TY  - CHAP
A1  - Müller-Veggian, Mattea
A1  - Kops, Elena Rota
A1  - Quin, Peng
A1  - Herzog, Hans
T1  - MRI Based Attenuation Correction for Brain PET Images
T2  - Advances in medical engineering / [3rd RPT - Remagener Physiktage together with the Second Scientific Workshop of Medical Robotics, Navigation and Visualization ... Remagen ... 7.-9. März 2007]. Thorsten M. Buzug (ed.) Part 1.
N2  - This work describes a procedure to yield attenuation maps from MR images which are used for the absorption correction (AC) of brain PET data. Such an approach could be mandatory for future combined PET and MRI scanners, which probably do not include a transmission facility. T1-weighted MR images were segmented into brain tissue, bone, soft tissue, and sinus; attenuation coefficients corresponding to elemental composition and density as well as to 511 keV photon energy were respectively assigned. Attenuation maps containing up to four compartments were created and forward projected into sinograms with attenuation factors which then were used for AC during reconstruction of FDG-PET data. The commonly used AC based on a radioactive (68Ge) transmission scan served as reference. The reconstructed radioactivity values obtained with the MRI-based AC were about 20% lower than those obtained with PET-based AC if the skull was not taken into account. Considering the skull the difference was still about 10%. Our investigations demonstrate the feasibility of a MRI-based AC, but revealed also the necessity of a satisfying delineation of bone thickness which tends to be underestimated in our first approach of T1-weighted MR image segmentation.
Y1  - 2007
SN  - 978-3-540-68763-4
U6  - https://doi.org/10.1007/978-3-540-68764-1_15
N1  - Springer proceedings in physics ; 114
SP  - 93
EP  - 97
PB  - Springer
CY  - Berlin
ER  - 
TY  - CHAP
A1  - Weber, Hans-Joachim
T1  - Applied physics of compressible and incompressible fluids
T2  - Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo
Y1  - 1998
SN  - 978-94-010-6306-7
SP  - 63
EP  - 84
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - CHAP
A1  - Dikta, Gerhard
T1  - Fundamentals of applied probability and basic statistics
T2  - Critical care nephrology / [Hrsg.:] Claudio Ronco and Rinaldo Bellomo
Y1  - 1998
SN  - 978-94-010-6306-7
SP  - 51
EP  - 61
PB  - Springer
CY  - Dordrecht
ER  - 
TY  - CHAP
A1  - Bialonski, Stephan
T1  - Are interaction clusters in epileptic networks predictive of seizures?
T2  - Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics
Y1  - 2016
SN  - 978-143983886-0
SP  - 349
EP  - 355
PB  - CRC Press
ER  - 
TY  - CHAP
A1  - Bialonski, Stephan
A1  - Lehnertz, Klaus
T1  - From time series to complex networks: an overview
T2  - Recent Advances in Predicting and Preventing Epileptic Seizures: Proceedings of the 5th International Workshop on Seizure Prediction
N2  - The network approach towards the analysis of the dynamics of complex systems has been successfully applied in a multitude of studies in the neurosciences and has yielded fascinating insights. With this approach, a complex system is considered to be composed of different constituents which interact with each other. Interaction structures can be compactly represented in interaction networks. In this contribution, we present a brief overview about how interaction networks are derived from multivariate time series, about basic network characteristics, and about challenges associated with this analysis approach.
Y1  - 2013
SN  - 978-981-4525-36-7
U6  - https://doi.org/10.1142/9789814525350_0010
SP  - 132
EP  - 147
ER  - 
TY  - CHAP
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - Uncertainty multimode failure and shakedown analysis of shells
T2  - Direct methods for limit and shakedown analysis of structures / eds. Paolo Fuschi ...
N2  - This paper presents a numerical procedure for reliability analysis of thin plates and shells with respect to plastic collapse or to inadaptation. The procedure involves a deterministic shakedown analysis for each probabilistic iteration, which is based on the upper bound approach and the use of the exact Ilyushin yield surface. Probabilistic shakedown analysis deals with uncertainties originated from the loads, material strength and thickness of the shell. Based on a direct definition of the limit state function, the calculation of the failure probability may be efficiently solved by using the First and Second Order Reliability Methods (FORM and SORM). The problem of reliability of structural systems (series systems) is handled by the application of a special technique which permits to find all the design points corresponding to all the failure modes. Studies show, in this case, that it improves considerably the FORM and SORM results.
