TY  - THES
A1  - Albracht, Kirsten
T1  - Influence of mechanical properties of the leg extensor muscletendon units on running economy
Y1  - 2010
N1  - Cologne, German Sport Univ., Diss., 2010
PB  - Deutsche Sporthochschule Köln
CY  - Köln
ER  - 
TY  - JOUR
A1  - Degering, Christian
A1  - Eggert, Thorsten
A1  - Puls, Michael
A1  - Bongaerts, Johannes
A1  - Evers, Stefan
A1  - Maurer, Karl-Heinz
A1  - Jaeger, Karl-Erich
T1  - Optimization of protease secretion in Bacillus subtilis and Bacillus licheniformis by screening of homologous and herologous signal peptides
JF  - Applied and environmental microbiology
N2  - Bacillus subtilis and Bacillus licheniformis are widely used for the large-scale industrial production of proteins. These strains can efficiently secrete proteins into the culture medium using the general secretion (Sec) pathway. A characteristic feature of all secreted proteins is their N-terminal signal peptides, which are recognized by the secretion machinery. Here, we have studied the production of an industrially important secreted protease, namely, subtilisin BPN′ from Bacillus amyloliquefaciens. One hundred seventy-three signal peptides originating from B. subtilis and 220 signal peptides from the B. licheniformis type strain were fused to this secretion target and expressed in B. subtilis, and the resulting library was analyzed by high-throughput screening for extracellular proteolytic activity. We have identified a number of signal peptides originating from both organisms which produced significantly increased yield of the secreted protease. Interestingly, we observed that levels of extracellular protease were improved not only in B. subtilis, which was used as the screening host, but also in two different B. licheniformis strains. To date, it is impossible to predict which signal peptide will result in better secretion and thus an improved yield of a given extracellular target protein. Our data show that screening a library consisting of homologous and heterologous signal peptides fused to a target protein can identify more-effective signal peptides, resulting in improved protein export not only in the original screening host but also in different production strains.
Y1  - 2010
U6  - https://doi.org/10.1128/AEM.01146-10
SN  - 1098-5336 (E-Journal); 0003-6919 (Print); 0099-2240 (Print)
VL  - 76
IS  - 19
SP  - 6370
EP  - 6378
PB  - American Society for Microbiology
CY  - Washington, DC
ER  - 
TY  - CHAP
A1  - Reimer, Lars
A1  - Braun, Carsten
A1  - Wellmer, Georg
A1  - Behr, Marek
A1  - Ballmann, Josef
T1  - Development of a modular method for computational aero-structural analysis of aircraft
T2  - Summary of flow modulation and fluid-structure interaction findings. Results of the Collaborative Research Center SFB 401 at the RWTH Aachen University, Aachen, Germany, 1997-2008 / ed.: Wolfgang Schröder. Notes on numerical fluid mechanics and multidisciplinary design. Vol. 109
Y1  - 2010
SN  - 978-3-642-04087-0
SP  - 205
EP  - 238
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Heinz, G.
A1  - Oertel, Mario
A1  - Bung, Daniel Bernhard
ED  - Janssen, Robert
T1  - Investigations on a cooling water system for a gas tubine facility concerning air vortexes and sediment transport
T2  - Hydraulic structures: useful water harvesting systems or relics? : Third International Junior Researcher and Engineer Workshop on Hydraulic Structures (IJREWHS'10) : Edinburgh, Scotland, U.K., 2-3 May 2010
Y1  - 2010
SN  - 9781742720159
SP  - 109
EP  - 116
PB  - School of Civil Engineering, The University of Queensland
CY  - Brisbane
ER  - 
TY  - CHAP
A1  - Dachwald, Bernd
T1  - Solar sail dynamics and control
T2  - Encyclopedia of Aerospace Engineering
N2  - Solar sails are large and lightweight reflective structures that are propelled by solar radiation pressure. This chapter covers their orbital and attitude dynamics and control. First, the advantages and limitations of solar sails are discussed and their history and development status is outlined. Because the dynamics of solar sails is governed by the (thermo-)optical properties of the sail film, the basic solar radiation pressure force models have to be described and compared before parameters to measure solar sail performance can be defined. The next part covers the orbital dynamics of solar sails for heliocentric motion, planetocentric motion, and motion at Lagrangian equilibrium points. Afterwards, some advanced solar radiation pressure force models are described, which allow to quantify the thrust force on solar sails of arbitrary shape, the effects of temperature, of light incidence angle, of surface roughness, and the effects of optical degradation of the sail film in the space environment. The orbital motion of a solar sail is strongly coupled to its rotational motion, so that the attitude control of these soft and flexible structures is very challenging, especially for planetocentric orbits that require fast attitude maneuvers. Finally, some potential attitude control methods are sketched and selection criteria are given.
KW  - solar sail
KW  - sailcraft
KW  - orbital dynamics
KW  - orbit control
KW  - attitude dynamics
Y1  - 2010
U6  - https://doi.org/10.1002/9780470686652.eae292
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Zhubanova, Azhar A.
