TY - JOUR A1 - Kempt, Hendrik A1 - Freyer, Nils A1 - Nagel, Saskia K. T1 - Justice and the normative standards of explainability in healthcare JF - Philosophy & Technology N2 - Providing healthcare services frequently involves cognitively demanding tasks, including diagnoses and analyses as well as complex decisions about treatments and therapy. From a global perspective, ethically significant inequalities exist between regions where the expert knowledge required for these tasks is scarce or abundant. One possible strategy to diminish such inequalities and increase healthcare opportunities in expert-scarce settings is to provide healthcare solutions involving digital technologies that do not necessarily require the presence of a human expert, e.g., in the form of artificial intelligent decision-support systems (AI-DSS). Such algorithmic decision-making, however, is mostly developed in resource- and expert-abundant settings to support healthcare experts in their work. As a practical consequence, the normative standards and requirements for such algorithmic decision-making in healthcare require the technology to be at least as explainable as the decisions made by the experts themselves. The goal of providing healthcare in settings where resources and expertise are scarce might come with a normative pull to lower the normative standards of using digital technologies in order to provide at least some healthcare in the first place. We scrutinize this tendency to lower standards in particular settings from a normative perspective, distinguish between different types of absolute and relative, local and global standards of explainability, and conclude by defending an ambitious and practicable standard of local relative explainability. KW - Clinical decision support systems KW - Justice KW - Medical AI KW - Explainability KW - Normative standards Y1 - 2022 U6 - https://doi.org/10.1007/s13347-022-00598-0 VL - 35 IS - Article number: 100 SP - 1 EP - 19 PB - Springer Nature CY - Berlin ER - TY - JOUR A1 - Stäudle, Benjamin A1 - Seynnes, Olivier A1 - Laps, Guido A1 - Brüggemann, Gert-Peter A1 - Albracht, Kirsten T1 - Altered gastrocnemius contractile behavior in former achilles tendon rupture patients during walking JF - Frontiers in Physiology N2 - Achilles tendon rupture (ATR) remains associated with functional limitations years after injury. Architectural remodeling of the gastrocnemius medialis (GM) muscle is typically observed in the affected leg and may compensate force deficits caused by a longer tendon. Yet patients seem to retain functional limitations during—low-force—walking gait. To explore the potential limits imposed by the remodeled GM muscle-tendon unit (MTU) on walking gait, we examined the contractile behavior of muscle fascicles during the stance phase. In a cross-sectional design, we studied nine former patients (males; age: 45 ± 9 years; height: 180 ± 7 cm; weight: 83 ± 6 kg) with a history of complete unilateral ATR, approximately 4 years post-surgery. Using ultrasonography, GM tendon morphology, muscle architecture at rest, and fascicular behavior were assessed during walking at 1.5 m⋅s–1 on a treadmill. Walking patterns were recorded with a motion capture system. The unaffected leg served as control. Lower limbs kinematics were largely similar between legs during walking. Typical features of ATR-related MTU remodeling were observed during the stance sub-phases corresponding to series elastic element (SEE) lengthening (energy storage) and SEE shortening (energy release), with shorter GM fascicles (36 and 36%, respectively) and greater pennation angles (8° and 12°, respectively). However, relative to the optimal fascicle length for force production, fascicles operated at comparable length in both legs. Similarly, when expressed relative to optimal fascicle length, fascicle contraction velocity was not different between sides, except at the time-point of peak series elastic element (SEE) length, where it was 39 ± 49% lower in the affected leg. Concomitantly, fascicles rotation during contraction was greater in the affected leg during the whole stance-phase, and architectural gear ratios (AGR) was larger during SEE lengthening. Under the present testing conditions, former ATR patients had recovered a relatively symmetrical walking gait pattern. Differences in seen AGR seem to accommodate the profound changes in MTU architecture, limiting the required fascicle shortening velocity. Overall, the contractile behavior of the GM fascicles does not restrict length- or velocity-dependent force potentials during this locomotor task. KW - tendon rupture KW - muscle fascicle behavior KW - walking gait KW - force generation KW - ultrasound imaging Y1 - 2022 U6 - https://doi.org/10.3389/fphys.2022.792576 SN - 1664-042X VL - 13 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Quittmann, Oliver J. A1 - Abel, Thomas A1 - Albracht, Kirsten A1 - Strüder, Heiko K. T1 - Biomechanics of all-out handcycling exercise: kinetics, kinematics and muscular activity of a 15-s sprint test in able-bodied participants JF - Sports Biomechanics N2 - This study aims to quantify the kinematics, kinetics and muscular activity of all-out handcycling exercise and examine their alterations during the course of a 15-s sprint test. Twelve able-bodied competitive triathletes performed a 15-s all-out sprint test in a recumbent racing handcycle that was attached to an ergometer. During the sprint test, tangential crank kinetics, 3D joint kinematics and muscular activity of 10 muscles of the upper extremity and trunk were examined using a power metre, motion capturing and surface electromyography (sEMG), respectively. Parameters were compared between revolution one (R1), revolution two (R2), the average of revolution 3 to 13 (R3) and the average of the remaining revolutions (R4). Shoulder abduction and internal-rotation increased, whereas maximal shoulder retroversion decreased during the sprint. Except for the wrist angles, angular velocity increased for every joint of the upper extremity. Several muscles demonstrated an increase in muscular activation, an earlier onset of muscular activation in crank cycle and an increased range of activation. During the course of a 15-s all-out sprint test in handcycling, the shoulder muscles and the muscles associated to the push phase demonstrate indications for short-duration fatigue. These findings are helpful to prevent injuries and improve performance in all-out handcycling. KW - Handbike KW - sEMG KW - Paralympic sport KW - performance testing KW - high-intensity exercise Y1 - 2022 U6 - https://doi.org/10.1080/14763141.2020.1745266 SN - 1752-6116 (Onlineausgabe) SN - 1476-3141 (Druckausgabe) VL - 21 IS - 10 SP - 1200 EP - 1223 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Angermann, Susanne A1 - Günthner, Roman A1 - Hanssen, Henner A1 - Lorenz, Georg A1 - Braunisch, Matthias C. A1 - Steubl, Dominik A1 - Matschkal, Julia A1 - Kemmner, Stephan A1 - Hausinger, Renate A1 - Block, Zenonas A1 - Haller, Bernhard A1 - Heemann, Uwe A1 - Kotliar, Konstantin A1 - Grimmer, Timo A1 - Schmaderer, Christoph T1 - Cognitive impairment and microvascular function in end-stage renal disease JF - International Journal of Methods in Psychiatric Research (MPR) N2 - Objective Hemodialysis patients show an approximately threefold higher prevalence of cognitive impairment compared to the age-matched general population. Impaired microcirculatory function is one of the assumed causes. Dynamic retinal vessel analysis is a quantitative method for measuring neurovascular coupling and microvascular endothelial function. We hypothesize that cognitive impairment is associated with altered microcirculation of retinal vessels. Methods 152 chronic hemodialysis patients underwent cognitive testing using the Montreal Cognitive Assessment. Retinal microcirculation was assessed by Dynamic Retinal Vessel Analysis, which carries out an examination recording retinal vessels' reaction to a flicker light stimulus under standardized conditions. Results In unadjusted as well as in adjusted linear regression analyses a significant association between the visuospatial executive function domain score of the Montreal Cognitive Assessment and the maximum arteriolar dilation as response of retinal arterioles to the flicker light stimulation was obtained. Conclusion This is the first study determining retinal microvascular function as surrogate for cerebral microvascular function and cognition in hemodialysis patients. The relationship between impairment in executive function and reduced arteriolar reaction to flicker light stimulation supports the involvement of cerebral small vessel disease as contributing factor for the development of cognitive impairment in this patient population and might be a target for noninvasive disease monitoring and therapeutic intervention. KW - cerebral small vessel disease KW - cognitive impairment KW - dialysis KW - retinal vessels Y1 - 2022 U6 - https://doi.org/10.1002/mpr.1909 SN - 1049-8931 (Print) SN - 1557-0657 (Online) VL - 31 IS - 2 SP - 1 EP - 10 PB - Wiley ER - TY - JOUR A1 - Kotliar, Konstantin A1 - Ortner, Marion A1 - Conradi, Anna A1 - Hacker, Patricia A1 - Hauser, Christine A1 - Günthner, Roman A1 - Moser, Michaela A1 - Muggenthaler, Claudia A1 - Diehl-Schmid, Janine A1 - Priller, Josef A1 - Schmaderer, Christoph A1 - Grimmer, Timo T1 - Altered retinal cerebral vessel oscillation frequencies in Alzheimer's disease compatible with impaired amyloid clearance JF - Neurobiology of Aging N2 - Retinal vessels are similar to cerebral vessels in their structure and function. Moderately low oscillation frequencies of around 0.1 Hz have been reported as the driving force for paravascular drainage in gray matter in mice and are known as the frequencies of lymphatic vessels in humans. We aimed to elucidate whether retinal vessel oscillations are altered in Alzheimer's disease (AD) at the stage of dementia or mild cognitive impairment (MCI). Seventeen patients with mild-to-moderate dementia due to AD (ADD); 23 patients with MCI due to AD, and 18 cognitively healthy controls (HC) were examined using Dynamic Retinal Vessel Analyzer. Oscillatory temporal changes of retinal vessel diameters were evaluated using mathematical signal analysis. Especially at moderately low frequencies around 0.1 Hz, arterial oscillations in ADD and MCI significantly prevailed over HC oscillations and correlated with disease severity. The pronounced retinal arterial vasomotion at moderately low frequencies in the ADD and MCI groups would be compatible with the view of a compensatory upregulation of paravascular drainage in AD and strengthen the amyloid clearance hypothesis. KW - Alzheimer's disease KW - Retinal vessel analysis KW - Vasomotions KW - Pulsations KW - Mild cognitive impairment Y1 - 2022 U6 - https://doi.org/10.1016/j.neurobiolaging.2022.08.012 SN - 0197-4580 VL - 120 SP - 117 EP - 127 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Werfel, Stanislas A1 - Günthner, Roman A1 - Hapfelmeier, Alexander A1 - Hanssen, Henner A1 - Kotliar, Konstantin A1 - Heemann, Uwe A1 - Schmaderer, Christoph ED - Guzik, Tomasz J. T1 - Identification of cardiovascular high-risk groups from dynamic retinal vessel signals using untargeted machine learning JF - Cardiovascular Research N2 - Dynamic retinal vessel analysis (DVA) provides a non-invasive way to assess microvascular function in patients and potentially to improve predictions of individual cardiovascular (CV) risk. The aim of our study was to use untargeted machine learning on DVA in order to improve CV mortality prediction and identify corresponding response alterations. KW - Machine learning KW - Retinal vessels KW - Microcirculation KW - Haemodialysis KW - Myocardial infarction and cardiac death Y1 - 2022 U6 - https://doi.org/10.1093/cvr/cvab040 SN - 0008-6363 VL - 118 IS - 2 SP - 612 EP - 621 PB - Oxford University Press CY - Oxford ER - TY - THES A1 - Biewendt, Marcel T1 - Socio-Economic challenges in sustainability and resource management N2 - This dissertation uses in first stage a macroeconomic investigation to examine the dependence, influence and corruption of socio-economic development through effects of sustainability and resource management. The conducted research found that the state's dependence on its citizens decreases when the state's sources of revenue are largely detached and independent of the citizens' financial resources. In this case, financial resources are taxes and duties provided by the citizens. One possible consequence is the restriction of state investment in its citizens. Both the qualitative literature review and the quantitative data analysis revealed a negative correlation between socio-economic development and the resource economy's share of GDP for the period under study. The microeconomic investigation was primarily conducted through an intensive literature review. It was shown that the rebound effect as such is already very well researched. However, it also became clear that avoidance strategies for the rebound effect and links to sustainability initiatives are scarce or non-existent. The need for a redesign of the impact analysis with regard to technological innovations and their influence on resource consumption and resource management has become clear on the basis of the present study. Further, emerging and developing countries in particular, which will be confronted in the foreseeable future not only with the fundamental problems of resource abundance in the overall economic context, but also with the issues of their sustainable use, should be confronted with these problems as early as possible in order to find solutions in a timely manner. KW - Efficiency side-effects KW - Resource-optimization KW - Rebound effect KW - Socio-economics Y1 - 2022 PB - Hungarian University of Agriculture and Life Sciences ER - TY - JOUR A1 - Uysal, Karya A1 - Creutz, Till A1 - Firat, Ipek Seda A1 - Artmann, Gerhard A1 - Teusch, Nicole A1 - Temiz Artmann, Aysegül T1 - Bio-functionalized ultra-thin, large-area and waterproof silicone membranes for biomechanical cellular loading and compliance experiments JF - Polymers N2 - Biocompatibility, flexibility and durability make polydimethylsiloxane (PDMS) membranes top candidates in biomedical applications. CellDrum technology uses large area, <10 µm thin membranes as mechanical stress sensors of thin cell layers. For this to be successful, the properties (thickness, temperature, dust, wrinkles, etc.) must be precisely controlled. The following parameters of membrane fabrication by means of the Floating-on-Water (FoW) method were investigated: (1) PDMS volume, (2) ambient temperature, (3) membrane deflection and (4) membrane mechanical compliance. Significant differences were found between all PDMS volumes and thicknesses tested (p < 0.01). They also differed from the calculated values. At room temperatures between 22 and 26 °C, significant differences in average thickness values were found, as well as a continuous decrease in thicknesses within a 4 °C temperature elevation. No correlation was found between the membrane thickness groups (between 3–4 µm) in terms of deflection and compliance. We successfully present a fabrication method for thin bio-functionalized membranes in conjunction with a four-step quality management system. The results highlight the importance of tight regulation of production parameters through quality control. The use of membranes described here could also become the basis for material testing on thin, viscous layers such as polymers, dyes and adhesives, which goes far beyond biological applications. Y1 - 2022 SN - 2073-4360 VL - 14 IS - 11 SP - 2213 PB - MDPI CY - Basel ER - TY - JOUR A1 - Bergmann, Ole A1 - Götten, Falk A1 - Braun, Carsten A1 - Janser, Frank T1 - Comparison and evaluation of blade element methods against RANS simulations and test data JF - CEAS Aeronautical Journal N2 - This paper compares several blade element theory (BET) method-based propeller simulation tools, including an evaluation against static propeller ground tests and high-fidelity Reynolds-Average Navier Stokes (RANS) simulations. Two proprietary propeller geometries for paraglider applications are analysed in static and flight conditions. The RANS simulations are validated with the static test data and used as a reference for comparing the BET in flight conditions. The comparison includes the analysis of varying 2D aerodynamic airfoil parameters and different induced velocity calculation methods. The evaluation of the BET propeller simulation tools shows the strength of the BET tools compared to RANS simulations. The RANS simulations underpredict static experimental data within 10% relative error, while appropriate BET tools overpredict the RANS results by 15–20% relative error. A variation in 2D aerodynamic data depicts the need for highly accurate 2D data for accurate BET results. The nonlinear BET coupled with XFOIL for the 2D aerodynamic data matches best with RANS in static operation and flight conditions. The novel BET tool PropCODE combines both approaches and offers further correction models for highly accurate static and flight condition results. KW - BET KW - CFD propeller simulation KW - Propeller aerodynamics KW - Actuator disk modelling KW - Propeller performance Y1 - 2022 U6 - https://doi.org/10.1007/s13272-022-00579-1 SN - 1869-5590 (Online) SN - 1869-5582 (Print) N1 - Corresponding author: Ole Bergmann VL - 13 SP - 535 EP - 557 PB - Springer CY - Wien ER - TY - CHAP A1 - Engelmann, Ulrich M. A1 - Baumann, Martin ED - Herbig, Nicola ED - Poppelreuter, Stefan T1 - Moderationsexpertise für QMBs – das Mindset T2 - Qualitätsmanagement im Gesundheitswesen N2 - Teamsitzungen, Arbeitsgruppentreffen, Kickoffs und Meetings – sie alle werden mit dem Ziel durchgeführt, innerhalb einer vorgegebenen Zeitspanne ein gemeinsames Arbeitsziel zu erreichen. Damit die Zielerreichung auch bei komplexeren Arbeitsaufträgen nicht vom Zufall abhängt, empfiehlt es sich, die Leitung des Ablaufs einem Moderator zu übertragen. In diesem Beitrag einer mehrteiligen Serie wird beschrieben, über welches Mindset der Moderator verfügen sollte, welche grundsätzlichen Methoden hilfreich sind und was bei der Onlinemoderation im Besonderen zu beachten ist. Y1 - 2022 SN - 978-3-8249-0714-4 SP - Kapitel 10814 PB - TÜV-Verlag CY - Köln ET - 59. Update ER - TY - CHAP A1 - Maurer, Florian T1 - Framework to provide a simulative comparison of different energy market designs T2 - Energy Informatics N2 - Useful market simulations are key to the evaluation of diferent market designs existing of multiple market mechanisms or rules. Yet a simulation framework which has a comparison of diferent market mechanisms in mind was not found. The need to create an objective view on different sets of market rules while investigating meaningful agent strategies concludes that such a simulation framework is needed to advance the research on this subject. An overview of diferent existing market simulation models is given which also shows the research gap and the missing capabilities of those systems. Finally, a methodology is outlined how a novel market simulation which can answer the research questions can be developed. Y1 - 2022 U6 - https://doi.org/10.1186/s42162-022-00215-6 SN - 2520-8942 N1 - 11th DACH+ Conference on Energy Informatics, 15-16 September 2022, Freiburg, Germany VL - 5 IS - 2, Article number: 12 SP - 18 EP - 20 PB - Springer Nature ER - TY - CHAP A1 - Horikawa, Atsushi A1 - Ashikaga, Mitsugu A1 - Yamaguchi, Masato A1 - Ogino, Tomoyuki A1 - Aoki, Shigeki A1 - Wirsum, Manfred A1 - Funke, Harald A1 - Kusterer, Karsten T1 - Combined heat and power supply demonstration of Micro-Mix Hydrogen Combustion Applied to M1A-17 Gas Turbine T2 - Proceedings of ASME Turbo Expo 2022: Turbomachinery Technical Conference and Exposition (GT2022) (Volume 3A) N2 - Kawasaki Heavy Industries, Ltd. (KHI), Aachen University of Applied Sciences, and B&B-AGEMA GmbH have investigated the potential of low NOx micro-mix (MMX) hydrogen combustion and its application to an industrial gas turbine combustor. Engine demonstration tests of a MMX combustor for the M1A-17 gas turbine with a co-generation system were conducted in the hydrogen-fueled power generation plant in Kobe City, Japan. This paper presents the results of the commissioning test and the combined heat and power (CHP) supply demonstration. In the commissioning test, grid interconnection, loading tests and load cut-off tests were successfully conducted. All measurement results satisfied the Japanese environmental regulation values. Dust and soot as well as SOx were not detected. The NOx emissions were below 84 ppmv at 15 % O2. The noise level at the site boundary was below 60 dB. The vibration at the site boundary was below 45 dB. During the combined heat and power supply demonstration, heat and power were supplied to neighboring public facilities with the MMX combustion technology and 100 % hydrogen fuel. The electric power output reached 1800 kW at which the NOx emissions were 72 ppmv at 15 % O2, and 60 %RH. Combustion instabilities were not observed. The gas turbine efficiency was improved by about 1 % compared to a non-premixed type combustor with water injection as NOx reduction method. During a total equivalent operation time of 1040 hours, all combustor parts, the M1A-17 gas turbine as such, and the co-generation system were without any issues. KW - industrial gas turbine KW - combustor development KW - fuels KW - hydrogen KW - emission Y1 - 2022 SN - 978-0-7918-8599-4 U6 - https://doi.org/10.1115/GT2022-81620 N1 - ASME Turbo Expo 2022: Turbomachinery Technical Conference and Exposition June 13–17, 2022 Rotterdam, Netherlands PB - American Society of Mechanical Engineers CY - Fairfield ER - TY - CHAP A1 - Butenweg, Christoph ED - Vacareanu, Radu ED - Ionescu, Constantin T1 - Seismic design and evaluation of industrial facilities T2 - The Third European Conference on Earthquake Engineering and Seismology N2 - Industrial facilities must be thoroughly designed to withstand seismic actions as they exhibit an increased loss potential due to the possibly wideranging damage consequences and the valuable process engineering equipment. Past earthquakes showed the social and political consequences of seismic damage to industrial facilities and sensitized the population and politicians worldwide for the possible hazard emanating from industrial facilities. However, a holistic approach for the seismic design of industrial facilities can presently neither be found in national nor in international standards. The introduction of EN 1998-4 of the new generation of Eurocode 8 will improve the normative situation with specific seismic design rules for silos, tanks and pipelines and secondary process components. The article presents essential aspects of the seismic design of industrial facilities based on the new generation of Eurocode 8 using the example of tank structures and secondary process components. The interaction effects of the process components with the primary structure are illustrated by means of the experimental results of a shaking table test of a three story moment resisting steel frame with different process components. Finally, an integrated approach of digital plant models based on building information modelling (BIM) and structural health monitoring (SHM) is presented, which provides not only a reliable decision-making basis for operation, maintenance and repair but also an excellent tool for rapid assessment of seismic damage. KW - Industrial facilities KW - Seismic design KW - Tanks KW - EN 1998-4 KW - Structural health monitoring Y1 - 2022 SN - 978-3-031-15103-3 SN - 978-3-031-15106-4 SN - 978-3-031-15104-0 U6 - https://doi.org/10.1007/978-3-031-15104-0 SN - 2524-342X SN - 2524-3438 N1 - 3ECEES - Third European Conference on Earthquake Engineering and Seismology, September 4 – September 9, 2022, Bucharest SP - 449 EP - 464 PB - Springer CY - Cham ER - TY - CHAP A1 - Morandi, Paolo A1 - Butenweg, Christoph A1 - Breis, Khaled A1 - Beyer, Katrin A1 - Magenes, Guido ED - Arion, Christian ED - Scupin, Alexandra ED - Ţigănescu, Alexandru T1 - Behaviour factor q for the seismic design of URM buildings T2 - The Third European Conference on Earthquake Engineering and Seismology N2 - Recent earthquakes showed that low-rise URM buildings following codecompliant seismic design and details behaved in general very well without substantial damages. Although advances in simulation tools make nonlinear calculation methods more readily accessible to designers, linear analyses will still be the standard design method for years to come. The present paper aims to improve the linear seismic design method by providing a proper definition of the q-factor of URM buildings. Values of q-factors are derived for low-rise URM buildings with rigid diaphragms, with reference to modern structural configurations realized in low to moderate seismic areas of Italy and Germany. The behaviour factor components for deformation and energy dissipation capacity and for overstrength due to the redistribution of forces are derived by means of pushover analyses. As a result of the investigations, rationally based values of the behaviour factor q to be used in linear analyses in the range of 2.0 to 3.0 are proposed. KW - unreinforced masonry buildings KW - modern constructions KW - seismic design KW - linear elastic analysis; KW - behaviour factor q Y1 - 2022 SN - 978-973-100-533-1 N1 - 3ECEES - Third European Conference on Earthquake Engineering and Seismology, September 4 – September 9, 2022, Bucharest SP - 1184 EP - 1194 ER - TY - JOUR A1 - Kaulen, Lars A1 - Schwabedal, Justus T. C. A1 - Schneider, Jules A1 - Ritter, Philipp A1 - Bialonski, Stephan T1 - Advanced sleep spindle identification with neural networks JF - Scientific Reports N2 - Sleep spindles are neurophysiological phenomena that appear to be linked to memory formation and other functions of the central nervous system, and that can be observed in electroencephalographic recordings (EEG) during sleep. Manually identified spindle annotations in EEG recordings suffer from substantial intra- and inter-rater variability, even if raters have been highly trained, which reduces the reliability of spindle measures as a research and diagnostic tool. The Massive Online Data Annotation (MODA) project has recently addressed this problem by forming a consensus from multiple such rating experts, thus providing a corpus of spindle annotations of enhanced quality. Based on this dataset, we present a U-Net-type deep neural network model to automatically detect sleep spindles. Our model’s performance exceeds that of the state-of-the-art detector and of most experts in the MODA dataset. We observed improved detection accuracy in subjects of all ages, including older individuals whose spindles are particularly challenging to detect reliably. Our results underline the potential of automated methods to do repetitive cumbersome tasks with super-human performance. Y1 - 2022 U6 - https://doi.org/10.1038/s41598-022-11210-y SN - 2045-2322 N1 - Corresponding author: Stephan Bialonski VL - 12 IS - Article number: 7686 SP - 1 EP - 10 PB - Springer Nature CY - London ER - TY - CHAP A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Razzaque, Mohammed S. T1 - Role of vitamins in maintaining structure and function of intestinal microbiome T2 - Comprehensive Gut Microbiota N2 - The recent advances in microbiology have shed light on understanding the role of vitamins beyond the nutritional range. Vitamins are critical in contributing to healthy biodiversity and maintaining the proper function of gut microbiota. The sharing of vitamins among bacterial populations promotes stability in community composition and diversity; however, this balance becomes disturbed in various pathologies. Here, we overview and analyze the ability of different vitamins to selectively and specifically induce changes in the intestinal microbial community. Some schemes and regularities become visible, which may provide new insights and avenues for therapeutic management and functional optimization of the gut microbiota. KW - Vitamin A KW - Vitamin B KW - Thiamine KW - Riboflavin KW - Niacin Y1 - 2022 SN - 978-0-12-822036-8 U6 - https://doi.org/10.1016/B978-0-12-819265-8.00043-7 SP - 320 EP - 334 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Gkatzogias, Konstantinos A1 - Veljkoviv, Ana A1 - Pohoryles, Daniel A. A1 - Tsionis, Georgios A1 - Bournas, Dionysios A. A1 - Crowley, Helen A1 - Norlén, Hedvig A1 - Butenweg, Christoph A1 - Gervasio, Helena A1 - Manfredi, Vincenzo A1 - Masi, Angelo A1 - Zaharieva, Roumiana ED - Gkatzogias, Konstantinos ED - Tsionis, Georgios T1 - Policy practice and regional impact assessment for building renovation T2 - REEBUILD Integrated Techniques for the Seismic Strengthening & Energy Efficiency of Existing Buildings N2 - The work presented in this report provides scientific support to building renovation policies in the EU by promoting a holistic point of view on the topic. Integrated renovation can be seen as a nexus between European policies on disaster resilience, energy efficiency and circularity in the building sector. An overview of policy measures for the seismic and energy upgrading of buildings across EU Member States identified only a few available measures for combined upgrading. Regulatory framework, financial instruments and digital tools similar to those for energy renovation, together with awareness and training may promote integrated renovation. A framework for regional prioritisation of building renovation was put forward, considering seismic risk, energy efficiency, and socioeconomic vulnerability independently and in an integrated way. Results indicate that prioritisation of building renovation is a multidimensional problem. Depending on priorities, different integrated indicators should be used to inform policies and accomplish the highest relative or most spread impact across different sectors. The framework was further extended to assess the impact of renovation scenarios across the EU with a focus on priority regions. Integrated renovation can provide a risk-proofed, sustainable, and inclusive built environment, presenting an economic benefit in the order of magnitude of the highest benefit among the separate interventions. Furthermore, it presents the unique capability of reducing fatalities and energy consumption at the same time and, depending on the scenario, to a greater extent. Y1 - 2022 SN - 978-92-76-60454-9 U6 - https://doi.org/10.2760/883122 SN - 1831-9424 SP - 1 EP - 68 PB - Publications Office of the European Union CY - Luxembourg ER - TY - CHAP A1 - Weber, Felix A1 - Bomholt, Frederik A1 - Butenweg, Christoph ED - Bergmeister, Konrad ED - Fingerloos, Frank ED - Wörner, Johann-Dietrich T1 - Erdbeben- und Schwingungsschutz von Bauwerken T2 - 2023 BetonKalender: Wasserundurchlässiger Beton, Brückenbau N2 - Dieser Beitrag beschreibt die herkömmlichen Maßnahmen wie die Kapazitätsbemessung der Tragwerksstruktur, die Isolation des Bauwerks mittels Basisisolatoren, die Dämpfungserhöhung der Struktur mittels Inter-Story-Dämpfern und die Schwingungsreduktion mittels Schwingungstilgern gegen Einwirkungen durch Erdbeben, Wind, Verkehr und Personen auf die Bauwerke. Ergänzend wird die erdbebengerechte Auslegung und Isolation von nichttragenden Bauteilen behandelt. Für die betrachteten Systeme werden die Bewegungsdifferenzialgleichungen unter Berücksichtigung der wesentlichen Nichtlinearitäten angegeben. Die vorgestellten Weiterentwicklungen in den Bereichen der Basisisolatoren, Dämpfern und Schwingungstilgern zeigen, dass das modellbasierte Design mittels Simulation ein sehr effektives, ökonomisches und dank der heutigen Computerleistung auch zeiteffizientes Werkzeug darstellt. Y1 - 2022 SN - 9783433611180 SN - 9783433033753 U6 - https://doi.org/10.1002/9783433611180.ch16 N1 - Beton-Kalender, 112. Jahrgang (2023): Wasserundurchlässiger Beton, Brückenbau ausleihbar unter der Sig. 11 XCF 3-2023,2 SP - 779 EP - 859 PB - Ernst & Sohn CY - Berlin ER - TY - CHAP A1 - Eggert, Mathias A1 - Kriska, Melina T1 - Gamification for software development processes – relevant affordances and design principles T2 - Proceedings of the 55th Hawaii International Conference on System Sciences N2 - A Gamified Information System (GIS) implements game concepts and elements, such as affordances and game design principles to motivate people. Based on the idea to develop a GIS to increase the motivation of software developers to perform software quality tasks, the research work at hand aims at investigating relevant requirements from that target group. Therefore, 14 interviews with software development experts are conducted and analyzed. According to the results, software developers prefer the affordances points, narrative storytelling in a multiplayer and a round-based setting. Furthermore, six design principles for the development of a GIS are derived. Y1 - 2022 SN - 978-0-9981331-5-7 U6 - https://doi.org/10.24251/HICSS.2022.200 N1 - Hawaii International Conference on System Sciences (HICSS) 2022, 04.01.2022 – 07.01.2022 SP - 1614 EP - 1623 PB - HICSS Publishing CY - Honolulu ER - TY - JOUR A1 - Hein, Andreas M. A1 - Eubanks, T. Marshall A1 - Lingam, Manasvi A1 - Hibberd, Adam A1 - Fries, Dan A1 - Schneider, Jean A1 - Kervella, Pierre A1 - Kennedy, Robert A1 - Perakis, Nikolaos A1 - Dachwald, Bernd T1 - Interstellar now! Missions to explore nearby interstellar objects JF - Advances in Space Research N2 - The recently discovered first hyperbolic objects passing through the Solar System, 1I/’Oumuamua and 2I/Borisov, have raised the question about near term missions to Interstellar Objects. In situ spacecraft exploration of these objects will allow the direct determination of both their structure and their chemical and isotopic composition, enabling an entirely new way of studying small bodies from outside our solar system. In this paper, we map various Interstellar Object classes to mission types, demonstrating that missions to a range of Interstellar Object classes are feasible, using existing or near-term technology. We describe flyby, rendezvous and sample return missions to interstellar objects, showing various ways to explore these bodies characterizing their surface, dynamics, structure and