TY  - JOUR
A1  - Wittmann, Klaus
T1  - Overview of Space Operations at DLR
Y1  - 2000
N1  - SpaceOps2000 Conference, Toulouse, Frankreich,19-23 June 2000
ER  - 
TY  - CHAP
A1  - Wittig, M.
A1  - Rütters, René
A1  - Bragard, Michael
ED  - Reiff-Stephan, Jörg
ED  - Jäkel, Jens
ED  - Schwarz, André
T1  - Application of RL in control systems using the example of a rotatory inverted pendulum
T2  - Tagungsband AALE 2024 : Fit für die Zukunft: praktische Lösungen für die industrielle Automation
N2  - In this paper, the use of reinforcement learning (RL) in control systems is investigated using a rotatory inverted pendulum as an example. The control behavior of an RL controller is compared to that of traditional LQR and MPC controllers. This is done by evaluating their behavior under optimal conditions, their disturbance behavior, their robustness and their development process. All the investigated controllers are developed using MATLAB and the Simulink simulation environment and later deployed to a real pendulum model powered by a Raspberry Pi. The RL algorithm used is Proximal Policy Optimization (PPO). The LQR controller exhibits an easy development process, an average to good control behavior and average to good robustness. A linear MPC controller could show excellent results under optimal operating conditions. However, when subjected to disturbances or deviations from the equilibrium point, it showed poor performance and sometimes instable behavior. Employing a nonlinear MPC Controller in real time was not possible due to the high computational effort involved. The RL controller exhibits by far the most versatile and robust control behavior. When operated in the simulation environment, it achieved a high control accuracy. When employed in the real system, however, it only shows average accuracy and a significantly greater performance loss compared to the simulation than the traditional controllers. With MATLAB, it is not yet possible to directly post-train the RL controller on the Raspberry Pi, which is an obstacle to the practical application of RL in a prototyping or teaching setting. Nevertheless, RL in general proves to be a flexible and powerful control method, which is well suited for complex or nonlinear systems where traditional controllers struggle.
KW  - Rotatory Inverted Pendulum
KW  - MPC
KW  - LQR
KW  - PPO
KW  - Reinforcement Learning
Y1  - 2024
SN  - 978-3-910103-02-3
U6  - http://dx.doi.org/10.33968/2024.53
N1  - 20. AALE-Konferenz. Bielefeld, 06.03.-08.03.2024.
(Tagungsband unter https://doi.org/10.33968/2024.29)
SP  - 241
EP  - 248
PB  - le-tex publishing services GmbH
CY  - Leipzig
ER  - 
TY  - BOOK
A1  - Witte, Bertold
A1  - Sparla, Peter
T1  - Vermessungskunde und Grundlagen der Statistik für das Bauwesen
Y1  - 2011
SN  - 978-3-87907-497-6
PB  - Wichmann
CY  - Heidelberg
ET  - 7., überarb. erw. Aufl.
ER  - 
TY  - JOUR
A1  - Witt, Klaus
A1  - Bogner, D.
T1  - Druckmessung mit zukunftsorientierten Perspektiven
JF  - Sensor Report. 5 (1990), H. 1
Y1  - 1990
SN  - 0179-9592
SP  - 8
EP  - 14
ER  - 
TY  - JOUR
A1  - Wissenbach, U.
A1  - Six, S.
A1  - Bongaerts, Johannes
A1  - Ternes, D.
A1  - Steinwachs, S.
A1  - Unden, G.
T1  - A third periplasmic transport system for l-arginine in Escherichia coli: molecular characterization of the artPIQMJ genes, arginine binding and transport
JF  - Molecular microbiology
Y1  - 1995
SN  - 1365-2958 (E-Journal); 0950-382x (Print)
VL  - Vol. 17
IS  - Iss. 4
SP  - 675
EP  - 686
ER  - 
TY  - JOUR
A1  - Wissen, M.
A1  - Bogdanski, N.
A1  - Scheer, H.-C.
A1  - Bitz, Andreas
A1  - Ahrens, G.
A1  - Gruetzner, G.
T1  - Implication of the light polarisation for UV curing of pre-patterned resists
JF  - Microelectronic Engineering
Y1  - 2005
U6  - http://dx.doi.org/10.1016/j.mee.2004.12.099
SN  - 0167-9317
VL  - 78-79
SP  - 659
EP  - 664
ER  - 
TY  - BOOK
A1  - Winkler, Norbert
T1  - Zahlentafeln für den Baubetrieb / Hoffmann, Manfred [Hrsg.]. 6., vollst. aktualisierte Aufl. ... Norbert Winkler [Bearb.]
Y1  - 2002
SN  - 3-519-55220-5
PB  - Teubner
CY  - Stuttgart [u.a.]
