TY - JOUR A1 - Tran, Ngoc Trinh A1 - Trinh, Tu Luc A1 - Dao, Ngoc Tien A1 - Giap, Van Tan A1 - Truong, Manh Khuyen A1 - Dinh, Thuy Ha A1 - Staat, Manfred T1 - FEM shakedown analysis of structures under random strength with chance constrained programming JF - Vietnam Journal of Mechanics N2 - Direct methods, comprising limit and shakedown analysis, are a branch of computational mechanics. They play a significant role in mechanical and civil engineering design. The concept of direct methods aims to determine the ultimate load carrying capacity of structures beyond the elastic range. In practical problems, the direct methods lead to nonlinear convex optimization problems with a large number of variables and constraints. If strength and loading are random quantities, the shakedown analysis can be formulated as stochastic programming problem. In this paper, a method called chance constrained programming is presented, which is an effective method of stochastic programming to solve shakedown analysis problems under random conditions of strength. In this study, the loading is deterministic, and the strength is a normally or lognormally distributed variable. KW - limit analysis KW - shakedown analysis KW - chance constrained programming KW - stochastic programming KW - reliability of structures Y1 - 2022 U6 - https://doi.org/10.15625/0866-7136/17943 SN - 0866-7136 SN - 2815-5882 VL - 44 IS - 4 SP - 459 EP - 473 PB - Vietnam Academy of Science and Technology (VAST) ER - TY - JOUR A1 - Baringhaus, Ludwig A1 - Gaigall, Daniel T1 - A goodness-of-fit test for the compound Poisson exponential model JF - Journal of Multivariate Analysis N2 - On the basis of bivariate data, assumed to be observations of independent copies of a random vector (S,N), we consider testing the hypothesis that the distribution of (S,N) belongs to the parametric class of distributions that arise with the compound Poisson exponential model. Typically, this model is used in stochastic hydrology, with N as the number of raindays, and S as total rainfall amount during a certain time period, or in actuarial science, with N as the number of losses, and S as total loss expenditure during a certain time period. The compound Poisson exponential model is characterized in the way that a specific transform associated with the distribution of (S,N) satisfies a certain differential equation. Mimicking the function part of this equation by substituting the empirical counterparts of the transform we obtain an expression the weighted integral of the square of which is used as test statistic. We deal with two variants of the latter, one of which being invariant under scale transformations of the S-part by fixed positive constants. Critical values are obtained by using a parametric bootstrap procedure. The asymptotic behavior of the tests is discussed. A simulation study demonstrates the performance of the tests in the finite sample case. The procedure is applied to rainfall data and to an actuarial dataset. A multivariate extension is also discussed. KW - Bootstrapping KW - Collective risk model Y1 - 2022 U6 - https://doi.org/10.1016/j.jmva.2022.105154 SN - 0047-259X SN - 1095-7243 VL - 195 IS - Article 105154 PB - Elsevier CY - Amsterdam ER - TY - CHAP A1 - Evans, Benjamin A1 - Braun, Sebastian A1 - Ulmer, Jessica A1 - Wollert, Jörg T1 - AAS implementations - current problems and solutions T2 - 20th International Conference on Mechatronics - Mechatronika (ME) N2 - The fourth industrial revolution presents a multitude of challenges for industries, one of which being the increased flexibility required of manufacturing lines as a result of increased consumer demand for individualised products. One solution to tackle this challenge is the digital twin, more specifically the standardised model of a digital twin also known as the asset administration