TY - JOUR A1 - Teschers, Reimar A1 - Markhöfer, Jörg A1 - Mandelartz, Johannes T1 - Aluminiumrückführung aus dem Automobilbereich JF - Erzmetall : Rohstoffgewinnung, Verarbeitung, Recycling, Umwelttechnik Y1 - 1999 SN - 0044-2658 VL - Bd. 52 IS - Nr. 10 SP - 533 EP - 540 ER - TY - JOUR A1 - Teumer, T. A1 - Capitain, C. A1 - Ross-Jones, J. A1 - Tippkötter, Nils A1 - Rädle, M. A1 - Methner, F.-J. T1 - In-line Haze Monitoring Using a Spectrally Resolved Back Scattering Sensor JF - BrewingScience N2 - In the present work an optical sensor in combination with a spectrally resolved detection device for in-line particle-size-monitoring for quality control in beer production is presented. The principle relies on the size and wavelength dependent backscatter of growing particles in fluids. Measured interference structures of backscattered light are compared with calculated theoretical values, based on Mie-Theory, and fitted with a linear least square method to obtain particle size distributions. For this purpose, a broadband light source in combination with a process-CCD-spectrometer (charge ? coupled device spectrometer) and process adapted fiber optics are used. The goal is the development of an easy and flexible measurement device for in-line-monitoring of particle size. The presented device can be directly installed in product fill tubes or vessels, follows CIP- (cleaning in place) and removes the need of sample taking. A proof of concept and preliminary results, measuring protein precipitation, are presented. Y1 - 2018 SN - 1613-2041 VL - 71 IS - 5/6 SP - 49 EP - 55 PB - Fachverlag Hans Carl CY - Nürnberg ER - TY - JOUR A1 - Thelen, Jan A1 - Paschmann, Hans A1 - Hamelmann, Dirk T1 - Zielsichere Herstellung und Anwendung von Flüssigboden JF - bi-UmweltBau Y1 - 2010 N1 - in der Bereichsbibliothek Bayernallee gedruckt vorhanden SP - 48 EP - 49 ER - TY - JOUR A1 - Theysohn, Jens M. A1 - Kraff, Oliver A1 - Eilers, Kristina A1 - Andrade, Dorian A1 - Gerwig, Marcus A1 - Timmann, Dagmar A1 - Schmitt, Franz A1 - Ladd, Mark E. A1 - Ladd, Susanne C. A1 - Bitz, Andreas T1 - Vestibular effects of a 7 Tesla MRI examination compared to 1.5 T and 0 T in healthy volunteers JF - PLoS one N2 - Ultra-high-field MRI (7 Tesla (T) and above) elicits more temporary side-effects compared to 1.5 T and 3 T, e.g. dizziness or “postural instability” even after exiting the scanner. The current study aims to assess quantitatively vestibular performance before and after exposure to different MRI scenarios at 7 T, 1.5 T and 0 T. Sway path and body axis rotation (Unterberger's stepping test) were quantitatively recorded in a total of 46 volunteers before, 2 minutes after, and 15 minutes after different exposure scenarios: 7 T head MRI (n = 27), 7 T no RF (n = 22), 7 T only B₀ (n = 20), 7 T in & out B₀ (n = 20), 1.5 T no RF (n = 20), 0 T (n = 15). All exposure scenarios lasted 30 minutes except for brief one minute exposure in 7 T in & out B₀. Both measures were documented utilizing a 3D ultrasound system. During sway path evaluation, the experiment was repeated with eyes both open and closed. Sway paths for all long-lasting 7 T scenarios (normal, no RF, only B₀) with eyes closed were significantly prolonged 2 minutes after exiting the scanner, normalizing after 15 minutes. Brief exposure to 7 T B₀ or 30 minutes exposure to 1.5 T or 0 T did not show significant changes. End positions after Unterberger's stepping test were significantly changed counter-clockwise after all 7 T scenarios, including the brief in & out B₀ exposure. Shorter exposure resulted in a smaller alteration angle. In contrast to sway path, reversal of changes in body axis rotation was incomplete after 15 minutes. 