TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Rechts- und Parteifähigkeit der Gesellschaft bürgerlichen Rechts JF - Juristische Schulung (2001) Y1 - 2001 SP - 536 EP - 540 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Anmerkung zu EuGH RS C-208/00 (Niederlassungsfreiheit und Internationales Gesellschaftsrecht) JF - Juristische Arbeitsblätter (2003) Y1 - 2003 SP - 267 EP - 270 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Anmerkung zu OLG Oldenburg 2 U 149/02 (Berufungszurückweisung durch Beschluß) JF - Juristische Arbeitsblätter (2003) Y1 - 2003 SP - 360 EP - 362 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Das Ende der Sitztheorie im Internationalen Gesellschaftsrecht?- EuGH, EuZW 1999, 216 JF - Juristische Schulung (1999) Y1 - 1999 SP - 1055 EP - 1058 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Anmerkung zu BGH, NJW 2000, 142 (Zurückweisung verspäteten Vorbringens gem. § 296a ZPO) JF - Juristische Arbeitsblätter (2000) Y1 - 2000 SP - 359 EP - 361 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Zweites Versäumnisurteil und Berufungsmöglichkeiten gemäß § 513 II ZPO JF - Juristische Arbeitsblätter (2000) Y1 - 2000 SP - 788 EP - 791 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Anmerkung zu BGH IV ZB 20/03 (Zivilprozeßrecht) JF - Monatsschrift für deutsches Recht : MDR (2004) Y1 - 2004 SP - 466 EP - 468 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Anmerkung zu BGH VI ZR 109/03 (Schadensersatzrecht) JF - Monatsschrift für deutsches Recht : MDR (2004) Y1 - 2004 SP - 935 EP - 936 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Anmerkung zu BGH IX ZR 229/03 (Zivilprozessrecht) JF - Monatsschrift für deutsches Recht : MDR (2005) Y1 - 2005 SP - 527 EP - 530 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Schriftform bei Mietvertrag mit einer Aktiengesellschaft JF - Neue Zeitschrift für Gesellschaftsrecht (NZG) Y1 - 2010 SN - 1434-9272 VL - 13 IS - 5 SP - 177 EP - 178 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Schriftform bei langfristigen Mietverträgen - ein Dauerproblem JF - Neue juristische Wochenschrift : NJW. 60 (2007), H. 46 Y1 - 2007 SN - 0341-1915 N1 - in der Bereichsbibliothek Eupener Str. vorhanden unter 43 Z 093 SP - 3313 EP - 3317 ER - TY - JOUR A1 - Timme, Michael A1 - Hülk, Fabian T1 - Mieterhöhungsverlangen bei unwirksamer Schönheitsreparaturklausel JF - Monatsschrift für deutsches Recht : MdR ; Zeitschrift für die Zivilrechtspraxis. 28 (2008), H. 22 Y1 - 2008 SN - 0340-1812 SP - 1249 EP - 1251 ER - TY - JOUR A1 - Timme, Michael A1 - Raue, Benjamin T1 - Ausschluss des Zurückbehaltungsrechts bei fehlender Mängelanzeige JF - Neue Zeitschrift für Miet- und Wohnungsrecht [Elektronische Ressource] : NZM ; Miete, Wohnungseigentum, Pacht, Makler- und Bauträgerrecht, Steuern, Wohnungswirtschaft, Versicherung, Immobilienleasing Y1 - 2011 SN - 1434-677X VL - 14 IS - 23 SP - 846 EP - 849 PB - Beck CY - München ER - TY - JOUR A1 - Timme, Michael A1 - Voß, Wulf Eckart T1 - Anmerkung zu BGH, Urteil vom 18.6.1997 (Mietrecht) JF - Juristenzeitung (1998) Y1 - 1998 SP - 304 EP - 306 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Al-Kaidy, Huschyar A1 - Wollny, Steffen A1 - Ulber, Roland T1 - Functionalized magnetizable particles for downstream processing in single-use systems JF - Chemie Ingenieur Technik N2 - Biotechnological downstream processing is usually an elaborate procedure, requiring a multitude of unit operations to isolate the target component. Besides the disadvantageous space-time yield, the risks of cross-contaminations and product loss grow fast with the complexity of the isolation procedure. A significant reduction of unit operations can be achieved by application of magnetic particles, especially if these are functionalized with affinity ligands. As magnetic susceptible materials are highly uncommon in biotechnological processes, target binding and selective separation of such particles from fermentation or reactions broths can be done in a single step. Since the magnetizable particles can be produced from iron salts and low priced polymers, a single-use implementation of these systems is highly conceivable. In this article, the principles of magnetizable particles, their synthesis and functionalization are explained. Furthermore, applications in the area of reaction engineering, microfluidics and downstream processing are discussed focusing on established single-use technologies and development potential. Y1 - 2013 U6 - https://doi.org/10.1002/cite.201200130 VL - 85 IS - 1-2: Special Issue: Single-Use Technology SP - 76 EP - 86 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Tippkötter, Nils A1 - Deterding, A. A1 - Ulber, Roland T1 - Determination of acetic acid in fermentation broth by gas-diffusion technique JF - Engineering in Life Sciences N2 - Due to the interfering effects of acetic acid in many fermentation processes, a gas-diffusion technique was developed for the online determination of acetic acid. The measurements were accomplished with a flow diffusion analysis (FDA) unit from the TRACE Analytics GmbH, Braunschweig, Germany. The diffusion analysis is based on the UV-absorbance of