KW  - Limit analysis
KW  - Shakedown analysis
KW  - Reliability analysis
KW  - Multimode failure
KW  - Non-linear optimization
Y1  - 2015
SN  - 978-3-319-12927-3 (print) ; 978-3-319-12928-0 (online)
U6  - https://doi.org/10.1007/978-3-319-12928-0_14
SP  - 279
EP  - 298
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Tran, Thanh Ngoc
A1  - Staat, Manfred
T1  - Shakedown analysis of Reissner-Mindlin plates using the edge-based smoothed finite element method
T2  - Direct methods for limit states in structures and materials / Dieter Weichert ; Alan Ponter, ed.
N2  - This paper concerns the development of a primal-dual algorithm for limit and shakedown analysis of Reissner-Mindlin plates made of von Mises material. At each optimization iteration, the lower bound of the shakedown load multiplier is calculated simultaneously with the upper bound using the duality theory. An edge-based smoothed finite element method (ES-FEM) combined with the discrete shear gap (DSG) technique is used to improve the accuracy of the solutions and to avoid the transverse shear locking behaviour. The method not only possesses all inherent features of convergence and accuracy from ES-FEM, but also ensures that the total number of variables in the optimization problem is kept to a minimum compared with the standard finite element formulation. Numerical examples are presented to demonstrate the effectiveness of the present method.
Y1  - 2014
SN  - 978-94-007-6826-0 (Print) 978-94-007-6827-7 (Online)
U6  - https://doi.org/10.1007/978-94-007-6827-7_5
SP  - 101
EP  - 117
PB  - Springer
CY  - Dordrecht [u.a.]
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Heitzer, Michael
ED  - Staat, Manfred
ED  - Heitzer, Michael
T1  - Probabilistic limit and shakedown problems
T2  - Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems
Y1  - 2003
SN  - 3-00-010001-6
N1  - NIC Series
VL  - 15
SP  - 217
EP  - 268
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - CHAP
A1  - Tran, N. T.
A1  - Tran, Thanh Ngoc
A1  - Matthies, M. G.
A1  - Stavroulakis, G. E.
A1  - Staat, Manfred
T1  - Shakedown Analysis Under Stochastic Uncertainty by Chance Constrained Programming
T2  - Advances in Direct Methods for Materials and Structures
N2  - In this paper we propose a stochastic programming method to analyse limit and shakedown of structures under uncertainty condition of strength. Based on the duality theory, the shakedown load multiplier formulated by the kinematic theorem is proved actually to be the dual form of the shakedown load multiplier formulated by static theorem. In this investigation a dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) with three-node linear triangular elements is used for structural analysis.
Y1  - 2017
SN  - 978-3-319-59810-9
U6  - https://doi.org/10.1007/978-3-319-59810-9_6
SP  - 85
EP  - 103
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Knott, Thomas C.
A1  - Sofronia, Raluca E.
A1  - Gerressen, Marcus
A1  - Law, Yuen
A1  - Davidescu, Arjana
A1  - Savii, George G.
A1  - Gatzweiler, Karl-Heinz
A1  - Staat, Manfred
A1  - Kuhlen, Torsten W.
T1  - Preliminary bone sawing model for a virtual reality-based training simulator of bilateral sagittal split osteotomy
T2  - Biomedical simulation : 6th International Symposium, ISBMS 2014, Strasbourg, France, October 16-17, 2014 : proceedings (Lecture notes in computer science : vol. 8789)
N2  - Successful bone sawing requires a high level of skill and experience, which could be gained by the use of Virtual Reality-based simulators. A key aspect of these medical simulators is realistic force feedback. The aim of this paper is to model the bone sawing process in order to develop a valid training simulator for the bilateral sagittal split osteotomy, the most often applied corrective surgery in case of a malposition of the mandible. Bone samples from a human cadaveric mandible were tested using a designed experimental system. Image processing and statistical analysis were used for the selection of four models for the bone sawing process. The results revealed a polynomial dependency between the material removal rate and the applied force. Differences between the three segments of the osteotomy line and between the cortical and cancellous bone were highlighted.
