TY  - JOUR
A1  - Sagymbay, Altynay
A1  - G.E., Nusupbaeva
A1  - N.Zh, Tleumbetova
A1  - A.S., Mutalieva
A1  - Nurpeisova, Ainur
A1  - D.B., Jussupova
A1  - Digel, Ilya
T1  - Molecular genetics features of the epidemic season 2017-2018 on the influenza in Kazakhstan
JF  - Eurasian Journal of  Ecology
Y1  - 2019
SN  - 2617-7358
VL  - 58
IS  - 1
SP  - 50
EP  - 60
ER  - 
TY  - JOUR
A1  - Albanna, Walid
A1  - Lüke, Jan Niklas
A1  - Schubert, Gerrit Alexander
A1  - Dibué-Adjei, Maxine
A1  - Kotliar, Konstantin
A1  - Hescheler, Jürgen
A1  - Clusmann, Hans
A1  - Steiger, Hans-Jakob
A1  - Hänggi, Daniel
A1  - Kamp, Marcel A.
A1  - Schneider, Toni
A1  - Neumaier, Felix
T1  - Modulation of Ca v 2.3 channels by unconjugated bilirubin (UCB) – Candidate mechanism for UCB-induced neuromodulation and neurotoxicity
JF  - Molecular and Cellular Neuroscience
Y1  - 2019
U6  - https://doi.org/10.1016/j.mcn.2019.03.003
SN  - 1044-7431
VL  - 96
IS  - 4
SP  - 35
EP  - 46
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Raman, Aravind Hariharan
A1  - Jung, Alexander
A1  - Horváth, András
A1  - Becker, Nadine
A1  - Staat, Manfred
ED  - Staat, Manfred
ED  - Erni, Daniel
T1  - Modification of a computer model of human stem cell-derived cardiomyocyte electrophysiology based on Patch-Clamp measurements
T2  - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen
N2  - Human induced pluripotent stem cells (hiPSCs) have shown to be promising in disease studies and drug screenings [1]. Cardiomyocytes derived from hiPSCs have been extensively investigated using patch-clamping and optical methods to compare their electromechanical behaviour relative to fully matured adult cells. Mathematical models can be used for translating findings on hiPSCCMs to adult cells [2] or to better understand the mechanisms of various ion channels when a drug is applied [3,4]. Paci et al. (2013) [3] developed the first model of hiPSC-CMs, which they later refined based on new data [3]. The model is based on iCells® (Fujifilm Cellular Dynamics, Inc. (FCDI), Madison WI, USA) but major differences among several cell lines and even within a single cell line have been found and motivate an approach for creating sample-specific models. We have developed an optimisation algorithm that parameterises the conductances (in S/F=Siemens/Farad) of the latest Paci et al. model (2018) [5] using current-voltage data obtained in individual patch-clamp experiments derived from an automated patch clamp system (Patchliner, Nanion Technologies GmbH, Munich).
Y1  - 2019
SN  - 978-3-940402-22-6
U6  - https://doi.org/10.17185/duepublico/48750
SP  - 10
EP  - 11
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - JOUR
A1  - Jung, Alexander
A1  - Staat, Manfred
T1  - Modeling and simulation of human induced pluripotent stem cell-derived cardiac tissue
JF  - GAMM - Mitteilungen der Gesellschaft für Angewandte Mathematik und Mechanik
Y1  - 2019
U6  - https://doi.org/10.1002/gamm.201900002
SN  - 1522-2608
VL  - 42
IS  - 4
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Campen, R.
A1  - Kowalski, Julia
A1  - Lyons, W.B.
A1  - Tulaczyk, S.
A1  - Dachwald, Bernd
A1  - Pettit, E.
A1  - Welch, K. A.
A1  - Mikucki, J.A.
T1  - Microbial diversity of an Antarctic subglacial community and high‐resolution replicate sampling inform hydrological connectivity in a polar desert
JF  - Environmental Microbiology
Y1  - 2019
U6  - https://doi.org/10.1111/1462-2920.14607
SN  - 1462-2920
IS  - accepted article
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - THES
A1  - Tran, Ngoc Trinh
T1  - Limit and Shakedown analysis of structures under stochastic conditions
Y1  - 2019
U6  - https://doi.org/10.24355/dbbs.084-201902121135-0
PB  - Technische Universität Braunschweig
CY  - Braunschweig
ER  - 
TY  - JOUR
A1  - Meyer, Carolin
A1  - Gaalen, Kerstin van
A1  - Leschinger, Tim
A1  - Scheyerer, Max J.
