TY  - BOOK
A1  - Lauth, Jakob
T1  - Physikalische Chemie, 2: Chemische Thermodynamik
Y1  - 2016
SN  - 978-3-662-47621-5
PB  - Springer
CY  - Berlin
ER  - 
TY  - BOOK
A1  - Lauth, Jakob
T1  - Physikalische Chemie, 3: Phasengleichgewichte
Y1  - 2016
SN  - 978-3-662-47571-3
PB  - Springer
CY  - Berlin
ER  - 
TY  - BOOK
A1  - Lauth, Jakob
T1  - Physikalische Chemie, 4: Reaktionskinetik
Y1  - 2016
SN  - 978-3-662-47674-1
PB  - Springer
CY  - Berlin
ER  - 
TY  - BOOK
A1  - Lauth, Jakob
T1  - Physikalische Chemie, 5: Elektrochemie
Y1  - 2016
SN  - 978-3-662-47559-1
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Smith, Walker O.
A1  - Baumann, Marcus
A1  - Wilson, David L.
A1  - Aletsee, Ludwig
T1  - Phytoplankton biomass and productivity in the marginal ice zone of the Fram Strait during summer 1984
JF  - Journal of geophysical research
Y1  - 1987
SN  - 2156-2202 (E-Journal); 2169-9291 (E-Journal); 0148-0227 (Print); 2169-9275 (Print)
VL  - Vol. 92
IS  - Iss. C7
SP  - 6777
EP  - 6786
ER  - 
TY  - JOUR
A1  - Baumann, Marcus
A1  - Goeyens, L.
A1  - Semeneh, M.
A1  - Elskens, M.
T1  - Phytoplankton nutrient utilisation and nutrient signature in the Southern Ocean / Goeyens, L. ; Semeneh, M. ; Baumann, M.E.M. ; Elskens, M. ; Shopova, D. ; Dehairs, F.
JF  - Journal of Marine Systems. 17 (1998), H. 1-4
Y1  - 1998
SN  - 0924-7963
SP  - 143
EP  - 157
ER  - 
TY  - JOUR
A1  - Biselli, Manfred
A1  - Zeng, Steffen
A1  - Dinter, Andre
A1  - Eisenkrätzer, Detlef
T1  - Pilot Scale Expression and Purification of Soluble Protein A Tagged β1,6N-Acetylglucosaminyltransferase in CHO Cells / Zeng, Steffen ; Dinter, Andre ; Eisenkrätzer, Detlef ; Biselli, Manfred ; Wandrey, Christian ; Berger, Eric G.
JF  - Biochemical and Biophysical Research Communications. 237 (1997), H. 3
Y1  - 1997
SN  - 0006-291X
SP  - 653
EP  - 658
ER  - 
TY  - JOUR
A1  - Elbers, Gereon
A1  - Pfeffer, H.-U.
A1  - Friesel, J.
A1  - Beier, R.
T1  - Pilotuntersuchungen gemäß dem Verordnungsentwurf nach § 40, Abs. 2 des Bundesimmissionsschutzgesetzes / H.-U. Pfeffer, J. Friesel, G. Elbers, R. Beier, K. Ellermann
JF  - Drei Jahrzehnte Luftqualitätsüberwachung : Vorträge und Berichte zum Kolloquium "Drei Jahrzehnte Luftqualitätsüberwachung - Bilanz und Perspektiven" am 11. November 1993 in Essen / [Hrsg.: Landesanstalt für Immissionsschutz Nordrhein-Westfalen. Red. Bearb.: Robert Niesenhaus]
Y1  - 1993
N1  - LIS-Berichte ; 110 ;
SP  - 117
CY  - Essen
ER  - 
TY  - JOUR
A1  - Baumann, Marcus
A1  - Hirche, H.-J.
A1  - Kattner, G.
A1  - Gradinger, R.
T1  - Plankton distribution and the impact of copepod grazing on primary production in Fram Strait, Greenland Sea / Hirche, H.-J. ; Baumann, M.E.M. ; Kattner, G.; Gradinger, R.
