TY  - JOUR
A1  - Döring, Bernd
A1  - Feldmann, Markus
A1  - Kuhnhenne, Markus
A1  - Müller, Dirk
T1  - Phasenwechselmaterial im Metallleichtbau zur Optimierung von Energieeffizienz und sommerlicher Raumtemperatur
JF  - Stahlbau
Y1  - 2011
SN  - 1437-1049 (E-Journal); 0038-9145 (Print)
VL  - Vol. 80
IS  - Iss. 9
SP  - 666
EP  - 672
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Alt, Helmut
T1  - Die Sonne bestimmt zunehmend die Spannung in der Steckdose : Lastflussberechnung einer Photovoltaikeinspeisung
JF  - EW : das Magazin für die Energie-Wirtschaft
Y1  - 2011
SN  - 0013-5496
N1  - Printausg. in der Bibliothek vorhanden: 23 Z 585
VL  - Bd. 110
IS  - H. 17/18
SP  - 24
EP  - 29
PB  - VWEW-Energieverlag
CY  - Frankfurt, M.
ER  - 
TY  - JOUR
A1  - Kuperjans, Isabel
T1  - Gute Planung ist alles : Energieeffizienz in der Pharmaproduktion
JF  - Pharma + Food
Y1  - 2011
SN  - 1434-8942
VL  - 2011
IS  - 2
SP  - 8
EP  - 10
PB  - Hüthig
CY  - Heidelberg
ER  - 
TY  - JOUR
A1  - Niehaus, F.
A1  - Gabor, E.
A1  - Wieland, S.
A1  - Siegert, Petra
A1  - Maurer, Karl-Heinz
A1  - Eck, J.
T1  - Enzymes for the laundry industries: tapping the vast metagenomic pool of alkaline proteases
JF  - Microbial biotechnology
Y1  - 2011
SN  - 1432-0614 (E-Journal); 0171-1741 (Print); 0175-7598 (Print); 0340-2118 (Print)
VL  - Vol. 4
IS  - Iss. 6
SP  - 767
EP  - 776
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Ribitsch, D.
A1  - Heumann, S.
A1  - Trotscha, E.
A1  - Herrero Acero, E.
A1  - Greimel, K.
A1  - Leber, R.
A1  - Birger-Gruenberger, R.
A1  - Deller, S.
A1  - Eiteljoerg, I.
A1  - Remler, P.
A1  - Weber, Th.
A1  - Siegert, Petra
A1  - Maurer, Karl-Heinz
A1  - Donelli, I.
A1  - Freddi, G.
A1  - Schwab, H.
A1  - Guebitz, G. M.
T1  - Hydrolysis of polyethyleneterephthalate by p-nitrobenzylesterase from Bacillus subtilis
JF  - Biotechnology progress
Y1  - 2011
SN  - 1520-6033 (E-Journal); 8756-7938 (Print)
VL  - Vol. 27
IS  - Iss. 4
SP  - 951
EP  - 960
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Eilmann, Britta
A1  - Zweifel, Roman
A1  - Buchmann, Nina
A1  - Graf Pannatier, Elisabeth
A1  - Rigling, Andreas
T1  - Drought alters timing, quantity, and quality of wood formation in Scots pine
JF  - Journal of Experimental Botany
Y1  - 2011
U6  - http://dx.doi.org/10.1093/jxb/erq443
SN  - 1460-2431 (Online)
SN  - 0022-0957 (Print)
VL  - 62
IS  - 8
SP  - 2763
EP  - 2771
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Bragard, Michael
A1  - Conrad, M.
A1  - van Hoek, H.
A1  - De Doncker, R. W.
T1  - The integrated emitter turn-off thyristor (IETO) : an innovative thyristor-based high power semiconductor device using MOS assisted turn-off
JF  - IEEE transactions on industry applications
Y1  - 2011
U6  - http://dx.doi.org/10.1109/TIA.2011.2161432
SN  - 0093-9994
VL  - 47
IS  - 5
SP  - 2175
EP  - 2182
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Wagner, Torsten
A1  - Miyamoto, K.
A1  - Werner, Frederik
A1  - Schöning, Michael Josef
A1  - Yoshinobu, T.
T1  - Utilising Digital Micro-Mirror Device (DMD) as Scanning Light Source for Light-Addressable Potentiometric Sensors (LAPS)
Y1  - 2011
U6  - http://dx.doi.org/10.1166/sl.2011.1620
VL  - 9
IS  - 2
SP  - 812
EP  - 815
PB  - American Scientific Publishers
CY  - Stevenson Ranch, Calif.
