TY  - JOUR
A1  - Bhattarai, Aroj
A1  - Horbach, Andreas
A1  - Staat, Manfred
A1  - Kowalczyk, Wojciech
A1  - Tran, Thanh Ngoc
T1  - Virgin passive colon biomechanics and a literature review of active contraction constitutive models
JF  - Biomechanics
N2  - The objective of this paper is to present our findings on the biomechanical aspects of the virgin passive anisotropic hyperelasticity of the porcine colon based on equibiaxial tensile experiments. Firstly, the characterization of the intestine tissues is discussed for a nearly incompressible hyperelastic fiber-reinforced Holzapfel–Gasser–Ogden constitutive model in virgin passive loading conditions. The stability of the evaluated material parameters is checked for the polyconvexity of the adopted strain energy function using positive eigenvalue constraints of the Hessian matrix with MATLAB. The constitutive material description of the intestine with two collagen fibers in the submucosal and muscular layer each has been implemented in the FORTRAN platform of the commercial finite element software LS-DYNA, and two equibiaxial tensile simulations are presented to validate the results with the optical strain images obtained from the experiments. Furthermore, this paper also reviews the existing models of the active smooth muscle cells, but these models have not been computationally studied here. The review part shows that the constitutive models originally developed for the active contraction of skeletal muscle based on Hill’s three-element model, Murphy’s four-state cross-bridge chemical kinetic model and Huxley’s sliding-filament hypothesis, which are mainly used for arteries, are appropriate for numerical contraction numerical analysis of the large intestine.
KW  - virgin passive
KW  - strain energy function
KW  - smooth muscle contraction
KW  - viscoelasticity
KW  - damage
Y1  - 2022
U6  - https://doi.org/10.3390/biomechanics2020013
SN  - 2673-7078
VL  - 2
IS  - 2
SP  - 138
EP  - 157
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Ullrich, Sebastian
A1  - Grottke, Oliver
A1  - Rossaint, Rolf
A1  - Staat, Manfred
A1  - Deserno, Thomas M.
A1  - Kuhlen, Torsten
T1  - Virtual Needle Simulation with Haptics for Regional Anaesthesia
Y1  - 2010
N1  - IEEE Virtual Reality 2010, Workshop on Medical Virtual Environments, Waltham, MA, USA, March 21, 2010
SP  - 1
EP  - 3
ER  - 
TY  - JOUR
A1  - Bartella, Alexander K.
A1  - Kamal, Mohammad
A1  - Scholl, Ingrid
A1  - Schiffer, Stefan
A1  - Steegmann, Julius
A1  - Ketelsen, Dominik
A1  - Hölzle, Frank W.
A1  - Lethaus, Bernd
T1  - Virtual reality in preoperative imaging in maxillofacial surgery: implementation of “the next level”?
JF  - British Journal of Oral and Maxillofacial Surgery
Y1  - 2019
U6  - https://doi.org/10.1016/j.bjoms.2019.02.014
SN  - 0266-4356
VL  - 57
IS  - 7
SP  - 644
EP  - 648
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Reisgen, Uwe
A1  - Schleser, Markus
A1  - Mokrov, Oleg
A1  - Zabirov, Alexander
T1  - Virtual welding equipment for simulation of GMAW processes with integration of power source regulation
JF  - Frontiers of materials science
Y1  - 2011
SN  - 2095-0268 (E-Journal); 2095-025X (Print)
VL  - Vol. 5
IS  - Iss. 2
SP  - 79
EP  - 89
PB  - Springer
CY  - Berlin
ER  - 
TY  - BOOK
A1  - Boonzaaijer, Karel
A1  - Helmig, Ilka
A1  - Bergerhausen, Johannes
A1  - Beudaert, Matthieu
T1  - Vision - space for imagination
T2  - Vision - ruimte voor verbeelding
Y1  - 2010
SN  - 978-90-5856-357-6
N1  - Texte Engl. und Niederländ.
PB  - Stichting Kunstboek
CY  - Oostkamp
ER  - 
TY  - CHAP
A1  - Vladova, Gergana
A1  - Ullrich, André
A1  - Sultanow, Eldar
A1  - Tobolla, Marinho
A1  - Sebrak, Sebastian
A1  - Czarnecki, Christian
A1  - Brockmann, Carsten
T1  - Visual analytics for knowledge management
T2  - INFORMATIK 2023 - Designing Futures: Zukünfte gestalten
N2  - The management of knowledge in organizations considers both established long-term processes and cooperation in agile project teams. Since knowledge can be both tacit and explicit, its transfer from the individual to the organizational knowledge base poses a challenge in organizations. This challenge increases when the fluctuation of knowledge carriers is exceptionally high. Especially in large projects in which external consultants are involved, there is a risk that critical, company-relevant knowledge generated in the project will leave the company with the external knowledge carrier and thus be lost. In this paper, we show the advantages of an early warning system for knowledge management to avoid this loss. In particular, the potential of visual analytics in the context of knowledge management systems is presented and discussed. We present a project for the development of a business-critical software system and discuss the first implementations and results.