JF  - Journal of Marine Systems. 2 (1991), H. 3-4
Y1  - 1991
SN  - 0924-7963
SP  - 477
EP  - 494
ER  - 
TY  - JOUR
A1  - Michalak, Ewa Malgorzata
A1  - Nacerddine, Karim
A1  - Pietersen, Alexandra
A1  - Beuger, Vincent
A1  - Pawlitzky, Inka
A1  - Cornelissen-Steijger, Paulien
A1  - Wientjens, Ellen
A1  - Tanger, Ellen
A1  - Seibler, Jost
A1  - Lohuizen, Maarten van
A1  - Jonkers, Jos
T1  - Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool
JF  - Stem Cells
Y1  - 2013
U6  - http://dx.doi.org/10.1002/stem.1437
SN  - 1549-4918
VL  - Vol 31
IS  - 9
SP  - 1910
EP  - 1920
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Mang, Thomas
A1  - Kricheldorf, Hans R.
A1  - Jonté, J. Michael
T1  - Polylactones, 2. Copolymerization of glycolide with β-propiolactone,  χ-butyrolactone or δ-valerolactone / Kricheldorf, Hans R. ; Mang, Thomas ; Jonté, J. Michael
JF  - Die makromolekulare Chemie. 186 (1985), H. 5
Y1  - 1985
SN  - 1022-1352
SP  - 955
EP  - 976
ER  - 
TY  - JOUR
A1  - Mang, Thomas
A1  - Kricheldorf, Hans R.
A1  - Jonté, J. Michael
T1  - Polylactones. 1. Copolymerizations of glycolide and &beta-caprolactone / Kricheldorf, Hans R. ; Mang, Thomas ; Jonté, J. Michael
JF  - Macromolecules. 17 (1984), H. 10
Y1  - 1984
SN  - 0024-9297
SP  - 2173
EP  - 2181
ER  - 
TY  - JOUR
A1  - Mang, Thomas
T1  - Polymer Magnetic Particles for Isolating Biomolecules, Especially Nucleic Acids
JF  - Biomedizinische Technik = Biomedical Engineering. 49 (2004), H. 2
Y1  - 2004
SN  - 0013-5585
SP  - 1008
EP  - 1009
ER  - 
TY  - JOUR
A1  - Scherer, Ulrich W.
A1  - Hör, G.
A1  - Hertel, A.
T1  - Positronen-Emissions-Tomographie des Herzens / G. Hör, A. Hertel, U. W. Scherer
JF  - Herzerkrankungen und Interventionsmöglichkeiten / F. Unger [Hrsg.]
Y1  - 1998
SN  - 3-540-62916-5
SP  - 236
EP  - 263
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Oosterhuis, Koen
A1  - Öhlschläger, Peter
A1  - Berg, Joost H. van den
A1  - Toebes, Mireille
A1  - Gomez, Raquel
A1  - Schumacher, Ton N.
A1  - Haanen, John B.
T1  - Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7
JF  - International Journal of Cancer
Y1  - 2011
SN  - 1097-0215
VL  - 129
IS  - 2
SP  - 397
EP  - 406
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Henken, F. E.
A1  - Oosterhuis, K.
A1  - Öhlschläger, Peter
A1  - Bosch, L.
A1  - Hooijberg, E.
A1  - Haanen, J. B. A. G.
A1  - Steenbergen, R. D. M.