1.5 T caused no rotational changes. The results show that exposure to the 7 Tesla static magnetic field causes only a temporary dysfunction or “over-compensation” of the vestibular system not measurable at 1.5 or 0 Tesla. Radiofrequency fields, gradient switching, and orthostatic dysregulation do not seem to play a role. Y1 - 2014 U6 - https://doi.org/10.1371/journal.pone.0092104 SN - 1932-6203 VL - 9 IS - 3 PB - PLOS CY - San Francisco ER - TY - JOUR A1 - Thiebes, Anja Lena A1 - Klein, Sarah A1 - Zingsheim, Jonas A1 - Möller, Georg H. A1 - Gürzing, Stefanie A1 - Reddemann, Manuel A. A1 - Behbahani, Mehdi A1 - Cornelissen, Christian G. T1 - Effervescent atomizer as novel cell spray technology to decrease the gas-to-liquid ratio JF - pharmaceutics N2 - Cell spraying has become a feasible application method for cell therapy and tissue engineering approaches. Different devices have been used with varying success. Often, twin-fluid atomizers are used, which require a high gas velocity for optimal aerosolization characteristics. To decrease the amount and velocity of required air, a custom-made atomizer was designed based on the effervescent principle. Different designs were evaluated regarding spray characteristics and their influence on human adipose-derived mesenchymal stromal cells. The arithmetic mean diameters of the droplets were 15.4–33.5 µm with decreasing diameters for increasing gas-to-liquid ratios. The survival rate was >90% of the control for the lowest gas-to-liquid ratio. For higher ratios, cell survival decreased to approximately 50%. Further experiments were performed with the design, which had shown the highest survival rates. After seven days, no significant differences in metabolic activity were observed. The apoptosis rates were not influenced by aerosolization, while high gas-to-liquid ratios caused increased necrosis levels. Tri-lineage differentiation potential into adipocytes, chondrocytes, and osteoblasts was not negatively influenced by aerosolization. Thus, the effervescent aerosolization principle was proven suitable for cell applications requiring reduced amounts of supplied air. This is the first time an effervescent atomizer was used for cell processing. KW - tri-lineage differentiation KW - survival KW - twin-fluid atomizer KW - adipose-derived stromal cells (ASCs) KW - cell atomization KW - cell aerosolization Y1 - 2022 U6 - https://doi.org/10.3390/pharmaceutics14112421 N1 - This article belongs to the Special Issue "Stromal, Stem, Signaling Cells: The Multiple Roles and Applications of Mesenchymal Cells" VL - 14 IS - 11 PB - MDPI CY - Basel ER - TY - JOUR A1 - Thiel, Alexander A1 - Muffler, Kai A1 - Tippkötter, Nils A1 - Suck, Kirstin A1 - Sohling, Ulrich A1 - Hruschka, Steffen M. A1 - Ulber, Roland T1 - A novel integrated downstream processing approach to recover sinapic acid, phytic acid and proteins from rapeseed meal JF - Journal of Chemical Technology and Biotechnology N2 - BACKGROUND Currently, several techniques exist for the downstream processing of protein, phytic acid and sinapic acid from rapeseed and rapeseed meal, but no technique has been developed to separate all of the components in one process. In this work, two new downstream processing strategies focusing on