ER  - 
TY  - JOUR
A1  - Siers, Carsten
A1  - Sögtrop, Christian
A1  - Borrmann, Arne
A1  - Hoepner, Gert
T1  - Vernetzung von Kultur und Struktur
JF  - Sales-Business : der Navigator für Vertrieb, Verkauf und Strategie
Y1  - 2011
U6  - http://dx.doi.org/10.1365/s35141-011-0093-5
SN  - 1616-7902
VL  - 20
IS  - 5
SP  - 32
EP  - 34
PB  - Springer Gabler
CY  - Wiesbaden
ER  - 
TY  - JOUR
A1  - Fuchs, Britta
A1  - Ritz, Thomas
T1  - Absatzkanäle kaum verknüpft
JF  - IT-Mittelstand : IT-Business im Mittelstand
Y1  - 2011
VL  - 2011
IS  - 9
SP  - 16
PB  - Medienhaus-Verlag
CY  - Bergisch-Gladbach
ER  - 
TY  - JOUR
A1  - Raab, Monika
A1  - Kappel, Sven
A1  - Krämer, Andrea
A1  - Sanhaji, Mourad
A1  - Matthess, Yves
A1  - Kurunci-Csacsko, Elisabeth
A1  - Calzada-Wack, Julia
A1  - Rathkolb, Birgit
A1  - Rosman, Jan
A1  - Adler, Thure
A1  - Busch, Dirk H.
A1  - Esposito, Irene
A1  - Fuchs, Helmut
A1  - Gailus-Durner, Valérie
A1  - Klingenspor, Martin
A1  - Wolf, Eckhard
A1  - Sänger, Nicole
A1  - Prinz, Florian
A1  - Hrabe de Angelis, Martin
A1  - Seibler, Jost
A1  - Yuan, Juping
A1  - Bergmann, Martin
A1  - Knecht, Rainald
A1  - Kreft, Bertolt
A1  - Strebhardt, Klaus
T1  - Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells
JF  - Nature Communications
Y1  - 2011
U6  - http://dx.doi.org/10.1038/ncomms1395
SN  - 2041-1723
VL  - 2
IS  - 395
SP  - 1
EP  - 11
PB  - Nature
CY  - London
ER  - 
TY  - JOUR
A1  - Hasegawa, Maki
A1  - Kapelyukh, Yury
A1  - Tahara, Harunobu
A1  - Seibler, Jost
A1  - Rode, Anja
A1  - Krueger, Sylvia
A1  - Lee, Dongtao N.
A1  - Wolf, C. Roland
A1  - Scheer, Nico
T1  - Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line
JF  - Molecular Pharmacology
Y1  - 2011
U6  - http://dx.doi.org/10.1124/mol.111.071845
SN  - 1521-0111
VL  - 80
IS  - 33
SP  - 518
EP  - 528
PB  - ASPET
CY  - Bethesda, Md.
ER  - 
TY  - JOUR
A1  - Jordan, Sabine D.
A1  - Krüger, Markus
A1  - Willmes, Diana M.
A1  - Redemann, Nora
A1  - Wunderlich, F. Thomas
A1  - Brönneke, Hella S.
A1  - Merkwirth, Carsten
A1  - Kashkar, Hamid
A1  - Olkkonen, Vesa M.
A1  - Böttger, Thomas
A1  - Braun, Thomas
A1  - Seibler, Jost
A1  - Brüning, Jens C.
T1  - Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
JF  - Nature Cell Biology
N2  - The contribution of altered post-transcriptional gene silencing to the development of insulin resistance and type 2 diabetes mellitus so far remains elusive. Here, we demonstrate that expression of microRNA (miR)-143 and 145 is upregulated in the liver of genetic and dietary mouse models of obesity. Induced transgenic overexpression of miR-143, but not miR-145, impairs insulin-stimulated AKT activation and glucose homeostasis. Conversely, mice deficient for the miR-143–145 cluster are protected from the development of obesity-associated insulin resistance. Quantitative-mass-spectrometry-based analysis of hepatic protein expression in miR-143-overexpressing mice revealed miR-143-dependent downregulation of oxysterol-binding-protein-related protein (ORP) 8. Reduced ORP8 expression in cultured liver cells impairs the ability of insulin to induce AKT activation, revealing an ORP8-dependent mechanism of AKT regulation. Our experiments provide direct evidence that dysregulated post-transcriptional gene silencing contributes to the development of obesity-induced insulin resistance, and characterize the miR-143–ORP8 pathway as a potential target for the treatment of obesity-associated diabetes.
Y1  - 2011
U6  - http://dx.doi.org/10.1038/ncb2211
SN  - 1465-7392
VL  - 13
IS  - 4
SP  - 434
EP  - 446
PB  - Nature
CY  - New York
ER  - 
TY  - JOUR
A1  - Inagaki, Akiko
A1  - Sleddens-Linkels, Esther
A1  - Wassenaar, Evelyne
A1  - Ooms, Marja
A1  - Cappellen, Wiggert A. van
A1  - Hoeijmakers, Jan H. J.
A1  - Seibler, Jost
A1  - Vogt, Thomas F.
A1  - Shin, Myung K.
A1  - Grootegoed, J. Anton
A1  - Baarends, Willy M.
