TY - JOUR A1 - Wu, Chunsheng A1 - Bronder, Thomas A1 - Poghossian, Arshak A1 - Werner, Frederik A1 - Bäcker, Matthias A1 - Schöning, Michael Josef T1 - Label-free electrical detection of DNA with a multi-spot LAPS: First step towards light-addressable DNA chips JF - Physica status solidi A : Applications and materials science N2 - A multi-spot (4 × 4 spots) light-addressable potentiometric sensor (MLAPS) consisting of an Al–p-Si–SiO2 structure has been applied for the label-free electrical detection of DNA (deoxyribonucleic acid) immobilization and hybridization by the intrinsic molecular charge for the first time. Single-stranded probe ssDNA molecules (20 bases) were covalently immobilized onto the silanized SiO2 gate surface. The unspecific adsorption of mismatch ssDNA on the MLAPS gate surface was blocked by bovine serum albumin molecules. To reduce the screening effect and to achieve a high sensor signal, the measurements were performed in a low ionic-strength solution. The photocurrent–voltage (I–V) curves were simultaneously recorded on all 16 spots after each surface functionalization step. Large shifts of I–V curves of 25 mV were registered after the DNA immobilization and hybridization event. In contrast, a small potential shift (∼5 mV) was observed in case of mismatch ssDNA, revealing good specificity of the sensor. The obtained results demonstrate the potential of the MLAPS as promising transducer platform for the multi-spot label-free electrical detection of DNA molecules by their intrinsic molecular charge. Y1 - 2014 U6 - https://doi.org/10.1002/pssa.201330442 SN - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print) VL - 211 IS - 6 SP - 1423 EP - 1428 PB - Wiley-VCH CY - Weinheim ER - TY - CHAP A1 - Anthrakidis, Anette A1 - Herrmann, Ulf A1 - Schorn, Christian A1 - Schwarzer, Klemens A1 - Wedding, Philipp A1 - Weis, Fabian T1 - Development and Testing of a Novel Method for the Determination of the Efficiency of Concentrating Solar Thermal Collectors T2 - Conference Proceedings Solar World Congress 2015, Daegu, Korea, 08 – 12 November 2015 Y1 - 2015 ER - TY - JOUR A1 - Ferrein, Alexander A1 - Fritz, Christian A1 - Lakemeyer, Gerhard T1 - On-Line Decision-Theoretic Golog for Unpredictable Domains / Ferrein, Alexander ; Fritz, Christian ; Lakemeyer, Gerhard JF - KI 2004: Advances in Artificial Intelligence : 27th Annual German Conference on AI, KI 2004, Ulm, Germany, September 20-24, 2004. Proceedings Y1 - 2004 N1 - Lecture Notes in Computer Science ; 3238 SP - 322 EP - 336 PB - Springer CY - Berlin ER - TY - CHAP A1 - Näther, Niko A1 - Poghossian, Arshak A1 - Platen, J. A1 - Yoshinobu, T. A1 - Koudelka-Hep, M. A1 - Schöning, Michael Josef T1 - Multi-parameter sensing of both physical and (bio-)chemical quantities using the same transducer principle T2 - Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ... Y1 - 2006 SP - 172 EP - 181 CY - Warsaw ER - TY - JOUR A1 - Staat, Manfred A1 - Heitzer, M. T1 - Traglastanalyse - ein strukturmechanisches Verfahren zur Beurteilung von gerissenen Bauteilen und Verbindungen JF - Festigkeits- und Bruchverhalten von Fügeverbindungen : 32. Tagung des DVM-Arbeitskreises Bruchvorgänge ; 22. und 23. Februar 2000 in Berlin / Richard, H. A. [Hrsg] Y1 - 2000 N1 - DVM-Bericht 232 SP - 183 EP - 192 PB - Deutscher Verband für Materialforschung und -prüfung CY - Berlin ER - TY - JOUR A1 - Laack, Walter van A1 - Casser, H.-R. T1 - Arthroskopische Behandlung der Osteochondrosis dissecans an der medialen Femurrolle JF - Arthroskopie. 