composition. Their direct exploration will constrain their formation and history, situating them within the dynamical and chemical evolution of the Galaxy. These mission types also provide the opportunity to explore solar system bodies and perform measurements in the far outer solar system. KW - Interstellar objects KW - Trajectories KW - Missions Y1 - 2022 U6 - https://doi.org/10.1016/j.asr.2021.06.052 SN - 0273-1177 VL - 69 IS - 1 SP - 402 EP - 414 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Akimbekov, Nuraly S. A1 - Digel, Ilya A1 - Sherelkhan, Dinara K. A1 - Razzaque, Mohammed S. T1 - Vitamin D and Phosphate Interactions in Health and Disease T2 - Phosphate Metabolism N2 - Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease. KW - Vitamin D KW - PTH KW - Phosphate KW - FGF23 KW - Klotho Y1 - 2022 SN - 978-3-030-91621-3 U6 - https://doi.org/10.1007/978-3-030-91623-7_5 SP - 37 EP - 46 PB - Springer CY - Cham ER - TY - CHAP A1 - Zähl, Philipp M. A1 - Biewendt, Marcel A1 - Wolf, Martin R. A1 - Eggert, Mathias T1 - Requirements for competence developing games in the environment of SE Competence Development T2 - AKWI-Tagungsband zur 35. AKWI-Jahrestagung N2 - Many of today’s factors make software development more and more complex, such as time pressure, new technologies, IT security risks, et cetera. Thus, a good preparation of current as well as future software developers in terms of a good software engineering education becomes progressively important. As current research shows, Competence Developing Games (CDGs) and Serious Games can offer a potential solution. This paper identifies the necessary requirements for CDGs to be conducive in principle, but especially in software engineering (SE) education. For this purpose, the current state of research was summarized in the context of a literature review. Afterwards, some of the identified requirements as well as some additional requirements were evaluated by a survey in terms of subjective relevance. KW - software engineering KW - requirements KW - competence developing games KW - systematic literature review Y1 - 2022 SN - 978-3-95545-409-8 U6 - https://doi.org/10.30844/AKWI_2022_05 N1 - Tagungsband zur 35. Jahrestagung des Arbeitskreises Wirtschaftsinformatik an Hochschulen für Angewandte Wissenschaften im deutschsprachigen Raum (AKWI), 11.09. bis 13.09.2022, Hochschule für Technik und Wirtschaft Berlin (HTW Berlin) und Hochschule für Wirtschaft und Recht Berlin (HWR Berlin) SP - 73 EP - 88 PB - GITO CY - Berlin ER - TY - JOUR A1 - Kubalski, Thomas A1 - Butenweg, Christoph A1 - El-Deib, Khaled ED - Jesse, Dirk T1 - Vereinfachte Berücksichtigung der Rahmentragwirkung in Mauerwerksgebäuden T1 - Simplified consideratioon of framing effects in masonry buildings JF - Bautechnik N2 - Aufgrund der gestiegenen Anforderungen durch höhere Ein-wirkungen aus Wind und Erdbeben ist eine Verbesserung und Optimierung der Berechnungs- und Bemessungsansätze für Mauerwerksbauten erforderlich. Eine bessere Ausnutzung der Tragwerksreserven ist durch die Berücksichtigung der Rah-mentragwirkung mit einer Aktivierung der Deckenscheiben in den Rechenmodellen möglich, die in der Praxis aufgrund der Komplexität der Wand-Decken-Interaktion bislang nicht aus-genutzt wird. Im vorliegenden Aufsatz wird ein vereinfachter Ansatz auf Grundlage der mitwirkenden Plattenbreite von Schubwänden aus Mauerwerk vorgestellt, der die wesentli-chen Einfl ussfaktoren in parametrisierten Tabellen erfasst. Damit steht den Tragwerksplanern ein einfach anwendbares Werkzeug zur Verfügung, um die Rahmentragwirkung in der Mauerwerksbemessung anzusetzen. N2 - Due to the increased requirements resulting from higher wind and earthquake loads, it is necessary to improve and optimise the calculation and design approaches for masonry structures. An important contribution to a better utilisation of the structural load-bearing reserves is the consideration of the framing ef-fects through the activation of the fl oor slabs in the calculation models, which has not been utilised in practice so far due to the complexity of the wall-slab interaction. The paper presents a simplifi ed approach based on the contributory slab width, which captures the essential infl uencing factors in parameter-ised tables. This provides structural engineers with a simple tool to exploit the frame load-bearing effect in masonry design. KW - Rahmentragwirkung KW - Mauerwerksgebäude KW - Wand-Decken-Interaktion KW - Momentenverteilung KW - DIN EN 1996 Y1 - 2022 U6 - https://doi.org/10.1002/bate.202200081 SN - 0932-8351 SN - 1437-0999 VL - 99 IS - 12 SP - 865 EP - 928 PB - Ernst & Sohn CY - Berlin ER - TY - CHAP A1 - Weiss, Christian A1 - Heslenfeld, Jonas A1 - Saewe, Jasmin Kathrin A1 - Bremen, Sebastian A1 - Häfner, Constantin Leon T1 - Investigation on the influence of powder humidity in Laser Powder Bed Fusion (LPBF) T2 - Procedia CIRP 12th CIRP Conference on Photonic Technologies [LANE 2022] N2 - In the Laser Powder Bed Fusion (LPBF) process, parts are built out of metal powder material by exposure of a laser beam. During handling operations of the powder material, several influencing factors can affect the properties of the powder material and therefore directly influence the processability during manufacturing. Contamination by moisture due to handling operations is one of the most critical aspects of powder quality. In order to investigate the influences of powder humidity on LPBF processing, four materials (AlSi10Mg, Ti6Al4V, 316L and IN718) are chosen for this study. The powder material is artificially humidified, subsequently characterized, manufactured into cubic samples in a miniaturized process chamber and analyzed for their relative density. The results indicate that the processability and reproducibility of parts made of AlSi10Mg and Ti6Al4V are susceptible to humidity, while IN718 and 316L are barely influenced. KW - LPBF KW - Additive Manufacturing KW - Powder Material KW - Humidity Y1 - 2022 U6 - https://doi.org/10.1016/j.procir.2022.08.102 SN - 2212-8271 N1 - 12th CIRP Conference on Photonic Technologies [LANE 2022], 04. September 2022 bis 08. September 2022, Fürth VL - 111 SP - 115 EP - 120 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Eggert, Mathias A1 - Dyong, Julian T1 - Applying process mining in small and medium sized IT enterprises – challenges and guidelines T2 - Business Process Management, 20th International Conference, BPM 2022, Proceedings N2 - Process mining gets more and more attention even outside large enterprises and can be a major benefit for small and medium sized enterprises (SMEs) to gain competitive advantages. Applying process mining is challenging, particularly for SMEs because they have less resources and process maturity. So far, IS researchers analyzed process mining challenges with a focus on larger companies. This paper investigates the application of process mining by means of a case study and sheds light into the particular challenges of an IT SME. The results reveal 13 SME process mining challenges and seven guidelines to address them. In this way, the paper contributes to the understanding of process mining application in SME and shows similarities and differences to larger companies. KW - Process mining KW - Challenges KW - Guidelines KW - SME KW - Case Study Y1 - 2022 SN - 978-3-031-16103-2 U6 - https://doi.org/10.1007/978-3-031-16103-2_11 N1 - International Conference on Business Process Management (BPM 2022), Münster, Germany, Sept. 11-16, 2022 SP - 125 EP - 142 PB - Springer CY - Cham ER - TY - JOUR A1 - von Häfen, Hajo A1 - Krautwald, Clemens A1 - Stolle, Jacob A1 - Bung, Daniel Bernhard A1 - Goseberg, Nils T1 - Overland flow of broken solitary waves over a two-dimensional coastal plane JF - Coastal Engineering N2 - Landslides, rock falls or related subaerial and subaqueous mass slides can generate devastating impulse waves in adjacent waterbodies. Such waves can occur in lakes and fjords, or due to glacier calving in bays or at steep ocean coastlines. Infrastructure and residential houses along coastlines of those waterbodies are often situated on low elevation terrain, and are potentially at risk from inundation. Impulse waves, running up a uniform slope and generating an overland flow over an initially dry adjacent horizontal plane, represent a frequently found scenario, which needs to be better understood for disaster planning and mitigation. This study presents a novel set of large-scale flume test focusing on solitary waves propagating over a 1:14.5 slope and breaking onto a horizontal section. Examining the characteristics of overland flow, this study gives, for the first time, insight into the fundamental process of overland flow of a broken solitary wave: its shape and celerity, as well as its momentum when wave breaking has taken place beforehand. KW - Landslide tsunamis KW - Hazard assessment KW - Large scale tests KW - Overland flow KW - Solitary waves Y1 - 2022 U6 - https://doi.org/10.1016/j.coastaleng.2022.104125 SN - 1872-7379 VL - 175 IS - August PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Falkenberg, Fabian A1 - Rahba, Jade A1 - Fischer, David A1 - Bott, Michael A1 - Bongaerts, Johannes A1 - Siegert, Petra T1 - Biochemical characterization of a novel oxidatively stable, halotolerant, and high-alkaline subtilisin from Alkalihalobacillus okhensis Kh10-101T JF - FEBS Open Bio N2 - Halophilic and halotolerant microorganisms represent a promising source of salt-tolerant enzymes suitable for various biotechnological applications where high salt concentrations would otherwise limit enzymatic activity. Considering the current growing enzyme market and the need for more efficient and new biocatalysts, the present study aimed at the characterization of a high-alkaline subtilisin from Alkalihalobacillus okhensis Kh10-101T. The protease gene was cloned and expressed in Bacillus subtilis DB104. The recombinant protease SPAO with 269 amino acids belongs to the subfamily of high-alkaline subtilisins. The biochemical characteristics of purified SPAO were analyzed in comparison with subtilisin Carlsberg, Savinase, and BPN'. SPAO, a monomer with a molecular mass of 27.1 kDa, was active over a wide range of pH 6.0–12.0 and temperature 20–80 °C, optimally at pH 9.0–9.5 and 55 °C. The protease is highly oxidatively stable to hydrogen peroxide and retained 58% of residual activity when incubated at 10 °C with 5% (v/v) H2O2 for 1 h while stimulated at 1% (v/v) H2O2. Furthermore, SPAO was very stable and active at NaCl concentrations up to 5.0 m. This study demonstrates the potential of SPAO for biotechnological applications in the future. KW - Alkalihalobacillus okhensis KW - detergent protease KW - halotolerant protease KW - high-alkaline subtilisin KW - oxidative stable protease Y1 - 2022 U6 - https://doi.org/10.1002/2211-5463.13457 SN - 2211-5463 N1 - Corresponding author: Petra Siegert VL - 12 IS - 10 SP - 1729 EP - 1746 PB - Wiley CY - Hoboken, NJ ER - TY - JOUR A1 - Topçu, Murat A1 - Madabhushi, Gopal S.P. A1 - Staat, Manfred T1 - A generalized shear-lag theory for elastic stress transfer between matrix and fibres having a variable radius JF - International Journal of Solids and Structures N2 - A generalized shear-lag theory for fibres with variable radius is developed to analyse elastic fibre/matrix stress transfer. The theory accounts for the reinforcement of biological composites, such as soft tissue and bone tissue, as well as for the reinforcement of technical composite materials, such as fibre-reinforced polymers (FRP). The original shear-lag theory proposed by Cox in 1952 is generalized for fibres with variable radius and with symmetric and asymmetric ends. Analytical solutions are derived for the distribution of axial and interfacial shear stress in cylindrical and elliptical fibres, as well as conical and paraboloidal fibres with asymmetric ends. Additionally, the distribution of axial and interfacial shear stress for conical and paraboloidal fibres with symmetric ends are numerically predicted. The results are compared with solutions from axisymmetric finite element models. A parameter study is performed, to investigate the suitability of alternative fibre geometries for use in FRP. KW - Natural fibres KW - Polymer-matrix composites KW - Biocomposites KW - Stress concentrations KW - Finite element analysis Y1 - 2022 U6 - https://doi.org/10.1016/j.ijsolstr.2022.111464 SN - 0020-7683 VL - 239–240 IS - Art. No. 111464 PB - Elsevier CY - New York, NY ER - TY - JOUR A1 - Bhattarai, Aroj A1 - Horbach, Andreas A1 - Staat, Manfred A1 - Kowalczyk, Wojciech A1 - Tran, Thanh Ngoc T1 - Virgin passive colon biomechanics and a literature review of active contraction constitutive models JF - Biomechanics N2 - The objective of this paper is to present our findings on the biomechanical aspects of the virgin passive anisotropic hyperelasticity of the porcine colon based on equibiaxial tensile experiments. Firstly, the characterization of the intestine tissues is discussed for a nearly incompressible hyperelastic fiber-reinforced Holzapfel–Gasser–Ogden constitutive model in virgin passive loading conditions. The stability of the evaluated material parameters is checked for the polyconvexity of the adopted strain energy function using positive eigenvalue constraints of the Hessian matrix with MATLAB. The constitutive material description of the intestine with two collagen fibers in the submucosal and muscular layer each has been implemented in the FORTRAN platform of the commercial finite element software LS-DYNA, and two equibiaxial tensile simulations are presented to validate the results with the optical strain images obtained from the experiments. Furthermore, this paper also reviews the existing models of the active smooth muscle cells, but these models have not been computationally studied here. The review part shows that the constitutive models originally developed for the active contraction of skeletal muscle based on Hill’s three-element model, Murphy’s four-state cross-bridge chemical kinetic model and Huxley’s sliding-filament hypothesis, which are mainly used for arteries, are appropriate for numerical contraction numerical analysis of the large intestine. KW - virgin passive KW - strain energy function KW - smooth muscle contraction KW - viscoelasticity KW - damage Y1 - 2022 U6 - https://doi.org/10.3390/biomechanics2020013 SN - 2673-7078 VL - 2 IS - 2 SP - 138 EP - 157 PB - MDPI CY - Basel ER - TY - JOUR A1 - Golland, Alexander T1 - Aufsicht und Rechtsdurchsetzung bei unzulässigem Einsatz von Cookies & Co. unter Geltung des TTDSG JF - DSB Datenschutz-Berater KW - Informationstechnik KW - Rechtsgebiet KW - Datenschutz KW - Bundesrepublik Deutschland Y1 - 2022 SN - 0170-7256 VL - 46 IS - 1 SP - 14 EP - 16 PB - DFV Mediengruppe CY - Frankfurt a.M. ER - TY - CHAP A1 - Hoffschmidt, Bernhard A1 - Alexopoulos, Spiros A1 - Göttsche, Joachim A1 - Sauerborn, Markus A1 - Kaufhold, O. T1 - High Concentration Solar Collectors T2 - Comprehensive Renewable Energy (Second Edition) / Volume 3: Solar Thermal Systems: Components and Applications N2 - Solar thermal concentrated power is an emerging technology that provides clean electricity for the growing energy market. To the solar thermal concentrated power plant systems belong the parabolic trough, the Fresnel collector, the solar dish, and the central receiver system. For high-concentration solar collector systems, optical and thermal analysis is essential. There exist a number of measurement techniques and systems for the optical and thermal characterization of the efficiency of solar thermal concentrated systems. For each system, structure, components, and specific characteristics types are described. The chapter presents additionally an outline for the calculation of system performance and operation and maintenance topics. One main focus is set to the models of components and their construction details as well as different types on the market. In the later part of this article, different criteria for the choice of technology are analyzed in detail. KW - Central receiver system KW - Concentrated solar collector KW - Solar dish KW - Solar concentration Y1 - 2022 SN - 978-0-12-819734-9 U6 - https://doi.org/10.1016/B978-0-12-819727-1.00058-3 SP - 198 EP - 245 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Marinković, Marko A1 - Butenweg, Christoph ED - Ford, Michael C. T1 - Experimental testing of decoupled masonry infills with steel anchors for out-of-plane support under combined in-plane and out-of-plane seismic loading JF - Construction and Building Materials N2 - Because of simple construction process, high energy efficiency, significant fire resistance and excellent sound isolation, masonry infilled reinforced concrete (RC) frame structures are very popular in most of the countries in the world, as well as in seismic active areas. However, many RC frame structures with masonry infills were seriously damaged during earthquake events, as the traditional infills are generally constructed with direct contact to the RC frame which brings undesirable infill/frame interaction. This interaction leads to the activation of the equivalent diagonal strut in the infill