A1  - Aknazarov, S. K.
A1  - Mansurov, Zulkhair
A1  - Digel, Ilya
A1  - Kozhalakova, A. A.
A1  - Akimbekov, Nuraly S.
A1  - O'Heras, Carlos
A1  - Tazhibayeva, S.
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Adsorption of bacterial Lipopolysaccharides and blood plasma proteins on modified carbonized materials
N2  - Bacterial lipopolysaccharides (endotoxins) show strong biological effects at very low concentrations in human beings and many animals when entering the blood stream. These include affecting structure and function of organs and cells, changing metabolic functions, raising body temperature, triggering the coagulation cascade, modifying hemodynamics and causing septic shock. Because of this toxicity, the removal of even minute amounts is essential for safe parenteral administration of drugs and also for septic shock patients' care. The absence of a general method for endotoxin removal from liquid interfaces urgently requires finding new methods and materials to overcome this gap. Nanostructured carbonized plant parts is a promising material that showed good adsorption properties due to its vast pore network and high surface area. The aim of this study was comparative measurement of endotoxin- and blood proteins-related adsorption rate and adsorption capacity for different carboneous materials produced at different temperatures and under different surface modifications. As a main surface modificator, positively cbarged polymer, polyethileneimine (PEl) was used. Activated carbon materials showed good adsorption properties for LPS and some proteins used in the experiments. During the batch experiments, several techniques (dust removal, autoclaving) were used and optimized for improving the material's adsorption behavior. Also, with the results obtained it was possible to differentiate the materials according to their adsorption capacity and kinetic characteristics. Modification of the surface apparently has not affected hemoglobin binding to the adsorbent's surface. Obtained adsorption isotherms can be used as a powerful tool for designing of future column-based setups for blood purification from LPS, which is especially important for septic shock treatment.
KW  - Kohlenstofffaser
KW  - Lipopolysaccharide
KW  - nanostrukturierte carbonisierte Pflanzenteile
KW  - lipopolysaccharides
KW  - nanostructured carbonized plant parts
Y1  - 2010
ER  - 
TY  - CHAP
A1  - Kapoor, Hrshi
A1  - Braun, Carsten
A1  - Boller, Christian
ED  - Casciati, Fabio
T1  - Modelling and optimisation of maintenance intervals to realize structural health monitoring applications on aircraft
T2  - Structural health monitoring 2010 : proceedings of the Fifth European Workshop on Structural Health Monitoring held at Sorrento, Naples, Italy, June 28 - July 4, 2010 ; [EWSHM]
Y1  - 2010
SN  - 978-1-60595-024-2
SP  - 55
EP  - 63
PB  - DEStech Publ.
CY  - Lancaster, Pa.
ER  - 
TY  - JOUR
A1  - Ferrein, Alexander
T1  - golog.lua: Towards a Non-Prolog Implementation of Golog for Embedded Systems
Y1  - 2010
SP  - 20
EP  - 28
ER  - 
TY  - JOUR
A1  - Ferrein, Alexander
T1  - golog.lua: Towards a Non-Prolog Implementation of Golog for Embedded Systems
JF  - Cognitive Robotics / Lakemeyer, Gerhard (ed.)
Y1  - 2010
N1  - Dagstuhl Seminar Proceedings ; 10081
SP  - 1
EP  - 15
ER  - 
TY  - CHAP
A1  - Reindl, Lukas
A1  - Park, Jin
A1  - Norda, Hannah
A1  - Butenweg, Christoph
T1  - Seismic design of masonry walls subject to out-of-plane bending
T2  - Proceedings of the Tenth International Conference on Computational Structures Technology : Valencia, Spain, 14 - 17 September 2010 / organised in association with: Universidad Politecnica de Valencia ... Ed. by B. H. V. Topping ...
Y1  - 2010
SN  - 978-1-905088-36-2
U6  - https://doi.org/10.4203/ccp.93.348
SP  - Paper 348
PB  - Civil-Comp Press
CY  - Kippen
ER  - 
TY  - JOUR
A1  - Akimbekov, Nuraly S.
A1  - Zhubanova, A. A.
A1  - Mansurov, Z. A.
A1  - Digel, Ilya
A1  - Artmann, Gerhard
A1  - Temiz Artmann, Aysegül
T1  - Use of Carbonized Rise Shell for the local treatment of wounds
JF  - Eurasian ChemTech Journal
N2  - On the model of musculocutaneous wound in rats, the effect of applicative sorption by carbonized rise shell (CRS) on the healing of festering wound was studied. It has been shown, that cytological changes end with rapid scar formation. The use of CRS at the period of severe purulent wound contributes to its favorable course, prevents the development of complications of the animals from sepsis.
