TY - JOUR A1 - Kopp, Alexander A1 - Schmeets, Ralf A1 - Gosau, Martin A1 - Friedrich, Reinhard E. A1 - Fuest, Sandra A1 - Behbahani, Mehdi A1 - Barbeck, Mike A1 - Rutkowski, Rico A1 - Burg, Simon A1 - Kluwe, Lan A1 - Henningsen, Anders T1 - Production and Characterization of Porous Fibroin Scaffolds for Regenerative Medical Application JF - In Vivo Y1 - 2019 U6 - http://dx.doi.org/10.21873/invivo.11536 SN - 1791-7549 VL - 33 IS - 3 SP - 757 EP - 762 ER - TY - CHAP A1 - Bayer, Robin A1 - Hescheler, Jürgen A1 - Artmann, Gerhard A1 - Temiz Artmann, Aysegül ED - Staat, Manfred ED - Erni, Daniel T1 - Treating arterial hypertension in a cell culture well T2 - 3rd YRA MedTech Symposium 2019 : May 24 / 2019 / FH AachenW N2 - Hypertension describes the pathological increase of blood pressure, which is most commonly associated with the increase of vascular wall stiffness [1]. Referring to the “Deutsche Bluthochdruck Liga” this pathology shows a growing trend in our aging society. In order to find novel pharmacological and probably personalized treatments, we want to present a functional approach to study biomechanical properties of a human aortic vascular model. In this method review we will give an overview of recent studies which were carried out with the CellDrum technology [2] and underline the added value to already existing standard procedures known from the field of physiology. Herein described CellDrum technology is a system to measure functional mechanical properties of cell monolayers and thin tissue constructs in-vitro. Additionally, the CellDrum enables to elucidate the mechanical response of cells to pharmacological drugs, toxins and vasoactive agents. Due to its highly flexible polymer support, cells can also be mechanically stimulated by steady and cyclic biaxial stretching. Y1 - 2019 SN - 978-3-940402-22-6 U6 - http://dx.doi.org/10.17185/duepublico/48750 SP - 5 EP - 6 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - JOUR A1 - Krome, Cornelia A1 - Höft, Jan A1 - Sander, Volker T1 - Clustering time series applied to energy markets JF - Energy Informatics Y1 - 2019 U6 - http://dx.doi.org/10.1186/s42162-019-0076-0 SN - 2520-8942 VL - 2 IS - Article numer 17 SP - 1 EP - 20 PB - Springer CY - Berlin ER - TY - JOUR A1 - Orzada, Stephan A1 - Solbach, Klaus A1 - Gratz, Marcel A1 - Brunheim, Sascha A1 - Fiedler, Thomas M. A1 - Johst, Sören A1 - Bitz, Andreas A1 - Shooshtary, Samaneh A1 - Abuelhaija, Asjraf A1 - Voelker, Maximilian N. A1 - Rietsch, Stefan H. G. A1 - Kraff, Oliver A1 - Maderwald, Stefan A1 - Flöser, Martina A1 - Oehmingen, Mark A1 - Quick, Harald H. A1 - Ladd, Mark E. T1 - A 32-channel parallel transmit system add-on for 7T MRI JF - Plos one Y1 - 2019 U6 - http://dx.doi.org/10.1371/journal.pone.0222452 ER - TY - CHAP A1 - Götten, Falk A1 - Finger, Felix A1 - Havermann, Marc A1 - Braun, Carsten A1 - Marino, Matthew A1 - Bil, Cees T1 - A highly automated method for simulating airfoil characteristics at low Reynolds number using a RANS - transition approach T2 - Deutscher Luft- und Raumfahrtkongress - DLRK 2019. Darmstadt, Germany Y1 - 2019 U6 - http://dx.doi.org/10.25967/490026 SP - 1 EP - 14 ER - TY - CHAP A1 - Finger, Felix A1 - Götten, Falk A1 - Braun, Carsten A1 - Bil, Cees T1 - Mass, Primary Energy, and Cost - The Impact of Optimization Objectives on the Initial Sizing of Hybrid-Electric General Aviation Aircraft T2 - Deutscher Luft- und Raumfahrtkongress 2019, DLRK 2019. Darmstadt, Germany Y1 - 2019 U6 - http://dx.doi.org/10.25967/490012 SP - 1 EP - 17 ER - TY - CHAP A1 - Götten, Falk A1 - Finger, Felix T1 - Conceptual Design of a Modular 150 kg Vertical Take-off and Landing Unmanned Aerial Vehicle T2 - Deutscher Luft- und Raumfahrtkongress - DLRK 2019. Darmstadt, Germany Y1 - 2019 SP - 1 EP - 10 ER - TY - JOUR A1 - Bhattarai, Aroj A1 - Staat, Manfred T1 - A computational study of organ relocation after laparoscopic pectopexy to repair posthysterectomy vaginal vault prolapse JF - Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization Y1 - 2019 U6 - http://dx.doi.org/10.1080/21681163.2019.1670095 SN - 2168-1171 