shell. The standardisation of an industry wide communications tool is a critical step in enabling inter-company operations. This paper discusses the current state of asset administration shells, the frameworks used to host them and their problems that need to be addressed. To tackle these issues, we propose an event-based server capable of drastically reducing response times between assets and asset administration shells and a multi-agent system used for the orchestration and deployment of the shells in the field. KW - Industry 4.0 KW - Multi-agent Systems KW - Digital Twin KW - Asset Administration Shell Y1 - 2022 SN - 978-1-6654-1040-3 U6 - https://doi.org/10.1109/ME54704.2022.9982933 N1 - 20th International Conference on Mechatronics - Mechatronika (ME), 07-09 December 2022, Pilsen, Czech Republic PB - IEEE CY - New York, NY ER - TY - CHAP A1 - Weber, Felix A1 - Bomholt, Frederik A1 - Butenweg, Christoph ED - Bergmeister, Konrad ED - Fingerloos, Frank ED - Wörner, Johann-Dietrich T1 - Erdbeben- und Schwingungsschutz von Bauwerken T2 - 2023 BetonKalender: Wasserundurchlässiger Beton, Brückenbau N2 - Dieser Beitrag beschreibt die herkömmlichen Maßnahmen wie die Kapazitätsbemessung der Tragwerksstruktur, die Isolation des Bauwerks mittels Basisisolatoren, die Dämpfungserhöhung der Struktur mittels Inter-Story-Dämpfern und die Schwingungsreduktion mittels Schwingungstilgern gegen Einwirkungen durch Erdbeben, Wind, Verkehr und Personen auf die Bauwerke. Ergänzend wird die erdbebengerechte Auslegung und Isolation von nichttragenden Bauteilen behandelt. Für die betrachteten Systeme werden die Bewegungsdifferenzialgleichungen unter Berücksichtigung der wesentlichen Nichtlinearitäten angegeben. Die vorgestellten Weiterentwicklungen in den Bereichen der Basisisolatoren, Dämpfern und Schwingungstilgern zeigen, dass das modellbasierte Design mittels Simulation ein sehr effektives, ökonomisches und dank der heutigen Computerleistung auch zeiteffizientes Werkzeug darstellt. Y1 - 2022 SN - 9783433611180 SN - 9783433033753 U6 - https://doi.org/10.1002/9783433611180.ch16 N1 - Beton-Kalender, 112. Jahrgang (2023): Wasserundurchlässiger Beton, Brückenbau ausleihbar unter der Sig. 11 XCF 3-2023,2 SP - 779 EP - 859 PB - Ernst & Sohn CY - Berlin ER - TY - CHAP A1 - Gkatzogias, Konstantinos A1 - Veljkoviv, Ana A1 - Pohoryles, Daniel A. A1 - Tsionis, Georgios A1 - Bournas, Dionysios A. A1 - Crowley, Helen A1 - Norlén, Hedvig A1 - Butenweg, Christoph A1 - Gervasio, Helena A1 - Manfredi, Vincenzo A1 - Masi, Angelo A1 - Zaharieva, Roumiana ED - Gkatzogias, Konstantinos ED - Tsionis, Georgios T1 - Policy practice and regional impact assessment for building renovation T2 - REEBUILD Integrated Techniques for the Seismic Strengthening & Energy Efficiency of Existing Buildings N2 - The work presented in this report provides scientific support to building renovation policies in the EU by promoting a holistic point of view on the topic. Integrated renovation can be seen as a nexus between European policies on disaster resilience, energy efficiency and circularity in the building sector. An overview of policy measures for the seismic and energy upgrading of buildings across EU Member States identified only a few available measures for combined upgrading. Regulatory framework, financial instruments and digital tools similar to those for energy renovation, together with awareness and training may promote integrated renovation. A framework for regional prioritisation of building renovation was put forward, considering seismic risk, energy efficiency, and socioeconomic vulnerability independently and in an integrated way. Results indicate that prioritisation of building renovation is a multidimensional problem. Depending on priorities, different integrated indicators should be used to inform policies and