TY  - JOUR
A1  - Kopp, Alexander
A1  - Schunck, Laura
A1  - Gosau, Martin
A1  - Smeets, Ralf
A1  - Burg, Simon
A1  - Fuest, Sandra
A1  - Kröger, Nadja
A1  - Zinser, Max
A1  - Krohn, Sebastian
A1  - Behbahani, Mehdi
A1  - Köpf, Marius
A1  - Lauts, Lisa
A1  - Rutkowski, Rico
T1  - Influence of the casting concentration on the mechanical and optical properties of Fa/CaCl2-derived silk fibroin membranes
JF  - International Journal of Molecular Sciences
N2  - In this study, we describe the manufacturing and characterization of silk fibroin membranes derived from the silkworm Bombyx mori. To date, the dissolution process used in this study has only been researched to a limited extent, although it entails various potential advantages, such as reduced expenses and the absence of toxic chemicals in comparison to other conventional techniques. Therefore, the aim of this study was to determine the influence of different fibroin concentrations on the process output and resulting membrane properties. Casted membranes were thus characterized with regard to their mechanical, structural and optical assets via tensile testing, SEM, light microscopy and spectrophotometry. Cytotoxicity was evaluated using BrdU, XTT, and LDH assays, followed by live–dead staining. The formic acid (FA) dissolution method was proven to be suitable for the manufacturing of transparent and mechanically stable membranes. The fibroin concentration affects both thickness and transparency of the membranes. The membranes did not exhibit any signs of cytotoxicity. When compared to other current scientific and technical benchmarks, the manufactured membranes displayed promising potential for various biomedical applications. Further research is nevertheless necessary to improve reproducible manufacturing, including a more uniform thickness, less impurity and physiological pH within the membranes.
Y1  - 2020
U6  - http://dx.doi.org/10.3390/ijms21186704
SN  - 1422-0067
N1  - Special issue: Optimization of Biomaterials for Reconstructive and Regenerative Medicine
VL  - 21
IS  - 18 art. no. 6704
PB  - MDPI
CY  - Basel
ER  - 
TY  - THES
A1  - Kotliar, Konstantin
T1  - Pathophysiologische Beurteilung und hämodynamische Analyse von mikrostrukturellen Veränderungen des retinalen Gefäßlängsschnittsprofils
Y1  - 2012
N1  - Moskau, Habil.-Schr. ,Russ. Univ., Med. Fakultät, 2012. Originaltitel in Russisch.
ER  - 
TY  - THES
A1  - Kotliar, Konstantin
T1  - Functional in-vivo assessment and biofluidmechanical analysis of age-related and pathological microstructural changes in retinal vessels [Elektronische Ressource]
Y1  - 2008
N1  - München, Techn. Univ., Diss., 2008
PB  - -
ER  - 
TY  - THES
A1  - Kotliar, Konstantin
T1  - Razrabotka i analiz matematicheskih modelei nezavisimogo i svyazannogo funkcionirovaniya drenazhnoi i akkomodacionnoi regulyatornyh sistem chelovecheskogo glaza
T2  - Mathematische Modelle der interaktiven und unabhängigen Funktion von Drainage- und Akkommodations-Regelungssystemen des menschlichen Auges
Y1  - 1998
N1  - St.-Petersburg, Russland, Univ., Diss., 1998 
[Lehrstuhl für Theoretische Mechanik der
Staatlichen Polytechnischen Universität St.-Petersburg] 
Originaltitel: Razrabotka i analiz
matematicheskih modelei nezavisimogo i svyazannogo funkcionirovaniya
drenazhnoi i akkomodacionnoi regulyatornyh sistem chelovecheskogo
glaza. 328 S.