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Noureddine, Yacine A1 - Kraff, Oliver A1 - Ladd, Mark E. A1 - Wrede, Karsten A1 - Chen, Bixia A1 - Quick, Harald H. A1 - Schaefers, Georg A1 - Bitz, Andreas T1 - Radiofrequency induced heating around aneurysm clips using a generic birdcage head coil at 7 Tesla under consideration of the minimum distance to decouple multiple aneurysm clips JF - Magnetic Resonance in Medicine Y1 - 2019 U6 - http://dx.doi.org/10.1002/mrm.27835 SN - 1522-2594 IS - Early view SP - 1 EP - 17 PB - Wiley CY - Weinheim ER - TY - CHAP A1 - Ernhardt, Selina A1 - Drumm, Christian A1 - van Gog, Tamara A1 - Brand-Gruwel, Saskia A1 - Jarodzka, Halszka T1 - Through the eyes of a programmer : a research project on how to foster programming education with eye-tracking technology T2 - Tagungsband zur 32. AKWI-Jahrestagung vom 15.09.2019 bis 18.09.2019 an der Fachhochschule für Angewandte Wissenschaften Aachen Y1 - 2019 SN - 978-3-944330-62-4 SP - 42 EP - 47 PB - Mana-Buch CY - Heide ER - TY - CHAP A1 - Hailer, Benjamin A1 - Weber, Tobias A1 - Arent, Jan-Christoph T1 - Manufacturing Process Simulation for Autoclave-Produced Sandwich Structures T2 - Proceedings of SAMPE Europe Conference 2019, Nantes, France Y1 - 2019 SP - 1 EP - 8 ER - TY - CHAP A1 - Weber, Tobias A1 - Englhard, Markus A1 - Hailer, Benjamin A1 - Arent, Jan-Christoph T1 - Manufacturing Process Simulation for the Prediction of Tool-Part-Interaction and Ply Wrinkling T2 - Proceedings of SAMPE Europe Conference 2019, Nantes, France Y1 - 2019 SP - 1 EP - 10 ER - TY - JOUR A1 - Schiedermeier, Maximilian A1 - Rettner, Cornelius A1 - Heilmann, Marcel A1 - Schneider, Felix A1 - Marz, Martin T1 - Interference of automotive HV-DC-systems by traction voltage-source-inverters (VSI) JF - 2019 IEEE Transportation Electrification Conference (ITEC-India) Y1 - 2019 U6 - http://dx.doi.org/10.1109/ITEC-India48457.2019.ITECINDIA2019-37 SP - 1 EP - 6 PB - IEEE CY - New York ER - TY - JOUR A1 - Kunkel, Maximilian Hugo A1 - Gebhardt, Andreas A1 - Mpofu, Khumbulani A1 - Kallweit, Stephan T1 - Quality assurance in metal powder bed fusion via deep-learning-based image classification JF - Rapid Prototyping Journal Y1 - 2019 U6 - http://dx.doi.org/10.1108/RPJ-03-2019-0066 SN - 1355-2546 VL - 26 IS - 2 SP - 259 EP - 266 ER - TY - CHAP A1 - Leise, Philipp A1 - Altherr, Lena A1 - Simon, Nicolai A1 - Pelz, Peter F. T1 - Finding global-optimal gearbox designs for battery electric vehicles T2 - Optimization of complex systems - theory, models, algorithms and applications : WCGO 2019 N2 - In order to maximize the possible travel distance of battery electric vehicles with one battery charge, it is mandatory to adjust all components of the powertrain carefully to each other. While current vehicle designs mostly simplify the powertrain rigorously and use an electric motor in combination with a gearbox with only one fixed transmission ratio, the use of multi-gear systems has great potential. First, a multi-speed system is able to improve the overall energy efficiency. Secondly, it is able to reduce the maximum momentum and therefore to reduce the maximum current provided by the traction battery, which results in a longer battery lifetime. In this paper, we present a systematic way to generate multi-gear gearbox designs that—combined with a certain electric motor—lead to the most efficient fulfillment of predefined load scenarios and are at the same time robust to uncertainties in the load. Therefore, we model the electric motor and the gearbox within a Mixed-Integer Nonlinear Program, and optimize the efficiency of the mechanical parts of the powertrain. By combining this mathematical optimization program with an unsupervised machine learning algorithm, we are able to derive global-optimal gearbox designs for practically relevant momentum and speed requirements. KW - Powertrain KW - Gearbox KW - Optimization KW - BEV KW - WLTP Y1 - 2019 SN - 978-3-030-21802-7 U6 - http://dx.doi.org/10.1007/978-3-030-21803-4_91 SP - 916 EP - 925 PB - Springer CY - Cham ER - TY - CHAP A1 - Stenger, David A1 - Altherr, Lena A1 - Abel, Dirk