panel, due to the RC frame deformation, and combined with seismically induced loads perpendicular to the infill panel often causes total collapses of the masonry infills and heavy damages to the RC frames. This fact was the motivation for developing different approaches for improving the behaviour of masonry infills, where infill isolation (decoupling) from the frame has been more intensively studied in the last decade. In-plane isolation of the infill wall reduces infill activation, but causes the need for additional measures to restrain out-of-plane movements. This can be provided by installing steel anchors, as proposed by some researchers. Within the framework of European research project INSYSME (Innovative Systems for Earthquake Resistant Masonry Enclosures in Reinforced Concrete Buildings) the system based on a use of elastomers for in-plane decoupling and steel anchors for out-of-plane restrain was tested. This constructive solution was tested and deeply investigated during the experimental campaign where traditional and decoupled masonry infilled RC frames with anchors were subjected to separate and combined in-plane ‬and out-of-plane loading. Based on a detailed evaluation and comparison of the test results, the performance and effectiveness of the developed system are illustrated. KW - Masonry infill KW - Reinforced concrete frame KW - Earthquake KW - INSYSME KW - Decoupling Y1 - 2022 U6 - https://doi.org/10.1016/j.conbuildmat.2021.126041 SN - 1879-0526 SN - 0950-0618 VL - 318 IS - 1 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tran, Ngoc Trinh A1 - Trinh, Tu Luc A1 - Dao, Ngoc Tien A1 - Giap, Van Tan A1 - Truong, Manh Khuyen A1 - Dinh, Thuy Ha A1 - Staat, Manfred T1 - FEM shakedown analysis of structures under random strength with chance constrained programming JF - Vietnam Journal of Mechanics N2 - Direct methods, comprising limit and shakedown analysis, are a branch of computational mechanics. They play a significant role in mechanical and civil engineering design. The concept of direct methods aims to determine the ultimate load carrying capacity of structures beyond the elastic range. In practical problems, the direct methods lead to nonlinear convex optimization problems with a large number of variables and constraints. If strength and loading are random quantities, the shakedown analysis can be formulated as stochastic programming problem. In this paper, a method called chance constrained programming is presented, which is an effective method of stochastic programming to solve shakedown analysis problems under random conditions of strength. In this study, the loading is deterministic, and the strength is a normally or lognormally distributed variable. KW - limit analysis KW - shakedown analysis KW - chance constrained programming KW - stochastic programming KW - reliability of structures Y1 - 2022 U6 - https://doi.org/10.15625/0866-7136/17943 SN - 0866-7136 SN - 2815-5882 VL - 44 IS - 4 SP - 459 EP - 473 PB - Vietnam Academy of Science and Technology (VAST) ER - TY - CHAP A1 - Hebel, Christoph A1 - Herrmann, Ulf A1 - Ritz, Thomas A1 - Röth, Thilo A1 - Anthrakidis, Anette A1 - Böker, Jörg A1 - Franzke, Till A1 - Grodzki, Thomas A1 - Merkens, Torsten A1 - Schöttler, Mirjam T1 - FlexSHARE – Methodisches Framework zur innovativen Gestaltung der urbanen Mobilität durch Sharing- Angebote T2 - Transforming Mobility – What Next? N2 - Das Ziel des INTERREG-Projektes „SHAREuregio“ (FKZ: 34.EFRE-0300134) ist es, grenzüberschreitende Mobilität in der Euregio Rhein-Maas-Nord zu ermöglichen und zu fördern. Dazu soll ein elektromobiles Car- und Bikesharing- System entwickelt und in der Stadt Mönchengladbach, im Kreis Viersen sowie in den Gemeinden Roermond und Venlo (beide NL) zusammen mit den Partnern Wirtschaftsförderung Mönchengladbach, Wirtschaftsförderung für den Kreis Viersen, NEW AG, Goodmoovs (NL), Greenflux (NL) und der FH Aachen implementiert werden. Zunächst richtet sich das Angebot, bestehend aus 40 Elektroautos und 40 Elektrofahrrädern, an Unternehmen und wird nach einer Erprobungsphase, mit einer größeren Anzahl an Fahrzeugen, auch für Privatpersonen verfügbar gemacht werden. Die Fahrzeuge stehen bei den jeweiligen Anwendungspartnern in Deutschland und den Niederlanden. Im Rahmen dieses Projektes hat die FH Aachen „FlexSHARE“ entwickelt – ein methodisches Framework zur innovativen Gestaltung urbaner Sharing- Angebote. Das Framework ermöglicht es, anhand von messbaren Kenngrößen, bedarfsgerechte und auf die Region abgestimmte Sharing-Systeme zu entwickeln. Y1 - 2022 SN - 978-3-658-36429-8 U6 - https://doi.org/10.1007/978-3-658-36430-4_10 N1 - Tagungsband zum 13. Wissenschaftsforum Mobilität, Beiträge des Wissenschaftsforums SP - 153 EP - 169 PB - Springer Gabler CY - Wiesbaden ER - TY - CHAP A1 - Welden, Melanie A1 - Severins, Robin A1 - Poghossian, Arshak A1 - Wege, Christina A1 - Siegert, Petra A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Studying the immobilization of acetoin reductase with Tobacco mosaic virus particles on capacitive field-effect sensors T2 - 2022 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN) N2 - A capacitive electrolyte-insulator-semiconductor (EISCAP) biosensor modified with Tobacco mosaic virus (TMV) particles for the detection of acetoin is presented. The enzyme acetoin reductase (AR) was immobilized on the surface of the EISCAP using TMV particles as nanoscaffolds. The study focused on the optimization of the TMV-assisted AR immobilization on the Ta 2 O 5 -gate EISCAP surface. The TMV-assisted acetoin EISCAPs were electrochemically characterized by means of leakage-current, capacitance-voltage, and constant-capacitance measurements. The TMV-modified transducer surface was studied via scanning electron microscopy. KW - Tobacco mosaic virus KW - acetoin KW - capacitive field-effect biosensor KW - enzyme immobilization Y1 - 2022 SN - 978-1-6654-5860-3 (Online) SN - 978-1-6654-5861-0 (Print) U6 - https://doi.org/10.1109/ISOEN54820.2022.9789657 N1 - IEEE International Symposium on Olfaction and Electronic Nose (ISOEN), 29 May 2022 - 01 June 2022, Aveiro, Portugal. PB - IEEE ER - TY - THES A1 - Wojcieszak, Marc David T1 - Da Capo - The Town of Music N2 - In dem Film geht es um die Musikstadt "Da Capo", in der jedes Genre sein eigenes Viertel hat. Unser Protagonist wurde im falschen Viertel geboren und muss sich nun heraus musizieren. KW - Musik KW - Film KW - Stadtviertel KW - Genre KW - musizieren Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - THES A1 - Wick, Dorian T1 - bulk : Konzeption und Gestaltung einer mobilen Anwendung eines nachhaltigen Unverpackt-Lieferservice N2 - Die Welt wird wortwörtlich von Plastik überschwemmt- und trotzdem ist kein Ende des trivialen Verpackungsmaterials in Sicht. Die, die sich den Konsequenzen ihres Konsumverhaltens bewusst sind, haben immer noch keinen flächendeckenden Zugang zu Unverpacktläden und es mangelt schlicht an praktischen Alternativen. Hier knüpft die App „bulk“ an und schlägt ausschließlich unverpackte Lebensmittel vor – bequem bis zur Haustür geliefert. Das Angebot ist qualitativ hochwertig und meist regional. Für ein positives Kauferlebnis veranschaulicht „bulk“, wie viel Plastik mit den Produkten im Vergleich zu einem konventionellen Wocheneinkauf eingespart werden kann. Das gibt Nutzer:Innen eine Grundlage, ihre Entscheidungen kritisch zu hinterfragen und schult den Blick für den Impact sich summierender Kleinigkeiten. KW - Plastik KW - App KW - Bulk KW - Konsumverhalten KW - Verpackungsmaterial Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Eberhardt, Dag Norman T1 - "I Was Here!" N2 - Die Menschheit erlebt aktuell Zeiten drastischen Wandels. Deswegen könnte es wohltun, einen Blick in die Vergangenheit zu werfen und sich darauf zu besinnen, wo die Menschen herkommen, wer sie waren und was seitdem bereits erreicht wurde. In dieser Grafiknovelle wird ein kleiner Steinzeitjunge namens Muami begleitet, der vor 35.000 Jahren die Vergänglichkeit des Lebens kennenlernt. Im Verlauf des folgenden Jahres erfindet er die Selbstverewigung in der Höhlenmalerei. Mit seiner Figur soll aufgezeigt werden, dass die frühen Europäer eben keine primitiven Halbaffen, sondern intelligente und außerdem zutiefst kreative Menschen waren. Trotz ihrer rauen Umwelt waren ihre Sorgen und Freuden den unseren gar nicht so unähnlich. „I Was Here!“ ist ein Versuch, ein authentisches Porträt jener Menschen zu schaffen und dabei ihrer Welt, ihrem Leben und ihrer Kunst gerecht zu werden. KW - Grafiknovelle KW - Comic KW - Steinzeit KW - Jungpaläolithikum KW - Höhlenmalerei Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Wolters, Marina T1 - Zeitfenster : Prototyp einer animierten Installation zum Thema Mesokosmos und Lebensraum Erde N2 - Der Prototyp des Projekts "Zeitfenster" stellt eine Installation dar, inspiriert vom Museum für Naturkunde Berlin. Die Installation besteht aus einer Animation, die an die Fenster des Dinosauriersaals im Museum pojiziert wird. Die Animation zeigt in einer Art Zeitreise, wie das Erbe der Natur aussieht und was der Mensch daraus macht. In der Zeit des Klimawandels setzt sich Design vermehrt für die Aufklärung des Naturschutzes ein. Die Animation soll die Zuschauer, ob Jung oder Alt, für die Verbindung zwischen dem Menschen und der Erde sensibilisieren. Dies wird erreicht, indem sich die Installation die atemberaubende Atmosphäre des Dinosauriersaals zu Nutze macht. Die Fenster des Saals erlauben es, die Bildnisse in beeindruckender Lebensgröße darzustellen. Im Fokus steht, dass der Prototyp ein Erlebnis konzipiert, welches nur durch das Zusammenspiel der verschiedenen Medien möglich ist. KW - Animation KW - Animationsfilm KW - Installation KW - Museum KW - Natur Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - THES A1 - Switalla, Justin T1 - Applause : Entwicklung eines Dokumentationssystems für die stationäre Altenpflege - Konzeption einer zukunftsgewandten Dokumentationslösung N2 - Der Personalmangel in der Pflege ist vor allem durch die Pandemie in den Fokus der Öffentlichkeit gerückt. Diese Situation wird sich in den nächsten Jahren aufgrund der steigenden Pflegequote in Folge des demografischen Wandels weiter zuspitzen. Das Dokumentieren der durchgeführten Tätigkeiten nimmt dabei viel Zeit in Anspruch, die nicht den Bewohner:innen zugutekommt. Das Dokumentationssystem „Applause“ soll Pflege- und Betreuungskräfte in ihrer Arbeit unterstützen und durch die einfache Nutzerführung den Schulungsaufwand reduzieren. Durch die Integration von modernen medizinischen Sensoren kann innerhalb des Systems der aktuelle Gesundheitsstatus der Bewohner:innen eingesehen werden. Zusätzlich wird die interne sowie externe Kommunikation innerhalb des Dokumentationssystems abgebildet. Bei Letzterer wird mittels einer datenschutzkonformen Software die auf Fax basierende Kommunikation abgelöst. KW - Pflegekräftemangel KW - Dokumentationssystem KW - Pflegekräfte KW - Gesundheit Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - JOUR A1 - Molinnus, Denise A1 - Iken, Heiko A1 - Johnen, Anna Lynn A1 - Richstein, Benjamin A1 - Hellmich, Lena A1 - Poghossian, Arshak A1 - Knoch, Joachim A1 - Schöning, Michael Josef T1 - Miniaturized pH-Sensitive Field-Effect Capacitors with Ultrathin Ta₂O₅ Films Prepared by Atomic Layer Deposition JF - physica status solidi (a) applications and materials science N2 - Miniaturized electrolyte–insulator–semiconductor capacitors (EISCAPs) with ultrathin gate insulators have been studied in terms of their pH-sensitive sensor characteristics: three different EISCAP systems consisting of Al–p-Si–Ta2O5(5 nm), Al–p-Si–Si3N4(1 or 2 nm)–Ta2O5 (5 nm), and Al–p-Si–SiO2(3.6 nm)–Ta2O5(5 nm) layer structures are characterized in buffer solution with different pH values by means of capacitance–voltage and constant capacitance method. The SiO2 and Si3N4 gate insulators are deposited by rapid thermal oxidation and rapid thermal nitridation, respectively, whereas the Ta2O5 film is prepared by atomic layer deposition. All EISCAP systems have a clear pH response, favoring the stacked gate insulators SiO2–Ta2O5 when considering the overall sensor characteristics, while the Si3N4(1 nm)–Ta2O5 stack delivers the largest accumulation capacitance (due to the lower equivalent oxide thickness) and a higher steepness in the slope of the capacitance–voltage curve among the studied stacked gate insulator systems. KW - atomic layer deposition KW - capacitive field-effect sensors KW - pH sensors KW - ultrathin gate insulators Y1 - 2022 U6 - https://doi.org/10.1002/pssa.202100660 SN - 1862-6319 N1 - Corresponding author: Michael J. Schöning VL - 219 IS - 8 PB - Wiley-VCH CY - Weinheim ER - TY - THES A1 - Leontieva, Ksenia Andreevna T1 - Die Facetten Hamburgs N2 - Im Rahmen dieser Masterarbeit entsteht ein neues Erscheinungsbild für die "Stiftung Historische Museen Hamburg". Dabei wurde ein medienübergreifendes Gestaltungskonzept entwickelt, welches dazu dienen soll, die Stiftung und deren musealen Einrichtungen modern, aussagekräftig und repräsentativ neu aufleben zu lassen, als auch das Interesse unserer Gesellschaft für Kunst, Kultur und Geschichte zu wecken und damit die Zielgruppe zu erweitern. Hierzu wurde das Corporate Design neu entwickelt, minimalisiert und modernisiert. Durch den aufgeräumten und organisierten digitalen Auftritt gelangen Interessenten schneller und gezielter zu Informationen über die Stiftung, die einzelnen Museen und deren Programm und Ausstellungen. Zusätzlich dienen als weiterführende Informationsquellen neu getslatete analoge Medien in Form von Plakaten, Flyern, Broschüren und Eintrittskarten. Weitestgehend wurde das Corporate Design in den urbanen Lebensraum der Stadt Hamburg integriert und neu interpretiert. Aus dem Gestaltungskonzept lässt sich ebenfalls ein neues Leitsystem zur besseren Orientierung in den Museen ableiten. Das Designkonzept zieht sich wie ein roter Faden durch alle Medien, um eine Einheit und einen Wiedererkennungswert zu schaffen und seriös und informativ zu wirken. Das Projekt ist rein fiktiv. KW - Informativ KW - Aufklärend KW - Historisch KW - Emotional KW - Wegweisend Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - THES A1 - Krebs, Benedikt T1 - Das Online-Ich : Erlebnis-Installation zur Reflexion über das digitale Selbst N2 - Soziale Netzwerke gehören zu den größten Konzernen der Welt. Hier werden minütlich Millionen von Nachrichten verschickt. Das Internet spielt eine stetig wachsende Rolle in der zwischenmenschlichen Kommunikation. Und doch funktioniert dort nicht nur die Sprache anders, auch die Persönlichkeit der Menschen kann sich auch verändern. Diese Arbeit beschäftigt sich mit dem „Online-Ich“, das jeder in sich tragen soll. Häufig ist dieses offener, hilfsbereiter und selbstloser, aber eben auch reizbarer, aggressiver und energetischer. Um auf diese Veränderung aufmerksam zu machen, werden die analoge und digitale Persönlichkeit verglichen. Dazu schöpft die Arbeit aus den vielfältigen Möglichkeiten von Virtual Reality, um Betrachtende in die Arbeit miteinzubeziehen. KW - Virtuelle Realität KW - Online KW - Enthemmung KW - Messestand KW - 3D Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - JOUR A1 - Heuermann, Holger A1 - Emmrich, Thomas A1 - Bongartz, Simon T1 - Microwave spark plug to support ignitions with high compression ratios JF - IEEE Transactions on Plasma Science N2 - Upcoming gasoline engines should run with a larger number of fuels beginning from petrol over methanol up to gas by a wide range of compression ratios and a homogeneous charge. In this article, the microwave (MW) spark plug, based on a high-speed frequency hopping system, is introduced as a solution, which can support a nitrogen compression ratio up to 1:39 in a chamber and more. First, an overview of the high-speed frequency hopping MW ignition and operation system as well as the large number of applications are presented. Both gives an understanding of this new base technology for MW plasma generation. Focus of the theoretical part is the explanation of the internal construction of the spark plug, on the achievable of the high voltage generation as well as the high efficiency to hold the plasma. In detail, the development process starting with circuit simulations and ending with the numerical multiphysics field simulations is described. The concept is evaluated with a reference prototype covering the frequency range between 2.40 and 2.48 GHz and working over a large power range from 20 to 200 W. A larger number of different measurements starting by vector hot-S11 measurements and ending by combined working scenarios out of hot temperature, high pressure and charge motion are winding up the article. The limits for the successful pressure tests were given by the pressure chamber. Pressures ranged from 1 to 39 bar and charge motion up to 25 m/s as well as temperatures from 30◦ to 125◦. KW - Automotive application KW - ignition KW - microplasma KW - microwave (MW) plasma KW - plasma jet Y1 - 2022 U6 - https://doi.org/10.1109/TPS.2022.3183690 SN - 1939-9375 IS - Early Access SP - 1 EP - 6 PB - IEEE ER - TY - THES A1 - Traut, Eva Melina T1 - Vom Öko-Dino zur Lifestyle-Marke : Rebranding für die