Y1  - 2023
SN  - 978-3-88579-731-9
U6  - https://doi.org/10.18420/inf2023_187
SN  - 1617-5468
N1  - INFORMATIK 2023, 26. - 29. September 2023, Berlin
SP  - 1851
EP  - 1870
PB  - GI - Gesellschaft für Informatik
CY  - Bonn
ER  - 
TY  - JOUR
A1  - Elsen, Ingo
A1  - Kraiss, Karl-Friedrich
A1  - Krumbiegel, Dirk
A1  - Walter, Peter
A1  - Wickel, Jochen
T1  - Visual information retrieval for 3D product identification: a midterm report
JF  - KI - Künstliche Intelligenz
Y1  - 1999
SN  - 1610-1987
SN  - 0933-1875
VL  - 13
IS  - 1
SP  - 64
EP  - 67
PB  - Springer
CY  - Berlin
ER  - 
TY  - BOOK
A1  - Digel, Ilya
A1  - Zhubanova, Azhar Ahmetovna
A1  - Akimbekov, Nuraly S.
T1  - Visual Virology
Y1  - 2012
SN  - 978-601-247-298-1
N1  - Text kasachisch, russisch, englisch
CY  - Almaty
ER  - 
TY  - JOUR
A1  - Miyamoto, Ko-ichiro
A1  - Bing, Yu
A1  - Wagner, Torsten
A1  - Yoshinobu, Tatsuo
A1  - Schöning, Michael Josef
T1  - Visualization of Defects on a Cultured Cell Layer by Utilizing Chemical Imaging Sensor
JF  - Procedia Engineering
N2  - The chemical imaging sensor is a field-effect sensor which is able to visualize both the distribution of ions (in LAPS mode) and the distribution of impedance (in SPIM mode) inthe sample. In this study, a novel wound-healing assay is proposed, in which the chemical imaging sensor operated in SPIM mode is applied to monitor the defect of a cell layer brought into proximity of the sensing surface.A reduced impedance inside the defect, which was artificially formed ina cell layer, was successfully visualized in a photocurrent image.
Y1  - 2015
U6  - https://doi.org/10.1016/j.proeng.2015.08.806
SN  - 1877-7058
N1  - Part of special issue "Eurosensors 2015"
VL  - 120
SP  - 936
EP  - 939
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Miyamoto, Ko-ichiro
A1  - Hirayama, Yuji
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Yoshinobu, Tatsuo
T1  - Visualization of enzymatic reaction in a microfluidic channel using chemical imaging sensor
JF  - Electrochimica acta
Y1  - 2013
SN  - 1873-3859 (E-Journal); 0013-4686 (Print)
SP  - Publ. online
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Kramer, Pia
A1  - Bragard, Michael
A1  - Ritz, Thomas
A1  - Ferfer, Ute
A1  - Schiffers, Tim
T1  - Visualizing, Enhancing and Predicting Students’ Success through ECTS Monitoring
T2  - 2024 IEEE Global Engineering Education Conference (EDUCON)
N2  - This paper serves as an introduction to the ECTS monitoring system and its potential applications in higher education. It also emphasizes the potential for ECTS monitoring to become a proactive system, supporting students by predicting academic success and identifying groups of potential dropouts for tailored support services. The use of the nearest neighbor analysis is suggested for improving data analysis and prediction accuracy.
KW  - Monitoring
KW  - Engineering education
KW  - Data visualization
KW  - Accuracy
KW  - Data analysis
Y1  - 2024
U6  - https://doi.org/10.1109/EDUCON60312.2024.10578652
SN  - 2165-9559
SN  - 2165-9567 (eISSN)
N1  - 2024 IEEE Global Engineering Education Conference (EDUCON), 08-11 May 2024, Kos Island, Greece
PB  - IEEE
CY  - New York, NY
ER  - 
TY  - CHAP
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Sherelkhan, Dinara K.
A1  - Razzaque, Mohammed S.
T1  - Vitamin D and Phosphate Interactions in Health and Disease
T2  - Phosphate Metabolism
N2  - Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.
KW  - Vitamin D
KW  - PTH
KW  - Phosphate
KW  - FGF23
KW  - Klotho
Y1  - 2022
SN  - 978-3-030-91621-3
U6  - https://doi.org/10.1007/978-3-030-91623-7_5
SP  - 37
EP  - 46
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Sherelkhan, Dinara K.
A1  - Lutfor, Afzalunnessa B.
A1  - Razzaque, Mohammed S.