T1 - Machine learning and metaheuristics for black-box optimization of product families: a case-study investigating solution quality vs. computational overhead T2 - Operations Research Proceedings 2018 N2 - In product development, numerous design decisions have to be made. Multi-domain virtual prototyping provides a variety of tools to assess technical feasibility of design options, however often requires substantial computational effort for just a single evaluation. A special challenge is therefore the optimal design of product families, which consist of a group of products derived from a common platform. Finding an optimal platform configuration (stating what is shared and what is individually designed for each product) and an optimal design of all products simultaneously leads to a mixed-integer nonlinear black-box optimization model. We present an optimization approach based on metamodels and a metaheuristic. To increase computational efficiency and solution quality, we compare different types of Gaussian process regression metamodels adapted from the domain of machine learning, and combine them with a genetic algorithm. We illustrate our approach on the example of a product family of electrical drives, and investigate the trade-off between solution quality and computational overhead. KW - Product family optimization KW - Mixed-integer nonlinear black-box optimization KW - Engineering optimization KW - Machine learning Y1 - 2019 SN - 978-3-030-18499-5 (Print) SN - 978-3-030-18500-8 (Online) U6 - http://dx.doi.org/10.1007/978-3-030-18500-8_47 SP - 379 EP - 385 PB - Springer CY - Cham ER - TY - CHAP A1 - Müller, Tim M. A1 - Altherr, Lena A1 - Ahola, Marja A1 - Schabel, Samuel A1 - Pelz, Peter F. ED - Rodrigues, H. C. T1 - Multi-Criteria optimization of pressure screen systems in paper recycling – balancing quality, yield, energy consumption and system complexity T2 - EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization N2 - The paper industry is the industry with the third highest energy consumption in the European Union. Using recycled paper instead of fresh fibers for papermaking is less energy consuming and saves resources. However, adhesive contaminants in recycled paper are particularly problematic since they reduce the quality of the resulting paper-product. To remove as many contaminants and at the same time obtain as many valuable fibres as possible, fine screening systems, consisting of multiple interconnected pressure screens, are used. Choosing the best configuration is a non-trivial task: The screens can be interconnected in several ways, and suitable screen designs as well as operational parameters have to be selected. Additionally, one has to face conflicting objectives. In this paper, we present an approach for the multi-criteria optimization of pressure screen systems based on Mixed-Integer Nonlinear Programming. We specifically focus on a clear representation of the trade-off between different objectives. Y1 - 2019 SN - 978-3-319-97773-7 U6 - http://dx.doi.org/10.1007/978-3-319-97773-7_105 N1 - EngOpt 2018 Proceedings of the 6th International Conference on Engineering Optimization. 17-19 September 2018. Lisboa, Portugal PB - Springer International Publishing CY - Basel ER - TY - CHAP A1 - Lorenz, Imke-Sophie B. A1 - Altherr, Lena A1 - Pelz, Peter F. T1 - Graph-theoretic resilience analysis of a water distribution system's topology T2 - World Congress on Resilience, Reliability and Asset Management 2019 N2 - Water suppliers are faced with the great challenge of achieving high-quality and, at the same time, low-cost water supply. In practice, the focus is set on the most beneficial maintenance measures and/or capacity adaptations of existing water distribution systems (WDS). Since climatic and demographic influences will pose further challenges in the future, the resilience enhancement of WDS, i.e. the enhancement of their capability to withstand and recover from disturbances, has been in particular focus recently. To assess the resilience of WDS, metrics based on graph theory have been proposed. In this study, a promising