Bio-Lebensmittelmarke Alnatura N2 - Das Thema „Bio“ ist auf dem Markt längst zu einem Mainstream geworden und vor allem bei jüngeren Zielgruppen sehr gefragt. Umso wichtiger ist es für Bio-Marken wie ALNATURA, sich zu definieren, um neben innovativen, nachhaltigen Start-up-Marken noch aufzufallen. Aktuell ist ALNATURA vorwiegend aufgrund der hochwertigen Produkte sowie einer transparenten Kommunikation bekannt. Jedoch fehlt es den Produkten an einheitlichem Design mit Wiedererkennungswert. Diese Arbeit zeigt einen Ansatz für ein neues, zeitgemäßes Gestaltungskonzept. Im Zuge dessen wurde das Unternehmenslogo modifiziert sowie Farben, Schrift und Gestaltungsraster neu definiert. Um das neue Image der Marke bekannt zu machen, wurde zudem eine Plakatkampagne entwickelt. Das Projekt zeigt, wie sich eine Bio-Marke weg vom Öko-Image und hin zu einer modernen Lifestyle-Marke mit Relevanz entwickeln kann. KW - Bio-Lebensmittelmarke KW - Alnatura KW - Transparenz KW - Corporate Design KW - Packaging Design Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Lebrecht, Rike-Charlotte T1 - Inga : ein modulares hydroponisches System für Endverbraucher N2 - In dieser Arbeit wurde sich mit der Frage auseinandergesetzt, wie sich der Nahrungsmittelanbau im urbanen Raum entwickeln könnte. Eine spannende Alternative zu traditionellen Anbaumethoden ist die Hydroponik, der Anbau von Pflanzen ohne Erde. Basierend auf dieser Technologie wurde in diesem Projekt ein Indoor-Garden-System gestaltet, welches den Nahrungsmittelanbau zurück zur Verbraucher:In bringt und zu einem bewussteren Umgang mit Lebensmitteln anregen soll. Denn mit „INGA“ kann frisches, pestizidfreies Blattgemüse ganz einfach zu Hause selbst angebaut werden. Das hydroponische System schafft mithilfe einer Nährstofflösung und künstlichem Licht optimale Wachstumsbedingungen für die Pflanzen – ganz unabhängig von örtlichen Gegebenheiten. Mithilfe seiner Modularität können Nutzer:Innen „INGA“ nach Belieben konfigurieren. Damit wird es einer breiten Zielgruppe mit unterschiedlichen Bedürfnissen gerecht und ermöglicht pestizidfreie Nahrung – auch in den Städten. KW - Urban KW - Hydroponik KW - Frisches Gemüse KW - Produktdesign KW - Industriedesign Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Lesmeister, David T1 - VIUR : urbanes Lagerfeuer N2 - Es kann ganze Lebensräume auslöschen, und doch wäre unsere Welt nicht die gleiche ohne Feuer. Feuer spielt eine wichtige Rolle in der menschlichen Evolution und diente unseren Vorfahren zum Schutz vor wilden Tieren, Kochen und zum Wärmen. Auch Gespräche am Lagerfeuer sollen einen erheblichen Einfluss auf die soziale und kulturelle Evolution des Menschen gehabt haben. Kein Wunder also, dass die Menschen bis heute mit Feuer ein Gefühl von Gemeinschaft und Geborgenheit verbinden. Genau diese Wirkung greift „VIUR“ auf und macht Feuer alltagstauglich für eine Welt, die von Urbanisierung und Digitalisierung geprägt ist. Entstanden ist ein Hybrid aus einem Tischfeuer und einem Grill. Somit entsteht sowohl das sinnliche Erlebnis einer Feuerstelle als auch die Möglichkeit, kleine Speisen zuzubereiten. Die smarte Konstruktion und ein Sicherheitsbrennstoff, mit dem sich kaum Rauch entwickeln kann, ermöglicht die Nutzung im kleinen Garten, aber eben auch auf einem Stadtbalkon. So kann das Lagerfeuer wieder seinen Zauber entfalten. KW - Lagerfeuer KW - Social Cocooning KW - Stress KW - Achtsamkeit KW - Flamme Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Nigge-Mans, Leonard T1 - Entwicklung einer Arbeitsplatzleuchte N2 - Für manche mag es banal wirken, doch für Gestalter:innen ist sie unverzichtbar: eine wirklich gute Leuchte für den Arbeitsplatz. Sie hat nämlich einen enormen Einfluss auf die Konzentration und den Komfort. Zudem ermöglicht gutes Licht erst ein sauberes und farbechtes Ergebnis. Dafür wurde in diesem Projekt die perfekte Leuchte entwickelt. Sie leuchtet die Arbeitsfläche ideal aus und unterstützt das Lesen, Schreiben oder die Arbeit mit technischen Geräten. Durch fünf Drehpunkte ist die Leuchte in alle Richtungen zu bewegen und lässt sich somit individuell auf ihre Aufgaben anpassen. Außerdem wurde Wert daraufgelegt, bestehende Normen und Vorschiften einzuhalten, um den Arbeit- und Gesundheitsschutz zu gewährleisten. Feierabend? Durch die Dim-Funktion wird die Arbeitsleuchte zu einer gemütlichen Lichtquelle. Unter anderem durch die unsichtbare Stromführung überzeugt die Lampe mit ihrer minimalistischen Designsprache und lässt sich in unterschiedlichste Räume integrieren. KW - Minimalistisch KW - Elegant KW - Auffällig KW - Multifunktional KW - Steuerbar Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Geilhausen, Ayleen T1 - SUE : Restauranterlebnisse neu gestalten N2 - Gastronomiebetriebe, insbesondere diese ohne zeitgemäße und durchdachte Konzepte wurden durch die Pandemie stark getroffen. Während große Fast-Food-Ketten bereits vor der Pandemie digitale Lösungen einsetzten, stehen nun auch andere Restaurantbetreiber:innen vor der Herausforderung der Digitalisierung. Gerade die Pandemie hat an dieser Stelle verdeutlicht, welche Restaurants ihre Prozesse im Sinne der User Experience durchdacht haben und welche nicht. Die Tisch-Stuhl-Kombination der „SUE“-Serie bietet Restaurants, smarte und elegante Gastronomiemöbel, die je nach Konzept in Materialität und Farbe frei anpassbar sind. Wandelbarkeit, Komfort und die Integration digitaler Lösungen sind die Kernkompetenzen und Anforderungen, die das Gastronomie-Interior in Zukunft erfüllen muss. Der smarte Bistrotisch und der wandelbare Stuhl der „SUE“-Serie zeigt einen digitalisierten und anpassbaren Lösungsansatz. KW - Restaurantmöbel KW - Gastronomie KW - Designstuhl KW - Restauranttisch KW - Produktdesign Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Braun, Linus T1 - Faces - Lebenswerte Mobilität in Städten N2 - Mobilität stellt oftmals ein Problem in Städten dar. Es sind Staus, Abgase, Platzmangel, die sich negativ auf die urbane Lebensqualität auswirken. Dies sind externe Auswirkungen der von Autos dominierten Mobilität. Ziel von „Faces“ war es, eine effiziente und vor allem attraktive Alternative zum Automobil zu bieten. Dafür denkt das Projekt die Straßenbahn neu. Durch kompaktes Design und die Verwendung autonomer Systeme wird eine höhere Taktung ermöglicht. Zudem werden die Bahnen flexibler und können den Einsatz am Mobilitätsbedarf anpassen. Um den Bedürfnissen der Fahrgäste gerecht zu werden, lässt sich das modulare Interior an die Reisedistanz anpassen. Hier wird ein Mobilitätskonzept gezeichnet, das einem mit einem hoffnungsvollen Blick auf das Leben in den Städten der Zukunft zurücklässt. KW - Mobilität KW - Zukunftsstädte KW - Urbanes Leben KW - Bahnen Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Bortmann, Alevtina T1 - Produktion eines „Corporate Identity“- Werbefilms für ein IoT Technologieunternehmen N2 - Mit einem Werbefilm kann man seine Zielgruppe schnell und einfach in wenigen Minuten erreichen, indem man sich als Unternehmen auf eine freundliche Art und Weise vorstellt und somit Vertrauen und Kontakt zu der Zielgruppe herstellt. Außerdem bietet ein Werbefilm eine gute Möglichkeit sein Unternehmen als modernes und leistungsstarkes Unternehmen zu präsentieren, um potenzielle Kunden oder sogar neue Mitarbeiter zu werben. Mit einem überzeugendem Werbefilm, der richtigen Musik und Animation, bleibt ein Werbefilm im Gedächtnis der Zuschauer, viel besser als es Printwerbung in Form von einem Flyer oder einer Broschüre erfüllen kann. Zusätzlich kann man seine Reichweite im Social-Media Bereich um weitere Kanäle erweitern. Dies wiederum ermöglicht dem Unternehmen seinen Kundenstamm zu stärken und auszubauen. KW - CI KW - Werbefilm KW - Video KW - Corporate Identity KW - IT Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - THES A1 - Voth, Emily T1 - KiWA : Die Garderobe für kleine Selbstständige N2 - Kindertagesstätten bieten Kleinkindern den Zugang zu unbeschwertem und spielerischem Lernen. Was also, wenn schon der Eingangsbereich die Reizüberflutung bereit hält, der Stauraum der Entfaltung der Kinder nicht gerecht wird und ihre Eigenständigkeit ungefördert bleibt? Es kommt zu unzufriedenen Kindern und Frustration aller Beteilligten. "KIWA" ist das Garderobensystem für Kinder zur Stärkung der heranwachsenden Selbstständigkeit. Mithilfe von persönlichen Wiedererkennungsmerkmalen wird Eigenverantwortung geschult. Leicht und sicher zu erreichender Stauraum sorgt für Ordnung. Spielerisches lernen trotz Ordnung. KW - Kindermöbel KW - Kindergarten KW - Möbeldesign KW - Ordnung KW - Kleinkinder Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - JOUR A1 - Monakhova, Yulia A1 - Diehl, Bernd W.K. T1 - Multinuclear NMR screening of pharmaceuticals using standardization by 2H integral of a deuterated solvent JF - Journal of Pharmaceutical and Biomedical Analysis N2 - NMR standardization approach that uses the 2H integral of deuterated solvent for quantitative multinuclear analysis of pharmaceuticals is described. As a proof of principle, the existing NMR procedure for the analysis of heparin products according to US Pharmacopeia monograph is extended to the determination of Na+ and Cl- content in this matrix. Quantification is performed based on the ratio of a 23Na (35Cl) NMR integral and 2H NMR signal of deuterated solvent, D2O, acquired using the specific spectrometer hardware. As an alternative, the possibility of 133Cs standardization using the addition of Cs2CO3 stock solution is shown. Validation characteristics (linearity, repeatability, sensitivity) are evaluated. A holistic NMR profiling of heparin products can now also be used for the quantitative determination of inorganic compounds in a single analytical run using a single sample. In general, the new standardization methodology provides an appealing alternative for the NMR screening of inorganic and organic components in pharmaceutical products. KW - NMR spectroscopy KW - Inorganic ions KW - Heparin KW - Standardization Y1 - 2022 SN - 0731-7085 U6 - https://doi.org/10.1016/j.jpba.2021.114530 VL - 209 IS - Article number: 114530 PB - Elsevier ER - TY - JOUR A1 - Molinnus, Denise A1 - Janus, Kevin Alexander A1 - Fang, Anyelina C. A1 - Drinic, Aleksander A1 - Achtsnicht, Stefan A1 - Köpf, Marius A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Thick-film carbon electrode deposited onto a biodegradable fibroin substrate for biosensing applications JF - Physica status solidi (a) N2 - This study addresses a proof-of-concept experiment with a biocompatible screen-printed carbon electrode deposited onto a biocompatible and biodegradable substrate, which is made of fibroin, a protein derived from silk of the Bombyx mori silkworm. To demonstrate the sensor performance, the carbon electrode is functionalized as a glucose biosensor with the enzyme glucose oxidase and encapsulated with a silicone rubber to ensure biocompatibility of the contact wires. The carbon electrode is fabricated by means of thick-film technology including a curing step to solidify the carbon paste. The influence of the curing temperature and curing time on the electrode morphology is analyzed via scanning electron microscopy. The electrochemical characterization of the glucose biosensor is performed by amperometric/voltammetric measurements of different glucose concentrations in phosphate buffer. Herein, systematic studies at applied potentials from 500 to 1200 mV to the carbon working electrode (vs the Ag/AgCl reference electrode) allow to determine the optimal working potential. Additionally, the influence of the curing parameters on the glucose sensitivity is examined over a time period of up to 361 days. The sensor shows a negligible cross-sensitivity toward ascorbic acid, noradrenaline, and adrenaline. The developed biocompatible biosensor is highly promising for future in vivo and epidermal applications. KW - biocompatible materials KW - biodegradable electronic devices KW - biosensors KW - carbon electrodes KW - glucose Y1 - 2022 U6 - https://doi.org/10.1002/pssa.202200100 SN - 1862-6319 N1 - Corresponding author: Michael J. Schöning VL - 219 IS - 23 SP - 1 EP - 9 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Engelmann, Ulrich M. A1 - Pourshahidi, Mohammad Ali A1 - Shalaby, Ahmed A1 - Krause, Hans-Joachim T1 - Probing particle size dependency of frequency mixing magnetic detection with dynamic relaxation simulation JF - Journal of Magnetism and Magnetic Materials N2 - Biomedical applications of magnetic nanoparticles (MNP) fundamentally rely on the particles’ magnetic relaxation as a response to an alternating magnetic field. The magnetic relaxation complexly depends on the interplay of MNP magnetic and physical properties with the applied field parameters. It is commonly accepted that particle core size is a major contributor to signal generation in all the above applications, however, most MNP samples comprise broad distribution spanning nm and more. Therefore, precise knowledge of the exact contribution of individual core sizes to signal generation is desired for optimal MNP design generally for each application. Specifically, we present a magnetic relaxation simulation-driven analysis of experimental frequency mixing magnetic detection (FMMD) for biosensing to quantify the contributions of individual core size fractions towards signal generation. Applying our method to two different experimental MNP systems, we found the most dominant contributions from approx. 20 nm sized particles in the two independent MNP systems. Additional comparison between freely suspended and immobilized MNP also reveals insight in the MNP microstructure, allowing to use FMMD for MNP characterization, as well as to further fine-tune its applicability in biosensing. Y1 - 2022 U6 - https://doi.org/10.1016/j.jmmm.2022.169965 SN - 0304-8853 VL - 563 IS - In progress, Art. No. 169965 PB - Elsevier CY - Amsterdam ER - TY - THES A1 - Büchel, Carolin T1 - GYMLET : dein mobiles Freiluftstudio - Entwicklung eines serientauglichen Prototypen und einer Vermarktungsstrategie N2 - Sportvereine verlieren zunehmend Mitglieder. Grund dafür ist der wachsende Wunsch nach unabhängigen Trainingsmöglichkeiten. GYMLET bietet den Sportler:innen die Möglichkeit, ihre Fitness funktional, selbstorganisiert und unabhängig zu trainieren. Dabei kann durch den selbstbestimmten Trainingsort neben der körperlichen Fitness vor allem die Motivation zur sportlichen Aktivität und das Wohlbefinden gesteigert werden. Unterstützt wird das Trainingssystem durch eine App, welche den Sportler:innen neben Nutzungsmöglichkeiten als Coach und Trainingsplaner dient. Um diese Trainingsmöglichkeit an die Zielgruppe heranzutragen, ist eine Kampagnenstrategie aus zwei Phasen entstanden. In dieser sollen Postings und Clips über Instagram und Youtube veröffentlicht werden. Zusätzlich werden Zeitschriften und mögliche Kooperationen mit Therapeuten oder Freizeitunterkünften zur Veröffentlichung der Kampagne genutzt. KW - Fitnesstraining KW - Kampagne KW - Outdoortraining KW - selbstorganisiertes Training KW - Freizeitsport Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - THES A1 - Victoria, Jacqueline T1 - IN BETWEEN : An attempt to capture emotions N2 - Emotionen durchlebt jeder Mensch. Von unserer Geburt bis zu unserem Tod. Der Psychologe Paul Eckman hat sechs grundlegende Emotionen identifiziert. Glück, Traurigkeit, Ekel, Angst, Überraschung und Wut. Emotionen können in positive und negative, aber auch in die weniger beachtete neutrale Emotion unterteilt werden. Emotionen werden ständig und wechselnd erlebt und sind deshalb vorstellbar als "Spektrum" oder als "Unendlichkeitschleife". Wie Menschen Emotionen erfahren, ist unterschiedlich. Sie sind abstrakt. Das Fotobuch "In Between" will das Emotionsspektrum und das Abstrakte mithilfe einer Kurzgeschichte sichtbar machen. Das Editorial und die fotografische Gestaltung greifen das Konzept der endlosen Schleife unserer Gefühlswelt auf und machen sie erlebbar. KW - Fotografie KW - Fotobuch KW - Emotion KW - Endlosschleife KW - Candid Fotografie Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - THES A1 - Frank, Jemima Leonie T1 - Falling in love with the female gaze N2 - Der „Male Gaze“ bezeichnet das typische Erleben der Umwelt aus männlicher Perspektive und prägt in den sogenannten Mainstream-Medien die Gestaltung von Film, Fernsehen und Werbung. Dadurch werden von dargestellten Personen häufig die körperlichen Aspekte hervorgehoben. Im Gegensatz dazu gilt das weibliche Pendant, der „Female Gaze“, als besonders emotionsbetont. Weil Medien einen enormen Einfluss auf gesellschaftliches und individuelles Denken haben, stellt die Dominanz des „Male Gaze“ eine Unausgeglichenheit dar, die sich in verschiedenen Bereichen des gesellschaftlichen Lebens widerspiegelt. Deswegen möchte dieses Projekt die Medien um die weibliche Sichtweise erweitern und damit die dort transportierten Bilder diverser und ausgewogener machen. Die Fotografie fokussiert sich dabei auf die Gefühlswelt der Protagonistin, womit die Betrachter:Innen schrittweise in ihre Position hineinversetzt werden sollen. Mit Augen des Mitgefühls und eigenem Schönheitsbegriff lässt „Falling in love with the female