T1  - Vitamin D and the Host-Gut Microbiome: A Brief Overview
JF  - Acta Histochemica et Cytochemica
N2  - There is a growing body of evidence for the effects of vitamin D on intestinal host-microbiome interactions related to gut dysbiosis and bowel inflammation. This brief review highlights the potential links between vitamin D and gut health, emphasizing the role of vitamin D in microbiological and immunological mechanisms of inflammatory bowel diseases. A comprehensive literature search was carried out in PubMed and Google Scholar using combinations of keywords “vitamin D,” “intestines,” “gut microflora,” “bowel inflammation”. Only articles published in English and related to the study topic are included in the review. We discuss how vitamin D (a) modulates intestinal microbiome function, (b) controls antimicrobial peptide expression, and (c) has a protective effect on epithelial barriers in the gut mucosa. Vitamin D and its nuclear receptor (VDR) regulate intestinal barrier integrity, and control innate and adaptive immunity in the gut. Metabolites from the gut microbiota may also regulate expression of VDR, while vitamin D may influence the gut microbiota and exert anti-inflammatory and immune-modulating effects. The underlying mechanism of vitamin D in the pathogenesis of bowel diseases is not fully understood, but maintaining an optimal vitamin D status appears to be beneficial for gut health. Future studies will shed light on the molecular mechanisms through which vitamin D and VDR interactions affect intestinal mucosal immunity, pathogen invasion, symbiont colonization, and antimicrobial peptide expression.
Y1  - 2020
U6  - https://doi.org/10.1267/ahc.20011
SN  - 1347-5800
VL  - 53
IS  - 3
SP  - 33
EP  - 42
PB  - Japan Society of Histochemistry and Cytochemistry
CY  - Osaka
ER  - 
TY  - JOUR
A1  - Emons, H.
A1  - Baade, A.
A1  - Schöning, Michael Josef
T1  - Voltammetric determination of heavy metals in microvolumes of rain water
JF  - Electroanalysis. 12 (2000), H. 15
Y1  - 2000
SN  - 1040-0397
SP  - 1171
EP  - 1176
ER  - 
TY  - JOUR
A1  - Emons, H.
A1  - Glück, O.
A1  - Hüllenkremer, B.
A1  - Schöning, Michael Josef
T1  - Voltohmmetry as an alternative detection method at polycrystalline metal film electrodes
JF  - Electroanalysis. 13 (2001), H. 8-9
Y1  - 2001
SN  - 1040-0397
SP  - 677
EP  - 680
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Hüllenkremer, B.
A1  - Glück, O.
A1  - Lüth, H.
A1  - Emons, H.
T1  - Voltohmmetry – a novel sensing principle for heavy metal determination in aqueous solutions
JF  - Sensors and Actuators B. 78 (2001), H. 1-3
Y1  - 2001
SN  - 0925-4005
SP  - 275
EP  - 280
ER  - 
TY  - JOUR
A1  - Emons, H.
A1  - Glück, O.
A1  - Schöning, Michael Josef
T1  - Voltohmmetry – An alternative detection principle at ultrathin metal electrodes in solution
JF  - Chemical and biological sensors and analytical methods : proceedings of the international symposium / Sensor, Physical Electrochemistry, and Organic and Biological Electrochemistry Divisions. Ed.: M. Butler
Y1  - 2001
SN  - 1-56677-351-2
N1  - International Symposium: Chemical and Biological Sensors and Analytical Methods ; (2 : 2001.)
SP  - 1
EP  - 3
PB  - Electrochemical Society
CY  - Pennington, NJ
ER  - 
TY  - CHAP
A1  - Karimi, Iman
A1  - Butenweg, Christoph
A1  - Toll, Britta
T1  - Vulnerability assessment of industrial facilities
T2  - Proceedings of the Tenth International Conference on Civil, Structural and Environmental Engineering Computing : [Rome, Italy, 30. August - 2. September 2005] / ed. by B. H. V. Topping
Y1  - 2005
SN  - 1-905088-00-0
U6  - https://doi.org/10.4203/ccp.81.34
SP  - 34, 73
EP  - 75
PB  - Civil-Comp Press
CY  - Stirling
ER  - 
TY  - JOUR
A1  - Schirra, Julian
A1  - Bissonnette, William
A1  - Bramesfeld, Götz
T1  - Wake-model effects on induced drag prediction of staggered boxwings
JF  - Aerospace
Y1  - 2018
U6  - https://doi.org/10.3390/aerospace5010014
SN  - 2226-4310
VL  - 5
IS  - 1
ER  - 
TY  - JOUR
A1  - Meliß, Michael
A1  - Neskakis, A.
A1  - Plettner-Marliani, J.
A1  - Lange, C.
A1  - Hövelmann, A.
A1  - Schumacher, J.
T1  - Waste water recycling supplied by renewable energies : basic conditions and possible treatment technologies
JF  - Renewable energy. Vol. 14 (1998), iss. 1-4. 6th Arab International Solar Energy Conference: Bringing Solar Energy into the Daylight, Muscat, Sultanate of Oman, 29.03.-01.04.1998
Y1  - 1998
SN  - 1879-0682 (E-Book); 0960-1481 (Print)
SP  - 325
EP  - 331
ER  -