TY  - CHAP
A1  - Simsek, Beril
A1  - Krause, Hans-Joachim
A1  - Engelmann, Ulrich M.
ED  - Digel, Ilya
ED  - Staat, Manfred
ED  - Trzewik, Jürgen
ED  - Sielemann, Stefanie
ED  - Erni, Daniel
ED  - Zylka, Waldemar
T1  - Magnetic biosensing with magnetic nanoparticles: Simulative approach to predict signal intensity in frequency mixing magnetic detection
T2  - 4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen
N2  - Magnetic nanoparticles (MNP) are investigated with great interest for biomedical applications in diagnostics (e.g. imaging: magnetic particle imaging (MPI)), therapeutics (e.g. hyperthermia: magnetic fluid hyperthermia (MFH)) and multi-purpose biosensing (e.g. magnetic immunoassays (MIA)). What all of these applications have in common is that they are based on the unique magnetic relaxation mechanisms of MNP in an alternating magnetic field (AMF). While MFH and MPI are currently the most prominent examples of biomedical applications, here we present results on the relatively new biosensing application of frequency mixing magnetic detection (FMMD) from a simulation perspective. In general, we ask how the key parameters of MNP (core size and magnetic anisotropy) affect the FMMD signal: by varying the core size, we investigate the effect of the magnetic volume per MNP; and by changing the effective magnetic anisotropy, we study the MNPs’ flexibility to leave its preferred magnetization direction. From this, we predict the most effective combination of MNP core size and magnetic anisotropy for maximum signal generation.
Y1  - 2024
SN  - 978-3-940402-65-3
U6  - http://dx.doi.org/10.17185/duepublico/81475
SP  - 27
EP  - 28
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Ruge, C.
A1  - Müller-Veggian, Mattea
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - A long-term stable macroporoustype EIS structure for electrochemical sensor applications
JF  - Sensors and Actuators B. 91 (2003), H. 1-3
Y1  - 2003
SN  - 0925-4005
SP  - 21
EP  - 25
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - New concepts of miniaturised reference electrodes in silicon technology for potentiometric sensor systems
JF  - Sensors and Actuators B. 103 (2004), H. 1-2
Y1  - 2004
SN  - 0925-4005
SP  - 429
EP  - 435
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - Strategies of miniaturised reference electrodes integrated in a silicon-based „one chip“ pH sensor
JF  - Sensors. 3 (2003), H. 9
Y1  - 2003
SN  - 1424-8220
SP  - 330
EP  - 339
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Krings, T.
A1  - Lüth, H.
A1  - Wang, J.
A1  - Schöning, Michael Josef
T1  - A „hybrid“ thin-film pH sensor with integrated thick-film reference
JF  - Sensors. 1 (2001), H. 6
Y1  - 2001
SN  - 1424-8220
SP  - 183
EP  - 192
ER  - 
TY  - JOUR
A1  - Simonis, A.
A1  - Dawgul, M.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Miniaturised reference electrodes for field-effect sensors compatible to silicon chip technology
JF  - Electrochimica Acta. 51 (2005), H. 5
Y1  - 2005
SN  - 0013-4686
U6  - http://dx.doi.org/10.1016/j.electacta.2005.04.063
SP  - 930
EP  - 937
ER  - 
TY  - JOUR
A1  - Sildatke, Michael
A1  - Karwanni, Hendrik
A1  - Kraft, Bodo
A1  - Zündorf, Albert
T1  - A distributed microservice architecture pattern for the automated generation of information extraction pipelines
JF  - SN Computer Science
N2  - Companies often build their businesses based on product information and therefore try to automate the process of information extraction (IE). Since the information source is usually heterogeneous and non-standardized, classic extract, transform, load techniques reach their limits. Hence, companies must implement the newest findings from research to tackle the challenges of process automation. They require a flexible and robust system that is extendable and ensures the optimal processing of the different document types. This paper provides a distributed microservice architecture pattern that enables the automated generation of IE pipelines. Since their optimal design is individual for each input document, the system ensures the ad-hoc generation of pipelines depending on specific document characteristics at runtime. Furthermore, it introduces the automated quality determination of each available pipeline and controls the integration of new microservices based on their impact on the business value. The introduced system enables fast prototyping of the newest approaches from research and supports companies in automating their IE processes. Based on the automated quality determination, it ensures that the generated pipelines always meet defined business requirements when they come into productive use.
