TY  - JOUR
A1  - Demmer, Julius K.
A1  - Chowdhury, Nilanjan Pal
A1  - Selmer, Thorsten
A1  - Ermler, Ulrich
A1  - Buckel, Wolfgang
T1  - The semiquinone swing in the bifurcating electron transferring flavoprotein/butyryl-CoA dehydrogenase complex from Clostridium difficile
JF  - Nature Communications
Y1  - 2017
U6  - https://doi.org/10.1038/s41467-017-01746-3
SN  - 2041-1723
N1  - Article number 1577
VL  - 8
IS  - 1
SP  - 1
EP  - 10
ER  - 
TY  - JOUR
A1  - Meliß, Michael
A1  - Späte, Frank
T1  - The solar heating system with seasonal storage at the Solar-Campus Jülich
JF  - Solar energy. Vol. 69 (2000), iss. 6
Y1  - 2000
SN  - 0038-092X
SP  - 525
EP  - 533
ER  - 
TY  - JOUR
A1  - Hennecke, Klaus
A1  - Schwarzbözl, Peter
A1  - Hoffschmidt, Bernhard
A1  - Göttsche, Joachim
A1  - Koll, G.
A1  - Beuter, M.
A1  - Hartz, T.
T1  - The solar power tower Jülich – a solar thermal power plant for test and demonstration of air receiver
JF  - Solar energy and human settlement : Elektronische Ressource : proceedings of ISES world congress 2007 ; (Vol. I - Vol. V) / [ISES Solar World Congress. ISES, International Solar Energy Society]. D. Yogi Goswami ; Yuwen Zhao
Y1  - 2007
SN  - 978-7-302-16146-2
N1  - Solar World Congress <2007, Beijing> ; International Solar Energy Society
SP  - 1749
EP  - 1753
PB  - Tsinghua Univ. Press
CY  - Beijing
ER  - 
TY  - CHAP
A1  - Koll, Gerrit
A1  - Schwarzbözl, Peter
A1  - Hennecke, Klaus
A1  - Hartz, Thomas
A1  - Schmitz, Mark
A1  - Hoffschmidt, Bernhard
T1  - The Solar Tower Jülich - a research and demonstration plant for central receiver systems
T2  - SolarPACES 2009 : electricity, fuels and clean water powered by the sun ; 15 - 18 September 2009, Berlin, Germany ; the 15th SolarPACES conference ; proceedings
Y1  - 2009
SN  - 9783000287558
PB  - Deutsches Zentrum f. Luft- u. Raumfahrt
CY  - Stuttgart
ER  - 
TY  - CHAP
A1  - Schwarzbözl, Peter
A1  - Pomp, Stefan
A1  - Koll, Gerrit
A1  - Hennecke, Klaus
A1  - Hartz, Thomas
A1  - Schmitz, Mark
A1  - Hoffschmidt, Bernhard
T1  - The solar tower Jülich - first operational experiences and test results
T2  - SolarPACES 2010 : the CSP Conference: electricity, fuels and clean water from concentrated solar energy ; 21 to 24 September 2010, Perpignan, France
Y1  - 2010
SP  - 8
EP  - 9
PB  - Soc. OSC
CY  - Saint Maur
ER  - 
TY  - CHAP
A1  - Meliß, Michael
A1  - Späte, Frank
A1  - Lange, Harald
T1  - The Solar-Campus Jülich - an interdisciplinary project
T2  - Building a new century. 5th Conference on Solar Architecture and Design, Bonn, 27th of May 1998. Ed. by Eurosolar e.V. Ed. by Irm Pontenagel.
Y1  - 1999
SN  - 3-933745-03-9
SP  - 382
EP  - 387
PB  - Eurosolar-Verl.
CY  - Bonn
ER  - 
TY  - JOUR
A1  - Schäfer, Horst
A1  - Lampey, H.
