Morán, Francisco José A1 - López-Jiménez, P. Amparo T1 - Performance assessment of OpenFOAM and FLOW-3D in the numerical modeling of a low Reynolds number hydraulic jump JF - Environmental Modelling & Software N2 - A comparative performance analysis of the CFD platforms OpenFOAM and FLOW-3D is presented, focusing on a 3D swirling turbulent flow: a steady hydraulic jump at low Reynolds number. Turbulence is treated using RANS approach RNG k-ε. A Volume Of Fluid (VOF) method is used to track the air–water interface, consequently aeration is modeled using an Eulerian–Eulerian approach. Structured meshes of cubic elements are used to discretize the channel geometry. The numerical model accuracy is assessed comparing representative hydraulic jump variables (sequent depth ratio, roller length, mean velocity profiles, velocity decay or free surface profile) to experimental data. The model results are also compared to previous studies to broaden the result validation. Both codes reproduced the phenomenon under study concurring with experimental data, although special care must be taken when swirling flows occur. Both models can be used to reproduce the hydraulic performance of energy dissipation structures at low Reynolds numbers. Y1 - 2016 SN - 1364-8152 U6 - http://dx.doi.org/10.1016/j.envsoft.2016.02.018 VL - 80 SP - 322 EP - 335 PB - Elsevier CY - Amsterdam ER - TY - BOOK A1 - Baüer, Herbert A1 - Gilch, Heinz Gerhard A1 - Rath, Walter A1 - Schümann, Uwe T1 - Moisture-curing polyurethane-based hot-melt compositions = Feuchthärtbare Heisschmelz-Zusammensetzungen auf Polyurethanbasis Y1 - 1990 N1 - EP0386879 18.10.1990 Veröffentlichungstag im Patentblatt ; Volltext recherchierbar über PB - Europäisches Patentamt CY - München ER - TY - CHAP A1 - Bechstedt, U. A1 - Berg, Georg P. A. A1 - Hacker, U. A1 - Hardt, Arno A1 - Hürlimann, W. A1 - Maier, R. A1 - Martin, S. A1 - Meissburger, J. A1 - Römer, J. G. M. A1 - Possen, P. von A1 - Sagefka, T. T1 - BIG KARL and COSY T2 - The art and science of magnet design. A Festschrift in honor of Klaus Halbach. Vol. 1 Y1 - 1995 SP - 19 EP - 28 PB - Lawrence Berkeley Lab., Univ. of California CY - Berkeley, CA. ER - TY - JOUR A1 - Bechstedt, U. A1 - Haas, H. A1 - Hacker, U. A1 - Hardt, Arno A1 - Henn, K. A1 - Martin, S. A1 - Wimmer, J. T1 - Magnets for the German Spallation Source SNQ JF - IEEE transactions on nuclear science. Vol. 32, iss. 5 Y1 - 1985 SN - 1558-1578 (E-Journal); 0018-9499 (Print) SP - 3631 EP - 3633 ER - TY - JOUR A1 - Becht, Alexander A1 - Schollmayer, Curd A1 - Monakhova, Yulia A1 - Holzgrabe, Ulrike T1 - Tracing the origin of paracetamol tablets by near-infrared, mid-infrared, and nuclear magnetic resonance spectroscopy using principal component analysis and linear discriminant analysis JF - Analytical and Bioanalytical Chemistry N2 - Most drugs are no longer produced in their own countries by the pharmaceutical companies, but by contract manufacturers or at manufacturing sites in countries that can produce more cheaply. This not only makes it difficult to trace them back but also leaves room for criminal organizations to fake them unnoticed. For these reasons, it is becoming increasingly difficult to determine the exact origin of drugs. The goal of this work was to investigate how exactly this is possible by using different spectroscopic methods like nuclear magnetic resonance and near- and mid-infrared spectroscopy in combination with multivariate data analysis. As an example, 56 out of 64 different paracetamol preparations, collected from 19 countries around the world, were chosen to investigate whether it is possible to determine the pharmaceutical company, manufacturing site, or country of origin. By means of suitable pre-processing