T1  - Preclinical safety evaluation of DNA vaccines encoding modified HPV16 E6 and E7
JF  - Vaccine
N2  - Persistent infection with high-risk human papillomaviruses (hrHPV) can result in the formation of anogenital cancers. As hrHPV proteins E6 and E7 are required for cancer initiation and maintenance, they are ideal targets for immunotherapeutic interventions. Previously, we have described the development of DNA vaccines for the induction of HPV16 E6 and E7 specific T cell immunity. These vaccines consist of ‘gene-shuffled’ (SH) versions of HPV16 E6 and E7 that were fused to Tetanus Toxin Fragment C domain 1 (TTFC) and were named TTFC-E6SH and TTFC-E7SH. Gene-shuffling was performed to avoid the risk of inducing malignant transformation at the vaccination site. Here, we describe the preclinical safety evaluation of these candidate vaccines by analysis of their transforming capacity in vitro using established murine fibroblasts (NIH 3T3 cells) and primary human foreskin keratinocytes (HFKs). We demonstrate that neither ectopic expression of TTFC-E6SH and TTFC-E7SH alone or in combination enabled NIH 3T3 cells to form colonies in soft agar. In contrast, expression of HPV16 E6WT and E7WT alone or in combination resulted in effective transformation. Similarly, retroviral transduction of HFKs from three independent donors with both TTFC-E6SH and TTFC-E7SH alone or in combination did not show any signs of immortalization. In contrast, the combined expression of E6WT and E7WT induced immortalization in HFKs from all donors. Based on these results we consider it justified to proceed to clinical evaluation of DNA vaccines encoding TTFC-E6SH and TTFC-E7SH in patients with HPV16 associated (pre)malignancies.
Y1  - 2012
U6  - http://dx.doi.org/10.1016/j.vaccine.2012.04.013
SN  - 0264-410X
VL  - 30
IS  - 28
SP  - 4259
EP  - 4266
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - BOOK
A1  - Lauth, Jakob
A1  - Harreus, Albrecht
A1  - Götz, Norbert
A1  - Rang, Harald [u.a.]
T1  - Preparation O-(2-Hydroxyalkyl)Oximes = of Verfahren zur Herstellung von O-(2-Hydroxy)Oximen : Europäische Patentschrift EP0775107B1 ; Veröffentlichungstag im Patentblatt: 18.11.1999 / Anmelder: BASF AG, 67063 Ludwigshafen. Erfinder: Albrecht Harreus ; Norbert Götz ; Harald Rang ... Günter Lauth
Y1  - 1999
N1  - Volltext über Datenbank: http://publikationen.dpma.de/ ; Text in engl. ; Deutsche Übersetzung unter DE69512786T2 ; Internationale Veröffentlichungsnummer: WO 96/04238
PB  - Europäisches Patentamt
CY  - [München u.a.]
ER  - 
TY  - PAT
A1  - Lauth, Jakob
A1  - Wolf, Gerhard
A1  - Burkhart, Bernd
T1  - Preparation of alkoxylation products in the presence of mixed hydroxides modified with additives : United States Patent ; patent number 5,741,947 ; date of patent: Apr. 21, 1998 / assignee: BASF Aktiengesellschaft. Inventors: Gerhard Wolf ; Bernd Burkhart ; Guenter Lauth ...
Y1  - 1998
N1  - Barcode: US005741947A ; Volltext über Datenbank: http://www.google.com/patents
PB  - [United States Trademark and Patent Office]
CY  - [Alexandria, VA]
ER  - 
TY  - PAT
A1  - Lauth, Jakob
A1  - Müller, Ulrich
A1  - Hoelderich, Wolfgang
T1  - Preparation of aluminophosphates and silicoaluminophosphates having the AEL structure using 1,2-bis-( 4-pyridyl)-ethane : United States Patent ; patent number 5,324,493 ; date of patent: Jun. 28, 1994 / assignee: BASF Aktiengesellschaft. Inventors: Ulrich Mueller ; Wolfgang Hoelderich ; Guenter Lauth
Y1  - 1994
N1  - Barcode: US005324493A ; Volltext über Datenbank: http://www.google.com/patents
PB  - [United States Trademark and Patent Office]
CY  - [Alexandria, VA]
ER  - 
TY  - PAT
A1  - Lauth, Jakob
A1  - Dingerdissen, Uwe
A1  - Henne, Andreas
T1  - Preparation of amines  : United States Patent ; patent number 5,817,871 ; date of patent: Oct. 6, 1998 / Assignee: BASF Aktiengesellschaft. Inventors: Uwe Dingerdissen ; Gunter Lauth ; Andreas Henne ....
Y1  - 1998
N1  - Barcode: US005817871A ; Volltext über Datenbank: http://www.google.com/patents ; Falsche Namensansetzung: Gunter ...
PB  - [United States Trademark and Patent Office]
CY  - [Alexandria, VA]
ER  -