TY - JOUR A1 - Kurowski, A. A1 - Schultze, J. A1 - Lüth, H. A1 - Schöning, Michael Josef T1 - Micro- and nanopatterning of sensor chips by means of macroporous silicon. JF - Sensors and Actuators B. 83 (2002), H. 1-3 Y1 - 2002 SN - 0925-4005 N1 - Selected Papers from TRANSDUCERS '01 EUROSENSORS XV SP - 123 EP - 128 ER - TY - JOUR A1 - Kuhnert, Marie-Therese A1 - Bialonski, Stephan A1 - Noenning, Nina A1 - Mai, Heinke A1 - Hinrichs, Hermann A1 - Helmstaedter, Christoph A1 - Lehnertz, Klaus T1 - Incidental and intentional learning of verbal episodic material differentially modifies functional brain networks JF - Plos one N2 - Learning- and memory-related processes are thought to result from dynamic interactions in large-scale brain networks that include lateral and mesial structures of the temporal lobes. We investigate the impact of incidental and intentional learning of verbal episodic material on functional brain networks that we derive from scalp-EEG recorded continuously from 33 subjects during a neuropsychological test schedule. Analyzing the networks' global statistical properties we observe that intentional but not incidental learning leads to a significantly increased clustering coefficient, and the average shortest path length remains unaffected. Moreover, network modifications correlate with subsequent recall performance: the more pronounced the modifications of the clustering coefficient, the higher the recall performance. Our findings provide novel insights into the relationship between topological aspects of functional brain networks and higher cognitive functions. Y1 - 2013 U6 - http://dx.doi.org/10.1371/journal.pone.0080273 VL - 8 IS - 11 PB - PLOS CY - San Francisco ER - TY - CHAP A1 - Kuhlen, Max A1 - Digel, Ilya ED - Erni, Daniel ED - Fischerauer, Alice ED - Himmel, Jörg ED - Seeger, Thomas ED - Thelen, Klaus T1 - Fluorescence signatures and detection limits of ubiquitous terrestrial bio-compounds T2 - 2nd YRA MedTech Symposium 2017 : June 8th - 9th / 2017 / Hochschule Ruhr-West Y1 - 2017 SN - 978-3-9814801-9-1 U6 - http://dx.doi.org/10.17185/duepublico/43984 N1 - A young researchers track of the 7th IEEE Workshop & SENSORICA 2017 SP - 102 EP - 103 PB - Universität Duisburg-Essen CY - Duisburg ER - TY - JOUR A1 - Kuerten, David A1 - Kotliar, Konstantin A1 - Fuest, Matthias A1 - Walter, Peter A1 - Hollstein, Muriel A1 - Plange, Niklas ED - Neri, Piergiorgio T1 - Does hemispheric vascular regulation differ significantly in glaucoma patients with altitudinal visual field asymmetry? A single-center, prospective study JF - International Ophthalmology N2 - Purpose Vascular risk factors and ocular perfusion are heatedly discussed in the pathogenesis of glaucoma. The retinal vessel analyzer (RVA, IMEDOS Systems, Germany) allows noninvasive measurement of retinal vessel regulation. Significant differences especially in the veins between healthy subjects and patients suffering from glaucoma were previously reported. In this pilot-study we investigated if localized vascular regulation is altered in glaucoma patients with altitudinal visual field defect asymmetry. Methods 15 eyes of 12 glaucoma patients with advanced altitudinal visual field defect asymmetry were included. The mean defect was calculated for each hemisphere separately (-20.99 ± 10.49 pro- found hemispheric visual field defect vs -7.36 ± 3.97 dB less profound hemisphere). After pupil dilation, RVA measurements of retinal arteries and veins were conducted using the standard protocol. The superior and inferior retinal vessel reactivity were measured consecutively in each eye. Results Significant differences were recorded in venous vessel constriction after flicker light stimulation and overall amplitude of the reaction (p \ 0.04 and p \ 0.02 respectively) in-between the hemispheres spheres. Vessel reaction was higher in the hemisphere corresponding to the more advanced visual field defect. Arterial diameters reacted similarly, failing to reach statistical significance. Conclusion Localized retinal