of the spectra and the different information contained in each method, principal component analysis was able to evaluate manufacturing relationships between individual companies and to differentiate between production sites or formulations. Linear discriminant analysis showed different results depending on the spectral method and purpose. For all spectroscopic methods, it was found that the classification of the preparations to their manufacturer achieves better results than the classification to their pharmaceutical company. The best results were obtained with nuclear magnetic resonance and near-infrared data, with 94.6%/99.6% and 98.7/100% of the spectra of the preparations correctly assigned to their pharmaceutical company or manufacturer. KW - IR KW - Manufacturer KW - Linear discriminant analysis KW - Principal component analysis Y1 - 2021 U6 - http://dx.doi.org/10.1007/s00216-021-03249-z SN - 1618-2650 VL - 413 SP - 3107 EP - 3118 PB - Springer Nature ER - TY - JOUR A1 - Beck, Daniel A1 - Buchleitner, Martin A1 - Ferrein, Alexander A1 - Niemüller, Tim A1 - Steinbauer, Gerald T1 - Mostly Harmless & AllemaniACs - mixed innovations Y1 - 2014 SP - 1 EP - 8 ER - TY - JOUR A1 - Beckenbach, Isabel A1 - Scheidweiler, Robert T1 - Perfect ƒ-Matchings and ƒ-Factors in Hypergraphs - A Combinatorial Approach JF - Discrete Mathematics N2 - We prove characterizations of the existence of perfect ƒ-matchings in uniform mengerian and perfect hypergraphs. Moreover, we investigate the ƒ-factor problem in balanced hypergraphs. For uniform balanced hypergraphs we prove two existence theorems with purely combinatorial arguments, whereas for non-uniform balanced hypergraphs we show that the ƒ-factor problem is NP-hard. Y1 - 2016 U6 - http://dx.doi.org/10.1016/j.disc.2017.05.005 SN - 2192-7782 N1 - Als Volltext auch bei ZIB (Zuse Institute Berlin) VL - 240 IS - 10 SP - 2499 EP - 2506 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Becker, C. A1 - Wallang, C. A1 - Artmann, Gerhard A1 - Jakse, G. T1 - Mechanotransduction-bioreactor for tissue engineering of a ureter prosthesis JF - International Journal of Artificial Organs, The Y1 - 2008 SN - 0391-3988 N1 - Abstracts from the XXXV Congress of the European Society for Artificial Organs: 'Towards Future Biomedical Technologies' - ORAL PRESENTATIONS VL - 31 IS - 7 SP - 583 EP - 583 ER - TY - CHAP A1 - Becker, Jörg A1 - Bergener, Philipp A1 - Breuker, Dominic A1 - Delfmann, Patrick A1 - Eggert, Mathias T1 - An Efficient Business Process Compliance Checking Approach T2 - Governance and Sustainability in Information Systems. Managing the Transfer and Diffusion of IT : IFIP WG 8.6 International Working Conference, Hamburg, Germany, September 22-24, 2011. Proceedings Y1 - 2011 U6 - http://dx.doi.org/10.1007/978-3-642-24148-2_19 SP - 282 EP - 287 PB - Springer CY - Berlin, Heidelberg ER - TY - CHAP A1 - Becker, Jörg A1 - Bergener, Philipp A1 - Delfmann, Patrick A1 - Eggert, Mathias A1 - Weiss, Burkhard T1 - Supporting Business Process Compliance in Financial Institutions - A Model-Driven Approach T2 - Proceedings of the 10th International Conference on Wirtschaftsinformatik : 16 - 18 February 2011, Zurich, Switzerland Y1 - 2011 N1 - Wirtschaftsinformatik Proceedings 2011. 