TY - JOUR A1 - Achtsnicht, Stefan A1 - Neuendorf, Christian A1 - Faßbender, Tobias A1 - Nölke, Greta A1 - Offenhäusser, Andreas A1 - Krause, Hans-Joachim A1 - Schröper, Florian T1 - Sensitive and rapid detection of cholera toxin subunit B using magnetic frequency mixing detection JF - Plos One N2 - Cholera is a life-threatening disease caused by the cholera toxin (CT) as produced by some Vibrio cholerae serogroups. In this research we present a method which directly detects the toxin’s B subunit (CTB) in drinking water. For this purpose we performed a magnetic sandwich immunoassay inside a 3D immunofiltration column. We used two different commercially available antibodies to capture CTB and for binding to superparamagnetic beads. ELISA experiments were performed to select the antibody combination. The beads act as labels for the magnetic frequency mixing detection technique. We show that the limit of detection depends on the type of magnetic beads. A nonlinear Hill curve was fitted to the calibration measurements by means of a custom-written python software. We achieved a sensitive and rapid detection of CTB within a broad concentration range from 0.2 ng/ml to more than 700 ng/ml. Y1 - 2019 U6 - https://doi.org/10.1371/journal.pone.0219356 SN - 1932-6203 VL - 14 IS - 7 PB - Plos CY - San Francisco ER - TY - JOUR A1 - Cornelis, Peter A1 - Givanoudi, Stella A1 - Yongabi, Derick A1 - Iken, Heiko A1 - Duwé, Sam A1 - Deschaume, Olivier A1 - Robbens, Johan A1 - Dedecker, Peter A1 - Bartic, Carmen A1 - Wübbenhorst, Michael A1 - Schöning, Michael Josef A1 - Heyndrickx, Marc A1 - Wagner, Patrick T1 - Sensitive and specific detection of E. coli using biomimetic receptors in combination with a modified heat-transfer method JF - Biosensors and Bioelectronics Y1 - 2019 U6 - https://doi.org/10.1016/j.bios.2019.04.026 SN - 0956-5663 VL - 136 SP - 97 EP - 105 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dikta, Gerhard A1 - Degenring, D. A1 - Froemmel, C. A1 - Takors, R. T1 - Sensitivity analysis for the reduction of complex metabolism models / Degenring, D. ; Froemmel, C. ; Dikta, G.; Takors, R. JF - Journal of Process Control. 14 (2004) Y1 - 2004 SN - 0959-1524 SP - 729 EP - 745 ER - TY - JOUR A1 - Staat, Manfred T1 - Sensitivity of and Influences on the Reliability of an HTR-Module Primary Circuit Pressure Boundary JF - Transactions of the 12th International Conference on Structural Mechanics in Reactor Technology (SMiRT-12) / Kussmaul, K. [ed] Y1 - 1993 SN - 0-444-81515-5 N1 - Vol. M, Paper MG10/2 SP - 147 EP - 152 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bühler, Yves A1 - Christen, Marc A1 - Kowalski, Julia A1 - Bartelt, Perry T1 - Sensitivity of snow avalanche simulations to digital elevation model quality and resolution JF - Annals of Glaciology N2 - Digital elevation models (DEMs), represent the three-dimensional terrain and are the basic input for numerical snow avalanche dynamics simulations. DEMs can be acquired using topographic maps or remote-sensing technologies, such as photogrammetry or lidar. Depending on the acquisition technique, different spatial resolutions and qualities are achieved. However, there is a lack of studies that investigate the sensitivity of snow avalanche simulation algorithms to the quality and resolution of DEMs. Here, we perform calculations using the numerical avalance dynamics model RAMMS, varying the quality and spatial resolution of the underlying DEMs, while holding the simulation parameters constant. We study both channelized and open-terrain avalanche tracks with variable roughness. To quantify the variance of these simulations, we use well-documented large-scale avalanche events from Davos, Switzerland (winter 2007/08), and from our large-scale avalanche test site, Valĺee de la Sionne (winter 2005/06). We find that the DEM resolution and quality is critical for modeled flow paths, run-out distances, deposits, velocities