TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Vilser, Walthatd
A1  - Nagel, Edgar
A1  - Lanzl, Ines M.
T1  - Retinal vessel reaction in response to chromatic flickering light / Kotliar, Konstantin E. ; Vilser, Walthard ; Nagel, Edgar ; Lanzl, Ines M.
JF  - Graefe's Archive for Clinical and Experimental Ophthalmology. 242 (2004), H. 5
Y1  - 2004
SN  - 1435-702X
SP  - 377
EP  - 392
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Bauer, S. M.
A1  - Zamuraev, L. A.
T1  - Model of the transversely isotropic spherical layer for estimation of intraocular pressure changes after intravitreal injections / Bauer, S. M. ; Zamuraev, L. A. ; Kotliar, K. E.
JF  - Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 10 (2006), H. 2
Y1  - 2006
SN  - 1812-5123
SP  - 41
EP  - 47
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlova, O. V.
A1  - Zaseeva, M. V.
T1  - Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part I Initial theoretical presuppositions, hypotheses and facts / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotli
JF  - Glaukoma (2006)
Y1  - 2006
N1  - Original in Russisch
SP  - 35
EP  - 53
PB  - -
ER  - 
TY  - JOUR
A1  - Maggakis-Kelemen, C.
A1  - Bork, M.
A1  - Kayser, Peter
A1  - Biselli, Manfred
A1  - Artmann, Gerhard
T1  - Biological and mechanical quality of red blood cells cultured from human umbilical cord blood stem cells
JF  - Medical and biological engineering and computing. 41 (2003), H. 3
Y1  - 2003
SN  - 0140-0118
SP  - 350
EP  - 356
ER  - 
TY  - JOUR
A1  - Kaul, D. K.
A1  - Koshkaryev, A.
A1  - Artmann, Gerhard
A1  - Barshtein, G.
A1  - Yedgar, S.
T1  - Additive effect of red blood cell rigidity and adherence to endothelial cells in inducing vascular resistance
JF  - American Journal of Physiology : Heart and Circulation Physiology . 295 (2008), H. 4
Y1  - 2008
SN  - 1522-1539
VL  - 295
IS  - 4
SP  - H1788
EP  - H1793
ER  - 
TY  - JOUR
A1  - Jiminez German, Salvador
A1  - Behbahani, Mehdi
A1  - Miettinen, Susanna
A1  - Grijpma, Dirk W.
A1  - Haimi, Suvi P.
T1  - Proliferation and differentiation of adipose stem cells towards smooth muscle cells on poly(trimethylene carbonate) membranes
JF  - Macromolecular symposia
Y1  - 2013
SN  - 0258-0322
VL  - Vol. 334
IS  - Iss. 1
SP  - 133
EP  - 142
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Fuest, Matthias
A1  - Kotliar, Konstantin
A1  - Walter, Peter
A1  - Plange, Niklas
T1  - Monitoring intraocular pressure changes after intravitreal Ranibizumab injection using rebound tonometry
JF  - Ophthalmic and physiological optics
Y1  - 2014
U6  - https://doi.org/10.1111/opo.12134
SN  - 1475-1313 (E-Journal); 0275-5408 (Print)
N1  - Special Issue: The Ageing Visual System
VL  - 34
IS  - 4
SP  - 438
EP  - 444
PB  - Wiley-Blackwell
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Cehreli, Ruksan
A1  - Akpinar, Hale
A1  - Temiz Artmann, Aysegül
A1  - Sagol, Ozgul
T1  - Effects of Glutamine and Omega-3 Fatty Acids on Erythrocyte Deformability and Oxidative Damage in Rat Model of Enterocolitis
JF  - Gastroenterology Research
Y1  - 2015
U6  - https://doi.org/10.14740/gr683w
SN  - 1918-2813
VL  - 8
IS  - 5
SP  - 265
EP  - 273
ER  - 
TY  - JOUR
A1  - Stadler, Alexander Maximilian
A1  - Garvey, Christopher J.