accomplish the highest relative or most spread impact across different sectors. The framework was further extended to assess the impact of renovation scenarios across the EU with a focus on priority regions. Integrated renovation can provide a risk-proofed, sustainable, and inclusive built environment, presenting an economic benefit in the order of magnitude of the highest benefit among the separate interventions. Furthermore, it presents the unique capability of reducing fatalities and energy consumption at the same time and, depending on the scenario, to a greater extent. Y1 - 2022 SN - 978-92-76-60454-9 U6 - https://doi.org/10.2760/883122 SN - 1831-9424 SP - 1 EP - 68 PB - Publications Office of the European Union CY - Luxembourg ER - TY - CHAP A1 - Butenweg, Christoph ED - Vacareanu, Radu ED - Ionescu, Constantin T1 - Seismic design and evaluation of industrial facilities T2 - The Third European Conference on Earthquake Engineering and Seismology N2 - Industrial facilities must be thoroughly designed to withstand seismic actions as they exhibit an increased loss potential due to the possibly wideranging damage consequences and the valuable process engineering equipment. Past earthquakes showed the social and political consequences of seismic damage to industrial facilities and sensitized the population and politicians worldwide for the possible hazard emanating from industrial facilities. However, a holistic approach for the seismic design of industrial facilities can presently neither be found in national nor in international standards. The introduction of EN 1998-4 of the new generation of Eurocode 8 will improve the normative situation with specific seismic design rules for silos, tanks and pipelines and secondary process components. The article presents essential aspects of the seismic design of industrial facilities based on the new generation of Eurocode 8 using the example of tank structures and secondary process components. The interaction effects of the process components with the primary structure are illustrated by means of the experimental results of a shaking table test of a three story moment resisting steel frame with different process components. Finally, an integrated approach of digital plant models based on building information modelling (BIM) and structural health monitoring (SHM) is presented, which provides not only a reliable decision-making basis for operation, maintenance and repair but also an excellent tool for rapid assessment of seismic damage. KW - Industrial facilities KW - Seismic design KW - Tanks KW - EN 1998-4 KW - Structural health monitoring Y1 - 2022 SN - 978-3-031-15103-3 SN - 978-3-031-15106-4 SN - 978-3-031-15104-0 U6 - https://doi.org/10.1007/978-3-031-15104-0 SN - 2524-342X SN - 2524-3438 N1 - 3ECEES - Third European Conference on Earthquake Engineering and Seismology, September 4 – September 9, 2022, Bucharest SP - 449 EP - 464 PB - Springer CY - Cham ER - TY - CHAP A1 - Czarnecki, Christian ED - vom Brocke, Jan ED - Mendling, Jan T1 - Establishment of a central process governance organization combined with operational process improvements : Insights from a BPM Project at a leading telecommunications operator in the Middle East T2 - Business process management cases : digital innovation and business transformation in practice N2 - Because of customer churn, strong competition, and operational inefficiencies, the telecommunications operator ME Telco (fictitious name due to confidentiality) launched a strategic transformation program that included a Business Process Management (BPM) project. Major problems were silo-oriented process management and missing cross-functional transparency. Process improvements were not consistently planned and aligned with corporate targets. Measurable inefficiencies were observed on an operational level, e.g., high