vessel regulation is significantly altered in glaucoma patients with asymmetri altitudinal visual field defects. Veins supplying the hemisphere concordant to a less profound visual field defect show diminished diameter changes. Vascular dysregulation might be particularly important in early glaucoma stages prior to a significant visual field defect. KW - Glaucoma KW - Visual field asymmetry KW - Ocular blood flow KW - RVA KW - Vascular response Y1 - 2021 SN - 1573-2630 U6 - http://dx.doi.org/10.1007/s10792-021-01876-0 VL - 41 IS - 41 SP - 3109 EP - 3119 PB - Springer CY - Berlin ER - TY - JOUR A1 - Kuchler, Timon A1 - Günthner, Roman A1 - Ribeiro, Andrea A1 - Hausinger, Renate A1 - Streese, Lukas A1 - Wöhnl, Anna A1 - Kesseler, Veronika A1 - Negele, Johanna A1 - Assali, Tarek A1 - Carbajo-Lozoya, Javier A1 - Lech, Maciej A1 - Adorjan, Kristina A1 - Stubbe, Hans Christian A1 - Hanssen, Henner A1 - Kotliar, Konstantin A1 - Haller, Berhard A1 - Heemann, Uwe A1 - Schmaderer, Christoph T1 - Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation N2 - Background Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily life of patients. Understanding the pathophysiology of PCS is a public health priority, as it still poses a diagnostic and treatment challenge for physicians. Methods In this prospective observational cohort study, we analyzed the retinal microcirculation using Retinal Vessel Analysis (RVA) in a cohort of patients with PCS and compared it to an age- and gender-matched healthy cohort (n = 41, matched out of n = 204). Measurements and main results PCS patients exhibit persistent endothelial dysfunction (ED), as indicated by significantly lower venular flicker-induced dilation (vFID; 3.42% ± 1.77% vs. 4.64% ± 2.59%; p = 0.02), narrower central retinal artery equivalent (CRAE; 178.1 [167.5–190.2] vs. 189.1 [179.4–197.2], p = 0.01) and lower arteriolar-venular ratio (AVR; (0.84 [0.8–0.9] vs. 0.88 [0.8–0.9], p = 0.007). When combining AVR and vFID, predicted scores reached good ability to discriminate groups (area under the curve: 0.75). Higher PCS severity scores correlated with lower AVR (R = − 0.37 p = 0.017). The association of microvascular changes with PCS severity were amplified in PCS patients exhibiting higher levels of inflammatory parameters. Conclusion Our results demonstrate that prolonged endothelial dysfunction is a hallmark of PCS, and impairments of the microcirculation seem to explain ongoing symptoms in patients. As potential therapies for PCS emerge, RVA parameters may become relevant as clinical biomarkers for diagnosis and therapy management. KW - Endothelial dysfunction KW - Long COVID KW - Post-COVID-19 syndrome KW - retinal microvasculature Y1 - 2023 U6 - http://dx.doi.org/10.1007/s10456-023-09885-6 N1 - Corresponding author: Christoph Schmaderer VL - 26 SP - 547 EP - 563 PB - Springer Nature CY - Dordrecht ER - TY - JOUR A1 - Krämer, Melina A1 - Pita, Marcos A1 - Zhou, Jian A1 - Ornatska, Maryna A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny T1 - Coupling of Biocomputing Systems with Electronic Chips: Electronic Interface for Transduction of Biochemical Information JF - Journal of Physical Chemistry C: Nanomaterials and Interfaces. 113 (2009), H. 6 Y1 - 2009 SN - 1932-7455 SP - 2573 EP - 2579 PB - American Cemical Society CY - Washington, DC ER - TY - JOUR A1 - Krott, Daniel A1 - Gerhards, Michael A1 - Skorupa, Sascha A1 - Sander, Volker T1 - NHiLA - Bridging the Gap Between .NET and UNICORE JF - UNICORE Summit 2011 : proceedings, 7-8 July 2011, Torun, Poland / Mathilde Romberg ... (Eds.) Y1 - 2011 SN - 9783893367504 N1 - UNICORE Summit ; (2011 ; 2011.07.07-08 ; Torun) ; Schriften des Forschungszentrums Jülich IAS Series 9 SP - 77 EP - 86 PB - Forschungszentrum Jülich CY - Jülich ER - TY - CHAP A1 - Krome, Cornelia A1 - Sander, Volker T1 - Time series analysis with apache spark and its applications to energy informatics T2 - Proceedings of the 7th DACH+ Conference on Energy Informatics N2 - In energy economy forecasts of different