TY  - JOUR
A1  - Mennicken, Max
A1  - Peter, Sophia Katharina
A1  - Kaulen, Corinna
A1  - Simon, Ulrich
A1  - Karthäuser, Silvia
T1  - Controlling the Electronic Contact at the Terpyridine/Metal Interface
JF  - The Journal of Physical Chemistry C
Y1  - 2019
U6  - http://dx.doi.org/10.1021/acs.jpcc.9b05865
SN  - 1932-7455
VL  - 123
IS  - 35
SP  - 21367
EP  - 21375
ER  - 
TY  - JOUR
A1  - Mennicken, Max
A1  - Peter, Sophia K.
A1  - Kaulen, Corinna
A1  - Simon, Ulrich
A1  - Karthäuser, Silvia
T1  - Transport through Redox-Active Ru-Terpyridine Complexes Integrated in Single Nanoparticle Devices
JF  - The Journal of Physical Chemistry C
N2  - Transition metal complexes are electrofunctional molecules due to their high conductivity and their intrinsic switching ability involving a metal-to-ligand charge transfer. Here, a method is presented to contact reliably a few to single redox-active Ru-terpyridine complexes in a CMOS compatible nanodevice and preserve their electrical functionality. Using hybrid materials from 14 nm gold nanoparticles (AuNP) and bis-{4′-[4-(mercaptophenyl)-2,2′:6′,2″-terpyridine]}-ruthenium(II) complexes a device size of 30² nm² inclusive nanoelectrodes is achieved. Moreover, this method bears the opportunity for further downscaling. The Ru-complex AuNP devices show symmetric and asymmetric current versus voltage curves with a hysteretic characteristic in two well separated conductance ranges. By theoretical approximations based on the single-channel Landauer model, the charge transport through the formed double-barrier tunnel junction is thoroughly analyzed and its sensibility to the molecule/metal contact is revealed. It can be verified that tunneling transport through the HOMO is the main transport mechanism while decoherent hopping transport is present to a minor extent.
Y1  - 2020
U6  - http://dx.doi.org/10.1021/acs.jpcc.9b11716
SN  - 1932-7455
VL  - 124
IS  - 8
SP  - 4881
EP  - 4889
PB  - ACS Publications
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Martinez, Ronny
A1  - Jakob, Felix
A1  - Tu, Ran
A1  - Siegert, Petra
A1  - Maurer, Karl-Heinz
A1  - Schwaneberg, Ulrich
T1  - Increasing activity and thermal resistance of Bacillus gibsonii alkaline protease (BgAP) by directed evolution
JF  - Biotechnology and bioengineering
Y1  - 2013
SN  - 1097-0290 (E-Journal); 0006-3592 (Print); 0368-1467 (Print)
VL  - Vol. 110
IS  - Iss. 3
SP  - 711
EP  - 720
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Malzahn, Kerstin
A1  - Windmiller, Joshua Ray
A1  - Valdés-Ramírez, Gabriela
A1  - Wang, Joseph
A1  - Schöning, Michael Josef
T1  - Wearable electrochemical sensors for in situ analysis in marine environments
JF  - Analyst. 136 (2011), H. 14
Y1  - 2011
SN  - 0003-2654
SP  - 2912
EP  - 2917
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Maezawa, Koichi
A1  - Förster, Arnold
T1  - Quantum transport devices based on resonant tunneling
JF  - Nanoelectronics and information technology : advanced electronic materials and novel devices / Rainer Waser (ed.).
Y1  - 2003
SN  - 3-527-40363-9
SP  - 407
EP  - 424
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Lüth, H.
A1  - Thust, M.
A1  - Steffen, A.
A1  - Kordos, P.
A1  - Schöning, Michael Josef
T1  - Biochemical sensors with structured and porous silicon capacitors
JF  - Materials Science and Engineering B. 69-70 (2000)
Y1  - 2000
SN  - 0921-5107
SP  - 104
EP  - 108
ER  - 
TY  - JOUR
A1  - Leinhos, Marcel
A1  - Schusser, Sebastian
A1  - Bäcker, Matthias
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
T1  - Micromachined multi-parameter sensor chip for the control of polymer-degradation medium
JF  - Physica Status Solidi (A) : special issue on engineering and functional interfaces
N2  - It is well known that the degradation environment can strongly influence the biodegradability and kinetics of biodegradation processes of polymers. Therefore, besides the monitoring of the degradation process, it is also necessary to control the medium in which the degradation takes place. In this work, a micromachined multi-parameter sensor chip for the control of the polymer-degradation medium has been developed. The chip combines a capacitive field-effect pH sensor, a four-electrode electrolyte-conductivity sensor and a thin-film Pt-temperature sensor. The results of characterization of individual sensors are presented. In addition, the multi-parameter sensor chip together with an impedimetric polymer-degradation sensor was simultaneously characterized in degradation solutions with different pH and electrolyte conductivity. The obtained results demonstrate the feasibility of the multi-parameter sensor chip for the control of the polymer-degradation medium.