PB  - -
ER  - 
TY  - THES
A1  - Kotliar, Konstantin
T1  - Dynamische retinale Gefäßanalyse für die Diagnostik und Früherkennung von System- und Augenerkrankungen vaskulärer Genese
Y1  - 2013
N1  - München, Techn. Univ., Habil.-Schrift, 2013
ER  - 
TY  - CHAP
A1  - Kotliar, Konstantin
ED  - Pallikaris, I.
ED  - Tsilimbaris, M. K.
ED  - Dastiridou, A. I.
T1  - Ocular rigidity: clinical approach
T2  - Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye
N2  - The term ocular rigidity is widely used in clinical ophthalmology. Generally it is assumed as a resistance of the whole eyeball to mechanical deformation and relates to biomechanical properties of the eye and its tissues. Basic principles and formulas for clinical tonometry, tonography and pulsatile ocular blood flow measurements are based on the concept of ocular rigidity. There is evidence for altered ocular rigidity in aging, in several eye diseases and after eye surgery. Unfortunately, there is no consensual view on ocular rigidity: it used to make a quite different sense for different people but still the same name. Foremost there is no clear consent between biomechanical engineers and ophthalmologists on the concept. Moreover ocular rigidity is occasionally characterized using various parameters with their different physical dimensions. In contrast to engineering approach, clinical approach to ocular rigidity claims to characterize the total mechanical response of the eyeball to its deformation without any detailed considerations on eye morphology or material properties of its tissues. Further to the previous chapter this section aims to describe clinical approach to ocular rigidity from the perspective of an engineer in an attempt to straighten out this concept, to show its advantages, disadvantages and various applications.
KW  - Coefficient of ocular rigidity
KW  - Eyeball
KW  - Corneo-scleral shell
KW  - Pressure-volume relationship
KW  - Differential tonometry
Y1  - 2021
SN  - 978-3-030-64422-2
U6  - http://dx.doi.org/10.1007/978-3-030-64422-2_2
SP  - 15
EP  - 43
PB  - Springer
CY  - Cham
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Bauer, S. M.
A1  - Zamuraev, L. A.
T1  - Model of the transversely isotropic spherical layer for estimation of intraocular pressure changes after intravitreal injections / Bauer, S. M. ; Zamuraev, L. A. ; Kotliar, K. E.
JF  - Rossiiskii zhurnal biomekhaniki = Russian Journal of biomechanics. 10 (2006), H. 2
Y1  - 2006
SN  - 1812-5123
SP  - 41
EP  - 47
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Baumann, Marcus
A1  - Vilser, Walthard
A1  - Lanzl, Ines M.
T1  - Pulse wave velocity in retinal arteries of healthy volunteers
JF  - British Journal of Ophthalmology (eBJO)
Y1  - 2011
SN  - 1468-2079
VL  - 95
IS  - 11
SP  - 675
EP  - 679
PB  - BMJ Publ. Group
CY  - London
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment.
 Part I. Ocular blood circulation and its quantitative estimation
JF  - National journal Glaucoma
Y1  - 2006
SN  - 2078-4104
VL  - Vol. 5
IS  - No. 3
SP  - 62
EP  - 73
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part III. Non-invasive methods of assessment of ocular blood flow. 2. Static and dynamic assessment of retinal vessel reaction to stimuli
JF  - National Journal Glaucoma
Y1  - 2007
SN  - 2078-4104
VL  - Vol. 6
IS  - No. 2
SP  - 64
EP  - 71
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part III. Non-invasive methods of assessment of ocular blood flow. 1. Assessment of blood cell velocities and flow rates in intraocular vessels and vascular beds
JF  - Journal of Glaucoma
Y1  - 2007
SN  - 2078-4104
VL  - Vol. 6
IS  - 1
SP  - 61
EP  - 68
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Drozdova, G. A.
A1  - Shamshinova, A. M.