A1  - Neiss, Wolfram F.
A1  - Staat, Manfred
A1  - Müller, Lars P.
A1  - Wegmann, Kilian
T1  - Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement
JF  - BioMed Research International
Y1  - 2019
U6  - https://doi.org/10.1155/2019/9232813
SP  - Article ID 9232813
ER  - 
TY  - CHAP
A1  - Ketelhut, Maike
A1  - Göll, Fabian
A1  - Braunstein, Bjoern
A1  - Albracht, Kirsten
A1  - Abel, Dirk
T1  - Iterative learning control of an industrial robot for neuromuscular training
T2  - 2019 IEEE Conference on Control Technology and Applications
N2  - Effective training requires high muscle forces potentially leading to training-induced injuries. Thus, continuous monitoring and controlling of the loadings applied to the musculoskeletal system along the motion trajectory is required. In this paper, a norm-optimal iterative learning control algorithm for the robot-assisted training is developed. The algorithm aims at minimizing the external knee joint moment, which is commonly used to quantify the loading of the medial compartment. To estimate the external knee joint moment, a musculoskeletal lower extremity model is implemented in OpenSim and coupled with a model of an industrial robot and a force plate mounted at its end-effector. The algorithm is tested in simulation for patients with varus, normal and valgus alignment of the knee. The results show that the algorithm is able to minimize the external knee joint moment in all three cases and converges after less than seven iterations.
KW  - Knee
KW  - Training
KW  - Load modeling
KW  - Force
KW  - Iterative learning control
Y1  - 2019
SN  - 978-1-7281-2767-5 (ePub)
SN  - 978-1-7281-2766-8 (USB)
SN  - 978-1-7281-2768-2 (PoD)
U6  - https://doi.org/10.1109/CCTA.2019.8920659
N1  - 2019 IEEE Conference on Control Technology and Applications (CCTA) Hong Kong, China, August 19-21, 2019
PB  - IEEE
CY  - New York
ER  - 
TY  - JOUR
A1  - Leschinger, Tim
A1  - Besch, Katharina
A1  - Aydin, Cansu
A1  - Staat, Manfred
A1  - Scaal, Martin
A1  - Müller, Lars Peter
A1  - Wegmann, Kilian
T1  - Irreparable rotator cuff tears: a biomechanical comparison of superior capsuloligamentous complex reconstruction techniques and an interposition graft technique
JF  - The Orthopaedic Journal of Sports Medicine
Y1  - 2019
U6  - https://doi.org/10.1177/2325967119864590
VL  - 7
IS  - 8
SP  - 1
EP  - 5
ER  - 
TY  - CHAP
A1  - Dachwald, Bernd
A1  - Ohndorf, Andreas
T1  - Global optimization of continuous-thrust trajectories using evolutionary neurocontrol
T2  - Modeling and Optimization in Space Engineering
N2  - Searching optimal continuous-thrust trajectories is usually a difficult and time-consuming task. The solution quality of traditional optimal-control methods depends strongly on an adequate initial guess because the solution is typically close to the initial guess, which may be far from the (unknown) global optimum. Evolutionary neurocontrol attacks continuous-thrust optimization problems from the perspective of artificial intelligence and machine learning, combining artificial neural networks and evolutionary algorithms. This chapter describes the method and shows some example results for single- and multi-phase continuous-thrust trajectory optimization problems to assess its performance. Evolutionary neurocontrol can explore the trajectory search space more exhaustively than a human expert can do with traditional optimal-control methods. Especially for difficult problems, it usually finds solutions that are closer to the global optimum. Another fundamental advantage is that continuous-thrust trajectories can be optimized without an initial guess and without expert supervision.
Y1  - 2019
SN  - 978-3-030-10501-3
SN  - 978-3-030-10500-6
U6  - https://doi.org/10.1007/978-3-030-10501-3_2
N1  - Springer Optimization and Its Applications, vol 144
gedruckt unter der Signatur 21 ZSS 46 in der Bereichsbibliothek Eupener Str. vorhanden
SP  - 33
EP  - 57
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Grundmann, Jan Thimo
A1  - Bauer, Waldemar
A1  - Boden, Ralf
A1  - Ceriotti, Matteo
A1  - Chand, Suditi
A1  - Cordero, Federico
A1  - Dachwald, Bernd
A1  - Dumont, Etienne
A1  - Grimm, Christian D.
