TY  - JOUR
A1  - Neumaier, Felix
A1  - Kotliar, Konstantin
A1  - Haeren, Roel Hubert Louis
A1  - Temel, Yasin
A1  - Lüke, Jan Niklas
A1  - Seyam, Osama
A1  - Lindauer, Ute
A1  - Clusmann, Hans
A1  - Hescheler, Jürgen
A1  - Schubert, Gerrit Alexander
A1  - Schneider, Toni
A1  - Albanna, Walid
T1  - Retinal Vessel Responses to Flicker Stimulation Are Impaired in Ca v 2.3-Deficient Mice—An in- vivo Evaluation Using Retinal Vessel Analysis (RVA)
JF  - Frontiers in Neurology
Y1  - 2021
U6  - https://doi.org/10.3389/fneur.2021.659890
VL  - 12
SP  - 1
EP  - 11
PB  - Frontiers
ER  - 
TY  - CHAP
A1  - Haugg, Albert Thomas
A1  - Kreyer, Jörg
A1  - Kemper, Hans
A1  - Hatesuer, Katerina
A1  - Esch, Thomas
T1  - Heat exchanger for ORC. adaptability and optimisation potentials
T2  - IIR International Rankine 2020 Conference
N2  - The recovery of waste heat requires heat exchangers to extract it from a liquid or gaseous medium into another working medium, a refrigerant. In Organic Rankine Cycles (ORC) on Combustion Engines there are two major heat sources, the exhaust gas and the water/glycol fluid from the engine’s cooling circuit. A heat exchanger design must be adapted to the different requirements and conditions resulting from the heat sources, fluids, system configurations, geometric restrictions, and etcetera. The Stacked Shell Cooler (SSC) is a new and very specific design of a plate heat exchanger, created by AKG, which allows with a maximum degree of freedom the optimization of heat exchange rate and the reduction of the related pressure drop. This optimization in heat exchanger design for ORC systems is even more important, because it reduces the energy consumption of the system and therefore maximizes the increase in overall efficiency of the engine.
Y1  - 2020
U6  - https://doi.org/10.18462/iir.rankine.2020.1224
N1  - IIR International Rankine 2020 Conference - Heating, Cooling, Power Generation. Glasgow, 2020.
ER  - 
TY  - CHAP
A1  - Atmane, Ilias
A1  - Hirech, Kamal
A1  - Kassmi, K.
A1  - Mahdi, Zahra
A1  - Alexopoulos, Spiros
A1  - Schwarzer, Klemens
A1  - Chayeb, H.
A1  - Bachiri, N.
ED  - Omrane, Amina
ED  - Kassmi, Khalil
ED  - Akram, Muhammad Wasim
ED  - Khanna, Ashish
ED  - Mostafiz, Imtiaz
T1  - Design and realization of a pilot solar desalination plant in Douar El Hamri in the province of Berkane (Morocco)
T2  - Sustainable entrepreneurship, renewable energy-based projects, and digitalization
N2  - Producing fresh water from saline water has become one of the most difficult challenges to overcome especially with the high demand and shortage of fresh water. In this context, as part of a collaboration with Germany, the authors propose a design and implementation of a pilot multi-stage solar desalination system (MSD), remotely controlled, at Douar Al Hamri in the rural town of Boughriba in the province of Berkane, Morocco. More specifically, they present their contribution on the remote control and supervision system, which makes the functioning of the MSD system reliable and guarantees the production of drinking water for the population of Douar. The results obtained show that the electronic cards and computer communication software implemented allow the acquisition of all electrical (currents, voltages, powers, yields), thermal (temperatures of each stage), and meteorological (irradiance and ambient temperature), remote control and maintenance (switching on, off, data transfer). By comparing with the literature carried out in the field of solar energy, the authors conclude that the MSD and electronic desalination systems realized during this work represent a contribution in terms of the reliability and durability of providing drinking water in rural and urban areas.
Y1  - 2020
SN  - 9781000292541 (E-Book)
SN  - 9781003097921 (E-Book)
SN  - 9780367468378 (Hardcover)
PB  - CRC Press
CY  - Boca Raton, Fa.