T1  - The stray-field structure of a HI-B sheet in the vicinity of laser scratches
JF  - Journal of Magnetism and Magnetic Materials. 75 (1988), H. 3
Y1  - 1988
SN  - 0304-8853
SP  - 339
EP  - 344
ER  - 
TY  - JOUR
A1  - Dikta, Gerhard
T1  - The Strong Law under Semiparametric Random Censorship Models
JF  - Journal of Statistical Planning and Inference. 83 (2000), H. 1
Y1  - 2000
SN  - 0378-3758
SP  - 1
EP  - 10
ER  - 
TY  - JOUR
A1  - Stulpe, Werner
A1  - Busch, Paul
T1  - The structure of classical extensions of quantum probability theory
JF  - Journal of Mathematical Physics. 49 (2008), H. 3
Y1  - 2008
SN  - 1089-7658
N1  - 032104
SP  - 1
EP  - 22
ER  - 
TY  - JOUR
A1  - Baumann, Marcus
A1  - Lancelot, C.
A1  - Brandini, F.
A1  - Sakshaug, E.
T1  - The taxonomic identity of the cosmopolitan prymnesiophyte Phaeocystis, a morphological and ecophysiological approach / Baumann, M.E.M. ; Lancelot, C. ; Brandini, F. ; Sakshaug, E. ; John M.
JF  - Journal of Marine Systems. 5 (1994), H. 1
Y1  - 1994
SN  - 0924-7963
SP  - 5
EP  - 22
ER  - 
TY  - JOUR
A1  - Jacobs, Stephan
T1  - The Teamwork Approach in Requirements Engineering
JF  - The nature of requirements engineering / Matthias Jarke ... (Hrsg.)
Y1  - 1999
SN  - 3-8265-6174-0
PB  - Shaker
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Bode, Jürgen
A1  - Schlake, Thomas
A1  - Iber, Michaela
A1  - Schübeler, Dirk
A1  - Seibler, Jost
A1  - Snezhkov, Evgeney
A1  - Nikolaev, Lev
T1  - The transgeneticist's toolbox: novel methods for the targeted modification of eukaryotic genomes
JF  - Biological Chemistry
Y1  - 2000
U6  - https://doi.org/10.1515/BC.2000.103
SN  - 1431-6730
VL  - 381
IS  - 9-10
SP  - 801
EP  - 813
ER  - 
TY  - JOUR
A1  - Digel, Ilya
A1  - Zhubanova, Azhar A.
A1  - Nojima, H.
A1  - Artmann, Gerhard
T1  - The use of bactericidal effects of cluster ions generated by plasma in medical biotechnology
JF  - Biotechnologija : teorija i praktika (2004)
Y1  - 2004
SN  - 1028-9399
SP  - 46
EP  - 52
ER  - 
TY  - CHAP
A1  - Azat, Seitkhan
A1  - Kerimkulova, Almagul R.
A1  - Mansurov, Zulkhair A.
A1  - Adekenov, Sergazy
A1  - Artmann, Gerhard
T1  - The Use of Fusicoccin as Anticancer Compound
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - The problem of creation and use of sorption materials is of current interest for the practice of the modern medicine and agriculture. Practical importance is production of a biostimulant using a carbon sorbent for a significant increase in productivity, which is very relevant for the regions of Kazakhstan. It is known that a plant phytohormone—fusicoccin—in nanogram concentrations transforms cancer cells to the state of apoptosis. In this regard, there is a scientific practical interest in the development of a highly efficient method for producing fusicoccin from extract of germinated wheat seeds. According to the results of computer modeling, cleaning composite components of fusicoccin using microporous carbon adsorbents not suitable as the size of the molecule of fusicoccin more than micropores and the optimum pore size for purification of constituents of fusicoccin was determined by computer simulation.
Y1  - 2020
SN  - 978-0-429-42864-7
U6  - https://doi.org/10.1201/9780429428647-8
SP  - 149
EP  - 172
PB  - Jenny Stanford Publishing
CY  - New York
ER  - 
TY  - JOUR
A1  - Wolf, Martin R.
A1  - Schlick, Christopher
A1  - Springer, J.