KW  - Bone sawing
KW  - virtual reality
KW  - training simulator
Y1  - 2014
SN  - 978-3-319-12057-7 (Online)
SN  - 978-3-319-12056-0 (Print)
U6  - https://doi.org/10.1007/978-3-319-12057-7_1
SP  - 1
EP  - 10
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Digel, Ilya
A1  - Akimbekov, Nuraly S.
A1  - Kistaubayeva, Aida
A1  - Zhubanova, Azhar A.
ED  - Artmann, Gerhard
ED  - Temiz Artmann, Aysegül
ED  - Zhubanova, Azhar A.
ED  - Digel, Ilya
T1  - Microbial Sampling from Dry Surfaces: Current Challenges and Solutions
T2  - Biological, Physical and Technical Basics of Cell Engineering
N2  - Sampling of dry surfaces for microorganisms is a main component of microbiological safety and is of critical importance in many fields including epidemiology, astrobiology as well as numerous branches of medical and food manufacturing. Aspects of biofilm formation, analysis and removal in aqueous solutions have been thoroughly discussed in literature. In contrast, microbial communities on air-exposed (dry) surfaces have received significantly less attention. Diverse surface sampling methods have been developed in order to address various surfaces and microbial groups, but they notoriously show poor repeatability, low recovery rates and suffer from lack of mutual consistency. Quantitative sampling for viable microorganisms represents a particular challenge, especially on porous and irregular surfaces. Therefore, it is essential to examine in depth the factors involved in microorganisms’ recovery efficiency and accuracy depending on the sampling technique used. Microbial colonization, retention and community composition on different dry surfaces are very complex and rely on numerous physicochemical and biological factors. This study is devoted to analyze and review the (a) physical phenomena and intermolecular forces relevant for microbiological surface sampling; (b) challenges and problems faced by existing sampling methods for viable microorganisms and (c) current directions of engineering and research aimed at improvement of quality and efficiency of microbiological surface sampling.
KW  - Sampling methods
KW  - Surface microorganisms
KW  - Dry surfaces
KW  - Microbial adhesion
KW  - Swabbing
Y1  - 2018
SN  - 978-981-10-7904-7
U6  - https://doi.org/10.1007/978-981-10-7904-7_19
SP  - 421
EP  - 456
PB  - Springer
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Staat, Manfred
A1  - Heitzer, M.
T1  - Basis reduction technique for limit and shakedown problems
T2  - Numerical Methods for Limit and Shakedown Analysis. Deterministic and Probabilistic Approach. NIC Series Vol. 15 / Ed. by Staat, M.; Heitzer, M.
Y1  - 2003
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0001-2018112115
SN  - 3-00-010001-6
SP  - 1
EP  - 55
PB  - John von Neumann Institute for Computing (NIC)
CY  - Jülich
ER  - 
TY  - CHAP
A1  - Osterhage, Hannes
A1  - Bialonski, Stephan
A1  - Staniek, Matthäus
A1  - Schindler, Kaspar
A1  - Wagner, Tobias
A1  - Elger, Christian E.
A1  - Lehnertz, Klaus
T1  - Bivariate and multivariate time series analysis techniques and their potential impact for seizure prediction
T2  - Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications
Y1  - 2008
SN  - 978-3-527-62519-2
U6  - https://doi.org/10.1002/9783527625192.ch15
SP  - 189
EP  - 208
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Bozakov, Zdravko
A1  - Sander, Volker
T1  - OpenFlow: A Perspective for Building Versatile Networks
T2  - Network-Embedded Management and Applications
Y1  - 2013
SN  - 978-1-4419-6769-5
U6  - https://doi.org/10.1007/978-1-4419-6769-5_11
SP  - 217
EP  - 245
PB  - Springer
CY  - New York, NY
ER  - 
TY  - CHAP
A1  - Kotliar, Konstantin
ED  - Pallikaris, I.
ED  - Tsilimbaris, M. K.
ED  - Dastiridou, A. I.