2 (1989), H. 1 Y1 - 1989 SN - 0933-7946 SP - 16 EP - 18 ER - TY - JOUR A1 - Poghossian, Arshak A1 - Jablonski, Melanie A1 - Molinnus, Denise A1 - Wege, Christina A1 - Schöning, Michael Josef T1 - Field-Effect Sensors for Virus Detection: From Ebola to SARS-CoV-2 and Plant Viral Enhancers JF - Frontiers in Plant Science N2 - Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases. Y1 - 2020 U6 - https://doi.org/10.3389/fpls.2020.598103 VL - 11 IS - Article 598103 SP - 1 EP - 14 PB - Frontiers CY - Lausanne ER - TY - JOUR A1 - Bialonski, Stephan A1 - Horstmann, Marie-Therese A1 - Lehnertz, Klaus T1 - From brain to earth and climate systems: Small-world interaction networks or not? JF - Chaos: An Interdisciplinary Journal of Nonlinear Science N2 - We consider recent reports on small-world topologies of interaction networks derived from the dynamics of spatially extended systems that are investigated in diverse scientific fields such as neurosciences, geophysics, or meteorology. With numerical simulations that mimic typical experimental situations, we have identified an important constraint when characterizing such networks: indications of a small-world topology can be expected solely due to the spatial sampling of the system along with the commonly used time series analysis based approaches to network characterization. Y1 - 2010 U6 - https://doi.org/10.1063/1.3360561 SN - 1089-7682 VL - 20 IS - 1 PB - AIP Publishing CY - Melville, NY ER - TY - CHAP A1 - Golland, Alexander A1 - Schneidereit, Peter ED - Borges, Georg ED - Werners, Brigitte T1 - Rechtliche Rahmenbedingungen des Identitätsmangements im Cloud Computing T2 - Identitätsmanagement Im Cloud Computing : Evaluation ökonomischer und Rechtlicher Rahmenbedingungen N2 - Cloud Computing wirft in zahlreichen Rechtsbereichen neuartige juristische Fragestellungen auf. Ziel der Darstellung der rechtlichen Rahmenbedingungen ist, die das Identitätsmanagement in der Cloud betreffenden Rechtsgrundlagen aus den unterschiedlichen Rechtsgebieten vorzustellen und einzuordnen, bevor im Rahmen des sechsten Kapitels die Darstellung der hieraus resultierenden Verpflichtungen in ihrer konkreten Form erfolgt. KW - Technische Schutzmaßnahmen KW - Identitätsmanagement KW - IT-Sicherheit KW - Cloud Computing KW - Datenschutz Y1 - 2018 SN - 978-3-662-55584-2 U6 - https://doi.org/10.1007/978-3-662-55584-2_4 SP - 53 EP - 104 PB - Springer CY - Berlin ER - TY - JOUR A1 - Laack, Walter van A1 - Hennes, A. A1 - Refisch, A. T1 - Narkosemobilisation der Schultersteife (Periarthritis humeroscapularis ankylosans) JF - Zeitschrift für Orthopädie und Ihre Grenzgebiete. 125 (1987), H. 6 Y1 - 1987 SN - 0044-3220 SP - 669 EP - 673 ER - TY - JOUR A1 - Heuermann, Holger T1 - Selbstkalibrierverfahren zur Systemfehlerkorrektur von Streuparametermessungen auf Halbleitersubstraten JF - Mikrowellen und Optronik : Kongreßunterlagen = Microwaves and optronics / MIOP '95, 8. Kongreßmesse für Hochfrequenztechnik, Messehalle Sindelfingen, 30. Mai - 1. Juni 1995. [Hrsg.: Network GmbH] Y1 - 1995 SN - 3-924651-45-0 N1 - MIOP ; (8, 1995, Sindelfingen) SP - 23 EP - 29 CY - Hagenburg ER - TY - JOUR A1 - Heuermann, Holger A1 - Graf, W. T1 - Vergleich mehrerer Naeherungsverfahren zur Berechnung des Wellenwiderstandes von Mikrostreifenleitungen mit experimentellen Ergebnissen JF - Kleinheubacher Berichte : Vorträge und Berichte der gemeinsamen Tagung des U.R.S.I.-Landesausschusses in der Bundesrepublik Deutschland / Hrsg.: Deutsche Telekom AG. 39. 