TY  - JOUR
A1  - Boecker, Henning
A1  - Kuwert, Torsten
A1  - Langen, Karl-J.
A1  - Lange, Herwig W.
A1  - Czech, Norbert
A1  - Ziemons, Karl
A1  - Herzog, Hans
A1  - Shikare, Shekar
A1  - Weindl, Anton
A1  - Feinendegen, Ludwig E.
T1  - SPECT with HMPAO compared to PET with FDG in Huntington disease
JF  - Journal of Computer Assisted Tomography
Y1  - 1994
SN  - 1532-3145
VL  - 18
IS  - 4
SP  - 542
EP  - 548
ER  - 
TY  - JOUR
A1  - Langen, Karl J.
A1  - Ziemons, Karl
A1  - Kiwit, Jürgen C. W.
A1  - Herzog, Hans
A1  - Kuwert, Torsten
A1  - Bock, Wolfgang
A1  - Stöcklin, Gerhard
A1  - Feinendegen, Ludwig E.
A1  - Müller-Gärtner, Hans-W.
T1  - 3-[123I]iodo-α-methyltyrosine and [methyl-11C]-L-methionine uptake in cerebral gliomas: a compara-tive study using SPECT and PET
JF  - Journal of Nuclear Medicine
Y1  - 1997
SN  - 0161-5505
VL  - 38
IS  - 4
SP  - 517
EP  - 522
ER  - 
TY  - JOUR
A1  - Schmidt, Daniela
A1  - Langen, Karl-J.
A1  - Herzog, Hans
A1  - Wirths, Jochen
A1  - Holschbach, Markus
A1  - Kiwit, Jürgen C. W.
A1  - Ziemons, Karl
A1  - Coenen, Heinz-H.
A1  - Müller-Gärtner, Hans-W.
T1  - Whole-body kinetics and dosimetry of L-3[123I]-iodo-α-methyltyrosine
JF  - European Journal of Nuclear Medicine
Y1  - 1997
SN  - 1619-7089
VL  - 24
IS  - 9
SP  - 1162
EP  - 1166
ER  - 
TY  - CHAP
A1  - Müller-Veggian, Mattea
A1  - Kops, Elena Rota
A1  - Quin, Peng
A1  - Herzog, Hans
T1  - MRI Based Attenuation Correction for Brain PET Images
T2  - Advances in medical engineering / [3rd RPT - Remagener Physiktage together with the Second Scientific Workshop of Medical Robotics, Navigation and Visualization ... Remagen ... 7.-9. März 2007]. Thorsten M. Buzug (ed.) Part 1.
N2  - This work describes a procedure to yield attenuation maps from MR images which are used for the absorption correction (AC) of brain PET data. Such an approach could be mandatory for future combined PET and MRI scanners, which probably do not include a transmission facility. T1-weighted MR images were segmented into brain tissue, bone, soft tissue, and sinus; attenuation coefficients corresponding to elemental composition and density as well as to 511 keV photon energy were respectively assigned. Attenuation maps containing up to four compartments were created and forward projected into sinograms with attenuation factors which then were used for AC during reconstruction of FDG-PET data. The commonly used AC based on a radioactive (68Ge) transmission scan served as reference. The reconstructed radioactivity values obtained with the MRI-based AC were about 20% lower than those obtained with PET-based AC if the skull was not taken into account. Considering the skull the difference was still about 10%. Our investigations demonstrate the feasibility of a MRI-based AC, but revealed also the necessity of a satisfying delineation of bone thickness which tends to be underestimated in our first approach of T1-weighted MR image segmentation.
Y1  - 2007
SN  - 978-3-540-68763-4
U6  - http://dx.doi.org/10.1007/978-3-540-68764-1_15
N1  - Springer proceedings in physics ; 114
SP  - 93
EP  - 97
PB  - Springer
CY  - Berlin
ER  - 
TY  - JOUR
A1  - Herzog, Hans
A1  - Pietrzyk, Uwe
A1  - Shah, N. Jon
A1  - Ziemons, Karl
T1  - The current state, challenges and perspectives of MR-PET
JF  - Neuroimage
N2  - Following the success of PET/CT during the last decade and the recent increasing proliferation of SPECT/CT, another hybrid imaging instrument has been gaining more and more interest: MR-PET. First combined, simultaneous PET and MR studies carried out in small animals demonstrated the feasibility of the new approach. Concurrently, some prototypes of an MR-PET scanner for simultaneous human brain studies have been built, their performance is being tested and preliminary applications have already been shown. Through this pioneering work, it has become clear that advances in the detector design are necessary for further optimization.

Recently, the different issues related to the present state and future prospects of MR-PET were presented and discussed during an international 2-day workshop at the Forschungszentrum Jülich, Germany, held after, and in conjunction with, the 2008 IEEE Nuclear Science Symposium and Medical Imaging Conference in Dresden, Germany on October 27–28, 2008. The topics ranged from small animal MR-PET imaging to human MR-BrainPET imaging, new detector developments, challenges/opportunities for ultra-high field MR-PET imaging and considerations of possible future research and clinical applications. This report presents a critical summary of the contributions made to the workshop.
Y1  - 2010
U6  - http://dx.doi.org/10.1016/j.neuroimage.2009.10.036
SN  - 1053-8119
VL  - 49
IS  - 3
SP  - 2072
EP  - 2082
PB  - Elsevier
CY  - Amsterdam
ER  -