T1  - Ocular rigidity: clinical approach
T2  - Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye
N2  - The term ocular rigidity is widely used in clinical ophthalmology. Generally it is assumed as a resistance of the whole eyeball to mechanical deformation and relates to biomechanical properties of the eye and its tissues. Basic principles and formulas for clinical tonometry, tonography and pulsatile ocular blood flow measurements are based on the concept of ocular rigidity. There is evidence for altered ocular rigidity in aging, in several eye diseases and after eye surgery. Unfortunately, there is no consensual view on ocular rigidity: it used to make a quite different sense for different people but still the same name. Foremost there is no clear consent between biomechanical engineers and ophthalmologists on the concept. Moreover ocular rigidity is occasionally characterized using various parameters with their different physical dimensions. In contrast to engineering approach, clinical approach to ocular rigidity claims to characterize the total mechanical response of the eyeball to its deformation without any detailed considerations on eye morphology or material properties of its tissues. Further to the previous chapter this section aims to describe clinical approach to ocular rigidity from the perspective of an engineer in an attempt to straighten out this concept, to show its advantages, disadvantages and various applications.
KW  - Coefficient of ocular rigidity
KW  - Eyeball
KW  - Corneo-scleral shell
KW  - Pressure-volume relationship
KW  - Differential tonometry
Y1  - 2021
SN  - 978-3-030-64422-2
U6  - https://doi.org/10.1007/978-3-030-64422-2_2
SP  - 15
EP  - 43
PB  - Springer
CY  - Cham
ER  - 
TY  - CHAP
A1  - Akimbekov, Nuraly S.
A1  - Zhanadilovna, Abdieva G.
A1  - Ualieva, Perizat S.
A1  - Abaihanovna, Zhusipova D.
A1  - Digel, Ilya
A1  - Savitskaya, Irina S.
A1  - Zhubanova, Azhar Achmet
T1  - Functionalization of Carbon Based Wound Dressings with Antimicrobial Phytoextracts for Bioactive Treatment of Septic Wounds
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - The treatment of septic wounds with curative dressings based on biocomposites containing sage and marigold phytoextracts was effective in in vitro and in vivo experiments. These dressings caused the purification of the wound surface from purulent-necrotic masses three days earlier than in the other experimental groups. The consequence of an increase in incidents of severe course of the wound and the observed tendency to increase the number of adverse effects is the development of long-term recurrent wound processes. To treat purulent wounds, the following tactics were used: The purulent wounds of animals were covered with the examined wound dressing, and then the next day samples were taken, the procedure was performed once in 2 days. To obtain the active nanostructured sorbents such as carbonized rice husks, they are functionalized with biologically active components possessing antimicrobial, anti-inflammatory, antitoxic, immunomodulating, antiallergic and other types of properties.
Y1  - 2020
SN  - 978-981-4800-27-3
U6  - https://doi.org/10.1201/9780429428647-11
SP  - 211
EP  - 228
PB  - Jenny Stanford Publishing
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Savitskaya, Irina S.
A1  - Kistaubayeva, Aida S.
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Shokatayeva, Dina
A1  - Zhubanova, Azhar Achmet
T1  - Prospective Use of Probiotics Immobilized on Sorbents with Nanostructured Surfaces
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - Activated carbons are known as excellent adsorbents. Their applications include the adsorptive removal of color, odor, taste, undesirable organic and inorganic pollutants from drinking and waste water; air purification in inhabited spaces; purification of many chemicals, pharmaceutical products and many others. This chapter elucidates the role of normal microflora in the maintenance of human health and presents materials on possible clinical displays of microecological infringements and ways of their correction. It presents new developments concerning new probiotics with immobilized Lactobacillus and Bacillus. The chapter considers the mechanisms of the intestine disbacteriosis correction by sorbed probiotics. It demonstrates the advantages and creation prospects of immobilized probiotics developed on the basis of carbonized rice husk. There are great prospects for the development of medical biotechnology due to use of carbon sorbents with a nanostructured surface. Microbial communities form a biocenosis of the biotope and together with the host organism create permanent or temporary ecosystems.
Y1  - 2020
SN  - 978-981-4800-27-3
U6  - https://doi.org/10.1201/9780429428647-12
SP  - 229
EP  - 267
PB  - Jenny Stanford Publishing
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Zhubanova, Azhar A.
A1  - Mansurov, Zulkhair A.