T1  - Ocular hemodinamics and contemporary methods of its assessment. Part II. Invasive methods of assessment of ocular blood flow
JF  - National Journal Glaucoma
Y1  - 2006
SN  - 2078-4104
VL  - Vol. 5
IS  - No. 4
SP  - 37
EP  - 49
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Hanssen, Henner
A1  - Eberhardt, Karla
A1  - Vilser, Walthard
A1  - Schmaderer, Christoph
A1  - Halle, Martin
A1  - Heemann, Uwe
A1  - Baumann, M.
T1  - Retinal pulse wave velocity in young male normotensive and mildly hypertensive subjects
JF  - Microcirculation
Y1  - 2013
SN  - 1549-8719
N1  - Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.)
PB  - Wiley
CY  - Malden
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Hauser, Christine
A1  - Ortner, Marion
A1  - Muggenthaler, Claudia
A1  - Diehl-Schmid, Janine
A1  - Angermann, Susanne
A1  - Hapfelmeier, Alexander
A1  - Schmaderer, Christoph
A1  - Grimmer, Timo
T1  - Altered neurovascular coupling as measured by optical imaging: a biomarker for Alzheimer’s disease
JF  - Scientific Reports
Y1  - 2017
U6  - http://dx.doi.org/10.1038/s41598-017-13349-5
SN  - 2045-2322
N1  - Article 12906
VL  - 7
IS  - 1
SP  - 1
EP  - 11
PB  - Springer Nature
CY  - Cham
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Kharoubi, A.
A1  - Schmidt-Trucksäß, A.
A1  - Halle, M.
A1  - Lanzl, I.
T1  - Does internal longitudinal microstructure of retinal veins change with age in medically healthy persons?
JF  - Acta Ophthalmologica
Y1  - 2009
SN  - 1600-0420 (E-Journal); 1755-3768 (E-Journal); 0001-639X (Print); 1395-3907 (Print); 1755-375X (Print)
VL  - Vol. 87
IS  - Suppl. S244
SP  - 0
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlova, O. V.
A1  - Zaseeva, M. V.
T1  - Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part I Initial theoretical presuppositions, hypotheses and facts / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotli
JF  - Glaukoma (2006)
Y1  - 2006
N1  - Original in Russisch
SP  - 35
EP  - 53
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlowa, O. V.
A1  - Makarov, F. N.
T1  - Biomechanical analysis of traditional and contemporary conceptions on pathogenesis of the primary open angle glaucoma / Koshitz, I. N. ; Svetlova, O. V. ; Kotliar, K. E. ; Makarov, F. N. ;  Smolnikov, B. A.
JF  - Glaukoma (2005)
Y1  - 2005
N1  - Original in Russisch
SP  - 41
EP  - 63
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Koshitz, I. N.
A1  - Svetlowa, O. V.
A1  - Zaseeva, M. V.
T1  - Physiological principles of hypotensive therapy of open-angle glaucoma during presbyopic period. Part II Promising algorithms of practical sparing applications / Koshitz, I. N. ; Svetlova, O. V. ; Zaseeva, M. V. ; Shuhaev, S. V. ; Makarov, F. N. ; Kotliar
JF  - Glaukoma (2006)
Y1  - 2006
N1  - Original in Russisch
SP  - 51
EP  - 70
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Kozlova, Tatiana V.
A1  - Lanzl, Ines M.
T1  - Postoperative aqueous outflow in the human eye after glaucoma filtration surgery: biofluidmechanical considerations
JF  - Biomedizinische Technik = Biomedical Engineering
Y1  - 2009
SN  - 1862-278X
VL  - 54
IS  - 1
SP  - 14
EP  - 22
PB  - -
ER  - 
TY  - JOUR
A1  - Kotliar, Konstantin
A1  - Lanzl, I. M.
T1  - Biomechanical modeling of the aqueous humor outflow after non-penetrating glaucoma filtration surgery in the human eye
JF  - Acta of bioengineering and biomechanics
Y1  - 2002
SN  - 1509-409X
VL  - Vol. 4
IS  - Suppl. 1
SP  - 728
EP  - 729
ER  -