Y1  - 2014
U6  - http://dx.doi.org/10.1002/pssa.201330364
SN  - 1521-396X (E-Journal); 1862-6319 (E-Journal); 0031-8965 (Print); 1862-6300 (Print)
VL  - 211
IS  - 6
SP  - 1346
EP  - 1351
PB  - Wiley-VCH
CY  - Weinheim
ER  - 
TY  - JOUR
A1  - Küppers, Tobias
A1  - Steffen, Victoria
A1  - Hellmuth, Hendrik
A1  - O'Connell, Timothy
A1  - Bongaerts, Johannes
A1  - Maurer, Karl-Heinz
A1  - Wiechert, Wolfgang
T1  - Developing a new production host from a blueprint: Bacillus pumilus as an industrial enzyme producer
JF  - Microbial cell factories
Y1  - 2014
U6  - http://dx.doi.org/10.1186/1475-2859-13-46
SN  - 1475-2859 (E-Journal)
VL  - 13
SP  - Article No. 46
PB  - BioMed Central
CY  - London
ER  - 
TY  - JOUR
A1  - Kurowski, A.
A1  - Schultze, J.W.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Micro- and nanopatterning of sensor chips by means of macroporous silicon
JF  - Transducers '01 Eurosensors XV : digest of technical papers / the 11th International Conference on Solid-State Sensors and Actuators, June 10-14, 2001, Munich, Germany. Ernst Obermeier (Ed.)
Y1  - 2001
SN  - 3-540-42150-5
N1  - Eurosensors (15, 2001, München) ; International Conference on Solid State Sensors and Actuators (11, 2001, München)
SP  - 640
EP  - 643
PB  - Springer
CY  - Berlin [u.a.]
ER  - 
TY  - JOUR
A1  - Kurowski, A.
A1  - Schultze, J.
A1  - Lüth, H.
A1  - Schöning, Michael Josef
T1  - Micro- and nanopatterning of sensor chips by means of macroporous silicon.
JF  - Sensors and Actuators B. 83 (2002), H. 1-3
Y1  - 2002
SN  - 0925-4005
N1  - Selected Papers from TRANSDUCERS '01 EUROSENSORS XV
SP  - 123
EP  - 128
ER  - 
TY  - JOUR
A1  - Krämer, Melina
A1  - Pita, Marcos
A1  - Zhou, Jian
A1  - Ornatska, Maryna
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
T1  - Coupling of Biocomputing Systems with Electronic Chips: Electronic Interface for Transduction of Biochemical Information
JF  - Journal of Physical Chemistry C: Nanomaterials and Interfaces. 113 (2009), H. 6
Y1  - 2009
SN  - 1932-7455
SP  - 2573
EP  - 2579
PB  - American Cemical Society
CY  - Washington, DC
ER  - 
TY  - JOUR
A1  - Krämer, Marco
A1  - Bongaerts, Johannes
A1  - Bovenberg, Roel
A1  - Kremer, Susanne
A1  - Müller, Ulrike
A1  - Orf, Sonja
A1  - Wubbolts, Marcel
A1  - Raeven, Leon
T1  - Metabolic engineering for microbial production of shikimic acid
JF  - Metabolic engineering
Y1  - 2003
SN  - 1096-7184 (E-Journal); 1096-7176 (Print)
VL  - Vol. 5
IS  - Iss. 4
SP  - 277
EP  - 283
ER  - 
TY  - CHAP
A1  - Kreyer, Jörg
A1  - Stollenwerk, Dominik
A1  - Schöning, Michael Josef
T1  - Tagung des Forschernachwuchses der FH Aachen 20. November 2013 / ed.: J. Kreyer, D. Stollenwerk, M. J. Schöning
Y1  - 2013
PB  - FH Aachen
CY  - Aachen
ER  - 
TY  - JOUR
A1  - Kramer, Friederike
A1  - Halamkova, Lenka
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Katz, Evgeny
A1  - Halamek, Jan
T1  - Biocatalytic analysis of biomarkers for forensic identification of ethnicity between Caucasian and African American
JF  - The analyst. August 2013
Y1  - 2013
SN  - 1364-5528 (E-Journal); 0003-2654 (Print)
VL  - Vol. 138
SP  - 6251
EP  - 6257
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Krafft, B.
A1  - Förster, Arnold
A1  - Hart, A. van der
A1  - Schäpers, T.