recovering sinapic acid, phytic acid and protein from rapeseed meal were established. RESULTS The sinapic acid content was enhanced by a factor of 4.5 with one method and 5.1 with the other. The isolation of sinapic acid was accomplished using a zeolite-based adsorbent with high adsorptive and optimal desorption characteristics. Phytic acid was isolated using the anion-exchange resin Purolite A200®. In addition, the processes resulted in two separated protein fractions. The ratios of globulin and albumin ratio to the total protein were 59.2% and 40.1%, respectively. The steps were then combined in two different ways: (a) a ‘sequential process’ using the zeolite and A200 in batch processes; and (b) a ‘parallel process’ using only A200 in a chromatographic system to separate all of the compounds. CONCLUSIONS It can be concluded that isolation of all three components was possible in both processes. These could enhance the added value of current processes using rapeseed meal as a protein source. © 2015 Society of Chemical Industry Y1 - 2015 U6 - https://doi.org/10.1002/jctb.4664 VL - 90 IS - 11 SP - 1999 EP - 2006 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Thiel, Alexander A1 - Muffler, Kai A1 - Tippkötter, Nils A1 - Suck, Kirstin A1 - Sohling, Ulrich A1 - Ruf, Friedrich A1 - Ulber, Roland T1 - Aufarbeitung von Polyphenolen aus Weizen mittels Zeolithen am Beispiel der Ferulasäure JF - Chemie IngenieurTechnik N2 - Aufarbeitung von Polyphenolen aus Weizenmittels Zeolithen am Beispiel der Ferulasa¨ ureAlexander Thiel1, Kai Muffler1, Nils Tippko¨ tter1, Kirstin Suck2, Ulrich Sohling2, Friedrich Ruf3und Roland Ulber1,*DOI: 10.1002/cite.201400031Bei der Ferulasa¨ure handelt es sich um einen Wertstoff, der aus Weizen gewonnen und in der Lebensmittel- und Pharma-industrie eingesetzt werden kann. Der Einsatz von Weizen als nachwachsende Rohstoffquelle ist allerdings nur dann wirt-schaftlich durchfu¨hrbar, wenn eine Prozessintegration in die bestehenden industriellen Verfahren gewa¨hrleistet oder einedirekte Konkurrenz zur Mehl- und Sta¨rkeindustrie vermieden werden kann. In diesem Artikel wird ein Verfahren aufge-zeigt, welches hohe Ausbeuten ermo¨glicht und eine Konkurrenz zu bestehenden Verwertungspfaden vermeidet. Y1 - 2015 U6 - https://doi.org/10.1002/cite.201400031 N1 - Englischer Titel: Downstream Processing of Polyphenols from Wheat by Zeolites using the Example of Ferulic Acid VL - 87 IS - 1-2 SP - 128 EP - 136 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Thiel, Alexander A1 - Tippkötter, Nils A1 - Suck, Kirstin A1 - Sohling, Ulrich A1 - Ruf, Friedrich A1 - Ulber, Roland T1 - New zeolite adsorbents for downstream processing of polyphenols from renewable resources JF - Engineering in Life Sciences N2 - Commercial materials with polyvinylpolypyrrolidone and polymeric amberlites (XAD7HP, XAD16) are commonly used for the adsorptive downstream processing of polyphenols from renewable resources. In this study, beta-zeolite-based adsorbent systems were examined, and their properties were compared to organic resins. Batch adsorption experiments were conducted with synthetic solutions of major polyphenols. Adsorption isotherms and desorption characteristics of individual adsorbent were determined based on these results. Maximum adsorption capacities were calculated using the Langmuir model. For example, the zeolites had capacities up to 203.2 mg/g for ferulic acid. To extend these results to a complex system, additional