75. SP - 355 EP - 364 ER - TY - JOUR A1 - Becker, Jörg A1 - Delfmann, Patrick A1 - Dietrich, Hanns-Alexander A1 - Steinhorst, Matthias A1 - Eggert, Mathias T1 - Business Process Compliance Checking — Applying and Evaluating a Generic Pattern Matching Approach for Conceptual Models in the Financial Sector JF - Information Systems Frontiers N2 - Given the strong increase in regulatory requirements for business processes the management of business process compliance becomes a more and more regarded field in IS research. Several methods have been developed to support compliance checking of conceptual models. However, their focus on distinct modeling languages and mostly linear (i.e., predecessor-successor related) compliance rules may hinder widespread adoption and application in practice. Furthermore, hardly any of them has been evaluated in a real-world setting. We address this issue by applying a generic pattern matching approach for conceptual models to business process compliance checking in the financial sector. It consists of a model query language, a search algorithm and a corresponding modelling tool prototype. It is (1) applicable for all graph-based conceptual modeling languages and (2) for different kinds of compliance rules. Furthermore, based on an applicability check, we (3) evaluate the approach in a financial industry project setting against its relevance for decision support of audit and compliance management tasks. Y1 - 2016 U6 - http://dx.doi.org/10.1007/s10796-014-9529-y SN - 1572-9419 VL - 18 IS - 2 SP - 359 EP - 405 PB - Springer CY - Berlin ER - TY - JOUR A1 - Becker, Jörg A1 - Delfmann, Patrick A1 - Eggert, Mathias A1 - Schwittay, Sebastian T1 - Generalizability and Applicability of Model-Based Business Process Compliance-Checking Approaches — A State-of-the-Art Analysis and Research Roadmap JF - Business Research : BuR N2 - With a steady increase of regulatory requirements for business processes, automation support of compliance management is a field garnering increasing attention in Information Systems research. Several approaches have been developed to support compliance checking of process models. One major challenge for such approaches is their ability to handle different modeling techniques and compliance rules in order to enable widespread adoption and application. Applying a structured literature search strategy, we reflect and discuss compliance-checking approaches in order to provide an insight into their generalizability and evaluation. The results imply that current approaches mainly focus on special modeling techniques and/or a restricted set of types of compliance rules. Most approaches abstain from real-world evaluation which raises the question of their practical applicability. Referring to the search results, we propose a roadmap for further research in model-based business process compliance checking. Y1 - 2012 U6 - http://dx.doi.org/10.1007/BF03342739 SN - 1866-8658 VL - 5 IS - 2 SP - 221 EP - 247 PB - Springer CY - Heidelberg ER - TY - CHAP A1 - Becker, Jörg A1 - Eggert, Mathias A1 - Bruning, Dennis A1 - Saat, Jan T1 - Applicability of Business Process Model Analysis Approaches – A Case Study in Financial Services Consulting T2 - Wirtschaftsinformatik Proceedings 2013 Y1 - 2013 N1 - 11th International Conference on Wirtschaftsinformatik, 27th February – 01st March 2013, Leipzig, Germany SP - 1181 EP - 1195 ER - TY - CHAP A1 - Becker, Jörg A1 - Eggert, Mathias A1 - Fleischer, Stefan A1 - Knackstedt, Ralf T1 - How to Teach Regulatory Compliant Data Warehouse Engineering? T2 - Proceedings of the Nineteenth Americas Conference on Information Systems, Chicago, Illinois, August 15-17, 2013. Y1 - 2013 N1 - AMCIS 2013 Proceedings ER - TY - CHAP A1 - Becker, Jörg A1 - Eggert, Mathias A1 - Heddier, Marcel A1 - Knackstedt, Ralf T1 - Merging Conceptual Modeling and Law for Legally Compliant Information Systems Design - A Framework-Based Research Agenda T2 - 45th Hawaii International Conference on System Sciences 2012 Y1 - 2012 SN - 978-0-7695-4525-7 U6 - http://dx.doi.org/10.1109/HICSS.2012.428 SP - 5241 EP - 5248 ER - TY - CHAP A1 - Becker, Jörg A1 - Eggert, Mathias A1 - Saat, Jan A1 - Dirding, Philipp T1 - The Influence of Regulation