gaze“ endlich auch die Frau zu Wort kommen. KW - Weiblicher Blick KW - Fotografie KW - Emotional KW - Fühlen KW - Portrait Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - THES A1 - Rouenhoff, Saskia T1 - Blind – invisible connection : ein Spiel zur kritischen Auseinandersetzung mit den sozialen Medien. N2 - Im Computerspiel „blind – invisible connection“ taucht der Spieler in eine Fantasiewelt ein, die die sozialen Medien widerspiegelt und von einer Maschine beherrscht wird. Um zu erfahren, was in dieser Welt geschehen ist, muss die Geschichte Schritt für Schritt erspielt und wie ein Puzzle zusammengesetzt werden. Dabei interagieren die Spieler:innen mittels Dialogen mit den Bewohner:innen der Fantasiewelt und lösen Rätsel, die die Geschichte enthüllen. Durch Analogien zwischen der Fantasiewelt und den sozialen Medien wird die Funktionsweise und der Einfluss der Plattformen auf die Menschen und die Gesellschaft verdeutlicht. So wird eine Reflexion des eigenen Umgangs mit den sozialen Medien angeregt und Gesprächsstoff für Diskussionen unter den Spieler:innen und Mitmenschen geliefert. KW - Spiel KW - Computerspiel KW - App KW - Geschichte KW - Soziale Medien Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - THES A1 - Vasevska, Ivana T1 - FEEL IT_HEAL IT - the process of healing repressed emotions N2 - Unsere Emotionen beeinflussen die Art und Weise, wie wir mit uns selbst und der Welt um uns herum umgehen. Sie wirken sich auf unsere geistige und körperliche Gesundheit aus. Da einige unserer Emotionen als „schlecht“ oder „negativ“ wahrgenommen werden, erlauben wir uns oft nicht, sie zu fühlen, und wir unterdrücken sie. Ziel dieses Projekts ist es, mithilfe von Fotografie und Grafik zu zeigen, wie man mit unangenehmen und so genannten „negativen“ Emotionen umgehen kann. Der Schwerpunkt liegt gleichermaßen auf dem konzeptionellen und kreativen Teil. Dabei wurden ein Modell und wechselnde Farblichter verwendet, um die emotionalen Zustände einer Person darzustellen, die diese Transformation durchläuft. Ein weiteres Ziel ist es, die Bedeutung eines bewussteren Umgangs mit unseren Emotionen zu betonen. Das Endmedium ist ein Fotobuch inkl. Piktogramme, die die fünf Stadien repräsentieren: Leiden, Bewusstsein, Konfrontation, Ausdruck und Akzeptanz. (Suffering, Awareness, Confrontation, Expression and Acceptance). KW - Emotionen KW - Integration KW - Verdrängung KW - Heilung KW - Emotionaler Schmerz Y1 - 2022 PB - FH Aachen CY - Aachen ER - TY - THES A1 - Kocaoglu, Berna T1 - System zur Unterstützung von Blinden im Alltag N2 - Unterhaltungsgegenstände und ihre Add-Ons stellen für viele Menschen ein wichtiger Bestandteil eines ausgewogenen Lebens dar und sind somit nicht mehr aus klassischen Haushalten wegzudenken. Doch nicht jeder Menschen hat überhaupt Zugang zu ihnen, weil die Systeme meistens auf Durchschnittsbürger:Innen abgestimmt sind. Davon betroffen sind beispielsweise Menschen mit Blindheit und Seheinschränkung. Um das Angebot individueller zu gestalten, wurde diesem Projekt ein Home-Entertainment-System entwickelt, das eben genau auf die Bedürfnisse dieser Gruppe zugeschnitten ist. Für die bedienungsfreundliche Gestaltung wurde im gesamten Prozess besonders viel Wert auf die konkrete Lebensrealität von Blinden und Menschen mit Seheinschränkungen gelegt. Hier sollen mögliche Einschränkungen überwunden werden und sich möglichst den tatsächlichen Anforderungen in der Praxis anpassen. Dazu musste zunächst ein umfassendes Verständnis des Krankheitsbildes geschult werden. Außerdem wurde ein Blick in den Alltag dieser Menschen geworfen. Welche Home-Entertainmentgeräte finden bereits im Wohnzimmer Platz und welche Komplikationen gibt es mit ihnen? Die breite Palette an Produkten gibt einen Eindruck davon, welche Funktionen ersetzt und welche Systeme gegebenenfalls miteinander verknüpft werden können. Auf der Basis umfassender Recherche ist eine Fernbedienung entstanden, die sowohl per Sprachsteuerung als auch über physische Steuerung steuerbar ist. Zahlreiche taktile Elemente geben Orientierung bei der Nutzung und gewährleisten ein reibungsloses und handliches Nutzungserlebnis. Die Arbeit öffnet den Blick für andere Lebenswelten und plädiert für den Abbau von Barrieren für ein selbstbestimmteres Leben. KW - Unterhaltungsgegenstände KW - Blindheit KW - Seheinschränkung KW - Home-Entertainment-System KW - Sprachsteuerung Y1 - 2022 N1 - Für diese Arbeit steht kein Volltext zur Verfügung. PB - FH Aachen CY - Aachen ER - TY - JOUR A1 - Harris, Isaac A1 - Kleefeld, Andreas T1 - Analysis and computation of the transmission eigenvalues with a conductive boundary condition JF - Applicable Analysis N2 - We provide a new analytical and computational study of the transmission eigenvalues with a conductive boundary condition. These eigenvalues are derived from the scalar inverse scattering problem for an inhomogeneous material with a conductive boundary condition. The goal is to study how these eigenvalues depend on the material parameters in order to estimate the refractive index. The analytical questions we study are: deriving Faber–Krahn type lower bounds, the discreteness and limiting behavior of the transmission eigenvalues as the conductivity tends to infinity for a sign changing contrast. We also provide a numerical study of a new boundary integral equation for computing the eigenvalues. Lastly, using the limiting behavior we will numerically estimate the refractive index from the eigenvalues provided the conductivity is sufficiently large but unknown. KW - Boundary integral equations KW - Inverse spectral problem KW - Conductive boundary condition KW - Transmission eigenvalues Y1 - 2020 U6 - https://doi.org/10.1080/00036811.2020.1789598 SN - 1563-504X VL - 101 IS - 6 SP - 1880 EP - 1895 PB - Taylor & Francis CY - London ER - TY - CHAP A1 - Moorkamp, Wilfried A1 - Peterson, Leif Arne A1 - Uibel, Thomas ED - Fouad, Nabil A. T1 - Nachhaltige Holzbrücken für Geh- und Radwege T2 - Bauphysik Kalender 2022: Holzbau, 22. Jahrgang N2 - Am Lehr- und Forschungsgebiet Holzbau der Fachhochschule Aachen wurden im Rahmen des Forschungsvorhabens „Nachhaltige Standardbrücken in Holzbauweise“ Standardtypen für Geh- und Radwegbrücken entwickelt. Die Brücken sind durch konsequente Umsetzungen von Maßnahmen des konstruktiven Holzschutzes für eine Nutzung von mehr als 80~Jahren konzipiert. Innovative Lösungen für Bauteile und Anschlüsse sowie Materialalternativen im Bereich des Belages und der Geländer ermöglichen eine wartungsarme Konstruktion und tragen somit zur Wirtschaftlichkeit und Nachhaltigkeit bei. Um den Einsatz der entwickelten Standardbrückentypen in der Praxis zu erleichtern, wurden Leistungsverzeichnisse, Musterstatiken, Musterzeichnungen und umfangreiche Detailkataloge als Unterstützung für Planer und Bauherren erstellt. Damit die Randbedingungen für eine lange Lebensdauer während der Nutzung der Brücke erhalten bleiben, wurden Leitfäden für die Pflege und Wartung sowie für die Brückenprüfung erarbeitet. Der Beitrag gibt Einblicke in das Forschungsvorhaben und seine Resultate. Y1 - 2022 SN - 9783433033609 (Print) SN - 9783433611081 (Online) U6 - https://doi.org/10.1002/9783433611081.ch17 SP - 574 EP - 592 PB - Ernst & Sohn CY - Berlin ER - TY - JOUR A1 - Funke, Harald A1 - Esch, Thomas A1 - Roosen, Petra T1 - Antriebssystemanpassungen zur Verwendung von LPG als Flugkraftstoff JF - Motortechnische Zeitschrift (MTZ) N2 - Auch in der allgemeinen Luftfahrt wäre es wünschenswert, die bereits vorhandenen Verbrennungsmotoren mit weniger CO₂-trächtigen Kraftstoffen als dem heute weit verbreiteten Avgas 100LL betreiben zu können. Es ist anzunehmen, dass im Vergleich die unter Normalbedingungen gasförmigen Kraftstoffe CNG, LPG oder LNG deutlich weniger Emissionen produzieren. Erforderliche Antriebssystemanpassungen wurden im Rahmen eines Forschungsprojekts an der FH Aachen untersucht. Y1 - 2022 U6 - https://doi.org/10.1007/s35146-021-0778-2 VL - 2022 IS - 83 SP - 58 EP - 62 PB - Springer Nature CY - Basel ER - TY - JOUR A1 - Welden, Melanie A1 - Poghossian, Arshak A1 - Vahidpour, Farnoosh A1 - Wendlandt, Tim A1 - Keusgen, Michael A1 - Wege, Christina A1 - Schöning, Michael Josef T1 - Towards multi-analyte detection with field-effect capacitors modified with tobacco mosaic virus bioparticles as enzyme nanocarriers JF - Biosensors N2 - Utilizing an appropriate enzyme immobilization strategy is crucial for designing enzyme-based biosensors. Plant virus-like particles represent ideal nanoscaffolds for an extremely dense and precise immobilization of enzymes, due to their regular shape, high surface-to-volume ratio and high density of surface binding sites. In the present work, tobacco mosaic virus (TMV) particles were applied for the co-immobilization of penicillinase and urease onto the gate surface of a field-effect electrolyte-insulator-semiconductor capacitor (EISCAP) with a p-Si-SiO₂-Ta₂O₅ layer structure for the sequential detection of penicillin and urea. The TMV-assisted bi-enzyme EISCAP biosensor exhibited a high urea and penicillin sensitivity of 54 and 85 mV/dec, respectively, in the concentration range of 0.1–3 mM. For comparison, the characteristics of single-enzyme EISCAP biosensors modified with TMV particles immobilized with either penicillinase or urease were also investigated. The surface morphology of the TMV-modified Ta₂O₅-gate was analyzed by scanning electron microscopy. Additionally, the bi-enzyme EISCAP was applied to mimic an XOR (Exclusive OR) enzyme logic gate. KW - urease KW - enzyme-logic gate KW - bi-enzyme biosensor KW - capacitive field-effect sensor KW - tobacco mosaic virus (TMV) KW - penicillinase Y1 - 2022 U6 - https://doi.org/10.3390/bios12010043 SN - 2079-6374 N1 - This article belongs to the Special Issue "Biosensors: 10th Anniversary Feature Papers" VL - 12 IS - 1 PB - MDPI CY - Basel ER - TY - CHAP A1 - Schopen, Oliver A1 - Shabani, Bahman A1 - Esch, Thomas A1 - Kemper, Hans A1 - Shah, Neel ED - Rahim, S.A. ED - As'arry, A. ED - Zuhri, M.Y.M. ED - Harmin, M.Y. ED - Rezali, K.A.M. ED - Hairuddin, A.A. T1 - Quantitative evaluation of health management designs for fuel cell systems in transport vehicles T2 - 2nd UNITED-SAIG International Conference Proceedings N2 - Focusing on transport vehicles, mainly with regard to aviation applications, this paper presents compilation and subsequent quantitative evaluation of methods aimed at building an optimum integrated health management solution for fuel cell systems. The methods are divided into two different main types and compiled in a related scheme. Furthermore, different methods are analysed and evaluated based on parameters specific to the aviation context of this study. Finally, the most suitable method for use in fuel cell health management systems is identified and its performance and suitability is quantified. KW - aviation application KW - health management systems KW - fuel cell systems Y1 - 2022 N1 - 2nd UNITED-SAIG International Conference, 23-24 May 2022, Putrajaya, Malaysia SP - 1 EP - 3 ER - TY - JOUR A1 - Finkenberger, Isabel Maria T1 - Strukturwandel als transformative Wende JF - disP: The Planning Review Y1 - 2024 U6 - https://doi.org/10.1080/02513625.2022.2158603 SN - 0251-3625 VL - 58 IS - 3 SP - 86 EP - 94 PB - Taylor & Francis CY - Abingdon ER - TY - CHAP A1 - Fabo, Sabine T1 - Plüschviren – Zur Konstruktion von Nähe in Zeiten der Pandemie T2 - Interaktion – Emotion – Desinfektion ; Kunst und Museum in Zeiten von Corona / Birgit Richard, Jana Müller, Niklas von Reischach (Hrsg.) Y1 - 2022 SN - 978-3-593-51520-5 (Print) SN - 978-3-593-44960-9 (E-Book) SP - 45 EP - 69 PB - Campus CY - Frankfurt ; New York ER - TY - JOUR A1 - Kleefeld, Andreas A1 - Zimmermann, M. ED - Constanda, Christian ED - Bodmann, Bardo E.J. ED - Harris, Paul J. T1 - Computing Elastic Interior Transmission Eigenvalues JF - Integral Methods in Science and Engineering N2 - An alternative method is presented to numerically compute interior elastic transmission eigenvalues for various domains in two dimensions. This is achieved by discretizing the resulting system of boundary integral equations in combination with a nonlinear eigenvalue solver. Numerical results are given to show that this new approach can provide better results than the finite element method when dealing with general domains. Y1 - 2022 SN - 978-3-031-07171-3 U6 - https://doi.org/10.1007/978-3-031-07171-3_10 N1 - Corresponding author: Andreas Kleefeld SP - 139 EP - 155 PB - Birkhäuser CY - Cham ER - TY - JOUR A1 - Pourshahidi, Ali Mohammad A1 - Achtsnicht, Stefan A1 - Offenhäusser, Andreas A1 - Krause, Hans-Joachim ED - Offenhäusser, Andreas T1 - Frequency Mixing Magnetic Detection Setup Employing Permanent Ring Magnets as a Static Offset Field Source JF - Sensors N2 - Frequency mixing magnetic detection (FMMD) has been explored for its applications in fields of magnetic biosensing, multiplex detection of magnetic nanoparticles (MNP) and the determination of core size distribution of MNP samples. Such applications rely on the application of a static offset magnetic field, which is generated traditionally with an electromagnet. Such a setup requires a current source, as well as passive or active cooling strategies, which directly sets a limitation based on the portability aspect that is desired for point of care (POC) monitoring applications. In this work, a measurement head is introduced that involves the utilization of two ring-shaped permanent magnets to generate a static offset magnetic field. A steel cylinder in the ring bores homogenizes the field. By variation of the distance between the ring magnets and of the thickness of the steel cylinder, the magnitude of the magnetic field at the sample position can be adjusted. Furthermore, the measurement setup is compared to the electromagnet offset module based on measured signals and temperature behavior. KW - magnetic sensors KW - biosensors KW - frequency mixing magnetic detection KW - magnetic nanoparticles Y1 - 2022 U6 - https://doi.org/10.3390/s22228776 SN - 1424-8220 VL - 22 IS - 22 PB - MDPI CY - Basel ER - TY - BOOK A1 - Laack, Walter van T1 - Schnittstelle Tod: Was lernen wir durch Corona über Leben und Tod? Y1 - 2022 SN - 978-3-936624-53-3 N1 - Siebter Tagungsband aus der Buchreihe “Schnittstelle Tod” PB - van Laack GmbH CY - Aachen ER - TY - JOUR A1 - Röthenbacher, Annika A1 - Cesari, Matteo A1 - Doppler, Christopher E.J. A1 - Okkels, Niels A1 - Willemsen, Nele A1 - Sembowski, Nora A1 - Seger, Aline A1 - Lindner, Marie A1 - Brune, Corinna A1 - Stefani, Ambra A1 - Högl, Birgit A1 - Bialonski, Stephan A1 - Borghammer, Per A1 - Fink, Gereon R. A1 - Schober, Martin A1 - Sommerauer, Michael T1 - RBDtector: an open-source software to detect REM sleep without atonia according to visual scoring criteria JF - Scientific Reports N2 - REM sleep without atonia (RSWA) is a key feature for the diagnosis of rapid eye movement (REM) sleep behaviour disorder (RBD). We introduce RBDtector, a novel open-source software to score RSWA according to established SINBAR visual scoring criteria. We assessed muscle activity of the mentalis, flexor digitorum superficialis (FDS), and anterior tibialis (AT) muscles. RSWA was scored manually as tonic, phasic, and any activity by human scorers as well as using RBDtector in 20 subjects. Subsequently, 174 subjects (72 without RBD and 102 with RBD) were analysed with RBDtector to show the algorithm’s applicability. We additionally compared RBDtector estimates to a previously published dataset. RBDtector showed robust conformity with human scorings. The highest congruency was achieved for phasic and any activity of the FDS. Combining mentalis any and FDS any, RBDtector identified RBD subjects with 100% specificity and 96% sensitivity applying a cut-off of 20.6%. Comparable performance was obtained without manual artefact removal. RBD subjects also showed muscle bouts of higher amplitude and longer duration. RBDtector provides estimates of tonic, phasic, and any activity comparable to human scorings. RBDtector, which is freely available, can help identify RBD subjects and provides reliable RSWA metrics. Y1 - 2022 U6 - https://doi.org/10.1038/s41598-022-25163-9 SN - 2045-2322 VL - 12 IS - Article number: 20886 SP - 1 EP - 14 PB - Springer Nature CY - London ER - TY - JOUR A1 - Falkenberg, Fabian A1 - Bott, Michael A1 - Bongaerts, Johannes A1 - Siegert, Petra T1 - Phylogenetic survey of the subtilase family and a data-mining-based search for new subtilisins from Bacillaceae JF - Frontiers in Microbiology N2 - The subtilase family (S8), a member of the clan SB of serine proteases are ubiquitous in all kingdoms of life and fulfil different physiological functions. Subtilases are divided in several groups and especially subtilisins are of interest as they are used in various industrial sectors. Therefore, we searched for new subtilisin sequences of the family Bacillaceae using a data mining approach. The obtained 1,400 sequences were phylogenetically classified in the context of the subtilase family. This required an updated comprehensive overview of the different groups within this family. To fill this gap, we conducted a phylogenetic survey of the S8 family with