and impact pressures. Although a spatial resolution of ~25 m is sufficient for large-scale avalanche modeling, the DEM datasets must be checked carefully for anomalies and artifacts before using them for dynamics calculations. KW - snow KW - avalanche Y1 - 2011 SN - 1727-5644 VL - 52 IS - 58 SP - 72 EP - 80 PB - Cambridge University Press CY - Cambridge ER - TY - JOUR A1 - Valero, Daniel A1 - Bung, Daniel Bernhard T1 - Sensitivity of turbulent Schmidt number and turbulence model to simulations of jets in crossflow JF - Environmental Modelling and Software N2 - Environmental discharges have been traditionally designed by means of cost-intensive and time-consuming experimental studies. Some extensively validated models based on an integral approach have been often employed for water quality problems, as recommended by USEPA (i.e.: CORMIX). In this study, FLOW-3D is employed for a full 3D RANS modelling of two turbulent jet-to-crossflow cases, including free surface jet impingement. Results are compared to both physical modelling and CORMIX to better assess model performance. Turbulence measurements have been collected for a better understanding of turbulent diffusion's parameter sensitivity. Although both studied models are generally able to reproduce jet trajectory, jet separation downstream of the impingement has been reproduced only by RANS modelling. Additionally, concentrations are better reproduced by FLOW-3D when the proper turbulent Schmidt number is used. This study provides a recommendation on the selection of the turbulence model and the turbulent Schmidt number for future outfall structures design studies. Y1 - 2016 U6 - https://doi.org/10.1016/j.envsoft.2016.04.030 SN - 1364-8152 (electronic) VL - 82 SP - 218 EP - 228 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schusser, Sebastian A1 - Krischer, M. A1 - Molin, D. G. M. A1 - Akker, N. M. S. van den A1 - Bäcker, Matthias A1 - Poghossian, Arshak A1 - Schöning, Michael Josef T1 - Sensor System for in-situ and Real-time Monitoring of Polymer (bio) degradation JF - Procedia Engineering N2 - A sensor system for investigating (bio)degradationprocesses of polymers is presented. The system utilizes semiconductor field-effect sensors and is capable of monitoring the degradation process in-situ and in real-time. The degradation of the polymer poly(d,l-lactic acid) is exemplarily monitored in solutions with different pH value, pH-buffer solution containing the model enzyme lipase from Rhizomucormiehei and cell-culture medium containing supernatants from stimulated and non-stimulated THP-1-derived macrophages mimicking activation of the immune system. Y1 - 2015 U6 - https://doi.org/10.1016/j.proeng.2015.08.815 SN - 1877-7058 N1 - Eurosensors 2015 VL - 120 SP - 948 EP - 951 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Dikta, Gerhard A1 - Kurtz, B. A1 - Stute, W. T1 - Sequential Fixed-Width Confidence Bands for Distribution Functions Under Random Censoring JF - Metrika. 36 (1989) Y1 - 1989 SN - 0026-1335 SP - 167 EP - 176 ER - TY - JOUR A1 - Kämper, Klaus-Peter A1 - Berg, U. A1 - Begemann, M. A1 - Hagemann, B. (u.a.) T1 - Series production and testing of a micro motor. Serienfertigung und Prüfung eines Mikromotors JF - Actuator 98 : 6th International Conference on New Actuators ; 17 - 19 June, 1998, Bremen, Germany ; conference proceedings / ed.: Hubert Borgmann ... Y1 - 1998 SN - 3-933339-00-6 N1 - Konferenz-Einzelbericht: ACTUATOR, Internat. Conf. on New Actuators SP - 552 EP - 555 PB - Messe Bremen CY - Bremen ER - TY - JOUR A1 - Czarnecki, Christian A1 - Winkelmann, Axel A1 - Spiliopoulou, Myra T1 - Services in electronic telecommunication markets: a framework for planning the virtualization of processes JF - Electronic Markets N2 - The potential of electronic markets in enabling innovative product bundles through flexible and sustainable partnerships is not yet fully exploited