1996 (1996) Y1 - 1996 ER - TY - JOUR A1 - Heuermann, Holger A1 - Schiek, Burkhard T1 - Sichere on-wafer-Streuparameter-Messungen mit Selbstkalibrierverfahren JF - Kleinheubacher Berichte : Vorträge und Berichte der gemeinsamen Tagung des U.R.S.I.-Landesausschusses in der Bundesrepublik Deutschland / Hrsg.: Deutsche Telekom AG. 38. 1994 (1994) Y1 - 1994 SP - 611 EP - 622 ER - TY - CHAP A1 - Lohse, Wolfram A1 - Stroetmann, Richard ED - Vismann, Ulrich T1 - Stahlbau T2 - Wendehorst Bautechnische Zahlentafeln Y1 - 2012 SN - 978-3-8348-0960-5 U6 - https://doi.org/10.1007/978-3-8348-8613-2_13 N1 - Kapitel 13 SP - 777 EP - 1019 PB - Vieweg + Teubner CY - Wiesbaden ET - 34 ER - TY - JOUR A1 - Weigand, Christoph T1 - Economically Optimal Adaptive Inspection Policies JF - Economic Quality Control. 15 (2000), H. 1/2 Y1 - 2000 SN - 0940-5151 N1 - Printausgabe vorhanden: 43 Z 711 SP - 55 EP - 77 ER - TY - CHAP A1 - Alhwarin, Faraj A1 - Ferrein, Alexander A1 - Scholl, Ingrid T1 - IR stereo kinect: improving depth images by combining structured light with IR stereo T2 - PRICAI 2014: Trends in artificial intelligence : 13th Pacific Rim International Conference on Artificial Intelligence : Gold Coast, QLD, Australia, December 1-5, 2014 : proceedings. (Lecture notes in computer science ; vol. 8862) N2 - RGB-D sensors such as the Microsoft Kinect or the Asus Xtion are inexpensive 3D sensors. A depth image is computed by calculating the distortion of a known infrared light (IR) pattern which is projected into the scene. While these sensors are great devices they have some limitations. The distance they can measure is limited and they suffer from reflection problems on transparent, shiny, or very matte and absorbing objects. If more than one RGB-D camera is used the IR patterns interfere with each other. This results in a massive loss of depth information. In this paper, we present a simple and powerful method to overcome these problems. We propose a stereo RGB-D camera system which uses the pros of RGB-D cameras and combine them with the pros of stereo camera systems. The idea is to utilize the IR images of each two sensors as a stereo pair to generate a depth map. The IR patterns emitted by IR projectors are exploited here to enhance the dense stereo matching even if the observed objects or surfaces are texture-less or transparent. The resulting disparity map is then fused with the depth map offered by the RGB-D sensor to fill the regions and the holes that appear because of interference, or due to transparent or reflective objects. Our results show that the density of depth information is increased especially for transparent, shiny or matte objects. Y1 - 2014 SN - 978-3-319-13559-5 (Print) ; 978-3-319-13560-1 (E-Book) U6 - https://doi.org/10.1007/978-3-319-13560-1_33 SP - 409 EP - 421 PB - Springer CY - München ER - TY - CHAP A1 - Bung, Daniel Bernhard A1 - Langohr, Phillip A1 - Waldenberger, Lisa ED - Habersack, Helmut ED - Tritthart, Michael T1 - Influence of cycle number in CFD studies of labyrinth weirs T2 - Proceedings of the 40th IAHR World Congress (Vienna, 2023) N2 - The major advantage of labyrinth weirs over linear weirs is hydraulic efficiency. In hydraulic modeling efforts, this strength contrasts with limited pump capacity as well as limited computational power for CFD simulations. For the latter, reducing the number of investigated cycles can significantly reduce necessary computational time. In this study, a labyrinth weir with different cycle numbers was investigated. The simulations were conducted