TY - JOUR A1 - Lassonczyk, Beate A1 - Voigt, B. A1 - Gabriel, B. A1 - Ghod, Mumin M. T1 - Quaternary events at the Horn of Africa / Voigt, B., B. Gabriel, B. Lassonczyk and Mumin M. Ghod JF - Berliner geowissenschaftliche Abhandlungen / Reihe A, Geologie und Paläontologie / hrsg. von d. Geowissenschaftlichen Instituten der Freien u. d. Technischen Universität Berlin. 120 A (1990) Y1 - 1990 SN - 0172-8784 SP - 679 EP - 694 ER - TY - JOUR A1 - Lassonczyk, Beate A1 - Alaily, F. A1 - Huth, A. A1 - Gensior, A. T1 - Genesis of soils in the arid part of northeast Somalia / F. Alaily, B. Lassonczyk, A.Huth and A. Gensior JF - Berliner geowissenschaftliche Abhandlungen / Reihe A, Geologie und Paläontologie / hrsg. von d. Geowissenschaftlichen Instituten der Freien u. d. Technischen Universität Berlin. 120 A (1990) Y1 - 1990 SN - 0172-8784 SP - 695 EP - 711 ER - TY - JOUR A1 - Lassonczyk, Beate T1 - Characteristics of a fossil soil developed on the basement complex in the northeast Somalia JF - Berliner geowissenschaftliche Abhandlungen / Reihe A, Geologie und Paläontologie / hrsg. von d. Geowissenschaftlichen Instituten der Freien u. d. Technischen Universität Berlin. 120 A (1990) Y1 - 1990 SN - 0172-8784 SP - 713 EP - 718 ER - TY - JOUR A1 - Lapitan, Denis G. A1 - Rogatkin, Dmitrii A. A1 - Persheyev, Sydulla K. A1 - Kotliar, Konstantin T1 - False spectra formation in the differential two-channel scheme of the laser Doppler flowmeter JF - Biomedizinische Technik N2 - Noise in the differential two-channel scheme of a classic laser Doppler flowmetry (LDF) instrument was studied. Formation of false spectral components in the output signal due to beating of electrical signals in the differential amplifier was found out. The improved block-diagram of the flowmeter was developed allowing to reduce the noise. Y1 - 2018 U6 - https://doi.org/10.1515/bmt-2017-0060 SN - 0013-5585 VL - 63 IS - 4 SP - 439 EP - 444 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Lanzl, Ines M. A1 - Seidova, Seid-Fatima A1 - Maier, Mathias A1 - Schmidt-Trucksäss, Arno A1 - Halle, Martin A1 - Kotliar, Konstantin T1 - Dynamic retinal vessel response to flicker in age-related macular degeneration patients before and after vascular endothelial growth factor inhibitor injection JF - Acta Ophthalmologica Y1 - 2011 SN - 1755-3768 VL - 89 IS - 5 SP - 472 EP - 479 PB - Wiley CY - Weinheim ER - TY - CHAP A1 - Langohr, Philipp A1 - Bung, Daniel Bernhard A1 - Crookston, Brian M. ED - Ortega-Sánchez, Miguel T1 - Hybrid investigation of labyrinth weirs: Discharge capacity and energy dissipation T2 - Proceedings of the 39th IAHR World Congress N2 - The replacement of existing spillway crests or gates with labyrinth weirs is a proven techno-economical means to increase the discharge capacity when rehabilitating existing structures. However, additional information is needed regarding energy dissipation of such weirs, since due to the folded weir crest, a three-dimensional flow field is generated, yielding more complex overflow and energy dissipation processes. In this study, CFD simulations of labyrinth weirs were conducted 1) to analyze the discharge coefficients for different discharges to compare the Cd values to literature data and 2) to analyze and improve energy dissipation downstream of the structure. All tests were performed for a structure at laboratory scale with a height of approx. P = 30.5 cm, a ratio of the total crest length to the total width of 4.7, a sidewall angle of 10° and a quarter-round weir crest shape. Tested headwater ratios were 0.089 ≤ HT/P ≤ 0.817. For numerical simulations, FLOW-3D Hydro was employed, solving the RANS equations with use of finite-volume method and RNG k-ε turbulence closure. In terms of discharge capacity, results were compared to data from physical model tests performed at the Utah Water Research Laboratory (Utah State University), emphasizing higher discharge coefficients from CFD than from the physical model. For