lead times and reassignment rates of the incident management process. Y1 - 2018 SN - 978-3-319-58306-8 SN - 978-3-319-58307-5 SN - 978-3-319-86372-6 U6 - https://doi.org/10.1007/978-3-319-58307-5 N1 - Als Präsenzexemplar unter der Signatur 20 PZR 469-1 vorhanden. SP - 57 EP - 76 PB - Springer CY - Cham ER - TY - JOUR T1 - Dimensionen 1-2016 : Magazin der FH Aachen University of Applied Sciences N2 - Inhalt 06 Fast jeder Zweite ist betroffen | Psychosoziale Beratung hilft Studierenden 10 Hacken statt Knacken | IT-Sicherheit im Automobil: Kooperation der FH Aachen mit Interpol 13 Dritter Platz für die FH Aachen beim PR-Bild Award 14 Ich bin ein Berlinger | Tourbus Wolfgang chauffiert keine Rockstars, sondern 3D-Drucker 18 Licht aus, Spot an und ... studieren | Fachbereich Wirtschaftswissenschaften dreht Imagefilm 22 Ein Tropfen Blut genügt | FH-Absolventen forschen in Grundlagenprojekt zu mobilen Geräten, die Malaria diagnostizieren können 24 Die dritte Hand | Babor setzt "Pick-by-Vision"-Datenbrille als weltweit erstes Unternehmen ein - FH-Forscher Prof. Voß war an der Entwicklung beteiligt 30 3 Fragen an den neuen AStA-Vorsitzenden Paul Baumann 32 Maronen-Creme-Suppe 34 Schmerzfrei!? | FH-Mitarbeiter Herbert Meurers war schon tot - und kämpfte sich zurück ins Leben 40 Mit "Sally" über die Weichen | Schienenfahrzeugtechnik an der FH Aachen 44 Sicherheit, Freiheit - und Freude über die Bürokratie | Der Syrer Hasan al Jalloud studiert an der FH Aachen und blickt mit Sorge auf das Geschehen in seinem Heimatland 46 Diese Frau erfüllt keine Klischees | Ana Pérez ist die einzige Frau im Aixtreme-Racing-Team 50 Des Rätsels Lösung: das Bewahren | Gespräch mit Prof. Dr. Heinrich Hemme zum Thema Unterhaltungsmathematik 54 "Da weiß man einfach, was Sache ist" | Bauunternehmer Hubert Schlun über sein Leben, seine Werte, seine FH Aachen 58 Prof. Baumann ist neuer LRK-Vorsitzender | FH-Rektor macht sich für die Fachhochschulen in NRW stark 60 Lehrer mit einem Herz für Holz | Alexander Forbrig nimmt am BeLEK-Programm teil und verbindet sein Studium mit einer Ausbildung zum Berufsschullehrer 63 Impressum T3 - Dimensionen - Magazin der FH Aachen University of Applied Sciences - 2016, 1 Y1 - 2016 CY - Aachen ER - TY - JOUR T1 - Dimensionen 2-2016 : Magazin der FH Aachen University of Applied Sciences N2 - Inhalt 06 Von Aachen nach Hollywood | Am 5. März 2016 lädt Shawn Bu den Star-Wars-Fanfilm, den er für seine Bachelorarbeit produziert hat, bei YouTube hoch. Was dann passiert, ist einfach unglaublich 16 Es geht aufwärts | FH entwickelt Kletterroboter zur Wartung und Reparatur von Windenergieanlagen 20 Auf den Millimeter genau | FH-Bauingenieure vermessen die Urftstaumauer 24 Auf legendären Rennstrecken | FH-Youngster treten in GT-Motorsportserie an 26 "Unten ist da, wo die Erde ist..." | Astronaut Dr. Thomas Reiter trägt an der FH Aachen vor 30 Von der Kita entspannt in den Hörsaal | Wie man den Spagat zwischen Kindererziehung und Studium meistert 32 "Solidarität ist keine Rosinenpickerei" | Martin Schulz und der Spiegel zu Gast an der FH Aachen 34 Ankommen | Drei Beispiele, wie Menschen an der FH Aachen und in der Region sich mit dem Thema Flucht beschäftigen 36 "Wir sind nicht die großen Retter" | Fotodokumentation von Stephan Klumpp 38 Mehr als nur ein Dach über dem Kopf | Dina Bharucha entwickelt ein ausklappbares Flüchlingshaus 40 "Es wird zu wenig über Fluchtursachen gesprochen" | Knut Paul, Pressesprecher der Bundespolizeiinspektion Aachen, über die Flüchtlingslage in der Aachener Region 42 Pinipas Abenteuer | Eine himmlische Pfannkuchensuche durch Europa 44 Warum es sich lohnt, in Nachwuchs zu investieren | Drei Beispiele aus dem FH-Stipendienprogramm 46 Rückenschmerzen ade | Das Start-up-Unternehmen physiosense entwickelt einen "intelligenten" Bürostuhl 48 Fahren und sparen | FH-Wissenschaftler Jörg Kreyer erforscht, wie der Kraftstoffverbrauch von Nutzfahrzeugen gesenkt werden kann 52 Informationsdesign für die Industrie 4.0 | "ProSense": Fachbereich Gestaltung entwickelt neues Verfahren zur visuellen Darstellung großer Datenmengen 58 Maßgeschneidert für unsere Region | Der Studiengang "Open Borders MBA" richtet sich an Führungskräfte, die grenzüberschreitend arbeiten wollen 60 Rennsport im Miniaturformat| FH unterstützt das Einhard-Gymnasium bei der Junior-Ingenieur-Akademie 61 Mathematik der Herzen 63 Impressum T3 - Dimensionen - Magazin der FH Aachen University of Applied Sciences - 2016, 2 Y1 - 2016 CY - Aachen ER - TY - BOOK A1 - Gebhardt, Andreas A1 - Kessler, Julia A1 - Thurn, Laura T1 - 3D-Drucken: Grundlagen und Anwendungen des additive manufacturing (AM) Y1 - 2016 SN - 978-3-446-44672-4 U6 - https://doi.org/10.3139/9783446448452 PB - Hanser CY - München ET - 2., neu bearbeitete und erweiterte Auflage ER - TY - JOUR A1 - Levers, A. A1 - Staat, Manfred A1 - Laack, Walter van T1 - Analysis of the long-term effect of the MBST® nuclear magnetic resonance therapy on gonarthrosis JF - Orthopedic Practice Y1 - 2016 VL - 47 IS - 11 SP - 521 EP - 528 ER - TY - JOUR A1 - Koster, Arie A1 - Scheidweiler, Robert A1 - Tieves, Martin T1 - A flow based pruning scheme for enumerative equitable coloring algorithms JF - A flow based pruning scheme for enumerative equitable coloring algorithms N2 - An equitable graph coloring is a proper vertex coloring of a graph G where the sizes of the color classes differ by at most one. The equitable chromatic number is the smallest number k such that G admits such equitable k-coloring. We focus on enumerative algorithms for the computation of the equitable coloring number and propose a general scheme to derive pruning rules for them: We show how the extendability of a partial coloring into an equitable coloring can be modeled via network flows. Thus, we obtain pruning rules which can be checked via flow algorithms. Computational experiments show that the search tree of enumerative algorithms can be significantly reduced in size by these rules and, in most instances, such naive approach even yields a faster algorithm. Moreover, the stability, i.e., the number of solved instances within a given time limit, is greatly improved. Since the execution of flow algorithms at each node of a search tree is time consuming, we derive arithmetic pruning rules (generalized Hall-conditions) from the network model. Adding these rules to an enumerative algorithm yields an even larger runtime improvement. Y1 - 2016 U6 - https://doi.org/10.48550/arXiv.1607.08754 N1 - Lehrstuhl II für Mathematik, RWTH Aachen University SP - 1 EP - 30 ER - TY - JOUR A1 - Beckenbach, Isabel A1 - Scheidweiler, Robert T1 - Perfect ƒ-Matchings and ƒ-Factors in Hypergraphs - A Combinatorial Approach JF - Discrete Mathematics N2 - We prove characterizations of the existence of perfect ƒ-matchings in uniform mengerian and perfect hypergraphs. Moreover, we investigate the ƒ-factor problem in balanced hypergraphs. For uniform balanced hypergraphs we prove two existence theorems with purely combinatorial arguments, whereas for non-uniform balanced hypergraphs we show that the ƒ-factor problem is NP-hard. Y1 - 2016 U6 - https://doi.org/10.1016/j.disc.2017.05.005 SN - 2192-7782 N1 - Als Volltext auch bei ZIB (Zuse Institute Berlin) VL - 240 IS - 10 SP - 2499 EP - 2506 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Scheidweiler, Robert A1 - Triesch, Eberhard T1 - A note on the duality between matchings and vertex covers in balanced hypergraphs JF - Journal of Combinatorial Optimization N2 - We present a new Min-Max theorem for an optimization problem closely connected to matchings and vertex covers in balanced hypergraphs. The result generalizes Kőnig’s Theorem (Berge and