T1  - Meiotic functions of RAD18
JF  - Journal of Cell Science
Y1  - 2011
U6  - http://dx.doi.org/10.1242/jcs.081968
SN  - 1477-9137
VL  - 124
IS  - 16
SP  - 2837
EP  - 2850
PB  - Company of Biologists Limited
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Fissabre, Anke
T1  - Dachterrassen der Renaissance – „Cosa più maravigliosa che gl’orti pensili di Babbilonia“
JF  - Architectura : Zeitschrift für Geschichte der Baukunst
Y1  - 2011
SN  - 0044-863X
VL  - 41
IS  - 1
SP  - 27
EP  - 46
PB  - De Gruyter
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Mottaghy, Darius
A1  - Pechnig, Renate
A1  - Vogt, Christian
T1  - The geothermal project Den Haag: 3D numerical models for temperature prediction and reservoir simulation
JF  - Geothermics
N2  - The proposed Den Haag Zuidwest district heating system of the city of The Hague consists of a deep doublet in a Jurassic sandstone layer that is designed for a production temperature of 75 °C and a reinjection temperature of 40 °C at a flow rate of 150 m3 h−1. The prediction of reservoir temperature and production behavior is crucial for success of the proposed geothermal doublet. This work presents the results of a study of the important geothermal and geohydrological issues for the doublet design. In the first phase of the study, the influences of the three-dimensional (3D) structures of anticlines and synclines on the temperature field were examined. A comprehensive petrophysical investigation was performed to build a large scale 3D-model of the reservoir. Several bottomhole temperatures (BHTs), as well as petrophysical logs were used to calibrate the model using thermal conductivity measurements on 50 samples from boreholes in different lithological units in the study area. Profiles and cross sections extracted from the calculated temperature field were used to study the temperature in the surrounding areas of the planned doublet. In the second phase of the project, a detailed 3D numerical reservoir model was set up, with the aim of predicting the evolution of the producer and injector temperatures, and the extent of the cooled area around the injector. The temperature model from the first phase provided the boundary conditions for the reservoir model. Hydraulic parameters for the target horizons, such as porosity and permeability, were taken from data available from the nearby exploration wells. The simulation results are encouraging as no significant thermal breakthrough is predicted. For the originally planned location of the producer, the extracted water temperature is predicted to be around 79 °C, with an almost negligible cooling in the first 50 years of production. When the producer is located shallower parts of the reservoir, the yield water temperatures is lower, starting at ≈76 °C and decreasing to ≈74 °C after 50 years of operation. This comparatively larger decrease in temperature with time is caused by the structural feature of the reservoir, namely a higher dip causes the cooler water to easily move downward. In view of the poor reservoir data, the reservoir simulation model is constructed to allow iterative updates using data assimilation during planned drilling, testing, and production phases. Measurements during an 8 h pumping test carried out in late 2010 suggest that a flow rate of 150 m3 h−1 is achievable. Fluid temperatures of 76.5 °C were measured, which is very close to the predicted value.
Y1  - 2011
U6  - http://dx.doi.org/10.1016/j.geothermics.2011.07.001
SN  - 0375-6505
VL  - 40
IS  - 3
SP  - 199
EP  - 210
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Lind, Thorsten Patric
T1  - Handelndenhaftung bei Vorrats- oder Mantel-GmbH nur für vor Offenlegung der wirtschaftlichen Neugründung ohne Zustimmung aller Gesellschafter vorgenommene Geschäfte : BGH, Urteil vom 12.07.2011 - II ZR 71/11 : Anmerkung
JF  - Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-Möhring
Y1  - 2011
SN  - 1611-1095
IS  - 11
PB  - Beck
CY  - München
ER  - 
TY  - JOUR
A1  - Lind, Thorsten Patric
T1  - Keine Beseitigung der Zahlungsunfähigkeit und ihrer Kenntnis durch Patronatserklärung : BGH, Urteil vom 19.05.2011 - IX ZR 9/10 : Anmerkung
JF  - Fachdienst Zivilrecht - LMK - Kommentierte BGH-Rechtsprechung, Lindenmaier-Möhring
Y1  - 2011
SN  - 1611-1095
IS  - Ausg. 8
SP  - 320922
PB  - Beck
CY  - München
ER  - 
TY  - JOUR
A1  - Hage, Ralf
A1  - Lind, Thorsten Patric
T1  - Zur Qualifizierung der von dem Aussonderungsberechtigten aufgewandten Ausbaukosten als Masseverbindlichkeiten
JF  - Zeitschrift für das gesamte Insolvenzrecht : ZInsO
Y1  - 2011
SN  - 1615-8032
IS  - 50
SP  - 2264
EP  - 2268
PB  - Carl Heymanns Verlag
CY  - Köln
ER  - 
TY  - JOUR
A1  - Norda, Hannah
A1  - Butenweg, Christoph
T1  - Möglichkeiten und Grenzen der Anwendbarkeit statisch nichtlinearer Verfahren nach DIN EN 1998-1
JF  - Bauingenieur : die richtungsweisende Zeitschrift im Bauingenieurswesen ; offizielle Zeitschrift der VDI-Gesellschaft Bautechnik. Beilage: D-A-CH-Mitteilungsblatt
Y1  - 2011
SN  - 1436-4867 (E-Journal); 0005-6650 (Print)
N1  - Printausgabe in der Bibliothek Bayernallee vorhanden: 13 Z 049-2011
VL  - Band 86
SP  - S13
EP  - S21
PB  - VDI Fachmedien
CY  - Düsseldorf
ER  -