ER  - 
TY  - JOUR
A1  - Winkler, Norbert
T1  - Vermessung zur Bauzeit der Zitadelle und heute : Bastion Wilhelmus / von Norbert Winkler
JF  - 4 Bastionen, 4 Aspekte : aktuelle Arbeiten zur Zitadelle Jülich ; Katalog zur Ausstellung im Hexenturm 10.11.95 - 14.02.96 / [Veranst.: Stadtgeschichtliches Museum Jülich]. Mit Beitr. von Guido von Büren ... [Hrsg.: Marcell Perse]
Y1  - 1995
N1  - Führer des Stadtgeschichtlichen Museums Jülich ; 7
SP  - 77
EP  - 115
CY  - Jülich
ER  - 
TY  - JOUR
A1  - Winkler, Norbert
T1  - Vermessung
JF  - Zahlentafeln für den Baubetrieb / Hoffmann, Manfred ; Kuhlmann, Willy [Hrsg.]. 7., vollst. überarb. Aufl.
Y1  - 2006
SN  - 3-519-65220-X
N1  - Kapitel 3
SP  - 147
EP  - 160
PB  - Teubner
CY  - Wiesbaden
ER  - 
TY  - JOUR
A1  - Winkler, Norbert
T1  - Vermessung
JF  - Beispiele für die Baubetriebspraxis / Hoffmann, Manfred ; Kuhlmann, Willy [Hrsg.].
Y1  - 2006
SN  - 978-3-8351-0002-2
N1  - Kapitel 2
SP  - 9
EP  - 34
PB  - Teubner
CY  - Wiesbaden
ER  - 
TY  - CHAP
A1  - Winkler, Norbert
T1  - Vermessung
T2  - Zahlentafeln für den Baubetrieb
Y1  - 2016
SN  - 978-3-658-02838-1 (Online)
SN  - 978-3-658-02837-4 (Print)
U6  - http://dx.doi.org/10.1007/978-3-658-02838-1_3
SP  - 159
EP  - 177
PB  - Springer Vieweg
CY  - Wiesbaden
ET  - 9., überarb. und aktual. Aufl.
ER  - 
TY  - JOUR
A1  - Wingens, Niklas
A1  - May, Jörg
A1  - Pfaff, Raphael
T1  - Betrieblich-technische Innovationsansätze zur Bremsprobe nach einer Prozessänderung
JF  - Eisenbahntechnische Rundschau : ETR ; Zeitschrift für die gesamte Eisenbahntechnik
Y1  - 2019
SN  - 0013-2845
IS  - 5
PB  - DVV Media Group
CY  - Hamburg
ER  - 
TY  - JOUR
A1  - Winckler, Silvia
A1  - Krueger, Rolf
A1  - Schnitzler, Thomas
A1  - Zang, Werner
A1  - Fischer, Rainer
A1  - Biselli, Manfred
T1  - A sensitive monitoring system for mammalian cell cultivation processes: a PAT approach
JF  - Bioprocess and biosystems engineering
N2  - Biopharmaceuticals such as antibodies are produced in cultivated mammalian cells, which must be monitored to comply with good manufacturing practice. We, therefore, developed a fully automated system comprising a specific exhaust gas analyzer, inline analytics and a corresponding algorithm to precisely determine the oxygen uptake rate, carbon dioxide evolution rate, carbon dioxide transfer rate, transfer quotient and respiratory quotient without interrupting the ongoing cultivation, in order to assess its reproducibility. The system was verified using chemical simulation experiments and was able to measure the respiratory activity of hybridoma cells and DG44 cells (derived from Chinese hamster ovary cells) with satisfactory results at a minimum viable cell density of ~2.0 × 10⁵ cells ml⁻¹. The system was suitable for both batch and fed-batch cultivations in bubble-aerated and membrane-aerated reactors, with and without the control of pH and dissolved oxygen.
Y1  - 2014
U6  - http://dx.doi.org/10.1007/s00449-013-1062-8
SN  - 1615-7591 (Print) 1615-7605 (Online)
VL  - 37
IS  - 5
SP  - 901
EP  - 912
PB  - Springer
CY  - Berlin, Heidelberg
ER  - 
TY  - JOUR
A1  - Wilson, Thomas L
A1  - Blome, Hans-Joachim
A1  - LaFave, Norman
T1  - Astrophysical Cosmology Using a Lunar Ligo
JF  - Engineering, construction, and operations in space V : proceedings of the Fifth International Conference on Space '96, Albuquerque, New Mexico, June 1-6, 1996 / sponsored by Aerospace Division of the American Society of Civil Engineers ... [et al.]; edite
Y1  - 1996
SN  - 0-7844-0177-2
SP  - 861
EP  - 863
PB  - The Society
CY  - New York
ER  - 
TY  - JOUR
A1  - Wilson, T. L.