Las Vergnas in Ann N Y Acad Sci 175:32–40, 1970; Fulkerson et al. in Math Progr Study 1:120–132, 1974) and Hall’s Theorem (Conforti et al. in Combinatorica 16:325–329, 1996) for balanced hypergraphs. KW - Hall’s Theorem KW - Koenig’s Theorem KW - Duality KW - Balanced hypergraph KW - Hypergraph KW - Vertex cover KW - Matching Y1 - 2016 U6 - https://doi.org/10.1007/s10878-015-9887-5 SN - 1573-2886 N1 - Lehrstuhl II für Mathematik RWTH Aachen VL - 32 IS - 2 SP - 639 EP - 644 PB - Springer CY - Berlin ER - TY - JOUR A1 - Niedermeyer, Angela A1 - Zhou, Bei A1 - Dursun, Gözde A1 - Temiz Artmann, Aysegül A1 - Markert, Bernd T1 - An examination of tissue engineered scaffolds in a bioreactor JF - Proceedings in Applied Mathematics and Mechanics PAMM N2 - Replacement tissues, designed to fill in articular cartilage defects, should exhibit the same properties as the native material. The aim of this study is to foster the understanding of, firstly, the mechanical behavior of the material itself and, secondly, the influence of cultivation parameters on cell seeded implants as well as on cell migration into acellular implants. In this study, acellular cartilage replacement material is theoretically, numerically and experimentally investigated regarding its viscoelastic properties, where a phenomenological model for practical applications is developed. Furthermore, remodeling and cell migration are investigated. Y1 - 2016 U6 - https://doi.org/10.1002/pamm.201610038 SN - 1617-7061 N1 - Joint Annual Meeting of DMV and GAMM 2016, 87th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM) and Deutsche Mathematiker-Vereinigung (DMV), Braunschweig, DE, Mar 7-11, 2016 VL - 16 IS - 1 SP - 99 EP - 100 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Kilic, S. A. A1 - Raatschen, Hans-Jürgen A1 - Körfgen, B. A1 - Apaydin, N. M. A1 - Astaneh-Asl, A. T1 - FE Model of the Fatih Sultan Mehmet Suspension Bridge Using Thin Shell Finite Elements JF - Arabian Journal for Science and Engineering N2 - This paper presents the results of an eigenvalue analysis of the Fatih Sultan Mehmet Bridge. A high-resolution finite element model was created directly from the available design documents. All physical properties of the structural components were included in detail, so no calibration to the measured data was necessary. The deck and towers were modeled with shell elements. A nonlinear static analysis was performed before the eigenvalue calculation. The calculated natural frequencies and corresponding mode shapes showed good agreement with the available measured ambient vibration data. The calculation of the effective modal mass showed that nine modes had single contributions higher than 5 % of the total mass. They were in a frequency range up to 1.2 Hz. The comparison of the results for the torsional modes especially demonstrated the advantage of using thin shell finite elements over the beam modeling approach. KW - Suspension bridge KW - 3D nonlinear finite element model KW - Thin shell finite elements KW - Natural frequency KW - Effective modal mass Y1 - 2017 U6 - https://doi.org/10.1007/s13369-016-2316-y SN - 2191-4281 VL - 42 IS - 3 SP - 1103 EP - 1116 PB - Springer Nature ER - TY - CHAP A1 - Heuermann, Holger A1 - Sadeghfam, Arash T1 - Analog Amplitude-Locked Loop Circuit to Support RF Energy Solutions T2 - IEEE MTT-S International Microwave Symposium Digest Y1 - 2016 SN - 978-150900698-4 U6 - https://doi.org/10.1109/MWSYM.2016.7540092 ER - TY - JOUR A1 - Dantism, Shahriar A1 - Takenaga, Shoko A1 - Wagner, Torsten A1 - Wagner, Patrick A1 - Schöning, Michael Josef T1 - Differential imaging of the metabolism of bacteria and eukaryotic cells based on light-addressable potentiometric sensors JF - Electrochimica Acta N2 - A light-addressable potentiometric sensor (LAPS) is a field-effect-based potentiometric