A1  - Heiligers, Jeannette
A1  - Herčík, David
A1  - Hérique, Alain
A1  - Ho, Tra-Mi
A1  - Jahnke, Rico
A1  - Kofman, Wlodek
A1  - Lange, Caroline
A1  - Lichtenheldt, Roy
A1  - McInnes, Colin
A1  - Meß, Jan-Gerd
A1  - Mikschl, Tobias
A1  - Mikulz, Eugen
A1  - Montenegro, Sergio
A1  - Moore, Iain
A1  - Pelivan, Ivanka
A1  - Peloni, Alessandro
A1  - Plettemeier, Dirk
A1  - Quantius, Dominik
A1  - Reershemius, Siebo
A1  - Renger, Thomas
A1  - Riemann, Johannes
A1  - Rogez, Yves
A1  - Ruffer, Michael
A1  - Sasaki, Kaname
A1  - Schmitz, Nicole
A1  - Seboldt, Wolfgang
A1  - Seefeldt, Patric
A1  - Spietz, Peter
A1  - Spröwitz, Tom
A1  - Sznajder, Maciej
A1  - Tóth, Norbert
A1  - Vergaaij, Merel
A1  - Viavattene, Giulia
A1  - Wejmo, Elisabet
A1  - Wiedemann, Carsten
A1  - Wolff, Friederike
A1  - Ziach, Christian
T1  - Flights are ten a sail – Re-use and commonality in the design and system engineering of small spacecraft solar sail missions with modular hardware for responsive and adaptive exploration
T2  - 70th International Astronautical Congress (IAC)
KW  - system engineering
KW  - small solar system body characterisation
KW  - small spacecraft solar sail
KW  - small spacecraft asteroid lander
KW  - responsive space
Y1  - 2019
SN  - 9781713814856
N1  - 70th International Astronautical Congress (IAC), Washington D.C., United States, 21-25 October 2019
SP  - 1
EP  - 7
ER  - 
TY  - JOUR
A1  - Werkhausen, Amelie
A1  - Cronin, Neil J.
A1  - Albracht, Kirsten
A1  - Bojsen-Møller, Jens
A1  - Seynnes, Olivier R.
T1  - Distinct muscle-tendon interaction during running at different speeds and in different loading conditions
JF  - Journal of Applied Physiology
Y1  - 2019
U6  - https://doi.org/10.1152/japplphysiol.00710.2018
SN  - 1522-1601
VL  - 127
IS  - 1
SP  - 246
EP  - 253
ER  - 
TY  - CHAP
A1  - Hunker, Jan
A1  - Jung, Alexander
A1  - Goßmann, Matthias
A1  - Linder, Peter
A1  - Staat, Manfred
ED  - Staat, Manfred
ED  - Erni, Daniel
T1  - Development of a tool to analyze the conduction speed in microelectrode array measurements of cardiac tissue
T2  - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH Aachen
N2  - The discovery of human induced pluripotent stem cells reprogrammed from somatic cells [1] and their ability to differentiate into cardiomyocytes (hiPSC-CMs) has provided a robust platform for drug screening [2]. Drug screenings are essential in the development of new components, particularly for evaluating the potential of drugs to induce life-threatening pro-arrhythmias. Between 1988 and 2009, 14 drugs have been removed from the market for this reason [3]. The microelectrode array (MEA) technique is a robust tool for drug screening as it detects the field potentials (FPs) for the entire cell culture. Furthermore, the propagation of the field potential can be examined on an electrode basis. To analyze MEA measurements in detail, we have developed an open-source tool.
Y1  - 2019
SN  - 978-3-940402-22-6
U6  - https://doi.org/10.17185/duepublico/48750
SP  - 7
EP  - 8
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - JOUR
A1  - Malik, A. M.
A1  - Abdieva, G. Zh.
A1  - Ualieva, P. S.
A1  - Zhubanova, A. A.
A1  - Temiz Artmann, Aysegül
T1  - CКPИНИНГ МИКPOOPГAНИЗМOВ-ДECТPУКТOPOВ XЛOРOPГAНИЧECКИX ЗAГPЯЗНИТEЛEЙ
T1  - Screening of microorganisms – destructors of chlororganic pollutants
JF  - Eurasian Journal of Ecology
Y1  - 2019
SN  - 2617-7358
VL  - 61
IS  - 4
SP  - 61
EP  - 71
ER  - 
TY  - JOUR
A1  - Schieren, Mark
A1  - Kleinschmidt, Joris
A1  - Schmutz, Axel
A1  - Loop, Torsten
A1  - Gatzweiler, Karl-Heinz
A1  - Staat, Manfred
A1  - Wappler, Frank
A1  - Defosse, Jerome
T1  - Comparison of forces acting on maxillary incisors during tracheal intubation with different laryngoscopy techniques: a blinded manikin study
JF  - Anaesthesia
Y1  - 2019
SN  - 1365-2044
U6  - https://doi.org/10.1111/anae.14815
N1  - Die Anhänge "Table S1 (Impact of sex and level of training on dental force. Results presented as median (IQR [range]) and n (%))" und 
"Appendix S1 (Measurement technique.)" stehen unter "Supporting Information" zum Download bereit.