experiments were performed on rapeseed meal and wheat seed extracts as representative renewable resources. HPLC analysis showed that with 7.5% w/v, which is regarded as the optimum amount of zeolites, zeolites A and B could bind 100% of the major polyphenols as well as release polyphenols at high yields. Additionally, regeneration experiments were performed with isopropyl alcohol at 99°C to evaluate how zeolites regenerate under mild conditions. The results showed only a negligible loss of adsorption capacity and no loss of desorption capacity. In summary, it was concluded that beta-zeolites were promising adsorbents for developing new processes to isolate polyphenols from renewable resources. Y1 - 2013 U6 - https://doi.org/10.1002/elsc.201200188 VL - 13 IS - 3 SP - 239 EP - 246 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Thiel, Dieter A1 - Döring, Bernd T1 - Dezentrale Raumklimatisierung durch die Fassade JF - TAB Technik am Bau Y1 - 2001 SN - 0341-2032 VL - Bd. 32 IS - H. 3 SP - 67 EP - 76 ER - TY - JOUR A1 - Thielemann, Frank T1 - Chancen durch Online-Dienste? JF - OP DruckMagazin. 39 (1997), H. 1-2 Y1 - 1997 SN - 0030-0594 SP - 26 EP - f. ER - TY - JOUR A1 - Thielemann, Frank T1 - Das Management von Innovationen aus betriebswirtschaftlicher Sicht JF - Humanität - Wandel - Utopie / Bernd Rebe (Hrsg.). Mit Beitr. von Ute Daniel Y1 - 2000 N1 - Cloppenburger Wirtschaftsgespräche ; Bd. 9 SP - 33 EP - 64 PB - Olms CY - Hildesheim ER - TY - JOUR A1 - Thielemann, Frank T1 - Druckindustrielle Innovation JF - Der Siebdruck. 47 (1998), H. 4 Y1 - 1998 SN - 0178-2835 SP - 32 EP - ff ER - TY - JOUR A1 - Thielemann, Frank T1 - Mit vereinten Kräften JF - Trockenbau, Akustik : Magazin für Planung und Ausführung. 15 (1998), H. 5 Y1 - 1998 SN - 0179-8006 SP - 60 EP - 68 ER - TY - JOUR A1 - Thielemann, Frank T1 - Mit strategischen Allianzen ins nächste Jahrtausend JF - Druckspiegel. 53 (1998), H. 5 Y1 - 1998 SN - 0012-6500 SP - 21 EP - 24 ER - TY - JOUR A1 - Thielemann, Frank A1 - Bock, Jürgen T1 - Aufbau und Management deutsch-russischer Joint-ventures. Bock Jürgen; Thielemann, Frank JF - Mit Innovation vom Plan zum Markt Y1 - 1993 SP - 111 EP - 135 CY - Bochum ER - TY - JOUR A1 - Thielemann, Frank A1 - Bock, Jürgen T1 - Organization and management of German-Russian joint ventures. Bock, Jürgen; Thielemann, Frank JF - International journal of technology management. 9 (1994), H. 8 Y1 - 1994 SN - 0267-5730 SP - 864 EP - 879 ER - TY - JOUR A1 - Thielemann, Frank A1 - Chalupsky, J. T1 - Der Markt verlangt nach Kooperationen JF - Leipziger Wirtschaft. 5 (1994), H. 6 Y1 - 1994 SP - 14 EP - 18 ER - TY - JOUR A1 - Thielemann, Frank A1 - Kriegesmann, Bernd A1 - Schaffner, M. T1 - Mit vereinten Kräften die Wettbewerbsfähigkeit steigern - Kooperation als Antwort auf den In­novationsdruck . Kriegesmann, B.; Thielemann, F.; Schaffner, M. JF - Der Druckspiegel. 50 (1995), H. 10 Y1 - 1995 SN - 0012-6500 SP - 931 EP - 935 ER - TY - JOUR A1 - Thielemann, Frank A1 - Lang, Franz Peter T1 - Wissensmanagement und neue Informationstechnologie . Lang, Franz Peter; Thielemann, Frank JF - Veränderungsmanagement in der Sozialwirtschaft / Bernd Maelicke (Hrsg.) Y1 - 2000 SN - 3-7890-6738-5 N1 - Inhaltsverzeichnis SP - 132 EP - 172 PB - Nomos-Verl.-Ges. CY - Baden-Baden ER - TY - JOUR A1 - Thielemann, Frank A1 - Lüdtke, C. T1 - Balanced Scorecard - Von der Vision zur Strategie JF - Wirtschafts-Nachrichten. 46 (2001), H. 9 Y1 - 2001 SN - 1436-5588 SP - 10 EP - f. ER -