A1  - Blome, Hans-Joachim
T1  - The Pioneer anomaly and a rotating Gödel universe
JF  - Advances in Space Research
Y1  - 2009
SN  - 0273-1177
VL  - 44
IS  - 11
SP  - 1345
EP  - 1353
ER  - 
TY  - JOUR
A1  - Wilson, Ian D.
A1  - Wilson, Claire E.
A1  - Scheer, Nico
A1  - Dickie, A.P.
A1  - Schreiter, K.
A1  - Wilson, E. M.
A1  - Riley, R. J.
A1  - Wehr, R.
A1  - Bial, J.
T1  - The Pharmacokinetics and Metabolism of Lumiracoxib in Chimeric Humanized and Murinized FRG Mice
JF  - Biochemical pharmacology
Y1  - 2017
U6  - http://dx.doi.org/10.1016/j.bcp.2017.03.015
SN  - 1873-2968
VL  - Volume 135
SP  - 139
EP  - 150
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Wilson, C. E.
A1  - Dickie, A. P.
A1  - Schreiter, K.
A1  - Wehr, R.
A1  - Wilson, E. M.
A1  - Bial, J.
A1  - Scheer, Nico
A1  - Wilson, I. D.
A1  - Riley, R. J.
T1  - The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice
JF  - Archives of Toxicology
N2  - The pharmacokinetics of diclofenac were investigated following single oral doses of 10 mg/kg to chimeric liver humanized and murinized FRG and C57BL/6 mice. In addition, the metabolism and excretion were investigated in chimeric liver humanized and murinized FRG mice. Diclofenac reached maximum blood concentrations of 2.43 ± 0.9 µg/mL (n = 3) at 0.25 h post-dose with an AUCinf of 3.67 µg h/mL and an effective half-life of 0.86 h (n = 2). In the murinized animals, maximum blood concentrations were determined as 3.86 ± 2.31 µg/mL at 0.25 h post-dose with an AUCinf of 4.94 ± 2.93 µg h/mL and a half-life of 0.52 ± 0.03 h (n = 3). In C57BL/6J mice, mean peak blood concentrations of 2.31 ± 0.53 µg/mL were seen 0.25 h post-dose with a mean AUCinf of 2.10 ± 0.49 µg h/mL and a half-life of 0.51 ± 0.49 h (n = 3). Analysis of blood indicated only trace quantities of drug-related material in chimeric humanized and murinized FRG mice. Metabolic profiling of urine, bile and faecal extracts revealed a complex pattern of metabolites for both humanized and murinized animals with, in addition to unchanged parent drug, a variety of hydroxylated and conjugated metabolites detected. The profiles in humanized mice were different to those of both murinized and wild-type animals, e.g., a higher proportion of the dose was detected in the form of acyl glucuronide metabolites and much reduced amounts as taurine conjugates. Comparison of the metabolic profiles obtained from the present study with previously published data from C57BL/6J mice and humans revealed a greater, though not complete, match between chimeric humanized mice and humans, such that the liver humanized FRG model may represent a model for assessing the biotransformation of such compounds in humans.
Y1  - 2018
U6  - http://dx.doi.org/10.1007/s00204-018-2212-1
SN  - 1432-0738
VL  - 92
IS  - 6
SP  - 1953
EP  - 1967
PB  - Springer
ER  - 
TY  - JOUR
A1  - Wilming, Anja
A1  - Begemann, Jens
A1  - Kuhne, Stefan
A1  - Regestein, Lars
A1  - Bongaerts, Johannes
A1  - Evers, Stefan
A1  - Maurer, Karl-Heinz
A1  - Büchs, Jochen
T1  - Metabolic studies of γ-polyglutamic acid production in Bacillus licheniformis by small-scale continuous cultivations
JF  - Biochemical engineering journal
Y1  - 2013
SN  - 1873-295X (E-Journal); 1369-703X (Print)
VL  - Vol. 73
SP  - 29
EP  - 37
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Willms, Herbert
A1  - Beer, Stefan
A1  - Fröhlke, K.
A1  - Haidn, O.J.
A1  - [u.a.], 
T1  - Regelung eines Wasserstoff-/Sauerstoff-Dampferzeugers mit Hilfe eines modifizierten Zirkondioxid-Sensors
Y1  - 1993
N1  - Report: Deutsche Forschungsanstalt für Luft- und Raumfahrt, EN-CA/E (1993) Seite 1-17 (17 Seiten, 14 Bilder, 2 Tabellen, 14 Quellen)
ER  - 
TY  - BOOK
A1  - Willms, Herbert
A1  - Beer, Stefan
T1  - Regelung eines H2/O2-Dampferzeugers
Y1  - 1993
N1  - Forschungsbericht / Deutsche Forschungsanstalt für Luft- und Raumfahrt ; 93-02 ; als Ms. gedr.
PB  - DLR, Zentrale Allgemeine Dienste, Versand
CY  - Köln
ER  -