TY  - CHAP
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Sherelkhan, Dinara K.
A1  - Razzaque, Mohammed S.
T1  - Vitamin D and Phosphate Interactions in Health and Disease
T2  - Phosphate Metabolism
N2  - Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.
KW  - Vitamin D
KW  - PTH
KW  - Phosphate
KW  - FGF23
KW  - Klotho
Y1  - 2022
SN  - 978-3-030-91621-3
U6  - https://doi.org/10.1007/978-3-030-91623-7_5
SP  - 37
EP  - 46
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Sherelkhan, Dinara K.
A1  - Lutfor, Afzalunnessa B.
A1  - Razzaque, Mohammed S.
T1  - Vitamin D and the Host-Gut Microbiome: A Brief Overview
JF  - Acta Histochemica et Cytochemica
N2  - There is a growing body of evidence for the effects of vitamin D on intestinal host-microbiome interactions related to gut dysbiosis and bowel inflammation. This brief review highlights the potential links between vitamin D and gut health, emphasizing the role of vitamin D in microbiological and immunological mechanisms of inflammatory bowel diseases. A comprehensive literature search was carried out in PubMed and Google Scholar using combinations of keywords “vitamin D,” “intestines,” “gut microflora,” “bowel inflammation”. Only articles published in English and related to the study topic are included in the review. We discuss how vitamin D (a) modulates intestinal microbiome function, (b) controls antimicrobial peptide expression, and (c) has a protective effect on epithelial barriers in the gut mucosa. Vitamin D and its nuclear receptor (VDR) regulate intestinal barrier integrity, and control innate and adaptive immunity in the gut. Metabolites from the gut microbiota may also regulate expression of VDR, while vitamin D may influence the gut microbiota and exert anti-inflammatory and immune-modulating effects. The underlying mechanism of vitamin D in the pathogenesis of bowel diseases is not fully understood, but maintaining an optimal vitamin D status appears to be beneficial for gut health. Future studies will shed light on the molecular mechanisms through which vitamin D and VDR interactions affect intestinal mucosal immunity, pathogen invasion, symbiont colonization, and antimicrobial peptide expression.
Y1  - 2020
U6  - https://doi.org/10.1267/ahc.20011
SN  - 1347-5800
VL  - 53
IS  - 3
SP  - 33
EP  - 42
PB  - Japan Society of Histochemistry and Cytochemistry
CY  - Osaka
ER  - 
TY  - JOUR
A1  - Emons, H.
A1  - Baade, A.
A1  - Schöning, Michael Josef
T1  - Voltammetric determination of heavy metals in microvolumes of rain water
JF  - Electroanalysis. 12 (2000), H. 15
Y1  - 2000
SN  - 1040-0397
SP  - 1171
EP  - 1176
ER  - 
TY  - JOUR
A1  - Emons, H.
A1  - Glück, O.
A1  - Hüllenkremer, B.
A1  - Schöning, Michael Josef
T1  - Voltohmmetry as an alternative detection method at polycrystalline metal film electrodes
JF  - Electroanalysis. 13 (2001), H. 8-9
Y1  - 2001
SN  - 1040-0397
SP  - 677
EP  - 680
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Hüllenkremer, B.
A1  - Glück, O.
A1  - Lüth, H.
A1  - Emons, H.
T1  - Voltohmmetry – a novel sensing principle for heavy metal determination in aqueous solutions
JF  - Sensors and Actuators B. 78 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 275
EP  - 280
ER  - 
TY  - JOUR
A1  - Emons, H.
A1  - Glück, O.
A1  - Schöning, Michael Josef
T1  - Voltohmmetry – An alternative detection principle at ultrathin metal electrodes in solution
JF  - Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler
Y1  - 2001
SN  - 1-56677-351-2
N1  - International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.)