characterised holotypes derived from the MEROPS database. The analysis revealed the presence of eight previously uncharacterised groups and 13 subgroups within the S8 family. The sequences that emerged from the data mining with the set filter parameters were mainly assigned to the subtilisin subgroups of true subtilisins, high-alkaline subtilisins, and phylogenetically intermediate subtilisins and represent an excellent source for new subtilisin candidates. Y1 - 2022 U6 - https://doi.org/10.3389/fmicb.2022.1017978 SN - 1664-302X VL - 2022 IS - 13 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Welden, Melanie A1 - Severins, Robin A1 - Poghossian, Arshak A1 - Wege, Christina A1 - Bongaerts, Johannes A1 - Siegert, Petra A1 - Keusgen, Michael A1 - Schöning, Michael Josef T1 - Detection of acetoin and diacetyl by a tobacco mosaic virus-assisted field-effect biosensor JF - Chemosensors N2 - Acetoin and diacetyl have a major impact on the flavor of alcoholic beverages such as wine or beer. Therefore, their measurement is important during the fermentation process. Until now, gas chromatographic techniques have typically been applied; however, these require expensive laboratory equipment and trained staff, and do not allow for online monitoring. In this work, a capacitive electrolyte–insulator–semiconductor sensor modified with tobacco mosaic virus (TMV) particles as enzyme nanocarriers for the detection of acetoin and diacetyl is presented. The enzyme acetoin reductase from Alkalihalobacillus clausii DSM 8716ᵀ is immobilized via biotin–streptavidin affinity, binding to the surface of the TMV particles. The TMV-assisted biosensor is electrochemically characterized by means of leakage–current, capacitance–voltage, and constant capacitance measurements. In this paper, the novel biosensor is studied regarding its sensitivity and long-term stability in buffer solution. Moreover, the TMV-assisted capacitive field-effect sensor is applied for the detection of diacetyl for the first time. The measurement of acetoin and diacetyl with the same sensor setup is demonstrated. Finally, the successive detection of acetoin and diacetyl in buffer and in diluted beer is studied by tuning the sensitivity of the biosensor using the pH value of the measurement solution. Y1 - 2022 U6 - https://doi.org/10.3390/chemosensors10060218 SN - 2227-9040 N1 - This article belongs to the Special Issue "Nanostructured Devices for Biochemical Sensing" VL - 10 IS - 6 PB - MDPI CY - Basel ER - TY - JOUR A1 - Uysal, Karya A1 - Firat, Ipek Serat A1 - Creutz, Till A1 - Aydin, Inci Cansu A1 - Artmann, Gerhard A1 - Teusch, Nicole A1 - Temiz Artmann, Aysegül T1 - A novel in vitro wound healing assay using free-standing, ultra-thin PDMS membranes JF - membranes N2 - Advances in polymer science have significantly increased polymer applications in life sciences. We report the use of free-standing, ultra-thin polydimethylsiloxane (PDMS) membranes, called CellDrum, as cell culture substrates for an in vitro wound model. Dermal fibroblast monolayers from 28- and 88-year-old donors were cultured on CellDrums. By using stainless steel balls, circular cell-free areas were created in the cell layer (wounding). Sinusoidal strain of 1 Hz, 5% strain, was applied to membranes for 30 min in 4 sessions. The gap circumference and closure rate of un-stretched samples (controls) and stretched samples were monitored over 4 days to investigate the effects of donor age and mechanical strain on wound closure. A significant decrease in gap circumference and an increase in gap closure rate were observed in trained samples from younger donors and control samples from older donors. In contrast, a significant decrease in gap closure rate and an increase in wound circumference were observed in the trained samples from older donors. Through these results, we propose the model of a cell monolayer on stretchable CellDrums as a practical tool for wound healing research. The combination of biomechanical cell loading in conjunction with analyses such as gene/protein expression seems promising beyond the scope published here. Y1 - 2022 U6 - https://doi.org/10.3390/membranes13010022 N1 - This article belongs to the Special Issue "Latest Scientific Discoveries in Polymer Membranes" VL - 2023 IS - 13(1) PB - MDPI CY - Basel ER - TY - JOUR A1 - Ojovan, Michael I. A1 - Steinmetz, Hans-Jürgen T1 - Approaches to Disposal of Nuclear Waste JF - Energies N2 - We present a concise mini overview on the approaches to the disposal of nuclear waste currently used or deployed. The disposal of nuclear waste is the end point of nuclear waste management (NWM) activities and is the emplacement of waste in an appropriate facility without the intention to retrieve it. The IAEA has developed an internationally accepted classification scheme based on the end points of NWM, which is used as guidance. Retention times needed for safe isolation of waste radionuclides are estimated based on the radiotoxicity of nuclear waste. Disposal facilities usually rely on a multi-barrier defence system to isolate the waste from the biosphere, which comprises the natural geological barrier and the engineered barrier system. Disposal facilities could be of a trench type, vaults, tunnels, shafts, boreholes, or mined repositories. A graded approach relates the depth of the disposal facilities’ location with the level of hazard. Disposal practices demonstrate the reliability of nuclear waste disposal with minimal expected impacts on the environment and humans. KW - borehole disposal KW - geological disposal KW - disposal facility KW - retention time KW - nuclear waste Y1 - 2022 U6 - https://doi.org/10.3390/en15207804 SN - 1996-1073 N1 - This article belongs to the Special Issue "Treatment of Radioactive Waste and Sustainability Energy" VL - 15 IS - 20 PB - MDPI CY - Basel ER - TY - GEN A1 - Braun, Lena A1 - Krafft, Simone A1 - Tippkötter, Nils T1 - Combined supercritical carbon dioxide extraction and chromatography of the algae fatty linoleic and linolenic acid T2 - Chemie Ingenieur Technik N2 - A method for the integrated extraction and separation of fatty acids from algae using supercritical CO2 is presented. Desmodesmus obliquus and Chlorella sorokiniana were used as algae. First, a method for chromatographic separation of fatty acids of different degrees of saturation was established and optimized. Then, an integrated method for supercritical extraction was developed for both algal species. It was also verified whether prior cell disruption was beneficial for extraction. In developing the method for chromatographic separation, statistical experimental design was used to determine the optimal parameter settings. The methanol content in the mobile phase proved to be the most important parameter for successful separation of the three unsaturated fatty acids oleic acid, linoleic acid, and linolenic acid. Supercritical extraction with dried algae showed that about four times more fatty acids can be extracted from C. sorokiniana relative to the dry mass used. Y1 - 2022 U6 - https://doi.org/10.1002/cite.202255308 SN - 0009-286X SN - 1522-2640 (eISSN) N1 - ProcessNet and DECHEMA‐BioTechNet Jahrestagungen 2022 together with 13th ESBES Symposium 2022, 12. - 15. September 2022, Eurogress Aachen VL - 94 IS - 9 SP - 1304 PB - Wiley-VCH CY - Weinheim ER - TY - BOOK A1 - Laack, Walter van T1 - Aufruf zum Nachdenken: Corona und neue Kriege – Wie kann die Menschheit überleben? T1 - Call for Reflection: Corona and New Wars – How can Mankind survive? Y1 - 2022 SN - 978-3-936624-56-4 N1 - Dritter Band der Buchreihe “Vorträge & Einsichten – Lectures & Insights” und hier das zweite “Upside-Down-Buch”: Deutsche und englische Version in einem Buch. PB - van Laack GmbH CY - Aachen ER - TY - GEN A1 - Wiegner, J. A1 - Volker, H. A1 - Mainz, F. A1 - Backes, A. A1 - Löken, M. A1 - Hüning, Felix T1 - Wiegand-Effect-Powered Wireless IT Sensor Node N2 - With the growing interest in small distributed sensors for the “Internet of Things”, more attention is being paid to energy harvesting techologies. Reducing or eliminating the need for external power sources or batteries make devices more self-sufficient, more reliable, and reduces maintenance requirements. The Wiegand effect is a proven technology for harvesting small amounts of electrical power from mechanical motion. Y1 - 2022 N1 - PSMA International Energy Harvesting Workshop ~ 5-7 April 2022, Raleigh, NC, USA ER - TY - GEN A1 - Feldmann, Marco A1 - Francke, Gero A1 - Espe, Clemes A1 - Chen, Qian A1 - Baader, Fabian A1 - Boxberg, Marc S. A1 - Sustrate, Anna-Marie A1 - Kowalski, Julia A1 - Dachwald, Bernd T1 - Performance data of an ice-melting probe from field tests in two different ice environments N2 - This dataset was acquired at field tests of the steerable ice-melting probe "EnEx-IceMole" (Dachwald et al., 2014). A field test in summer 2014 was used to test the melting probe's system, before the probe was shipped to Antarctica, where, in international cooperation with the MIDGE project, the objective of a sampling mission in the southern hemisphere summer 2014/2015 was to return a clean englacial sample from the subglacial brine reservoir supplying the Blood Falls at Taylor Glacier (Badgeley et al., 2017, German et al., 2021). The standardized log-files generated by the IceMole during melting operation include more than 100 operational parameters, housekeeping information, and error states, which are reported to the base station in intervals of 4 s. Occasional packet loss in data transmission resulted in a sparse number of increased sampling intervals, which where compensated for by linear interpolation during post processing. The presented dataset is based on a subset of this data: The penetration distance is calculated based on the ice screw drive encoder signal, providing the rate of rotation, and the screw's thread pitch. The melting speed is calculated from the same data, assuming the rate of rotation to be constant over one sampling interval. The contact force is calculated from the longitudinal screw force, which es measured by strain gauges. The used heating power is calculated from binary states of all heating elements, which can only be either switched on or off. Temperatures are measured at each heating element and averaged for three zones (melting head, side-wall heaters and back-plate heaters). KW - Ocean Worlds KW - Icy Moons KW - Cryobot KW - Analogue Environments KW - Melting Efficiency KW - Melting Performance KW - Melting Probe KW - Ice Melting Y1 - 2022 U6 - https://doi.org/10.5281/zenodo.6094866 N1 - Forschungsdaten zu "Field-test performance of an ice-melting probe in a terrestrial analogue environment" (https://opus.bibliothek.fh-aachen.de/opus4/frontdoor/index/index/docId/10889) ER - TY - CHAP A1 - Mayntz, Joscha A1 - Keimer, Jona A1 - Dahmann, Peter A1 - Hille, Sebastian A1 - Stumpf, Eike A1 - Fisher, Alex A1 - Dorrington, Graham T1 - Electrical Drive and Regeneration in General Aviation Flight with Propellers T2 - Deutscher Luft- und Raumfahrtkongress 2020 N2 - Electric flight has the potential for a more sustainable and energy-saving way of aviation compared to fossil fuel aviation. The electric motor can be used as a generator inflight to regenerate energy during descent. Three different approaches to regenerating with electric propeller powertrains are proposed in this paper. The powertrain is to be set up in a wind tunnel to determine the propeller efficiency in both working modes as well as the noise emissions. Furthermore, the planned flight tests are discussed. In preparation for these tests, a yaw stability analysis is performed with the result that the aeroplane is controllable during flight and in the most critical failure case. The paper shows the potential for inflight regeneration and addresses the research gaps in the dual role of electric powertrains for propulsion and regeneration of general aviation aircraft. KW - Propeller Aerodynamics KW - Flight Tests KW - Flight Mechanics KW - Electrical Flight KW - Inflight Regeneration, Recuperation Y1 - 2022 U6 - https://doi.org/10.25967/530100 N1 - Deutscher Luft- und Raumfahrtkongress 2020, 1. - 3. September 2020, Online PB - DGLR CY - Bonn ER - TY - CHAP A1 - Losse, Ann-Kathrin A1 - Gehrke, Melanie A1 - Ullrich, André A1 - Czarnecki, Christian A1 - Sultanow, Eldar A1 - Breithaupt, Carsten A1 - Koch, Christian T1 - Entwicklung einer Open-Data-Referenzarchitektur für die Luftfahrtindustrie T2 - INFORMATIK 2022 - Informatik in den Naturwissenschaften, Proceedings N2 - Open Data impliziert die freie Zugänglichkeit, Verfügbarkeit und Wiederverwendbarkeit von Datensätzen. Obwohl hochwertige Datensätze öffentlich verfügbar sind, ist der Zugang zu diesen und die Transparenz über die Formate nicht immer gegeben. Dies mindert die optimale Nutzung des Potenzials zur Wertschöpfung, trotz der vorherrschenden Einigkeit über ihre Chancen. Denn Open Data ermöglicht das Vorantreiben von Compliance-Themen wie Transparenz und Rechenschaftspflicht bis hin zur Förderung von Innovationen. Die Nutzung von Open Data erfordert Mut und eine gemeinsame Anstrengung verschiedener Akteure und Branchen. Im Rahmen des vorliegenden Beitrags werden auf Grundlage des Design Science-Ansatzes eine Open Data Capability Map sowie darauf aufbauend eine Datenarchitektur für Open Data in der Luftfahrtindustrie an einem Beispiel entwickelt. Y1 - 2022 SN - 978-3-88579-720-3 U6 - https://doi.org/10.18420/inf2022_103 SN - 1617-5468 N1 - INFORMATIK 2022, 26. - 30. September 2022, Hamburg SP - 1203 EP - 1209 PB - GI - Gesellschaft für Informatik CY - Bonn ER - TY - JOUR A1 - Finkenberger, Isabel Maria T1 - Transformatives Forschen, Lehren und Handeln im Rheinischen Braunkohlerevier JF - Forum Wohnen und Stadtentwicklung N2 - Die Institution Hochschule hat das Potenzial, über transformatives Forschen und Lehren und den entsprechenden Wissenstransfer in den lokalen Kontext strategisch-verlässliche Partnerin der Großen Transformation zur Nachhaltigkeit zu werden und bei der Ausbildung von Pionierinnen und Pionieren des Wandels mitzuwirken. Der Lehr- und Forschungsschwerpunkt „Zukunftsfähige Transformation” am Fachbereich Architektur der FH Aachen widmet sich seit 2020 dem Tagebauumfeld Hambach im Rheinischen Revier, um dort angewandt und in Kooperation neue Narrative, innovative Prozesse, ortsbezogene Konzepte und strategische Projekte zu entwickeln und umzusetzen. Y1 - 2024 SN - 1439-7242 VL - 2022 IS - 2 SP - 69 EP - 72 PB - vhw CY - Berlin ER - TY - CHAP A1 - Fabo, Sabine T1 - Pandemische Momente T2 - Interaktion – Emotion – Desinfektion ; Kunst und Museum in Zeiten von Corona / Birgit Richard, Jana Müller, Niklas von Reischach (Hrsg.) Y1 - 2022 SN - 978-3-593-51520-5 (Print) SN - 978-3-593-44960-9 (E-Book) SP - 137 EP - 140 PB - Campus CY - Frankfurt ; New York ER - TY - JOUR A1 - Penner, Crystal A1 - Usherovich, Samuel A1 - Niedermeier, Jana A1 - Bélanger-Champagne, Camille A1 - Trinczek, Michael A1 - Paulßen, Elisabeth A1 - Hoehr, Cornelia T1 - Organic Scintillator-Fibre Sensors for Proton Therapy Dosimetry: SCSF-3HF and EJ-260 JF - electronics N2 - In proton therapy, the dose from secondary neutrons to the patient can contribute to side effects and the creation of secondary cancer. A simple and fast detection system to distinguish between dose from protons and neutrons both in pretreatment verification as well as potentially in vivo monitoring is needed to minimize dose from secondary neutrons. Two 3 mm long, 1 mm diameter organic scintillators were tested for candidacy to be used in a proton–neutron discrimination detector. The SCSF-3HF (1500) scintillating fibre (Kuraray Co. Chiyoda-ku, Tokyo, Japan) and EJ-260 plastic scintillator (Eljen Technology, Sweetwater, TX, USA) were irradiated at the TRIUMF Neutron Facility and the Proton Therapy Research Centre. In the proton beam, we compared the raw Bragg peak and spread-out Bragg peak response to the industry standard Markus chamber detector. Both scintillator sensors exhibited quenching at high LET in the Bragg peak, presenting a peak-to-entrance ratio of 2.59 for the EJ-260 and 2.63 for the SCSF-3HF fibre, compared to 3.70 for the Markus chamber. The SCSF-3HF sensor demonstrated 1.3 times the sensitivity to protons and 3 times the sensitivity to neutrons as compared to the EJ-260 sensor. Combined with our equations relating neutron and proton contributions to dose during proton irradiations, and the application of Birks’ quenching correction, these fibres provide valid candidates for inexpensive and replicable proton-neutron discrimination detectors Y1 - 2022 U6 - https://doi.org/10.3390/electronics12010011 SN - 2079-9292 N1 - This article belongs to the Special Issue "Applications of Optical Fiber Sensors" VL - 12 IS - 1 PB - MDPI CY - Basel ER - TY - JOUR A1 - Vahidpour, Farnoosh A1 - Guthman, Eric A1 - Arreola, Julia A1 - Alghazali, Yousef H. M. A1 - Wagner, Torsten A1 - Schöning, Michael Josef T1 - Assessment of Various Process Parameters for Optimized Sterilization Conditions Using a Multi-Sensing Platform JF - Foods N2 - In this study, an online multi-sensing platform was engineered to simultaneously evaluate various process parameters of food package