time series are rudimentary. In this study, a prediction for the German day-ahead spot market is created with Apache Spark and R. It is just an example for many different applications in virtual power plant environments. Other examples of use as intraday price processes, load processes of machines or electric vehicles, real time energy loads of photovoltaic systems and many more time series need to be analysed and predicted. This work gives a short introduction into the project where this study is settled. It describes the time series methods that are used in energy industry for forecasts shortly. As programming technique Apache Spark, which is a strong cluster computing technology, is utilised. Today, single time series can be predicted. The focus of this work is on developing a method to parallel forecasting, to process multiple time series simultaneously with R and Apache Spark. Y1 - 2018 U6 - http://dx.doi.org/10.1186/s42162-018-0043-1 N1 - Energy Informatics 2018, Volume 1 Supplement 1 ER - TY - JOUR A1 - Krome, Cornelia A1 - Höft, Jan A1 - Sander, Volker T1 - Clustering time series applied to energy markets JF - Energy Informatics Y1 - 2019 U6 - http://dx.doi.org/10.1186/s42162-019-0076-0 SN - 2520-8942 VL - 2 IS - Article numer 17 SP - 1 EP - 20 PB - Springer CY - Berlin ER - TY - CHAP A1 - Kreutz, Christian A1 - Lörgen, Jürgen A1 - Graewe, Boris A1 - Bargon, Joachim A1 - Yoshida, Mayumi A1 - Freso, Zachary M. A1 - Frèchet, Jean M. J. T1 - High frequency quartz micro balances: a promising path to enhanced sensitivity of gravimetric sensors N2 - An array of 50 MHz quartz microbalances (QMBs) coated with a dendronized polymer was used to detect small amounts of volatile organic compounds (VOCs) in the gas phase. The results were compared to those obtained with the commonly used 10 MHz QMBs. The 50 MHz QMBs proved to be a powerful tool for the detection of VOCs in the gas phase; therefore, they represent a promising alternative to the much more delicate surface acoustic wave devices (SAWs). KW - Biosensor KW - Quartz micro balances KW - electronic noses dendronized polymers inverted mesa technology Y1 - 2006 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:hbz:a96-opus-1445 ER - TY - CHAP A1 - Kremers, Alexander A1 - Pieper, Martin T1 - Simulation and Verification of Bionic Heat Exchangers with COMSOL Multiphysics® Software T2 - COMSOL Conference 2015 User Presentations ; COMSOL Conference 2015 Grenoble October 14 - 16, 2015 - World Trade Center, Grenoble, France Y1 - 2015 PB - COMSOL CY - Göttingen ; Berlin ER - TY - JOUR A1 - Kramer, Friederike A1 - Halamkova, Lenka A1 - Poghossian, Arshak A1 - Schöning, Michael Josef A1 - Katz, Evgeny A1 - Halamek, Jan T1 - Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American JF - The analyst. August 2013 Y1 - 2013 SN - 1364-5528 (E-Journal); 0003-2654 (Print) VL - Vol. 138 SP - 6251 EP - 6257 PB - Royal Society of Chemistry CY - Cambridge ER - TY - CHAP A1 - Kraft, Bodo A1 - Wilhelms, Nils T1 - Visual Knowledge Specification for Conceptual Design N2 - Proc. of the 2005 ASCE Intl. Conf. on Computing in Civil Engineering (ICCC 2005) eds. L. Soibelman und F. Pena-Mora, Seite 1-14, ASCE (CD-ROM), Cancun, Mexico, 2005 Current CAD tools are not able to support the fundamental conceptual design phase, and none of them provides consistency analyses of sketches produced by architects. To give architects a greater support at the conceptual design phase, we develop a CAD tool for conceptual design and a knowledge specification tool allowing the definition of conceptually relevant knowledge. The knowledge is specific to one class of buildings and can be reused. Based on a dynamic knowledge model, different types of design rules formalize the knowledge in a graph-based realization. An expressive visual language provides a user-friendly, human readable representation. Finally, consistency analyses enable conceptual designs to be checked against this defined knowledge. In this paper we concentrate on the knowledge specification