SP  - 1
EP  - 3
PB  - Electrochemical Society
CY  - Pennington, NJ
ER  - 
TY  - CHAP
A1  - Karimi, Iman
A1  - Butenweg, Christoph
A1  - Toll, Britta
T1  - Vulnerability assessment of industrial facilities
T2  - Proceedings of the Tenth International Conference on Civil, Structural and Environmental Engineering Computing : [Rome, Italy, 30. August - 2. September 2005] / ed. by B. H. V. Topping
Y1  - 2005
SN  - 1-905088-00-0
U6  - https://doi.org/10.4203/ccp.81.34
SP  - 34, 73
EP  - 75
PB  - Civil-Comp Press
CY  - Stirling
ER  - 
TY  - CHAP
A1  - Pfaff, Raphael
A1  - Schmidt, Bernd
A1  - Wilbring, Daniela
A1  - Franzen, Julian
T1  - Wagon4.0 – the smart wagon for improved integration into Industry 4.0 plants
T2  - Proceedings of the International Heavy Haul Association STS Conference 2019
N2  - In many instances, freight vehicles exchange load or information with plants that are or will soon be Industry4.0 plants. The Wagon4.0 concept, as developed in close cooperation with e.g. port or mine operations, offers a maximum in railway operational efficiency while providing strong business cases already in the respective plant interaction. The Wagon4.0 consists of main components, a power supply, data network, sensors, actuators and an operating system, the so called WagonOS. The Wagon OS is implemented in a granular, self-sufficient manner, to allow basic features such as WiFi-Mesh and train christening in remote areas without network connection. Furthermore, the granularity of the operating system allows to extend the familiar app concept to freight rail rolling stock, making it possible to use specialised actuators for certain applications, e.g. an electrical parking brake or an auxiliary drive. In order to facilitate migration to the Wagon4.0 for existing fleets, a migration concept featuring five levels of technical adaptation was developed. The present paper investigates the benefits of Wagon4.0-implementations for the particular challenges of heavy haul operations by focusing on train christening, ep-assisted braking, autonomous last mile and traction boost operation as well as improved maintenance schedules
Y1  - 2019
N1  - International Heavy Haul Association STS Conference, 10th to 14th June 2019, Narvik, Norway
ER  - 
TY  - JOUR
A1  - Schirra, Julian
A1  - Bissonnette, William
A1  - Bramesfeld, Götz
T1  - Wake-model effects on induced drag prediction of staggered boxwings
JF  - Aerospace
Y1  - 2018
U6  - https://doi.org/10.3390/aerospace5010014
SN  - 2226-4310
VL  - 5
IS  - 1
ER  - 
TY  - JOUR
A1  - Meliß, Michael
A1  - Neskakis, A.
A1  - Plettner-Marliani, J.
A1  - Lange, C.
A1  - Hövelmann, A.
A1  - Schumacher, J.
T1  - Waste water recycling supplied by renewable energies : basic conditions and possible treatment technologies
JF  - Renewable energy. Vol. 14 (1998), iss. 1-4. 6th Arab International Solar Energy Conference: Bringing Solar Energy into the Daylight, Muscat, Sultanate of Oman, 29.03.-01.04.1998
Y1  - 1998
SN  - 1879-0682 (E-Book); 0960-1481 (Print)
SP  - 325
EP  - 331
ER  - 
TY  - CHAP
A1  - Bung, Daniel Bernhard
A1  - Oertel, Mario
T1  - Wave breaking over a submerged horizontal plate: Optical Flow, LES and RANS
T2  - E-proceedings of the 38th IAHR World Congress  September 1-6, 2019, Panama City, Panama
Y1  - 2019
U6  - https://doi.org/10.3850/38WC092019-0509
SP  - 3690
EP  - 3698
ER  - 
TY  - JOUR
A1  - Staat, Manfred
A1  - Ballmann, J.
T1  - Wave Propagation and Focussing in Plates
JF  - Impact loading and dynamic behaviour of materials : Papers presented at the International Conference on Impact Loading and Dynamic Behaviour of Materials, Vol. 2 /  Chiem, C. Y.; Kunze, L. (u.a.) [eds]
Y1  - 1988
PB  - DGM Informationsges.
CY  - Oberursel
ER  - 
TY  - JOUR
A1  - Hartung, Frank
A1  - Husoy, J. H.