sterilization using gaseous hydrogen peroxide (H₂O₂). The platform enabled the validation of critical aseptic parameters. In parallel, one series of microbiological count reduction tests was performed using highly resistant spores of B. atrophaeus DSM 675 to act as the reference method for sterility validation. By means of the multi-sensing platform together with microbiological tests, we examined sterilization process parameters to define the most effective conditions with regards to the highest spore kill rate necessary for aseptic packaging. As these parameters are mutually associated, a correlation between different factors was elaborated. The resulting correlation indicated the need for specific conditions regarding the applied H₂O₂ gas temperature, the gas flow and concentration, the relative humidity and the exposure time. Finally, the novel multi-sensing platform together with the mobile electronic readout setup allowed for the online and on-site monitoring of the sterilization process, selecting the best conditions for sterility and, at the same time, reducing the use of the time-consuming and costly microbiological tests that are currently used in the food package industry. KW - spore kill rate KW - sterility KW - aseptic parameters KW - multi-sensing platform KW - gaseous hydrogen peroxide Y1 - 2022 U6 - https://doi.org/10.3390/foods11050660 SN - 2304-8158 N1 - This article belongs to the Special Issue "Sensors and Biosensors Application for Food Industries" VL - 11 IS - 5 PB - MDPI CY - Basel ER - TY - JOUR A1 - Poghossian, Arshak A1 - Karschuck, Tobias A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Field-Effect Capacitors Decorated with Ligand-Stabilized Gold Nanoparticles: Modeling and Experiments JF - Biosensors N2 - Nanoparticles are recognized as highly attractive tunable materials for designing field-effect biosensors with enhanced performance. In this work, we present a theoretical model for electrolyte-insulator-semiconductor capacitors (EISCAP) decorated with ligand-stabilized charged gold nanoparticles. The charged AuNPs are taken into account as additional, nanometer-sized local gates. The capacitance-voltage (C–V) curves and constant-capacitance (ConCap) signals of the AuNP-decorated EISCAPs have been simulated. The impact of the AuNP coverage on the shift of the C–V curves and the ConCap signals was also studied experimentally on Al–p-Si–SiO₂ EISCAPs decorated with positively charged aminooctanethiol-capped AuNPs. In addition, the surface of the EISCAPs, modified with AuNPs, was characterized by scanning electron microscopy for different immobilization times of the nanoparticles. KW - aminooctanethiol KW - nanoparticle coverage KW - capacitive model KW - gold nanoparticles KW - field-effect sensor KW - electrolyte-insulator-semiconductor capacitors Y1 - 2022 U6 - https://doi.org/10.3390/bios12050334 SN - 2079-6374 N1 - This article belongs to the Special Issue "Biosensors in Nanotechnology" VL - 12 IS - 5 PB - MDPI CY - Basel ER - TY - CHAP A1 - Golland, Alexander ED - Riechert, Anne ED - Wilmer, Thomas T1 - Kommentierung von § 26 Telekommunikation-Telemedien-Datenschutzgesetz T2 - TTDSG Y1 - 2022 SN - 978-3-503-20978-1 N1 - Gedruckte Ausgabe unter 21 QRUG 2 verfügbar. SP - 439 EP - 474 PB - Erich Schmidt CY - Berlin ER - TY - CHAP A1 - Kurz, Melanie T1 - Vom Werkbundstreit bis zur Papierformatnormung - welche Rolle der Chemie-Nobelpreisträger Friedrich Wilhelm Ostwald bei Typisierungsbestrebungen im Design spielt T2 - Raster, Regeln, Ratio : Systematiken und Normungen des 20. Jahrhunderts Y1 - 2022 SN - 978-3-89986-380-2 VL - 2022 SP - 6 EP - 17 PB - avedition CY - Stuttgart ER - TY - JOUR A1 - Schulte-Tigges, Joschua A1 - Förster, Marco A1 - Nikolovski, Gjorgji A1 - Reke, Michael A1 - Ferrein, Alexander A1 - Kaszner, Daniel A1 - Matheis, Dominik A1 - Walter, Thomas T1 - Benchmarking of various LiDAR sensors for use in self-driving vehicles in real-world environments JF - Sensors N2 - Abstract In this paper, we report on our benchmark results of the LiDAR sensors Livox Horizon, Robosense M1, Blickfeld Cube, Blickfeld Cube Range, Velodyne Velarray H800, and Innoviz Pro. The idea was to test the sensors in different typical scenarios that were defined with real-world use cases in mind, in order to find a sensor that meet the requirements of self-driving vehicles. For this, we defined static and dynamic benchmark scenarios. In the static scenarios, both LiDAR and the detection target do not move during the measurement. In dynamic scenarios, the LiDAR sensor was mounted on the vehicle which was driving toward the detection target. We tested all mentioned LiDAR sensors in both scenarios, show the results regarding the detection accuracy of the targets, and discuss their usefulness for deployment in self-driving cars. KW - Lidar KW - Benchmark KW - Self-driving Y1 - 2022 U6 - https://doi.org/10.3390/s22197146 SN - 1424-8220 N1 - This article belongs to the Special Issue "Sensor Fusion for Vehicles Navigation and Robotic Systems" VL - 22 IS - 19 PB - MDPI CY - Basel ER - TY - PAT A1 - Hüning, Felix A1 - Backes, Andreas T1 - Wiegand-Modul N2 - Ein Wiegand-Modul (110;210;310) umfassend- eine Sensorspule (112;212;312),- einen ersten Wiegand-Draht (116a;216a;316a), der zumindest teilweise innerhalb der Sensorspule (112;212;312) angeordnet ist, und- einen zweiten Wiegand-Draht (116b;216b;316b), der zumindest teilweise innerhalb der Sensorspule (112;212;312) angeordnet ist und sich im Wesentlichen parallel zu dem ersten Wiegand-Draht (116a;216a;316a) erstreckt, ist bekannt.Um eine effiziente Ausnutzung der durch die Ummagnetisierung der Wiegand-Drähte (116a,116b;216a,216b;316a,316b) in die Sensorspule (112;212;312) induzierten elektrischen Energie zu ermöglichen, sind der erste Wiegand-Draht (116a;216a;316a) und der zweite Wiegand-Draht (116b;216b;316b) bezogen auf eine axiale Richtung der Sensorspule (112;212;312) versetzt zueinander angeordnet. Y1 - 2023 N1 - Patent DE102021115745B3 2022.07.21 ER - TY - GEN A1 - Rothkranz, Berit A1 - Krafft, Simone A1 - Tippkötter, Nils T1 - Media optimization for sustainable fuel production: How to produce biohydrogen from renewable resources with Thermotoga neapolitana T2 - Chemie Ingenieur Technik N2 - Hydrogen is playing an increasingly important role in research and politics as an energy carrier of the future. Since hydrogen has commonly been produced from methane by steam reforming, the need for climate-friendly, alternative production routes is emerging. In addition to electrolysis, fermentative routes for the production of so-called biohydrogen are "green" alternatives. The application of microorganisms offers the advantage of sustainable production from renewable resources using easily manageable technologies. In this project, the hyperthermophilic, anaerobic microorganism Thermotoga neapolitana is used for the productio nof biohydrogen from renewable resources. The enzymatically hydrolyzed resources were used in fermentation leading to yield coefficients of 1.8 mole H₂ per mole glucose when using hydrolyzed straw and ryegrass supplemented with medium, respectively. These results are similar to the hydrogen yields when using Thermotoga basal medium with glucose (TBGY) as control group. In order to minimize the supplementation of the hydrolysate and thus increase the economic efficiency of the process, the essential media components were identified. The experiments revealed NaCl, KCl, and glucose as essential components for cell growth as well as biohydrogen production. When excluding NaCl, a decrease of 96% in hydrogen production occured. Y1 - 2022 U6 - https://doi.org/10.1002/cite.202255305 SN - 0009-286X SN - 1522-2640 (eISSN) N1 - ProcessNet and DECHEMA‐BioTechNet Jahrestagungen 2022 together with 13th ESBES Symposium 2022, 12. - 15. September 2022, Eurogress Aachen VL - 94 IS - 9 SP - 1298 EP - 1299 PB - Wiley-VCH CY - Weinheim ER - TY - GEN A1 - Varriale, Ludovica A1 - Kuka, Katrin A1 - Tippkötter, Nils A1 - Ulber, Roland T1 - Use of a green biomass in a biorefinery platform T2 - Chemie Ingenieur Technik N2 - The emerging environmental issues due to the use of fossil resources are encouraging the exploration of new renewable resources. Biomasses are attracting more interest due to the low environmental impacts, low costs, and high availability on earth. In this scenario, green biorefineries are a promising platform in which green biomasses are used as feedstock. Grasses are mainly composed of cellulose and hemicellulose, and lignin is available in a small amount. In this work, a perennial ryegrass was used as feedstock to develop a green bio-refinery platform. Firstly, the grass was mechanically pretreated, thus obtaining a press juice and a press cake fraction. The press juice has high nutritional values and can be employed as part of fermentation media. The press cake can be employed as a substrate either in enzymatic hydrolysis or in solid-state fermentation. The overall aim of this work was to demonstrate different applications of both the liquid and the solid fractions. For this purpose, the filamentous fungus A. niger and the yeast Y. lipolythica were selected for their ability to produce citric acid. Finally, the possibility was assessed to use the press juice as part of fermentation media to cultivate S. cerevisiae and lactic acid bacteria for ethanol and lactic acid fermentation. Y1 - 2022 U6 - https://doi.org/10.1002/cite.202255095 SN - 0009-286X SN - 1522-2640 (eISSN) N1 - ProcessNet and DECHEMA‐BioTechNet Jahrestagungen 2022 together with 13th ESBES Symposium 2022, 12. - 15. September 2022, Eurogress Aachen VL - 94 IS - 9 SP - 1299 PB - Wiley-VCH CY - Weinheim ER - TY - BOOK A1 - Kurz, Melanie A1 - Schwer, Thilo T1 - Geschichte des Designs N2 - Dieser Band bietet einen kompakten Überblick über die wichtigsten Stationen des Produktdesigns vom Beginn der Industrialisierung bis heute. Im Zentrum stehen ikonische Alltagsgegenstände vom Thonet-Stuhl bis zum iPhone. Anschaulich und kenntnisreich nehmen Melanie Kurz und Thilo Schwer dabei auch die gesellschaftspolitische Situation, in der die Objekte entstanden sind, in den Blick. Y1 - 2022 SN - 978-3-406-78813-0 PB - Beck CY - München ET - 1. Auflage ER - TY - JOUR A1 - Hoffmann, Andreas A1 - Uhl, Matthias A1 - Ceblin, Maximilian A1 - Rohrbach, Felix A1 - Bansmann, Joachim A1 - Mallah, Marcel A1 - Heuermann, Holger A1 - Jacob, Timo A1 - Kuehne, Alexander J.C. T1 - Atmospheric pressure plasma-jet treatment of PAN-nonwovens—carbonization of nanofiber electrodes JF - C - Journal of Carbon Research N2 - Carbon nanofibers are produced from dielectric polymer precursors such as polyacrylonitrile (PAN). Carbonized nanofiber nonwovens show high surface area and good electrical conductivity, rendering these fiber materials interesting for application as electrodes in batteries, fuel cells, and supercapacitors. However, thermal processing is slow and costly, which is why new processing techniques have been explored for carbon fiber tows. Alternatives for the conversion of PAN-precursors into carbon fiber nonwovens are scarce. Here, we utilize an atmospheric pressure plasma jet to conduct carbonization of stabilized PAN nanofiber nonwovens. We explore the influence of various processing parameters on the conductivity and degree of carbonization of the converted nanofiber material. The precursor fibers are converted by plasma-jet treatment to carbon fiber nonwovens within seconds, by which they develop a rough surface making subsequent surface activation processes obsolete. The resulting carbon nanofiber nonwovens are applied as supercapacitor electrodes and examined by cyclic voltammetry and impedance spectroscopy. Nonwovens that are carbonized within 60 s show capacitances of up to 5 F g⁻¹. Y1 - 2022 U6 - https://doi.org/10.3390/c8030033 SN - 2311-5629 N1 - This article belongs to the Collection "Nanoporous Carbon Materials for Advanced Technological Applications" VL - 8 IS - 3 PB - MDPI CY - Basel ER - TY - JOUR A1 - Mueller, Tobias A1 - Segin, Alexander A1 - Weigand, Christoph A1 - Schmitt, Robert H. T1 - Feature selection for measurement models JF - International journal of quality & reliability management N2 - Purpose In the determination of the measurement uncertainty, the GUM procedure requires the building of a measurement model that establishes a functional relationship between the measurand and all influencing quantities. Since the effort of modelling as well as quantifying the measurement uncertainties depend on the number of influencing quantities considered, the aim of this study is to determine relevant influencing quantities and to remove irrelevant ones from the dataset. Design/methodology/approach In this work, it was investigated whether the effort of modelling for the determination of measurement uncertainty can be reduced by the use of feature selection (FS) methods. For this purpose, 9 different FS methods were tested on 16 artificial test datasets, whose properties (number of data points, number of features, complexity, features with low influence and redundant features) were varied via a design of experiments. Findings Based on a success metric, the stability, universality and complexity of the method, two FS methods could be identified that reliably identify relevant and irrelevant influencing quantities for a measurement model. Originality/value For the first time, FS methods were applied to datasets with properties of classical measurement processes. The simulation-based results serve as a basis for further research in the field of FS for measurement models. The identified algorithms will be applied to real measurement processes in the future. KW - Feature selection KW - Modelling KW - Measurement models KW - Measurement uncertainty Y1 - 2022 U6 - https://doi.org/10.1108/IJQRM-07-2021-0245 SN - 0265-671X IS - Vol. ahead-of-print, No. ahead-of-print. PB - Emerald Group Publishing Limited CY - Bingley ER - TY - JOUR A1 - Gaigall, Daniel A1 - Gerstenberg, Julian A1 - Trinh, Thi Thu Ha T1 - Empirical process of concomitants for partly categorial data and applications in statistics JF - Bernoulli N2 - On the basis of independent and identically distributed bivariate random vectors, where the components are categorial and continuous variables, respectively, the related concomitants, also called induced order statistic, are considered. The main theoretical result is a functional central limit theorem for the empirical process of the concomitants in a triangular array setting. A natural application is hypothesis testing. An independence test and a two-sample test are investigated in detail. The fairly general setting enables limit results under local alternatives and bootstrap samples. For the comparison with existing tests from the literature simulation studies are conducted. The empirical results obtained confirm the theoretical findings. KW - bootstrap KW - Categorial variable KW - Concomitant KW - Empirical process KW - Independence test Y1 - 2022 U6 - https://doi.org/10.3150/21-BEJ1367 SN - 1573-9759 VL - 28 IS - 2 SP - 803 EP - 829 PB - International Statistical Institute CY - Den Haag, NL ER - TY - JOUR A1 - Funke, Harald A1 - Esch, Thomas A1 - Roosen, Petra T1 - Powertrain Adaptions for LPG Usage in General Aviation JF - MTZ worldwide N2 - In general aviation, too, it is desirable to be able to operate existing internal combustion engines with fuels that produce less CO₂ than Avgas 100LL being widely used today It can be assumed that, in comparison, the fuels CNG, LPG or LNG, which are gaseous under normal conditions, produce significantly lower emissions. Necessary propulsion system adaptations were investigated as part of a research project at Aachen University of Applied Sciences. Y1 - 2022 U6 - https://doi.org/10.1007/s38313-021-0756-6 VL - 2022 IS - 83 SP - 58 EP - 62 PB - Springer Nature CY - Basel ER - TY - JOUR A1 - Fabo, Sabine ED - Wirth, Jacob T1 - Das Parasitäre in der Pandemie JF - Parasite Art Y1 - 2022 IS - Issue 2 SP - 8 EP - 11 PB - Parasite Art ER - TY - JOUR A1 - Ditzhaus, Marc A1 - Gaigall, Daniel T1 - Testing marginal homogeneity in Hilbert spaces with applications to stock market returns JF - Test N2 - This paper considers a paired data framework and discusses the question of marginal homogeneity of bivariate high-dimensional or functional data. The related testing problem can be endowed into a more general setting for paired random variables taking values in a general Hilbert space. To address this problem, a Cramér–von-Mises type test statistic is applied and a bootstrap procedure is suggested to obtain critical values and finally a consistent test. The desired properties of a bootstrap test can be derived that are asymptotic exactness under the null hypothesis and consistency under alternatives. Simulations show the quality of the test in the finite sample case. A possible application is the comparison of two possibly dependent stock market returns based on functional data. The approach is demonstrated based on historical data for different stock market indices. Y1 - 2022 U6 - https://doi.org/10.1007/s11749-022-00802-5 SN - 1863-8260 VL - 2022 IS - 31 SP - 749 EP - 770 PB - Springer ER -