A1  - Embs, Jan Peter
A1  - Koza, Michael Marek
A1  - Unruh, Tobias
A1  - Artmann, Gerhard
A1  - Zaccai, Guiseppe
T1  - Picosecond dynamics in haemoglobin from different species: A quasielastic neutron scattering study
JF  - Biochimica et biophysica acta (BBA): General Subjects
Y1  - 2014
U6  - https://doi.org/10.1016/j.bbagen.2014.06.007
SN  - 1872-8006 (E-Journal); 0304-4165 (Print)
VL  - 1840
IS  - 10
SP  - 2989
EP  - 2999
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Martin-Gonzalez, Anabel
A1  - Kotliar, Konstantin
A1  - Rios-Martinez, Jorge
A1  - Lanzl, Ines
A1  - Navab, Nassir
T1  - Mediated-reality magnification for macular degeneration rehabilitation
JF  - Journal of Modern Optics
Y1  - 2014
U6  - https://doi.org/10.1080/09500340.2014.936110
SN  - 1362-3044
VL  - 61
IS  - 17
SP  - 1400
EP  - 1408
PB  - Taylor & Francis
CY  - London
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment.
 Part I. Ocular blood circulation and its quantitative estimation
JF  - National journal Glaucoma
Y1  - 2006
SN  - 2078-4104
VL  - Vol. 5
IS  - No. 3
SP  - 62
EP  - 73
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Biomechanical modeling of the aqueous humor outflow after non-penetrating glaucoma filtration surgery in the human eye
JF  - Acta of bioengineering and biomechanics
Y1  - 2002
SN  - 1509-409X
VL  - Vol. 4
IS  - Suppl. 1
SP  - 728
EP  - 729
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Kharoubi, A.
A1  - Schmidt-Trucksäß, A.
A1  - Halle, M.
A1  - Lanzl, I.
T1  - Does internal longitudinal microstructure of retinal veins change with age in medically healthy persons?
JF  - Acta Ophthalmologica
Y1  - 2009
SN  - 1600-0420 (E-Journal); 1755-3768 (E-Journal); 0001-639X (Print); 1395-3907 (Print); 1755-375X (Print)
VL  - Vol. 87
IS  - Suppl. S244
SP  - 0
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Kappmeyer, K.
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Spielen von Blasinstrumenten und Augeninnendruck
JF  - Zeitschrift für praktische Augenheilkunde & augenärztliche Fortbildung : ZPA
Y1  - 2009
SN  - 1436-0322
VL  - Bd. 30
SP  - 169
EP  - 171
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part III. Non-invasive methods of assessment of ocular blood flow. 2. Static and dynamic assessment of retinal vessel reaction to stimuli
JF  - National Journal Glaucoma
Y1  - 2007
SN  - 2078-4104
VL  - Vol. 6
IS  - No. 2
SP  - 64
EP  - 71
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part III. Non-invasive methods of assessment of ocular blood flow. 1. Assessment of blood cell velocities and flow rates in intraocular vessels and vascular beds
JF  - Journal of Glaucoma
Y1  - 2007
SN  - 2078-4104
VL  - Vol. 6
IS  - 1
SP  - 61
EP  - 68
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part II. Invasive methods of assessment of ocular blood flow
JF  - National Journal Glaucoma
Y1  - 2006
SN  - 2078-4104
VL  - Vol. 5
IS  - No. 4
SP  - 37
EP  - 49
ER  - 
TY  - JOUR
A1  - Hauser, C.
A1  - Kotliar, Konstantin
A1  - Tholen, S.
A1  - Hasenau, A.
A1  - Suttmann, Y.
A1  - Renders, L.
A1  - Heemann, U.
A1  - Baumann, M.
A1  - Schmaderer, C.