A1  - Digel, Ilya
T1  - Use of Advanced Nanomaterials for Bioremediation of Contaminated Ecosystems
T2  - Carbon Nanomaterials in Biomedicine and the Environment
N2  - This chapter shows that nanomaterials obtained by high-temperature carbonization of inexpensive plant raw material such as rice husk, grape seeds, and walnut shells can serve as a basis for the production of highly efficient microbial drugs, biodestructors, biosorbents, and biocatalysts, which are promising for the remediation of the ecosystem contaminated with heavy and radioactive metals, oil and oil products. A strong interest in engineering zymology is dictated by the necessity to address the issues of monitoring enzymatic processes, treatment, and diagnosis of a number of common human diseases, environmental pollution, quality control of pharmaceuticals and food. Nanomaterials obtained by high-temperature carbonization of cheap plant raw material such as-rice husks, grape seeds and walnut shells, can serve as a basis for creating of highly effective microbial preparations-biodestructors, biosorbents and biocatalysts, which are promising for the use of contaminated ecosystems, and for restoration of human intestine microecology.
Y1  - 2020
SN  - 978-981-4800-27-3
U6  - https://doi.org/10.1201/9780429428647-18
SP  - 353
EP  - 378
PB  - Jenny Stanford Publishing
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Razzaque, Mohammed S.
T1  - Role of vitamins in maintaining structure and function of intestinal microbiome
T2  - Comprehensive Gut Microbiota
N2  - The recent advances in microbiology have shed light on understanding the role of vitamins beyond the nutritional range. Vitamins are critical in contributing to healthy biodiversity and maintaining the proper function of gut microbiota. The sharing of vitamins among bacterial populations promotes stability in community composition and diversity; however, this balance becomes disturbed in various pathologies. Here, we overview and analyze the ability of different vitamins to selectively and specifically induce changes in the intestinal microbial community. Some schemes and regularities become visible, which may provide new insights and avenues for therapeutic management and functional optimization of the gut microbiota.
KW  - Vitamin A
KW  - Vitamin B
KW  - Thiamine
KW  - Riboflavin
KW  - Niacin
Y1  - 2022
SN  - 978-0-12-822036-8
U6  - https://doi.org/10.1016/B978-0-12-819265-8.00043-7
SP  - 320
EP  - 334
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - CHAP
A1  - Akimbekov, Nuraly S.
A1  - Digel, Ilya
A1  - Sherelkhan, Dinara K.
A1  - Razzaque, Mohammed S.
T1  - Vitamin D and Phosphate Interactions in Health and Disease
T2  - Phosphate Metabolism
N2  - Vitamin D plays an essential role in calcium and inorganic phosphate (Pi) homeostasis, maintaining their optimal levels to assure adequate bone mineralization. Vitamin D, as calcitriol (1,25(OH)2D), not only increases intestinal calcium and phosphate absorption but also facilitates their renal reabsorption, leading to elevated serum calcium and phosphate levels. The interaction of 1,25(OH)2D with its receptor (VDR) increases the efficiency of intestinal absorption of calcium to 30–40% and phosphate to nearly 80%. Serum phosphate levels can also influence 1,25 (OH)2D and fibroblast growth factor 23 (FGF23) levels, i.e., higher phosphate concentrations suppress vitamin D activation and stimulate parathyroid hormone (PTH) release, while a high FGF23 serum level leads to reduced vitamin D synthesis. In the vitamin D-deficient state, the intestinal calcium absorption decreases and the secretion of PTH increases, which in turn causes the stimulation of 1,25(OH)2D production, resulting in excessive urinary phosphate loss. Maintenance of phosphate homeostasis is essential as hyperphosphatemia is a risk factor of cardiovascular calcification, chronic kidney diseases (CKD), and premature aging, while hypophosphatemia is usually associated with rickets and osteomalacia. This chapter elaborates on the possible interactions between vitamin D and phosphate in health and disease.
KW  - Vitamin D
KW  - PTH
KW  - Phosphate
KW  - FGF23
KW  - Klotho
Y1  - 2022
SN  - 978-3-030-91621-3
U6  - https://doi.org/10.1007/978-3-030-91623-7_5
SP  - 37
EP  - 46
PB  - Springer
CY  - Cham
ER  -