ER  - 
TY  - CHAP
A1  - Alexopoulos, Spiros
A1  - Breitbach, Gerd
A1  - Hoffschmidt, Bernhard
T1  - Optimization of the channel form geometry of porous ReSiC ceramic membrane modules
T2  - Proceedings / International Conference & Exhibition for Filtration and Separation Technology, FILTECH 2009 : October 13 - 15, 2009, Wiesbaden, Germany. Vol. 2
Y1  - 2009
SN  - 978-3-941655-36-2
SP  - 686
EP  - 693
PB  - Filtech Exhibitions Germany
CY  - Meerbusch
ER  - 
TY  - JOUR
A1  - Degering, Christian
A1  - Eggert, Thorsten
A1  - Puls, Michael
A1  - Bongaerts, Johannes
A1  - Evers, Stefan
A1  - Maurer, Karl-Heinz
A1  - Jaeger, Karl-Erich
T1  - Optimization of protease secretion in Bacillus subtilis and Bacillus licheniformis by screening of homologous and herologous signal peptides
JF  - Applied and environmental microbiology
N2  - Bacillus subtilis and Bacillus licheniformis are widely used for the large-scale industrial production of proteins. These strains can efficiently secrete proteins into the culture medium using the general secretion (Sec) pathway. A characteristic feature of all secreted proteins is their N-terminal signal peptides, which are recognized by the secretion machinery. Here, we have studied the production of an industrially important secreted protease, namely, subtilisin BPN′ from Bacillus amyloliquefaciens. One hundred seventy-three signal peptides originating from B. subtilis and 220 signal peptides from the B. licheniformis type strain were fused to this secretion target and expressed in B. subtilis, and the resulting library was analyzed by high-throughput screening for extracellular proteolytic activity. We have identified a number of signal peptides originating from both organisms which produced significantly increased yield of the secreted protease. Interestingly, we observed that levels of extracellular protease were improved not only in B. subtilis, which was used as the screening host, but also in two different B. licheniformis strains. To date, it is impossible to predict which signal peptide will result in better secretion and thus an improved yield of a given extracellular target protein. Our data show that screening a library consisting of homologous and heterologous signal peptides fused to a target protein can identify more-effective signal peptides, resulting in improved protein export not only in the original screening host but also in different production strains.
Y1  - 2010
U6  - https://doi.org/10.1128/AEM.01146-10
SN  - 1098-5336 (E-Journal); 0003-6919 (Print); 0099-2240 (Print)
VL  - 76
IS  - 19
SP  - 6370
EP  - 6378
PB  - American Society for Microbiology
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Deppe, Veronika Maria
A1  - Bongaerts, Johannes
A1  - O'Connell, Timothy
A1  - Maurer, Karl-Heinz
A1  - Meinhardt, Friedhelm
T1  - Enzymatic deglycation of Amadori products in bacteria
JF  - Applied microbiology and biotechnology
Y1  - 2011
SN  - 1432-0614 (E-Journal); 0171-1741 (Print); 0175-7598 (Print); 0340-2118 (Print)
VL  - Vol. 90
IS  - Iss. 2
SP  - 399
EP  - 406
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Ille, Fabian
A1  - Schramm, S.
A1  - Adam, M.
A1  - Backes, K.
A1  - Anthrakidis, Anette
A1  - Faber, Christian
T1  - Kraft-Wärme-Kälte-Kopplung im Leistungsbereich in 10kW mit periodisch arbeitender Sorptionsmaschine
T2  - DKV-Tagungsbericht. 35,2,1. Deutsche Kälte-Klima-Tagung 2008 Ulm
Y1  - 2009
SN  - 978-3-932715-44-0
SP  - 305
EP  - 320
PB  - Dt. Kälte- und Klimatechnischer Verein
CY  - Hannover
ER  - 
TY  - CHAP
A1  - Ahlbrink, Nils
A1  - Alexopoulos, Spiros
A1  - Andersson, Joel A. E.
A1  - Belhomme, B.