upstream heads, some discrepancy in the range of ± 1 cm between literature, CFD and physical model tests was identified with a discussion regarding differences included in the manuscript. For downstream energy dissipation, variable tailwater depths were considered to analyze the formation and sweep-out of a hydraulic jump. It was found that even for high discharges, relatively low downstream Froude numbers were obtained due to high energy dissipation involved by the three-dimensional flow between the sidewalls. The effects of some additional energy dissipation devices, e.g. baffle blocks or end sills, were also analyzed. End sills were found to be non-effective. However, baffle blocks with different locations may improve energy dissipation downstream of labyrinth weirs. Y1 - 2022 SN - 978-90-832612-1-8 U6 - https://doi.org/10.3850/IAHR-39WC252171192022738 SN - 2521-7119 (print) SN - 2521-716X (online) N1 - 39th IAHR World Congress, 19. - 24. Juni 2022, Granada SP - 2313 EP - 2318 PB - International Association for Hydro-Environment Engineering and Research (IAHR) CY - Madrid ER - TY - JOUR A1 - Langen, Karl J. A1 - Ziemons, Karl A1 - Kiwit, Jürgen C. W. A1 - Herzog, Hans A1 - Kuwert, Torsten A1 - Bock, Wolfgang A1 - Stöcklin, Gerhard A1 - Feinendegen, Ludwig E. A1 - Müller-Gärtner, Hans-W. T1 - 3-[123I]iodo-α-methyltyrosine and [methyl-11C]-L-methionine uptake in cerebral gliomas: a compara-tive study using SPECT and PET JF - Journal of Nuclear Medicine Y1 - 1997 SN - 0161-5505 VL - 38 IS - 4 SP - 517 EP - 522 ER - TY - JOUR A1 - Landers, Ernst Ulrich A1 - Kern, Alexander T1 - Future evolution of risk management for structures : Advancement for the future IEC 62305-2 Ed3 Y1 - 2011 N1 - XI International Symposium on Lightning Protection (SIPDA), Fortaleza (Brasilien), 2011. SP - 1 EP - 6 PB - IEEE CY - New York ER - TY - CHAP A1 - Land, Ingmar A1 - Hoeher, Peter Adam A1 - Gligorevic, Snjezana T1 - Computation of symbol-wise mutual information in transmission systems with logAPP decoders and application to EXIT charts T2 - 5th International ITG Conference on Source and Channel Coding (SCC) : January 14 - 16, 2004, Erlangen ; conference record. (ITG-Fachbericht ; 181) Y1 - 2004 SN - 3-8007-2802-8 SP - 195 EP - 202 PB - VDE-Verl. CY - Berlin [u.a.] ER - TY - CHAP A1 - Lahrs, Lennart A1 - Krisam, Pierre A1 - Herrmann, Ulf T1 - Envisioning a collaborative energy system planning platform for the energy transition at the district level T2 - ECOS 2023. The 36th International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems N2 - Residential and commercial buildings account for more than one-third of global energy-related greenhouse gas emissions. Integrated multi-energy systems at the district level are a promising way to reduce greenhouse gas emissions by exploiting economies of scale and synergies between energy sources. Planning district energy systems comes with many challenges in an ever-changing environment. Computational modelling established itself as the state-of-the-art method for district energy system planning. Unfortunately, it is still cumbersome to combine standalone models to generate insights that surpass their original purpose. Ideally, planning processes could be solved by using modular tools that easily incorporate the variety of competing and complementing computational models. Our contribution is a vision for a collaborative development and application platform for multi-energy system planning tools at the district level. We present challenges of district energy system planning identified in the literature and evaluate whether this platform can help to overcome these challenges. Further, we propose a toolkit that represents the core technical elements of the platform. Lastly, we discuss community management and its relevance for the success of projects with collaboration and knowledge sharing at their core. KW - Energy system planning KW - District energy planning platform KW - District data model