T1  - Dynamische retinale Gefäßreaktion bei Hämodialysepatienten
JF  - Nieren- und Hochdruckkrankheiten
Y1  - 2015
U6  - https://doi.org/10.5414/NHX01743a
SN  - 0300-5224
VL  - 44
IS  - 11
SP  - 480
EP  - 480
PB  - Dustri-Verlag
CY  - Oberhaching
ER  - 
TY  - JOUR
A1  - Pookhalil, Ali
A1  - Amoabediny, Ghassem
A1  - Tabesh, Hadi
A1  - Behbahani, Mehdi
A1  - Mottaghy, Khosrow
T1  - A new approach for semiempirical modeling of mechanical blood trauma
JF  - The international journal of artificial organs
N2  - Purpose
Two semi-empirical models were recently published, both making use of existing literature data, but each taking into account different physical phenomena that trigger hemolysis. In the first model, hemoglobin (Hb) release is described as a permeation procedure across the membrane, assuming a shear stress-dependent process (sublethal model). The second model only accounts for hemoglobin release that is caused by cell membrane breakdown, which occurs when red blood cells (RBC) undergo mechanically induced shearing for a period longer than the threshold time (nonuniform threshold model). In this paper, we introduce a model that considers the hemolysis generated by both these possible phenomena.
Methods
Since hemolysis can possibly be caused by permeation of hemoglobin through the RBC functional membrane as well as by release of hemoglobin from RBC membrane breakdown, our proposed model combines both these models. An experimental setup consisting of a Couette device was utilized for validation of our proposed model.
Results
A comparison is presented between the damage index (DI) predicted by the proposed model vs. the sublethal model vs. the nonthreshold model and experimental datasets. This comparison covers a wide range of shear stress for both human and porcine blood. An appropriate agreement between the measured DI and the DI predicted by the present model was obtained.
Conclusions
The semiempirical hemolysis model introduced in this paper aims for significantly enhanced conformity with experimental data. Two phenomenological outcomes become possible with the proposed approach: an estimation of the average time after which cell membrane breakdown occurs under the applied conditions, and a prediction of the ratio between the phenomena involved in hemolysis.
Y1  - 2016
U6  - https://doi.org/10.5301/ijao.5000474
SN  - 1724-6040
VL  - 39
IS  - 4
SP  - 171
EP  - 177
PB  - Sage
CY  - London
ER  - 
TY  - JOUR
A1  - Schoenrock, Britt
A1  - Muckelt, Paul E.
A1  - Hastermann, Maria
A1  - Albracht, Kirsten
A1  - MacGregor, Robert
A1  - Martin, David
A1  - Gunga, Hans-Christian
A1  - Salanova, Michele
A1  - Stokes, Maria J.
A1  - Warner, Martin B.
A1  - Blottner, Dieter
T1  - Muscle stiffness indicating mission crew health in space
JF  - Scientific Reports
N2  - Muscle function is compromised by gravitational unloading in space affecting overall musculoskeletal health. Astronauts perform daily exercise programmes to mitigate these effects but knowing which muscles to target would optimise effectiveness. Accurate inflight assessment to inform exercise programmes is critical due to lack of technologies suitable for spaceflight. Changes in mechanical properties indicate muscle health status and can be measured rapidly and non-invasively using novel technology. A hand-held MyotonPRO device enabled monitoring of muscle health for the first time in spaceflight (> 180 days). Greater/maintained stiffness indicated countermeasures were effective. Tissue stiffness was preserved in the majority of muscles (neck, shoulder, back, thigh) but Tibialis Anterior (foot lever muscle) stiffness decreased inflight vs. preflight (p < 0.0001; mean difference 149 N/m) in all 12 crewmembers. The calf muscles showed opposing effects, Gastrocnemius increasing in stiffness Soleus decreasing. Selective stiffness decrements indicate lack of preservation despite daily inflight countermeasures. This calls for more targeted exercises for lower leg muscles with vital roles as ankle joint stabilizers and in gait. Muscle stiffness is a digital biomarker for risk monitoring during future planetary explorations (Moon, Mars), for healthcare management in challenging environments or clinical disorders in people on Earth, to enable effective tailored exercise programmes.
KW  - Ageing
KW  - Anatomy
KW  - Muscle
KW  - Musculoskeletal system
KW  - Physiology
Y1  - 2024
U6  - https://doi.org/10.1038/s41598-024-54759-6
SN  - 2045-2322
N1  - Corresponding author: Dieter Blottner
VL  - 14
IS  - Article number: 4196
PB  - Springer Nature
CY  - London
ER  -