part of our project. KW - CAD KW - CAD KW - Bauingenieurwesen KW - CAD KW - civil engineering Y1 - 2005 ER - TY - CHAP A1 - Kraft, Bodo A1 - Wilhelms, N. T1 - Interactive distributed knowledge support for conceptual building design N2 - In: Net-distributed Co-operation : Xth International Conference on Computing in Civil and Building Engineering, Weimar, June 02 - 04, 2004 ; proceedings / [ed. by Karl Beuke ...] . - Weimar: Bauhaus-Univ. Weimar 2004. - 1. Aufl. . Seite 1-14 ISBN 3-86068-213-X International Conference on Computing in Civil and Building Engineering <10, 2004, Weimar> Summary In our project, we develop new tools for the conceptual design phase. During conceptual design, the coarse functionality and organization of a building is more important than a detailed worked out construction. We identify two roles, first the knowledge engineer who is responsible for knowledge definition and maintenance; second the architect who elaborates the conceptual de-sign. The tool for the knowledge engineer is based on graph technology, it is specified using PROGRES and the UPGRADE framework. The tools for the architect are integrated to the in-dustrial CAD tool ArchiCAD. Consistency between knowledge and conceptual design is en-sured by the constraint checker, another extension to ArchiCAD. KW - CAD KW - CAD KW - Bauingenieurwesen KW - CAD KW - civil engineering Y1 - 2004 SN - 3-86068-213-X ER - TY - CHAP A1 - Kraft, Bodo A1 - Schneider, Gerd T1 - Semantic Roomobjects for Conceptual Design Support : A Knowledge-based Approach N2 - In: Computer Aided Architectural Design Futures 2005 2005, Part 4, 207-216, DOI: http://dx.doi.org/10.1007/1-4020-3698-1_19 The conceptual design at the beginning of the building construction process is essential for the success of a building project. Even if some CAD tools allow elaborating conceptual sketches, they rather focus on the shape of the building elements and not on their functionality. We introduce semantic roomobjects and roomlinks, by way of example to the CAD tool ArchiCAD. These extensions provide a basis for specifying the organisation and functionality of a building and free architects being forced to directly produce detailed constructive sketches. Furthermore, we introduce consistency analyses of the conceptual sketch, based on an ontology containing conceptual relevant knowledge, specific to one class of buildings. KW - CAD KW - CAD KW - Bauingenieurwesen KW - CAD KW - civil engineering Y1 - 2005 SN - 978-1-4020-3460-2 ER - TY - CHAP A1 - Kraft, Bodo A1 - Retkowitz, Daniel T1 - Rule-Dependencies for Visual Knowledge Specification in Conceptual Design N2 - In: Proc. of the 11th Intl. Conf. on Computing in Civil and Building Engineering (ICCCBE-XI) ed. Hugues Rivard, Montreal, Canada, Seite 1-12, ACSE (CD-ROM), 2006 Currently, the conceptual design phase is not adequately supported by any CAD tool. Neither the support while elaborating conceptual sketches, nor the automatic proof of correctness with respect to effective restrictions is currently provided by any commercial tool. To enable domain experts to store the common as well as their personal domain knowledge, we develop a visual language for knowledge formalization. In this paper, a major extension to the already existing concepts is introduced. The possibility to define rule dependencies extends the expressiveness of the knowledge definition language and contributes to the usability of our approach. KW - CAD KW - CAD KW - Bauingenieurwesen KW - CAD KW - civil engineering Y1 - 2006 ER - TY - JOUR A1 - Kraft, Bodo A1 - Nobisrath, Ulrich A1 - Salumaa, Priit A1 - Schultchen, Erhard T1 - Fujaba based Tool Development for eHome Systems / Nobisrath, Ulrich ; Salumaa, Priit ; Schultchen, Erhard ; Kraft, Bodo JF - Electronic Notes in Theoretical Computer Science. 