KW  - Architectural design
KW  - Model-driven software engineering
KW  - Software and systems modeling
KW  - Enterprise information systems
KW  - Information extraction
Y1  - 2023
U6  - http://dx.doi.org/10.1007/s42979-023-02256-4
SN  - 2661-8907
N1  - Corresponding authors: Michael Sildatke, Hendrik Karwanni
IS  - 4, Article number: 833
PB  - Springer Singapore
CY  - Singapore
ER  - 
TY  - CHAP
A1  - Sildatke, Michael
A1  - Karwanni, Hendrik
A1  - Kraft, Bodo
A1  - Schmidts, Oliver
A1  - Zündorf, Albert
T1  - Automated Software Quality Monitoring in Research Collaboration Projects
T2  - ICSEW'20: Proceedings of the IEEE/ACM 42nd International Conference on Software Engineering Workshops
Y1  - 2020
U6  - http://dx.doi.org/10.1145/3387940.3391478
SP  - 603
EP  - 610
ER  - 
TY  - JOUR
A1  - Siepmann, Thomas
A1  - Schuh, G.
A1  - Levering, V.
T1  - PROPLAN / Schuh, G.; Siepmann, Th.; Levering, V.
JF  - Handbook on architectures of information systems : with 24 tables / Peter Bernus ... (ed.)
Y1  - 1998
SN  - 3-540-64453-9
N1  - International handbooks on information systems ; 1
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Siepmann, Thomas
A1  - Rupietta, D.
T1  - Closer to the customer with computerized  product support
JF  - Technische Mitteilungen Krupp (1993)
Y1  - 1993
CY  - Essen
ER  - 
TY  - BOOK
A1  - Siepmann, Thomas
T1  - Modeller for Value Systems
Y1  - 1997
PB  - Erasmus Universiteit Rotterdam
CY  - Rotterdam
ER  - 
TY  - JOUR
A1  - Siepmann, Thomas
T1  - Exploitation Plan of the TELEflow Project
Y1  - 1999
N1  - 4th Framework Programme Report
CY  - Brussels
ER  - 
TY  - CHAP
A1  - Siekmann, Thomas
A1  - Müller, Karsten
T1  - Adaptive potential of the stormwater management in urban areas faced by the climate change
T2  - 12th International Conference on Urban Drainage, Porto Alegre/Brazil, 11-16 September 2011
Y1  - 2011
ER  - 
TY  - JOUR
A1  - Sieker, Tim
A1  - Neuner, Andreas
A1  - Dimitrova, Darina
A1  - Tippkötter, Nils
A1  - Muffler, Kai
A1  - Bart, Hans-Jörg
A1  - Heinzle, Elmar
A1  - Ulber, Roland
T1  - Ethanol production from grass silage by simultaneous pretreatment, saccharification and fermentation: First steps in the process development
JF  - Engineering in Life Sciences
N2  - Grass silage provides a great potential as renewable feedstock. Two fractions of the grass silage, a press juice and the fiber fraction, were evaluated for their possible use for bioethanol production. Direct production of ethanol from press juice is not possible due to high concentrations of organic acids. For the fiber fraction, alkaline peroxide or enzymatic pretreatment was used, which removes the phenolic acids in the cell wall. In this study, we demonstrate the possibility to integrate the enzymatic pretreatment with a simultaneous saccharification and fermentation to achieve ethanol production from grass silage in a one-process step. Achieved yields were about 53 g ethanol per kg silage with the alkaline peroxide pretreatment and 91 g/kg with the enzymatic pretreatment at concentrations of 8.5 and 14.6 g/L, respectively. Furthermore, it was shown that additional supplementation of the fermentation medium with vitamins, trace elements and nutrient salts is not necessary when the press juice is directly used in the fermentation step.