A1  - Teixeira Boura, Cristiano José
A1  - Gall, Jan
A1  - Hirsch, Tobias
T1  - viCERP - the Virtual Institute of Central Receiver Power Plant
T2  - MATHMOD 2009 - 6th Vienna International Conference on Mathematical Modelling : February 11 - 13, 2009, Vienna, Austria. ARGESIM Report. No. 35
Y1  - 2009
SN  - 978-3-901608-35-3
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Alexopoulos, Spiros
A1  - Hoffschmidt, Bernhard
T1  - Advances in solar tower technology
JF  - Wiley interdisciplinary reviews : Energy and Environment : WIREs
Y1  - 2017
U6  - https://doi.org/10.1002/wene.217
SN  - 2041-840X
VL  - 6
IS  - 1
SP  - 1
EP  - 19
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Funke, Harald
A1  - Beckmann, Nils
A1  - Keinz, Jan
A1  - Abanteriba, Sylvester
T1  - Comparison of Numerical Combustion Models for Hydrogen and Hydrogen-Rich Syngas Applied for Dry-Low-Nox-Micromix-Combustion
JF  - Journal of Engineering for Gas Turbines and Power
N2  - The Dry-Low-NOx (DLN) Micromix combustion technology has been developed as low emission combustion principle for industrial gas turbines fueled with hydrogen or syngas. The combustion process is based on the phenomenon of jet-in-crossflow-mixing (JICF). Fuel is injected perpendicular into the air-cross-flow and burned in a multitude of miniaturized, diffusion-like flames. The miniaturization of the flames leads to a significant reduction of NOx emissions due to the very short residence time of reactants in the flame. In the Micromix research approach, computational fluid dynamics (CFD) analyses are validated toward experimental results. The combination of numerical and experimental methods allows an efficient design and optimization of DLN Micromix combustors concerning combustion stability and low NOx emissions. The paper presents a comparison of several numerical combustion models for hydrogen and hydrogen-rich syngas. They differ in the complexity of the underlying reaction mechanism and the associated computational effort. The performance of a hybrid eddy-break-up (EBU) model with a one-step global reaction is compared to a complex chemistry model and a flamelet generated manifolds (FGM) model, both using detailed reaction schemes for hydrogen or syngas combustion. Validation of numerical results is based on exhaust gas compositions available from experimental investigation on DLN Micromix combustors. The conducted evaluation confirms that the applied detailed combustion mechanisms are able to predict the general physics of the DLN-Micromix combustion process accurately. The FGM method proved to be generally suitable to reduce the computational effort while maintaining the accuracy of detailed chemistry.
Y1  - 2018
U6  - https://doi.org/10.1115/1.4038882
SN  - 0742-4795
N1  - Article number 081504;
Paper No: GTP-17-1567
VL  - 140
IS  - 8
PB  - ASME
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Götten, Falk
A1  - Havermann, Marc
A1  - Braun, Carsten
A1  - Marino, Matthew
A1  - Bil, Cees
T1  - Improved Form Factor for Drag Estimation of Fuselages with Various Cross Sections
JF  - Journal of Aircraft
N2  - The paper presents an aerodynamic investigation of 70 different streamlined bodies with fineness ratios ranging from 2 to 10. The bodies are chosen to idealize both unmanned and small manned aircraft fuselages and feature cross-sectional shapes that vary from circular to quadratic. The study focuses on friction and pressure drag in dependency of the individual body’s fineness ratio and cross section. The drag forces are normalized with the respective body’s wetted area to comply with an empirical drag estimation procedure. Although the friction drag coefficient then stays rather constant for all bodies, their pressure drag coefficients decrease with an increase in fineness ratio. Referring the pressure drag coefficient to the bodies’ cross-sectional areas shows a distinct pressure drag minimum at a fineness ratio of about three. The pressure drag of bodies with a quadratic cross section is generally higher than for bodies of revolution. The results are used to derive an improved form factor that can be employed in a classic empirical drag estimation method. The improved formulation takes both the fineness ratio and cross-sectional shape into account. It shows superior accuracy in estimating streamlined body drag when compared with experimental data and other form factor formulations of the literature.
Y1  - 2020
U6  - https://doi.org/10.2514/1.C036032
SN  - 1533-3868
SP  - 1
EP  - 13
PB  - AIAA
CY  - Reston, Va.
ER  - 
TY  - JOUR
A1  - Ille, F.
A1  - Schramm, S.
A1  - Adam, M.
A1  - Backes, K.
A1  - Faber, Christian
A1  - Anthrakidis, Anette
T1  - Kraft-Wärme-Kälte-Kopplung im Leistungsbereich von 10 kW mit periodisch arbeitender Sorptionsmaschine
JF  - VDI-Tage der Gebäudetechnik 2008 : Tagung Dortmund, 28. und 29. Mai 2008 / VDI-Gesellschaft Technische Gebäudeausrüstung
Y1  - 2008
SN  - 978-3-18-092043-6
N1  - VDI-Berichte ; 2043 ; 2. VDI-Tage der Gebäudetechnik 2008, VDI-Gesellschaft Technische Gebäudeausrüstung (VDI-TGA), Dortmund, DE, 28.-29. Mai, 2008
SP  - 103
EP  - 116
PB  - VDI-Verl.