127 (2004), H. 1 Y1 - 2004 SN - 1571-0661 N1 - Proceedings of the International Workshop on Graph-Based Tools (GraBaTs 2004) SP - 89 EP - 99 ER - TY - JOUR A1 - Kraft, Bodo A1 - Nagl, Manfred T1 - Visual Knowledge Specification for Conceptual Design: Definition and Tool Support N2 - In: Advanced Engineering Informatics. Vol 21, Issue 1, 2007, Pages 67-83 http://dx.doi.org/10.1016/j.aei.2006.10.001 eds. J.C. Kunz, I.F.C. Smith and T. Tomiyama, Elsevier, Seite 1-22 Current CAD tools are not able to support the conceptual design phase, and none of them provides a consistency analysis for sketches produced by architects. This phase is fundamental and crucial for the whole design and construction process of a building. To give architects a better support, we developed a CAD tool for conceptual design and a knowledge specification tool. The knowledge is specific to one class of buildings and it can be reused. Based on a dynamic and domain-specific knowledge ontology, different types of design rules formalize this knowledge in a graph-based form. An expressive visual language provides a user-friendly, human readable representation. Finally, a consistency analysis tool enables conceptual designs to be checked against this formal conceptual knowledge. In this article, we concentrate on the knowledge specification part. For that, we introduce the concepts and usage of a novel visual language and describe its semantics. To demonstrate the usability of our approach, two graph-based visual tools for knowledge specification and conceptual design are explained. KW - CAD KW - CAD KW - Bauingenieurwesen KW - CAD KW - civil engineering Y1 - 2007 ER - TY - CHAP A1 - Kraft, Bodo A1 - Nagl, Manfred T1 - Semantic tool support for conceptual design N2 - ITCE-2003 - 4th Joint Symposium on Information Technology in Civil Engineering ed Flood, I., Seite 1-12, ASCE (CD-ROM), Nashville, USA In this paper we discussed graph based tools to support architects during the conceptual design phase. Conceptual Design is defined before constructive design; the used concepts are more abstract. We develop two graph based approaches, a topdown using the graph rewriting system PROGRES and a more industrially oriented approach, where we extend the CAD system ArchiCAD. In both approaches, knowledge can be defined by a knowledge engineer, in the top-down approach in the domain model graph, in the bottom-up approach in the in an XML file. The defined knowledge is used to incrementally check the sketch and to inform the architect about violations of the defined knowledge. Our goal is to discover design error as soon as possible and to support the architect to design buildings with consideration of conceptual knowledge. KW - CAD KW - CAD KW - Bauingenieurwesen KW - CAD KW - civil engineering Y1 - 2003 ER - TY - CHAP A1 - Kraft, Bodo A1 - Meyer, Oliver A1 - Nagl, Manfred T1 - Graph technology support for conceptual design in civil engineering N2 - In: Advances in intelligent computing in engineering : proceedings of the 9.International EG-ICE Workshop ; Darmstadt, (01 - 03 August) 2002 / Martina Schnellenbach-Held ... (eds.) . - Düsseldorf: VDI-Verl., 2002 .- Fortschritt-Berichte VDI, Reihe 4, Bauingenieurwesen ; 180 ; S. 1-35 The paper describes a novel way to support conceptual design in civil engineering. The designer uses semantical tools guaranteeing certain internal structures of the design result but also the fulfillment of various constraints. Two different approaches and corresponding tools are discussed: (a) Visually specified tools with automatic code generation to determine a design structure as well as fixing various constraints a design has to obey. These tools are also valuable for design knowledge specialist. (b) Extensions of existing CAD tools to provide semantical knowledge to be used by an architect. It is sketched how these different tools can be combined in the future. The main part of the paper discusses the concepts and realization of two prototypes following the two above approaches. The paper especially discusses that specific graphs and the specification of their structure are useful for both tool realization projects. KW - CAD KW - CAD ; KW - CAD KW - civil engineering Y1 - 2002 SN - 3-18-318004-9 ER -