in FLOW-3D HYDRO as a Large Eddy Simulation. With a mean deviation of 1.75 % between simulated discharge coefficients and literature design equations, a reasonable agreement was found. For downstream conditions, overall consistent results were observed as well. However, the orientation of labyrinth weirs with a single cycle should be chosen carefully under consideration of the individual research purpose. KW - CFD KW - Large Eddy Simulation KW - Labyfrinth weirs Y1 - 2023 SN - 978-90-833476-1-5 U6 - https://doi.org/10.3850/978-90-833476-1-5_iahr40wc-p0531-cd SN - L 2521-7119 (online) N1 - Vienna, Austria, from August 21 to 25, 2023 PB - International Association for Hydro-Environment Engineering and Research (IAHR) CY - Madrid ER - TY - JOUR A1 - Thiel, Alexander A1 - Muffler, Kai A1 - Tippkötter, Nils A1 - Suck, Kirstin A1 - Sohling, Ulrich A1 - Ruf, Friedrich A1 - Ulber, Roland T1 - Aufarbeitung von Polyphenolen aus Weizen mittels Zeolithen am Beispiel der Ferulasäure JF - Chemie IngenieurTechnik N2 - Aufarbeitung von Polyphenolen aus Weizenmittels Zeolithen am Beispiel der Ferulasa¨ ureAlexander Thiel1, Kai Muffler1, Nils Tippko¨ tter1, Kirstin Suck2, Ulrich Sohling2, Friedrich Ruf3und Roland Ulber1,*DOI: 10.1002/cite.201400031Bei der Ferulasa¨ure handelt es sich um einen Wertstoff, der aus Weizen gewonnen und in der Lebensmittel- und Pharma-industrie eingesetzt werden kann. Der Einsatz von Weizen als nachwachsende Rohstoffquelle ist allerdings nur dann wirt-schaftlich durchfu¨hrbar, wenn eine Prozessintegration in die bestehenden industriellen Verfahren gewa¨hrleistet oder einedirekte Konkurrenz zur Mehl- und Sta¨rkeindustrie vermieden werden kann. In diesem Artikel wird ein Verfahren aufge-zeigt, welches hohe Ausbeuten ermo¨glicht und eine Konkurrenz zu bestehenden Verwertungspfaden vermeidet. Y1 - 2015 U6 - https://doi.org/10.1002/cite.201400031 N1 - Englischer Titel: Downstream Processing of Polyphenols from Wheat by Zeolites using the Example of Ferulic Acid VL - 87 IS - 1-2 SP - 128 EP - 136 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Al-Kaidy, Huschyar A1 - Duwe, Anna A1 - Huster, Manuel A1 - Muffler, Kai A1 - Schlegel, Christin A1 - Tim, Sieker A1 - Stadtmüller, Ralf A1 - Tippkötter, Nils A1 - Ulber, Roland T1 - Biotechnology and bioprocess engineering – from the first ullmann's article to recent trends JF - ChemBioEng Reviews N2 - For several thousand years, biotechnology and its associated technical processes have had a great impact on the development of mankind. Based on empirical methods, in particular for the production of foodstuffs and daily commodities, these disciplines have become one of the most innovative future issues. Due to the increasing detailed understanding of cellular processes, production strains can now be optimized. In combination with modern bioprocesses, a variety of bulk and fine chemicals as well as pharmaceuticals can be produced efficiently. In this article, some of the current trends in biotechnology are discussed. Y1 - 2015 U6 - https://doi.org/10.1002/cben.201500008 VL - 2 IS - 3 SP - 175 EP - 184 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Schindler, Kaspar A. A1 - Bialonski, Stephan A1 - Horstmann, Marie-Therese A1 - Elger, Christian E. A1 - Lehnertz, Klaus T1 - Evolving functional network properties and synchronizability during human epileptic seizures JF - Chaos: An Interdisciplinary Journal of Nonlinear Science Y1 - 2008 U6 - https://doi.org/10.1063/1.2966112 SN - 1089-7682 VL - 18 IS - 3 SP - 033119 ER -