T1  - Control of Aharonov-Bohm oscillations in a AlGaAs/GaAs ring by asymmetric and symmetric gate biasing
JF  - Physica E: Low-dimensional Systems and Nanostructures. 9 (2001), H. 4
Y1  - 2001
SN  - 1386-9477
SP  - 635
EP  - 641
ER  - 
TY  - CHAP
A1  - Koch, Claudia
A1  - Poghossian, Arshak
A1  - Wege, Christina
A1  - Schöning, Michael Josef
ED  - Wege, Christina
T1  - TMV-Based Adapter Templates for Enhanced Enzyme Loading in Biosensor Applications
T2  - Virus-Derived Nanoparticles for Advanced Technologies
N2  - Nanotubular tobacco mosaic virus (TMV) particles and RNA-free lower-order coat protein (CP) aggregates have been employed as enzyme carriers in different diagnostic layouts and compared for their influence on biosensor performance. In the following, we describe a label-free electrochemical biosensor for improved glucose detection by use of TMV adapters and the enzyme glucose oxidase (GOD). A specific and efficient immobilization of streptavidin-conjugated GOD ([SA]-GOD) complexes on biotinylated TMV nanotubes or CP aggregates was achieved via bioaffinity binding. Glucose sensors with adsorptively immobilized [SA]-GOD, and with [SA]-GOD cross-linked with glutardialdehyde, respectively, were tested in parallel on the same sensor chip. Comparison of these sensors revealed that TMV adapters enhanced the amperometric glucose detection remarkably, conveying highest sensitivity, an extended linear detection range and fastest response times. These results underline a great potential of an integration of virus/biomolecule hybrids with electronic transducers for applications in biosensorics and biochips. Here, we describe the fabrication and use of amperometric sensor chips combining an array of circular Pt electrodes, their loading with GOD-modified TMV nanotubes (and other GOD immobilization methods), and the subsequent investigations of the sensor performance.
KW  - Tobacco mosaic virus (TMV)
KW  - Coat protein
KW  - Enzyme nanocarrier
KW  - Glucose biosensor
KW  - Glucose oxidase
Y1  - 2018
SN  - 978-1-4939-7808-3
U6  - http://dx.doi.org/10.1007/978-1-4939-7808-3
N1  - Methods in Molecular Biology, vol 1776
SP  - 553
EP  - 568
PB  - Humana Press
CY  - New York, NY
ER  - 
TY  - JOUR
A1  - Koch, Claudia
A1  - Poghossian, Arshak
A1  - Schöning, Michael Josef
A1  - Wege, Christian
T1  - Penicillin Detection by Tobacco Mosaic Virus-Assisted Colorimetric Biosensors
JF  - Nanotheranostics
N2  - The presentation of enzymes on viral scaffolds has beneficial effects such as an increased enzyme loading and a prolonged reusability in comparison to conventional immobilization platforms. Here, we used modified tobacco mosaic virus (TMV) nanorods as enzyme carriers in penicillin G detection for the first time. Penicillinase enzymes were conjugated with streptavidin and coupled to TMV rods by use of a bifunctional biotin-linker. Penicillinase-decorated TMV particles were characterized extensively in halochromic dye-based biosensing. Acidometric analyte detection was performed with bromcresol purple as pH indicator and spectrophotometry. The TMV-assisted sensors exhibited increased enzyme loading and strongly improved reusability, and higher analysis rates compared to layouts without viral adapters. They extended the half-life of the sensors from 4 - 6 days to 5 weeks and thus allowed an at least 8-fold longer use of the sensors. Using a commercial budget-priced penicillinase preparation, a detection limit of 100 µM penicillin was obtained. Initial experiments also indicate that the system may be transferred to label-free detection layouts.
Y1  - 2018
U6  - http://dx.doi.org/10.7150/ntno.22114
SN  - 2206-7418
VL  - 2
IS  - 2
SP  - 184
EP  - 196
PB  - Ivyspring
CY  - Sydney
ER  - 
TY  - JOUR
A1  - Knobbe, D.-T.
A1  - Schöning, Michael Josef
A1  - Poghossian, Arshak
A1  - Mourzina, Y.
T1  - Charakterisierung von kapazitiven EMISSensoren mittels Impedanzspektroskopie, Kapazitäts-Spannungs- und Konstant-Kapazitäts-Messung
JF  - Sensoren und Messsysteme 2004 : Tagung Ludwigsburg, 15. und 16. März 2004 / VDI-VDE-Gesellschaft Mess- und Automatisierungstechnik
Y1  - 2004
SN  - 3-18-091829-2
N1  - Auch erschienen als: VDI-Berichte ; 1829
SP  - 851
EP  - 854
PB  - VDI
CY  - Düsseldorf
ER  - 
TY  - CHAP
A1  - Kloock, Joachim P.
A1  - Schöning, Michael Josef
T1  - Heavy metal detection with semiconductor devices based on PLD-prepared chalcogenide glass thin films
T2  - Armenian Journal of Physics
Y1  - 2007
SN  - 1829-1171
SP  - 95
EP  - 98
ER  - 
TY  - CHAP
A1  - Kloock, Joachim P.
A1  - Schubert, J.
A1  - Ermelenko, Y.
A1  - Vlasov, Y. G.
A1  - Bratov, A.
A1  - Schöning, Michael Josef
T1  - Thin-film sensors with chalcogenide glass materials – a general survey
T2  - Biochemical sensing utilisation of micro- and nanotechnologies : Warsaw, [23rd - 26th] November 2005 / ed. by M. Mascini ...
Y1  - 2006
SP  - 92
EP  - 97
CY  - Warsaw
ER  -