CY  - Düsseldorf
ER  - 
TY  - JOUR
A1  - Muschallik, Lukas
A1  - Molinnus, Denise
A1  - Bongaerts, Johannes
A1  - Pohl, Martina
A1  - Wagner, Torsten
A1  - Schöning, Michael Josef
A1  - Siegert, Petra
A1  - Selmer, Thorsten
T1  - (R,R)-Butane-2,3-diol Dehydrogenase from Bacillus clausii DSM 8716T: Cloning and Expression of the bdhA-Gene, and Initial Characterization of Enzyme
JF  - Journal of Biotechnology
N2  - The gene encoding a putative (R,R)-butane-2,3-diol dehydrogenase (bdhA) from Bacillus clausii DSM 8716T was isolated, sequenced and expressed in Escherichia coli. The amino acid sequence of the encoded protein is only distantly related to previously studied enzymes (identity 33–43%) and exhibited some uncharted peculiarities. An N-terminally StrepII-tagged enzyme variant was purified and initially characterized. The isolated enzyme catalyzed the (R)-specific oxidation of (R,R)- and meso-butane-2,3-diol to (R)- and (S)-acetoin with specific activities of 12 U/mg and 23 U/mg, respectively. Likewise, racemic acetoin was reduced with a specific activity of up to 115 U/mg yielding a mixture of (R,R)- and meso-butane-2,3-diol, while the enzyme reduced butane-2,3-dione (Vmax 74 U/mg) solely to (R,R)-butane-2,3-diol via (R)-acetoin. For these reactions only activity with the co-substrates NADH/NAD+ was observed. The enzyme accepted a selection of vicinal diketones, α-hydroxy ketones and vicinal diols as alternative substrates. Although the physiological function of the enzyme in B. clausii remains elusive, the data presented herein clearly demonstrates that the encoded enzyme is a genuine (R,R)-butane-2,3-diol dehydrogenase with potential for applications in biocatalysis and sensor development.
Y1  - 2017
U6  - https://doi.org/10.1016/j.jbiotec.2017.07.020
SN  - 0168-1656
VL  - 258
SP  - 41
EP  - 50
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Reger, Vitali
A1  - Kuhnhenne, Markus
A1  - Ebbert, Thiemo
A1  - Hachul, Helmut
A1  - Blanke, Tobias
A1  - Döring, Bernd
T1  - Nutzung erneuerbarer Energien durch thermische Aktivierung von Komponenten aus Stahl
JF  - Stahlbau
N2  - Die Versorgung von Neubauten soll möglichst weitgehend unabhängig von fossilen Energieträgern erfolgen. Erneuerbare Energien spielen dafür eine gewichtige Rolle. Eine gute Möglichkeit, erneuerbare Energien ohne viel zusätzlichen Aufwand nutzbar zu machen, ist, bereits vorhandenen Komponenten im Gebäude zusätzliche Funktionen zu geben. Hier kann bspw. die Fassade oder das Dach solarthermisch aktiviert oder durch Fotovoltaikmodule ergänzt werden. Auch Tiefgründungen können neben der statischen Funktion noch eine geothermische Funktion zur Aufnahme oder Abgabe von Wärme erhalten. Neben der Erzeugung bietet sich auch für die Verteilung der Wärme oder Kälte im Gebäude die Integration in Bauteile an. Hier kann bspw. der Boden durch eine Fußbodenheizung oder die Decke durch Deckenstrahlplatten aktiviert werden.

Im Rahmen der Veröffentlichung wird auf die thermische Aktivierung von Stahlkomponenten eingegangen. Es wird eine Lösung vorgestellt, die vorgehängte hinterlüftete Stahlfassade (VHF) solarthermisch zu aktivieren. Außerdem werden zwei Möglichkeiten zur geothermischen Aktivierung von Tiefgründungen mittels Stahlpfählen gezeigt. Zuletzt wird ein System zur thermischen Aktivierung von Stahltrapezprofilen an der Decke erläutert, welches Wärme zuführen oder bei Bedarf abführen kann.
Y1  - 2020
U6  - https://doi.org/10.1002/stab.202000031
SN  - 1437-1049
VL  - 2020
IS  - Volume 89, Issue 6512-519
SP  - 512
EP  - 519
PB  - Ernst & Sohn
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Reimer, Lars
A1  - Braun, Carsten
A1  - Ballmann, Josef
T1  - Computational study of the aeroelastic equilibrium configuration of a swept wind tunnel wing model in subsonic flow
T2  - High performance computing in science and engineering '06. Transactions of the High Performance Computing Center Stuttgart (HLRS) 2006 /  Wolfgang E. Nagel ... Eds.