approach is applied to assess the resilience of the WDS for a district in a major German City. The conducted analysis provides insight into the process of actively influencing the resilience of WDS KW - Resilience Assessment KW - Graph Theory KW - Water Supply System KW - Case Study Y1 - 2019 N1 - World Congress on Resilience, Reliability and Asset Management, 28-31 July 2019. Furama Riverfront Hotel, Singapore SP - 106 EP - 109 ER - TY - CHAP A1 - Grundmann, Jan Thimo A1 - Bauer, Waldemar A1 - Boden, Ralf A1 - Ceriotti, Matteo A1 - Chand, Suditi A1 - Cordero, Federico A1 - Dachwald, Bernd A1 - Dumont, Etienne A1 - Grimm, Christian D. A1 - Heiligers, Jeannette A1 - Herčík, David A1 - Hérique, Alain A1 - Ho, Tra-Mi A1 - Jahnke, Rico A1 - Kofman, Wlodek A1 - Lange, Caroline A1 - Lichtenheldt, Roy A1 - McInnes, Colin A1 - Meß, Jan-Gerd A1 - Mikschl, Tobias A1 - Mikulz, Eugen A1 - Montenegro, Sergio A1 - Moore, Iain A1 - Pelivan, Ivanka A1 - Peloni, Alessandro A1 - Plettemeier, Dirk A1 - Quantius, Dominik A1 - Reershemius, Siebo A1 - Renger, Thomas A1 - Riemann, Johannes A1 - Rogez, Yves A1 - Ruffer, Michael A1 - Sasaki, Kaname A1 - Schmitz, Nicole A1 - Seboldt, Wolfgang A1 - Seefeldt, Patric A1 - Spietz, Peter A1 - Spröwitz, Tom A1 - Sznajder, Maciej A1 - Tóth, Norbert A1 - Vergaaij, Merel A1 - Viavattene, Giulia A1 - Wejmo, Elisabet A1 - Wiedemann, Carsten A1 - Wolff, Friederike A1 - Ziach, Christian T1 - Flights are ten a sail – Re-use and commonality in the design and system engineering of small spacecraft solar sail missions with modular hardware for responsive and adaptive exploration T2 - 70th International Astronautical Congress (IAC) KW - system engineering KW - small solar system body characterisation KW - small spacecraft solar sail KW - small spacecraft asteroid lander KW - responsive space Y1 - 2019 SN - 9781713814856 N1 - 70th International Astronautical Congress (IAC), Washington D.C., United States, 21-25 October 2019 SP - 1 EP - 7 ER - TY - CHAP A1 - Grundmann, Jan Thimo A1 - Bauer, Waldemar A1 - Boden, Ralf Christian A1 - Ceriotti, Matteo A1 - Cordero, Federico A1 - Dachwald, Bernd A1 - Dumont, Etienne A1 - Grimm, Christian D. A1 - Hercik, D. A1 - Herique, A. A1 - Ho, Tra-Mi A1 - Jahnke, Rico A1 - Kofman, Wlodek A1 - Lange, Caroline A1 - Lichtenheldt, Roy A1 - McInnes, Colin R. A1 - Mikschl, Tobias A1 - Mikulz, Eugen A1 - Montenegro, Sergio A1 - Moore, Iain A1 - Pelivan, Ivanka A1 - Peloni, Alessandro A1 - Plettemeier, Dirk A1 - Quantius, Dominik A1 - Reershemius, Siebo A1 - Renger, Thomas A1 - Riemann, Johannes A1 - Rogez, Yves A1 - Ruffer, Michael A1 - Sasaki, Kaname A1 - Schmitz, Nicole A1 - Seboldt, Wolfgang A1 - Seefeldt, Patric A1 - Spietz, Peter A1 - Spröwitz, Tom A1 - Sznajder, Maciej A1 - Toth, Norbert A1 - Viavattene, Giulia A1 - Wejmo, Elisabet A1 - Wolff, Friederike A1 - Ziach, Christian T1 - Responsive integrated small spacecraft solar sail and payload design concepts and missions T2 - Conference: 5th International Symposium on Solar Sailing (ISSS 2019) N2 - Asteroid mining has the potential to greatly reduce the cost of in-space manufacturing, production of propellant for space transportation and consumables for crewed spacecraft, compared to launching the required resources from Earth’s deep gravity well. This paper discusses the top-level mission architecture and trajectory design for these resource-return missions, comparing high-thrust trajectories with continuous low-thrust solar-sail trajectories. This work focuses on maximizing the economic Net Present Value, which takes the time-cost of finance into account and therefore balances the returned resource mass and mission duration. The different propulsion methods will then be compared in terms of maximum economic return, sets of attainable target asteroids, and mission flexibility. This paper provides one more step towards making commercial asteroid mining an economically viable reality by integrating trajectory design, propulsion technology and economic modelling. Y1 - 2019 N1 - Conference: 5th International Symposium on Solar Sailing (ISSS 2019)At: Aachen, Germany ER -