ED  - Miyamoto, Hiroyuki
T1  - The use of implicit communication mechanisms in desktop-teleconferencing-systems
JF  - Proceedings of WWDU '97 Tokyo, Fifth International Scientific Conference on Work with Display Units : November 3 - 5, 1997, Tokyo
Y1  - 1997
N1  - International Scientific Conference on Work with Display Units ; International Scientific Conference on Work with Display Units ; (5 ; 1997.11.03-05 ; Tokyo)
SP  - 193
EP  - 194
PB  - -
CY  - Tokyo
ER  - 
TY  - JOUR
A1  - Schöning, Michael Josef
A1  - Schroth, P.
A1  - Schütz, S.
T1  - The use of insect chemoreceptors for the assembly of biosensors based on semiconductor field-effect sensors
JF  - Electroanalysis. 12 (2000), H. 9
Y1  - 2000
SN  - 1040-0397
SP  - 645
EP  - 652
ER  - 
TY  - JOUR
A1  - Ciobanu, Octavian
A1  - Staat, Manfred
A1  - Rahimi, Alireza
T1  - The use of open source software in biomechanical finite element analysis
JF  - Buletinul Institutului Politehnic din Iaşi / Universitatea Tehnică Gh. Asachi, Iaşi Secţia 5, Construcţii de maşini = Machine construction = Bulletin of the Polytechnic Institute of Jassy = Izvestija Jasskogo Politechničeskogo Instituta
Y1  - 2008
SN  - 1011-2855
VL  - 54
IS  - 7/8
SP  - 213
EP  - 220
ER  - 
TY  - JOUR
A1  - Bernau, C. R.
A1  - Knödler, Matthias
A1  - Emonts, Jessica
A1  - Jäpel, Ronald Colin
A1  - Buyel, Johannes Felix
T1  - The use of predictive models to develop chromatography-based purification processes
JF  - Frontiers in Bioengineering and Biotechnology
N2  - Chromatography is the workhorse of biopharmaceutical downstream processing because it can selectively enrich a target product while removing impurities from complex feed streams. This is achieved by exploiting differences in molecular properties, such as size, charge and hydrophobicity (alone or in different combinations). Accordingly, many parameters must be tested during process development in order to maximize product purity and recovery, including resin and ligand types, conductivity, pH, gradient profiles, and the sequence of separation operations. The number of possible experimental conditions quickly becomes unmanageable. Although the range of suitable conditions can be narrowed based on experience, the time and cost of the work remain high even when using high-throughput laboratory automation. In contrast, chromatography modeling using inexpensive, parallelized computer hardware can provide expert knowledge, predicting conditions that achieve high purity and efficient recovery. The prediction of suitable conditions in silico reduces the number of empirical tests required and provides in-depth process understanding, which is recommended by regulatory authorities. In this article, we discuss the benefits and specific challenges of chromatography modeling. We describe the experimental characterization of chromatography devices and settings prior to modeling, such as the determination of column porosity. We also consider the challenges that must be overcome when models are set up and calibrated, including the cross-validation and verification of data-driven and hybrid (combined data-driven and mechanistic) models. This review will therefore support researchers intending to establish a chromatography modeling workflow in their laboratory.
KW  - biopharmaceutical production process
KW  - Data-driven models
KW  - downstream processing design
KW  - experiment quality
KW  - hybrid model validation
Y1  - 2022
U6  - https://doi.org/10.3389/fbioe.2022.1009102
SN  - 2296-4185 (online-ressource)
IS  - 10
PB  - Frontiers Media
CY  - Lausanne
ER  - 
TY  - CHAP
A1  - Henderson, Colin J.
A1  - Wolf, C. Roland
A1  - Scheer, Nico
ED  - Woolf, Thomas F.
T1  - The use of transgenic animals to study drug metabolism
T2  - Handbook of Drug Metabolism. 2nd Edition
Y1  - 2009
SN  - 978-1-4200-7647-9
SP  - 637
EP  - 658
PB  - Informa Healthcare
CY  - New York
ER  - 
TY  - JOUR
A1  - Wittmann, Klaus
A1  - Padeken, D.
T1  - The User Center for Microgravity MUSC - Support for space experiments
JF  - DLR-Nachrichten. 70 (1993)
Y1  - 1993
SN  - 0937-0420
SP  - 19
EP  - 24
ER  -