in the telecommunication industry. One reason is that bundling requires seamless de-assembling and re-assembling of business processes, whilst processes in telecommunication companies are often product-dependent and hard to virtualize. We propose a framework for the planning of the virtualization of processes, intended to assist the decision maker in prioritizing the processes to be virtualized: (a) we transfer the virtualization pre-requisites stated by the Process Virtualization Theory in the context of customer-oriented processes in the telecommunication industry and assess their importance in this context, (b) we derive IT-oriented requirements for the removal of virtualization barriers and highlight their demand on changes at different levels of the organization. We present a first evaluation of our approach in a case study and report on lessons learned and further steps to be performed. KW - Telecommunication KW - Services KW - Process virtualization KW - Product bundling KW - Transformation Y1 - 2010 U6 - https://doi.org/10.1007/s12525-010-0045-8 SN - 1422-8890 VL - 20 IS - 3-4 SP - 197 EP - 207 PB - Springer CY - Berlin ER - TY - JOUR A1 - Nachtrodt, Frederik A1 - Tietsch, Wolfgang A1 - Mostacci, Domiziano A1 - Scherer, Ulrich W. T1 - Set-up and first operation of a plasma oven for treatment of low level radioactive wastes JF - Nuclear technology and radiation protection Y1 - 2014 U6 - https://doi.org/10.2298/NTRP140SS47N SN - 1451-3994 VL - 29 IS - Suppl. SP - 47 EP - 51 PB - VINČA Institute of Nuclear Sciences CY - Belgrad ER - TY - JOUR A1 - Umutlu, Lale A1 - Kraff, Oliver A1 - Fischer, Anja A1 - Kinner, Sonja A1 - Maderwald, Stefan A1 - Nassenstein, Kai A1 - Nensa, Felix A1 - Grüneisen, Johannes A1 - Orzada, Stephan A1 - Bitz, Andreas A1 - Forsting, Michael A1 - Ladd, Mark E. A1 - Lauenstein, Thomas C. T1 - Seven-Tesla MRI of the female pelvis JF - European Radiology Y1 - 2013 U6 - https://doi.org/10.1007/s00330-013-2868-0 SN - 1432-1084 VL - 23 IS - 9 SP - 2364 EP - 2373 PB - Springer CY - Berlin ER - TY - JOUR A1 - Vu, Duc Khoi A1 - Staat, Manfred T1 - Shakedown analysis of structures made of materials with temperature-dependent yield stress JF - International Journal of Solids and Structures. 44 (2007), H. 13 Y1 - 2007 SN - 0020-7683 SP - 4524 EP - 4540 ER - TY - JOUR A1 - Tran, Thanh Ngoc A1 - Staat, Manfred T1 - Shakedown analysis of two dimensional structures by an edge-based smoothed finite element method Y1 - 2010 N1 - ECCM 2010, IV European Conference on Computational Mechanics, Paris, France, May 16-21, 2010. SP - 1 EP - 7 ER - TY - JOUR A1 - Staat, Manfred T1 - Shakedown and ratchetting under tension-torsion loadings: analysis and experiments N2 - Structural design analyses are conducted with the aim of verifying the exclusion of ratchetting. To this end it is important to make a clear distinction between the shakedown range and the ratchetting range. The performed experiment comprised a hollow tension specimen which was subjected to alternating axial forces, superimposed with constant moments. First, a series of uniaxial tests has been carried out in order to calibrate a bounded kinematic hardening rule. The load parameters have been selected on the basis of previous shakedown analyses with the PERMAS code using a kinematic hardening material model. It is shown that this shakedown analysis gives reasonable agreement between the experimental and the numerical results. A linear and a nonlinear kinematic hardening model of two-surface plasticity are compared in material shakedown analysis. KW - Einspielen KW - Einspielen KW - Ratchetting KW - Zug-Druck Belastung KW - shakedown KW - ratchetting KW - tension–torsion loading Y1 - 2003 ER - TY - JOUR A1 - Staat, Manfred A1 - Heitzer, M. A1 - Reiners, H. A1 - Schubert, F. T1 - Shakedown and ratchetting under tension–torsion loadings: analysis and experiments JF - Nuclear Engineering and Design. 