Y1  - 2011
U6  - http://dx.doi.org/10.1002/elsc.201000160
N1  - Special Issue "Bioprocess‐oriented plant design"
VL  - 11
IS  - 4
SP  - 436
EP  - 442
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - CHAP
A1  - Siegert, Petra
A1  - Pohl, Martina
A1  - Kneen, Malea M.
A1  - Pogozheva, Irina D.
A1  - Kenyon, George L.
A1  - McLeish, Michael J.
T1  - Exploring the substrate specificity of benzoylformate decarboxylase, pyruvate decarboxylase, and benzaldehyde lyase
T2  - Thiamine : catalytic mechanisms in normal and disease states / ed. by Frank Jordan ...
Y1  - 2004
SN  - 0-8247-4062-9
SP  - 275
EP  - 290
PB  - Dekker
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Siegert, Petra
A1  - McLeish, Michael J.
A1  - Baumann, Martin
A1  - Iding, Hans
A1  - Kneen, Malea M.
A1  - Kenyon, George L.
A1  - Pohl, Martina
T1  - Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida
JF  - Protein engineering, design, and selection : peds
Y1  - 2005
SN  - 1460-213X (E-Journal); 1741-0134 (E-Journal); 0269-2139 (Print); 1741-0126 (Print)
VL  - Vol. 18
IS  - Iss. 7
SP  - 345
EP  - 357
ER  - 
TY  - CHAP
A1  - Siegert, Petra
A1  - Iding, Hans
A1  - Baumann, Martin
A1  - McLeish, Michael J.
A1  - Kenyon, George L.
A1  - Pohl, Martina
T1  - Broadening of the substrate spectra of two ThDP-dependent decarboxylases using site-directed-mutagenesis
T2  - Proceedings of the 4th International Congress on Biochemical Engineering : 17 and 18 February 2000, Stuttgart
Y1  - 2000
SN  - 3-8167-5570-4
SP  - 38
EP  - 42
ER  - 
TY  - CHAP
A1  - Siebigteroth, Ines
A1  - Kraft, Bodo
A1  - Schmidts, Oliver
A1  - Zündorf, Albert
T1  - A Study on Improving Corpus Creation by Pair Annotation
T2  - Proceedings of the Poster Session of the 2nd Conference on Language, Data and Knowledge (LDK-PS 2019)
Y1  - 2019
SN  - 1613-0073
SP  - 40
EP  - 44
ER  - 
TY  - CHAP
A1  - Sherelkhan, Dinara
A1  - Alibekova, Alina
ED  - Digel, Ilya
ED  - Staat, Manfred
ED  - Trzewik, Jürgen
ED  - Sielemann, Stefanie
ED  - Erni, Daniel
ED  - Zylka, Waldemar
T1  - EEM spectroscopy characterization of humic substances of biomedical importance
T2  - 4th YRA MedTech Symposium 2024 : February 1 / 2024 / FH Aachen
N2  - Humic substances possess distinctive chemical features enabling their use in many advanced applications, including biomedical fields. No chemicals in nature have the same combination of specific chemical and biological properties as humic substances. Traditional medicine and modern research have demonstrated that humic substances from different sources possess immunomodulatory and anti-inflammatory properties, which makes them suitable for the prevention and treatment of chronic dermatoses, allergic rhinitis, atopic dermatitis, and other conditions characterized by inflammatory and allergic responses [1-4]. The use of humic compounds as agentswith antifungal and antiviral properties shows great potential [5-7].
Y1  - 2024
SN  - 978-3-940402-65-3
U6  - http://dx.doi.org/10.17185/duepublico/81475
SP  - 31
EP  - 32
PB  - Universität Duisburg-Essen
CY  - Duisburg
ER  - 
TY  - CHAP
A1  - Shahidi, Parham
A1  - Pfaff, Raphael
A1  - Enning, Manfred
T1  - The connected wagon - a concept for the  integration of vehicle side sensors and actors with cyber physical  representation for condition based maintenance
T2  - First International Conference on Rail Transportation
Y1  - 2017
N1  - 2017 ICRT;
International Conference on Rail Transportation <1, 2017, Chengdu, China>
SP  - 1
EP  - 8
ER  -