VL  - 74
IS  - 12
PB  - Wiley-Blackwell
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Jan Thimo, Grundmann
A1  - Bauer, Waldemar
A1  - Biele, Jens
A1  - Boden, Ralf
A1  - Ceriotti, Matteo
A1  - Cordero, Federico
A1  - Dachwald, Bernd
A1  - Dumont, Etienne
A1  - Grimm, Christian D.
A1  - Hercik, David
T1  - Capabilities of Gossamer-1 derived small spacecraft solar sails carrying Mascot-derived nanolanders for in-situ surveying of NEAs
JF  - Acta Astronautica
Y1  - 2019
U6  - https://doi.org/10.1016/j.actaastro.2018.03.019
SN  - 0094-5765
VL  - 156
IS  - 3
SP  - 330
EP  - 362
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - PAT
A1  - Staat, Manfred
A1  - Horbach, Andreas
A1  - Gatzweiler, Karl-Heinz
T1  - Biaxiales Materialprüfsystem und Verfahren zu dessen Anwendung
N2  - System und Verfahren zur Durchführung von Messungen biaxialer und kreuzförmiger Zugversuche, wobei ein Weg oder eine Kraft auf eine Materialprobe über mindestens zwei Nadelarme mit Nadeln geleitet wird, die in einem Gehäuse gelagert sind, wobei die Arme und/oder Nadelarme für eine ungehinderte Querkontraktion bei gleichmäßiger Lasteinleitung um eine Achse drehbar gelagert und seitlich auslenkbar sind.
Y1  - 2019
N1  - Patent DE102017116067
ER  - 
TY  - JOUR
A1  - Ermolaev, AP
A1  - Erichev, VP
A1  - Antonov, AA
A1  - Grigoryan, GL
A1  - Kotliar, Konstantin
A1  - Levitsky, YV
A1  - Hderi, K
A1  - Mazurova, YV
T1  - Assessing retinal photosensitivity in patients with central vision impairment using a portable perimeter (a preliminary report)
JF  - Vestnik oftalmologii
Y1  - 2019
U6  - https://doi.org/10.17116/oftalma201913503146
N1  - Abstract in Englisch
VL  - 135
IS  - 3
SP  - 46
EP  - 54
ER  - 
TY  - JOUR
A1  - Savitskaya, I.S.
A1  - Kistaubayeva, A.S.
A1  - Ignatova, L.V.
A1  - Digel, Ilya
T1  - Antimicrobial and wound healing properties of a bacterial cellulose based material containing B. subtilis cells
JF  - Heliyon
Y1  - 2019
U6  - https://doi.org/10.1016/j.heliyon.2019.e02592
SN  - 2405-8440
VL  - 5
IS  - 10
SP  - Artikelnummer e02592
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Schael, S.
A1  - Atanasyan, A.
A1  - Berdugo, J.
A1  - Bretz, T.
A1  - Czupalla, Markus
A1  - Dachwald, Bernd
A1  - Doetinchem, P. von
A1  - Duranti, M.
A1  - Gast, H.
A1  - Karpinski, W.
A1  - Kirn, T.
A1  - Lübelsmeyer, K.
A1  - Maña, C.
A1  - Marrocchesi, P.S.
A1  - Mertsch, P.
A1  - Moskalenko, I.V.
A1  - Schervan, T.
A1  - Schluse, M.
A1  - Schröder, K.-U.
A1  - Schultz von Dratzig, A.
A1  - Senatore, C.
A1  - Spies, L.
A1  - Wakely, S.P.
A1  - Wlochal, M.
A1  - Uglietti, D.
A1  - Zimmermann, J.
T1  - AMS-100: The next generation magnetic spectrometer in space – An international science platform for physics and astrophysics at Lagrange point 2
JF  - Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Y1  - 2019
U6  - https://doi.org/10.1016/j.nima.2019.162561
SN  - 0168-9002
VL  - 944
IS  - 162561
PB  - Elsevier
CY  - Amsterdam
ER  -