KW - Renewable energy integration Y1 - 2023 U6 - https://doi.org/10.52202/069564-0284 N1 - ECOS 2023. The 36th International Conference on Efficiency, Cost, Optimization, Simulation and Environmental Impact of Energy Systems, 25-30 JUNE, 2023, Las Palmas de Gran Canaria, Spain SP - 3163 EP - 3170 PB - Procedings of ECOS 2023 ER - TY - JOUR A1 - Lagemaat, Miriam W. A1 - Vos, Eline K. A1 - Maas, Marnix C. A1 - Bitz, Andreas A1 - Orzada, Stephan A1 - Uden, Mark J. van A1 - Kobus, Thiele A1 - Heerschap, Arend A1 - Scheenen, Tom W. J. T1 - Phosphorus magnetic resonance spectroscopic imaging at 7 T in patients with prostate cancer JF - Investigative Radiology N2 - Objectives The aim of this study was to identify characteristics of phosphorus (³¹P) spectra of the human prostate and to investigate changes of individual phospholipid metabolites in prostate cancer through in vivo ³¹P magnetic resonance spectroscopic imaging (MRSI) at 7 T. Materials and Methods In this institutional review board–approved study, 15 patients with biopsy-proven prostate cancer underwent T₂-weighted magnetic resonance imaging and 3-dimensional ³¹P MRSI at 7 T. Voxels were selected at the tumor location, in normal-appearing peripheral zone tissue, normal-appearing transition zone tissue, and in the base of the prostate close to the seminal vesicles. Phosphorus metabolite ratios were determined and compared between tissue types. Results Signals of phosphoethanolamine (PE) and phosphocholine (PC) were present and well resolved in most ³¹P spectra in the prostate. Glycerophosphocholine signals were observable in 43% of the voxels in malignant tissue, but in only 10% of the voxels in normal-appearing tissue away from the seminal vesicles. In many spectra, independent of tissue type, 2 peaks resonated in the chemical shift range of inorganic phosphate, possibly representing 2 separate pH compartments. The PC/PE ratio in the seminal vesicles was highly elevated compared with the prostate in 5 patients. A considerable overlap of ³¹P metabolite ratios was found between prostate cancer and normal-appearing prostate tissue, preventing direct discrimination of these tissues. The only 2 patients with high Gleason scores tumors (≥4+5) presented with high PC and glycerophosphocholine levels in their cancer lesions. Conclusions Phosphorus MRSI at 7 T shows distinct features of phospholipid metabolites in the prostate gland and its surrounding structures. In this exploratory study, no differences in ³¹P metabolite ratios were observed between prostate cancer and normal-appearing prostate tissue possibly because of the partial volume effects of small tumor foci in large MRSI voxels. Y1 - 2014 U6 - https://doi.org/10.1097/RLI.0000000000000012 SN - 1536-0210 VL - 49 IS - 5 SP - 363 EP - 372 PB - Lippincott Williams & Wilkins CY - Philadelphia, Pa. ER - TY - JOUR A1 - Lagemaat, Miriam W. A1 - Maas, Marnix C. A1 - Vos, Eline K. A1 - Bitz, Andreas A1 - Orzada, Stephan A1 - Weiland, Elisabeth A1 - Uden, Mark J. van A1 - Kobus, Thiele A1 - Heerschap, Arend A1 - Scheenen, Tom W. J. T1 - (31) P MR spectroscopic imaging of the human prostate at 7 T: T1 relaxation times, Nuclear Overhauser Effect, and spectral characterization JF - Magnetic Resonance in Medicine Y1 - 2015 U6 - https://doi.org/10.1002/mrm.25209 SN - 1522-2594 VL - 73 IS - 3 SP - 909 EP - 920 PB - Wiley CY - Weinheim ER - TY - JOUR A1 - Lagemaat, Miriam W. A1 - Breukels, Vincent A1 - Vos, Eline K. A1 - Kerr, Adam B. A1 - Uden, Mark J. van A1 - Orzada, Stephan A1 - Bitz, Andreas A1 - Maas, Marnix C. A1 - Scheenen, Tom W. J. T1 - ¹H MR spectroscopic imaging of the prostate at 7T using spectral-spatial pulses JF - Magnetic Resonance in Medicine N2 - Purpose To assess the feasibility of prostate ¹H MR spectroscopic imaging (MRSI) using low-power spectral-spatial (SPSP) pulses at 7T, exploiting accurate spectral selection and spatial selectivity simultaneously. Methods A double spin-echo sequence was equipped with