N2  - In the Collaborative Research Center SFB 401 at RWTH Aachen University, the numerical aeroelastic method SOFIA for direct numerical aeroelastic simulation is being progressively developed. Numerical results obtained by applying SOFIA were compared with measured data of static and dynamic aeroelastic wind tunnel tests for an elastic swept wing in subsonic flow.
Y1  - 2007
SN  - 978-3-540-36165-7
SP  - 421
EP  - 434
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Jossek, Ralf
A1  - Bongaerts, Johannes
A1  - Sprenger, Georg A.
T1  - Characterization of a new feedback-resistant 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase AroF of Escherichia coli
JF  - FEMS microbiology letters
Y1  - 2001
SN  - 1574-6968
VL  - Vol. 202
IS  - Iss. 1
SP  - 145
EP  - 148
ER  - 
TY  - JOUR
A1  - Geier, Christian
A1  - Lehnertz, Klaus
A1  - Bialonski, Stephan
T1  - Time-dependent degree-degree correlations in epileptic brain networks: from assortative to dissortative mixing
JF  - Frontiers in Human Neuroscience
Y1  - 2015
U6  - https://doi.org/10.3389/fnhum.2015.00462
SN  - 1662-5161
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  - 
TY  - JOUR
A1  - Wilming, Anja
A1  - Begemann, Jens
A1  - Kuhne, Stefan
A1  - Regestein, Lars
A1  - Bongaerts, Johannes
A1  - Evers, Stefan
A1  - Maurer, Karl-Heinz
A1  - Büchs, Jochen
T1  - Metabolic studies of γ-polyglutamic acid production in Bacillus licheniformis by small-scale continuous cultivations
JF  - Biochemical engineering journal
Y1  - 2013
SN  - 1873-295X (E-Journal); 1369-703X (Print)
VL  - Vol. 73
SP  - 29
EP  - 37
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Alexopoulos, Spiros
T1  - Simulation model for the transient process behaviour of solar aluminium recycling in a rotary kiln
JF  - Applied Thermal Engineering
Y1  - 2015
U6  - https://doi.org/10.1016/j.applthermaleng.2015.01.007
SN  - 1359-4311
N1  - Autor im Original: Spiridon O. Alexopoulos
VL  - 78
SP  - 387
EP  - 396
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Funke, Harald
A1  - Beckmann, Nils
A1  - Keinz, Jan
A1  - Abanteriba, Sylvester
T1  - Numerical and Experimental Evaluation of a Dual-Fuel Dry-Low-NOx Micromix Combustor for Industrial Gas Turbine Applications
T2  - Proceedings of the ASME Turbo Expo 2017: Turbomachinery Technical Conference and Exposition. Volume 4B: Combustion, Fuels and Emissions. Charlotte, North Carolina, USA. June 26–30, 2017
N2  - The Dry-Low-NOx (DLN) Micromix combustion technology has been developed originally as a low emission alternative for industrial gas turbine combustors fueled with hydrogen. Currently the ongoing research process targets flexible fuel operation with hydrogen and syngas fuel.

The non-premixed combustion process features jet-in-crossflow-mixing of fuel and oxidizer and combustion through multiple miniaturized flames. The miniaturization of the flames leads to a significant reduction of NOx emissions due to the very short residence time of reactants in the flame.

The paper presents the results of a numerical and experimental combustor test campaign. It is conducted as part of an integration study for a dual-fuel (H2 and H2/CO 90/10 Vol.%) Micromix combustion chamber prototype for application under full scale, pressurized gas turbine conditions in the auxiliary power unit Honeywell Garrett GTCP 36-300.

In the presented experimental studies, the integration-optimized dual-fuel Micromix combustor geometry is tested at atmospheric pressure over a range of gas turbine operating conditions with hydrogen and syngas fuel. The experimental investigations are supported by numerical combustion and flow simulations. For validation, the results of experimental exhaust gas analyses are applied.

Despite the significantly differing fuel characteristics between pure hydrogen and hydrogen-rich syngas the evaluated dual-fuel Micromix prototype shows a significant low NOx performance and high combustion efficiency. The combustor features an increased energy density that benefits manufacturing complexity and costs.
Y1  - 2017
SN  - 978-0-7918-5085-5
U6  - https://doi.org/10.1115/GT2017-64795
N1  - Paper No. GT2017-64795, V04BT04A045
PB  - ASME
CY  - New York
ER  -