225 (2003), H. 1 Y1 - 2003 SN - 0029-5493 SP - 11 EP - 26 ER - TY - JOUR A1 - Kowalski, Julia A1 - McElwaine, Jim N. T1 - Shallow two-component gravity-driven flows with vertical variation JF - Journal of Fluid Mechanics Y1 - 2013 SN - 0022-1120 VL - 714 SP - 434 EP - 462 PB - Cambridge Univ. Press CY - Cambridge ER - TY - JOUR A1 - Turdumamatov, Samat A1 - Belda, Aljoscha A1 - Heuermann, Holger T1 - Shaping a decoupled atmospheric pressure microwave plasma with antenna structures, Maxwell’s equations, and boundary conditions JF - IEEE Transactions on Plasma Science N2 - This article addresses the need for an innovative technique in plasma shaping, utilizing antenna structures, Maxwell’s laws, and boundary conditions within a shielded environment. The motivation lies in exploring a novel approach to efficiently generate high-energy density plasma with potential applications across various fields. Implemented in an E01 circular cavity resonator, the proposed method involves the use of an impedance and field matching device with a coaxial connector and a specially optimized monopole antenna. This setup feeds a low-loss cavity resonator, resulting in a high-energy density air plasma with a surface temperature exceeding 3500 o C, achieved with a minimal power input of 80 W. The argon plasma, resembling the shape of a simple monopole antenna with modeled complex dielectric values, offers a more energy-efficient alternative compared to traditional, power-intensive plasma shaping methods. Simulations using a commercial electromagnetic (EM) solver validate the design’s effectiveness, while experimental validation underscores the method’s feasibility and practical implementation. Analyzing various parameters in an argon atmosphere, including hot S -parameters and plasma beam images, the results demonstrate the successful application of this technique, suggesting its potential in coating, furnace technology, fusion, and spectroscopy applications. KW - 3-D printing KW - Furnace KW - Fusion KW - Hot S-parameter KW - Mode converter Y1 - 2024 U6 - https://doi.org/10.1109/TPS.2024.3383589 SN - 0093-3813 (Print) SN - 1939-9375 (Online) IS - Early Access SP - 1 EP - 9 PB - IEEE ER - TY - JOUR A1 - Keller, Johannes A1 - Rath, Volker A1 - Bruckmann, Johanna A1 - Mottaghy, Darius A1 - Clauser, Christoph A1 - Wolf, Andreas A1 - Seidler, Ralf A1 - Bücker, H. Martin A1 - Klitzsch, Norbert T1 - SHEMAT-Suite: An open-source code for simulating flow, heat and species transport in porous media JF - SoftwareX N2 - SHEMAT-Suite is a finite-difference open-source code for simulating coupled flow, heat and species transport in porous media. The code, written in Fortran-95, originates from geoscientific research in the fields of geothermics and hydrogeology. It comprises: (1) a versatile handling of input and output, (2) a modular framework for subsurface parameter modeling, (3) a multi-level OpenMP parallelization, (4) parameter estimation and data assimilation by stochastic approaches (Monte Carlo, Ensemble Kalman filter) and by deterministic Bayesian approaches based on automatic differentiation for calculating exact (truncation error-free) derivatives of the forward code. Y1 - 2020 U6 - https://doi.org/10.1016/j.softx.2020.100533 SN - 2352-7110 VL - 12 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kern, Alexander A1 - Zischank, Wolfgang J. A1 - Heidler, Fridolin A1 - Wiesinger, J. [u.a.] T1 - Shielding effectiveness of reinforced concrete cable ducts carrying partial lightning currents JF - Conference proceedings : 14th - 18th September 1998, [Burlington Hotel, Birmingham, United Kingdom] / organised by: School of Engineering and Advanced Technology, Staffordshire University, United Kingdom Y1 - 1998 N1 - International Conference on Lightning Protection <24, 1998, Birmingham> ; School of Engineering and Advanced Technology ; ICLP <4, 1998, Birmingham> CY - Birmingham ER -