sensor with an electrolyte/insulator/semiconductor (EIS) structure, which is able to monitor analyte concentrations of (bio-)chemical species in aqueous solutions in a spatially resolved way. Therefore, it is also an appropriate tool to record 2D-chemical images of concentration variations on the sensor surface. In the present work, two differential, LAPS-based measurement principles are introduced to determine the metabolic activity of Escherichia coli (E. coli) K12 and Chinese hamster ovary (CHO) cells as test microorganisms. Hereby, we focus on i) the determination of the extracellular acidification rate (ΔpH/min) after adding glucose solutions to the cell suspensions; and ii) recording the amplitude increase of the photocurrent (Iph) related to the produced acids from E. coli K12 bacteria and CHO cells on the sensor surface by 2D-chemical imaging. For this purpose, 3D-printed multi-chamber structures were developed and mounted on the planar sensor-chip surface to define four independent compartments, enabling differential measurements with varying cell concentrations. The differential concept allows eliminating unwanted drift effects and, with the four-chamber structures, measurements on the different cell concentrations were performed simultaneously, thus reducing also the overall measuring time. Y1 - 2017 U6 - https://doi.org/10.1016/j.electacta.2017.05.196 SN - 0013-4686 VL - 246 SP - 234 EP - 241 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Jildeh, Zaid B. A1 - Kirchner, Patrick A1 - Oberländer, Jan A1 - Kremers, Alexander A1 - Wagner, Torsten A1 - Wagner, Patrick H. A1 - Schöning, Michael Josef T1 - FEM-based modeling of a calorimetric gas sensor for hydrogen peroxide monitoring JF - physica status solidi a : applications and materials sciences N2 - A physically coupled finite element method (FEM) model is developed to study the response behavior of a calorimetric gas sensor. The modeled sensor serves as a monitoring device of the concentration of gaseous hydrogen peroxide (H2 O2) in a high temperature mixture stream in aseptic sterilization processes. The principle of operation of a calorimetric H2 O2 sensor is analyzed and the results of the numerical model have been validated by using previously published sensor experiments. The deviation in the results between the FEM model and experimental data are presented and discussed. Y1 - 2017 U6 - https://doi.org/10.1002/pssa.201600912 SN - 1862-6319 IS - Early View PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Molinnus, Denise A1 - Poghossian, Arshak A1 - Keusgen, Michael A1 - Katz, Evgeny A1 - Schöning, Michael Josef T1 - Coupling of Biomolecular Logic Gates with Electronic Transducers: From Single Enzyme Logic Gates to Sense/Act/Treat Chips JF - Electroanalysis N2 - The integration of biomolecular logic principles with electronic transducers allows designing novel digital biosensors with direct electrical output, logically triggered drug-release, and closed-loop sense/act/treat systems. This opens new opportunities for advanced personalized medicine in the context of theranostics. In the present work, we will discuss selected examples of recent developments in the field of interfacing enzyme logic gates with electrodes and semiconductor field-effect devices. Special attention is given to an enzyme OR/Reset logic gate based on a capacitive field-effect electrolyte-insulator-semiconductor sensor modified with a multi-enzyme membrane. Further examples are a digital adrenaline biosensor based on an AND logic gate with binary YES/NO output and an integrated closed-loop sense/act/treat system comprising an amperometric glucose sensor, a hydrogel actuator, and an insulin (drug) sensor. Y1 - 2017 U6 - https://doi.org/10.1002/elan.201700208 SN - 1521-4109 VL - 29 IS - 8 SP - 1840 EP - 1849 PB - Wiley CY - Weinheim ER -