acetic acid at 205 nm. The measurement was achieved by the separation of an acceptor and a carrier stream (acidified fermentation broth) using a gas permeable polytetrafluoroethylene (PTFE) membrane, whereby broth constituents that would otherwise disturb the UV-measurement of acetic acid, are held back efficiently. Merely, the fermentation by-products, e.g. formic acid, is capable of diffusing through the membrane. While formic acid can disturb the measurement, carbon dioxide does not absorb at 205 nm. The method operates with time-dependent sample enrichment. During the analysis, a small volume of the acceptor stream is stopped for a defined time interval in the acceptor chamber. During this period, the gaseous acetic acid diffuses through the membrane and is enriched in the acceptor chamber. Subsequently after the enrichment, the acceptor stream flows through a UV-detector. The intensity of the signal is proportional to the acetic acid concentration. Online measurements in bioreactors via a sterile filtration probe have been accomplished. A linear calibration in the range of 0.5–5.0 g/L acetic acid with a relative standard deviation of <5 % was obtained. A sampling rate of 8 samples per hour was possible. The system was applied for the determination of acetic acid in E. coli fermentation broth. The instrument is easy to clean, very user-friendly and does not require any toxic or expensive reagents. Y1 - 2008 U6 - https://doi.org/10.1002/elsc.200820227 VL - 8 IS - 1, Special Issue: Technical Systems for the Use in Life Sciences SP - 62 EP - 67 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Duwe, Anna-Maria A1 - Wiesen, Sebastian A1 - Sieker, Tim A1 - Ulber, Roland T1 - Enzymatic hydrolysis of beech wood lignocellulose at high solid contents and its utilization as substrate for the production of biobutanol and dicarboxylic acids JF - Bioresource Technology N2 - The development of a cost-effective hydrolysis for crude cellulose is an essential part of biorefinery developments. To establish such high solid hydrolysis, a new solid state reactor with static mixing is used. However, concentrations >10% (w/w) cause a rate and yield reduction of enzymatic hydrolysis. By optimizing the synergetic activity of cellulolytic enzymes at solid concentrations of 9%, 17% and 23% (w/w) of crude Organosolv cellulose, glucose concentrations of 57, 113 and 152 g L⁻¹ are reached. However, the glucose yield decreases from 0.81 to 0.72gg⁻¹ at 17% (w/w). Optimal conditions for hydrolysis scale-up under minimal enzyme addition are identified. As result, at 23% (w/w) crude cellulose the glucose yield increases from 0.29 to 0.49gg⁻¹. As proof of its applicability, biobutanol, succinic and itaconic acid are produced with the crude hydrolysate. The potential of the substrate is proven e.g. by a high butanol yield of 0.33gg⁻¹. Y1 - 2014 U6 - https://doi.org/10.1016/j.biortech.2014.06.052 VL - 167 SP - 447 EP - 455 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Tippkötter, Nils A1 - Roikaew, N. A1 - Ulber, Roland T1 - Nitratentfernung aus Molkekonzentrat mit biotechnologischer Regeneration der Abwässer JF - Deutsche Milchwirtschaft Y1 - 2007 SN - 0012-0480 VL - 58 IS - 15 SP - 540 EP - 542 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Roikaew, W. A1 - Ulber, Roland T1 - Nitrate removal from whey concentrate with biotechnological regeneration of the waste water JF - European dairy magazine : EDM Y1 - 2008 SN - 0936-6318 IS - 1 SP - 30 EP - 32 ER - TY - JOUR A1 - Tippkötter, Nils A1 - Roikaew, Wipa A1 - Ulber, Roland A1 - Hoffmann, Alexander A1 - Denzler, Hans-Jörg A1 - Buchholz, Heinrich T1 - Paracoccus denitrificans for the effluent recycling during continuous denitrification of liquid food JF - Biotechnology Progress N2 - Nitrate is an undesirable component of several foods. A typical case of contamination with high nitrate contents is whey concentrate, containing nitrate in concentrations up to 25 l. The microbiological removal of nitrate by Paracoccus denitrificans under formation of harmless nitrogen in combination with a cell retention reactor is described here. Focus lies on the resource-conserving design of a microbal denitrification process. Two methods are compared. The application of polyvinyl alcohol-immobilized cells, which can be applied several times in whey feed, is compared with the implementation of a two step denitrification system. First, the whey concentrate's nitrate is removed by ion exchange and subsequently the eluent regenerated by microorganisms under their retention by crossflow filtration. Nitrite and nitrate concentrations were determined by reflectometric color measurement with a commercially available Reflectoquant® device. Correction factors for these media had to be determined. During the pilot development, bioreactors from 4 to 250 mg·L-1 and crossflow units with membrane areas from 0.02 to 0.80 m2 were examined. Based on the results of the pilot plants, a scaling for the exemplary process of denitrifying 1,000 tons per day is discussed. Y1 - 2010 U6 - https://doi.org/10.1002/btpr.384 SN - 8756-7938 VL - 26 IS - 3 SP - 756 EP - 762 PB - Wiley CY - Hoboken, NJ ER -