SPSP refocusing pulses with a spectral selectivity of 1 ppm. Three-dimensional prostate ¹H-MRSI at 7T was performed with the SPSP-MRSI sequence using an 8-channel transmit array coil and an endorectal receive coil in three patients with prostate cancer and in one healthy subject. No additional water or lipid suppression pulses were used. Results Prostate ¹H-MRSI could be obtained well within specific absorption rate (SAR) limits in a clinically feasible time (10 min). Next to the common citrate signals, the prostate spectra exhibited high spermine signals concealing creatine and sometimes also choline. Residual lipid signals were observed at the edges of the prostate because of limitations in spectral and spatial selectivity. Conclusion It is possible to perform prostate ¹H-MRSI at 7T with a SPSP-MRSI sequence while using separate transmit and receive coils. This low-SAR MRSI concept provides the opportunity to increase spatial resolution of MRSI within reasonable scan times. Y1 - 2016 U6 - https://doi.org/10.1002/mrm.25569 SN - 1522-2594 VL - 75 IS - 3 SP - 933 EP - 945 PB - International Society for Magnetic Resonance in Medicine ER - TY - JOUR A1 - Laarmann, Lukas A1 - Thoma, Andreas A1 - Misch, Philipp A1 - Röth, Thilo A1 - Braun, Carsten A1 - Watkins, Simon A1 - Fard, Mohammad T1 - Automotive safety approach for future eVTOL vehicles JF - CEAS Aeronautical Journal N2 - The eVTOL industry is a rapidly growing mass market expected to start in 2024. eVTOL compete, caused by their predicted missions, with ground-based transportation modes, including mainly passenger cars. Therefore, the automotive and classical aircraft design process is reviewed and compared to highlight advantages for eVTOL development. A special focus is on ergonomic comfort and safety. The need for further investigation of eVTOL’s crashworthiness is outlined by, first, specifying the relevance of passive safety via accident statistics and customer perception analysis; second, comparing the current state of regulation and certification; and third, discussing the advantages of integral safety and applying the automotive safety approach for eVTOL development. Integral safety links active and passive safety, while the automotive safety approach means implementing standardized mandatory full-vehicle crash tests for future eVTOL. Subsequently, possible crash impact conditions are analyzed, and three full-vehicle crash load cases are presented. KW - eVTOL development KW - eVTOL safety KW - Crashworthiness KW - Automotive safety approach KW - Full-vehicle crash test Y1 - 2023 U6 - https://doi.org/10.1007/s13272-023-00655-0 SN - 1869-5590 (Online) SN - 1869-5582 (Print) N1 - Corresponding author: Lukas Laarmann PB - Springer Nature ER - TY - JOUR A1 - Laack, Walter van A1 - Refisch, A. T1 - Neuralgic amyotrophy of the lumbar area. Case Report / Refisch, A. ; Laack, W. van JF - Archives of Orthopaedic and Trauma Surgery. 108 (1989), H. 5 Y1 - 1989 SN - 0936-8051 SP - 329 EP - 332 ER - TY - JOUR A1 - Laack, Walter van T1 - Why natural constants are as they are JF - British journal of arts and social sciences Y1 - 2013 SN - 2046-9578 (E-Journal) VL - Vol. 15 IS - Nr. 2 SP - 198 EP - 203 PB - BritishJournal Publ. Inc CY - London ER - TY - JOUR A1 - Laack, Walter van T1 - The genetic code should be seen as a positioning code JF - British journal of arts and social sciences. Vol. 14 (2013), No. 1 Y1 - 2013 SN - 2046-9578 SP - 93 EP - 97 ER - TY - BOOK A1 - Laack, Walter van T1 - A better history of our world / Vol. 2. Life Y1 - 2002 SN - 978-3-8311-2597-5 N1 - [Eine bessere Geschichte unserer Welt ] PB - van Laack CY - Aachen ER - TY - BOOK A1 - Laack, Walter van T1 - A better history of our world / Vol. 1. The universe Y1 - 2001 SN - 978-3-8311-1490-0 N1 - [Eine bessere Geschichte unserer Welt ] PB - van Laack CY - Aachen ER - TY - BOOK A1 - Laack, Walter van T1 - Nobody ever dies! / 1. ed. Y1 - 2000 SN - 978-3-936624-03-8 PB - van Laack CY - Aachen ER -