T1  - Wavelet and subband coding of images - A comparative study / Hartung, F. ; Husoy, J. H.
JF  - Mathematical imaging: wavelet applications in signal and image processing : 15 - 16 July 1993, San Diego, California / sponsored and publ. by SPIE - the International Society for Optical Engineering. Andrew F. Laine, chair/ed
Y1  - 1993
SN  - 081941283X
N1  - SPIE proceedings series ; 2034 ; Society of Photo-Optical Instrumentation Engineers ; Conference ; (1993.07.15-16 : ; San Diego, Calif.)
SP  - 242
EP  - 253
PB  - SPIE
CY  - Bellingham, Wash.
ER  - 
TY  - JOUR
A1  - Müller-Veggian, Mattea
A1  - Haenni, D. R.
A1  - Beuscher, H.
A1  - Lieder, R. M.
T1  - Weak coupling and high-spin states in ¹⁴⁵ Eu
JF  - Nuclear physics / A. 331 (1979), H. 1
Y1  - 1979
SN  - 0375-9474
SP  - 141
EP  - 154
ER  - 
TY  - CHAP
A1  - Müller-Veggian, Mattea
A1  - Haenni, D. R.
A1  - Beuscher, H.
A1  - Lieder, R. M.
T1  - Weak coupling of a neutron hole to a ¹⁴⁶ Gd core ; an in-beam study of ¹⁴⁵ Gd
T2  - Structure of medium-heavy nuclei, 1979 : proceedings of the 6. European Physical Soc. Nuclear Divisional Conference on the Structure of Medium-Heavy Nuclei held in Rhodes, Greece, 1-4 May 1979 / ed. Committee: G. S. Anagnostatos ... - (Conference series / Institute of Physics London, Bristol ; 49)
Y1  - 1980
SN  - 0-85498-140-3
N1  - Conference on the Structure of Medium Heavy Nuclei <6, 1979, Rodos> ; European Physical Society / Nuclear Physics Division
SP  - 133
PB  - Inst. of Physics
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Dikta, Gerhard
T1  - Weak Representation of the Cumulative Hazard Function under Semiparametric Random Censorship Models
JF  - Statistics. 35 (2001), H. 4
Y1  - 2001
SN  - 0233-1888
SP  - 395
EP  - 410
ER  - 
TY  - JOUR
A1  - Pawelke, Siegfried
T1  - Weak smoothness conditions for the uniform convergence of Fourier-Jacobi series
JF  - Functiones et Approximatio. Commentarii Mathematici. 9 (1980)
Y1  - 1980
SN  - 0208-6573
N1  - Zentralblatt MATH:  http://www.emis.de/MATH-item?0471.42018
SP  - 9
EP  - 13
ER  - 
TY  - JOUR
A1  - Schmitz, Günter
A1  - Schmitt, H.J.
A1  - Dammann, H.
T1  - Weakly Guiding Semileaky Isolator with a Form-Birefringent Top Layer
JF  - Conference on Lasers and Electro-Optics ; (5, 1985, Baltimore, Md.) ; Conference on Lasers and Electro-Optics (CLEO '85) ; (1985.05.21-24 ; Baltimore, Md.)
Y1  - 1985
SP  - 260
PB  - Optical Society of America
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Malzahn, Kerstin
A1  - Windmiller, Joshua Ray
A1  - Valdés-Ramírez, Gabriela
A1  - Wang, Joseph
A1  - Schöning, Michael Josef
T1  - Wearable electrochemical sensors for in situ analysis in marine environments
JF  - Analyst. 136 (2011), H. 14
Y1  - 2011
SN  - 0003-2654
SP  - 2912
EP  - 2917
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - CHAP
A1  - Hellmanns, Mark
A1  - Böhm, Stefan
A1  - Dilger, Klaus
T1  - Weight and noise reduction in power transmissions through epoxy resin foams
T2  - Proceedings of the 31st annual meeting of the Adhesion Society : 17. - 20.2.2008, Austin, Texas
Y1  - 2008
SP  - 291
EP  - 293
PB  - Adhesion Society
CY  - Blacksburg
ER  -