Y1  - 2010
U6  - https://doi.org/10.18321/ectj35
SN  - 2522-4867
VL  - 12
IS  - 2
SP  - 133
EP  - 138
PB  - Institute of Combustion Problems
CY  - Almaty
ER  - 
TY  - CHAP
A1  - Bung, Daniel Bernhard
T1  - A comparative study of self-aerated stepped spillway and smooth invert chute flow: the effect of step-induced macro roughness
T2  - 5th Chinese-German Joint Symposium on Hydraulic and Ocean Engineering : CG JOINT 2010
Y1  - 2010
SN  - 978-7-5618-3671-2
SP  - 451
EP  - 456
PB  - Univ. Press
CY  - Tianjin
ER  - 
TY  - JOUR
A1  - Leimena, W.
A1  - Artmann, Gerhard
A1  - Dachwald, Bernd
A1  - Temiz Artmann, Aysegül
A1  - Gossmann, Matthias
A1  - Digel, Ilya
T1  - Feasibility of an in-situ microbial decontamination of an ice-melting probe
JF  - Eurasian Chemico-Technological Journal. 12 (2010), H. 2
Y1  - 2010
SN  - 1562-3920
SP  - 145
EP  - 150
ER  - 
TY  - CHAP
A1  - Anthrakidis, Anette
A1  - Rusack, Markus
A1  - Schwarzer, Klemens
T1  - Low effort measurement method of PTC-efficiency
T2  - SolarPACES 2010 : the CSP conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France
Y1  - 2010
SP  - 48
EP  - 49
PB  - Soc. OSC
CY  - Saint Maur
ER  - 
TY  - CHAP
A1  - Kurulgan Demirci, Eylem
A1  - Linder, Peter
A1  - Demirci, Taylan
A1  - Gierkowski, Jessica R.
A1  - Digel, Ilya
A1  - Gossmann, Matthias
A1  - Temiz Artmann, Aysegül
T1  - rhAPC reduces the endothelial cell permeability via a decrease of cellular mechanical contractile tensions : [abstract]
N2  - In this study, the CellDrum technology quanitfying cellular mechanical tension on a pico-scale was used to investigate the effect of LPS (lipopolysaccharide) on HAoEC (Human Aortic Endothelial Cell) tension.
KW  - Endothelzelle
KW  - Sepsis
KW  - kontraktile Spannung
KW  - rhAPC
KW  - contractile tension
KW  - rhAPC
KW  - celldrum technology
Y1  - 2010
ER  - 
TY  - JOUR
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Abouzar, Maryam H.
A1  - Wenmackers, Sylvia
A1  - Janssens, Stoffel D.
A1  - Haenen, Ken
A1  - Wagner, Patrick
A1  - Schöning, Michael Josef
T1  - Capacitive field-effect (bio-)chemical sensors based on nanocrystalline diamond films
JF  - Diamond Electronics and Bioelectronics — Fundamentals to Applications III, edited by P. Bergonzo, [u.a.]
Y1  - 2010
N1  - MRS Proceedings Volume 1203 paper 1203-J17-31 ; Mater. Res. Soc. Sympos. Proc. Vol 1203 (2010) ; Materials Research Society
SP  - 1
EP  - 6
ER  - 
TY  - CHAP
A1  - Lehnertz, Klaus
A1  - Bialonski, Stephan
A1  - Horstmann, Marie-Therese
A1  - Krug, Dieter
A1  - Rothkegel, Alexander
A1  - Staniek, Matthäus
A1  - Wagner, Tobias
T1  - Epilepsy
T2  - Reviews of Nonlinear Dynamics and Complexity, Volume 2
Y1  - 2010
SN  - 9783527628001
U6  - https://doi.org/10.1002/9783527628001.ch5
SP  - 159
EP  - 200
PB  - Wiley-VCH
ER  - 
TY  - JOUR
A1  - Niemüller, Tim
A1  - Ferrein, Alexander
A1  - Lakemeyer, Gerhard
T1  - A Lua-based Behavior Engine for Controlling the Humanoid Robot Nao
JF  - RoboCup 2009: Robot Soccer World Cup XIII
Y1  - 2010
N1  - Lecture Notes in Computer Science ; 5949
SP  - 240
EP  - 251
ER  - 
TY  - JOUR
A1  - Grottke, O.
A1  - Braunschweig, T.
A1  - Philippen, B.
A1  - Gatzweiler, Karl-Heinz
A1  - Gronloh, N.
A1  - Staat, Manfred
A1  - Rossaint, R.
A1  - Tolba, R.
T1  - A New Model for Blunt Liver Injuries in the Swine
JF  - European Surgical Research. 44 (2010), H. 2
Y1  - 2010
SN  - 1421-9921
SP  - 65
EP  - 73
ER  - 
TY  - JOUR
A1  - Abouzar, Maryam H.
A1  - Pedraza, A. M.
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
T1  - Label-free DNA hybridization and denaturation detection by means of field-effect nanoplate SOI capacitors functionalized with gold nanoparticles
JF  - Procedia Engineering. 5 (2010)
Y1  - 2010
SN  - 1877-7058
N1  - Proc. Eurosensors XXIV, September 5–8, 2010, Linz, Austria
SP  - 918
EP  - 921
ER  -