on Data Warehouse Engineering – Investigating an IT Consulting Case in the Financial Service Industry T2 - Proceedings of the Nineteenth Americas Conference on Information Systems, Chicago, Illinois, August 15-17, 2013. Y1 - 2013 SP - 1 EP - 8 ER - TY - CHAP A1 - Becker, Jörg A1 - Eggert, Mathias A1 - Schwittay, Sebastian ED - Mattfeld, Dirk Christian T1 - How to Evaluate the Practical Relevance of Business Process Compliance Checking Approaches? T2 - Multikonferenz Wirtschaftsinformatik 2012 - Tagungsband der MKWI 2012 Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:gbv:084-13011115376 SP - 849 EP - 862 PB - Institut für Wirtschaftsinformatik CY - Braunschweig ER - TY - CHAP A1 - Becker, Jörg A1 - Eggert, Mathias A1 - Winkelmann, Axel A1 - Knackstedt, Ralf T1 - Towards a Contingency Theory based Model of the Influence of Regulation on MIS T2 - Proceedings of the Seventeenth Americas Conference on Information Systems, Detroit, Michigan August 4th -7 th 2011 Y1 - 2011 ER - TY - JOUR A1 - Becker, Meike A1 - Frauenrath, Tobias A1 - Hezel, Fabian A1 - Krombach, Gabriele A. A1 - Kremer, Ute A1 - Koppers, Benedikt A1 - Butenweg, Christoph A1 - Goemmel, Andreas A1 - Utting, Jane F. A1 - Schulz-Menger, Jeanette A1 - Niendorf, Thoralf T1 - Comparison of left ventricular function assessment using phonocardiogram- and electrocardiogram-triggered 2D SSFP CINE MR imaging at 1.5 T and 3.0 T JF - European Radiology N2 - Objective: As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to interference from electromagnetic fields (EMF) and to magneto-hydrodynamic (MHD) effects increases and with it the motivation for a CMR triggering alternative. This study explores the suitability of acoustic cardiac triggering (ACT) for left ventricular (LV) function assessment in healthy subjects (n=14). Methods: Quantitative analysis of 2D CINE steady-state free precession (SSFP) images was conducted to compare ACT’s performance with vector ECG (VCG). Endocardial border sharpness (EBS) was examined paralleled by quantitative LV function assessment. Results: Unlike VCG, ACT provided signal traces free of interference from EMF or MHD effects. In the case of correct Rwave recognition, VCG-triggered 2D CINE SSFP was immune to cardiac motion effects—even at 3.0 T. However, VCG-triggered 2D SSFP CINE imaging was prone to cardiac motion and EBS degradation if R-wave misregistration occurred. ACT-triggered acquisitions yielded LV parameters (end-diastolic volume (EDV), endsystolic volume (ESV), stroke volume (SV), ejection fraction (EF) and left ventricular mass (LVM)) comparable with those derived fromVCG-triggered acquisitions (1.5 T: ESVVCG=(56± 17) ml, EDVVCG=(151±32)ml, LVMVCG=(97±27) g, SVVCG=(94± 19)ml, EFVCG=(63±5)% cf. ESVACT= (56±18) ml, EDVACT=(147±36) ml, LVMACT=(102±29) g, SVACT=(91± 22) ml, EFACT=(62±6)%; 3.0 T: ESVVCG=(55±21) ml, EDVVCG=(151±32) ml, LVMVCG=(101±27) g, SVVCG=(96±15) ml, EFVCG=(65±7)% cf. ESVACT=(54±20) ml, EDVACT=(146±35) ml, LVMACT= (101±30) g, SVACT=(92±17) ml, EFACT=(64±6)%). Conclusions: ACT’s intrinsic insensitivity to interference from electromagnetic fields renders KW - Magnetic resonance imaging (MRI) KW - MR-stethoscope KW - Magnetic field strength KW - Left ventriular function KW - Cardiovascular MRI Y1 - 2010 U6 - http://dx.doi.org/10.1007/s00330-009-1676-z SN - 1432-1084 (Onlineausgabe) SN - 0938-7994 (Druckausgabe) VL - 20 SP - 1344 EP - 1355 PB - Springer CY - Berlin ER - TY - THES A1 - Beckmann, Nils T1 - Characterization of the hydrogen-dry-low-Nox-micromix-combustion-principle for hydrogen-methane fuel mixtures KW - Low NOx KW - Hydrogen KW - Combustion KW - Low emission Y1 - 2019 N1 - Dissertation, RMIT University, August 2019 PB - RMIT University CY - Melbourne ER -